About
Professional Summary
Mr. Nikhil Baban Ghate is currently working as Senior Research Fellow at Bose Institute, India. He has completed his M.Sc./M.Sc. (Hons.) in Biotechnology from University of Pune, Pune, India. He is dynamic research Biologist/Chemist with exposure in free Radical Imbalance and the Pathological Consequences thereof. His area of research interest focuses on different aspects of Alternative Medicines with special emphasis on Development of Anticancer as well as Anti-Inflammatory Drugs. He has hands-on experience on In-vitro as well as In-vivo techniques, and 3+ years of lab‐based training in Cell Biology, Molecular Biology and Biochemistry of Cancer Prognosis and Therapeutics, Esp. Alternative Approaches. He also worked on 3 research projects. He has published 23 research articles in journals and 9 research achievement published in news media contributed as author/co-author. He is also serving as peer reviewer for Pharmaceutical Biology and BMC Biological Research.
Education
Academic Background
Editorial Services
Editorial & Publishing Roles
Editorial Board Member
Jul 2019 — Present
Serving as Editorial Board Member for International Journal of Cancer Research.
Editorial Board Member
Jul 2019 — Present
Serving as Editorial Board Member for Asian Journal of Cell Biology.
Editorial Board Member
Jul 2019 — Present
Serving as Editorial Board Member for Journal of Pharmacology and Toxicology.
Editorial Board Member
Jul 2019 — Present
Serving as Editorial Board Member for American Journal of Biochemistry and Molecular Biology.
Publications (22)
Selected Scholarly Contributions
B1486 is a highly potent VprBP inhibitor capable of blocking osteoclast differentiation and bone resorption
Sungmin Kim, Yonghwan Shin, Nikhil B. Ghate, Woojin An
Journal of Biological Chemistry
| Journal Article
2026
The multifaceted role of PUMA in cell death pathways: its therapeutic potential across cancer types
Sharad Shriram Tat, Kartik Mandal, Tanisha Sharma, Nikhil Baban Ghate, Ganesh Kumar Barik, Rajesh N. Gachhe, Manas Kumar Santra
Cell Communication and Signaling
| Journal Article
2025
Ameliorating effects of white mulberry on iron-overload-induced oxidative stress and liver fibrosis in Swiss albino mice
Anil Khushalrao Shendge, Sourav Panja, Tapasree Basu, Nikhil Baban Ghate, Nripendranath Mandal
Food and Chemical Toxicology
| Journal Article
2021
VprBP directs epigenetic gene silencing through histone H2A phosphorylation in colon cancer.
Ghate, N.B., S. Kim, E. Spiller, S. Kim and Y. Shin et al.,
Mol. Oncol.,
| Journal Article
Nikhil Baban Ghate
2021
p32 is a negative regulator of p53 tetramerization and transactivation.
Ghate, N.B., J. Kim, Y. Shin, A. Situ, T.S. Ulmer and W. An,
Mol. Oncol.,
| Journal Article
Nikhil Baban Ghate
2019
In vitro mechanistic study of the anti-inflammatory activity of a quinoline isolated from Spondias pinnata bark.
Ghate, N.B., D. Chaudhuri, S. Panja, S.S. Singh, G. Gupta, C.Y. Lee and N. Mandal,
J. Nat. Prod.,
| Journal Article
Nikhil Baban Ghate
2018
Antioxidant and antiproliferative effects of different solvent fractions from Terminalia belerica Roxb. fruit on various cancer cells.
Basu, T., S. Panja, N.B. Ghate, D. Chaudhuri and N. Mandal,
Cytotechnology,
| Journal Article
Nikhil Baban Ghate
2017
Novel BODIPY-based Ru(II) and Ir(III) metalla-rectangles: Cellular localization of compounds and their antiproliferative activities.
Gupta, G., A. Das, N.B. Ghate, T. Kim and J.Y. Ryu et al.,
Chem. Commun.,
| Journal Article
Nikhil Baban Ghate
2016
Nerium indicum leaf alleviates iron- induced oxidative stress and hepatic injury in mice.
Ghate, N.B., D. Chaudhuri and N. Mandal,
Pharma. Biol.,
| Journal Article
Nikhil Baban Ghate
2015
Attenuation of iron overload induced liver toxicity by Hemidesmus indicus root in Swiss albino mice.
Hazra, B., R. Sarkar, D. Chaudhuri, N.B. Ghate, S. Panja and N. Mandal,
Int. J. Pharma. Bio Sci.,
| Journal Article
Nikhil Baban Ghate
2015
Methyl gallate isolated from Spondias pinnata exhibits anticancer activity against human glioblastoma by induction of apoptosis and sustained extracellular signal-regulated kinase 1/2 activation.
Chaudhuri, D., N.B. Ghate, S.S. Singh and N. Mandal,
Pharmacogn. Mag.,
| Journal Article
Nikhil Baban Ghate
2015
Protective effect of Clerodendrum colebrookianum leaves against iron-induced oxidative stress and hepatotoxicity in Swiss albino mice.
Das, A., D. Chaudhuri, N.B. Ghate, S. Panja, A. Chatterjee and N. Mandal,
Indian J. Exp. Biol.,
| Journal Article
Nikhil Baban Ghate
2015
Phytochemical Analysis, Antioxidant and Anticancer Potential of Leaf Extracts from Edible Greater Yam, Dioscorea alata L., from North-East India.
Das, A., D. Chaudhuri, N.B. Ghate, A. Chatterjee and N. Mandal,
Int. J. Phytopharmacol.,
| Journal Article
Nikhil Baban Ghate
2014
Heartwood Extract of Acacia catechu Induces Apoptosis in Human Breast Carcinoma by Altering Bax/Bcl-2 ratio.
Ghate, N.B., B. Hazra, R. Sarkar and N. Mandal,
Pharmacognosy Magazine,
| Journal Article
Nikhil Baban Ghate
2014
In vitro anticancer activity of Spondias pinnata bark on human lung and breast carcinoma.
Ghate, N.B., B. Hazra, R. Sarkar and N. Mandal,
Cytotechnology,
| Journal Article
Nikhil Baban Ghate
2014
In vitro assessment of phytochemicals, antioxidant and DNA protective potential of wild edible fruit Elaeagnus latifolia Linn.
Panja, S., D. Chaudhuri, N.B. Ghate, H.L. Minh and N. Mandal,
Fruits,
| Journal Article
Nikhil Baban Ghate
2014
Phytochemical profile of a microalgae Euglena tuba and its hepatoprotective effect against iron-induced liver damage in Swiss albino mice.
Panja, S., D. Chaudhuri, N.B. Ghate and N. Mandal,
J. Appl. Microbiol.,
| Journal Article
Nikhil Baban Ghate
2014
Alteration of Bax/Bcl-2 ratio contributes to Terminalia belerica-induced apoptosis in human lung and breast carcinoma.
Ghate, N.B., B. Hazra, R. Sarkar, D. Chaudhuri and N. Mandal,
<i>In vitro</i> Cell. Dev. Biol. Anim.,
| Journal Article
Nikhil Baban Ghate
2014
In vitro assessment of Tinospora cordifolia stem for its antioxidant, free radical scavenging and DNA protective potentials.
Ghate, N.B., D. Chaudhuri and N. Mandal,
Int. J. Pharma. Bio Sci.,
| Journal Article
Nikhil Baban Ghate
2013
Comparative Assessment of Phytochemicals and Antioxidant Potential of Methanolic and Aqueous Extracts of Clerodendrum colebrookianum Walp. leaf from North-East India.
Das, A., D. Chaudhuri, N.B. Ghate, A. Chatterjee and N. Mandal,
Int. J. Pharm. Pharma. Sci.,
| Journal Article
Nikhil Baban Ghate
2013
Study on the protective effects of Katha (Heartwood extract of Acacia catechu) in iron-overload-induced liver damage.
Hazra, B., R. Sarkar, N.B. Ghate, D. Chaudhuri and N. Mandal,
J. Environ. Pathol. Toxicol. Oncol.,
| Journal Article
Nikhil Baban Ghate
2013
Phytochemical Analysis and Evaluation of Antioxidant and Free Radical Scavenging Activity of Withania Somnifera Root.
Chaudhuri, D., N.B. Ghate, R. Sarkar and N. Mandal,
Asian J. Pharma. Clin. Res.,
| Journal Article
Nikhil Baban Ghate
2012
