About
Professional Summary
Dr. Ali M. Ardekani is currently working as Associate Professor at National Institute of Genetic Engineering and Biotechnology Shahrake Pajoohesh, Tehran-Iran, and Director at Middle-Eastern Association for Cancer Research, Canada, and Health Biotechnology Convention Pasteur Institute of Iran. He obtained his Ph.D. in Endocrinology from Shahid Beheshti University, Iran. Dr. Ali M. Ardekani received honors includes Recipient of a 42,000.00 Grant from the International Center for Genetic Engineering and Biotechnology (ICGEB) from the country of Iran, Cancer Research Award, National Cancer Institute, USA, NIH Postdoctoral Training Grant, Northwestern University, IL, and AACR-AFLAC Scholar in Cancer Research Award. He is member of Iran National Cancer steering Committee and a founding member of the Iranian society for Health Genomics and Biotechnology, Eastern Association for Cancer Research (MEACR), National Cancer Research and Education Committee, Iran cancer Society, One of the Founders and member of the board of Directors in Health Biotechnology Society (Iran). He is Founder and first Editor-in-Chief of Avicenna Journal of Medical Biotechnology, and member of editorial board in journals. He has published 8 books, 1 book chapter, 1 news paper article, 3 abstracts, and 88 articles in journals contributed as author/co-author. He also worked on 6 research projects as Principal Investigator and Co-investigators. He successfully supervised 2 PhD degrees, and 17 Masters students.
Education
Academic Background
Publications (73)
Selected Scholarly Contributions
Genetically Modified (GM) foods and the risk to human health and environment.
Ardekani, A.M. and M. Shirzad,
Health Biotechnol. Biopharma J.,
| Journal Article

Ali Motevalizadeh Ardekani
2019
Association of interleukin-1 gene polymorphism with risk of gastric and colorectal cancers in an Iranian population.
Abbasian, M.H., B. Abbasi, N. Ansarinejad, A.M. Ardekani, E. Samizadeh, K.G. Moghaddam and M.R. Hashemi,
Iran. J. Immunol.,
| Journal Article

Ali Motevalizadeh Ardekani
2018
Methylation status of NANOG1, RASSF1A, SFN, CASP8, WIF1, CTSL2 genes in Iranian breast cancer patients.
Ardekani, A.M., M. Shirani, A. Hashemi, Z. Basiri and Y. Rahmati et al.,
Iran. South Med. J.,
| Journal Article

Ali Motevalizadeh Ardekani
2017
Evaluation of serum interleukin-21 and HLA-C1 polymorphism in pediatrician hematopoietic stem cell transplantation for early diagnosis of acute graft-versus-host disease.
Sehati, N., P. Kokhaei, A.M. Ardekani, R. Tootoonchian and F. Pak,
Iran. Biomed. J.,
| Journal Article

Ali Motevalizadeh Ardekani
2017
Biotechnology: Two decades of experimentation with genetically modified foods.
Ajami, M., M. Alimoradi and A.M. Ardekani,
Applied Food Biotechnol.,
| Journal Article

Ali Motevalizadeh Ardekani
2016
Role of epigenetics in biology and human diseases.
Moosavi, A. and A.M. Ardekani,
Iran. Biomed. J.,
| Journal Article

Ali Motevalizadeh Ardekani
2016
The human genome project: Ethical and legal challenges in human societies.
Ardekani, A.M.Z.,
Iran. J. Bioethics,
| Journal Article

Ali Motevalizadeh Ardekani
2016
Comparison of the serum total bile acids and cholesterol levels in breast cancer patients with control group.
Fadaeipour, S., Z Babaei, H. Parsian, A.M. Ardekani and N. Nikbakhsh,
J. Babol Univ. Med. Sci.,
| Journal Article

Ali Motevalizadeh Ardekani
2016
Evaluation of interleukin 12 and CD56 + lymphocyte cells in pediatric hematopoietic stem cell transplantation for early diagnosis of acute graft versus host disease.
Tootoonchian, R., F. Pak, A.M. Ardekani, N. Sehati, M. Abedi-Valugerdi and P. Kokhaei,
Transplant Immunol.,
| Journal Article

Ali Motevalizadeh Ardekani
2016
Alcohol and women's health.
Boroumand, M. and A.M. Ardekani,
J. Social Issues Humanit.,
| Journal Article

Ali Motevalizadeh Ardekani
2015
Investigation of E-cadherin expression in peripheral blood of patients with breast cancer in a population from southern Iran.
Naemi, S., A.M. Ardekani, A. Ghaderi and N. Erfani,
Iran. South Med. J.,
| Journal Article

Ali Motevalizadeh Ardekani
2015
Serum/plasma DNA methylation pattern and early detection of breast cancer.
Gharibiyan, A., S.A. Hashemi, M. Hadi, H. Abdolghafoorian and A.M. Ardekani,
Clin. Cancer Invest. J.,
| Journal Article

Ali Motevalizadeh Ardekani
2015
Pseudo five-component synthesis of 5-phenyldihydrospiro [diindenopyridine-indenoquinoxaline] dione derivatives via a one-pot condensation reaction.
Amanpour, T., A. Bazgir, A.M. Ardekani and R. Ghahremanzadeh,
Monatshefte fur Chemie-Chem. Monthly,
| Journal Article

Ali Motevalizadeh Ardekani
2014
Variation of IL-17A and IL-17F genes in patients with breast cancer in a population from southern Iran.
Naeimi, S., N. Erfani, A.M. Ardekani and A. Ghaderi,
Adv. Environ. Biol.,
| Journal Article

Ali Motevalizadeh Ardekani
2014
Genetically modified foods and health concerns.
Ardekani, A.M.,
Iran. J. Biotechnol.,
| Journal Article

Ali Motevalizadeh Ardekani
2014
Effect of chronic restraint stress on HPA axis activity and expression of BDNF and Trkb in the hippocampus of pregnant rats: Possible contribution in depression during pregnancy and postpartum period.
Maghsoudi, N., R. Ghasemi, Z. Ghaempanah, A.M. Ardekani and E. Nooshinfar,
Basic Clin. Neurosci. J.,
| Journal Article

Ali Motevalizadeh Ardekani
2014
A bio-social review to mitigate the punishment of unwanted acts.
Alimardani, A., A.M. Ardekani and L.R. Astany,
Int. J. Criminol. Sociol.,
| Journal Article

Ali Motevalizadeh Ardekani
2014
Association study of the TNF-α-1031T/C and VEGF+450G/C polymorphisms with susceptibility to endometriosis.
Saliminejad, K., T. Memariani, A.M. Ardekani, K. Kamali, H.E.Z. Pahlevanzadeh and H.R.K. Khorshid,
Gynecol. Endocrinol.,
| Journal Article

Ali Motevalizadeh Ardekani
2013
Antioxidant and apoptotic effects of an aqueous extract of Urtica dioica on the MCF-7 human breast cancer cell line.
Fattahi, S., A.M. Ardekani, E. Zabihi, Z. Abedian, A. Mostafazadeh, R. Pourbagher and H. Akhavan-Niaki,
Asian Pac. J. Cancer Prev.,
| Journal Article

Ali Motevalizadeh Ardekani
2013
Cancer drug treatment in Persian traditional medicine sources.
Ardekani, A.M.Z., M. Hashemi, M.S. Kish, A.A. Bagheri, S.B. Shekoohi and M. Mosadegh,
Iran. Islamic Tradit. Med. J.,
| Journal Article

Ali Motevalizadeh Ardekani
2012
Non-invasive detection of esophageal cancer using genetic changes in circulating cell-free DNA.
Ghorbian, S. and A.M. Ardekani,
Avicenna J. Med. Biotechnol.,
| Journal Article

Ali Motevalizadeh Ardekani
2012
Short exposure to collagenase and coculture with mouse embryonic pancreas improve human dermal fibroblast culture.
Pandamooz, S., A. Hadipour, H. Akhavan-Niaki, M. Pourghasem and Z. Abedian et al.,
Biotechnol. Applied Biochem.,
| Journal Article

Ali Motevalizadeh Ardekani
2012
Effect of polyunsaturated fatty acids on secretory phospholipase A2 type IIa in ectopic endometrial cells.
Khanaki, K., A.M. Ardekani, A. Ghassemzadeh, V. Shahnazi and M.R. Sadeghi et al.,
Iran. J. Reprod. Med.,
| Journal Article

Ali Motevalizadeh Ardekani
2012
Prostaglandin E2 induces growth inhibition, apoptosis and differentiation in T and B cell-derived acute lymphoblastic leukemia cell lines (CCRF-CEM and Nalm-6).
Fard, S.S., M.J. Tehrani and A.M. Ardekani,
Prostaglandins Leukotrienes Essential Fatty Acids,
| Journal Article

Ali Motevalizadeh Ardekani
2012
Evaluation of the relationship between endometriosis and omega-3 and omega-6 polyunsaturated fatty acids.
Khanaki, K., M. Nouri, M. Ardekani, A. Ghassemzadeh and V. Shahnazi et al.,
Iranian Biomed. J.,
| Journal Article

Ali Motevalizadeh Ardekani
2012
Genetically modified foods and social concerns.
Maghari, B.M. and A.M. Ardekani,
Avicenna J. Med. Biotechnol.,
| Journal Article

Ali Motevalizadeh Ardekani
2011
Ethical challenges in applications of reproductive biotechnologies.
Ardekani, A.M.,
Cell J.,
| Journal Article

Ali Motevalizadeh Ardekani
2011
Frequency of familial history in population with breast cancer referred to babol educational hospitals during 2007-2010.
Abdollahpour, M., R. Tahamtan, F. Samani, Z. Deldar and M. Dehghan et al.,
Cell J.,
| Journal Article

Ali Motevalizadeh Ardekani
2011
Improved protocol for isolating dermal fibroblasts.
Pandamooz, S., H. Akhavan-Niaki, N. Mousavi Kani, Z. Abedian, A.M. Ardekani, A. Hadipour and A. Mostafazadeh,
Cell J.,
| Journal Article

Ali Motevalizadeh Ardekani
2011
Genetic privacy and genetic information of patients.
Ahmadi, M. and A.M. Ardekani,
Med. Genet. J.,
| Journal Article

Ali Motevalizadeh Ardekani
2011
Fenretinide, 1α,25(OH)2D3 and Bryostatin-1 induce cell cycle arrest, apoptosis and differentiation in human acute lymphoblastic leukemia cell lines (CCRF-CEM and Nalm-6).
Ardekani, A.M., S.S. Fard, M.J. Tehrani and R. Ghahremanzade,
Avicenna J. Med. Biotechnol.,
| Journal Article

Ali Motevalizadeh Ardekani
2011
Stress-induced proteomic changes in the hippocampus of pregnant wistar rats.
Ardekani, A.M., N. Maghsudi, A. Meyfour, R. Ghasemi, N. Lakpour, E. Nooshinfar and Z. Ghaempanah,
Avicenna J. Med. Biotechnol.,
| Journal Article

Ali Motevalizadeh Ardekani
2011
The role of miRNAs and human diseases.
Ardekani, A.M. and M. Moslemi,
Avicenna J. Med. Biotechnol.,
| Journal Article

Ali Motevalizadeh Ardekani
2010
Tyrosine phosphorylation pattern in sperm proteins isolated from normospermic and teratospermic men.
Jabbari, S., M.R. Sadeghi, M.M. Akhondi, E.H. Azadeh and N. Amirjanati et al.,
J. Reprod. Infertil.,
| Journal Article

Ali Motevalizadeh Ardekani
2010
Comparing seminal plasma biomarkers between normospermic and azoospermic men.
Soudabeh, S., A.M. Ardakani, H. Mahshid, A.M. Mehdi and S.G. Haleh et al.,
J. Reprod. Infertil.,
| Journal Article

Ali Motevalizadeh Ardekani
2010
Flow cytometric analysis of 4-HPR-induced apoptosis and cell cycle arrest in acute myelocytic leukemia cell line (NB-4).
Fard, S.S., M. Jeddi-Tehrani, M.M. Akhondi, M. Hashemi and A.M. Ardekani,
Avicenna J. Med. Biotech.,
| Journal Article

Ali Motevalizadeh Ardekani
2010
Genetics and ethical issues.
Sudabeh, J. and A.M. Ardekani,
Q. J. Med. Ethics,
| Journal Article

Ali Motevalizadeh Ardekani
2009
Gene therapy and medical ethics.
Shabnam, B. and A.M. Ardekani,
Q. J. Med. Ethics,
| Journal Article

Ali Motevalizadeh Ardekani
2009
Genetic technologies and ethics.
Ardekani, A.M.,
J. Med. Ethics Hist. Med.,
| Journal Article

Ali Motevalizadeh Ardekani
2009
Noncoding RNAs and cancer.
Naeini, M.M. and A.M. Ardekani,
Avicenna J. Med. Biotech.,
| Journal Article

Ali Motevalizadeh Ardekani
2009
Nutrigenomics and cancer.
Ardekani, A.M. and S. Jabbari,
Avicenna J. Med. Biotech.,
| Journal Article

Ali Motevalizadeh Ardekani
2009
Genetic behavior and culture.
Ardekani, A.M.,
Med. Ethics J.,
| Journal Article

Ali Motevalizadeh Ardekani
2009
Application of genomic and proteomic technologies to early detection of cancer.
Ardekani, A.M., M.M. Akhondi and M.R. Sadeghi,
Arch. Iran. Med.,
| Journal Article

Ali Motevalizadeh Ardekani
2008
Influence of the probiotic escherichia coli strain Nissle 1917 on the growth of different pathogenic bacteria isolated from patients with diarrhea.
Dezfulian, A., A.M.Z. Ardekani, M.M. Aslani, H. Dabiri and M.R. Zali,
Gastroenterol. Hepatol. Bed Bench,
| Journal Article

Ali Motevalizadeh Ardekani
2008
Application of genomics and proteomics technologies to early detection of cancer.
Ardekani, A.M., M.M. Akhondi and M.R. Sadeghi,
Arch. Iran Med.,
| Journal Article

Ali Motevalizadeh Ardekani
2008
Application of genomics and proteomics technologies to early diagnosis of reproductive organ cancers.
Ardekani, A.M., A. Ferial and N. Lakpour,
J. Reprod. Infertil.,
| Journal Article

Ali Motevalizadeh Ardekani
2007
Toxicoproteomics: Serum proteomic pattern diagnostics for early detection of drug induced cardiac toxicities and cardioprotection.
Petricoin, E.F., V. Rajapaske, E.H. Herman, A.M. Ardekani and S. Ross et al.,
Toxicol. Pathol.,
| Journal Article

Ali Motevalizadeh Ardekani
2004
Molecular diagnostics: An FDA perspective.
Ardekani, A.M., E.F. Petricoin and J. Hackett,
Expert Rev. Mol. Diag.,
| Journal Article

Ali Motevalizadeh Ardekani
2003
General keynote: Proteomic patterns in sera serve as biomarkers of ovarian cancer.
Liotta, L.A., E.F. Petricoin, A.M. Ardekani, B.A. Hitt and P.J. Levine, et al.,
Gynecologic Oncol.,
| Journal Article

Ali Motevalizadeh Ardekani
2003
Clinical potential of proteomics in the diagnosis of ovarian cancer.
Ardekani, A.M., L.A. Liotta and E.F. Petricoin,
Expert Rev. Mol. Diagn.,
| Journal Article

Ali Motevalizadeh Ardekani
2002
Use of proteomic patterns in serum to identify ovarian cancer.
Petricoin, E.F., A.M. Ardekani, B.A. Hitt, P.J. Levine and V.A. Fusaro et al.,
Lancet,
| Journal Article

Ali Motevalizadeh Ardekani
2002
Serum proteomic patterns for detection of prostate cancer.
Petricoin, E.F., D.K. Ornstein, C.P. Paweletz, A. Ardekani and P.S. Hackett et al.,
J. Natl. Cancer Inst.,
| Journal Article

Ali Motevalizadeh Ardekani
2002
Genomics and proteomics: Application of novel technology to early detection and prevention of cancer.
Michener, C.M., A.M. Ardekani, E.F. Petricoin, L.A. Liotta and E.C. Kohn,
Cancer Detection Prev.,
| Journal Article

Ali Motevalizadeh Ardekani
2002
Proteomic technologies to study diseases of the lymphatic vascular system.
Leak, L.V., E.F. Petricoin, M. Jones, C.P. Paweletz and A.M. Aredekani et al.,
Ann. N.Y. Acad. Sci.,
| Journal Article

Ali Motevalizadeh Ardekani
2002
Molecular profiling of cancer and drug-induced toxicity using new proteomics technologies.
Ardekani, A.M., E.H. Herman, F.D. Sistare, L.A. Liotta and E.F. Petricoin,
Curr. Ther. Res.,
| Journal Article

Ali Motevalizadeh Ardekani
2001
Two repressor elements inhibit expression of the von willebrand factor gene promoter in vitro.
Ardekani, A.M., J.S. Greenberger and N. Jahroudi,
Thromb. Homeost.,
| Journal Article

Ali Motevalizadeh Ardekani
1998
Structure of the rat inhibin and activin βA-subunit gene and regulation in an ovarian granulosa cell line.
Ardekani, A.M., J.C. Romanelli and K.E. Mayo,
Endocrinology,
| Journal Article

Ali Motevalizadeh Ardekani
1998
Regulation of inhibin and activin subunit gene expression in ovarian granulosa cells.
Mayo, K.E., A. Mukherjee, A. Ardekani and I.W. Shu,
Biol. Reprod.,
| Journal Article

Ali Motevalizadeh Ardekani
1997
New solid culture media for growing borrelia persica and borrelia microti.
Bahrmand, A.R., H. Nekoui and A.M. Ardekani,
Rev. Cubana Med. Trop.,
| Journal Article

Ali Motevalizadeh Ardekani
1996
Ionizing irradiation increases transcription of the von willebrand factor gene in endothelial cells.
Jahroudi, N., A.M. Ardekani and J.S. Greenberger,
Blood,
| Journal Article

Ali Motevalizadeh Ardekani
1996
An NF1-like protein functions as a repressor of the von Willedbrand factor promoter.
Jahroudi, N., A.M. Ardekani and J.S. Greenberger,
J. Biol. Chem.,
| Journal Article

Ali Motevalizadeh Ardekani
1996
Two repressor elements regulate endothelial-specific activation of the VWF promoter.
Jahroudi, N., A. Ardekani and J.S. Greenberger,
Blood,
| Journal Article

Ali Motevalizadeh Ardekani
1996
The von-willebrand-factor gene-transcription is increased in response to ionizing irradiation.
Jahroudi, N., A. Ardekani and J.S. Greenberger,
Exp. Hematol.,
| Journal Article

Ali Motevalizadeh Ardekani
1995
Ionizing irradiation increases transcription of the von willebrand factor gene in endothelial cells.
Jahroudi, N., A. Ardekani and J.S. Greenberger,
Blood,
| Journal Article

Ali Motevalizadeh Ardekani
1995
An NF-1-like protein functions as a repressor of the vWf promoter.
Jahroudi, N., A. Ardekani and J.S. Greenberger,
Blood,
| Journal Article

Ali Motevalizadeh Ardekani
1995
Luminol-or lucigenin-coated micropolystyrene beads, a single reagent to study opsonin-independent phagocytosis by cellular chemiluminescence: Reaction with human neutrophils, monocytes and differentiated HL-60 cells.
Van Dyke, K., P. Allender, L. Wu, J. Gutierrez, J. Garcia, A.M. Ardekani and W. Karo,
Microchem. J.,
| Journal Article

Ali Motevalizadeh Ardekani
1990
Luminol or lucigenin-coated polystyrene beads, a single reagent to study opsonin independent phagocytosis by cellular L-60 cells.
Van Dyke, K., P. Allender, L. Wu, J. Gutierrez, J. Garcia, A.M. Ardekani and W. Karo,
Microchem. J.,
| Journal Article

Ali Motevalizadeh Ardekani
1990
Adrenocorticotropin and corticosterone levels in pre-weaning spontaneously hypertensive rats.
Ardekani, A.M., S.J. Walker, S.J. Donohue, R.E. Stitzel, J.M. Conners and K.E. Vrana,
Life Sci.,
| Journal Article

Ali Motevalizadeh Ardekani
1989
Myeloperoxidase involvement in PMA induced chemiluminescence in retinoic-acid-differentiated HL-60 cells.
Ardekani, A.M. and K. Van Dyke,
Microchem. J.,
| Journal Article

Ali Motevalizadeh Ardekani
1989
Chemiluminescent response in murine peritoneal macrophage hybridoma-cell line (2C11-12) primed with lipopolysaccharide (LPS) and Interferon-β.
Ardekani, A.M., P. de Baetselier and K. Van Dyke,
Microchem. J.,
| Journal Article

Ali Motevalizadeh Ardekani
1989
Diminished chemiluminescent responses of polymorphonuclear leukocytes in preterm and very low birthweight neonates.
Peden, D., K. van Dyke, A. Ardekani, M. Mullett, D. Myerberg and C. van Dyke,
J. Pediatrics,
| Journal Article

Ali Motevalizadeh Ardekani
1987
Studies of neonatal polymorphonuclear leukocyte function using a novel microanalytic chemiluminescence technique.
Peden, D., K. van Dyke, A. Ardekani, M. Mullett and W. Neal,
Microchem. J.,
| Journal Article

Ali Motevalizadeh Ardekani
1986
The inhibition of luminol-dependent chemiluminescence of lipoxygenase, myeloperoxidase and human neutrophils by dipyridamole.
Ardekani, A.M., D. English and K. van Dyke,
Microchem. J.,
| Journal Article

Ali Motevalizadeh Ardekani
1986