Education
Academic Background-
Ph.D. Universiti Putra Malaysia, Malaysia Pharmacology | Completed: 2010
Publications (108)
Selected Scholarly Contributions
Design, synthesis, and preliminary anticancer evaluation of diphenylpropan-1-one derivatives:
in vitro
,
in vivo
and
in silico
studies
2026
Extraction and Applications of Oakmoss Absolute Extract as a Functional Ingredient in Alginate‐Guar Gum Composite Films for Food Packaging
2025
Potential role of immunotherapy and targeted therapy in the treatment of cancer: A contemporary nursing practice
2024
2024
Phytoimmunomodulators: A review of natural modulators for complex immune system
2024
Role of ferroptosis pathways in neuroinflammation and neurological disorders: From pathogenesis to treatment
2024
2024
Examining the potential of peppermint essential oil-infused pectin and kappa-carrageenan composite films for sustainable food packaging
2024
Cetuximab-conjugated sodium selenite nanoparticles for doxorubicin targeted delivery against MCF-7 breast cancer cells
2024
The sub-acute toxicity of kavalactone in rats: a study of the effect of oral doses and the mechanism of toxicity in combination with ethanol
2023
Spectral analysis, in vitro cytotoxicity and antibacterial studies of bioactive principles from the leaves of Conocarpus lancifolius, a common tree of Jazan, Saudi Arabia
2023
GC‐MS Phytochemical Profiling, Antidiabetic, and Antioxidant Activities of Khaya senegalensis Stem Bark and Azadirachta indica Leaves Extracts in Rats
2023
Comprehensive Review on Synthesis, Applications, and Challenges of Graphene Quantum Dots (GQDs)
2023
Antifungal Activity of Plant Secondary Metabolites on Candida albicans: An Updated Review
2023
Unveiling the Pharmacological and Nanotechnological Facets of Daidzein: Present State-of-the-Art and Future Perspectives
2023
Biodegradable Electrospun Scaffolds as an Emerging Tool for Skin Wound Regeneration: A Comprehensive Review
2023
Vitamin E TPGS-Based Nanomedicine, Nanotheranostics, and Targeted Drug Delivery: Past, Present, and Future
2023
One-pot green synthesis of silver nanoparticles using brittle star Ophiocoma scolopendrina: Assessing biological potentialities of antibacterial, antioxidant, anti-diabetic and catalytic degradation of organic dyes
2023
One-pot green synthesis of gold nanoparticles using Sarcophyton crassocaule, a marine soft coral: Assessing biological potentialities of antibacterial, antioxidant, anti-diabetic and catalytic degradation of toxic organic pollutants
2023
Improvement in the Phytochemical Content and Biological Properties of Stevia rebaudiana (Bertoni) Bertoni Plant Using Endophytic Fungi Fusarium fujikuroi
2023
Structural Complementarity of Bruton’s Tyrosine Kinase and Its Inhibitors for Implication in B-Cell Malignancies and Autoimmune Diseases
2023
Mitochondrial Dysfunction: A Cellular and Molecular Hub in Pathology of Metabolic Diseases and Infection
2023
TRP channels: Role in neurodegenerative diseases and therapeutic targets
2023
Broccoli: A Multi-Faceted Vegetable for Health: An In-Depth Review of Its Nutritional Attributes, Antimicrobial Abilities, and Anti-inflammatory Properties
2023
Exploring LIPIDs for their potential to improves bioavailability of lipophilic drugs candidates: A review
2023
Spectral characterization and biological evaluation of biomolecules from the peels of three orange fruits: a comparative study
2022
Mechanistic Insights Expatiating the Redox-Active-Metal-Mediated Neuronal Degeneration in Parkinson’s Disease
2022
Theranostic Nanomedicines for the Treatment of Cardiovascular and Related Diseases: Current Strategies and Future Perspectives
2022
Development and Characterization of Chitosan and Porphyran Based Composite Edible Films Containing Ginger Essential Oil
2022
Correction: Al-Harrasi et al. Development and Characterization of Chitosan and Porphyran Based Composite Edible Films Containing Ginger Essential Oil. Polymers 2022, 14, 1782
2022
Effect of Drying Temperature on Physical, Chemical, and Antioxidant Properties of Ginger Oil Loaded Gelatin-Sodium Alginate Edible Films
2022
Phytoconstituents Assisted Biofabrication of Copper Oxide Nanoparticles and Their Antiplasmodial, and Antilarval Efficacy: A Novel Approach for the Control of Parasites
2022
Decrypting the Potential of Nanotechnology-Based Approaches as Cutting-Edge for Management of Hyperpigmentation Disorder
2022
Applications of Adductomics in Chemically Induced Adverse Outcomes and Major Emphasis on DNA Adductomics: A Pathbreaking Tool in Biomedical Research
2021
Documentation of bioactive principles of the exudate gel (EG) from the stem of Caralluma retrospiciens (Ehrenb) and in vitro antibacterial activity – Part A
2020
An Overview of In Vitro, In Vivo, and Computational Techniques for Cancer‐Associated Angiogenesis Studies
2020
Antileukemic Effect of Palladium Nanoparticles Mediated by White Tea (Camellia sinensis) Extract In Vitro and in WEHI‐3B‐Induced Leukemia In Vivo
2020
Gefitinib loaded nanostructured lipid carriers: Characterization, evaluation and anti-human colon cancer activity in vitro.
Syam Mohan Murali
2020
Girinimbine from curry leaves promotes gastro protection against ethanol induced peptic ulcers and improves healing via regulation of anti-inflammatory and antioxidant mechanisms.
Syam Mohan Murali
2020
An anti-inflammatory molecular mechanism of action of α-mangostin, the major xanthone from the pericarp of Garcinia mangostana: an in silico, in vitro and in vivo approach
2018
Khat Induced Toxicity: Role on Its Modulating Effects on Inflammation and Oxidative Stability
2018
Khat (Catha edulisForsk.) Dependence Potential and Pattern of Use in Saudi Arabia
2015
A Phenylbutenoid Dimer,cis-3-(3′,4′-Dimethoxyphenyl)-4-[(E)-3′′′,4′′′-Dimethoxystyryl] Cyclohex-1-ene, Exhibits Apoptogenic Properties in T-Acute Lymphoblastic Leukemia Cells via Induction of p53-Independent Mitochondrial Signalling Pathway
2013
Inclusion Complex of Zerumbone with Hydroxypropyl-β-Cyclodextrin Induces Apoptosis in Liver Hepatocellular HepG2 Cells via Caspase 8/BID Cleavage Switch and Modulating Bcl2/Bax Ratio
2013
α-Mangostin fromCratoxylum arborescens(Vahl) Blume Demonstrates Anti-Ulcerogenic Property: A Mechanistic Study
2013
Boesenbergin A, a chalcone from Boesenbergia rotunda induces apoptosis via mitochondrial dysregulation and cytochrome c release in A549 cells in vitro: Involvement of HSP70 and Bcl2/Bax signalling pathways.
Syam Mohan Murali
2013
Pyranocycloartobiloxanthone A, a novel gastroprotective compound from Artocarpus obtusus Jarret, against ethanol-induced acute gastric ulcer in vivo.
Syam Mohan Murali
2013
Thymoquinone induces mitochondria-mediated apoptosis in acute lymphoblastic leukaemia in vitro.
Syam Mohan Murali
2013
Dentatin isolated from Clausena excavata induces apoptosis in MCF-7 cells through the intrinsic pathway with involvement of NF-κB signalling and G0/G1 cell cycle arrest: A bioassay-guided approach.
Syam Mohan Murali
2013
Erectogenic Effects ofClerodendron capitatum: Involvement of Phosphodiesterase Type-5 Inhibition
2012
In vitro anti-inflammatory, cytotoxic and antioxidant activities of boesenbergin A, a chalcone isolated from Boesenbergia rotunda (L.) (fingerroot).
Syam Mohan Murali
2012
Clausena excavate Burm. f. (Rutaceae): A review of its traditional uses, pharmacological and phytochemical properties.
Syam Mohan Murali
2012
In vitro and in vivo anti-inflammatory activities of columbin through the inhibition of cycloxygenase-2 and nitric oxide but not the suppression of NF-κB translocation.
Syam Mohan Murali
2012
2012
Involvement of NF-κB and Bcl2/Bax signaling pathways in the apoptosis of MCF7 cells induced by a xanthone compound Pyranocycloartobiloxanthone A.
Syam Mohan Murali
2012
Hibiscus vitifolius (Linn.) root extracts shows potent protective action against anti-tubercular drug induced hepatotoxicity.
Syam Mohan Murali
2012
Growth suppressing effect of girinimbine in HepG2 involves induction of apoptosis and cell cycle arrest.
Syam Mohan Murali
2011
The methanolic extract of Boesenbergia rotunda (L.) Mansf. and its major compound inostrobin induces anti-ulcerogenic property in vivo: Possible involvement of indirect antioxidant action.
Syam Mohan Murali
2011
Preparation and characterisation of gelatins from two sudanese edible insects.
Syam Mohan Murali
2011
The methanolic extract of Boesenbergia rotunda (L.) Mansf. and its major compound pinostrobin induces anti-ulcerogenic property in vivo: Possible involvement of indirect antioxidant action.
Syam Mohan Murali
2011
Anti-inflammatory activities of cucurbitacin E isolated from Citrullus lanatus var. citroides: Role of reactive nitrogen species and cyclooxygenase enzyme inhibition.
Syam Mohan Murali
2011
Growth suppressing effect of girinimbine in HepG2 involves induction of apoptosis and cell cycle arrest.
Syam Mohan Murali
2011
The methanolic extract of Boesenbergia rotunda (L.) Mansf. and its major compound inostrobin induces anti-ulcerogenic property in vivo: Possible involvement of indirect antioxidant action.
Syam Mohan Murali
2011
Zerumbone induces apoptosis in T-acute lymphoblastic leukemia cells.
Syam Mohan Murali
2011
Pharmacognostical and preliminary phytochemical screening the leaves of Jasminum grandiflorum Linn.
Syam Mohan Murali
2010
Attenuation of cisplatin-induced nephrotoxicity in rats using zerumbone.
Syam Mohan Murali
2010
Evaluation of acute toxicity and the effect of single injected doses of zerumbone on the kidney and liver functions in Sprague Dawley rats.
Syam Mohan Murali
2010
Typhonium flagelliforme induces apoptosis through mitochondrial pathway.
Syam Mohan Murali
2010
Pharmacognostical and preliminary phytochemical screening the leaves of Jasminum grandiflorum Linn.
Syam Mohan Murali
2010
Attenuation of cisplatin-induced nephrotoxicity in rats using zerumbone.
Syam Mohan Murali
2010
Evaluation of acute toxicity and the effect of single injected doses of zerumbone on the kidney and liver functions in Sprague Dawley rats.
Syam Mohan Murali
2010
Potential chemoprevention of diethylnitrosamine-initiated and 2-acetylaminofluorene-promoted hepatocarcinogenesis by zerumbone from the rhizomes of the subtropical ginger (Zingiber zerumbet).
Syam Mohan Murali
2010
Evaluation of the genotoxicity of zerumbone in cultured human peripheral blood lymphocytes.
Syam Mohan Murali
2010
Typhonium flagelliforme inhibits the proliferation of murine leukemia WEHI-3 cells in vitro and induces apoptosis in vivo.
Syam Mohan Murali
2010
Typhonium flagelliforme induces apoptosis in CEMss cells via activation of caspase-9, PARP cleavage and cytochrome C release: Its activation coupled with G0/G1 phase cell cycle arrest.
Syam Mohan Murali
2010
Typhonium flagelliforme induces apoptosis through mitochondrial pathway.
Syam Mohan Murali
2010
In vivo and in vitro genotoxic effects of zerumbone.
Syam Mohan Murali
2010
Regression of cervical intraepithelial neoplasia by zerumbone in female Balb/c mice prenatally exposed to diethylstilboestrol: Involvement of mitochondria-regulated apoptosis.
Syam Mohan Murali
2010
Biological activities of peresika bleo extracts.
Syam Mohan Murali
2009
GC/MS determination of bioactive components and antibacterial properties of Goniothalamus umbrosus extracts.
Syam Mohan Murali
2009
Attenuation of cisplatin-induced hepatotoxicity in rats using zerumbone.
Syam Mohan Murali
2009
Antimicrobial and free radical scavenging activities of the dichloromethane extract of Goniothalamus umbrosus.
Syam Mohan Murali
2009
Oncolysis of breast, liver and leukemia cancer cells using ethyl acetate and methanol extracts of Goniothalamus umbrosus.
Syam Mohan Murali
2009
In vitro response of cancer cells to the growth inhibitory effects of Dichloromethane extract of Goniothalamus umbrosus.
Syam Mohan Murali
2009
2009
In vitro response of cancer cells to the growth-inhibitory effects of dichloromethane extract of Goniothalamus umbrosus.
Syam Mohan Murali
2009
Biological activities of peresika bleo extracts.
Syam Mohan Murali
2009
GC/MS determination of bioactive components and antibacterial properties of Goniothalamus umbrosus extracts.
Syam Mohan Murali
2009
Antidiarrhoeal activity of leaves of Melastoma malabathricum Linn.
Syam Mohan Murali
2009
Antimicrobial and free radical scavenging activities of the dichloromethane extract of Goniothalamus umbrosus.
Syam Mohan Murali
2009
Oncolysis of breast, liver and leukemia cancer cells using ethyl acetate and methanol extracts of Goniothalamus umbrosus.
Syam Mohan Murali
2009
Antidiabetic activity of momordica tuberosa (Roxb.) cogn Tuber extracts.
Syam Mohan Murali
2008
Antibacterial and antioxidant activities of Typhonium flagelliforme (Lodd.) blume leaves.
Syam Mohan Murali
2008
Antioxidant and hepatoprotective effect of the roots of Hibiscus esculentus Linn.
Syam Mohan Murali
2008
Antitumour activity of Hibiscus tiliaceus Linn. Roots.
Syam Mohan Murali
2008
Anticancerous effect of Typhonium flagelliforme on human t4-lymphoblastoid cell line CEM-ss.
Syam Mohan Murali
2008
Antidiabetic activity of momordica tuberosa (Roxb.) cogn Tuber extracts.
Syam Mohan Murali
2008
Anticancerous effect of Typhonium flagelliforme on human T4-lymphoblastoid cell line CEM-ss.
Syam Mohan Murali
2008
Antibacterial and antioxidant activities of Typhonium flagelliforme (Lodd.) blume leaves.
Syam Mohan Murali
2008
Zerumbone: A natural compound with anti-cholinesterase activity.
Syam Mohan Murali
2008
Antioxidant and hepatoprotective effect of the roots of Hibiscus esculentus Linn.
Syam Mohan Murali
2008
Antibacterial and antioxidant activities of Typhonium flagelliforme (Lodd.) blume tuber.
Syam Mohan Murali
2008
Anti-tumor activities of analogues derived from the bioactive compound of Zingiber zerumbet.
Syam Mohan Murali
2008
Anticancer and antimicrobial activities of zerumbone from the rhizomes of Zingiber zerumbut.
Syam Mohan Murali
2008
The establishment and use of an in vivo animal model for cervical intra-epithelial neoplasia.
Syam Mohan Murali
2008
Anticancer activity of natural compound (Zerumbone) extracted from Zingiber zerumbet in human hela cervical cancer cells.
Syam Mohan Murali
2008
Wound healing activity of jasminum sambac leaf extract.
Syam Mohan Murali
2004
Wound healing activity of jasminum sambac leaf extract.
Syam Mohan Murali
2004