Dr. Ayat Badr Al-Ghafari
My Social Links

Dr. Ayat Badr Al-Ghafari

Assistant Professor and Vice Dean
King Abdulaziz University, Saudi Arabia

Highest Degree
Ph.D. in Biomedical Sciences from University of Nottingham, UK

Share this Profile

Area of Interest:

Molecular Sciences
100%
Molecular Biology
62%
Proteomics
90%
Genomics
75%
Drug Resistance
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
0
Abstracts
0

Selected Publications

  1. Zahrani, S.M., U.M. Omar, S.A. Rahimulddin, A.B. Al-Ghafari and H.A. Al Doghaither, 2019. Antiproliferative and apoptotic effects of the natural alkaline water (Zamzam) in breast cancer cell line MCF-7. J. Cancer Res. Therap., 10.4103/jcrt.JCRT_381_17.
    CrossRef  |  Direct Link  |  
  2. Siddiqui, H., A. Al-Ghafari, H. Choudhry, S. AlTurki, H. Alshibi, H. Al Doghaither and H. Alsufiani, 2019. Long noncoding RNAs as prognostic markers for colorectal cancer in Saudi patients. Genet. Testing Mol. Biomarkers, 23: 509-514.
    CrossRef  |  Direct Link  |  
  3. Al-Ghafari, A.B., 2019. Genetic variants of calcium sensing receptor gene and risk of colorectal cancer: A case-control study. Pak. J. Med. Sci., 35: 448-453.
    CrossRef  |  Direct Link  |  
  4. Abdulkhaleq, M.M., A.B. Al-Ghafari, A. Yezerski, H.A. Al Doghaither, A.M. Abusanad and U.M. Omar, 2019. Novel association between heterozygous genotype of single nucleotide polymorphism C218T in drug transporter ABCC1 gene and increased risk of colon cancer. Saudi Med. J., 40: 224-229.
    CrossRef  |  Direct Link  |  
  5. Ye, G., H. Luo, Z. Ren, M.S. Ahmad and C.G. Liu et al., 2018. Evaluating the bioenergy potential of Chinese Liquor-industry waste through pyrolysis, thermogravimetric, kinetics and evolved gas analyses. Energy Convers. Manage., 163: 13-21.
    CrossRef  |  Direct Link  |  
  6. Rasool, M., A. Malik, A.A. Ghuman, M.A.B. Ashraf and M. Arooj et al., 2018. Implications of isoprostanes and matrix metalloproteinase-7 having potential role in the development of colorectal cancer in males. Front. Oncol., Vol. 8. 10.3389/fonc.2018.00205.
    CrossRef  |  Direct Link  |  
  7. Al Doghaither, H. and A. Al-Ghafari, 2018. Contribution of genetic variants of ABC transporters (ABCC1 and ABCG2) genes with the pathogenesis of colorectal cancer. Biosci. Biotechnol. Res. Asia., 15: 555-559.
  8. Omar, U.M., H.A. Al Doghaither, S.A. Rahimulddin, S.M. Al Zahrani and A.B. Al-Ghafari, 2017. In vitro cytotoxic and anticancer effects of Zamzam water in human lung cancer (A594) cell line. Malaysian J. Med. Sci., 24: 15-25.
    CrossRef  |  Direct Link  |  
  9. Kumosani, T.A., A.P. Iyer, A.B. Al-Ghafari and M.A. Zamzami, 2017. Association of telomerase activity with the prognosis of diabetes mellitus in saudi population. J. Exper. Biol. Agric. Sci., 5: 277-281.
  10. Kuerban, A., S.S. Yaghmoor, Y.Q. Almulaiky, Y.A. Mohamed and S.S.I. Razvi et al., 2017. Therapeutic effects of phytochemicals of brassicaceae for management of obesity. Br. J. Pharm. Res., 19:: 1-11.
  11. Elmorsy, E., A. Al-Ghafari, F.M. Almutairi, A.M. Aggour and W.G. Carter, 2017. Antidepressants are cytotoxic to rat primary blood brain barrier endothelial cells at high therapeutic concentrations. Toxicol. In Vitro, 44: 154-163.
    CrossRef  |  Direct Link  |  
  12. Elmorsy, E., A. Al-Ghafari, A.M. Aggour, S.M. Mosad, R. Khan and S. Amer, 2017. Effect of antipsychotics on mitochondrial bioenergetics of rat ovarian theca cells. Toxicol. Lett., 272: 94-100.
    CrossRef  |  Direct Link  |  
  13. Elmorsy, E., A. Al-Ghafari, A.M. Aggour, R. Khan and S. Amer, 2017. The role of oxidative stress in antipsychotics induced ovarian toxicity. Toxicol. In vitro, 44: 190-195.
    CrossRef  |  Direct Link  |  
  14. Elmorsy, E., A. Al-Ghafari, A. Helaly, A.S. Hisab, B. Oehrle and P.A. Smith, 2017. Therapeutic concentrations of antidepressants inhibit pancreatic beta-cell function via mitochondrial complex inhibition. Toxicol. Sci., 158: 286-301.
    Direct Link  |  
  15. Al-Ghafari, A.B., R.H. Alharbi, M.M. Al-Jehani, S.A. Bujeir, H.A. Al Doghaither and U.M. Omar, 2017. The effect of adding different concentrations of cows’ milk on the antioxidant properties of coffee. Biosci. Biotechnol. Res. Asia, 14: 177-184.
  16. Al-Ghafari, A.B. and G.H. Althaqafi, 2017. The effect of processing and roasting on the antioxidant activity of extracts from instant and ground coffee. Biosci. Biotechnol. Res. Asia, 14: 69-74.
    Direct Link  |  
  17. Al Doghaither, H.A., M.M. Alyousef, N.M. Al Selami, A.B. Al-Ghafari and U.M. Omar, 2017. Addition of evaporated milk alters antioxdant properties of most commonly consumed coffee in Saudi Arabia. Malay. Applied Biol., 46: 97-104.
    Direct Link  |  
  18. Al Doghaither, H.A., A.M. Almowalad, A.M. Shorbaji, A.B. Al-Ghafari and U.M. Omar, 2017. Assessment of the antioxidant properties of the most common coffee brews available in the local markets of the western region of Saudi Arabia. J. Exp. Biol. Agric. Sci., 5: 70-76.
    Direct Link  |  
  19. Rahimulddin, S.A., A.B. Al-Ghafari, H.A. Al Doghaither, U.M. Omar and S.M. Al Zahrani, 2016. Influence of pH and sterilization conditions on the inhibitory effects of zamzam water on the cell viability of cancer cells. J. Biol. Sci., 16: 229-235.
    CrossRef  |  Direct Link  |  
  20. Omar, U.M., A.M. Shorbaji, E.M. Arrait, T.D. Al Agha, H.F. Al-Marzouki, H.A. Al Doghaither and A.B. Al-Ghafari, 2016. Comparative study of the antioxidant activity of two popular green tea beverages available in the local market of Saudi Arabia. Nat. Sci., 8: 227-234.
    CrossRef  |  Direct Link  |  
  21. El-Morsy, M., A. Al-Ghafari, S.M. Attalla and L.L. Nwidu, 2016. Role of oxidative stress in antituberculous drugs (individuals and combined) cytotoxicity in HepG2 cells. Malays. Appl. Biol., 45: 151-158.
  22. Al-Ghafari, A.B., W. Punjaruk, L.C.D. Storer, D.J. Carrier, D. Hussein, B. Coyle and I.D. Kerr, 2016. Long-term exposure to irinotecan reduces cell migration in glioma cells. J. Neuro-Oncol., 127: 455-462.
    CrossRef  |  Direct Link  |  
  23. Al-Ghafari, A.B., A.M. Shorbaji, L.A. AL-Sarori, E.O. Baduwailan and A.A. Basaar et al., 2016. Phenolic contents and antioxidant activities of green tea with and without lemon. Nat. Sci., 8: 247-255.
    CrossRef  |  Direct Link  |  
  24. Al-Doghaither, H.A., A.B. Al-Ghafari, S.A. Rahimulddin, S.M. Al-Zahrani, A.M. Omar and U.M. Omar, 2016. Evaluation of the potential anticancer activity of Zamzam water in human colon cancer cell line. Cancer Oncol. Res., 4: 33-41.
  25. Al Doghaither, H.A., U.M. Omar, S.A. Rahimulddin and A.B. Al-Ghafari, 2016. Cytotoxic effects of aqueous extracts of urtica urens on most common cancer types in Saudi Arabia. J. Biol. Sci., 16: 242-246.
    CrossRef  |  Direct Link  |  
  26. Al-Harithy, R.N. and A.B. Al-Ghafari, 2014. Influence of combined genotypes of RETN G62A with C-180G and G299A polymorphisms on colon cancer risk. Cancer, 4: 79-86.
    Direct Link  |  
  27. Al-Harithy, R.N. and A.B. Al-Ghafari, 2010. Resistin in human colon cancer.Increased expression independently of resistin promoter C-180G genotype. Saudi Med. J., 31: 495-500.
    Direct Link  |