Dr. David Izuchukwu Ugwu
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Dr. David Izuchukwu Ugwu

Lecturer
University of Nigeria Nsukka, Nigeria

Highest Degree
Ph.D. in Organic Chemistry from University of Nigeria, Nsukka, Nigeria

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Area of Interest:

Chemistry
100%
Industrial Chemistry
62%
Organic Chemistry
90%
Molecular Modelling
75%
Synthesis
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
0
Abstracts
0

Selected Publications

  1. Ugwuja, D.I., U.C. Okoro, S.S. Soman, R. Soni, S.N. Okafor and D.I. Ugwu, 2019. New peptide derived antimalaria and antimicrobial agents bearing sulphonamide moiety. J. Enzyme Inhibition Med. Chem., 34: 1388-1399.
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  2. Ugwu, D.I., F.U. Eze, B.C. Ogboo, V.N. Okoro and M.C. Ugwu, 2019. Synthesis of multi-target benzene-sulphonamide derivatives for the treatment of trypanosomiasis. Med. Chem., 9: 83-92.
  3. Ugwu, D.I., E.F. Uchenna, U.C. Okoro and S.N. Okafor, 2019. Biological activity evaluation of some new benzenesulphonamide derivatives. Fron. Chem., Vol. 7. 10.3389/fchem.2019.00634.
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  4. Ogboo, B.C., S.N. Okafor, D.I. Ugwu, S.E. Shaibu, N. Efiong and V.F. Ekpo, 2019. Oxazine and its derivatives: Potential leads for discovery of new and potent antimicrobial and antituberculosis drugs, a review. Global Scient. J., 7: 181 -202.
  5. Ezeokonkwo, M.A., K.C. Iloka, U.C. Okoro, E.A. Onoabedje, B.E. Ezema, F.N. Ibeanu, D.I. Ugwu, Eze, F.U. and C.P. Uzoewulu, 2019. Synthesis and antimicrobial activity of new derivatives of angular polycyclic phenoxazine ring system. Oriental J. Chem., 35: 1320-1326.
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  6. Eze, F.U., U.C. Okoro, D.I. Ugwu and S.N. Okafor, 2019. New carboxamides bearing benzenesulphonamides: Synthesis, molecular docking and pharmacological properties. Bioorg. Chem., Vol. 92. 10.1016/j.bioorg.2019.103265.
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  7. Ugwuja, D.I., U.C. Okoro and D.I. Ugwu, 2018. Synthesis, antibacterial, antifungal and antioxidant activities of N-pyridin-3-yl-substituted [phenylsulphonamido]acetamide derivatives. Pak. J. Pharm. Sci., 31: 1209-1216.
  8. Ugwu, D.I., U.C. Okoro, P.O. Ukoha, S. Okafor and A. Gupta, 2018. Novel anti-inflammatory and analgesic agents: Synthesis, molecular docking and in vivo studies. J. Enzyme Inhib. Med. Chem., 33: 405 -415.
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  9. Ugwu, D.I., U.C. Okoro, N.K. Mishra and S.N. Okafor, 2018. Novel phenoxazinones as potent agonist of PPAR-α: Design, synthesis, molecular docking and in vivo studies. Lipids Health Dis.,Vol. 120. 10.1186/s12944-018-0764-y.
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  10. Ugwu, D.I., U.C. Okoro and N.K. Mishra, 2018. Synthesis, characterization and anthelmintic activity evaluation of pyrimidine derivatives bearing carboxamide and sulphonamide moieties. J. Serb. Chem. Soc., 83: 401-409.
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  11. Ugwu, D.I., U.C. Okoro and N.K. Mishra, 2018. Synthesis, characterization and in Vitro antitrypanosomal activities of new carboxamides bearing quinoline moiety. PLOS ONE, Vol. 13. 10.1371/journal.pone.0191234.
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  12. Ugwu, D.I., U.C. Okoro and N.K. Mishra, 2018. Synthesis of proline derived benzenesulfonamides: A potent anti-Trypanosoma brucei gambiense agent. Eur. J. Med. Chem., 154: 110-116.
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  13. Ezema, B.E., S.N. Okafor, S.A. Agada, D.I. Ugwu and C.G. Ezema, 2018. Synthesis, in silico and in vitro studies of potential glucosamine‐6‐phosphate synthase and lanosterol‐14α‐demethylase inhibitors. Chem. Select, 3 : 12001-12006.
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  14. Ezema, B., C. Ezema, K. Akpomie and D. Ugwu, 2018. Synthetic process of vat-dyes of tetraaza derivatives of three-branched phenothiazine heterocycles. Leonardo Electr. J. Pract. Technol., 17: 277-288.
  15. Ugwu, D.I., U.C. Okoro, P.O. Ukoha, S. Okafor, A. Ibezim and N.M. Kumar, 2017. Synthesis, characterization, molecular docking and in vitro antimalarial properties of new carboxamides bearing sulphonamide. Eur. J. Med. Chem., 135: 349-369.
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  16. Ugwu, D.I., U.C. Okoro and H. Ahmad, 2017. New carboxamide derivatives bearing benzenesulphonamide as a selective COX-II inhibitor: Design, synthesis and structure-activity relationship. PLOS ONE, Vol. 12. 10.1371/journal.pone.0183807.
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  17. Ugwu, D.I., B.E. Ezema, U.C. Okoro, F.U. Eze, O.C. Ekoh, M.C. Egbujor and D.I. Ugwuja, 2015. Syntheses and pharmacological applications of chalcones: A review. Int. J. Chem. Sci., 13: 459-500.
  18. Ugwu, D.I., B.E. Ezema, F.U. Eze, E.A. Onoabedje, C.G. Ezema, O.C. Ekoh and J.I. Ayogu, 2015. Synthesis and antimalarial activities of chalcone derivatives, Int. J. Chem. Tech. Res., 7: 1966-1984.
  19. Oni, T.T., U.C. Okoro and D.I. Ugwu, 2015. Synthesis of 1-azabenzo[a]phenoxazin-5-one and 11-amino-1,8,10-triazabenzo[a]phenoxazin-5-one and their functionalized aryl derivatives via mizoroki-heck arylation methodology. Oriental J. Chem., 31: 371-378.
  20. Odaa, M.E., U.C. Okoro and D.I. Ugwu, 2015. Synthesis of Novel Angular Diazaphenoxazinone Derivatives via palladium catalyzed buchwald-hartwig amidation protocols. Asian J. Chem., 27: 3069-3073.
  21. Ezema, B.E., C.G. Ezema, J.I. Ayogu, D.I. Ugwu and E.A. Onoabedje, 2015. Synthesis of tetraaza derivatives of benzoxazinophenothiazine. Oriental J. Chem., 31: 133-139.
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  22. Ezema, B.E., C.G. Ezema, J.I. Ayogu, D.I. Ugwu and E.A. Onoabedje, 2015. Synthesis of aza derivatives of isomers of angular and complex phenothiazine rings. Oriental J. Chem., 31: 379-385.
  23. Egbujor, M.C., U.C. Okoro and D.I. Ugwu, 2015. Synthesis of new derivatives of 1-azaphenothiazine via buchwald-hartwig amination methodology. Asian J. Chem., 27: 1469-1472.
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  24. Edoka, O.L., U.C. Okoro and D.I. Ugwu, 2015. Synthesis of 1,9-diazaphenoxazine carboxamide derivatives via buchwald-hartwig amidation protocol. Asian J. Chem., 27: 3463-3467.
  25. Ugwu, D.I., U.C. Okoro and T.D. Chukwurah, 2014. Nickel catalyzed synthesis of N-aryl and N-heteroaryl substituted benzene sulphonamides and their biological activity evaluation. Med. Chem., 4: 357-360.
  26. Ugwu, D.I. and U.C. Okoro, 2014. Synthesis, characterisation and antifungal activities of [4- methylphenyl sulphonamide]-N-(pyridin-2-yl)acetamide derivatives, Med. Chem., 4: 330-333.
  27. Ugwu D.I. and U.C. Okoro, 2014. Synthesis, characterisation and evaluation for antibacterial activities of n-pyridin-2-yl substituted-p-toluene sulphonamoyl ethanamides. Int. J. Sci. Res., 3: 35-38.
    Direct Link  |  
  28. Francisca, C.O., Chris, O.U. and U.D. Izuchukwu, 2014. Synthesis and antimicrobial activities of N-(Heteroaryl-substituted)-p-toluenesulphonamides. Organic Chem. Int. 2014. 10.1155/2014/748257.
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  29. Ezema, B.E, C.G. Ezema, D.I. Ugwu and J.I. Ayogu, 2014. Synthesis of heterocyclic azo dyes from quinolin-8-ol Chem. Materials Res., 6: 1-6.
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  30. Adekola, E.O., B.E. Ezema, J.I. Ayogu, , D.I. Ugwu C.G. Ezema, P.N. Abuekwu and C.O. Ike, 2014. Synthesis of benzothiazinophenothiazine derivatives and their antimicrobial screening. Orient. J. Chem., 30: 1493-1500.
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  31. Ugwu, D.I., B.E. Ezema, F.U. Eze and D.I. Ugwuja, 2014. Synthesis and structural activity relationship study of antitubercular carboxamides. Int. J. Med. Chem., 2014. 10.1155/2014/614808.
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  32. Onoabedje, E.A., B.E. Ezema, C.G. Ezema and D.I. Ugwu, 2013. Synthesis of some derivatives of benzophenothiazinone of pharmaceutical interests via nickel catalysed grignard couplings. Chem. Process Eng. Res., 8: 6-11.
  33. Ezema, B.E., C.G. Ezema, E.A. Onoabedje and D.I. Ugwu, 2013. Synthesis of a new and firsttriazadibenzo [A,N] triphenodithiazine. Chem. Process Eng. Res., 8: 35-41.