Prof. Nedime  Serakinci
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Prof. Nedime Serakinci

Professor
International Cyprus University / European University of Lefke


Highest Degree
Ph.D. in Medical Biology and Genetics from Marmara University, Turkiye

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Biography

Dr. Nedime Serakinci is currently working as Professor and Department leader of Medical Genetics, Near East University Northern Cyprus. She obtained her PhD in Medical Biology and Genetics from Marmara University, Istanbul, Turkey. In past she worked as Research Scientist at Istanbul University, Research Fellow, Post-doctoral Research Fellow at Danish Cancer Society, Research Assistant Professor at Aarhus Amtssygehus, Cancercytogenetics Laboratory Aarhus Denmark, Assistant Professor, Associate Professor at Aarhus University, and Assistant Professor at University of Southern Denmark. She has been invited to delivered special lectures in many national and international conferences and workshops. She is member of following scientific societies; American Society of Human Genetics, American Society of Gene therapy, European Cytogenetics Association, and European Society of Human Genetics. She is external supervisor and co-supervisor for 5 international Ph.D. students and several undergraduate students and 5 Post-docs. She has Published 29 research papers in international journals (abstracts are not included) and 5 book chapters and presented 25 oral presentations and 18 posters and gave more than 20 invited talks in seminars.

Area of Interest:

Medicine
100%
Cancer
62%
Regenerative Medicine
90%
Oncogene
75%
Medical Sciences
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
0
Abstracts
0

Selected Publications

  1. Danladi C.D. and N. Serakinci, 2022. Comparative studies of breast cancer risk prediction models as screening tools for women in low -and middle-income societies. Res. Square, 10.21203/rs.3.rs-1395809/v1.
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  2. Sehirli, A.O., S. Sayıner, U. Chukwunyere and N. Serakinci, 2021. Role of melatonin in angiotensin and aging. Molecules, Vol. 26. 10.3390/molecules26154666.
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  3. Kaya, M., A.M. Abuaisha, N. Serakinci and S. Ozturk, 2021. Potential therapeutic road for targeting the SARS-CoV-2 at throat. Bratislava Med. J., 122: 206-211.
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  4. Kashoura, Y., N. Serakinci, N. Beleva, N.I. Kaçamak, G. Tuncel and U. Oz, 2021. WNT signaling pathway genes expression profile in isolated hypodontia. Appl. Nanosci. 10.1007/s13204-021-01850-3.
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  5. Sehirli, A.O., S. Sayiner, A. Velioglu-Ogunc, N. Serakinci and E. Eksioglu-Demiralpet al., 2020. The influence of n-acetylcysteine alone and in combination with angiotensin converting enzyme inhibitor and angiotensin receptor antagonist on systemic and tissue levels in rats with experimentally-induced chronic renal failure. Pakistan J. Zool., 52: 1263-1274.
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  6. Cagsin, H., A. Uzan, O. Tosun, F. Rasmussen and N. Serakinci, 2020. Tissue-specific ultra-short telomeres in chronic obstructive pulmonary disease. Int. J. Chron. Obstructive Pulm. Dis., 15: 2751-2757.
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  7. Serakinci, N. and H. Cagsin, 2019. Turning stem cells homing potential into cancer specific drug delivery machines. Ann. Transl. Med., 7: S148-S148.
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  8. Pervaiz, R., P. Tulay, F. Faisal and N. Serakinci, 2017. Incidence of cancer in the Turkish republic of Northern Cyprus. Turk. J. Med. Sci., 47: 523-530.
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  9. Pervaiz, R., O. Tosun, H. Besim and N. Serakinci, 2017. Dietary factors modify post-menopausal breast cancer risk: A case-control study from Turkish Cypriot population. Biomed. Res. Therapy, 4: 1171-1184.
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  10. Akcan, N., N. Serakinci, B. Turkgenc, R. Bundak, N. Bahceciler and S.G. Temel, 2017. A novel TBX19 gene mutation in a case of congenital isolated adrenocorticotropic hormone deficiency presenting with recurrent respiratory tract infections. Front. Endocrinol., Vol. 8. 10.3389/fendo.2017.00064.
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  11. Tulay, P. and N. Serakinci, 2016. The route to HPV-associated neoplastic transformation: A review of the literature. Crit. Rev. Eukaryotic Gene Expression, 26: 27-39.
  12. Serakinci, N., R. Kalkan and P. Tulay, 2016. Double-faced role of human mesenchymal stem cells and their role/challenges in cancer therapy. Curr. Stem Cell Res. Therapy, 11: 343-351.
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  13. Orun, O., P.M. Tiber and N. Serakinci, 2016. Partial knockdown of TRF2 increase radiosensitivity of human mesenchymal stem cells. Int. J. Biol. Macromol., 90: 53-58.
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  14. Kalkan, R., N. Ozdag, R. Bundak, A. Cirakoglu and N. Serakinci, 2016. A unique mosaic Turner syndrome patient with androgen receptor gene derived marker chromosome. Syst. Biol. Reprod. Med., 62: 77-83.
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  15. Kalkan, R. and N. Serakinci, 2016. Human mesenchymal stem cells in cancer therapy. Crit. Rev. Eukaryotic Gene Expression, 26: 41-48.
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  16. Eker, A., U. Fahrioglu and N. Serakinci, 2016. Late onset tremor and ataxia syndrome: FXTAS and its ignored peripheral nervous system findings in diagnostic criteria. Noro Psikiyatri Arsivi, 53: 92-93.
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  17. Becer, E., M. Kizilkanat, M. Tinazli and N. Serakinci, 2016. Association between leptin G-2548A gene polymorphism, plasma leptin levels and lipid profiles in Turkish Cypriot obese subjects. Turk. J. Biochem., 41: 1-7.
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  18. Kopf, A., M. Bicak, R. Kottmann, J. Schnetzer and I. Kostadinov et al., 2015. The ocean sampling day consortium. GigaScience, Vol. 4. 10.1186/s13742-015-0066-5.
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  19. Ergoren, M.C., R.H. Pirzada, M. Arici and N. Serakinci, 2015. Near east university genetic mutation database (NEU-GD): The first mutation database of Northern Cyprus. Gene, 571: 145-148.
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  20. Serakinci, N., U. Fahrioglu and R. Christensen, 2014. Mesenchymal stem cells, cancer challenges and new directions. Eur. J. Cancer, 50: 1522-1530.
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  21. Becer, E., G. Mehmetcik, H. Bareke and N. Serakınci, 2013. Association of leptin receptor gene Q223R polymorphism on lipid profiles in comparison study between obese and non-obese subjects. Gene, 529: 16-20.
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  22. Harbo, M., S. Koelvraa, N. Serakinci and L. Bendix, 2012. Telomere dynamics in human mesenchymal stem cells after exposure to acute oxidative stress. DNA Repair, 11: 774-779.
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  23. Serakinci, N., R. Christensen, U. Fahrioglu, F.B. Sorensen and F. Dagnaes-Hansen et al., 2011. Mesenchymal stem cells as therapeutic delivery vehicles targeting tumor stroma. Cancer Biotherapy Radiopharmaceuticals, 26: 767-773.
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  24. Lafferty-Whyte, K., C.J. Cairney, M.B. Will, N. Serakinci and M.G. Daidone et al., 2009. A gene expression signature classifying telomerase and ALT immortalization reveals an hTERT regulatory network and suggests a mesenchymal stem cell origin for ALT. Oncogene, 28: 3765-3774.
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  25. Serakinci, N., J. Graakjaer and S. Kolvraa, 2008. Telomere stability and telomerase in mesenchymal stem cells. Biochimie, 90: 33-40.
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  26. Christensen, R., J. Alsner, F.B. Sorensen, F. Dagnaes-Hansen, S. Kolvraa and N. Serakinci, 2008. Transformation of human mesenchymal stem cells in radiation carcinogenesis: Long-term effect of ionizing radiation. Regen Med., 3: 849-861.
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  27. Serakinci, N., R. Christensen, J. Graakjaer, C.J. Anderson and W.N. Keith et al., 2007. Immortalized adult human mesenchymal stem cells are less radiosensitive than their mortal counterpar. Exp. Cell. Res., 313: 1056-1067.
  28. Serakinci, N. and C. Erzik, 2007. Rod for understnding cancer stem cells: Model cell lines. Regen Med., 2: 957-965.
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  29. Graakjaer, J., R. Christensen, S. Kolvraa and N. Serakinci, 2007. Mesenchymal stem cells with high telomerase expression do not actively restore their chromosome arm specific telomere length pattern after exposure to ionizing radiation. BMC Mol. Biol., Vol. 8. 10.1186/1471-2199-8-49.
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  30. Serakinci, N., S.F. Hoare, M. Kassem, S.P. Atkinson and W.N. Keith, 2006. Telomerase promoter reprogramming and interaction with general transcription factors in the human mesenchymal stem cell. Regenerative Med., 1: 125-131.
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  31. Serakinci, N. and W.N. Keith, 2006. Therapeutic potential of adult stem cells. Eur. J. Cancer, 42: 1243-1246.
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  32. Palanduz, S., N. Serakinci, K. Cefle, M. Aktan and G. Tutkan et al., 2006. A different approach to telomere analysis with ddPRINS in chronic lymphocytic leukemia. Eur. J. Med. Genet., 49: 63-69.
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  33. Serakinci, N., P. Guldberg, J.S. Burns, B. Abdallah, H. Schrodder, T. Jensen and M. Kassem, 2004. Adult human mesenchymal stem cell as a target for neoplastic transformation. Oncogene, 23: 5095-5098.
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  34. Keith, W.N., T. Vulliamy, J. Zhao, C. Ar and C. Erzik et al., 2004. A mutation in a functional Sp1 binding site of the telomerase RNA gene (hTERC) promoter in a patient with Paroxysmal Nocturnal Haemoglobinuria. BMC Hematol., Vol. 4. 10.1186/1471-2326-4-3.
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  35. Simonsen, J.L., C. Rosada, N. Serakinci, J. Justesen and K. Stenderup et al., 2002. Telomerase expression extends the proliferative life-span and maintains the osteogenic potential of human bone marrow stromal cells. Nat. Biotechnol., 20: 592-596.
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  36. Serakinci, N., M. Ostergaard, H. Larsen, B. Madsen, B. Pedersen and J. Koch, 2002. Multiple telomeric aberrations in a telomerase-positive leukemia patient. Cancer Genet. Cytogenetics, 138: 11-16.
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  37. Serakinci, N. and J.E. Koch, 2002. Telomerase activity in human leukemic cells with or without monosomy 7 or 7q. BMC Med. Genet., Vol. 3. 10.1186/1471-2350-3-11.
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  38. Serakıncı, N., B. Pedersen and J. Koch, 2001. Expansion of repetitive DNA into cytogenetically visible elements. Cytogenetic Genome Res., 92: 182-185.
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