Dr. Amir Ghaemi
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Dr. Amir Ghaemi

Research Scientist
Golestan University of Medical Sciences, Iran

Highest Degree
Ph.D. in Molecular Virology from Tarbiat Modares University, Iran

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Biography

Dr. Amir Ghaemi obtained his Ph.D. in Molecular Virology from Tarbiat Modares University, Iran. Currently he is working as Assistant Professor at Golestan University of Medical Sciences, Iran, and Biotechnology Manager of Hi-tech Center, Minister of Industries and Mines. His area of research interest related to Nanocarriers and Gene Delivery Systems, and Gene and Stem Cell Therapy. Dr. Amir received number of honors includes Ranked 1st among 480 examinees for the M.Sc. entrance exam, held by the Iranian Ministry of Science, Research and Technology, PhD Scholarship from Ministry of Health and Medical Education, Iran National Elite foundation member, Outstanding National Student Award of Iran, The Best Researcher of Golestan province, and The Best Researcher of Golestan University of Medical Sciences. He also received many grants for his research work. He has published 21 research articles in ISI journals, 11 articles in Persian, 12 papers in scientific meeting, 1 patent and 1 book contributed as author/co-author. He successfully supervised 5 MSc students.

Area of Interest:

Biomedical Sciences
100%
Microbiology
62%
Virology
90%
Infection and Immunity
75%
Neurobiology
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
0
Abstracts
0

Selected Publications

  1. Togha, M., M. Jahanshahi, L. Alizadeh, S.R. Jahromi and G. Vakilzadeh et al., 2017. Rapamycin augments immunomodulatory properties of bone marrow-derived mesenchymal stem cells in experimental autoimmune encephalomyelitis. Mol. Neurobiol., 54: 2445-2457.
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  2. Moeini, S., M. Saeidi, F. Fotouhi, M. Mondanizadeh and S. Shirian et al., 2017. Synergistic effect of programmed cell death protein 1 blockade and secondary lymphoid tissue chemokine in the induction of anti-tumor immunity by a therapeutic cancer vaccine. Arch. Virol., 162: 333-346.
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  3. Ghaemi, A., L. Alizadeh, S. Babaei, M. Jafarian and M.K. Ghadiri,et al, 2017. Astrocyte-mediated inflammation in cortical spreading depression. Cephalalgia, (In Press). 10.1177/0333102417702132.
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  4. Fotouhi, F., M. Shaffifar, B. Farahmand, S. Shirian and M. Saeidi et al., 2017. Adjuvant use of the NKT cell agonist alpha-galactosylceramide leads to enhancement of M2-based DNA vaccine immunogenicity and protective immunity against influenza A virus. Arch. Virol., 162: 1251-1260.
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  5. Vakilzadeh, G., F. Khodagholi, T. Ghadiri, A. Ghaemi, F. Noorbakhsh, M. Sharifzadeh and A. Gorji, 2016. The effect of melatonin on behavioral, molecular, and histopathological changes in cuprizone model of demyelination. Mol. Neurobiol., 53: 4675-4684.
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  6. Ghaemi, A., A. Sajadian, B. Khodaie, A.A. Lotfinia and M. Lotfinia et al., 2016. Immunomodulatory effect of Toll-like receptor-3 ligand poly I:C on cortical spreading depression. Mol. Neurobiol., 53: 143-154.
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  7. Gableh, F., M. Saeidi, S. Hemati, K. Hamdi, H. Soleimanjahi, A. Gorji and A. Ghaemi, 2016. Combination of the toll like receptor agonist and α-galactosylceramide as an efficient adjuvant for cancer vaccine. J. Biomed. Sci., Vol. 23. 10.1186/s12929-016-0238-3.
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  8. Vakilzadeh, G., F. Khodagholi, T. Ghadiri, M. Darvishi and A. Ghaemi et al., 2015. Protective effect of a cAMP analogue on behavioral deficits and neuropathological changes in cuprizone model of demyelination. Mol. Neurobiol., 52: 130-141.
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  9. Tahamtan, A., A. Tabarraei, A. Moradi, M. Dinarvand, M. Kelishadi, A. Ghaemi and F. Atyabi, 2015. Chitosan nanoparticles as a potential nonviral gene delivery for HPV-16 E7 into mammalian cells. Artif. Cells Nanomed. Biotechnol., 43: 366-372.
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  10. Shaffifar, M., A. Tabarraei, A. Sajadian, F. Fotouhi and A. Ghaemi, 2015. Immunologic evaluation of DNA vaccine encoding influenza virus M2 gene in type A-influenza mice model. Med. Lab. J., 9: 9-16.
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  11. Tahamtan, A., A. Ghaemi, A. Gorji, H.R. Kalhor and A. Sajadian et al., 2014. Antitumor effect of therapeutic HPV DNA vaccines with chitosan-based nanodelivery systems. J. Biomed. Sci., Vol. 21. 10.1186/s12929-014-0069-z.
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  12. Sajadian, A., A. Tabarraei, H. Soleimanjahi, F. Fotouhi, A. Gorji and A. Ghaemi, 2014. Comparing the effect of Toll-like receptor agonist adjuvants on the efficiency of a DNA vaccine. Arch. Virol., 159: 1951-1960.
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  13. Saeedi, A., A. Ghaemi, A. Tabarraei, A. Moradi and A. Gorji et al., 2014. Enhanced cell immune responses to hepatitis C virus core by novel heterologous DNA prime/lambda nanoparticles boost in mice. Virus Genes, 49: 11-21.
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  14. Jahromi, S.R., S.R. Arrefhosseini, A. Ghaemi, A. Alizadeh, H.M. Tabriz and M. Togha, 2014. Alleviation of experimental allergic encephalomyelitis in C57BL/6 mice by soy daidzein. Iran. J. Allergy Asthma Immunol., 13: 256-264.
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  15. Gorzin, Z., A.A. Gorzin, A. Tabarraei, N. Behnampour, S. Irani and A. Ghaemi, 2014. Immunogenicity evaluation of a DNA vaccine expressing the hepatitis C virus non-structural protein 2 gene in C57BL/6 mice. Iran. Biomed. J., 18: 1-7.
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  16. Bahrami, A.A., A. Ghaemi, A. Tabarraei, A. Sajadian, A. Gorji and H. Soleimanjahi, 2014. DNA vaccine encoding HPV-16 E7 with mutation in LYCYE pRb-binding motif induces potent anti-tumor responses in mice. J. Virol. Methods, 206: 12-18.
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  17. Tahamtan, A., A. Moradi, A. Ghaemi, M. Kelishadi, H. Ghafari and P. Hashemi, 2013. Seroepidemiology of hepatitis E virus in hemodialysis patients in Gorgan-Iran. Med. Lab. J., 7: 13-17.
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  18. Naziri, H., A. Tabarraei, A. Ghaemi, M. Davarpanah, N Javid and A. Moradi, 2013. Drug-resistance-associated mutations and HIV sub-type determination in drug-Naive and HIV-positive patients under treatment with antiretroviral drugs. Med. Lab. J., 7: 1-8.
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  19. Naderi, M., A. Saeedi, A. Moradi, M. Kleshadi, M.R. Zolfaghari, A. Gorji and A. Ghaemi, 2013. Interleukin-12 as a genetic adjuvant enhances hepatitis C virus NS3 DNA vaccine immunogenicity. Virol. Sin., 28: 167-173.
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  20. Farzanehpour, M., H. Soleimanjahi, Z.M. Hassan, A. Amanzadeh and A. Ghaemi et al., 2013. HSP70 modified response against HPV based tumor. Eur. Rev. Med. Pharmacol. Sci., 17: 228-234.
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  21. Moradi, A., S. Zhand, A. Ghaemi, N. Javid and A. Tabarraei, 2012. Mutations in the S gene region of hepatitis B virus genotype D in golestan province-Iran. Virus Genes, 44: 382-387.
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  22. Ghaemi, A., H. Soleimanjahi, S. Razeghi, A. Gorji and A. Tabaraei et al., 2012. Genistein induces a protective immunomodulatory effect in a mouse model of cervical cancer. Iran. J. Immunol., 9: 119-127.
    PubMed  |  
  23. Ghaemi, A., A. Tabaraei, P. Gill, H. Soleimanjahi and A. Gorji, 2012. Lambda phage nanoparticles for targetomics. Biotechnology, 11: 95-99.
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  24. Ghaemi, A., H. Soleimanjahi, P. Gill, Z.M. Hassan, S. Razeghi, M. Fazeli and S.M. Razavinikoo, 2011. Protection of mice by a λ-based therapeutic vaccine against cancer associated with human papillomavirus type 16. Intervirology, 54: 105-112.
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  25. Fazeli, M., H. Soleimanjahi, A. Ghaemi, M. Farzanepour and A. Amanzadeh et al., 2011. Efficacy of HPV-16 E7 based vaccine in a TC-1 tumoric animal model of cervical cancer. Cell J., 12: 483-488.
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  26. Khansarinejad, B., H. Soleimanjahi, A. Ghaemi, T. Tiraihi and S.P. Beiranvand, 2010. Localization of herpes simplex virus type 1 DNA in latently infected BALB/c mice neurons using in situ polymerase chain reaction. Iran. Biomed. J., 14: 83-88.
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  27. Hasani, S.A.R., K. Hamdi, N. Ordouzadeh, G. Amir and M. Isa, 2010. Inhibitory effect of green and black teas ethyl acetate extracts on helicobacter pylori the causative agent of peptic ulcers. J. Qazvin Univ. Med. Sci., 13: 12-18.
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  28. Ghaemi, A., H. Soleimanjahi, P. Gill, Z. Hassan, S.R.M. Jahromi and F. Roohvand, 2010. Recombinant λ-phage nanobioparticles for tumor therapy in mice models. Genet. Vaccines Therapy, Vol. 8. 10.1186/1479-0556-8-3.
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  29. Hassani, A.S., N. Amirmozafari and A. Ghaemi, 2009. Virulence Increasing of Salmonella Typhimurium in Balb/c Mice After Heat-Stress Induction of Phage Shock Protein A. Curr. Microbiol., 59: 446-450.
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  30. Hassani, A.S., F. Malekzadeh, N. Amirmozafari, K. Hamdi and N. Ordouzadeh et al., 2009. Phage Shock Protein G, a Novel Ethanol-Induced Stress Protein in Salmonella Typhimurium. Curr Microbiol., 58: 239-244.
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  31. Ghaemi, A., H. Soleimanjahi, P. Gill, E. Arefian, S. Soudi and Z. Hassan, 2009. Echinacea purpurea polysaccharide reduces the latency rate in herpes simplex virus type-1 infections. Intervirology, 52: 29-34.
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  32. Ghaemi, A., H. Soleimanjahi, P. Gil, Z.M. Hassan and F. Rouhvand, 2009. Design and construction of recombinant phage nanobioparticles as a candidate vehicle for oral-gene vaccine delivery. Bimon. Off. Publ. Med. Daneshvar, 16: 1-6.
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  33. Arefian, E., T. Bamdad, H. Soleimanjahi, M.R. Akhoond and M. Parsania et al., 2009. A kinetic study of gamma interferon production in herpes simplex virus-1 DNA prime-protein boost regimen comparing to DNA or subunit vaccination. Mol. Biol., 43: 388-393.
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  34. Hassani, A.S., K. Hamdi and A. Ghaemi, 2008. In vitro reduction in colonization of streptococcus mutans by honey beeswax ethyl acetate extract. Arak Med. Univ. J., 11: 87-95.
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  35. Gill, P., M. Ghalami, A. Ghaemi, N. Mosavari and H. Abdul-Tehrani et al., 2008. Nanodiagnostic method for colorimetric detection of Mycobacterium tuberculosis 16S rRNA. NanoBiotechnology, 4: 28-35.
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  36. Gill, P. and A. Ghaemi, 2008. Nucleic acid isothermal amplification technologies-a review. Nucleosides Nucleotides Nucleic Acids, 27: 224-243.
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  37. Meshkani, R., M. Taghikhani, B. Larijani, Y. Bahrami and S. Khatami et al., 2007. Pro12Ala polymorphism of the peroxisome proliferator-activated receptor-γ2 (PPARγ-2) gene is associated with greater insulin sensitivity and decreased risk of type 2 diabetes in an Iranian population. Clin. Chem. Lab. Med., 45: 477-482.
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  38. Gill, P., M. Amini, A. Ghaemi, L. Shokouhizadeh and H. Abdul-Tehrani et al., 2007. Detection of Helicobacter pylori by enzyme-linked immunosorbent assay of thermophilic helicase-dependent isothermal DNA amplification. Diagn. Microbiol. Infect. Dis., 59: 243-249.
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  39. Ghaemi, A., H. Soleimanjahi, T. Bamdad, S. Soudi and E. Arefeian et al., 2007. Induction of humoral and cellular immunity against latent HSV-1 infections by DNA immunization in BALB/c mice. Comp. Immunol. Microbiol. Infect. Dis., 30: 197-210.
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  40. Arefian, E., T. Bamdad, H. Soleimanjahi, F. Sabahi and M.R. Akhoond et al., 2007. Evaluation of γ-interferon kinetics in HSV-1 infected mice in different days post infection (in vivo) and post re-stimulation (in vitro). Comp. Immunol. Microbiol. Infect. Dis., 30: 1-9.
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  41. Gill, P., R. Ramezani, M.V.P. Amiri, A. Ghaemi and T. Hashempour et al., 2006. Enzyme-linked immunosorbent assay of nucleic acid sequence-based amplification for molecular detection of M. tuberculosis. Biochem. Biophys. Res. Commun., 347: 1151-1157.
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