Xiaolan Qi
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Xiaolan Qi

Professor
Guizhou medical university

Highest Degree
M.D. in Pathology and Pathophysiology from Guiyang Medical College, Guiyang, China

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Area of Interest:

Area of Interest
100%

Research Publications in Numbers

Books
0
Chapters
0
Articles
18
Abstracts
0

Selected Publications

  1. Wang, X.L., Y.X. Deng, Y.M. Gao, Y.T. Dong and F. Wang et al., 2020. Activation of α7 nACHR by PNU-282987 improves synaptic and cognitive functions through restoring the expression of synaptic-associated proteins and the CaM-caMKII-CREB signaling pathway. Aging, 12: 543-570.
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  2. Ren, J.M., S.L. Zhang, X.L. Wang, Z.Z. Guan and X.L. Qi, 2020. Expression levels of the α7 nicotinic acetylcholine receptor in the brains of patients with Alzheimer's disease and their effect on synaptic proteins in SH-SY5Y cells. Mol. Med. Rep., 22: 2063-2075.
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  3. Ren, J., X. Wang, Y. Gao, F. Wang, Z. Guan and X. Qi, 2019. The expression of the nicotinic acetylcholine receptor α3 subunit in the brains of patients with Alzheimer's disease and its effects on α- and γ-secretases and notch signal transduction in SH-SY5Y cells[J]. Int. J. Clin. Exp. Pathol., 12: 3644-3652.
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  4. Wu, C.X., Y.H. Wang, Y. Li, Z.Z. Guan and X.L. Qi, 2018. Changes of DNA repair gene methylation in blood of chronic fluorosis patients and rats. J. Trace Elem.s Med. Biol., 50: 223-228.
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  5. Hong, W., Y. Cheng, F. Rao, J. Yang and G. Cui et al., 2018. Co-infection of clostridioides (clostridium) difficile GMU1 and Bacillus cereus GMU2 in one patient in Guizhou, China. Anaerobe, 54: 159-163.
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  6. Chu, L.Z., Z.Z. Guan, J. Liu, H. Yang and X.L. Qi et al., 2014. Multifocal central nervous system hemangioblastoma: a case report and review of the literature. Genet. Mol. Res., 13: 7904-7911.
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  7. Xiao, H.T., X.L. Qi, Y. Liang, C.Y. Lin, X. Wang, Z.Z. Guan and X.Y. Hao, 2013. Membrane permeability-guided identification of neuroprotective components from Polygonum cuspidatun. Pharm. Biol., 52: 356-361.
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  8. Qi, X.L., X.L. Zhang, K. Ou-Yang, K.R. Shan and Z.Z. Guan, 2013. The influence of inhibiting or stimulating the expression of the α3 subunit of the nicotinic receptor in SH-SY5Y cells on levels of amyloid-β peptide and β-secretase. Neurochem. Int., 62: 79-83.
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  9. Qi, X.L., K. Ou-Yang, J.M. Ren, C.X. Wu, Y. Xiao, Y. Li and Z.Z. Guan, 2013. Preventing expression of the nicotinic receptor subunit α7 in SH-SY5y cells with interference RNA indicates that this receptor may protect against the neurotoxicity of Aβ. Neurochem. Res., 38: 943-950.
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  10. Deng, J., X.L. Qi, Z.Z. Guan, X.M. Yan, Y. Huang and Y.L. Wang, 2013. Pretreatment of SH-SY5Y cells with dicaffeoylquinic acids attenuates the reduced expression of nicotinic receptors, elevated level of oxidative stress and enhanced apoptosis caused by β-amyloid peptide. J. Pharm. Pharmacol., 65: 1736-1744.
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  11. Zhang, L.J., Y. Xiao, X.L. Qi, K.R. Shan and J.J. Pei et al., 2010. Cholinesterase activity and mRNA level of nicotinic acetylcholine receptors (α4 and β2 subunits) in blood of elderly Chinese diagnosed as Alzheimer's disease. J. Alzheimer Dis., 19: 849-858.
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  12. An, Y., X.L. Qi, J.J. Pei, Z. Tang, Y. Xiao and Z.Z. Guan, 2010. Amyloid precursor protein gene mutated at swedish 670/671 sites in vitro induces changed expression of nicotinic acetylcholine receptors and neurotoxicity. Neurochem. Int., 57: 647-654.
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  13. Tang, Z., Y. An, X. Qi, Y. Xiao, K. Shan and Z. Guan, 2008. Inhibiting gene expression of α3 nicotinic receptor in SH-SY5Y cells with the effects on app metabolism and antioxidation in Alzheimer's disease. Neurochem. Int., 53: 112-117.
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  14. Qi, X.L., A. Nordberg, J. Xiu and Z.Z. Guan, 2007. The consequences of reducing expression of the α7 nicotinic receptor by RNA interference and of stimulating its activity with an α7 agonist in SH-SY5Y cells indicate that this receptor plays a neuroprotective role in connection with the pathogenesis of Alzheimer's disease. Neurochem. Int., 51: 377-383.
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  15. Liu, R.Y., R. Gu, X.L. Qi, T. Zhang and Y. Zhao et al., 2007. Decreased nicotinic receptors and cognitive deficit in rats intracerebroventricularly injected with beta-amyloid peptide(1-42) and fed a high-cholesterol diet. J. Neurosci. Res., 86: 183-193.
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  16. Xiu, J., A. Nordberg, X. Qi and Z.Z. Guan, 2006. Influence of cholesterol and lovastatin on α-form of secreted amyloid precursor protein and expression of α7 nicotinic receptor on astrocytes. Neurochem. Int., 49: 459-465.
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  17. Qi, X.L., J. Xiu, K.R. Shan, Y. Xiao, R. Gu, R.Y. Liu and Z.Z. Guan, 2005. Oxidative stress induced by beta-amyloid peptide1–42 is involved in the altered composition of cellular membrane lipids and the decreased expression of nicotinic receptors in human SH-SY5Y neuroblastoma cells. Neurochem. Int., 46: 613-621.
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