Dr. Hany Ahmed Mostafa M. Omar
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Dr. Hany Ahmed Mostafa M. Omar

Assistant Professor
Beni-Suef University, Egypt

Highest Degree
PostDoc Fellow in Cancer Research from The Ohio State University, USA

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Biography

Dr. Hany A. Omar is currently working as Assistant Professor of Pharmacology and Molecular Therapeutics, College of Clinical Pharmacy, Taif University (TU), KSA. He obtained his PhD in Molecular Pharmacology from The Ohio State University, USA. He also worked as Clinical Pharmacist at the National Cancer Institute, Assistant lecturer, Lecturer and Graduate Research Associate and Instructor of Pharmacology & Toxicology at Cairo University, Beni-Suef Campus, Egypt, Graduate Research Associate, Teaching Assistant, and Post-Doctoral Fellow at The Ohio State University (OSU), Columbus, OH, USA. He has published 15 articles in journals and 12 scientific abstract and poster presentations. Dr. Hany A Omar received number of honors includes, The winner of 107,000 SR grant for a research proposal from Taif University Vice-Presidency for Graduate Studies and Research, The winner of 31,000 LE Scientific Publications Awards for the best published research article, The National Institutes of Health (NIH) travel award, American Association of Cancer Research (AACR) award, and Invited Member of the National Honor Society of Phi Kappa Phi. His area of professional interest includes Molecular Mechanisms of Anticancer Drugs, Molecular Pharmacology as a basis for Drugs Development, Molecular Pharmacology as a basis for Cardiovascular Drugs Development, Oxidative Stress and Antioxidants Implication in the Path Physiology of many Clinical Disorders. He is professional member of different societies such as European Association for Cancer Research (EACR), American Association for Cancer Research (AACR), The Egyptian Society of Pharmacology and Experimental Therapeutics, The American Association of Pharmaceutical Scientists, The Honor Society of Phi Kappa Phi, American Society Clinical Pharmacology Therapeutics, American Society for Biochemistry and Molecular Biology, The General Syndicate of Pharmacists in Egypt, and The Egyptian Association of Pharmacists. He is also serving as invited reviewer in many journals, and Associate Editor for Beni-Suef University Journal of Applied Sciences. He is also working as member of the board of trustees of Egyptian Student Association in North America (ESANA).

Area of Interest:

Pharmacology and Toxicology
100%
Molecular Pharamcology
62%
Cancer Research
90%
Drug Discovery
75%
Tumor Pharmacology
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
0
Abstracts
0

Selected Publications

  1. Wu, J.J., H.A. Omar, Y.R. Lee, Y.N. Teng and P.S. Chen et al., 2015. 6-Shogaol induces cell cycle arrest and apoptosis in human hepatoma cells through pleiotropic mechanisms. Eur. J. Pharmacol., 762: 449-458.
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  2. Salama, S.A., M.S. Al-Harbi, M.S. Abdel-Bakky and H.A. Omar, 2015. Glutamyl cysteine dipeptide suppresses ferritin expression and alleviates liver injury in iron-overload rat model. Biochimie, 115: 203-211.
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  3. Omar, H.A., W.R. Mohamed, E.S.A. Arafa, B.A. Shehata, G.A.E. Sherbiny, H.H. Arab and A.N.A.M. Elgendy, 2015. Hesperidin alleviates cisplatin-induced hepatotoxicity in rats without inhibiting its antitumor activity. Pharmacol. Rep., 10.1016/j.pharep.2015.09.007.
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  4. Mizar, S.M., H.A. Omar, G.A. El Sherbiny and M.A. El-moselhy, 2015. Nebivolol and chrysin protect the liver against ischemia/reperfusion-induced injury in rats. Beni-Suef Univ. J. Basic Appl. Sci., 4: 86-92.
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  5. Hung, J.H., C.Y. Chen, H.A. Omar, K.Y. Huang and C.C. Tsao et al., 2015. Reactive oxygen species mediate Terbufos-induced apoptosis in mouse testicular cell lines via the modulation of cell cycle and pro-apoptotic proteins. Environ. Toxicol., 10.1002/tox.22190.
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  6. Azouz, A.A., H.A. Omar, A.M. Abo-yousef, G.A. El-Sherbiny and H.A. Abdel-latif, 2015. Trimetazidine, sildenafil and coenzyme Q10 protect rats' kidney from ischemia/reperfusion injury. Br. J. Pharmacol. Toxicol., 6: 64-69.
  7. Arab, H.H., S.A. Salama, H.A. Omar, E.S.A. Arafa and I.A. Maghrabi, 2015. Diosmin protects against ethanol-induced gastric injury in rats: Novel anti-ulcer actions. Plos One, Vol. 10. 10.1371/journal.pone.0122417.
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  8. Abdellatif, K.R., P.F. Lamie and H.A. Omar, 2015. 3-Methyl-2-phenyl-1-substituted-indole derivatives as indomethacin analogs: Design, synthesis and biological evaluation as potential anti-inflammatory and analgesic agents. J. Enzyme Inhib. Med. Chem., 10.3109/14756366.2015.1022174.
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  9. Abdellatif, K.R., E.K. Abdelall, M.A. Abdelgawad, M.M. Abdelhakeem and H.A. Omar, 2015. Design and synthesis of certain novel arylidene thiazolidinone derivatives as anticancer agents. Der Pharma Chem., 7: 149-161.
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  10. AbdEllraheim, M.A., A.M. AboYoussef, H.A. Omar and H.A. AbdEllatif, 2015. Angiotensin inhibitors potentiate the hypoglycemic and antioxidant effects of gliclazide in rats. Int. J. Pharm. Sci. Rev. Res., 31: 75-80.
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  11. Salama, S.A., H.H. Arab, H.A. Omar, I.A. Maghrabi and R.M. Snapka, 2014. Nicotine mediates hypochlorous acid-induced nuclear protein damage in mammalian cells. Inflammation, 37: 785-792.
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  12. Salama, S.A., H.A. Omar, I.A. Maghrabi, M.S. AlSaeed and A.E. EL-Tarras, 2014. Iron supplementation at high altitudes induces inflammation and oxidative injury to lung tissues in rats. Toxicol. Appl. Pharmacol., 274: 1-6.
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  13. Omar, H.A., M.F. Tolba and M.M. Saber-Ayad, 2014. Potential targets of energy restriction mimetic agents in cancer cells. Future Oncol., 10: 2547-2550.
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  14. Omar, H.A., E.S.A. Arafa, I.A. Maghrabi and J.R. Weng, 2014. Sensitization of hepatocellular carcinoma cells to Apo2L/TRAIL by a Novel Akt/NF-κB signalling inhibitor. Basic Clin. Pharmacol. Toxicol., 114: 464-471.
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  15. Lee, K.H., W.Y. Ho, S.J. Wu, H.A. Omar and P.J. Huang et al., 2014. Modulation of cyclins, p53 and Mitogen-Activated Protein Kinases signaling in breast cancer cell lines by 4-(3,4,5-Trimethoxyphenoxy)benzoic acid. Int. J. Mol. Sci., 15: 743-757.
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  16. Elhemely, M.A., H.A. Omar, A.A. Ain-Shoka, H.A. Abd El-Latif, A.M. Abo-Youssef and G.A. El Sherbiny, 2014. Rosuvastatin and ellagic acid protect against isoproterenol-induced myocardial infarction in hyperlipidemic rats. Beni-Suef Univ. J. Basic Applied Sci., 3: 239-246.
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  17. El-Nezhawy, A.O.H., I.A. Maghrabi, K.M. Mohamed and H.A. Omar, 2014. Cymbopogon proximus extract decreases L-NAME-induced hypertension in rats. Int. J. Pharm. Sci. Rev. Res., 27: 66-69.
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  18. Arafa, E.A., A.H. Abdelazeem, H.H. Arab and H.A. Omar, 2014. OSU-CG5, a novel energy restriction mimetic agent, targets human colorectal cancer cells in vitro. Acta Pharmacol. Sin., 35: 394-400.
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  19. Arab, H.H., S.A. Salama, A.H. Eid, H.A. Omar and E.S.A. Arafa et al., 2014. Camel's milk ameliorates TNBS-induced colitis in rats via downregulation of inflammatory cytokines and oxidative stress. Food Chem. Toxicol., 69: 294-302.
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  20. Abdellatif, K.R., H.A. Elshemy, S.A. Salama and H.A. Omar, 2014. Synthesis, characterization and biological evaluation of novel 4'-fluoro-2'-hydroxy-chalcone derivatives as antioxidant, anti-inflammatory and analgesic agents. J. Enzyme Inhib. Med. Chem., 30: 484-491.
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  21. Abdelazeem, A.H., S.A. Abdelatef, M.T. El-Saadi, H.A. Omar and S.I. Khan et al., 2014. Novel pyrazolopyrimidine derivatives targeting COXs and iNOS enzymes; design, synthesis and biological evaluation as potential anti-inflammatory agents. Eur. J. Pharm. Sci., 62: 197-211.
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  22. Abdelazeem, A.H., A.M. Gouda, H.A. Omar and M.F. Tolba, 2014. Design, synthesis and biological evaluation of novel diphenylthiazole-based cyclooxygenase inhibitors as potential anticancer agents. Bioorg. Chem., 57: 132-141.
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  23. Tolba, M.F., H.A. Omar, S.S. Azab, A.E. Khalifa, A.B. Abdel-Naim and S.Z. Abdel-Rahman, 2013. Caffeic acid phenethyl ester: A review of its antioxidant, antimicrobial activities, protective effects against ischemia reperfusion injury and drug adverse reactions. Crit. Rev. Food Sci. Nutr. 10.1080/10408398.2013.821967.
    CrossRef  |  PubMed  |  
  24. Omar, H.A., S.A. Salama, E.S.A. Arafa and J.R. Weng, 2013. Antitumor effects of energy restriction-mimetic agents: Thiazolidinediones. Biol. Chem., 394: 865-870.
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  25. Omar, H.A., S.A. Arafa, S.A. Salama and J.R. Weng, 2013. OSU-A9 inhibits angiogenesis in human umbilical vein endothelial cells via disrupting Akt-NF-κB and MAPK signaling pathways. Toxicol. Applied Pharmacol., 272: 616-624.
  26. Omar, H.A., E.S.A. Arafa, S.A. Salama, H.H. Arab and C.H. Wu et al., 2013. OSU-A9 inhibits angiogenesis in human umbilical vein endothelial cells via disrupting Akt-NF-κB and MAPK signaling pathways. Toxicol. Appl. Pharmacol., 272: 616-624.
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  27. El-Nezhawy, A.O.H., A.R. Biuomy, F.S. Hassan, A.K. Ismaiel and H.A. Omar, 2013. Design, synthesis and pharmacological evaluation of omeprazole-like agents with anti-inflammatory activity. Bioorg. Med. Chem., 21: 1661-1670.
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  28. Abdellatif, K.R.A., A. Belal and H.A. Omar, 2013. Design, synthesis and biological evaluation of novel triaryl (Z)-olefins as tamoxifen analogues. Bioorg. Med. Chem. Lett., 23: 4960-4963.
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  29. Abdelgawad, M.A., H.A.H. Elshemy, K.R.A. Abdellatif and H.A. Omar, 2013. Synthesis of novel substituted 4H-chromenes and their antioxidant screening. J. Chem. Pharm. Res., 5: 387-394.
    Direct Link  |  
  30. Abdelgawad, M.A., A. Belal, H.A. Omar, L. Hegazy and M.E. Rateb, 2013. Synthesis, anti-breast cancer activity, and molecular modeling of some benzothiazole and benzoxazole derivatives. Arch. Pharm., 346: 534-541.
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  31. Omar, H.A., L. Berman-Booty and J.R. Weng, 2012. Energy restriction: Stepping stones towards cancer therapy. Future Oncol., 8: 1503-1506.
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  32. Omar, H.A., E.S.A. Arafa and J.R. Weng, 2012. Abstract B48: Sensitization of hepatocellular carcinoma cells to trail by a novel Aκt/NF-kappaB signaling inhibitor. Clin. Cancer Res., Vol. 18. 10.1158/1078-0432.MECHRES-B48.
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  33. Omar, H.A., C.C. Chou, L.D. Berman-Booty, Y. Ma and J.H. Hung et al., 2011. Antitumor effects of OSU-2S, a nonimmunosuppressive analogue of FTY720, in hepatocellular carcinoma. Hepatology, 53: 1943-1958.
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  34. Bai, L.Y., H.A. Omar, C.F. Chiu, Z.P. Chi, J.L. Hu and J.R. Weng, 2011. Antitumor effects of (S)-HDAC42, a phenylbutyrate-derived histone deacetylase inhibitor, in multiple myeloma cells. Cancer Chemother. Pharmacol., 68: 489-496.
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  35. Weng, J.R., L.Y. Bai, H.A. Omar, A.M. Sargeant and C.T. Yeh et al., 2010. A novel indole-3-carbinol derivative inhibits the growth of human oral squamous cell carcinoma in vitro. Oral Oncol., 46: 748-754.
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  36. Weng, J.R., H.A. Omar, S.K. Kulp and C.S. Chen, 2010. Pharmacological exploitation of indole-3-carbinol to develop potent antitumor agents. Mini-Rev. Med. Chem., 10: 398-404.
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  37. Omar, H.A., L. Berman-Booty, S.K. Kulp and C.S. Chen, 2010. Energy restriction as an antitumor target. Future Oncol., 6: 1675-1679.
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  38. Weng, J.R., C.H. Tsai, H.A. Omar, A.M. Sargeant and D. Wang et al., 2009. OSU-A9, a potent indole-3-carbinol derivative, suppresses breast tumor growth by targeting the Akt-NF-κB pathway and stress response signaling. Carcinogenesis, 30: 1702-1709.
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  39. Omar, H.A., A.M. Sargeant, J.R. Weng, D. Wang and S.K. Kulp et al., 2009. Targeting of the Akt-nuclear factor-κB signaling network by [1-(4-chloro-3-nitrobenzenesulfonyl)-1H-indol-3-yl]-methanol (OSU-A9), a novel indole-3-carbinol derivative, in a mouse model of hepatocellular carcinoma. Mol. Pharmacol., 76: 957-968.
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