Dr. Chih-Hsuan Hsia
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Dr. Chih-Hsuan Hsia

Research Scientist
Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taiwan

Highest Degree
Ph.D. in Medicine from Taipei Medical University, Taiwan

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Area of Interest:

Medicine
100%
Chemotherapy
62%
Macrophages
90%
Drugs
75%
Management
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
0
Abstracts
0

Selected Publications

  1. Yang, C.H., C.W. Hsia, T. Jayakumar, J.R. Sheu and C.H. Hsia et al., 2018. Structure-activity relationship study of newly synthesized iridium-III complexes as potential series for treating thrombotic diseases. Int. J. Mol. Sci., Vol. 19. 10.3390/ijms19113641.
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  2. Shyu, R.S., T. Khamrang, J.R. Sheu, C.W. Hsia and M. Velusamy et al., 2018. Ir-6: A novel iridium (III) organometallic derivative for inhibition of human platelet activation. Bioinorg. Chem. Applic., Vol. 2018. 10.1155/2018/8291393.
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  3. Shyu, K.G., M. Velusamy, C.W. Hsia, C.H. Yang and C.H. Hsia et al., 2018. Novel iridium (III)‑derived organometallic compound for the inhibition of human platelet activation. Int. J. Mol. Sci., 41: 2589-2600.
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  4. Jayakumar, T., C.Y. Hsu, T. Khamrang, C.H. Hsia, C.W. Hsia, M. Manubolu and J.R. Sheu, 2018. Possible molecular targets of novel ruthenium complexes in antiplatelet therapy. Int. J. Mol. Sci., Vol. 19. 10.3390/ijms19061818.
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  5. Hsia, C.W., M.P. Wu, M. Velusamy, C.H. Hsia and D.S. Chou et al., 2018. Novel therapeutic agent against platelet activation in vitro and arterial thrombosis in vivo by morin hydrate. Int. J. Mol. Sci., Vol. 19. 10.3390/ijms19082386.
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  6. Hsia, C.H., W.J. Lu, K.H. Lin, D.S. Chou and P. Geraldine et al., 2018. Norcantharidin, a clinical used chemotherapeutic agent, acts as a powerful inhibitor by interfering with fibrinogen-integrin α II bβ3 binding in human platelets. J. Cell. Mol. Med., 22: 2142-2152.
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  7. Hsia, C.H., T. Jayakumar, J.R. Sheu, S.Y. Tsao and M. Velusamy et al., 2018. Structure-antiplatelet activity relationships of novel ruthenium (II) complexes: Investigation of its molecular targets. Molecules, Vol. 23. 10.3390/molecules23020477.
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  8. Hsia, C.H., M. Velusamy, T. Jayakumar, Y.J. Chen and C.W. Hsia et al., 2018. Mechanisms of TQ-6, a novel ruthenium-derivative compound, against Lipopolysaccharide-induced in vitro macrophage activation and liver injury in experimental mice: The crucial role of p38 MAPK and NF-κB Signaling. Cells, Vol. 7. 10.3390/cells7110217.
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  9. Yao, W.C., L.T. Yuan, W.B. Yang, C.H. Hsia and L.T. Huang et al., 2017. Development of benzimidazole derivatives as novel anti-platelet drugs. Curr. Pharm. Biotechnol., 18: 594-605.
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  10. Sheu, J.R., Z.C. Chen, T. Jayakumar, D.S. Chou and T.L. Yen et al., 2017. A novel indication of platonin, a therapeutic immunomodulating medicine, on neuroprotection against ischemic stroke in mice. Scient. Rep., Vol. 7. 10.1038/srep42277.
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  11. Khamrang, T., K.C. Hung, C.H. Hsia, C.Y. Hsieh, M. Velusamy, T. Jayakumar and J.R. Sheu, 2017. Antiplatelet activity of a newly synthesized novel ruthenium (II): A potential role for Akt/JNK signaling. Int. J. Mol. Sci., Vol. 18. 10.3390/ijms18050916.
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  12. Hsia, C.W., M. Velusamy, J.T. Tsao, C.H. Hsia and D.S. Chou et al., 2017. New therapeutic agent against arterial thrombosis: An iridium(III)-derived organometallic compound. Int. J. Mol. Sci., Vol. 18. 10.3390/ijms18122616.
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  13. Hsia, C.H., M. Velusamy, J.R. Sheu, T. Khamrang and T. Jayakumar et al., 2017. A novel ruthenium (II)-derived organometallic compound, TQ-6, potently inhibits platelet aggregation: Ex vivo and in vivo studies. Scient. Rep., Vol. 7. 10.1038/s41598-017-09695-z.
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