Prof. Jong-Sup Bae
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Prof. Jong-Sup Bae

Professor & Vice Dean
Kyungpook National University, South Korea

Highest Degree
Ph.D. in Biochemistry from Saint Louis University, USA

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Area of Interest:

Biomedical Sciences
100%
Cell Physiology
62%
Inflammation
90%
Biochemistry
75%
Haemostasis
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
0
Abstracts
0

Selected Publications

  1. Yun, J.H., S.W. Park, K.J. Kim, J.S. Bae and E.H. Lee et al., 2017. Endothelial STAT3 activation increases vascular leakage through downregulating tight junction proteins: Implications for diabetic retinopathy. J. Cell. Physiol., 232: 1123-1134.
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  2. Min, G., S.K. Ku, T. Lee and J.S. Bae, 2017. Suppressive effects of zingerone on TGFBIp-mediated septic responses. Arch. Pharmacal Res., (In Press). 10.1007/s12272-017-0919-9.
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  3. Lee, W., S.K. Ku, M.A. Kim and J.S. Bae, 2017. Anti-factor Xa activities of zingerone with anti-platelet aggregation activity. Food Chem. Toxicol., 105: 186-193.
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  4. Lee, S.H., W. Lee, T. Nguyen, I.S. Um, J.S. Bae and E. Ma, 2017. Synthesis and thrombin, factor Xa and U46619 inhibitory effects of non-amidino and amidino N2-thiophenecarbonyl- and N2-tosylanthranilamides. Int. J. Mol. Sci., Vol. 18, No. 6. 10.3390/ijms18061144.
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  5. Lee, J., W. Lee, M. Kim, J.S. Hwang, M. Na and J.S. Bae, 2017. Inhibition of platelet aggregation and thrombosis by indole alkaloids isolated from the edible insect Protaetia brevitarsis seulensis (Kolbe). J. Cell. Mol. Med., 21: 1217-1227.
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  6. Lee, I.C., J. Kim and J.S. Bae, 2017. Anti-inflammatory effects of dabrafenib in vitro and in vivo. Can. J. Physiol. Pharmacol., 95: 697-707.
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  7. Lee, I.C. and J.S. Bae, 2017. Suppressive effects of pelargonidin on PolyPhosphate-mediated vascular inflammatory responses. Arch. Pharmacal Res., 40: 258-267.
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  8. Kwak, S., S.K. Ku, H. Kang, M.C. Baek and J.S. Bae, 2017. Methylthiouracil, a new treatment option for sepsis. Vasc. Pharmacol., 88: 1-10.
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  9. Ku, S.K., J. Kim, S.C. Kim and J.S. Bae, 2017. Suppressive effects of dabrafenib on endothelial protein C receptor shedding. Arch. Pharmacal Res., 40: 282-290.
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  10. Kang, H., S.K. Ku, J. Kim, J. Chung and S.C. Kim et al., 2017. Anti-vascular inflammatory effects of pentacyclic triterpenoids from Astilbe rivularis in vitro and in vivo. Chem.-Biol. Interact., 261: 127-138.
    CrossRef  |  Direct Link  |  
  11. Jeong, S., S.K. Ku and J.S. Bae, 2017. Anti-inflammatory effects of pelargonidin on TGFBIp-induced responses. Can. J. Physiol. Pharmacol., 95: 372-381.
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  12. Yang, E.J., W. Lee, K.S. Song and J.S. Bae, 2016. Ameliorative effect of a rarely occurring C-methylrotenoid on HMGB1-induced septic responses in vitro and in vivo. Biochem. Pharmacol., 110: 58-70.
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  13. Min, G., S.K. Ku, S. Jeong, M.C. Baek and J.S. Bae, 2016. Suppressive effects of methylthiouracil on polyphosphate-mediated vascular inflammatory responses. J. Cell. Mol. Med., 20: 2333-2340.
    CrossRef  |  Direct Link  |  
  14. Min, G., S.K. Ku, M.S. Park, T.J. Park, H.S. Lee and J.S. Bae, 2016. Anti-septic effects of pelargonidin on HMGB1-induced responses in vitro and in vivo. Arch. Pharmacal Res., 39: 1726-1738.
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  15. Lee, W., S.K. Ku, S. Park, K.M. Kim, H. Choi and J.S. Bae, 2016. Inhibitory effect of three diketopiperazines from marine-derived bacteria on HMGB1-induced septic responses in vitro and in vivo. Am. J. Chin. Med., 44: 1145-1166.
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  16. Lee, W., S.K. Ku, H. Choi and J.S. Bae, 2016. Inhibitory effects of three diketopiperazines from marine-derived bacteria on endothelial protein C receptor shedding in human endothelial cells and mice. Fitoterapia, 110: 181-188.
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  17. Lee, W., J. Lee, R. Kulkarni, M.A. Kim, J.S. Hwang, M. Na and J.S. Bae, 2016. Antithrombotic and antiplatelet activities of small-molecule alkaloids from Scolopendra subspinipes mutilans. Scient. Rep., Vol. 6. 10.1038/srep21956.
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  18. Lee, W., E.J. Yang, D.H. Park and J.S. Bae, 2016. Suppressive effects of polyozellin on endothelial protein C receptor shedding via inhibiting TACE activity and MAP kinases. Fitoterapia, 108: 26-32.
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  19. Lee, W., E.J. Park, S. Kwak, K.C. Lee, D.H. Na and J.S. Bae, 2016. Trimeric PEG-conjugated Exendin-4 for the treatment of sepsis. Biomacromolecules, 17: 1160-1169.
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  20. Lee, S.H., W. Lee, J.S. Bae and E. Ma, 2016. Synthesis and in vitro and in vivo anticoagulant and antiplatelet activities of amidino- and non-amidinobenzamides. Molecules, Vol. 21, No. 5. 10.3390/molecules21050676.
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  21. Lee, S., S.K. Ku and J.S. Bae, 2016. Anti-inflammatory effects of dabrafenib on polyphosphate-mediated vascular disruption. Chemico-Biol. Interact., 256: 266-273.
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  22. Lee, I.C. and J.S. Bae, 2016. Anti-inflammatory effects of vicenin-2 and scolymoside on polyphosphate-mediated vascular inflammatory responses. Inflamm. Res., 65: 203-212.
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  23. Lee, D., S. Lee, K.H. Liu, J.S. Bae, D.J. Baek and T. Lee, 2016. Solid-phase synthesis of 1,3,7,8-tetrasubstituted xanthine derivatives on traceless solid support. ACS Combinatorial Sci., 18: 70-74.
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  24. Ku, S.K., E.K. Yoon, W. Lee, S. Kwon, T. Lee and J.S. Bae, 2016. Antithrombotic and antiplatelet activities of pelargonidin in vivo and in vitro. Arch. Pharmacal Res., 39: 398-408.
    Direct Link  |  
  25. Ku, S.K., E.J. Yang, H. Kang, B. Jung and J.S. Bae, 2016. Inhibitory effect of polyozellin on secretory group IIA phospholipase A2. Arch. Pharmacal Res., 39: 271-278.
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  26. Ku, S.K. and J.S. Bae, 2016. Vicenin-2 and scolymoside inhibit high-glucose-induced vascular inflammation in vitro and in vivo. Can. J. Physiol. Pharmacol., 94: 287-295.
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  27. Kim, J., J. Kim and J.S. Bae, 2016. ROS homeostasis and metabolism: A critical liaison for cancer therapy. Exp. Mol. Med., Vol. 48. 10.1038/emm.2016.119.
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  28. Kim, J. and J.S. Bae, 2016. Tumor-associated macrophages and neutrophils in tumor microenvironment. Mediators Inflammation, Vol. 2016. 10.1155/2016/6058147.
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  29. Kang, H., T. Lee and J.S. Bae, 2016. Suppressive effects of pelargonidin on endothelial protein C receptor shedding via the inhibition of TACE activity and MAP kinases. Am. J. Chin. Med., 44: 771-784.
    CrossRef  |  Direct Link  |  
  30. Kang, H., S.K. Ku, H. Choi and J.S. Bae, 2016. Three diketopiperazines from marine-derived bacteria inhibit LPS-induced endothelial inflammatory responses. Bioorg. Med. Chem. Lett., 26: 1873-1876.
    CrossRef  |  Direct Link  |  
  31. Jung, B., S.K. Ku, M. Gao, K.M. Kim, M.S. Han, H. Choi and J.S. Bae, 2016. Suppressive effects of three diketopiperazines from marine-derived bacteria on TGFBIp-mediated septic responses in human endothelial cells and mice. Arch. Pharmacal Res., 39: 843-854.
    CrossRef  |  Direct Link  |  
  32. Jung, B., J. Kim and J.S. Bae, 2016. Dabrafenib, as a novel insight into drug repositioning against Secretory Group IIA phospholipase A2. Int. J. Pharmacol., 12: 415-421.
    CrossRef  |  
  33. Jung, B., J. Chung, W. Zhou, T. Lee, M. Na and J.S. Bae, 2016. Inhibitory effects of pentacyclic triterpenoids from Astilbe rivularis on TGFBIp-induced inflammatory responses in vitro and in vivo. Chem.-Biol. Interact., 254: 179-190.
    CrossRef  |  Direct Link  |  
  34. Jung, B., H. Kang, W. Lee, H.J. Noh and Y.S. Kim et al., 2016. Anti-septic effects of dabrafenib on HMGB1-mediated inflammatory responses. BMB Rep., 49: 214-219.
    CrossRef  |  Direct Link  |  
  35. Jung, B., E.J. Yang and J.S. Bae, 2016. Suppressive effects of polyozellin on TGFBIp-mediated septic responses in human endothelial cells and mice. Nutr. Res., 36: 380-389.
    CrossRef  |  Direct Link  |  
  36. Jeong, S., S.K. Ku, G. Min, H. Choi, D.H. Park and J.S. Bae, 2016. Suppressive effects of three diketopiperazines from marine-derived bacteria on polyphosphate-mediated septic responses. Chem.-Biol. Interact., 257: 61-70.
    CrossRef  |  Direct Link  |  
  37. Chung, J., S.K. Ku, S. Lee and J.S. Bae, 2016. Suppressive effects of lysozyme on polyphosphate-mediated vascular inflammatory responses. Biochem. Biophys. Res. Commun., 474: 715-721.
    CrossRef  |  Direct Link  |  
  38. Yoon, E.K., S.K. Ku, W. Lee, S. Kwak, H. Kang, B. Jung and J.S. Bae, 2015. Antitcoagulant and antiplatelet activities of scolymoside. BMB Rep., 48: 577-582.
    CrossRef  |  Direct Link  |  
  39. Yoo, H., S.K. Ku, W. Zhou, M.S. Han, M.K. Na and J.S. Bae, 2015. Anti-septic effects of phenolic glycosides from Rhododendron brachycarpum in vitro and in vivo. J. Funct. Foods, 16: 448-459.
    CrossRef  |  Direct Link  |  
  40. Yoo, H., S.K. Ku, S.W. Kim and J.S. Bae, 2015. Early diagnosis of sepsis using serum hemoglobin subunit Beta. Inflammation, 38: 394-399.
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  41. Yang, E.J., S.K. Ku, W. Lee, K.S. Song and J.S. Bae, 2015. Inhibitory effects of polyozellin from Polyozellus multiplex on HMGB1-mediated septic responses. Inflammation Res., 64: 733-746.
    CrossRef  |  Direct Link  |  
  42. Tuan, N.Q., W. Lee, J. Oh, S. Kwak and H.G. Lee et al., 2015. Quinic acid derivatives from Salicornia herbacea alleviate HMGB1-mediated endothelial dysfunction. J. Funct. Foods, 15: 326-338.
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  43. Tuan, N.Q., W. Lee, J. Oh, R.R. Kulkarni and C. Geny et al., 2015. Flavanones and chromones from Salicornia herbacea mitigate septic lethality via restoration of vascular barrier integrity. J. Agric. Food Chem., 63: 10121-10130.
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  44. Ryu, R., U.J. Jung, Y.R. Seo, H.J. Kim and B.S. Moon et al., 2015. Beneficial effect of persimmon leaves and bioactive compounds on thrombosis. Food Sci. Biotechnol., 24: 233-240.
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  45. Park, M.S., J.W. Kim, I. Park, H.K. Lee and C. Kim et al., 2015. Characterization of ticlopidine-induced developmental and teratogenic defects in Xenopus embryos and human endothelial cells. Chem. Biol. Interact., 240: 172-178.
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  46. Oh, S.Y., J.Y. Seok, Y.S. Choi, S.H. Lee, J.S. Bae and Y.M. Lee, 2015. The histone methyltransferase inhibitor BIX01294 inhibits HIF-1α stability and angiogenesis. Molecules Cells, 38: 528-534.
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  47. Lee, W., S.K. Ku, D.H. Na and J.S. Bae, 2015. Anti-inflammatory effects of lysozyme against HMGB1 in human endothelial cells and in mice. Inflammation, 38: 1911-1924.
    CrossRef  |  Direct Link  |  
  48. Lee, W., S.K. Ku and J.S. Bae, 2015. Antiplatelet, anticoagulant and profibrinolytic activities of baicalin. Arch. Pharm. Res., 38: 893-903.
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  49. Lee, W., S.K. Ku and J.S. Bae, 2015. Anti-inflammatory effects of Baicalin, Baicalein and Wogonin in vitro and in vivo. Inflammation, 38: 110-125.
    CrossRef  |  Direct Link  |  
  50. Lee, W., S.K. Ku and J.S. Bae, 2015. Ameliorative effect of vicenin-2 and olymoside on TGFBIp-induced septic responses. Inflammation, 38: 2166-2177.
    CrossRef  |  Direct Link  |  
  51. Lee, W., S. Kwak, H.S. Lee, D.H. Na, Y.M. Lee and J.S. Bae, 2015. Inhibitory effect of exendin-4 on secretory group IIA phospholipase A2. Biochem. Biophys. Res. Commun., 459: 650-654.
    CrossRef  |  Direct Link  |  
  52. Lee, W., S. Kwak, E. Yun, J.H. Lee, M. Na, G.Y. Song and J.S. Bae, 2015. Anti-septic effects of new 3’-N-substituted carbazole derivatives in vitro and in vivo. Inflammation, 38: 1649-1661.
  53. Lee, W., O.K. Kwon, M.S. Han, Y.M. Lee and S.W. Kim et al., 2015. Role of moesin in HMGB1-stimulated severe inflammatory responses. Thrombosis Haemostasis, 114: 350-363.
  54. Lee, W., K.M. Kim and J.S. Bae, 2015. Ameliorative effect of aspalathin and nothofagin from rooibos (Aspalathus linearis) on HMGB1-induced septic responses in vitro and in vivo. Am. J. Chinese Med., 43: 991-1012.
    CrossRef  |  Direct Link  |  
  55. Lee, W., J. Seo, S. Kwak, E.J. Park and D.H. Na et al., 2015. A double‐chambered protein nanocage loaded with thrombin receptor agonist peptide (TRAP) and γ‐carboxyglutamic acid of protein C (PC‐Gla) for sepsis treatment. Adv. Mater., 27: 6637-6643.
    CrossRef  |  Direct Link  |  
  56. Lee, W., E.K. Yoon, K.M. Kim, D.H. Park and J.S. Bae, 2015. Antiseptic effect of vicenin-2 and scolymoside from Cyclopia subternata (Honeybush) in response to HMGB1 as a late sepsis mediator in vitro and in vivo. Can. J. Physiol. Pharmacol., 93: 709-720.
    CrossRef  |  Direct Link  |  
  57. Lee, W., E.J. Park, S. Kwak, Y. Kim, D.H. Na and J.S. Bae, 2015. PEGylated lysozymes with anti-septic effects in human endothelial cells and in mice. Biochem. Biophys. Res. Commun., 459: 662-667.
    CrossRef  |  Direct Link  |  
  58. Lee, W. and J.S. Bae, 2015. Antithrombotic and antiplatelet activities of vicenin-2. Blood Coagulation Fibrinolysis, 26: 628-634.
    CrossRef  |  Direct Link  |  
  59. Lee, W. and J.S. Bae, 2015. Antithrombotic and antiplatelet activities of orientin in vitro and in vivo. J. Funct. Foods, 17: 388-398.
    CrossRef  |  Direct Link  |  
  60. Lee, W. and J.S. Bae, 2015. Anti-inflammatory effects of aspalathin and nothofagin from rooibos (Aspalathus linearis) in vitro and in vivo. Inflammation, 38: 1502-1516.
    CrossRef  |  Direct Link  |  
  61. Lee, S.H., J.G. Jee, J.S. Bae, K.H. Liu and Y.M. Lee, 2015. A group of novel HIF‐1α inhibitors, glyceollins, blocks HIF‐1α synthesis and decreases its stability via inhibition of the PI3K/AKT/mTOR pathway and Hsp90 binding. J. Cell. Physiol., 230: 853-862.
    CrossRef  |  Direct Link  |  
  62. Lee, I.C. and J.S. Bae, 2015. Inhibitory effect of vicenin-2 and scolymoside on secretory group IIA phospholipase A2. Anim. Cells Syst., 19: 305-311.
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  63. Lee, D.S., G.S. Jeong and J.S. Bae, 2015. Potential therapeutic properties of natural products through the expression of heme oxygenase-1. Mini-Rev. Organic Chem., 12: 455-463.
    Direct Link  |  
  64. Lee, D., D. Kim, S. Lee, T. Kim and J. Kim et al., 2015. Efficient syntheses of 1,2,3-triazoloamide derivatives using solid-and solution-phase synthetic approaches. Molecules, 20: 19984-20013.
    CrossRef  |  Direct Link  |  
  65. Kwon, O.K., W. Lee, S.J. Kim, Y.M. Lee and J.Y. Lee et al., 2015. In‐depth proteomics approach of secretome to identify novel biomarker for sepsis in LPS‐stimulated endothelial cells. Electrophoresis, 36: 2851-2858.
    CrossRef  |  Direct Link  |  
  66. Kwak, S., M.S. Han and J.S. Bae, 2015. Aspalathin and nothofagin from rooibos (Aspalathus linearis) inhibit endothelial protein C receptor shedding in vitro and in vivo. Fitoterapia, 100: 179-186.
    CrossRef  |  Direct Link  |  
  67. Kulkarnia, R.R., W. Lee, T.S. Jang, J. Lee and S. Kwak et al., 2015. Caffeoyl glucosides from Nandina domestica inhibit LPS-induced endothelial inflammatory responses. Bioorg. Med. Chem. Lett., 25: 5367-5371.
    CrossRef  |  Direct Link  |  
  68. Ku, S.K., W. Zhou, W. Lee, M.S. Han, M.K. Na and J.S. Bae, 2015. Anti-inflammatory effects of hyperoside in human endothelial cells and in mice. Inflammation, 38: 784-799.
    CrossRef  |  Direct Link  |  
  69. Ku, S.K., W. Lee, M. Kang and J.S. Bae, 2015. Antithrombotic activities of aspalathin and nothofagin via inhibiting platelet aggregation and FIIa/FXa. Arch. Pharm. Res., 38: 1080-1089.
    CrossRef  |  Direct Link  |  
  70. Ku, S.K., S. Kwak, Y. Kim and J.S. Bae, 2015. Aspalathin and nothofagin from rooibos (Aspalathus linearis) inhibits high glucose-induced inflammation in vitro and in vivo. Inflammation, 38: 445-455.
    CrossRef  |  Direct Link  |  
  71. Ku, S.K., M.C. Baek and J.S. Bae, 2015. Anti-inflammatory effects of methylthiouracil in vitro and in vivo. Toxicol. Applied Pharmacol., 288: 374-386.
    CrossRef  |  Direct Link  |  
  72. Ku, S.K., J.H. Lee, O. Yuseok, W. Lee, G.Y. Song and J.S. Bae, 2015. Vascular barrier protective effects of 3-N-or 3-O-cinnamoyl carbazole derivatives. Bioorg. Med. Chem. Lett., 25: 4304-4307.
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  73. Ku, S.K., H.G. Lee and J.S. Bae, 2015. Inhibitory effect of baicalin, baicalein and wogonin on secretory group IIA phospholipase A2. Arch. Pharm. Res., 38: 1865-1872.
    CrossRef  |  Direct Link  |  
  74. Ku, S.K., E.K. Yoon, H.G. Lee, M.S. Han, T. Lee and J.S. Bae, 2015. Inhibitory effects of lysozyme on endothelial protein C 1receptor shedding in vitro and in vivo. BMB Rep., 48: 624-629.
    CrossRef  |  Direct Link  |  
  75. Ku, S.K. and J.S. Bae, 2015. Inhibitory effect of FXa on secretory group IIA phospholipase A2. Inflammation, 38: 987-994.
    CrossRef  |  Direct Link  |  
  76. Ku, S.K. and J.S. Bae, 2015. Baicalin, baicalein and wogonin inhibits high glucose-induced vascular inflammation in vitro and in vivo. BMB Rep., 48: 519-524.
    CrossRef  |  Direct Link  |  
  77. Kim, D., D.J. Baek, D. Lee, K.H. Liu and J.S. Bae et al., 2015. Efficient solid-phase synthesis of 2,4-disubstituted 5-carbamoyl-thiazole derivatives using a traceless support. Tetrahedron, 71: 3367-3377.
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  78. Kang, H., S.K. Ku, B. Jung and J.S. Bae, 2015. Anti-inflammatory effects of vicenin-2 and scolymoside in vitro and in vivo. Inflammation Res., 64: 1005-1021.
    CrossRef  |  Direct Link  |  
  79. Jung, B., S.K. Ku and J.S. Bae, 2015. Ameliorative effect of methylthiouracil on TGFBIp-induced septic responses. Biochem. Biophys. Res. Commun., 463: 661-666.
    CrossRef  |  Direct Link  |  
  80. Hwang, G.H., Y.J. Jeon, H.J. Han, S.H. Park and K.M. Baek et al., 2015. Protective effect of butylated hydroxylanisole against hydrogen peroxide-induced apoptosis in primary cultured mouse hepatocytes. J. Vet. Sci., 16: 17-23.
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  81. Hwang, G.H., J.M. Ryu, Y.J. Jeon, J. Choi and H.J. Han et al., 2015. The role of thioredoxin reductase and glutathione reductase in plumbagin-induced, reactive oxygen species-mediated apoptosis in cancer cell lines. Eur. J. Pharmacol., 765: 384-393.
  82. Baek, M.C., B. Jung, H. Kang, H.S. Lee and J.S. Bae, 2015. Novel insight into drug repositioning: Methylthiouracil as a case in point. Pharmacol. Res., 99: 185-193.
    CrossRef  |  Direct Link  |  
  83. Bae, J.S., 2015. Inhibitory effect of orientin on secretory group IIA phospholipase A2. Inflammation, 38: 1631-1638.
    CrossRef  |  Direct Link  |  
  84. Zhou, W., J. Oh, W. Lee, S. Kwak and W. Li et al., 2014. The first cyclomegastigmane rhododendroside A from Rhododendron brachycarpum alleviates HMGB1-induced sepsis. Biochim. Biophys. Acta-Gen. Subjects, 1840: 2042-2049.
    CrossRef  |  Direct Link  |  
  85. Yoo, H., S.K. Ku, Y.D. Baek and J.S. Bae, 2014. Anti-inflammatory effects of rutin on HMGB1-induced inflammatory responses in vitro and in vivo. Inflammation Res., 63: 197-206.
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  86. Yoo, H., S.K. Ku, W. Lee, S. Kwak and Y.D. Baek et al., 2014. Antiplatelet, anticoagulant, and profibrinolytic activities of cudratricusxanthone A. Arch. Pharm. Res., 37: 1069-1078.
    CrossRef  |  Direct Link  |  
  87. Yoo, H., S.K. Ku, T. Lee and J.S. Bae, 2014. Orientin inhibits HMGB1-induced inflammatory responses in HUVECs and in murine polymicrobial sepsis. Inflammation, 37: 1705-1717.
    CrossRef  |  Direct Link  |  
  88. Yoo, H., S.K. Ku, M.S. Han, K.M. Kim and J.S. Bae, 2014. Anti-septic effects of fisetin in vitro and in vivo. Inflammation, 37: 1560-1574.
    CrossRef  |  Direct Link  |  
  89. Song, M., J.Y. Hwang, M.Y. Lee, J.G. Jee and Y.M. Lee et al., 2014. In vitro inhibitory effect of piperlonguminine isolated from Piper longum on human cytochrome P450 1A2. Arch. Pharm. Res., 37: 1063-1068.
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  90. Song, M., H. Do, O.K. Kwon, E.J. Yang and J.S. Bae et al., 2014. A comparison of the in vitro inhibitory effects of thelephoric acid and SKF-525A on human cytochrome P450 activity. Biomolecules Therapeutics, 22: 155-160.
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  91. Song, M., D. Lee, J.S. Bae, J. Lee, Y.D. Gong, T. Lee and S. Lee, 2014. Identification of Metabolites of N-(5-Benzoyl-2-(4-(2-Methoxyphenyl) piperazin-1-yl)thiazol-4-yl) pivalamide including CYP3A4-Mediated C-demethylation in human liver microsomes with high-resolution/high-accuracy tandem mass. Drug Metab. Disposition, 42: 1252-1260.
  92. Son, J., M.S. Park, I. Park, H.K. Lee and S.H. Lee et al., 2014. Pick1 modulates ephrinB1-induced junctional disassembly through an association with ephrinB1. Biochem. Biophys. Res. Commun., 450: 659-665.
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  93. Shin, S.H., S. Lee, J.S. Bae, J.G. Jee, H.J. Cha and Y.M. Lee, 2014. Thymosin beta4 regulates cardiac valve formation via endothelial-mesenchymal transformation in zebrafish embryos. Mol. Cells, 37: 330-336.
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  94. Lee, W., S.K. Ku, Y.M. Lee and J.S. Bae, 2014. Anti-septic effects of glyceollins in HMGB1-induced inflammatory responses in vitro and in vivo. Food Chem. Toxicol., 63: 1-8.
    CrossRef  |  Direct Link  |  
  95. Lee, W., S.K. Ku, T.C. Jeong, S. Lee and J.S. Bae, 2014. Ginsenosides Inhibit HMGB1-induced Inflammatory Responses in HUVECs and in murine polymicrobial sepsis. Bull. Korean Chem. Soc., 35: 2955-2962.
  96. Lee, W., S.K. Ku, S.W. Kim and J.S. Bae, 2014. Endocan elicits severe vascular inflammatory responses in vitro and in vivo. J. Cell. Physiol., 229: 620-630.
    CrossRef  |  Direct Link  |  
  97. Lee, W., S.K. Ku, E.J. Park, D.H. Na, K.M. Kim and J.S. Bae, 2014. Exendin-4 inhibits HMGB1-induced inflammatory responses in HUVECs and in murine polymicrobial sepsis. Inflammation, 37: 1876-1888.
    CrossRef  |  Direct Link  |  
  98. Lee, W., S.K. Ku, D. Lee, T. Lee and J.S. Bae, 2014. Emodin-6-O-β-D--glucoside inhibits high-glucose-induced vascular inflammation. Inflammation, 37: 306-313.
    CrossRef  |  Direct Link  |  
  99. Lee, W., S.K. Ku, B.W. Min, S. Lee, J.G. Jee, J.A. Kim and J.S. Bae, 2014. Vascular barrier protective effects of pellitorine in LPS-induced inflammation in vitro and in vivo. Fitoterapia, 92: 177-187.
    CrossRef  |  Direct Link  |  
  100. Lee, W., S.K. Ku and J.S. Bae, 2014. Vascular barrier protective effects of orientin and isoorientin in LPS-induced inflammation in vitro and in vivo. Vascular Pharmacol., 62: 3-14.
    CrossRef  |  Direct Link  |  
  101. Lee, W., S.K. Ku and J.S. Bae, 2014. Factor Xa inhibits HMGB1-induced septic responses in human umbilical vein endothelial cells and in mice. Thrombosis Haemostasis, 112: 757-769.
    CrossRef  |  Direct Link  |  
  102. Lee, W., S. Ku, H. Yoo, K. Song and J. Bae, 2014. Andrographolide inhibits HMGB1‐induced inflammatory responses in human umbilical vein endothelial cells and in murine polymicrobial sepsis. Acta Physiol., 211: 176-187.
    CrossRef  |  Direct Link  |  
  103. Lee, W., H. Yoo, S.K. Ku, S.W. Kim and J.S. Bae, 2014. Raftlin: A new biomarker in human sepsis. Inflammation, 37: 706-711.
    CrossRef  |  Direct Link  |  
  104. Lee, H.G., H.Y. Choi and J.S. Bae, 2014. Endocan as a potential diagnostic or prognostic biomarker for chronic kidney disease. Kidney Int., 86: 1079-1081.
    CrossRef  |  Direct Link  |  
  105. Kwak, S., S.K. Ku, M.S. Han and J.S. Bae, 2014. Vascular barrier protective effects of baicalin, baicalein and wogonin in vitro and in vivo. Toxicol. Applied Pharmacol., 281: 30-38.
    CrossRef  |  Direct Link  |  
  106. Kwak, S., S.K. Ku and J.S. Bae, 2014. Fisetin inhibits high-glucose-induced vascular inflammation in vitro and in vivo. Inflammation Res., 63: 779-787.
    CrossRef  |  Direct Link  |  
  107. Ku, S.K., S. Kwak, O.J. Kwon and J.S. Bae, 2014. Hyperoside inhibits high-glucose-induced vascular inflammation in vitro and in vivo. Inflammation, 37: 1389-1400.
    CrossRef  |  Direct Link  |  
  108. Ku, S.K., S. Kwak and J.S. Bae, 2014. Orientin inhibits high glucose-induced vascular inflammation in vitro and in vivo. Inflammation, 37: 2164-2173.
    CrossRef  |  Direct Link  |  
  109. Ku, S.K., M.S. Han, M.Y. Lee, Y.M. Lee and J.S. Bae, 2014. Inhibitory effects of oroxylin a on endothelial protein c receptor shedding in vitro and in vivo. BMB Rep., 47: 336-341.
    CrossRef  |  Direct Link  |  
  110. Ku, S.K., M.S. Han, G.S. Jeong and J.S. Bae, 2014. Cudratricusxanthone A inhibits endothelial protein C receptor shedding in vitro and in vivo. Anim. Cells Syst., 18: 9-16.
    CrossRef  |  Direct Link  |  
  111. Ku, S.K., M.S. Han, E.J. Park, D.H. Na and J.S. Bae, 2014. Exendin-4 inhibits endothelial protein C receptor shedding in vitro and in vivo. Pharmacol. Res., 84: 18-25.
    CrossRef  |  Direct Link  |  
  112. Ku, S.K., M.S. Han and J.S. Bae, 2014. Withaferin A is an inhibitor of endothelial protein C receptor shedding in vitro and in vivo. Food Chem. Toxicol., 68: 23-29.
    CrossRef  |  Direct Link  |  
  113. Ku, S.K., M.S. Han and J.S. Bae, 2014. Sulforaphane inhibits endothelial protein C receptor shedding in vitro and in vivo. Vascular Pharmacol., 63: 13-18.
    CrossRef  |  Direct Link  |  
  114. Ku, S.K., J.A. Kim and J.S. Bae, 2014. Vascular barrier protective effects of piperlonguminine in vitro and in vivo. Inflammation Res., 63: 369-379.
    CrossRef  |  Direct Link  |  
  115. Ku, S.K., J.A. Kim and J.S. Bae, 2014. Piperlonguminine downregulates endothelial protein C receptor shedding in vitro and in vivo. Inflammation, 37: 435-442.
    CrossRef  |  Direct Link  |  
  116. Ku, S.K., I.C. Lee, M.S. Han and J.S. Bae, 2014. Inhibitory effects of rutin on the endothelial protein C receptor shedding in vitro and in vivo. Inflammation, 37: 1424-1431.
    CrossRef  |  Direct Link  |  
  117. Ku, S.K., I.C. Lee, J.A. Kim and J.S. Bae, 2014. Anti-septic effects of pellitorine in HMGB1-induced inflammatory responses in vitro and in vivo. Inflammation, 37: 338-348.
    CrossRef  |  Direct Link  |  
  118. Ku, S.K., H. Yoo, W. Zhou, M.K. Na and J.S. Bae, 2014. Antiplatelet activities of hyperoside in vitro and in vivo. Anim. Cells Syst., 18: 204-209.
    CrossRef  |  Direct Link  |  
  119. Ku, S.K. and J.S. Bae, 2014. Antithrombotic activities of wogonin and wogonoside via inhibiting platelet aggregation. Fitoterapia, 98: 27-35.
    CrossRef  |  Direct Link  |  
  120. Ku, S.K. and J.S. Bae, 2014. Antithrombotic activities of sulforaphane via inhibiting platelet aggregation and FIIa/FXa. Pharm. Res., 37: 1454-1463.
    CrossRef  |  Direct Link  |  
  121. Ku, S.K. and J.S. Bae, 2014. Antiplatelet, anticoagulant and profibrinolytic activities of withaferin A. Vascular Pharmacol., 60: 120-126.
    CrossRef  |  Direct Link  |  
  122. Ku, S.K. and J.S. Bae, 2014. Antiplatelet and antithrombotic activities of purpurogallin in vitro and in vivo. BMB Rep., 47: 376-381.
    CrossRef  |  Direct Link  |  
  123. Jeong, G.S. and J.S. Bae, 2014. Anti-inflammatory effects of triterpenoids: Naturally occurring and synthetic agents. Mini-Rev. Organic Chem., 11: 316-329.
    Direct Link  |  
  124. Bae, J.S., W. Lee, J.O. Nam, J.E. Kim, S.W. Kim and I.S. Kim, 2014. Transforming growth factor β-induced protein promotes severe vascular inflammatory responses. Am. J. Respiratory Critical Care Med., 189: 779-786.
    CrossRef  |  Direct Link  |  
  125. Bae, J.S., W. Lee, H.N. Son, Y.M. Lee and I.S. Kim, 2014. Anti‐transforming growth factor β‐induced protein antibody ameliorates vascular barrier dysfunction and improves survival in sepsis. Acta Physiol., 212: 306-315.
    CrossRef  |  Direct Link  |  
  126. Ku, S.K., I.C. Lee and J.S. Bae, 2014. Antithrombotic activities of oroxylin A in vitro and in vivo. Arch. Pharm. Res., 37: 679-686.
    CrossRef  |  Direct Link  |  
  127. Yoo, H., H.S. Lee, W. Lee and J.S. Bae, 2013. Effects of lycopene on endothelial protein C receptor shedding in vitro and in vivo. J. Life Sci., 23: 650-656.
    CrossRef  |  Direct Link  |  
  128. Yang, E.J., S.K. Ku, W. Lee, S. Lee, T. Lee, K.S. Song and J.S. Bae, 2013. Barrier protective effects of rosmarinic acid on HMGB1‐induced inflammatory responses in vitro and in vivo. J. Cell. Physiol., 228: 975-982.
    CrossRef  |  Direct Link  |  
  129. Song, M., M. Hong, M.Y. Lee, J.G. Jee and Y.M. Lee et al., 2013. Selective inhibition of the cytochrome P450 isoform by hyperoside and its potent inhibition of CYP2D6. Food Chem. Toxicol., 59: 549-553.
    CrossRef  |  Direct Link  |  
  130. Ryu, R., U.J. Jung, H.J. Kim, W. Lee, J.S. Bae, Y.B. Park and M.S. Choi, 2013. Anticoagulant and antiplatelet activities of Artemisia princeps Pampanini and its bioactive components. Prev. Nutr. Food Sci., 18: 181-187.
    CrossRef  |  Direct Link  |  
  131. Lee, W., S.K. Ku, T.H. Kim and J.S. Bae, 2013. Emodin-6-O-β-d-glucoside inhibits HMGB1-induced inflammatory responses in vitro and in vivo. Food Chem. Toxicol., 52: 97-104.
    CrossRef  |  Direct Link  |  
  132. Lee, W., S.K. Ku, J.A. Kim, T. Lee and J.S. Bae, 2013. Inhibitory effects of epi-sesamin on HMGB1-induced vascular barrier disruptive responses in vitro and in vivo. Toxicol. Applied Pharmacol., 267: 201-208.
    CrossRef  |  Direct Link  |  
  133. Lee, W., S.K. Ku and J.S. Bae, 2013. Emodin-6-O-β-d-glucoside down-regulates endothelial protein C receptor shedding. Arch. Pharm. Res., 36: 1160-1165.
    CrossRef  |  Direct Link  |  
  134. Lee, W., H. Yoo, S.K. Ku, J.A. Kim and J.S. Bae, 2013. Anticoagulant activities of piperlonguminine in vitro and in vivo. BMB Rep., 46: 484-489.
    CrossRef  |  Direct Link  |  
  135. Lee, W., H. Yoo, J.A. Kim, S. Lee and J.G. Jee et al., 2013. Barrier protective effects of piperlonguminine in LPS-induced inflammation in vitro and in vivo. Food Chem. Toxicol., 58: 149-157.
    CrossRef  |  Direct Link  |  
  136. Lee, W., E.J. Yang, S.K. Ku, K.S. Song and J.S. Bae, 2013. Anti-inflammatory effects of oleanolic acid on LPS-induced inflammation in vitro and in vivo. Inflammation, 36: 94-102.
  137. Lee, D., Y.H. Seo, J.S. Bae, S. Lee, T.I. Lee, Y.D. Gong and T. Lee, 2013. An efficient and regioselective synthesis of 2, 3-disubstituted 6-aminoquinoxaline derivatives using alkoxylation and microwave-assisted sonogashira coupling. Notes, 34: 2522-2524.
  138. Kwon, O.J., J.S. Bae, H.Y. Lee, J.Y. Hwang, E.W. Lee, H. Ito and T.H. Kim, 2013. Pancreatic lipase inhibitory gallotannins from galla rhois with inhibitory effects on adipocyte differentiation in 3T3-L1 cells. Molecules, 18: 10629-10638.
    CrossRef  |  Direct Link  |  
  139. Ku, S.K., W. Lee, H. Yoo, C.K. Han and J.S. Bae, 2013. Inhibitory effects of epi-sesamin on endothelial protein C receptor shedding in vitro and in vivo. Inflammation Res., 62: 895-902.
    CrossRef  |  Direct Link  |  
  140. Ku, S.K., T.H. Kim, S. Lee, S.M. Kim and J.S. Bae, 2013. Antithrombotic and profibrinolytic activities of isorhamnetin-3-O-galactoside and hyperoside. Food Chem. Toxicol., 53: 197-204.
    CrossRef  |  Direct Link  |  
  141. Ku, S.K., T.H. Kim and J.S. Bae, 2013. Anticoagulant activities of persicarin and isorhamnetin. Vascular Pharmacol., 58: 272-279.
    CrossRef  |  Direct Link  |  
  142. Ku, S.K., M.S. Han and J.S. Bae, 2013. Down-regulation of endothelial protein C receptor shedding by persicarin and isorhamnetin-3-O-galactoside. Thrombosis Res., 132: e58-e63.
    CrossRef  |  Direct Link  |  
  143. Ku, S.K., J.A. Kim, C.K. Han and J.S. Bae, 2013. Antithrombotic activities of epi-sesamin in vitro and in vivo. Am. J. Chin. Med., 41: 1313-1327.
    CrossRef  |  Direct Link  |  
  144. Ku, S.K., I.C. Lee, J.A. Kim and J.S. Bae, 2013. Antithrombotic activities of pellitorine in vitro and in vivo. Fitoterapia, 91: 1-8.
    CrossRef  |  
  145. Ku, S.K., I.C. Lee and J.S. Bae, 2013. Inhibitory effects of purpurogallin on the endothelial protein C receptor shedding in vitro and in vivo. J. Korean Soc. Applied Biol. Chem., 56: 519-524.
    CrossRef  |  Direct Link  |  
  146. Ku, S.K., E.J. Yang, K.S. Song and J.S. Bae, 2013. Rosmarinic acid down-regulates endothelial protein C receptor shedding in vitro and in vivo. Food Chem. Toxicol., 59: 311-315.
    CrossRef  |  Direct Link  |  
  147. Ku, S.K. and J.S. Bae, 2013. Concentration dependent anti-inflammatory effects thrombin on polyphosphate-mediated inflammatory responses in vitro and in vivo. Inflamm. Res., 62: 609-616.
    CrossRef  |  Direct Link  |  
  148. Kim, T.H., S.K. Ku and J.S. Bae, 2013. Persicarin is anti‐inflammatory mediator against HMGB1‐induced inflammatory responses in HUVECs and in CLP‐induced sepsis mice. J. Cell. Physiol., 228: 696-703.
    CrossRef  |  Direct Link  |  
  149. Kim, T.H., S.K. Ku and J.S. Bae, 2013. Anti‐inflammatory activities of isorhamnetin‐3‐O‐galactoside against HMGB1‐induced inflammatory responses in both HUVECs and CLP‐induced septic mice. J. Cell. Biochem., 114: 336-345.
    CrossRef  |  Direct Link  |  
  150. Kim, M., J. Son, M.S. Park, Y. Ji and S. Chae et al., 2013. In vivo evaluation and comparison of developmental toxicity and teratogenicity of perfluoroalkyl compounds using Xenopus embryos. Chemosphere, 93: 1153-1160.
    CrossRef  |  Direct Link  |  
  151. Choi, J.H., M.P. Nguyen, S.Y. Jung, S.M. Kwon and J.G. Jee et al., 2013. Inhibitory effect of glyceollins on vasculogenesis through suppression of endothelial progenitor cell function. Mol. Nutr. Food Res., 57: 1762-1771.
    CrossRef  |  Direct Link  |  
  152. Bae, J.S. and A.R. Rezaie, 2013. Thrombin inhibits HMGB1-mediated proinflammatory signaling responses when endothelial protein C receptor is occupied by its natural ligand. BMB Rep., 46: 544-549.
    CrossRef  |  Direct Link  |  
  153. Yang, E.J., W. Lee, S.K. Ku, K.S. Song and J.S. Bae, 2012. Anti-inflammatory activities of oleanolic acid on HMGB1 activated HUVECs. Food Chem. Toxicol., 50: 1288-1294.
    CrossRef  |  Direct Link  |  
  154. Min, K.J., J.S. Bae and T.K. Kwon, 2012. Effect of Activated Protein C (APC) on apoptosis of cancer cells. J. Life Sci., 22: 679-701.
    CrossRef  |  Direct Link  |  
  155. Lee, W.H., E.J. Yang, S.K. Ku, K.S. Song and J.S. Bae, 2012. Anticoagulant activities of oleanolic acid via inhibition of tissue factor expressions. BMB Rep., 45: 390-395.
    CrossRef  |  Direct Link  |  
  156. Lee, W., T.H. Kim, S.K. Ku, K.J. Min, H.S. Lee, T.K. Kwon and J.S. Bae, 2012. Barrier protective effects of withaferin A in HMGB1-induced inflammatory responses in both cellular and animal models. Toxicol. Applied Pharmacol., 262: 91-98.
    CrossRef  |  Direct Link  |  
  157. Lee, W., S.K. Ku, J.W. Bae and J.S. Bae, 2012. Inhibitory effects of lycopene on HMGB1-mediated pro-inflammatory responses in both cellular and animal models. Food Chem. Toxicol., 50: 1826-1833.
    CrossRef  |  Direct Link  |  
  158. Lee, W., S.K. Ku and J.S. Bae, 2012. Barrier protective effects of rutin in LPS-induced inflammation in vitro and in vivo. Food Chem. Toxicol., 50: 3048-3055.
    CrossRef  |  Direct Link  |  
  159. Kim, T.H., T. Lee, S.K. Ku and J.S. Bae, 2012. Vascular barrier protective effects of eckol and its derivatives. Bioorg. Med. Chem. Lett., 22: 3710-3712.
    CrossRef  |  Direct Link  |  
  160. Kim, T.H., S.K. Ku, T. Lee and J.S. Bae, 2012. Vascular barrier protective effects of phlorotannins on HMGB1-mediated proinflammatory responses in vitro and in vivo. Food Chem. Toxicol., 50: 2188-2195.
    CrossRef  |  Direct Link  |  
  161. Kim, T.H., S.K. Ku, I.C. Lee and J.S. Bae, 2012. Anti-inflammatory functions of purpurogallin in LPS-activated human endothelial cells. BMB Rep., 45: 200-205.
    CrossRef  |  Direct Link  |  
  162. Kim, T.H., S.K. Ku, I.C. Lee and J.S. Bae, 2012. Anti-inflammatory effects of kaempferol-3-O-sophoroside in human endothelial cells. Inflamm. Res., 61: 217-224.
    CrossRef  |  Direct Link  |  
  163. Kim, T.H., S.K. Ku and J.S. Bae, 2012. Inhibitory effects of kaempferol-3-O-sophoroside on HMGB1-mediated proinflammatory responses. Food Chem. Toxicol., 50: 1118-1123.
    CrossRef  |  Direct Link  |  
  164. Kim, T.H., S.K. Ku and J.S. Bae, 2012. Effects of (-)-epigallocatechin gallate on HMGB1 and interleukin-1β-mediated barrier disruption in human endothelial cells. J. Korean Soc. Applied Biol. Chem., 55: 165-173.
    CrossRef  |  Direct Link  |  
  165. Kim, T.H., S.K. Ku and J.S. Bae, 2012. Antithrombotic and profibrinolytic activities of eckol and dieckol. J. Cell. Biochem., 113: 2877-2883.
    CrossRef  |  Direct Link  |  
  166. Kim, T.H. and J.S. Bae, 2012. Inhibitory effects of lycopene on the expression of pro-inflammatory genes in human vascular endothelial cells. Korean J. Food Preserv., 19: 287-293.
    CrossRef  |  Direct Link  |  
  167. Kim, D.C., S.K. Ku, W. Lee and J.S. Bae, 2012. Barrier protective activities of curcumin and its derivative. Inflamm. Res., 61: 437-444.
    CrossRef  |  Direct Link  |  
  168. Kim, D.C., S.K. Ku and J.S. Bae, 2012. Anticoagulant activities of curcumin and its derivative. BMB Rep., 45: 221-226.
    CrossRef  |  Direct Link  |  
  169. Bae, J.S., W. Lee and A.R. Rezaie, 2012. Polyphosphate elicits pro-inflammatory responses that are counteracted by activated protein C in both cellular and animal models. J. Thrombosis Haemostasis, 10: 1145-1151.
    CrossRef  |  Direct Link  |  
  170. Bae, J.S., H.S. Lee, H.Y. Lee, B.H. Yoo, T. Kim, Y.H. Kim and T.H. Kim, 2012. Evaluation of acetylcholinesterase inhibitory and antioxidative activities of Rhus javanica. Korean J. Food Preserv., 19: 751-756.
    CrossRef  |  Direct Link  |  
  171. Bae, J.S., 2012. Role of high mobility group box 1 in inflammatory disease: Focus on sepsis. Arch. Pharm. Res., 35: 1511-1523.
    CrossRef  |  Direct Link  |  
  172. Bae, J.S., 2012. Effects of lower concentration thrombin on high-mobility group box 1 protein-mediated inflammatory responses. Inflammation, 35: 1078-1086.
    CrossRef  |  Direct Link  |  
  173. Bae, J.S., 2012. Barrier protective activities of phloroglucinol on lipopolysaccharide (LPS)-induced barrier disruption in human endothelial cells. Inflammation, 35: 920-926.
    CrossRef  |  Direct Link  |  
  174. Bae, J.S. and T.H. Kim, 2012. Enzymatic transformation of caffeic acid with enhanced cyclooxygenase-2 inhibitory activity. Bioorg. Med. Chem. Lett., 22: 793-796.
    CrossRef  |  Direct Link  |  
  175. Lee, I.C., J.S. Bae, T. Kim, O.J. Kwon and T.H. Kim, 2011. Polyphenolic constituents from the aerial parts of Thymus quinquecostatus var. japonica collected on Ulleung Island. J. Korean Soc. Applied Biol. Chem., 54: 811-816.
    CrossRef  |  Direct Link  |  
  176. Kim, D.C., W. Lee and J.S. Bae, 2011. Vascular anti-inflammatory effects of curcumin on HMGB1-mediated responses in vitro. Inflamm. Res., 60: 1161-1168.
    CrossRef  |  Direct Link  |  
  177. Bae, J.W. and J.S. Bae, 2011. Barrier protective effects of lycopene in human endothelial cells. Inflamm. Res., 60: 751-758.
    CrossRef  |  Direct Link  |  
  178. Bae, J.S., 2011. Inhibitory effect of thrombin on the expression of secretory group IIA phospholipase A2. J. Cell. Biochem., 112: 2502-2507.
    CrossRef  |  Direct Link  |  
  179. Bae, J.S., 2011. Antithrombotic and profibrinolytic activities of phloroglucinol. Food Chem. Toxicol., 49: 1572-1577.
    CrossRef  |  Direct Link  |  
  180. Bae, J.S. and T.H. Kim, 2011. Pancreatic lipase inhibitory and antioxidant activities of Zingiber officinale extracts. Korean J. Food Preserv., 18: 390-396.
    CrossRef  |  Direct Link  |  
  181. Bae, J.S. and A.R. Rezaie, 2011. Activated protein c inhibits high mobility group box 1 signaling in endothelial cells. Blood, 118: 3952-3959.
    CrossRef  |  Direct Link  |  
  182. Kim, T.H. and J.S. Bae, 2010. Inhibitory effects of antithrombin on the expression of secretory group IIA phospholipase A2 in endothelial cells. BMB Rep., 43: 604-608.
    CrossRef  |  Direct Link  |  
  183. Kim, T.H. and J.S. Bae, 2010. Ecklonia cava extracts inhibit lipopolysaccharide induced inflammatory responses in human endothelial cells. Food Chem. Toxicol., 48: 1682-1687.
    CrossRef  |  Direct Link  |  
  184. Hong, J.Y., S.R. Shin, M.J. Bae, J.S. Bae and I.C. Lee et al., 2010. Pancreatic lipase inhibitors isolated from the leaves of cultivated mountain ginseng (Panax ginseng). Korean J. Food Preserv., 17: 727-732.
    Direct Link  |  
  185. Cho, C.H., J.S. Bae and Y.U. Kim, 2010. 5α-reductase inhibitory components as antiandrogens from herbal medicine. J. Acupuncture Meridian Stud., 3: 116-118.
    CrossRef  |  Direct Link  |  
  186. Bae, J.S., Y.U. Kim and M.K. Park, 2010. A study on the concentration of aflatoxin B1 in granule and globular types of herbal medicines. J. Environ. Sci. Int., 19: 209-215.
    CrossRef  |  Direct Link  |  
  187. Bae, J.S., L. Yang and A.R. Rezaie, 2010. Factor X/Xa elicits protective signaling responses in endothelial cells directly via PAR-2 and indirectly via endothelial protein C receptor-dependent recruitment of PAR-1. J. Biol. Chem., 285: 34803-34812.
    CrossRef  |  Direct Link  |  
  188. Bae, J.S., J.P. Park, Y.U. Kim and M.K. Park, 2010. Concentration of heavy metals in granule, globular and liquid types of herbal medicines. KSBB J., 25: 91-96.
    Direct Link  |  
  189. Bae, J.S., I.S. Kim and A.R. Rezaie, 2010. Thrombin down-regulates the TGF-β-mediated synthesis of collagen and fibronectin by human proximal tubule epithelial cells through the EPCR-dependent activation of PAR-1. J. Cell. Physiol., 225: 233-239.
    CrossRef  |  Direct Link  |  
  190. Bae, J.S. and M.K. Park, 2010. Effect of thrombin on the TNF-α induced IL-6 production in HUVECs. KSBB J., 25: 11-17.
    Direct Link  |  
  191. Bae, J.S. and A.R. Rezaie, 2010. Thrombin upregulates the angiopoietin-Tie2 Axis: endothelial protein C receptor occupancy prevents the thrombin mobilization of angiopoietin 2 and P-selectin from Weibel-Palade bodies. J. Thrombosis Haemostasis, 8: 1107-1115.
    CrossRef  |  Direct Link  |  
  192. Bae, J.S. and A.R. Rezaie, 2010. Thrombin and activated protein C inhibit the expression of secretory group IIA phospholipase A2 in the TNF-α-activated endothelial cells by EPCR and PAR-1 dependent mechanisms. Thrombosis Res., 125: e9-e15.
    CrossRef  |  Direct Link  |  
  193. Javed, A., F. Afzal, J.S. Bae, S. Gutierrez and K. Zaidi et al., 2009. Specific residues of RUNX2 are obligatory for formation of BMP2-induced RUNX2-SMAD complex to promote osteoblast differentiation. Cells Tissues Org., 189: 133-137.
    CrossRef  |  Direct Link  |  
  194. Ha, J.L., J.S. Bae, M.K. Park, Y.U. Kim and S.H. Ha et al., 2009. Quantitative analysis of carotenoids in carrot cultivars produced in Korea. J. Environ. Sci. Int., 18: 1135-1141.
    CrossRef  |  Direct Link  |  
  195. Bae, J.S., Y.U. Kim, M.K. Park and A.R. Rezaie, 2009. Concentration dependent dual effect of thrombin in endothelial cells via Par-1 and Pi3 kinase. J. Cell. Physiol., 219: 744-751.
    CrossRef  |  Direct Link  |  
  196. Bae, J.S., M.K. Park and S.W. Park, 2009. Effect of soluble EPCR on the anti-inflammatory effects by activated protein C. Korean Chem. Eng. Res., 47: 501-505.
    Direct Link  |  
  197. Bae, J.S. and T.H. Kim, 2009. Acetylcholinesterase inhibitory and antioxidant properties of Aster yomena extract. Korea J. Herbol., 24: 121-126.
    Direct Link  |  
  198. Bae, J.S. and A.R. Rezaie, 2009. Thrombin inhibits nuclear factor κB and RhoA pathways in cytokine-stimulated vascular endothelial cells when EPCR is occupied by protein C. Thrombosis Haemostasis, 101: 513-520.
    Direct Link  |  
  199. Bae, J.S. and A.R. Rezaie, 2009. Mutagenesis studies toward understanding the intracellular signaling mechanism of antithrombin. J. Thrombosis Haemostasis, 7: 803-810.
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  200. Rezaie, A.R., J.S. Bae, C. Manithody, S.H. Qureshi and L. Yang, 2008. Protein Z-dependent protease inhibitor binds to the C-terminal domain of protein Z. J. Biol. Chem., 283: 19922-19926.
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  201. Qureshi, S.H., L. Yang, C. Manithody, J.S. Bae and A.R. Rezaie, 2008. Functional properties and active-site topographies of factor X Gla- and prothrombin Gla-domain chimeras of activated protein C. Biochimica Biophysica Acta (BBA)-Gen. Subj., 1780: 1080-1086.
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  202. Qureshi, S.H., C. Manithody, J.S. Bae, L. Yang and A.R. Rezaie, 2008. Autolysis loop restricts the specificity of activated protein C: Analysis by FRET and functional assays. Biophys. Chem., 134: 239-245.
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  203. Monteiro, R.Q., A.R. Rezaie, J.S. Bae, E. Calvo, J.F. Andersen and I. Francischetti, 2008. Ixolaris binding to factor X reveals a precursor state of factor Xa heparin-binding exosite. Protein Sci., 17: 146-153.
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  204. Javed, A., J.S. Bae, F. Afzal, S. Gutierrez and J. Pratap et al., 2008. Structural coupling of Smad and Runx2 for execution of the BMP2 osteogenic signal. J. Biol. Chem., 283: 8412-8422.
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  205. Bae, J.S., L. Yang and A.R. Rezaie, 2008. Lipid raft localization regulates the cleavage specificity of protease activated receptor 1 in endothelial cells. J. Thrombosis Haemostasis, 6: 954-961.
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  206. Bae, J.S. and A.R. Rezaie, 2008. Protease Activated Receptor 1 (PAR-1) activation by thrombin is protective in human pulmonary artery endothelial cells if endothelial protein C receptor is occupied by its natural ligand. Thrombosis Haemostasis, 100: 101-109.
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  207. Yang, L., J.S. Bae, C. Manithody and A.R. Rezaie, 2007. Identification of a specific exosite on activated protein C for interaction with protease-activated receptor 1. J. Biol. Chem., 282: 25493-25500.
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  208. Bae, J.S., S. Gutierrez, R. Narla, J. Pratap and R. Devados et al., 2007. Reconstitution of Runx2/Cbfa1-null cells identifies a requirement for BMP2 signaling through a Runx2 functional domain during osteoblast differentiation. J. Cell. Biochem., 100: 434-449.
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  209. Bae, J.S., L. Yang, C. Manithody and A.R. Rezaie, 2007. The ligand occupancy of endothelial protein C receptor switches the protease-activated receptor 1-dependent signaling specificity of thrombin from a permeability-enhancing to a barrier-protective response in endothelial cells. Blood, 110: 3909-3916.
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  210. Bae, J.S., L. Yang, C. Manithody and A.R. Rezaie, 2007. Engineering a disulfide bond to stabilize the calcium-binding loop of activated protein C eliminates its anticoagulant but not its protective signaling properties. J. Biol. Chem., 282: 9251-9259.
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  211. Bae, J.S., L. Yang and A.R. Rezaie, 2007. Receptors of the protein C activation and activated protein C signaling pathways are colocalized in lipid rafts of endothelial cells. Proc. Natl. Acad. Sci., 104: 2867-2872.
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  212. Lee, B.H., J.S. Bae, R.W. Park, J.E. Kim, J.Y. Park and I.S. Kim, 2006. βig-h3 triggers signaling pathways mediating adhesion and migration of vascular smooth muscle cells through αvβ5 integrin. Exp. Mol. Med., 38: 153-161.
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  213. Park, S.W., J.S. Bae, K.S. Kim, S.H. Park and B.H. Lee et al., 2004. Beta ig-h3 promotes renal proximal tubular epithelial cell adhesion, migration and proliferation through the interaction with α3β1 integrin. Exp. Mol. Med., 36: 211-219.
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  214. Ha, S.W., H.J. Kim, J.S. Bae, G.H. Jeong and S.C. Chung et al., 2004. Elevation of urinary βig-h3, transforming growth factor-β-induced protein in patients with type 2 diabetes and nephropathy. Diabetes Res. Clin. Pract., 65: 167-173.
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  215. Lee, S.H., J.S. Bae, S.H. Park, B.H. Lee and R.W. Park et al., 2003. Expression of TGF-β-induced matrix protein βig-h3 is up-regulated in the diabetic rat kidney and human proximal tubular epithelial cells treated with high glucose. Kidney Int., 64: 1012-1021.
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  216. Ha, S.W., J.S. Bae, H.J. Yeo, S.H. Lee and J.Y. Choi et al., 2003. TGF-β-induced protein βig-h3 is upregulated by high glucose in vascular smooth muscle cells. J. Cell. Biochem., 88: 774-782.
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  217. Ha, S.W., H.J. Yeo, J.S. Bae, S.C. Chung and J.G. Kim et al., 2003. Effect and mechanism of high glucose level on the expression of an adhesion protein, βig-h3 and cellular function in endothelial cells. J. Korean Diabetes Assoc., 27: 323-331.
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  218. Ha, S.W., G.H. Jung, H.J. Yeo, J.S. Bae and S.H. Lee et al., 2002. Effect of transforming growth factor-induced gene product, βig-h3 on proliferation, migration and adhesion of aortic smooth muscle cells cultured in high glucose. J. Korean Diabetes Assoc., 26: 286-295.
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  219. Bae, J.S., S.H. Lee, J.E. Kim, J.Y. Choi and R.W. Park et al., 2002. βig-h3 supports keratinocyte adhesion, migration and proliferation through α3β1 integrin. Biochem. Biophys. Res. Commun., 294: 940-948.
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