Dr. Ayman Hussein
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Dr. Ayman Hussein

Researcher
An-Najah National University, Palestine

Highest Degree
Ph.D. in Biochemistry from University of Hamburg, Germany

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Area of Interest:

Biomedical Sciences
100%
Biochemistry Research
62%
Molecular Biology
90%
Parasitology
75%
Immunology
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
0
Abstracts
0

Selected Publications

  1. Burmeister, C., K. Luersen, A. Heinick, A. Hussein, M. Domagalski, R.D. Walter and E. Liebau, 2008. Oxidative stress in Caenorhabditis elegans: Protective effects of the Omega class glutathione transferase (GSTO-1). FASEB J., 22: 343-354.
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  2. Selkirk, M.E., O. Lazari, A.S. Hussein and J.B. Matthews, 2005. Nematode acetylcholinesterases are encoded by multiple genes and perform non-overlapping functions. Chem.-Biol. Interact., 157: 263-268.
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  3. Hussein, A.S., 2005. Inhibition of glutathione biosynthesis by buthionine sulfoximine. An-Najah Univ. J. Res. (N. Sci.), 19: 83-90.
  4. Selkirk, M.E., A.S. Hussein, A.E. Chambers, D. Goulding and M.P. Gares et al., 2004. Trichinella spiralis secretes a homologue of prosaposin. Mol. Biochem. Parasitol., 135: 49-56.
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  5. Lazari, O., A.S. Hussein, M.E. Selkirk, A.J. Davidson, F.J. Thompson and J.B. Matthews, 2003. Cloning and expression of two secretory acetylcholinesterases from the bovine lungworm, Dictyocaulus viviparous. Mol. Biochem. Parasitol., 132: 83-92.
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  6. Hussein, A.S., M. Harel and M.E. Selkirk, 2002. A distinct family of acetylcholinesterases is secreted by Nippostrongylus brasiliensis. Mol. Biochem. Parasitol., 123: 125-134.
    CrossRef  |  PubMed  |  Direct Link  |  
  7. Hussein, A.S., K. Kichenin and M.E. Selkirk, 2002. Suppression of secreted acetylcholinesterase expression in Nippostrongylus brasiliensis by RNA interference. Mol. Biochem. Parasitol., 122: 91-94.
    CrossRef  |  PubMed  |  Direct Link  |  
  8. Villatte, F., T.T. Bachman, A.S. Hussein and R.D. Schmid, 2001. Acetylcholinesterase assay for rapid expression screening in liquid and solid media. Biotechniques, 30: 81-86.
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  9. Villatte, F., A. Hussein, T. Bachmann and R. Schmid, 2001. Expression level of heterologous proteins in Pichia pastoris is influenced by flask design. Applied Microbiol. Biotechnol., 55: 463-465.
    CrossRef  |  Direct Link  |  
  10. Selkirk, M.E., S.M. Henson, W.S. Russell and A.S. Hussein, 2001. Acetylcholinesterase Secretion by Parasitic Nematodes. In: Parasitic Nematodes-Molecular Biology, Biochemistry and Immunology, Kennedy, M.W. and W. Harnett (Eds.)., CAB International, Wallingford, Oxon, pp: 211-228.
  11. Vella, M., E. Slater, L. Abu-Safieh, A.S. Hussein and P. Greenwell, 2000. The application of databases and PCR in the cloning of glycosidase genes from the protozoan Tritrichomonas foetus. Mol. Biotechnol., 15: 1-10.
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  12. Selkirk, M.E. and A.S. Hussein, 2000. Acetylcholinesterases of Gastrointestinal Nematodes. In: Biology of Parasitism: Modern Approaches, Tschudi, C. and E.J. Pearce (Eds.)., Kluwer Academic Publishers, Norwell, MA., pp: 121-142.
  13. Russell, W.S., S.M. Henson, A.S. Hussein, J.R. Tippins and M.E. Selkirk, 2000. Nippostrongylus brasiliensis: Infection induces upregulation of acetylcholinesterase activity on rat intestinal epithelial cells. Exp. Parasitol., 96: 222-230.
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  14. Luersen, K., S. Muller, A. Hussein, E. Liebau and R.D. Walter, 2000. The γ-glutamylcysteine synthetase of Onchocerca volvulus. Mol. Biochem. Parasitol., 111: 243-251.
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  15. Hussein, A.S., A.M. Smith, M.R. Chacon and M.E. Selkirk, 2000. Determinants of substrate specificity of a second non‐neuronal secreted acetylcholinesterase from the parasitic nematode Nippostrongylus brasiliensis. Eur. J. Biochem., 267: 2276-2282.
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  16. Hussein, A.S., M.R. Chacon, A.M. Smith, R. Tosado-Acevedo and M.E. Selkirk, 1999. Cloning, expression and properties of a nonneuronal secreted acetylcholinesterase from the parasitic nematode Nippostrongylus brasiliensis. J. Biol. Chem., 274: 9312-9319.
    CrossRef  |  Direct Link  |  
  17. Hussein, A.S., M.E. Grigg and M.E. Selkirk, 1999. Nippostrongylus brasiliensis: Characterisation of a somatic amphiphilic acetylcholinesterase with properties distinct from the secreted enzymes. Exp. Parasitol., 91: 144-150.
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  18. Selkirk, M.E., A.S. Hussein, W.S. Russell, M.E. Grigg and M.R. Chacon et al., 1998. Secreted Acetylcholinesterases from the Nematode Parasite Nippostrongylus brasiliensis: Properties and Implications for Mucosal Immunity. In: Structure and Function of Cholinesterases and Related Proteins, Doctor, B.P., P. Taylor, D.M. Quinn, R.L. Rotundo and M.K. Gentry (Eds.)., Plenum Press, New York, pp: 515-522.
  19. Grigg, M.E., L. Tang, A.S. Hussein and M.E. Selkirk, 1997. Characterisation of monomeric (G1) forms of acetylcholinesterase secreted by Nippostrongylus brasiliensis. Mol. Biochem. Parasitol., 90: 513-524.
  20. Hussein, A.S. and R.D. Walter, 1996. Purification and characterization of γ-glutamyl transpeptidase from Ascaris suum. Mol. Biochem. Parasitol., 77: 41-47.
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  21. Hussein, A.S. and R.D. Walter, 1996. Inhibition of glutathione synthesis of Ascaris suum by buthionine sulfoximine. Parasitol. Res., 82: 372-374.
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  22. Hussein, A.S. and R.D. Walter, 1995. Purification and characterization of γ-glutamylcysteine synthetase from Ascaris suum. Mol. Biochem. Parasitol., 72: 57-64.
    CrossRef  |  Direct Link  |  
  23. Hussein, A.S., S.K. Abdel-Hafez and A.M. Khalil, 1994. Isolation and characterization of excretory/secretory products from in vitro developmental stages of Echinococcus granulosus. Jap. J. Parasitol., 43: 82-89.
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