Dr. Mukul   Das
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Dr. Mukul Das

Chief Scientist
Indian Institute of Toxicology Research, India


Highest Degree
Ph.D. in Food and Nutrition from Kanpur University, India

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Biography

Dr. Mukul Das is currently working as Chief Scientist at Indian Institute of Toxicology Research, Lucknow, India. He obtained his Ph.D. in Food and Nutrition from same Institute. He also worked as Senior Research Fellow, Junior Research Fellow, Scientist C, Assistant Director, and Deputy Director at Industrial Toxicology Research Centre, Lucknow, India, Research Associate and Senior Research Associate at Case Western Reserve University and Veterans Administration Medical Centre, Cleveland, Ohio, USA. Dr. Mukul Das received honor includes Council of Scientific & Industrial Research (India) merit fellowship award, recipient of Burroughs Welcome Fund Fellowship Award in honor of Dr Marion Sulzberger, USA, recipient of Schering-Plough Foundation Research Fellowship Award from Dermatology Foundation, USA, recipient of ITRC Technology Award, awarded Fellow of National Academy of Agricultural Sciences (FNAASc), and Paper cited on Cover Page of Clinical & Exp Allergy, and many others. His research experience focused On Biochemistry and Biochemical Toxicology, Chemical Carcinogenesis and DNA Adduct Formation, Chemoprevention of Carcinogenesis, Xenobiotic Biotransformation With Reference To Toxication and Detoxifation Mechanisms, Neurotoxicity and Neurochemistry, Dermatotoxicology and Dermatophamacology, Prostaglandin Synthetase Dependent Xenobiotic Metabolism, Phototoxicology, Toxicity of Food Adulterants and Contaminants, Nanotoxicology. He supervised 24 research students for PhD dissertation from Lucknow University; Awadh University; Benaras Hindu University; Gorakhpur University and Jamia Hamdard University, and 12 students for MSc dissertation from various Universities. He is also serving as member of editorial board and referee for several journals. He is member of several societies such as American Association for Cancer Research, Society for Investigative Dermatology, USA, International Society for the Study of Xenobiotics, Indian Pharmacological Society, Indian Photobiology Society, and life member of Society of Biological Chemists, India, Society of Toxicology, India, Indian Pharmacological Society, Indian Association for Cancer Research, National Academy of Sciences, Indian Academy of Neurosciences, Association of Food Scientists and Technologists, India, U.P. Association for the Science & Technology Advancement, Environmental Mutagen Society of India, Alumni Association of Department of Biochemistry, Lucknow University, and president of Indian Nanoscience Society. He carried out number of research projects as Principal Investigator and Co-investigator. He has total 273 publications.

Area of Interest:

Pharmacology and Toxicology
100%
Biochemistry
62%
Biochemical Toxicology
90%
Chemical Carcinogenesis
75%
Chemoprevention
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
0
Abstracts
0

Selected Publications

  1. Tewari, P., R. Roy, S. Mishra, A. Yadav and B.P. Chaudhari et al., 2015. Benzanthrone induced immunotoxicity via oxidative stress and inflammatory mediators in female Balb/c mice Immunobiology, 220: 369-381.
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  2. Roy, R., M. Das and P.D. Dwivedi, 2015. Toxicological mode of action of ZnO nanoparticles: Impact on immune cells. Mol. Immunol., 63: 184-192.
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  3. Panigrahi, G.K., C.H. Ratnasekhar, M. Mudiam, V.M. Vashishtha, S. Raisuddin and M. Das, 2015. Activity guided chemo toxic profiling of Cassia occidentalis (CO) seeds: Detection of toxic compounds in body fluids of CO exposed patients and experimental rats. Chem. Res. Toxicol. .
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  4. Dixit, S., A. Yadav, P.D. Dwivedi and M. Das, 2015. Toxic hazards of leather industry and technologies to combat threat: A review. J. Cleaner Prod., 87: 39-49.
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  5. Alam, S., R.S. Yadav, A. Pal, S.K. Purshottam, B.P. Chaudhari, M. Das and K.M. Ansari, 2015. Dietary administration of Nexrutine inhibits rat liver tumorigenesis and induces apoptotic cell death in human hepatocellular carcinoma cells. Toxicol. Rep., 2: 1-11.
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  6. Verma, A.K., S. Kumar, B.P. Chaudhari, N. Tuteja, M. Das and P.D. Dwivedi, 2014. Allergenicity assessment of Genetically-modified tobacco expressing salt tolerance cbl gene. Plant Foods Hum. Nutr., 69: 209-215.
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  7. Verma, A.K., S. Kumar, A. Sharma, D. Kumar and R. Roy et al., 2014. Allergic manifestation by black gram (Vigna mungo) proteins in allergic patients, BALB/c mice and RBL-2H3 cells. Int. Immunopharmacol., 23: 92-103.
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  8. Sharma, A., S. Kumar, R.K. Gupta, R. Roy and K. Gupta et al., 2014. Elucidation of immediate type I reactions in native and GM mustard (Brassica sps.). Food Res. Int., 64: 810-821.
  9. Roy, R., V. Parashar, L.K.S. Chauhan, R. Shanker, M. Das, A. Tripathi and P.D. Dwivedi, 2014. Mechanism of uptake of ZnO nanoparticles and inflammatory responses in macrophages require PI3K mediated MAPKs signaling. Toxicol. In Vitro, 28: 457-467.
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  10. Roy, R., S.K. Singh, M. Das, A. Tripathi and P.D. Dwivedi, 2014. Toll‐like receptor 6 mediated inflammatory and functional responses of zinc oxide nanoparticles primed macrophages. Immunology, 142: 453-464.
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  11. Roy, R., S.K. Singh, L.K.S. Chauhan, M. Das, A. Tripathi and P.D. Dwivedi, 2014. Zinc oxide nanoparticles induce apoptosis by enhancement of autophagy via P13/Akt/mTOR inhibition. Toxicol. Lett., 227: 29-40.
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  12. Roy, R., S. Kumar, A.K. Verma, A. Sharma and B.P. Chaudhari et al., 2014. Zinc oxide nanoparticles provide an adjuvant effect to ovalbumin via a Th2 response in Balb/c mice. Int. Immunol., 26: 159-172.
  13. Roy, R., S. Kumar, A. Tripathi, M. Das and P.D. Dwivedi, 2014. Interactive threats of nanoparticles to the biological system. Immunol. Lett., 158: 79-87.
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  14. Roy, R., L.K.S. Chauhan, M. Das, A. Tripathi and P.D. Dwivedi, 2014. Phagocytic cells internalize ZnO particles by FcγII/III-receptor pathway. Immunobiology, 219: 746-755.
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  15. Roy, R., D. Kumar, A. Sharma, P. Gupta and B.P. Chaudhari et al., 2014. ZnO nanoparticles induced adjuvant effect via toll-like receptors and Src signaling in Balb/c mice. Toxicol. Lett., 230: 421-433.
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  16. Rastogi, S.D., S. Dixit, A. Tripathi and M. Das, 2014. Simultaneous determination of acetaminophen and the color excipient by derivatized spectroscopy in syrup formulations: Exposure risk of colors to children. AAPS Pharm. Sci. Tech. (In press). .
  17. Panigrahi, G.K., A. Yadav, A. Yadav, K.M. Ansari and R.K. Chaturvedi et al., 2014. Hepatic transcriptional analysis in rats treated with Cassia occidentalis seed: Involvement of oxidative stress and impairment in xenobiotic metabolism as a putative mechanism of toxicity. Toxicol. Lett., 229: 273-283.
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  18. Panigrahi, G., S. Tiwari, K.M. Ansari, R.K. Chaturvedi and V.K. Khanna et al., 2014. Association between children death and consumption of Cassia occidentalis seeds: Clinical and experimental investigations. Food Chem. Toxicol., 67: 236-248.
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  19. Mishra, V., K.M. Ansari, B.P. Chaudhuri, R. Khanna and M. Das, 2014. Argemone oil and butter yellow induced toxicity in hepatic and extrahepatic tissues of mice. Bioenergetics, Vol. 3. .
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  20. Mishra, S., S. Dixit, P.D. Dwivedi, H.P. Pandey and M. Das, 2014. Influence of temperature and pH on degradation of deoxynivalenol (DON) in aqueous medium: Comparative cytotoxicity of DON and degraded product. Food Addit. Contam., 31: 121-131.
  21. Mishra, S., P.D. Dwivedi, H.P. Pandey and M. Das, 2014. Role of oxidative stress in Deoxynivalenol induced toxicity. Food Chem. Toxicol., 72: 20-29.
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  22. Mishra, S., A. Tripathi, B.P. Chaudhari, P.D. Dwivedi, H.P. Pandey and M. Das, 2014. Deoxynivalenol induced mouse skin cell proliferation and inflammation via MAPK pathway. Toxicol. Applied Pharmacol., 279: 186-197.
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  23. Mishra, M., S. Ali and M. Das, 2014. Analysis of oxytocin in milk samples and intake pattern in different age groups of Indian population. Toxicol. Mechan. Methods, 24: 342-346.
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  24. Maurya, H.K., S.K. Gautam, R. Pratap, V.K. Tandon and A. Kumar et al., 2014. Regioselective synthesis of polycyclic aza-oxa and aza-oxa-thia heteroarenes as Colo-205 and HepG2 carcinoma cells growth inhibitors. Eur. J. Med. Chem., 81: 367-377.
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  25. Kumar, S., A.K. Verma, A. Sharma, R. Roy and D. Kumar et al., 2014. Phaseolin: A 47.5 kDa protein of red kidney bean (Phaseolus vulgaris L.) plays a pivotal role in hypersensitivity induction. Int. Immunopharmacol., 19: 178-190.
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  26. Kumar, S., A. Sharma, M. Das, S.K. Jain and P.D. Dwivedi, 2014. Leucoagglutinating phytohemagglutinin: Purification, characterization, proteolytic digestion and assessment for allergenicity potential in BALB/c mice. Immunopharmacol. Immunotoxicol., 36: 138-144.
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  27. Kumar, S., A. Sharma, G. Singh, A.K. Verma and R. Roy et al., 2014. Allergenic responses of green gram (Vigna radiate L. Millsp) proteins can be vitiated by induction of oral tolerance due to single acute dose in BALB/c mice. Food Res. Int., 57: 130-141.
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  28. Kumar, S., A. Misra, A.K. Verma, A. Sharma, M. Das and P.D. Dwivedi, 2014. Red GRAM (Cajanus cajan) proteins induce hypersensitivity in BALB/c mice following oral exposure and cause mediators release from RBL-2H3 cells. Inflamm. Allergy Drug Targets, (In Press). .
  29. Kumar, D., S. Kumar, A.K. Verma, A. Sharma and A. Tripathi et al., 2014. Hypersensitivity linked to exposure of broad bean protein (s) in allergic patients and BALB/c mice. Nutrition, 30: 903-914.
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  30. John, T.J. and M. Das, 2014. Acute encephalitis syndrome in children in Muzaffarpur: Hypothesis of toxic origin. Curr. Sci., 106: 1184-1185.
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  31. Gupta, K., S. Kumar, M. Das and P.D. Dwivedi, 2014. Peptide based immunotherapy: A pivotal tool for allergy treatment. Int. Immunopharmacol., 19: 391-398.
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  32. Alam, S., A. Pal, R. Kumar, P.D. Dwivedi, M. Das and K.M. Ansari, 2014. EGFR‐mediated Akt and MAPKs signal pathways play a crucial role in patulin‐induced cell proliferation in primary murine keratinocytes via modulation of Cyclin D1 and COX‐2 expression. Mol. Carcinogenesis, 53: 988-998.
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  33. Yadav, A., A. Kumar, A. Tripathi and M. Das, 2013. Sunset yellow FCF, a permitted food dye, alters functional responses of splenocytes at non-cytotoxic dose. Toxicol. Lett., 217: 197-204.
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  34. Verma, A.K., S. Kumar, M. Das and P.D. Dwivedi, 2013. A comprehensive review of legume allergy. Clin. Rev. Allergy Immunol., 45: 30-46.
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  35. Pal, A., S. Alam, J. Singhal, R. Kumar, K.M. Ansari and M. Das, 2013. Protective effect of topical application of α-tocopherol and/or N-acetyl cysteine on argemone oil/alkaloid induced skin tumorigenesis in mice. Nutr. Cancer, 65: 78-87.
  36. Mishra, S., K.M. Ansari, H.P. Pandey, P.D. Dwivedi and M. Das, 2013. Surveillance of deoxynivalenol in cereals and its likely intake in Indian population. Food Control, 30: 549-555.
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  37. Mishra, M., V. Mishra, B.P. Chaudhuri, V.K. Khanna, S. Mehrotra, S. Ali and M. Das, 2013. Anomalies in ovary following oral exposure to oxytocin: Mechanistic studies. Reprod. Toxicol., 40: 24-34.
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  38. Mishra, M., S. Ali and M. Das, 2013. A new extraction method for the determination of oxytocin in milk by enzyme immune assay or high-performance liquid chromatography: Validation by liquid chromatography-mass spectrometry. Food Anal. Methods, 6: 1308-1319.
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  39. Kumar, S., P.D. Dwivedi, M. Das and A. Tripathi, 2013. Macrophages in food allergy: An enigma. Mol. Immunol., 56: 612-618.
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  40. Kumar, S., K. Gupta, M. Das and P.D. Dwivedi, 2013. The recent advancements in therapeutics of food allergy. Recent Pat Food Nutr. Agric., 5: 188-200.
  41. Kumar, S., A.K. Verma, M. Das, S.K. Jain and P.D. Dwivedi, 2013. Clinical complications of kidney bean (Phaseolus vulgaris L.) consumption. Nutrition, 29: 821-827.
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  42. Kumar, S., A.K. Verma, M. Das and P.D. Dwivedi, 2013. A molecular insight of CTL-4 in food allergy. Immunol. Lett., 149: 101-109.
  43. Kumar, S., A.K. Verma, A. Sharma, D. Kumar and A. Tripathi et al., 2013. Phytohemagglutinins augment red kidney bean (Phaseolus vulgaris L.) induced allergic manifestations. J. Proteomics, 93: 50-64.
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  44. Kumar, S., A. Sharma, A.K. Verma, B.P. Chaudhari, M. Das, S.K. Jain and P.D. Dwivedi, 2013. Allergenicity potential of red kidney bean (Phaseolus vulgaris L.) proteins in orally treated BALB/c mice and passively sensitized RBL-2H3 cells. Cell. Immunol., 284: 37-44.
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  45. Kumar, R., S. Alam, B.P. Chaudhari, P.D. Dwivedi, S.K. Jain, K.M. Ansari and M. Das, 2013. Ochratoxin A-induced cell proliferation and tumor promotion in mouse skin by activating the expression of cyclin-D1 and cyclooxygenase-2 through nuclear factor-kappa B and activator protein-1. Carcinogenesis, 34: 647-657.
  46. Dwivedi, N., S. Kumar, K.M. Ansari, S.K. Khanna and M. Das, 2013. Skin tumorigenic potential of benzanthrone: Prevention by ascorbic acid. Food Chem. Toxicol., 59: 687-695.
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  47. Dixit, S., S.K. Khanna and M. Das, 2013. All India survey for analyses of colors in sweets and savories: Exposure risk in Indian population. J. Food Sci., 78: T642-T647.
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  48. Yadav, A., A. Kumar, P.D. Dwivedi, A. Tripathi and M. Das, 2012. In vitro studies on immunotoxic potential of orange II in splenocytes. Toxicol. Lett., 208: 239-245.
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  49. Verma, A.K., S. Kumar, M. Das and P.D. Dwivedi, 2012. Impact of thermal processing on legume allergens. Plant Foods Hum. Nutr., 67: 430-441.
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  50. Verma, A.K., S. Kumar, A. Tripathi, B.P. Chaudhari, M. Das and P.D. Dwivedi, 2012. Chickpea (Cicer arietinum) proteins induce allergic responses in nasobronchial allergic patients and BALB/c mice. Toxicol. Lett., 210: 24-33.
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  51. Misra, A., S. Kumar, A.K. Verma, N.P. Chanana, M. Das, V. Dhawan and P.D. Dwivedi, 2012. Safety evaluation of genetically modified mustard (V4) seeds in terms of allergenicity: Comparison with native crop. GM Crops Food, 3: 273-282.
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  52. Mishra, V., M. Mishra, K.M. Ansari, B.P. Chaudhari, R. Khanna and M. Das, 2012. Edible oil adulterants, argemone oil and butter yellow, as etiological agents for gall bladder cancer. Eur. J. Cancer, 48: 2075-2085.
  53. Kumar, S., A.K. Verma, M. Das and P.D. Dwivedi, 2012. Molecular mechanisms of IgE mediated food allergy. Int. Immunopharmacol., 13: 432-439.
  54. Kumar, S., A. Verma, M. Das and P.D. Dwivedi, 2012. Allergenic diversity among plant and animal food and their allergenicity. Food Rev. Int., 28: 277-298.
  55. Kumar, R., M. Das and K.M. Ansari, 2012. Nexrutine® induces apoptotic cell death in human squamous carcinoma 431 and human melanoma A375 cells and inhibits tumorigenesis in mouse skin. Carcinogenesis, 33: 1897-1908.
  56. Dixit, S., P.D. Dwivedi and M. Das, 2012. Simultaneous determination of sudan dyes along with dimethyl yellow in Indian curry samples by reverse phase liquid chromatography. J. Chromatogr. Sep. Tech., Vol. 3. 10.4172/2157-7064.1000150.
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  57. Dixit, S. and M. Das, 2012. Analysis of trans-fatty acids in edible oils and fats from Indian markets. J. Food Sci., 77: T118-T199.
  58. Mishra, V., K.M. Ansari, R. Khanna and M. Das, 2012. Role of ErbB2 mediated AKT and MAPK pathways in proliferation of primary cells of gall bladder induced by argemone oil and butter yellow. Cell Biol. Toxicol., 28: 149-159.
  59. Kumar, R., K.M. Ansari, N. Saxena, P.D. Dwivedi, S.K. Jain and M. Das, 2012. Risk assessment of ochratoxin A through wheat consumption in Indian populattion. Food Control, 26: 63-67.
  60. Verma, A.K., A. Misra, S. Subash, M. Das and P.D. Dwivedi, 2011. Computational allergenicity prediction of transgenic proteins expressed in genetically modified crops. Immunopharmacol. Immunotoxicol., 33: 410-422.
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  61. Shukla, K.K., A.A. Mahdi, V. Mishra, S. Rajender, S.N. Sankhwar, D. Patel and M. Das, 2011. Withania somnifera improves semen quality by combating oxidative stress and cell death and improving essential metal concentrations. Reprod. Biomed. Online, 22: 421-427.
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  62. Saxena, N., K.M. Ansari, R. Kumar, B.P. Chaudhari, P.D. Dwivedi and M. Das, 2011. Role of mitogen activated protein kinases in skin tumorigenicity of patulin. Toxicol. Applied Pharmacol., 257: 264-271.
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  63. Misra, A., R. Kumar, V. Mishra, B.P. Chaudhari, S. Raisuddin, M. Das and P.D. Dwivedi, 2011. Potential allergens of green gram (Vigna radiate L. Millsp) identified as members of cupin superfamily and seed albumin. Clin. Exp. Allergy, 41: 1157-1168.
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  64. Kumar, S., A.K. Verma, A. Misra, A. Tripathi and B.P. Chaudhari et al., 2011. Allergenic responses of red kidney bean (Phaseolus vulgaris cv chitra) polypeptides in BALB/c mice recognized by bronchial asthma and allergic rhinitis patients. Food Res. Int., 44: 2868-2879.
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  65. Kumar, S., A. Misra, A.K. Verma, R. Roy and A. Tripathi et al., 2011. Bt brinjal in India: A long way to go. GM Crops, 2: 92-98.
    CrossRef  |  PubMed  |  
  66. Kumar, R., P.D. Dwivedi, A. Dhawan, M. Das and K.M. Ansari, 2011. Citrinin-generated reactive oxygen species cause cell cycle arrest leading to apoptosis via the intrinsic mitochondrial pathway in mouse skin. Toxicol. Sci., 122: 557-566.
  67. Dixit, S., S.K. Purshottam, S.K. Khanna and M. Das, 2011. Usage pattern of synthetic food colours in different states of India and exposure assessment through commodities preferentially consumed by children. Food Addit. Contam.: Part A, 28: 996-1005.
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  68. Dixit, S., S.K. Khanna and M. Das, 2011. A simple method for simultaneous determination of basic dyes encountered in food preparations by reversed-phase HPLC. J. Assoc. Anal. Chem. Int., 94: 1874-1881.
    PubMed  |  
  69. Dhawan, A., R. Shanker, M. Das and K.C. Gupta, 2011. Guidance for safe handling of nanomaterials. J. Biomed. Nanotechnol., 7: 218-224.
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  70. Das, M., 2011. Toxicology and environmental safety of chemicals used in leather industry. J. Indian Leather Tech Assoc., 61: 500-514.
  71. Tripathi, M., S. Dixit, S.K. Khanna and M. Das, 2010. Intake pattern of synthetic colours by different age and socio-economic consumer groups of Lucknow, India. Int. J. Food Nutr. Public Health, 3: 1-19.
  72. Misra, A., R. Kumar, V. Mishra, B.P. Chaudhari, A. Tripathi, M. Das and P.D. Dwivedi, 2010. Partial characterization of red gram (Cajanus cajan L. Millsp) polypeptides recognized by patients exhibiting rhinitis and bronchial asthma. Food Chem. Toxicol., 48: 2725-2736.
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  73. Dixit, S., S.K. Purshottam, S.K. Gupta, S.K. Khanna and M. Das, 2010. Usage pattern and exposure assessment of food colours in different age groups of consumers in the State of Uttar Pradesh, India. Food Addit. Contam., 27: 181-189.
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  74. Dixit, S., S.K. Khanna and M. Das, 2010. Simultaneous determination of eight synthetic permitted and five commonly encountered non-permitted food colors in various food matrices by reversed-phase high- performance liquid chromatography. J. Assoc. Anal. Chem. Int., 93: 1503-1514.
  75. Babu, C.K., K.M. Ansari, S. Mehrotra, S. Patel, M. Dikshit and M. Das, 2010. Activation of inflammatory response and apoptosis of polymorphonuclear leukocytes in patients with argemone oil poisoning. Chem.-Biol. Interact., 183: 154-164.
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  76. Ansari, K.M. and M. Das, 2010. Skin tumor promotion by argemone oil/alkaloid in mice: Evidence for enhanced cell proliferation, ornithine decarboxylase, cyclooxygenase-2 and activation of MAPK/NF-κB pathway. Food Chem. Toxicol., 48: 132-138.
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  77. Ansari, K.M. and M. Das, 2010. Potentiation of tumour promotion by topical application of argemone oil/isolated sanguinarine alkaloid in a model of mouse skin carcinogenesis. Chem.-Biol. Interact., 188: 591-597.
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  78. Sharma, V., R.K. Shukla, N. Saxena, D. Parmar, M. Dasb and A. Dhawan, 2009. DNA damaging potential of zinc oxide nanoparticles in human epidermal cells. Toxicol. Lett., 185: 211-218.
    PubMed  |  
  79. Saxena, N., K.M. Ansari, R. Kumar, A. Dhawan, P.D. Dwivedi and M. Das, 2009. Patulin causes DNA damage leading to cell cycle arrest and apoptosis through modulation of Bax, p 53 and p 21/WAF1 proteins in skin of mice. Toxicol. Applied Pharmacol., 234: 192-201.
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  80. Misra, A., R. Prasad, M. Das and P.D. Dwivedi, 2009. Probing novel allergenic proteins of commonly consumed legumes. Immunopharmacol. Immunotoxicol., 31: 186-194.
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  81. Mishra, V., D.K. Saxena and M. Das, 2009. Effect of argemone oil and argemone alkaloid, sanguinarine on Sertoli-germ cell coculture. Toxicol. Lett., 186: 104-110.
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  82. Mishra, G., R. Shukla, M. Hasan, S.K. Khanna and M. Das, 2009. Potentiation of neurotoxicity of Lathyrus sativus by manganese: Alterations in blood-brain barrier permeability. Toxicol. Mech. Methods, 19: 318-326.
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  83. Eruvaram, N.R. and M. Das, 2009. Phenotype of hepatic xenobiotic metabolizing enzymes and CYP450 isoforms of sanguinarine treated rats: Effect of P450 inducers on its toxicity. Toxicol. Mech. Methods, 19: 510-517.
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  84. Dixit, S., S. Purshottam, S.K. Khanna and M. Das, 2009. Surveillance on quality of turmeric powders vis a vis curcumin content and presence of extraneous color s from city markets of India. Food Addit. Contam., 26: 1227-1231.
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  85. Saxena, N., P.D. Dwivedi, K.M. Ansari and M. Das, 2008. Patulin in apple juices: Incidence and likely intake in an Indian population. Food Addit. Contaminants, 1: 140-146.
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  86. Reddy, N.P. and M. Das, 2008. Interaction of sanguinarine alkaloid, isolated from argemone oil, with hepatic cytochrome p450 in rats. Toxicol. Mech. Methods, 18: 635-643.
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  87. Misra, A., R. Prasad, M. Das and P.D. Dwivedi, 2008. Prevalence of legume sensitization in patients of naso-bronchial allergy. Immunopharmacol. Immunotoxicol., 30: 529-542.
  88. Dixit, S., S.K. Khanna and M. Das, 2008. Non-uniform implementation of ban on Lathyrus cultivation in Indian states leading to unwarranted exposure of consumers. Curr. Sci., 94: 570-572.
  89. Dixit, S., S.K. Khanna and M. Das, 2008. Desirability to prescribe quality specifications for aluminium foils used as food contact material. Toxicol. Int., 15: 27-31.
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  90. Dixit, S., S.K. Khanna and M. Das, 2008. A simple 2-directional high-performance thin-layer chromatographic method for the simultaneous determination of curcumin, metanil yellow and sudan dyes in turmeric, chili and curry powders. J. Assoc. Anal. Chem. Int., 91: 1387-1396.
    PubMed  |  
  91. Dixit, S., K.K. Mishra, S.K. Khanna and M. Das, 2008. Beiizoate and synthetic color risk assessment of fast food sauces served at street food joints of Lucknow, India. Am. J. Food Technol., 3: 183-191.
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  92. Das, M., N. Saxena and P.D. Dwivedi, 2008. Emerging trends of nanoparticles application in food technology: Safety paradigms. Nanotoxicology, 3: 10-18.
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  93. Babu, C.K., S.K. Khanna and M. Das, 2008. Antioxidant status of erythrocytes and their response to oxidative challenge in humans with argemone oil poisoning. Toxicol. Applied Pharmacol., 230: 304-311.
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  94. Babu, C.K., K.M. Ansari, S. Mehrotra, R. Khanna, S.K. Khanna and M. Das, 2008. Alterations in redox potential of glutathione/glutathione disulfide and cysteine/cysteine disulfide couples in plasma of dropsy patients with argemone oil poisoning. Food Chem. Toxicol., 46: 2409-2414.
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  95. Tripathi, M., S.K. Khanna and M. Das, 2007. Surveillance on use of synthetic colours in eatables vis a vis prevention of food adulteration act of India. Food Control, 18: 211-219.
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  96. Rastogi, S., Y. Shukla, B.N. Paul, D.K. Chaudhury, S.K. Khanna and M. Das, 2007. Studies on mechanism of protective effect of Ocimum sanctum on 3-methylcholantherene, 7,12-dimethyl-benzanthracene and aflatoxin B1 induced skin carcinogenesis in mice. Toxicol. Applied Pharmacol., 224: 228-240.
  97. Mishra, K.K., S. Dixit, S.K. Purshottam, R.C. Pandey, M. Das and S.K. Khanna, 2007. Exposure assessment to Sudan dyes through consumption of artificially coloured chilli powders in India. Int. J. Food Sci. Technol., 42: 1363-1366.
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  98. Babu, C.K., S.K. Khanna and M. Das, 2007. Adulteration of mustard cooking oil with argemone oil: Do Indian food regulatory policies and antioxidant therapy both need revisitation? Antioxidants Redox Signaling, 9: 515-525.
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  99. Tripathi, M., S.K. Khanna and M. Das, 2006. Usage of saccharin in food products and its intake by the population of Lucknow, India. Food Addit. Contam., 23: 1265-1275.
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  100. Rastogi, S., R.K.S. Dogra, S.K. Khanna and M. Das, 2006. Skin tumorigenic potential of aflatoxin B1 in mice. Food Chem. Toxicol., 44: 670-677.
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  101. Pandey, M.K., S. Yadav, D. Parmar and M. Das, 2006. Induction of hepatic cytochrome P450 isozymes, benzo (a) pyrene metabolism and DNA binding following exposure to polycyclic aromatic hydrocarbon residues generated during repeated fish fried oil in rats. Toxicol. Applied Pharmacol., 213: 126-134.
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  102. Pandey, M.K., A.B. Pant and M. Das, 2006. In vitro cytotoxicity of polycyclic aromatic hydrocarbon residues arising through repeated fish fried oil in human hepatoma Hep G2 cell line. Toxicol. in vitro, 20: 308-316.
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  103. Pandey, M.K., A. Dhawan and M. Das, 2006. Induction of P53, P21Waf1, orinithine decorboxylase activity and DNA damage leading to cell‐cycle arrest and apoptosis following topical application of repeated fish fried oil extract to mice. Mol. Carcinogenesis, 45: 805-813.
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  104. Pandey, M.K. and M. Das, 2006. Assessment of carcinogenic potential of repeated fish fried oil in mice. Mol. Carcinogenesis, 45: 741-751.
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  105. Babu, C.K., S.K. Khanna and M. Das, 2006. Safety evaluation studies on argemone oil through dietary exposure for 90days in rats. Food Chem. Toxicol., 44: 1151-1157.
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  106. Ansari, K.M., A. Dhawan, S.K. Khanna and M. Das, 2006. Protective effect of bioantioxidants on argemone oil/sanguinarine alkaloid induced genotoxicity in mice. Cancer Lett., 244: 109-118.
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  107. Rastogi, R.P., P. Chand, M.K. Pandey and M. Das, 2005. Dual control mechanism in a Belousov-Zhabotinskii (BZ) oscillator with glucose and oxalic acid as a double substrate. J. Phys. Chem. A, 109: 4562-4567.
  108. Das, M., S. Dixit and S.K. Khanna, 2005. Justifying the need to prescribe limits for toxic metal contaminants in food-grade silver foils. Food Additives Contaminants, 22: 1219-1223.
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  109. Das, M., K.M. Ansari, A. Dhawan, Y. Shukla and S.K. Khanna, 2005. Correlation of DNA damage in epidemic dropsy patients to carcinogenic potential of argemone oil and isolated sanguinarine alkaloid in mice. Int. J. Cancer, 117: 709-717.
    CrossRef  |  Direct Link  |  
  110. Das, M., K. Babu, N.P. Reddy and L.M. Srivastava, 2005. Oxidative damage of plasma proteins and lipids in epidemic dropsy patients: Alterations in antioxidant status. Biochim. Biophys. Acta-General Subj., 1722: 209-217.
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  111. Das, M. and S.K. Khanna, 2005. Scope for formulating quality standards of food grade silver. Curr. Sci. Bangalore, 89: 1307-1308.
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  112. Ansari, K.M., A. Dhawan, S.K. Khanna and M. Das, 2005. In vivo DNA damaging potential of sanguinarine alkaloid, isolated from argemone oil, using alkaline Comet assay in mice. Food Chem. Toxicol., 43: 147-153.
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  113. Tripathi, M., S.K. Khanna and M. Das, 2004. A novel method for the determination of synthetic colors in ice cream samples. J. AOAC Int., 87: 657-663.
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  114. Singh, R.P., R. Khanna, S.K. Khanna and M. Das, 2004. Enhancement of urinary elimination of 3-bromobenzanthrone metabolites by oral supplementation of ascorbic acid in Guinea Pigs. Biomed. Environ. Sci., 17: 390-396.
    PubMed  |  Direct Link  |  
  115. Singh, R.P., R. Khanna, S.K. Khanna and M. Das, 2004. Bio-elimination of conjugated metabolites of 3-bromobenzanthrone in Urine of Rats and Guinea Pigs. Toxicol. Mech. Methods, 14: 345-354.
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  116. Rastogi, S., D.D. Premendra, K.K. Subhash and D. Mukul, 2004. Detection of aflatoxin M1 contamination in milk and infant milk products from Indian markets by ELISA. Food Control, 15: 287-290.
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  117. Pandey, M.K., K.K. Mishra, S.K. Khanna and M. Das, 2004. Detection of polycyclic aromatic hydrocarbons in commonly consumed edible oils and their likely intake in the Indian population. J. Am. Oil Chem. Soc., 81: 1131-1136.
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  118. Dwivedi, P.D., M. Das and S.K. Khanna, 2004. Need for upgrading food quality monitoring capacities in the new globalized market scenario. Curr. Sci., 87: 729-730.
  119. Dixit, S. and M. Das, 2004. Colourful holi: Use of natural versus synthetic colours. Envis Newslett., 11: 9-11.
  120. Das, M., S. Rastogi and S.K. Khanna, 2004. Mechanism to study 1: 1 stoichiometry of NADPH and alkoxyphenoxazones metabolism spectrophotometrically in subcellular biological preparations. Biochim. Biophys. Acta (BBA)-General Subj., 1675: 1-11.
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  121. Ansari, K.M., L.K. Chauhan, A. Dhawan, S.K. Khanna and M. Das, 2004. Unequivocal evidence of genotoxic potential of argemone oil in mice. Int. J. Cancer, 112: 890-895.
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  122. Singh, R.P., R. Khanna, J.L. Kaw, S.K. Khanna and M. Das, 2003. Comparative effect of benzanthrone and 3-bromobenzanthrone on hepatic xenobiotic metabolism and anti-oxidative defense system in guinea pigs. Arch. Toxicol., 77: 94-99.
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  123. Kumar, M., A. Kannan, R.K. Upreti, G. Mishra, S.K. Khanna and M. Das, 2003. Toxic interaction of Lathyrus sativus and manganese in guinea pig intestine. Toxicol. Mech. Methods, 13: 295-300.
    Direct Link  |  
  124. Singh, R.P., R. Khanna, S.K. Khanna and M. Das, 2002. A sensitive method of monitoring exposure to 3-bromobenzanthrone in industrial dyestuff workers. Toxicol. Mech. Methods, 12: 229-237.
    Direct Link  |  
  125. Singh, R.P., M. Das, R. Khanna and S.K. Khanna, 2002. Effect of topical application of 3-bromobenzanthrone on hepatic lipid peroxidation and bio-antioxidants: Comparison with benzanthrone. Indian J. Toxicol., 9: 107-111.
  126. Rastogi, S., S.K. Khanna and M. Das, 2002. A spectrophotometric method to monitor the catalytic activity of microsomal cytochrome P-450 IIB 1/2: Comparison with fluorometric assay. Indian J. Biochem. Biophys., 39: 191-196.
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  127. Rastogi, S., M. Das and S. Khanna, 2002. A novel approach to study the kinetics of electron donor, substrate and product independently and simultaneously for pentoxyresorufin-O-deethylase activity. FEBS Lett., 512: 121-124.
    PubMed  |  
  128. Rastogi, R.P., M.M. Husain, P. Chand, G. Misra and M. Das, 2002. Anomalous control mechanism in a B-Z type oscillator involving only fructose as organic substrate. Chem. Phys. Lett., 353: 40-48.
  129. Pandey, M. and M. Das, 2002. Khadya telo mai polycyclic aromatic hydrocarbon Bhartiya peripechya mai. Vish Vigyan Sandesh, 8: 19-20.
  130. Mukhopadhyay, I., A. Nazir, K. Mahmood, D.K. Saxena, M. Das, S.K. Khanna and D.K. Chowdhuri, 2002. Toxicity of argemone oil: Effect on hsp70expression and tissue damage in transgenic Drosophila melanogaster (hsp70-lacZ) Bg 9. Cell Biol. Toxicol., 18: 1-11.
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  131. Khanna, R.N., M. Das and M. Anand, 2002. Influence of phenobarbital and carbon tetrachloride on modulation of tissue retention profile of hexachlorocyclohexane in rats. Biomed. Environ. Sci., 15: 119-129.
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  132. Amba, A., M. Kumar, R.K. Upreti, S.K. Khanna and M. Das, 2002. Effect of dietary administration of Lathyrus sativus pulse on intestinal biochemical parameters in normal and scorbutic guinea pigs. Biomed. Environ. Sci., 15: 315-322.
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  133. Amba, A., K. Seth, M. Ali, M. Das, A.K. Agarwal, S.K. Khanna and P.K. Seth, 2002. Comparative effect of dietary administration of Lathyrus sativus pulse on behaviour, neurotransmitter receptors and membrane permeability in rats and guinea pigs. J. Applied Toxicol., 22: 415-421.
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  134. Rastogi, S., M. Das and S.K. Khanna, 2001. Quantitative determination of aflatoxin B1-oxime by column liquid chromatography with ultraviolet detection. J. Chromatogr. A, 933: 91-97.
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  135. Kannan, A., M. Das and S.K. Khanna, 2001. Analysis of menthol content in Pan masala samples collected from the State of Uttar Pradesh. J. Food Sci. Technol., 38: 339-342.
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  136. Dwivedi, N., M. Das and S.K. Khanna, 2001. Role of biological antioxidants in benzanthrone toxicity. Arch. Toxicol., 75: 221-226.
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  137. Singh, R.P., M. Das, R. Khanna and S.K. Khanna, 2000. Evaluation of dermal irritancy potential of benzanthrone-derived dye analogs: Structure activity relationship. Skin Pharmacol. Applied Skin Physiol., 13: 165-173.
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  138. Rastogi, R.P., M.M. Husain, P. Chand and M. Das, 2000. BZ oscillator with fructose and tartaric acid as organic substrates. Indian J. Chem. Sect. A, 39: 679-684.
    Direct Link  |  
  139. Dwivedi, P.D., A. Misra, R. Shanker and M. Das, 2000. Are nanomaterials a threat to the immune system? Nanotoxicology, 3: 19-26.
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  140. Das, M. and S.K. Khanna, 2000. Sankramak jalodar (Dropsy). Vish Vigyan Sandesh, 6: 15-16.