Dr. Wael Abdullah Alanazi
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Dr. Wael Abdullah Alanazi

Assistant Professor
King Saud University, Saudi Arabia


Highest Degree
Ph.D. in Pharmacology from University of Louisiana, US

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Biography

Wael Alanazi earned his Bachelor’s degree in Pharmaceutical Sciences from King Saud University in 2011. After graduation, Wael worked for the Drug Sector at Saudi Food and Drug Authority (SFDA) for evaluation of the quality of pharmaceutical products. In 2012, he worked as a teaching assistant in Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University. In 2013, Wael started his doctoral research in Department of Basic Pharmaceutical Sciences, School of Pharmacy, University of Louisiana at Monroe, USA. He joined Dr. Jackson’s laboratory and completed his thesis in title “The role of recurrent insulin-induced hypoglycemia on renal prostanoids production, (pro)renin receptor expression and oxidative stress in heart and kidney”. In 2016, Wael earned his Ph.D. in Pharmacology and published several peer-reviewed articles. Now, Dr. Wael works as an assistant professor in College of Pharmacy, King Saud University.

Area of Interest:

Pharmacology and Toxicology
100%
Pharmacology
62%
Therapeutic Strategies
90%
Diabetes
75%
Anti-diabetic
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
0
Abstracts
0

Selected Publications

  1. Nadeem, A., S.F. Ahmad, N.O. Al-Harbi, A.M. El-Sherbeeny and A.F. Alasmari et al., 2020. Bruton's tyrosine kinase inhibitor suppresses imiquimod-induced psoriasis-like inflammation in mice through regulation of IL-23/IL-17A in innate immune cells. Int. Immunopharmacol., Vol. 80. 10.1016/j.intimp.2020.106215.
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  2. Nadeem, A., S.F. Ahmad, N.O. Al-Harbi, M.M. Al-Harbi and K.E. Ibrahim et al., 2019. Inhibition of spleen tyrosine kinase signaling protects against acute lung injury through blockade of NADPH oxidase and IL-17A in neutrophils and γδ T cells respectively in mice. Int. Immunopharmacol., 68: 39-47.
    CrossRef  |  Direct Link  |  
  3. Imam, F., N.O. Al-Harbi, M.M. Al-Harbi, M.A. Ansari and A.F. Al-Asmari et al., 2018. Apremilast prevent doxorubicin-induced apoptosis and inflammation in heart through inhibition of oxidative stress mediated activation of NF-κB signaling pathways. Pharmacol. Rep., 70: 993-1000.
    CrossRef  |  Direct Link  |  
  4. Fakhruddin, S., W.A. Alanazi, H.N. Alhamami, K.P. Briski and K.E. Jackson, 2018. Hyperglycaemia induced by chronic I.P. and oral glucose loading leads to hypertension through increased Na+ retention in proximal tubule. Exp. Physiol., 103: 236-249.
    CrossRef  |  Direct Link  |  
  5. Alotaibi, M.R., Z.K. Hassan, S.S. Al-Rejaie, M.A. Alshammari and M.M. Almutairi et al., 2018. Characterization of apoptosis in a breast cancer cell line after IL-10 silencing. Asian Pac. J. Cancer Prev., 19: 777-783.
    Direct Link  |  
  6. Alasmari, F., M.A. Alshammari, A.F. Alasmari, W.A. Alanazi and K. Alhazzani, 2018. Neuroinflammatory cytokines induce amyloid beta neurotoxicity through modulating amyloid precursor protein levels/metabolism. BioMed Res. Int., Vol. 2018. 10.1155/2018/3087475.
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  7. Al-Harbi, N.O., A. Nadeem, S.F. Ahmad, M.R. Alotaibi and A.F. Alasmari et al., 2018. Short chain fatty acid, acetate ameliorates sepsis-induced acute kidney injury by inhibition of NADPH oxidase signaling in T cells. Int. Immunopharmacol., 58: 24-31.
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  8. Ahmad, S.F., M.A. Ansari, A. Nadeem, S.A. Bakheet and M.Z. Alzahrani et al., 2018. Resveratrol attenuates pro-inflammatory cytokines and activation of JAK1-STAT3 in BTBR T+ Itpr3tf/J autistic mice. Eur. J. Pharmacol., 829: 70-78.
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  9. Fakhruddin, S., W.A. Alanazi and K.E. Jackson, 2017. Development of a chronic hyperglycemic and hypertensive rat model through repetitive intraperitoneal and oral glucose loading. Int. J. Curr. Res., 9: 48786-48793.
  10. Fakhruddin, S., W. Alanazi and K.E. Jackson, 2017. Diabetes-induced reactive oxygen species: Mechanism of their generation and role in renal injury. J. Diabet. Res., Vol. 2017. 10.1155/2017/8379327.
    CrossRef  |  Direct Link  |  
  11. Almutairi, M.M., W.A. Alanazi, M.A. Alshammari, M.R. Alotaibi and A.R. Alhoshani et al., 2017. Neuro-protective effect of rutin against cisplatin-induced neurotoxic rat model. BMC Complementary Altern. Med., Vol. 17. 10.1186/s12906-017-1976-9.
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  12. Alanazi, W.A., M.B. Uddin, S. Fakhruddin and K.E. Jackson, 2017. Recurrent insulin-induced hypoglycemia enhances AngII and COX2 leading to renal PRR expression and oxidative stress in the heart and kidney. Int. J. Med., 5: 71-78.
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  13. Alanazi, W.A., S. Fakhruddin and K.E. Jackson, 2016. The role of recurrent insulin-induced hypoglycemia on renal prostanoid production. Ann. Res. Rev. Biol., 11: 1-9.
  14. Alanazi, W.A., S. Fakhruddin and K.E. Jackson, 2016. Acute angiotensin II infusion promotes local production of prostaglandin E2 and reactive species in the renal cortex. Innovat. J. Med. Health Sci., 6: 146-151.
  15. Alanazi, W., S. Fakhruddin and K.E. Jackson, 2016. Microdialysis sampling of renal interstitial fluid in acute studies. Int. J. Biol., 8: 69-79.
  16. Prathipati, P., W. Alanazi, D.W. Jackson and K.E. Jackson, 2015. Role of interstitial angiotensin II and ATP in mediating renal injury induced by recurrent insulin induced hypoglycemia. Ann. Res. Rev. Biol., 6: 328-336.
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