Dr. Ishfaq Ali Shah Bukhari
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Dr. Ishfaq Ali Shah Bukhari

Associate Professor
King Khalid University, Saudi Arabia

Highest Degree
Ph.D. in Pharmacology from University of Karachi, Pakistan

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Area of Interest:

Pharmacology and Toxicology
100%
Cardiovascular Disease
62%
Therapeutic Strategies
90%
Clinical Research
75%
Inflammation
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
51
Abstracts
0

Selected Publications

  1. Younis, W., Alamgeer, V.B. Schini-Kerth, S.R. Nocchi and D.B. Silva et al., 2021. Involvement of muscarinic receptors in hypotensive and diuretic effects of aqueous soluble fraction from Asphodelus tenuifolius Cav. Evidence-Based Complementary Altern. Med., Vol. 2021. 10.1155/2021/6653270.
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  2. Chaudhry, M.A., Alamgeer, M.N. Mushtaq, I.A. Bukhari and A.M. Assiri, 2021. Ipomoea hederacea Jacq.: A plant with promising antihypertensive and cardio-protective effects. J. Ethnopharmacol., Vol. 268. 10.1016/j.jep.2020.113584.
    CrossRef  |  Direct Link  |  
  3. Bukhari, I.A., O.Y. Mohamed, A. Mahmood, A.A. Alfadda and A.A. Almotrefi, 2021. 1-trifluoromethoxyphenyl-3(1-propionylpiperidin-4-yl) urea (TPPU), a soluble epoxide hydrolase inhibitor attenuates high fat diet-induced cardiovascular and metabolic disorders in rats. Eur. Rev. Med. Pharmacol. Sci., 25: 3835-3847.
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  4. Asif, H., Alamgeer, I.A. Bukhari, F. Vohra, S. Afzal, S.W. Khan and Z.R. Niazi, 2021. Phytochemical analysis of crude extract of Delphinium brunonianum and its effect on hypertension and metabolic perturbations in fructose fed rats. Nat. Prod. Res., 35: 2982-2986.
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  5. Ameer, O.Z., I.M. Salman, A.Y. Alwadi, A. Ouban, F.M. Abu-Owaimer, S.D. AlSharari and I.A. Bukhari, 2021. Regional functional and structural abnormalities within the aorta as a potential driver of vascular disease in metabolic syndrome. Exp. Physiol., 106: 771-788.
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  6. Younis, W., Alamgeer, V.B. Schini-Kerth, D.B. da Silva, A.G. Junior, I.A. Bukhari and A.M. Assiri, 2020. Role of the NO/cGMP pathway and renin-angiotensin system in the hypotensive and diuretic effects of aqueous soluble fraction from Crataegus songarica K. Koch. J. Ethnopharmacol., Vol. 249. 10.1016/j.jep.2019.112400.
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  7. Vohra, F., I.A. Bukhari, S.A. Sheikh, R. Albaijan, M. Naseem and M. Hussain, 2020. Effectiveness of scaling and root planing with and without adjunct probiotic therapy in the treatment of chronic periodontitis among shamma users and non-users: A randomized controlled trial. J. Periodontol., 91: 1177-1185.
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  8. Vohra, F., I.A. Bukhari, S.A. Sheikh, R. Albaijan and M. Naseem, 2020. Comparison of self-rated oral symptoms and periodontal status among cigarette smokers and individuals using electronic nicotine delivery systems. J. Am. Coll. Health, 68: 788-793.
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  9. Qasim, S., Alamgeer, S. Kalsoom, M. Shahzad and H.M. Irfan et al., 2020. Appraisal of disease-modifying potential of amlodipine as an anti-arthritic agent: New indication for an old drug. Inflammopharmacology, 28: 1121-1136.
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  10. Meo, S.A., S.Z.A. Zaidi, T. Shang, J.Y. Zhang and T. Al-Khlaiwi et al., 2020. Biological, molecular and pharmacological characteristics of chloroquine, hydroxychloroquine, convalescent plasma, and remdesivir for COVID-19 pandemic: A comparative analysis. J. King Saud Univ. Sci., 32: 3159-3166.
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  11. Bukhari, I.A., S.S. Habib, A. Alnahedh, F. Almutairi, L. Alkahtani, L.A. Alareek and G.A. Assiri, 2020. Relationship of body adiposity with platelet function in obese and non-obese individuals. Cureus, Vol. 12. 10.7759/cureus.6815.
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  12. Bukhari, I.A., O.Y. Mohamed, A.A. Almotrefi, B.Y. Sheikh, O. Nayel, F. Vohra and S. Afzal, 2020. Cardioprotective effect of olive oil against ischemia reperfusion-induced cardiac arrhythmia in isolated diabetic rat heart. Cureus, Vol. 12. 10.7759/cureus.7095.
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  13. Bukhari, I.A., B.I. Alorainey, A.A. Al-Motrefi, A. Mahmoud, W.B. Campbell and B.D. Hammock, 2020. 1-trifluoromethoxyphenyl-3-(1-propionylpiperidin-4-yl) urea (TPPU), a soluble epoxide hydrolase inhibitor, lowers L-NAME-induced hypertension through suppression of angiotensin-converting enzyme in rats. Eur. Rev. Med. Pharmacol. Sci., 24: 8143-8150.
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  14. Uttra, A.M., Alamgeer, M. Shahzad, A. Shabbir, S. Jahan, I.A. Bukhari and A.M. Assiri, 2019. Ribes orientale: A novel therapeutic approach targeting rheumatoid arthritis with reference to pro-inflammatory cytokines, inflammatory enzymes and anti-inflammatory cytokines. J. Ethnopharmacol., 237: 92-107.
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  15. Saeed, A., A.M. Assiri, I.A. Bukhari and R. Assiri, 2019. Antifungals in a case of basidiobolomycosis: Role and limitations. BMJ Case Rep., Vol. 12. 10.1136/bcr-2019-230206.
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  16. Bukhari, I.A., A.H. Gilani, S.A. Meo and A. Saeed, 2016. Analgesic, anti-inflammatory and anti-platelet activities of Buddleja crispa. BMC Complement Altern Med., 10.1186/s12906-016-1021-4.
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  17. Shah, A.H., H.S. Khalil, F.A. Alshahrani, S.Q. Khan, N.R. AlQthani, I.A. Bukhari and M.Z. Kola, 2015. Knowledge of medical and dental practitioners towards dental management of patients on anticoagulant and/or anti-platelet therapy. Saudi J. Dental Res., 6: 91-97.
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  18. Almotrefi, A.A., I.A. Bukhari and M.S. Alhumayyd 2015. Investigation of the antifibrillatory drug interactions between Amiodarone and Ibutilide in isolated. Fundam. Clin. Pharmacol., 29: 553-557.
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  19. Alhumayyd, M.S., I.A. Bukhari and A.A. Almotrefi, 2014. Effect of piperine, a major component of black pepper, on the pharmacokinetics of domperidone in rats. J. Physiol. Pharmacol., 65: 785-789.
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  20. Meo, S.A., A.M. Usmani, M.S. Vohra and I.A. Bukhari, 2013. Impact of GDP, spending on R and D, number of universities and scientific journals on research publications in pharmacological sciences in Middle East. Eur Rev Med Pharmacol Sci. 17: 2697-2705.
    PubMed  |  Direct Link  |  
  21. Bukhari, I.A., M.S. Alhumayyd, A.L. Mahesar and A.H. Gilani, 2013. The analgesic and anticonvulsant effects of piperine in mice. J. Physiol.Pharmacol., 64: 789-794.
  22. Bukhari, I.A., A.J. Shah, R.A. Khan, S.A. Meo, A. Khan and A.H. Gilani, 2013. Gut modulator effects of conyza bonariensis explain its traditional use in constipation and diarrhea. Eur. Rev. Med.Pharmacol. Sci., 17: 552-558.
    PubMed  |  Direct Link  |  
  23. Bukhari, I.A., 2013. The central analgesic and anti-inflammatory activities of the methanolic extract of Carthamus oxycantha. J. Physiol. Pharmacol., 64: 369-375.
    PubMed  |  Direct Link  |  
  24. Bukhari, I.A. and A. Dar, 2013. Behavioral profile of Hypericum perforatum (St. John's Wort) extract. A comparison with standard antidepressants in animal models of depression. Eur. Rev. Med. Pharmacol. Sci., 17: 1082-1089.
    PubMed  |  Direct Link  |  
  25. Bukhari, I.A., A.J. Shah, K.M. Gauthier, K.A. Walsh and S.R. Koduru, 2012. 11,12,20-Trihydroxy-eicosa-8(Z)-enoic acid: a selective inhibitor of 11,12-EET-induced relaxations of bovine coronary and rat mesenteric arteries. Am. J. Physiol. Heart Circ. Physiol., 302: H1574-H1583.
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  26. Bukhari, I.A., K.M. Gauthier, S.G. Jagadeesh, B. Sangras, J.R. Falck and W.B. Campbell, 2011. 14,15-dihydroxy-eicosa-5(z)-enoic acid selectively inhibits 14,15-epoxyeicosatrienoic acid-induced relaxations in bovine coronary arteries. J. Pharmacol. Exp. Ther., 336: 47-55.
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  27. Bukhari, I.A., R.A. Khan, A.H. Gilani, S. Ahmed and S.A. Saeed, 2010. Analgesic, anti-inflammatory and anti-platelet activities of the methanolic extract of acacia modesta leaves. Inflammopharmacology, 18: 187-196.
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  28. Gilani, A.H., I.A. Bukhari, R.A. Khan, A.J. Shah, I. Ahmad and A. Malik, 2009. Presence of blood-pressure lowering and spasmolytic constituents in buddleja crispa. Phytother. Res., 23: 492-497.
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  29. Raza-ur, R., M.A. Ansari, Z. Hayder, A.A. Siddiqui, I.A. Bukharia and M.A. Qayyum, 2008. Double blind placebo controlled clinical trial examining the effectiveness of St. John's Wort (Hypericum perforatum) in mild to moderate depression. J. Pak. Psychiatric Soc., 5: 105-111.
  30. Ullah, F., H. Hussain, J. Hussain, I.A. Bukhari and M.T. Khan et al., 2007. Tyrosinase inhibitory pentacyclic triterpenes and analgesic and spasmolytic activities of methanol extracts of rhododendron collettianum. Phytother Res., 21: 1076-1081.
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  31. Bukhari, I.A., R.A. Khan, A.U. Gilani, A.J. Shah, J. Hussain and V.U. Ahmad, 2007. The analgesic, anti-inflammatory and calcium antagonist potential of tanacetum artemisioides. Arch. Pharm. Res., 30: 303-312.
    PubMed  |  Direct Link  |  
  32. Gilani, A.H., I.A. Bukhari, R.A. Khan, A.U. Khan, F.Ullah and V.U. Ahmad, 2005. Cholinomimetic and calcium channel blocking activities of carthamus oxycantha. Phytother. Res., 19: 679-683.
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  33. Ahmad, V.U., H. Hussain, I.A. Bukhari, J. Hussain, A.R. Jassbi and A. Dar, 2005. Antinociceptive diterpene from Euphorbia decipiens. Fitoterapia, 76: 230-232.
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  34. Bukhari, I.A., A. Dar and R.A. Khan, 2004. Antinociceptive activity of methanolic extracts of St. John's Wort (Hypericum perforatum) preparation. Pak. J. Pharm. Sci., 17: 13-19.
  35. Ahmad, V.U., H. Hussain, A.R. Jassbi, J. Hussain and I.A. Bukhari et al., 2003. New bioactive diterpene polyesters from Euphorbia decipiens. J. Nat. Prod., 66: 1221-1224.
    PubMed  |  Direct Link  |  
  36. Ahmad, V.U., H. Hussain, J. Hussain, A.R. Jassbi, I.A. Bukhari, 2002. New bioactive compounds from Euphorbia decipiens. Z-Naturforch, 57b: 1066-1071.