Dr. Nazia Binti Abdul Majid
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Dr. Nazia Binti Abdul Majid

Associate Professor
University of Malaya, Malaysia


Highest Degree
Ph.D. in Biomedical Sciences from Newcastle University, UK

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Area of Interest:

Biomedical Sciences
100%
Molecualar Biology
62%
Protein
90%
Cytotaxonomy
75%
Anticancer Activity
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
0
Abstracts
0

Selected Publications

  1. Liu, Y., L. Dong, J. Zheng, M.F.M. Sabri, N. Abdul Majid and S. Ibrahim, 2022. Switchable absorbing, reflecting, and transmitting metasurface by employing vanadium dioxide on the same frequency. Superlattices Microstruct., Vol. 162. 10.1016/j.spmi.2021.107109.
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  2. Fauzi, N.S.A., M.H. Abd Rahim, N. Abdul Majid, R. Othman and J.S. Yaacob, 2022. Evaluation of the effect of jasmonic acid elicitation on composition of pigments and biological activities in green callus of neem (Azadirachta indica). Front. Sustainability Food Syst., Vol. 6. 10.3389/fsufs.2022.1017398.
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  3. Ching, J.J., A.S. Shuib, N. Abdullah, N. Abdul Majid, N.M. Taufek, J. Sutra and M.N.A. Azmai, 2022. Effects of Pleurotus pulmonarius stalk waste extract-supplemented feed on the immune responses of red hybrid tilapia Oreochromis sp. following challenge with pathogen-associated molecular patterns. Aquacult. Res., 53: 5678-5696.
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  4. Samad, M.A., M.Z. Saiman, N. Abdul Majid, S.A. Karsani and J.S. Yaacob, 2021. Berberine inhibits telomerase activity and induces cell cycle arrest and telomere erosion in colorectal cancer cell line, HCT 116. Molecules, Vol. 26. 10.3390/molecules26020376.
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  5. Ching, J.J., A.S. Shuib, N. Abdullah, N. Abdul Majid, N.M. Taufek, J. Sutra and M.N.A. Azmai, 2021. Hot water extract of Pleurotus pulmonarius stalk waste enhances innate immune response and immune-related gene expression in red hybrid tilapia Oreochromis sp. following challenge with pathogen-associated molecular patterns. Fish Shellfish Immunol., 116: 61-73.
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  6. Zain, M.Z.M., N.H. Ismail, N. Ahmad, S. Sulong, S.A. Karsani and N. Abdul Majid, 2020. Telomerase reverse transcriptase downregulation by RNA interference modulates endoplasmic reticulum stress and mitochondrial energy production. Mol. Biol. Rep., 47: 7735-7743.
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  7. Badroon, N., N.A. Majid, F. Al-Suede, M.N.V. and N. Giribabu et al., 2020. Cardamonin exerts antitumor effect on human hepatocellular carcinoma xenografts in athymic nude mice through inhibiting NF-κβ pathway. Biomedicines, Vol. 8. 10.3390/biomedicines8120586.
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  8. Badroon N.A., N.A. Majid and M.A. Alshawsh, 2020. Antiproliferative and apoptotic effects of cardamonin against hepatocellular carcinoma hepg2 cells. Nutrients 12: 1757-1757.
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  9. Yong, W.K., P.E. Lim, V. Vello, K.S. Sim and N.A. Majid et al., 2019. Metabolic and physiological regulation of Chlorella sp. (Trebouxiophyceae, Chlorophyta) under nitrogen deprivation. J. Oceanol. Limnol., 37: 186-198.
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  10. Saremi, K., S.K. Rad, M. Khalilzadeh, J. Hussaini and N. Abdul Majid, 2019. Acute toxicity and anti-gastric evaluation of a novel dichloro Schiff base: Bax and HSP70 alteration. Acta Biochim. Biophys. Sin., 52: 26-37.
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  11. Lai, M.Y., N. Abdul-Majid and Y.L. Lau, 2019. Identification of host proteins interacting with Toxoplasma gondii SAG1 by yeast two-hybrid assay. Acta Parasitol., 64: 575-581.
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  12. Vello, V., W.L. Chu, P.E. Lim, N.A. Majid and S.M. Phang, 2018. Metabolomic profiles of tropical Chlorella species in response to physiological changes during nitrogen deprivation. J. Applied Phycol., 30: 3131-3151.
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  13. Vello, V., S. Umashankar, S.M. Phang, W.L. Chu and P.E. Lim et al., 2018. Metabolomic profiles of tropical Chlorella and Parachlorella species in response to physiological changes during exponential and stationary growth phase. Algal Res., 35: 61-75.
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  14. Nordin, N., N.A. Majid, R. Othman, F.A.A. Omer, M.N.A. Nasharuddin and N.M. Hashim, 2018. Plagioneurin B, a potent isolated compound induces apoptotic signalling pathways and cell cycle arrest in ovarian cancer cells. Apoptosis, 23: 152-169.
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  15. Kadir, M.F.Z., N.S. Salleh, M.H. Hamsan, Z. Aspanut, N.A. Majid and M.F. Shukur, 2018. Biopolymeric electrolyte based on glycerolized methyl cellulose with NH4Br as proton source and potential application in EDLC. Ionics, 24: 1651-1662.
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  16. Hasanpourghadi, M., N.A. Majid and M.R. Mustafa, 2018. The role of miRNAs 34a, 146a, 320a and 542 in the synergistic anticancer effects of methyl 2-(5-fluoro-2-hydroxyphenyl)-1H-benzo[d]imidazole-5-carboxylate (MBIC) with doxorubicin in breast cancer cells. PeerJ, Vol. 6. 10.7717/peerj.5577.
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  17. Hasanpourghadi, M., N.A. Majid and M.R. Mustafa, 2018. Activation of autophagy by stress-activated signals as a cellular self-defense mechanism against the cytotoxic effects of MBIC in human breast cancer cells in vitro. Biochem. Pharmacol., 152: 174-186.
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  18. Omar, H., N. Nordin, P. Hassandarvish, M. Hajrezaie and A.H.S. Azizan et al., 2017. Methanol leaf extract of Actinodaphne sesquipedalis (lauraceae) enhances gastric defense against ethanol-induced ulcer in rats. Drug Des. Dev. Ther., 11: 1353-1365.
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  19. Hajiaghaalipour, F., F.L. Faraj, E. Bagheri, H.M. Ali, M.A. Abdulla and N.A. Majid, 2017. Synthesis and characterization of a new benzoindole derivative with apoptotic activity against colon cancer cells. Curr. Pharmaceut. Des., 23: 6358-6365.
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  20. Hajiaghaalipour, F., E. Bagheri, F.L. Faraj, M.A. Abdulla and N.A. Majid, 2017. Underlying mechanism for the modulation of apoptosis induced by a new benzoindole derivative on HT-29 colon cancer cells. RSC Adv., 7: 38257-38263.
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  21. Nordin, N., N.A. Majid, S. Mohan, F. Dehghan and H. Karimian et al., 2016. Cleistopholine isolated from Enicosanthellum pulchrum exhibits apoptogenic properties in human ovarian cancer cells. Phytomedicine, 23: 406-416.
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  22. Nordin, N., M. Fadaeinasab, S. Mohan, N.M. Hashim and R. Othman et al., 2016. Pulchrin A, a new natural coumarin derivative of Enicosanthellum pulchrum, induces apoptosis in ovarian cancer cells via intrinsic pathway. PLoS ONE, Vol. 11. 10.1371/journal.pone.0154023.
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  23. Chen, J.T., E.M. Mustafa, V. Vello, P. Lim and N.N. Sulaiman et al., 2016. Preliminary assessment of Malaysian micro-algae strains for the production of bio jet fuel. IOP Conf. Ser.: Mater. Sci. Eng., Vol. 152, No. 1. 10.1088/1757-899X/152/1/012042.
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  24. Zahedifard, M., F.L. Faraj, M. Paydar, C.Y. Looi and P. Hasandarvish et al., 2015. Synthesis of apoptotic new quinazolinone-based compound and identification of its underlying mitochondrial signalling pathway in breast cancer cells. Curr. Pharmaceut. Des., 21: 3417-3426.
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  25. Zahedifard, M., F.L. Faraj, M. Paydar, C.Y. Looi and M. Hajrezaei et al., 2015. Synthesis, characterization and apoptotic activity of quinazolinone Schiff base derivatives toward MCF-7 cells via intrinsic and extrinsic apoptosis pathways. Scient. Rep., Vol. 5. 10.1038/srep11544.
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  26. Phang, S.M., E.M. Mustafa, R.R. Ambati, N.M.N. Sulaiman and P.E. Lim et al., 2015. Checklist of microalgae collected from different habitats in Peninsular Malaysia for selection of algal biofuel feedstocks. Malaysian J. Sci., 34: 148-172.
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  27. Nordin, N., N.A. Majid, N.M. Hashim, M.A. Rahman, Z. Hassan and H.M. Ali, 2015. Liriodenine, an aporphine alkaloid from Enicosanthellum pulchrum, inhibits proliferation of human ovarian cancer cells through induction of apoptosis via the mitochondrial signaling pathway and blocking cell cycle progression. Drug Des. Dev. Ther., 9: 1437-1448.
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  28. Hajrezaie, M., N. Salehen, H. Karimian, M. Zahedifard and K. Shams et al., 2015. Biochanin a gastroprotective effects in ethanol-induced gastric mucosal ulceration in rats. PLoS ONE, Vol. 10. 10.1371/journal.pone.0121529.
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  29. Hajrezaie, M., M. Paydar, C.Y. Looi, S.Z. Moghadamtousi and P. Hassandarvish et al., 2015. Apoptotic effect of novel Schiff Based CdCl2(C14H21N3O2) complex is mediated via activation of the mitochondrial pathway in colon cancer cells. Scient. Rep., Vol. 5. 10.1038/srep09097.
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  30. Hajrezaie, M., K. Shams, S.Z. Moghadamtousi, H. Karimian and P. Hassandarvish et al., 2015. Chemoprevention of colonic aberrant crypt foci by novel schiff based dichlorido(4-methoxy-2-{[2-(piperazin-4-ium-1-Yl)ethyl]iminomethyl}phenolate)Cd complex in azoxymethane-induced colorectal cancer in rats. Scient. Rep., Vol. 5. 10.1038/srep12379.
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  31. Daim, L.D.J., T.E.K. Ooi, N. Ithnin, H.M. Yusof, H. Kulaveerasingam, N.A. Majid and S.A. Karsani, 2015. Comparative proteomic analysis of oil palm leaves infected with Ganoderma boninense revealed changes in proteins involved in photosynthesis, carbohydrate metabolism and immunity and defense. Electrophoresis, 36: 1699-1710.
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  32. Daim, L.D.J., T.E.K. Ooi, H.M. Yusof, N.A. Majid and S.A.B. Karsani, 2015. Optimization of protein extraction and two-dimensional electrophoresis protocols for oil palm leaf. Protein J., 34: 304-312.
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  33. Ata, N., N.A. Yusuf, B.C. Tan, A. Husaini, Y.M. Yusuf, N.A. Majid and N. Khalid, 2015. Expression profiles of flavonoid-related gene, 4 coumarate: Coenzyme A ligase and optimization of culturing conditions for the selected flavonoid production in Boesenbergia rotunda. Plant Cell Tissue Org. Cult., 123: 47-55.
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  34. Yusof, Y.M., N.A. Majid, R.M. Kasmani, H.A. Illias and M.F.Z. Kadir, 2014. The effect of plasticization on conductivity and other properties of starch/chitosan blend biopolymer electrolyte incorporated with ammonium iodide. Mol. Cryst. Liquid Cryst., 603: 73-88.
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  35. Vello, V., S.M. Phang, W.L. Chu, N.A. Majid, P.E. Lim and S.K. Loh, 2014. Lipid productivity and fatty acid composition-guided selection of Chlorella strains isolated from Malaysia for biodiesel production. J. Applied Phycol., 26: 1399-1413.
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  36. Nursu'aidah, H., M.R. Motior, A.M. Nazia and M.A. Islam, 2014. Growth and photosynthetic responses of long bean (Vigna unguiculata) and mung bean (Vigna radiata) response to fertilization. J. Anim. Plant Sci., 24: 573-578.
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  37. Nordin, N., S.M. Salama, S. Golbabapour, M. Hajrezaie and P. Hassandarvish et al., 2014. Anti-ulcerogenic effect of methanolic extracts from Enicosanthellum pulchrum (King) Heusden against ethanol-induced acute gastric lesion in animal models. PloS One, Vol. 9. 10.1371/journal.pone.0111925.
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  38. Hajrezaie, M., P. Hassandarvish, S.Z. Moghadamtousi, N.S. Gwaram and S. Golbabapour et al., 2014. Chemopreventive evaluation of a Schiff base derived copper (II) complex against azoxymethane-induced colorectal cancer in rats. PLoS ONE, Vol. 9. 10.1371/journal.pone.0091246.
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  39. Hajrezaie, M., M. Paydar, S.Z. Moghadamtousi, P. Hassandarvish and N.S. Gwaram et al., 2014. A Schiff Base-derived copper (II) complex is a potent inducer of apoptosis in colon cancer cells by activating the intrinsic pathway. Scient. World J., Vol. 2014. 10.1155/2014/540463.
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  40. Faraj, F.L., M. Zahedifard, M. Paydar, C.Y. Looi and N.A. Majid et al., 2014. Synthesis, characterization and anticancer activity of new quinazoline derivatives against MCF-7 cells. Scient. World J., Vol. 2014. 10.1155/2014/212096.
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  41. Shukur, M.F., N.A. Majid, R. Ithnin and M.F.Z. Kadir, 2013. Effect of plasticization on the conductivity and dielectric properties of starch-chitosan blend biopolymer electrolytes infused with NH4Br. Physica Scripta, Vol. 2013. 10.1088/0031-8949/2013/T157/014051.
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  42. Shukur, M.F., M.S. Azmi, S.M.M. Zawawi, N.A. Majid, H.A. Illias and M.F.Z. Kadir, 2013. Conductivity studies of biopolymer electrolytes based on chitosan incorporated with NH4Br. Physica Scripta, Vol. 2013. 10.1088/0031-8949/2013/T157/014049.
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  43. Shukur, M.F., F.M. Ibrahim, N.A. Majid, R. Ithnin and M.F.Z. Kadir, 2013. Electrical analysis of amorphous corn starch-based polymer electrolyte membranes doped with LiI. Physica Scripta, Vol. 88, No. 2. 10.1088/0031-8949/88/02/025601.
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  44. Ketuly, K.A., A.H.A. Hadi, S. Golbabapour, M. Hajrezaie and P. Hassandarvish et al., 2013. Acute toxicity and gastroprotection studies with a newly synthesized steroid. PLoS ONE, Vol. 8. 10.1371/journal.pone.0059296.
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  45. Golbabapour, S., N.S. Gwaram, P. Hassandarvish, M. Hajrezaie and B. Kamalidehghan et al., 2013. Gastroprotection studies of Schiff base zinc (II) derivative complex against acute superficial hemorrhagic mucosal lesions in rats. PLoS ONE, Vol. 8. 10.1371/journal.pone.0075036.
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  46. Golbabapour, S., N.S. Gwaram, M.M.J. Al-Obaidi, A.F. Soleimani, H.M. Ali and N.A. Majid, 2013. Schiff base metal derivatives enhance the expression of HSP70 and suppress BAX proteins in prevention of acute gastric lesion. BioMed Res. Int., Vol. 2013. 10.1155/2013/703626.
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  47. Golbabapour, S., N.A. Majid, P. Hassandarvish, M. Hajrezaie, M.A. Abdulla and A.H.A. Hadi, 2013. Gene silencing and Polycomb group proteins: An overview of their structure, mechanisms and phylogenetics. Omics: J. Integr. Biol., 17: 283-296.
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  48. Golbabapour, S., M. Hajrezaie, P. Hassandarvish, N.A. Majid, A.H. Hadi and N. Nordin, 2013. Acute toxicity and gastroprotective role of M. pruriens in ethanol-induced gastric mucosal injuries in rats. Biomed. Res. Int. 10.1155/2013/974185.
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  49. Al-Abd, N.M., M.A.K. Mahdy, A.M.Q. Al-Mekhlafi, G. Snounou, N.B. Abdul-Majid, H.M. Al-Mekhlafi and M.Y. Fong, 2013. The suitability of P. falciparum merozoite surface proteins 1 and 2 as genetic markers for in vivo drug trials in Yemen. PLoS ONE, Vol. 8. 10.1371/journal.pone.0067853.
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  50. Ismail, I.F., S. Golbabapour, P. Hassandarvish, M. Hajrezaie and N.A. Majid et al., 2012. Gastroprotective activity of Polygonum chinense aqueous leaf extract on ethanol-induced hemorrhagic mucosal lesions in rats. Evid. Based Complementary Altern. Med., Vol. 2012. 10.1155/2012/404012.
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  51. Ibrahim, I.A.A., M.A. Abdulla, S.I. Abdelwahab, F. Al-Bayaty and N.A. Majid, 2012. Leaves extract of Muntingia calabura protects against gastric ulcer induced by ethanol in Sprague-dawley rats. Clin. Exp. Pharmacol., Vol. S5. 10.4172/2161-1459.S5-004.
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  52. Hussaini, J., N.A. Othman, M.A. Abdulla, N.A. Majid, H.M. Faroq and S. Ismail, 2012. Gastroprotective effects of Dicranopteris linearis leaf extract against ethanol-induced gastric mucosal injury in rats. Scient. Res. Essays, 7: 1761-1767.
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  53. Hajrezaie, M., S. Golbabapour, P. Hassandarvish, N.S. Gwaram and A.H.A. Hadi et al., 2012. Acute toxicity and gastroprotection studies of a new Schiff base derived copper (II) complex against ethanol-induced acute gastric lesions in rats. PLoS ONE, Vol. 7. 10.1371/journal.pone.0051537.
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  54. Osman, M., F. Golam, S. Saberi, N.A. Majid, N.H. Nagoor and M. Zulqarnain, 2011. Morpho-agronomic analysis of three roselle (Hibiscus sabdariffa L.) mutants in tropical Malaysia. Aust. J. Crop Sci., 5: 1150-1156.
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  55. Golam, F., Y.H. Yin, A. Masitah, N. Afnierna, N.A. Majid, N. Khalid and M. Osman, 2011. Analysis of aroma and yield components of aromatic rice in Malaysian tropical environment. Aust. J. Crop Sci., 5: 1318-1325.
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  56. Golam, F., N. Farhana, M.F. Zain, N.A. Majid, M.M. Rahman, M.M. Rahman and M. Abdul Kadir, 2011. Grain yield and associated traits of maize (Zea mays L.) genotypes in Malaysian tropical environment. Afr. J. Agric. Res., 6: 6147-6154.
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  57. Golam, F., K. NorZulaani, A.H. Jennifer, B. Subha and M. Zulqarnain et al., 2010. Evaluation of kernel elongation ratio and aroma association in global popular aromatic rice cultivars in tropical environment. Afr. J. Agric. Res., 5: 1515-1522.
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  58. Seitan, V.C., P. Banks, S. Laval, N.A. Majid and D. Dorsett et al., 2006. Metazoan Scc4 homologs link sister chromatid cohesion to cell and axon migration guidance. PLoS Biol., Vol. 4. 10.1371/journal.pbio.0040242.
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