Dr. Namasivayam Elangovan
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Dr. Namasivayam Elangovan

Assistant Professor
Periyar University, India

Highest Degree
Ph.D. in Medical Sciences from University of Madras, India

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Area of Interest:

Biomedical Sciences
100%
Biotechnology
62%
Nanomedicine
90%
Neuroscience
75%
Toxicology
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
0
Abstracts
0

Selected Publications

  1. Manimaran, D., S. Ghanendra, M. Sridhar, J. Kaliaperumal and S. Muniyaraj et al., 2019. Molecular insights of newly identified potential peptide inhibitors of hypoxia inducible factor 1α causing breast cancer. J. Mol. Struct., 1177: 558-563.
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  2. Manimaran, D., K. Nadhiya, T. Mohankumar, K. Manigandan and N. Elangovan, 2019. Erythrosine induces teratogenic effects via activation of ROS biogenesis in zebrafish embryos. Iran. J. Sci. Technol. Trans. A: Sci., 43: 763-771.
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  3. Johnravindar, D., N. Elangovan, N.O. Gopal, A. Muthaiyan and Q. Fei, 2019. Biobutanol production from cassava waste residue using Clostridium sp. AS3 in batch culture fermentation. Biofuels, (In Press). 10.1080/17597269.2019.1608671.
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  4. Thandapani, K., M. Kathiravan, E. Namasivayam, I.A. Padiksan and G. Natesan et al., 2018. Enhanced larvicidal, antibacterial, and photocatalytic efficacy of TiO2 nanohybrids green synthesized using the aqueous leaf extract of Parthenium hysterophorus. Environ. Sci. Pollut. Res., 25: 10328-10339.
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  5. Singh, V., M.M. Essa, N. Guizani, R. Balakrishnan and T. Hemalath et al., 2018. Protective effect of Zizyphus spinachristi on MPP+-induced oxidative stress. Front. Biosci., 10: 285-299.
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  6. Manimaran, D., A.S. Sulthana and N. Elangovan, 2018. Reactive black 5 induced developmental defects via potentiating apoptotic cell death in Zebrafish (Danio rerio) embryos. Pharm. Pharmacol. Int. J., 6: 449-452.
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  7. Dhanraj, V., J. Karuppaiah, R. Balakrishnan and N. Elangovan, 2018. Myricetin attenuates neurodegeneration and cognitive impairment in Parkinsonism. Front. Biosci., 10: 481-494.
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  8. Balakrishnan, R., N. Elangovan, T. Mohankumar, J. Nataraj and T. Manivasagam et al., 2018. Isolongifolene attenuates rotenone-induced mitochondrial dysfunction, oxidative stress and apoptosis. Front. Biosci., 10: 248-261.
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  9. Balakrishnan, R., K. Tamilselvam, A. Sulthana, T. Mohankumar, D. Manimaran and N. Elangovan, 2018. Isolongifolene attenuates oxidative stress and behavioral impairment in rotenone-induced rat model of Parkinson's disease. Int. J. Nutr. Pharmacol. Neurol. Dis., 8: 53-58.
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  10. Karthik, C., N. Elangovan, T.S. Kumar, S. Govindharaju, S. Barathi, M. Oves and P.I. Arulselvi, 2017. Characterization of multifarious plant growth promoting traits of rhizobacterial strain AR6 under chromium (VI) stress. Microbiol. Res., 204: 65-71.
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  11. Johnravindar, D., K. Murugesan, J.W. Wong and N. Elangovan, 2017. Waste-to-biofuel: Production of biobutanol from sago waste residues. Environ. Technol., 38: 1725-1734.
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  12. Kaliaperumal, J., N. Hari, P. Pavankumar and N. Elangovan, 2016. pACC1 peptide loaded chitosan nanoparticles induces apoptosis via reduced fatty acid synthesis in MDA-MB-231 cells. Applied Nanosci., 6: 615-627.
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  13. Ganesan, S., I.G. Babu, D. Mahendran, P.I. Arulselvi, N. Elangovan, N. Geetha and P. Venkatachalam, 2016. Green engineering of titanium dioxide nanoparticles using Ageratina altissima (L.) King & H.E. Robines. medicinal plant aqueous leaf extracts for enhanced photocatalytic activity. Ann. Phytomed., 5: 69-75.
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  14. Subramanian, R., V. Raj, K. Manigandan and N. Elangovan, 2015. Antioxidant activity of hopeaphenol isolated from Shorea roxburghii stem bark extract. J. Taibah Univ. Sci., 9: 237-244.
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  15. Selvakumar, G.P., T. Manivasagam, K.R. Rekha, R.L. Jayaraj and N. Elangovan, 2015. Escin, a novel triterpene, mitigates chronic MPTP/p-induced dopaminergic toxicity by attenuating mitochondrial dysfunction, oxidative stress and apoptosis. J. Mol. Neurosci., 55: 184-197.
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  16. Manigandan, K., R.L. Jayaraj, K. Jagatheesh and N. Elangovan, 2015. Taxifolin mitigates oxidative DNA damage in vitro and protects zebrafish (Danio rerio) embryos against cadmium toxicity. Environ. Toxicol. Pharmacol., 39: 1252-1261.
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  17. Manigandan, K., D. Manimaran, R.L. Jayaraj, N. Elangovan, V. Dhivya and A. Kaphle, 2015. Taxifolin curbs NF-κB-mediated Wnt/β-catenin signaling via up-regulating Nrf2 pathway in experimental colon carcinogenesis. Biochimie, 119: 103-112.
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  18. Davidraj, J., N. Elangovan and I.A. Padikasan, 2015. Molecular characterization and enzyme analysis of butanol tolerant bacterium Paenibacillus sp AS2 I. J. Life Sci. Technol., 3: 11-15.
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  19. Anbukkarasi, V., R. Srinivasan and N. Elangovan, 2015. Antimicrobial activity of green synthesized zinc oxide nanoparticles from Emblica officinalis. Int. J. Pharmaceut. Sci. Rev. Res., 5: 1354-1359.
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  20. Ravindar, D.J., P.I. Arulselvi and N. Elangovan, 2014. Isolation and molecular characterization of butanol tolerant bacterial strains for improved biobutanol production. J. Environ. Biol., 35: 1131-1136.
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  21. Rangasamy, K. and E. Namasivayam, 2014. In vitro antioxidant and free radical scavenging activity of isolongifolene. Asian J. Biol. Sci., 7: 13-23.
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  22. Manigandan, K., R.L. Jayaraj and N. Elangovan, 2014. Taxifolin ameliorates 1,2-dimethylhydrazine induced cell proliferation and redox avulsions in mice colon carcinogenesis. Biomed. Prev. Nutr., 4: 499-509.
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  23. Krishnan, M., R.L. Jayaraj, J. Megala and N. Elangovan, 2014. Antioxidant mediated antiulcer effect of Eupatorium triplinerve vahl against acetic acid induced ulcerative colitis in mice. Biomed. Aging Pathol., 4: 153-160.
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  24. Karuppanan, M., M. Krishnan, P. Padarthi and E. Namasivayam, 2014. Hepatoprotective and antioxidant effect of Mangifera indica leaf extracts against mercuric chloride-induced liver toxicity in mice. Euroasian J. Hepato-Gastroenterol., 4: 18-24.
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  25. Kaliyaperumal, J., P.K. Padarthi, K. Rangasamy and N. Elangovan, 2014. Development and validation of HPLC method for the quantification of anticancer peptide. Chem. Sci. Transact., 3: 1-6.
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  26. Kaliaperumal, J., V.C. Mohan and E. Namasivayam, 2014. In silico evaluation of anti-cancer peptides on BRCA1 targeting. Asian J. Biol. Sci., 7: 178-182.
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  27. Kaliaperumal, J., P. Padarthi, N. Elangovan and N. Hari, 2014. Anti-tumorigenic effect of nano formulated peptide pACC1 by diminishing de novo lipogenisis in DMBA induced mammary carcinoma rat model. Biomed. Pharmacother., 68: 763-773.
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  28. Kaliaperumal, J., K. Rangasamy, P. Parvathavarthini, P. Padarthi and N. Elangovan, 2014. Hemolytic and DNA nicking studies of anti-cancer peptide. Nat. J. Physiol. Pharm. Pharmacol., 4: 78-81.
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  29. Jayaraj, R.L., N. Elangovan, K. Manigandan, S. Singh and S. Shukla, 2014. CNB-001 a novel curcumin derivative, guards dopamine neurons in MPTP model of Parkinson's disease. BioMed Res. Int., Vol. 2014. 10.1155/2014/236182.
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  30. Jayaraj, R.L., N. Elangovan, C. Dhanalakshmi, T. Manivasagam and M.M. Essa, 2014. CNB-001, a novel pyrazole derivative mitigates motor impairments associated with neurodegeneration via suppression of neuroinflammatory and apoptotic response in experimental Parkinson's disease mice. Chemico-Biol. Interact., 220: 149-157.
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  31. Jayaraj, R.L. and N. Elangovan, 2014. In vitro antioxidant potential and deoxyribonucleic acid protecting activity of CNB-001, a novel pyrazole derivative of curcumin. Chron. Young Sci., 5: 44-52.
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  32. Jayaraj, R.L and N. Elangovan, 2014. In silico identification of potent inhibitors of alpha-synuclein aggregation and its in vivo evaluation using MPTP induced Parkinson mice model. Biomed. Aging Pathol., 4: 147-152.
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  33. Jagatheesh, K., P.P. Kumar, K. Padmavathi, R. Kowsalya and N. Elangovan, 2014. Extensive pertinence of carbon nanotubes. Int. J. pharm. Technol., 6: 17-27.
  34. De Oliveira, M.R., N. Elangovan, M. Ljubkovic and A. Baranova, 2014. The roads to mitochondrial dysfunction. J. Biomed. Biotechnol., Vol. 2014. 10.1155/2015/235370.
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  35. Subramanian, S., N. Elangovan, R.G. Menezes and P. Thirumalaikolundusubramanian, 2013. Soy milk toxicity: Cause for concern. J. Postgrad. Med., 59: 249-250.
  36. Ravindar, D.J. and N. Elangovan, 2013. Molecular identification of amylase producing Bacillus subtilis and detection of optimal conditions. J. Pharmacy Res., 6: 426-430.
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  37. Prasannaraj, G., R.L. Jayaraj, J.D. Ravindar and N. Elangovan, 2013. In vivo antioxidant potential of Thespesia populnea L., bark extract against mercury induced oxidative stress. Int. J. Pharm. Res., 5: 21-25.
  38. Padarthi, P.K., S. Sridhar, K Jagatheesh and. N. Elangovan, 2013. Synthesis and biological activity of imidazole derived chalcones and it’spyrimidines. Int. J. Res. Ayurveda Pharm., 4: 355-362.
  39. Padarthi, P.K., K. Jagatheesh, R. Kowsalya, C.M. Babu and N. Elangovan, 2013. Protective effect of Chenopodium album ethanolic extract against aspirin induced peptic ulcer in rat model. Int. J. Phytopharmacol., 2: 99-105.
  40. Padarthi, P.K. and E. Namasivayam, 2013. Synthesis and biological evaluation of chalcones from 2-acetyl-5-methylfuran. Int. J. Pharm. Sci. Res., 4: 2629-2638.
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  41. Kowsalya, R., K. Jagatheesh, P.K. Padarthi and N. Elangovan, 2013. A functional approach on neutrophil gelatinase associated lipocalin (NGAL)–lipocalin family. Int. J. Bioassays, 2: 483-487.
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  42. Jayaraj, R.L., V. Ranjani, K. Manigandan and N. Elangovan, 2013. In silico docking studies to identify potent inhibitors of alpha-synuclein aggregation in parkinson disease. Asian J. Pharm. Clin. Res., 6: 127-131.
  43. Jayaraj, R.L., V. Chandramohan and N. Elangovan, 2013. Nanomedicines for Parkinson disease: current Status and future perspective. Int. J. Pharm. Bio Sci., 4: 692-704.
  44. Jayaraj, R.L., K. Tamilselvam, T. Manivasagam and N. Elangovan, 2013. Neuroprotective effect of CNB-001, a novel pyrazole derivative of curcumin on biochemical and apoptotic markers against rotenone-induced SK-N-SH cellular model of Parkinson’s disease. J. Mol. Neurosci., 51: 863-870.
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  45. Jayaraj, R.L., V. Chandramohan, M. Dammalli, D.J. Ravindar, K. Manigandan, P.K. Padarthi and N. Elangovan, 2013. Computational strategy for identifying inhibitors of alpha-synuclein aggregation in Parkinson disease. Pharmanest: Int. J. Adv. Pharma. Sci., 4: 1029-1045.
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  46. Jagatheesh, K. and N. Elangovan, 2013. Peptides a novel kernel for next generation cancer therapy. J. Pharm. Sci. Innov., 5: 24-28.
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  47. Gnanaraj, M., R. Kowsalya, K. Padmavathi and N. Elangovan, 2013. Cloning of a gene encoding testis specific serine/threonine kinase 3 from Mus musculus. Int. J. Curr. Res., 5: 157-159.
  48. Singal, V.K., A.K. Singal, K. Jagatheesh, K. Padmavathi and N. Elangovan, 2012. Multifunctional role of green blood therapy to cure for many diseases. Chron. Young Sci., 3: 12-16.
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  49. Padarthi, P.K., V. Chandramohan, R.L. Jayaraj, K. Jagathesh and N. Elangovan, 2012. Chalcones as effective Antimicrobials - a comparative in silico approach. Int. J. Chem. Pharm. Sci., 3: 67-74.
  50. Jayaraj, R.J., J.D. Ravindar, K. Manigandan, P.K. Padarthi and N. Elangovan, 2012. An overview of parkinson's disease and oxidative stress: Herbal scenario. Neuropathol. Dis., 1: 95-122.
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  51. Jagatheesh, K., M.M. Hussain and N. Elangovan, 2012. Pavan Kumar padarthi and singhal anil kumar clinical evaluation of the efficacy of different doses of sibutramine on obesity. Indo-Glob. Res. J. Pharm. Res., 2: 205-209.
  52. Deleury, E., G. Debreuil, N. Elangovan, E. Wajnberg and J.M. Reichhart et al., 2012. Specific versus non-specific immune responses in an invertebrate species evidenced by a comparative de novo sequencing study. Plos One, Vol. 7. 10.1371/journal.pone.0032512.
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  53. Padmavathi, K., M. Gnanaraj, R. Kowsalya and N. Elangovan, 2011. Molecular cloning and partial characterization of testis specific gene tsg23 in swiss mouse. Biosci., 2: 16-21.
  54. Namasivayam, E., J.D. Ravindar, K. Mariappan, J. Akhil, K. Mukesh and R. Jayaraj, 2011. Production of extracellular pectinase by Bacillus cereus isolated from market solid waste. J. Bioanal. Biomed., 3: 70-75.
  55. Kowsalya, R., Gnanaraj, K. Padmavathi and N. Elangovan, 2011. Expression of TESF-1 gene in swiss albino mouse. Int. J. Chem. Pharm. Sci., 2: 22-25.
  56. Jagatheesh, K., P. Pavankumar, N. Elangovan, P. Padmavathi, D. Swathi and M. Tryphena, 2011. Applications of proteomics in animal model. Int. J. Pharm., 1: 1-14.
  57. Jagatheesh, K., B.J. Sanofer, N. Elangovan and P.P. Kumar, 2011. Phytochemical, anti- microbial, anti-inflammatory, anti-cancer, hepatoprotective evaluation of Mollugo pentaphylla Lin. Int. J. Curr. Sci. Technol., 2: 32-40.
  58. Yuvaraj, G., P.P. Kumar and N. Elangovan, 2010. The simultaneous estimation of aceclofenac, paracetamol and chlorzozazone in pharmaceutical dosage forms By HPTLC. Int. J. Chem. Pharm. Sci., 1: 24-27.
  59. Jagatheesh, K., V. Arumugam, N. Elangovan and P.P. Kumar, 2010. Evaluation of the anti-tumor and antioxidant activity of Morphophallus paeonifolius on DMBA induced mammary carcinoma. Int. J. Chem. Pharm. Sci., 1: 40-49.
  60. Pei-Tzu, L., L. Ying-Chu, N. Elangovan and C. Sin-Tak, 2007. Mouse 24p3 protein has an effect on l929 cell viability. Int. J. Biol. Sci., 3: 100-107.
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  61. Elangovan, N., C. Tzeon-Jye, T. Woan-Fang and C. Sin-Tak, 2006. Cyclophosphamide treatment causes impairment of sperm and its fertilizing ability in mice. Toxicology, 222: 60-70.
  62. Chou, H.Y., N. Elangovan, Y.C. Lee, H.H. Lin and S.T. Chu, 2006. Internalization and trafficking of mouse 24p3 protein in L929 cells. J. Endocrinol., 191: 239-247.
  63. Lee, Y.C., N. Elangovan, W.F. Tzeng and S.T. Chu, 2005. Mouse uterine 24p3 protein as a suppressor of sperm acrosome reaction. Mol. Biol. Reports, 32: 237-245.
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  64. Elangovan, N., Y.C. Lee, W.F. Tzeng and S.T. Chu, 2004. Delivery of ferric ion to mouse spermatozoa is mediated by lipocalin internalization. Biochem. Biophys. Res. Commun., 319: 1096-1104.
  65. Elangovan, N., P.S. Sudhakar Gandhi and P.T. Kalaichelvan, 2003. Utilization of lignin related phenolic derivatives by Flavobacterium sp. Asian J. Microbiol. Biotechnol. Envron. Sci., 5: 177-182.
  66. Elangovan, N., P.S. Sudhakar and P.T. Kalaichelvan, 2002. A comparative study on the potential of free cells and immobilized cells of Flavobacterium sp. in treatment of tannery effluent. Res. J. Chem. Environ., 6: 31-36.
  67. Elangovan, N., P.S. Gandhi, T. Kumaran and P.T. Kalaichelvan, 2000. Degradation of aromatic substances by a marine photosynthetic bacterium Rhodopseudomonas palustris (KK1). Indian J. Environ. Prot., 20: 366-371.
  68. Saravanan, P., A. Saravanan, N. Elangovan and P.T. Kalaichelvan, 1999. Decolourization of tannery effluent by Flavobacterium sp. EK~ 1. Indian J. Environ. Prot., 19: 19-24.
  69. Kalaichelvan, P.T. and N. Elangovan, 1995. Effects of phenolics on Drechslera oryzae. Indian Phytopath, 48: 271-274.
  70. Elangovan, N., T. Stevens and P.T. Kalaichelvan, 1995. Effect of salicylic acid on Phaseolus aureus seed germination. J. Ecotoxicol. Environ. Monit., 5: 67-70.