Prof. Yu-Chih Liang
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Prof. Yu-Chih Liang

Professor and Chairman
Taipei Medical University, Taiwan

Highest Degree
Ph.D. in Biochemistry from National Taiwan University, Taiwan

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Biography

Yu-Chih Liang is a Professor at School of Medical Laboratory Science and Biotechnology, College of Medical Science and Technology, Taipei Medical University Prof. Liang has over 60 scientific papers and projects either presented or published.
His research focus on the cancer research, including signal transduction and gene expression regulation.

Area of Interest:

Pharmacology and Toxicology
100%
Drug Discovery
62%
Molecular Mechanisms
90%
Signal Transduction
75%
Gene Regulation
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
0
Abstracts
0

Selected Publications

  1. Chin, L.H., S.P. Hsu, W.B. Zhong and Y.C. Liang, 2016. Involvement of cysteine-rich protein 61 in the epidermal growth factor-induced migration of human anaplastic thyroid cancer cells. Mol. Carcinogen., 55: 622-632.
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  2. Suk, F.M., S.Y. Lin, R.J. Lin, Y.H. Hsine, Y.J. Liao, S.U. Fang and Y.C. Liang, 2015. Bortezomib inhibits Burkitt's lymphoma cell proliferation by downregulating sumoylated hnRNP K and c-Myc expression. Oncotarget, 6: 25988-26001.
    CrossRef  |  PubMed  |  Direct Link  |  
  3. Liu, J.J., H.H. Wu, T.H. Chen, W. Leung and Y.C. Liang, 2015. 15,16-dihydrotanshinone I from the functional food Salvia miltiorrhiza exhibits anticancer activity in human HL-60 leukemia cells: In vitro and in vivo studies. Int. J. Mol. Sci., 16: 19387-19400.
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  4. Liao, Y.J., C.C. Fang, C.H. Yen, S.M. Hsu and C.K. Wang et al., 2015. Niemann-Pick type C2 protein regulates liver cancer progression via modulating ERK1/2 pathway: Clinicopathological correlations and therapeutical implications. Int. J. Cancer, 137: 1341-1351.
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  5. Liang, Y.C., W.C. Lin, Y.J. Lin and J.C. Lin, 2015. The impact of RNA binding motif protein 4-regulated splicing cascade on the progression and metabolism of colorectal cancer cells. Oncotarget, 6: 38046-38060.
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  6. Lee, W.H., H.H. Wu, W.J. Huang, Y.N. Li, R.J. Lin, S.Y. Lin and Y.C. Liang, 2015. N-hydroxycinnamide derivatives of osthole ameliorate hyperglycemia through activation of AMPK and p38 MAPK. Molecules, 20: 4516-4529.
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  7. Chin, L.H., S.P. Hsu, W.B. Zhong and Y.C. Liang, 2015. Combined treatment with troglitazone and lovastatin inhibited epidermal growth factor-induced migration through the downregulation of cysteine-rich protein 61 in human anaplastic thyroid cancer cells. PLoS ONE, Vol. 10. 10.1371/journal.pone.0118674.
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  8. Chang, C.C., Y.H. Tsai, Y. Liu, S.Y. Lin and Y.C. Liang, 2015. Calcium-containing crystals enhance receptor activator of nuclear factor κB ligand/macrophage colony-stimulating factor-mediated osteoclastogenesis via extracellular-signal-regulated kinase and p38 pathways. Rheumatology, 54: 1913-1922.
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  9. Chang, C.C., L.Y. Chen, K.H. Yang, Q.Y. Chen, Y.C. Liang, S.Y. Lin and Y.C. Liu, 2015. Surface-enhanced Raman scattering on a silver film-modified Au nanoparticle-decorated SiO2 mask array. RSC Adv., 5: 66096-66103.
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  10. Liu, L.Y., W.J. Huang, F.M. Ho, R.J. Lin, S.Y. Lin, F.M. Suk and Y.C. Liang, 2014. N-Hydroxycinnamide derivatives of osthole inhibit cell migration and invasion by suppressing Smad2 and Akt pathways in human colorectal adenocarcinoma cells. Chemico-Biol. Interact., 217: 1-8.
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  11. Lin, Y.L., Y.C. Hu, C.C. Liang, S.Y. Lin, Y.C. Liang, H.P. Yuan and B.L. Chiang, 2014. Enterovirus-71 virus-like particles induce the activation and maturation of human monocyte-derived dendritic cells through TLR4 signaling. PLoS ONE, Vol. 9. 10.1371/journal.pone.0111496.
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  12. Lin, R.J., J.S. Chu, H.L. Chien, C.H. Tseng and P.C. Ko et al., 2014. MCPIP1 suppresses hepatitis C virus replication and negatively regulates virus-induced proinflammatory cytokine responses. J. Immunol., 193: 4159-4168.
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  13. Wu, S.S., L.G. Chen, R.J. Lin, S.Y. Lin, Y.E. Lo and Y.C. Liang, 2013. Cytotoxicity of (-)-vitisin B in human leukemia cells. Drug Chem. Toxicol., 36: 313-319.
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  14. Suk, F.M., W.J. Jou, R.J. Lin, S.Y. Lin, F.Y. Tzeng and Y.C. Liang, 2013. 15,16-dihydrotanshinone I-induced apoptosis in human colorectal cancer cells: Involvement of ATF3. Anticancer Res., 33: 3225-3231.
    PubMed  |  Direct Link  |  
  15. Suk, F.M., G.S. Lien, W.J. Huang, C.N. Chen and S.Y. Lu et al., 2013. A Taiwanese propolis derivative induces apoptosis through inducing endoplasmic reticular stress and activating transcription factor-3 in human hepatoma cells. Evidence-Based Complement. Altern. Med. 10.1155/2013/658370.
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  16. Liu, L.Y., W.J. Huang, R.J. Lin, S.Y. Lin and Y.C. Liang, 2013. N-Hydroxycinnamide derivatives of osthole presenting genotoxicity and cytotoxicity against human colon adenocarcinoma cells in vitro and in vivo. Chem. Res. Toxicol., 26: 1683-1691.
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  17. Keller, J.J., Y.C. Liang and H.C. Lin, 2012. Association between multiple sclerosis and erectile dysfunction: A nationwide case-control study. J. Sexual Med., 9: 1753-1759.
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  18. Chung, S.D., J.J. Keller, Y.C. Liang and H.C. Lin, 2012. Association between viral hepatitis and erectile dysfunction: A population-based case-control analysis. J. Sexual Med., 9: 1295-1302.
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  19. Chien, C.S., H.O. Ho, Y.C. Liang, P.H. Ko, M.T. Sheu and C.H. Chen, 2012. Incorporation of exudates of human platelet-rich fibrin gel in biodegradable fibrin scaffolds for tissue engineering of cartilage. J. Biomed. Mater. Res. Part B: Applied Biomater., 100: 948-955.
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  20. Zhong, W.B., S.P. Hsu, P.Y. Ho, Y.C. Liang, T.C. Chang and W.S. Lee, 2011. Lovastatin inhibits proliferation of anaplastic thyroid cancer cells through up-regulation of p27 by interfering with the Rho/ROCK-mediated pathway. Biochem. Pharmacol., 82: 1663-1672.
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  21. Wei, J.D., H. Tseng, E.T.H. Chen, C.H. Hung, Y.C. Liang, M.T. Sheu and C.H. Chen, 2011. Characterizations of chondrocyte attachment and proliferation scaffolds of PLLA and PBSA for use in cartilage tissue engineering. J. Biomater. Applic., 26: 963-985.
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  22. Lee, W.H., R.J. Lin, S.Y. Lin, Y.C. Chen, H.M. Lin and Y.C. Liang, 2011. Osthole enhances glucose uptake through activation of AMP-activated protein kinase in skeletal muscle cells. J. Agric. Food Chem., 59: 12874-12881.
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  23. Huang, W.J., Y.C. Liang, S.E. Chuang, L.L. Chi and C.Y. Lee et al., 2011. NBM-HD-1: A novel histone deacetylase inhibitor with anticancer activity. Evidence-Based Complement. Altern. Med. 10.1155/2012/781417.
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  24. Chuang, M.T., F.M. Ho, C.C. Wu, S.Y. Zhuang, S.Y. Lin, F.M. Suk and Y.C. Liang, 2011. 15,16-Dihydrotanshinone I, a compound of Salvia miltiorrhiza Bunge, induces apoptosis through inducing endoplasmic reticular stress in human prostate carcinoma cells. Evidence-Based Complement. Altern. Med. 10.1155/2011/865435.
    CrossRef  |  Direct Link  |  
  25. Chen, C.H., M.Y. Chien, Y.C. Liang, D.Z. Liu and M.L. Hu, 2011. An in vitro hyperbaric oxygen system for evaluation of free radical damage and protection by catechins on hemorheological parameters. Clin. Hemorheol. Microcirc., 48: 211-221.
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  26. Chang, C.J., Y.H. Yang, Y.C. Liang, C.J. Chiu, K.H. Chu, H.N. Chou and B.L. Chiang, 2011. A novel phycobiliprotein alleviates allergic airway inflammation by modulating immune responses. Am. J. Respir. Crit. Care Med., 183: 15-25.
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  27. Wang, L.C., K.H. Chu, Y.C. Liang, Y.L. Lin and B.L. Chiang, 2010. Caffeic acid phenethyl ester inhibits nuclear factor-κB and protein kinase B signalling pathways and induces caspase-3 expression in primary human CD4+ T cells. Clin. Exp. Immunol., 160: 223-232.
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  28. Wang, C.K., L.G. Chen, C.L. Wen, W.C. Hou and L.F. Hung et al., 2010. Neuroprotective activity of Vitis thunbergii var. taiwaniana extracts in vitro and in vivo. J. Med. Food, 13: 170-178.
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  29. Lin, L.C., F.M. Ho, S.J. Yen, P.Y. Wu, L.F. Hung, W.J. Huang and Y.C. Liang, 2010. Carbon monoxide induces cyclooxygenase-2 expression through MAPKs and PKG in phagocytes. Int. Immunopharmacol., 10: 1520-1525.
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  30. Chien, M.H., T.S. Lee, Y.C. Liang and W.S. Lee, 2010. β-sitosterol inhibits cell cycle progression of rat aortic smooth muscle cells through increases of p21cip1 protein. J. Agric. Food Chem., 58: 10064-10069.
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