Education
Academic Background-
Ph.D. National Taiwan University, Taiwan Pharmacology | Completed: 2000
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M.S. Kaohsiung Medical College, Taiwan Pharmacology | Completed: 1993
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B.S. Kaohsiung Medical College, Taiwan Pharmacy | Completed: 1991
Publications (276)
Selected Scholarly Contributions
Ugonin U stimulates NLRP3 inflammasome activation and enhances inflammasome-mediated pathogen clearance.
Tsong-Long Hwang
2016
Anti-allergic potential of Typhonium blumei: Inhibition of degranulation via suppression of PI3K/PLCγ2 phosphorylation and calcium influx.
Tsong-Long Hwang
2016
Four new compounds from edible algae Cladosiphon okamuranus and Chlorella sorokiniana and their bioactivities.
Tsong-Long Hwang
2016
Zoanthamine-type alkaloids from the zoanthid Zoanthus kuroshio collected in Taiwan and their effects on inflammation.
Tsong-Long Hwang
2016
Bioactive steroids from the formosan soft coral Umbellulifera petasites.
Tsong-Long Hwang
2016
Pubinernoid A and Apo-9'-fucoxanthinone, secondary metabolites from a gorgonian coral Pinnigorgia sp.
Tsong-Long Hwang
2016
Halogenated sesquiterpenoids from the red Alga Laurencia tristicha collected in Taiwan.
Tsong-Long Hwang
2016
2016
Tetranortriterpenes and limonoids from the roots of Aphanamixis polystachya.
Tsong-Long Hwang
2016
New marine sterols from an algal-bearing gorgonian coral Pinnigorgia sp.
Tsong-Long Hwang
2016
Chemical constituents of the rhizomes of Bletilla formosana and their potential anti-inflammatory activity.
Tsong-Long Hwang
2016
Marine natural product inhibitors of neutrophil-associated inflammation.
Tsong-Long Hwang
2016
Formyl peptide receptor modulators: A patent review and potential applications for inflammatory diseases (2012-2015).
Tsong-Long Hwang
2016
The potential impacts of formyl peptide receptor 1 in inflammatory diseases.
Tsong-Long Hwang
2016
New cytotoxic and anti-inflammatory steroids from the soft coral Klyxum flaccidum.
Tsong-Long Hwang
2016
Bioactive isoprenoid-derived natural products from a dongsha atoll soft coral Sinularia erecta.
Tsong-Long Hwang
2016
Pinnigorgiols A-C, 9,11-secosterols with a rare ring arrangement from a gorgonian coral Pinnigorgia sp.
Tsong-Long Hwang
2016
Constituents of the leaves of Pandanus utilis.
Tsong-Long Hwang
2016
Chemical constituents and LC-profile of fresh Formosan Lonicera japonica flower buds.
Tsong-Long Hwang
2016
3-Methyl-4,5-dihydro-oxepine, polyoxygenated seco-cyclohexenes and cyclohexenes from Uvaria flexuosa and their anti-inflammatory activity.
Tsong-Long Hwang
2016
Anti-inflammatory neolignans from the roots of Magnolia officinalis.
Tsong-Long Hwang
2016
New flavones, a 2-(2-phenylethyl)-4H-chromen-4-one derivative, and anti-inflammatory constituents from the stem barks of Aquilaria sinensis.
Tsong-Long Hwang
2015
New anti-inflammatory tocopherol-derived metabolites from the Taiwanese soft coral Cladiella hirsute.
Tsong-Long Hwang
2015
Chemical constituents from the fruiting bodies of Hexagonia apiaria and their anti-inflammatory activity.
Tsong-Long Hwang
2015
Bioactive chemical constituents from the brown alga Homoeostrichus formosana.
Tsong-Long Hwang
2015
Capsisteroids A-F, withanolides from the leaves of Solanum capsicoides.
Tsong-Long Hwang
2015
Steroidal and α-tocopherylhydroquinone glycosides from two soft corals Cladiella hirsuta and Sinularia nanolobata.
Tsong-Long Hwang
2015
Alkaloids from Pandanus amaryllifolius: Isolation and their plausible biosynthetic formation.
Tsong-Long Hwang
2015
Osthol attenuates neutrophilic oxidative stress and hemorrhagic shock-induced lung injury via inhibition of phosphodiesterase 4.
Tsong-Long Hwang
2015
Total synthesis of cordatanine, structural reassignment of drymaritin and anti-inflammatory activity of synthetic precursors.
Tsong-Long Hwang
2015
Biphenyl-type neolignan derivatives from the twigs of Magnolia denudata and their anti-inflammatory activity.
Tsong-Long Hwang
2015
Randainins A-D, based on unique diterpenoid architectures, from Callicarpa randaiensis.
Tsong-Long Hwang
2015
Neutrophil elastase inhibitors: A patent review and potential applications for inflammatory lung diseases (2010-2014).
Tsong-Long Hwang
2015
Natural Caryophyllane sesquiterpenoids from Rumphella antipathies.
Tsong-Long Hwang
2015
Anti-inflammatory and cytotoxic components from Dichrocephala integrifolia.
Tsong-Long Hwang
2015
Eunicellin-based diterpenoids, hirsutalins S-V, from the formosan soft coral Cladiella hirsuta.
Tsong-Long Hwang
2015
New coumarin derivatives and other constituents from the stem bark of Zanthoxylum avicennae: Effects on neutrophil pro-inflammatory responses.
Tsong-Long Hwang
2015
Mitochondrial Lon protease controls ROS-dependent apoptosis in cardiomyocyte under hypoxia.
Tsong-Long Hwang
2015
Anti-inflammatory and cytotoxic compounds from Solanum macaonense.
Tsong-Long Hwang
2015
Discovery of Benzo[f]indole-4,9-dione derivatives as new types of anti-inflammatory agents.
Tsong-Long Hwang
2015
Cationic liposomes evoke proinflammatory mediator release and Neutrophil Extracellular Traps (NETs) toward human neutrophils.
Tsong-Long Hwang
2015
The impact of cationic solid lipid nanoparticles on human neutrophil activation and formation of Neutrophil Extracellular Traps (NETs).
Tsong-Long Hwang
2015
Synthesis and pharmacological characterization of 2-aminobenzaldehyde oxime analogs as dual inhibitors of neutrophil elastase and proteinase 3.
Tsong-Long Hwang
2015
Briarenolides K and L, new anti-inflammatory briarane diterpenoids from an octocoral Briareum sp. (Briareidae).
Tsong-Long Hwang
2015
Cationic additives in nanosystems activate cytotoxicity and inflammatory response of human neutrophils: Lipid nanoparticles versus polymeric nanoparticles.
Tsong-Long Hwang
2015
Bioactive 6S-styryllactone constituents of Polyalthia parviflora.
Tsong-Long Hwang
2014
Rumphellaoic acid A, a novel sesquiterpenoid from the formosan gorgonian coral Rumphella antipathies.
Tsong-Long Hwang
2014
Briarenolide J, the first 12-chlorobriarane diterpenoid from an octocoral Briareum sp. (Briareidae).
Tsong-Long Hwang
2014
Rumphellaones B and C, new 4,5-seco-caryophyllane sesquiterpenoids from Rumphella antipathies.
Tsong-Long Hwang
2014
New briarane diterpenoids from Taiwanese soft coral Briareum violacea.
Tsong-Long Hwang
2014
Rumphellols A and B, new caryophyllene sesquiterpenoids from a formosan gorgonian coral, Rumphella antipathies.
Tsong-Long Hwang
2014
Krempfielins Q and R, two new eunicellin-based diterpenoids from the soft coral Cladiella krempfi.
Tsong-Long Hwang
2014
Anti-inflammatory spirostanol and furostanol saponins from Solanum macaonense.
Tsong-Long Hwang
2014
Seven new sesquiterpenoids from the fruits of Schisandra sphenanthera.
Tsong-Long Hwang
2014
Two diterpenoids and a cyclopenta[c]pyridine derivative from roots of Salvia digitaloids.
Tsong-Long Hwang
2014
Garcimultiflorone G, a novel benzoylphloroglucinol derivative from Garcinia multiflora with inhibitory activity on neutrophil pro‐inflammatory responses.
Tsong-Long Hwang
2014
Eunicellin-based diterpenoids, hirsutalins N-R, from the formosan soft coral Cladiella hirsute.
Tsong-Long Hwang
2014
New coumarins and anti-inflammatory constituents from the fruits of Cnidium monnieri.
Tsong-Long Hwang
2014
Constituents of the roots of Clausena lansium and their potential anti-inflammatory activity.
Tsong-Long Hwang
2014
A novel immunomodulatory effect of ugonin U in human neutrophils via stimulation of phospholipase C.
Tsong-Long Hwang
2014
Anti-inflammatory triterpenoids from the stems of microtropis fokienensis.
Tsong-Long Hwang
2014
New cembranoids from the soft coral Sinularia arborea.
Tsong-Long Hwang
2014
Intracellular glutathione depletion by oridonin leads to apoptosis in hepatic stellate cells.
Tsong-Long Hwang
2014
Tortuosenes A and B, new diterpenoid metabolites from the Formosan soft coral Sarcophyton tortuosum.
Tsong-Long Hwang
2014
Cationic surfactants in the form of nanoparticles and micelles elicit different human neutrophil responses: A toxicological study.
Tsong-Long Hwang
2014
Krempfielins N-P, new anti-inflammatory eunicellins from a taiwanese soft coral Cladiella krempfi.
Tsong-Long Hwang
2014
2014
Synthesis and structural characterization of an anti-inflammatory principle purified from Lindera aggregate.
Tsong-Long Hwang
2014
2014
In vitro anti-inflammatory effects of diterpenoids and sesquiterpenoids from traditional Chinese medicine Siegesbeckia pubescens.
Tsong-Long Hwang
2014
1,5-Diphenylpent-3-en-1-ynes and methyl naphthalene carboxylates from Lawsonia inermis and their anti-inflammatory activity.
Tsong-Long Hwang
2013
Reevesioside F induces potent and efficient anti-proliferative and apoptotic activities through Na+/K+-ATPase α3 subunit-involved mitochondrial stress and amplification of caspase cascades.
Tsong-Long Hwang
2013
Biphenyl-type neolignans from Magnolia officinalis and their anti-inflammatory activities.
Tsong-Long Hwang
2013
Anti-neutrophilic inflammatory steroidal glycosides from Solanum torvum.
Tsong-Long Hwang
2013
2013
Triterpenoids and steroids from Ganoderma mastoporum and their inhibitory effects on superoxide anion generation and elastase release.
Tsong-Long Hwang
2013
Four new briarane diterpenoids from Taiwanese gorgonian Junceella fragilis.
Tsong-Long Hwang
2013
Non-invasive synergistic treatment of brain tumors by targeted chemotherapeutic delivery and amplified focused ultrasound-hyperthermia using magnetic nanographene oxide.
Tsong-Long Hwang
2013
Three novel sesquiterpenes from the mycelium of Phellinus linteus.
Tsong-Long Hwang
2013
Natural clovanes from the gorgonian coral Rumphella antipathies.
Tsong-Long Hwang
2013
New Labdane-type diterpenoids and anti-inflammatory constituents from Hedychium coronarium.
Tsong-Long Hwang
2013
Flexibilins A-C, new cembrane-type diterpenoids from the formosan soft coral, Sinularia flexibilis.
Tsong-Long Hwang
2013
Two anti-inflammatory steroidal saponins from Dracaena angustifolia Roxb.
Tsong-Long Hwang
2013
Krempfielins J-M, new eunicellin-based diterpenoids from the soft coral Cladiella krempfi.
Tsong-Long Hwang
2013
Bioactive secondary metabolites of a marine Bacillus sp. inhibit superoxide generation and elastase release in human neutrophils by blocking formyl peptide receptor 1.
Tsong-Long Hwang
2013
Eunicellin-based diterpenoids from the Formosan soft coral Klyxum molle with inhibitory activity on superoxide generation and elastase release by neutrophils.
Tsong-Long Hwang
2013
Propofol inhibits superoxide production, elastase release and chemotaxis in formyl peptide-activated human neutrophils by blocking formyl peptide receptor 1.
Tsong-Long Hwang
2013
New Benzo[c]phenanthridine and benzenoid derivatives and other constituents from Zanthoxylum ailanthoides: Effects on neutrophil pro-inflammatory responses.
Tsong-Long Hwang
2013
An epigenetic modifier enhances the production of anti-diabetic and anti-inflammatory sesquiterpenoids from Aspergillus sydowii.
Tsong-Long Hwang
2013
Design and synthesis of tryptophan containing dipeptide derivatives as formyl peptide receptor 1 antagonist.
Tsong-Long Hwang
2013
2013
A new hydroxychavicol dimer from the roots of Piper betle.
Tsong-Long Hwang
2013
Hepatitis B virus X protein disrupts stress fiber formation and triggers apoptosis.
Tsong-Long Hwang
2013
Rumphellclovanes C-E, new clovane-type sesquiterpenoids from the gorgonian coral Rumphella antipathies.
Tsong-Long Hwang
2013
Maximizing dermal targeting and minimizing transdermal penetration by magnolol/honokiol methoxylation.
Tsong-Long Hwang
2013
Isolation and synthesis of melodamide a, a new anti-inflammatory phenolic amide from the leaves of Melodorum fruticosum.
Tsong-Long Hwang
2013
Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor, induces the production of anti-inflammatory cyclodepsipeptides from Beauveria felina.
Tsong-Long Hwang
2013
New approach to the characterization and quantification of antrodia cinnamomea benzenoid components utilizing hplc-pda, qnmr and hplc-tandem ms: comparing the wild fruiting bodies and its artificial cultivated commercial products.
Tsong-Long Hwang
2013
Potent inhibition of human neutrophil activations by bractelactone, a novel chalcone from Fissistigma bracteolatum.
Tsong-Long Hwang
2013
Indigo naturalis upregulates claudin-1 expression in human keratinocytes and psoriatic lesions.
Tsong-Long Hwang
2013
Design and synthesis of gambogic acid analogs as potent cytotoxic and anti-inflammatory agents.
Tsong-Long Hwang
2012
New briarane diterpenoids from the gorgonian coral Junceella juncea.
Tsong-Long Hwang
2012
Chemical constituents from Farfugium japonicum var. formosanum.
Tsong-Long Hwang
2012
Cladieunicellin H, a new hemiketal eunicellin-based diterpenoid from the octocoral Cladiella sp.
Tsong-Long Hwang
2012
Bioactive compounds from a gorgonian coral Echinomuricea sp. (Plexauridae).
Tsong-Long Hwang
2012
Briarenolides F and G, new briarane diterpenoids from a Briareum sp. octocoral.
Tsong-Long Hwang
2012
Indiosides G-K: Steroidal Glycosides with Cytotoxic and anti-inflammatory activities from Solanum violaceum.
Tsong-Long Hwang
2012
2012
Anti-neutrophilic inflammatory secondary metabolites from the traditional Chinese medicine, Tiankuizi.
Tsong-Long Hwang
2012
Bioactive isocoumarins from Cissus pteroclada.
Tsong-Long Hwang
2012
YC-1 potentiates cAMP-induced CREB activation and nitric oxide production in alveolar macrophages.
Tsong-Long Hwang
2012
Anti-inflammatory activity and percutaneous absorption of quercetin and its polymethoxylated compound and glycosides: The relationships to chemical structures.
Tsong-Long Hwang
2012
New coumarins and anti-inflammatory constituents from Zanthoxylum avicennae.
Tsong-Long Hwang
2012
Bioactive constituents of Clausena lansium and a method for discrimination of aldose enantiomers.
Tsong-Long Hwang
2012
Orthoquinone and naphthalenone derivatives from Berrya ammonilla and their anti-inflammatory activity.
Tsong-Long Hwang
2012
Echinohalimane A, a bioactive halimane-type diterpenoid from a Formosan Gorgonian Echinomuricea sp. (Plexauridae).
Tsong-Long Hwang
2012
Briarenolides H and I: New 8-hydroxybriarane diterpenoids from a formosan octocoral Briareum sp. (Briareidae).
Tsong-Long Hwang
2012
Echinoclerodane A: A new bioactive clerodane-type diterpenoid from a gorgonian coral Echinomuricea sp.
Tsong-Long Hwang
2012
Briarenolide E: The first 2-ketobriarane diterpenoid from an octocoral Briareum sp. (Briareidae).
Tsong-Long Hwang
2012
Constituents from Vigna vexillata and their anti-inflammatory activity.
Tsong-Long Hwang
2012
Tropisetron attenuates cardiac injury in a rat trauma-hemorrhage model.
Tsong-Long Hwang
2012
Pseudoalteromone B: a novel 15C compound from a marine bacterium Pseudoalteromonas sp. CGH2XX.
Tsong-Long Hwang
2012
Pseudoalteromone A: A novel bioactive ubiquinone from a marine bacterium Pseudoalteromonas sp. CGH2XX (Pseudoalteromonadaceae).
Tsong-Long Hwang
2012
2012
2012
Terpenoids from the octocorals Menella sp. (plexauridae) and Lobophytum crassum (alcyonacea).
Tsong-Long Hwang
2012
A new benzoylphloroglucinol derivative with an adamantyl skeleton and other constituents from Garcinia multiflora: Effects on neutrophil pro‐inflammatory responses.
Tsong-Long Hwang
2012
2012
New bichalcone analogs as NF-κB inhibitors and as cytotoxic agents inducing Fas/CD95-dependent apoptosis.
Tsong-Long Hwang
2011
Cladieunicellins AE, new eunicellins from an Indonesian soft coral Cladiella sp.
Tsong-Long Hwang
2011
Synthesis, in vitro anti-inflammatory and cytotoxic evaluation, and mechanism of action studies of 1-benzoyl-β-carboline and 1-benzoyl-3-carboxy-β-carboline derivatives.
Tsong-Long Hwang
2011
Anti-inflammatory and antioxidant components from Hygroryza aristata.
Tsong-Long Hwang
2011
Rumphellclovane B, a novel clovane analogue from the gorgonian coral Rumphella antipathies.
Tsong-Long Hwang
2011
Anti-inflammatory, anticholinesterase and antioxidative constituents from the roots and the leaves of Salvia nipponica Miq. var. formosana.
Tsong-Long Hwang
2011
First total synthesis of antrocamphin A and its analogs as anti-inflammatory and anti-platelet aggregation agents.
Tsong-Long Hwang
2011
Superhigh-magnetization nanocarrier as a doxorubicin delivery platform for magnetic targeting therapy.
Tsong-Long Hwang
2011
YC-1 inhibits lipid droplet accumulation and induces lipolysis in lipid-laden RAW264.7 macrophages.
Tsong-Long Hwang
2011
Anthranilic acid-based inhibitors of phosphodiesterase: Design, synthesis and bioactive evaluation.
Tsong-Long Hwang
2011
Vitisin B, a resveratrol tetramer, inhibits migration through inhibition of PDGF signaling and enhancement of cell adhesiveness in cultured vascular smooth muscle cells.
Tsong-Long Hwang
2011
Viscolin reduces VCAM-1 expression in TNF-α-treated endothelial cells via the JNK/NF-κB and ROS pathway.
Tsong-Long Hwang
2011
2011
Discovery of novel sesquiterpenoids from a gorgonian Menella sp.
Tsong-Long Hwang
2011
Bioactive components from the heartwood of Pterocarpus santalinus.
Tsong-Long Hwang
2011
A new ferulic acid ester, a new ellagic acid derivative and other constituents from Pachycentria formosana: Effects on neutrophil pro-inflammatory responses.
Tsong-Long Hwang
2011
EMR2 receptor ligation modulates cytokine secretion profiles and cell survival of lipopolysaccharide-treated neutrophils.
Tsong-Long Hwang
2011
Frajunolides L-O, four new 8-hydroxybriarane diterpenoids from the Gorgonian Junceella fragilis.
Tsong-Long Hwang
2011
Menelloides C and D, new sesquiterpenoids from the Gorgonian coral Menella sp.
Tsong-Long Hwang
2011
Lobocrassins A-E: New cembrane-type diterpenoids from the soft coral Lobophytum crassum.
Tsong-Long Hwang
2011
(-)-hydroxylindestrenolide, a new sesquiterpenoid from a gorgonian coral Menella sp. (Plexauridae).
Tsong-Long Hwang
2011
2-(2-Fluorobenzamido)benzoate ethyl ester (EFB-1) inhibits superoxide production by human neutrophils and attenuates hemorrhagic shock-induced organ dysfunction in rats.
Tsong-Long Hwang
2011
Activated human neutrophil response to perfluorocarbon nanobubbles: Oxygen-dependent and -independent cytotoxic responses.
Tsong-Long Hwang
2011
Discovery of new eunicellins from an Indonesian octocoral Cladiella sp.
Tsong-Long Hwang
2011
Partially purified extract and viscolin from Viscum coloratum attenuate airway inflammation and eosinophil infiltration in ovalbumin-sensitized mice.
Tsong-Long Hwang
2011
Thymol, benzofuranoid and phenylpropanoid derivatives: Anti-inflammatory constituents from Eupatorium cannabinum.
Tsong-Long Hwang
2011
Anti-inflammatory and cytotoxic neoflavonoids and benzofurans from Pterocarpus santalinus.
Tsong-Long Hwang
2011
Cladielloides C and D: Novel eunicellin-based diterpenoids from an Indonesian octocoral Cladiella sp.
Tsong-Long Hwang
2011
Role of estrogen receptor-dependent upregulation of P38 MAPK/heme oxygenase 1 in resveratrol-mediated attenuation of intestinal injury after trauma-hemorrhage.
Tsong-Long Hwang
2011
Chemical constituents from Lobelia chinensis and their anti-virus and anti-inflammatory bioactivities.
Tsong-Long Hwang
2011
Costunolide induces apoptosis through nuclear Calcium2+ overload and DNA damage response in human prostate cancer.
Tsong-Long Hwang
2011
Bioactive constituents from the roots of Panax japonicus var. major and development of a LC-MS/MS method for distinguishing between natural and artifactual compounds.
Tsong-Long Hwang
2011
Inhibitory effects of Mannich bases of heterocyclic chalcones on NO production by activated RAW 264.7 macrophages and superoxide anion generation and elastase release by activated human neutrophils.
Tsong-Long Hwang
2011
New benzenoids and anti-inflammatory constituents from Zanthoxylum nitidum.
Tsong-Long Hwang
2011
A novel alkaloid, aristopyridinone A and anti-inflammatory phenanthrenes isolated from Aristolochia manshuriensis.
Tsong-Long Hwang
2011
Antitumor agents. 271: Total synthesis and evaluation of brazilein and analogs as anti-inflammatory and cytotoxic agents.
Tsong-Long Hwang
2010
Resveratrol prevents endothelial dysfunction and aortic superoxide production after trauma hemorrhage through estrogen receptor-dependent hemeoxygenase-1 pathway.
Tsong-Long Hwang
2010
Role of Akt-dependent up-regulation of hemeoxygenase-1 in resveratrol-mediated attenuation of hepatic injury after trauma-hemorrhage.
Tsong-Long Hwang
2010
Acetogenin and prenylated flavonoids from Helminthostachys zeylanica with inhibitory activity on superoxide generation and elastase release by Neutrophils.
Tsong-Long Hwang
2010
Synthesis and evaluation of benzoxazinone derivatives on activity of human neutrophil elastase and on hemorrhagic shock-induced lung injury in rats.
Tsong-Long Hwang
2010
The hederagenin saponin SMG-1 is a natural FMLP receptor inhibitor that suppresses human neutrophil activation.
Tsong-Long Hwang
2010
Excavatoids L-N, new 12-hydroxybriaranes from the cultured octocoral Briareum excavatum (Briareidae).
Tsong-Long Hwang
2010
Carijoside A, a bioactive sterol glycoside from an octocoral Carijoa sp. (Clavulariidae).
Tsong-Long Hwang
2010
Ixorapeptide I and ixorapeptide II, bioactive peptides isolated from Ixora coccinea.
Tsong-Long Hwang
2010
Cladielloides A and B: New eunicellin-type diterpenoids from an Indonesian octocoral Cladiella sp.
Tsong-Long Hwang
2010
Briaviodiol A, a new cembranoid from a soft coral Briareum violacea.
Tsong-Long Hwang
2010
Excavatoids O and P, new 12-hydroxybriaranes from the octocoral Briareum excavatum.
Tsong-Long Hwang
2010
Salviatalin A and salvitrijudin A, two diterpenes with novel skeletons from roots of Salvia digitaloides and anti-inflammatory evaluation.
Tsong-Long Hwang
2010
Nortriterpene lactones from the fruits of Schisandra arisanensis.
Tsong-Long Hwang
2010
Chlorinated briarane diterpenoids from the sea whip gorgonian corals Junceella fragilis and Ellisella robusta (Ellisellidae).
Tsong-Long Hwang
2010
A new quinolone and other constituents from the fruits of Tetradium ruticarpum: Effects on neutrophil pro‐inflammatory responses.
Tsong-Long Hwang
2010
Excavatoids GK, new 8, 17-epoxybriaranes from the cultured octocoral Briareum excavatum (Briareidae).
Tsong-Long Hwang
2010
Rumphellclovane A, a novel clovane-related sesquiterpenoid from the gorgonian coral Rumphella antipathies.
Tsong-Long Hwang
2010
Sesquiterpenes from the rhizome of Curcuma longa with inhibitory activity on superoxide generation and elastase release by neutrophils.
Tsong-Long Hwang
2010
Fragilide G, a new briarane-type diterpenoid from the gorgonian coral Ellisella robusta.
Tsong-Long Hwang
2010
Rumphellolide H, a new natural caryophyllane from the Gorgonian Rumphella antipathies.
Tsong-Long Hwang
2009
Development and evaluation of perfluorocarbon nanobubbles for apomorphine delivery.
Tsong-Long Hwang
2009
Potent inhibition of superoxide anion production in activated human neutrophils by isopedicin, a bioactive component of the Chinese medicinal herb Fissistigma oldhamii.
Tsong-Long Hwang
2009
Suppression of superoxide anion and elastase release by C18 unsaturated fatty acids in human neutrophils.
Tsong-Long Hwang
2009
Anti-inflammatory Flavonoids from the Rhizomes of Helminthostachys zeylanica.
Tsong-Long Hwang
2009
Anti-inflammatory effects of the extract of indigo naturalis in human neutrophils.
Tsong-Long Hwang
2009
DSM-RX78, a new phosphodiesterase inhibitor, suppresses superoxide anion production in activated human neutrophils and attenuates hemorrhagic shock-induced lung injury in rats.
Tsong-Long Hwang
2009
Permeation enhancer-containing water-in-oil nanoemulsions as carriers for intravesical cisplatin delivery.
Tsong-Long Hwang
2009
Excavatoids E and F: discovery of two new briaranes from the cultured octocoral Briareum excavatum.
Tsong-Long Hwang
2009
Asterolaurins A-F, xenicane diterpenoids from the Taiwanese soft coral Asterospicularia laurae.
Tsong-Long Hwang
2009
Acasiane A and B and Farnesirane A and B, Diterpene derivatives from the roots of Acacia farnesiana.
Tsong-Long Hwang
2009
Rumphellolide I, a novel caryophyllane-related tetrahydropyran norsesquiterpenoid from gorgonian coral Rumphella antipathies.
Tsong-Long Hwang
2009
Amides and benzenoids from Zanthoxylum ailanthoides with inhibitory activity on superoxide generation and elastase release by neutrophils.
Tsong-Long Hwang
2009
Benzophenone Derivatives from the Fruits of Garcinia multiflora and their anti-inflammatory activity.
Tsong-Long Hwang
2009
Flavonol glycosides from muehlenbeckia platyclada and their anti-inflammatory activity.
Tsong-Long Hwang
2009
Design and synthesis of new N-(fluorenyl-9-methoxycarbonyl) (Fmoc)-dipeptides as anti-inflammatory agents.
Tsong-Long Hwang
2009
Acoustically active perfluorocarbon nanoemulsions as drug delivery carriers for camptothecin: Drug release and cytotoxicity against cancer cells.
Tsong-Long Hwang
2009
Curcuphenol derivatives from the gorgonian Echinomuricea sp.
Tsong-Long Hwang
2009
Briaexcavatins VZ, discovery of new briaranes from a cultured octocoral Briareum excavatum.
Tsong-Long Hwang
2009
Evaluation of the bioactivities of extracts of endophytes isolated from Taiwanese herbal plants.
Tsong-Long Hwang
2009
YC-1 attenuates homotypic human neutrophil aggregation through inhibition of phosphodiesterase activity.
Tsong-Long Hwang
2008
TNFα enhances neutrophil adhesiveness: Induction of VCAM-1 via activation of Akt and CaM kinase II and modification of HAT and HDAC4 in human tracheal smooth muscle cells.
Tsong-Long Hwang
2008
Anthraquinones from Polygonum cuspidatum as tyrosinase inhibitors for dermal use.
Tsong-Long Hwang
2008
Briaexcavatins M-P, four new briarane-related diterpenoids from cultured octocoral Briareum excavatum (Briareidae).
Tsong-Long Hwang
2008
(-)-Xanthienopyran, a new inhibitor of superoxide anion generation by activated neutrophils and further constituents of the seeds of Xanthium strumarium.
Tsong-Long Hwang
2008
A new indole alkaloid and anti-inflammatory constituents from Strychnos cathayensis.
Tsong-Long Hwang
2008
Junceols D-H, new polyoxygenated briaranes from sea whip gorgonian coral Junceella juncea (Ellisellidae).
Tsong-Long Hwang
2008
Frajunolides E-K, briarane diterpenes from Junceella fragilis.
Tsong-Long Hwang
2008
Phthalides from Pittosporum illicioides var. illicioides with inhibitory activity on superoxide generation and elastase release by neutrophils.
Tsong-Long Hwang
2008
New polyoxygenated briaranes from octocorals Briareum excavatum and Ellisella robusta.
Tsong-Long Hwang
2008
Inhibitory effects of 16-hydroxycleroda-3, 13 (14) E-dien-15-oic acid on superoxide anion and elastase release in human neutrophils through multiple mechanisms.
Tsong-Long Hwang
2008
Rumphellatin D, a Novel Caryophyllane from Gorgonian Coral Rumphella antipathies.
Tsong-Long Hwang
2008
Benzoic acid derivatives, acetophenones and anti-inflammatory constituents from Melicope semecarpifolia.
Tsong-Long Hwang
2008
Neolignans, a coumarinolignan, lignan derivatives and a chromene: Anti-inflammatory constituents from Zanthoxylum avicennae.
Tsong-Long Hwang
2008
New briaranes from the octocorals Briareum excavatum (Briareidae) and Junceella fragilis (Ellisellidae).
Tsong-Long Hwang
2008
New 8-hydroxybriarane diterpenoids from the gorgonians Junceella juncea and Junceella fragilis (Ellisellidae).
Tsong-Long Hwang
2008
Eupatozansins A-C, sesquiterpene lactones from Eupatorium chinense var. tozanense.
Tsong-Long Hwang
2008
Relationship between unstimulated salivary flow rate and saliva composition of healthy children in Taiwan.
Tsong-Long Hwang
2008
Fragilide B: A Novel Briarane-Type Diterpenoid with a S-cis Diene Moiety.
Tsong-Long Hwang
2007
Briaexcavatins G and H, two new briaranes from the octocoral Briareum excavatum.
Tsong-Long Hwang
2007
The evaluation and structure-activity relationships of 2-benzoylaminobenzoic esters and their analogues as anti-inflammatory and anti-platelet aggregation agents.
Tsong-Long Hwang
2007
Cisplatin encapsulated in phosphatidylethanolamine liposomes enhances the in vitro cytotoxicity and in vivo intratumor drug accumulation against melanomas.
Tsong-Long Hwang
2007
2007
Four new briarane diterpenoids from the gorgonian coral Junceella fragilis.
Tsong-Long Hwang
2007
Chemical transformation and biological activities of ambrein, a major product of ambergris from Physeter macrocephalus (Sperm Whale).
Tsong-Long Hwang
2007
The inhibition of superoxide anion generation in human neutrophils by Viscum coloratum.
Tsong-Long Hwang
2006
Anti-inflammatory and cytotoxic diterpenes from formosan Polyalthia longifolia var. pendula.
Tsong-Long Hwang
2006
Briaexcavatins C-F, four new briarane-related diterpenoids from the Formosan octocoral Briareum excavatum (Briareidae).
Tsong-Long Hwang
2006
Briaexcavatins G and H, two new briaranes from the octocoral Briareum excavatum.
Tsong-Long Hwang
2006
Viscolin, a new chalcone from Viscum coloratum, inhibits human neutrophil superoxide anion and elastase release via a cAMP-dependent pathway.
Tsong-Long Hwang
2006
The inhibition of superoxide anion generation in human neutrophils by Viscum coloratum.
Tsong-Long Hwang
2006
Inhibition of superoxide anion and elastase release in human neutrophils by 3'-isopropoxychalcone via a cAMP‐dependent pathway.
Tsong-Long Hwang
2006
Enhancement of the transdermal delivery of catechins by liposomes incorporating anionic surfactants and ethanol.
Tsong-Long Hwang
2006
Liposomes as vehicles for enhancing drug delivery via skin routes.
Tsong-Long Hwang
2006
Junceellolides JL, 11, 20-epoxybriaranes from the gorgonian coral Junceella fragilis.
Tsong-Long Hwang
2006
BK-induced cytosolic phospholipase A2 expression via sequential PKC‐δ, p42/p44 MAPK and NF‐κB activation in rat brain astrocytes.
Tsong-Long Hwang
2006
Physicochemical characterization and gene transfection efficiency of lipid emulsions with various co-emulsifiers.
Tsong-Long Hwang
2005
Suppression of respiratory burst in human neutrophils by new synthetic pyrrolo-benzylisoquinolines.
Tsong-Long Hwang
2005
Transdermal delivery of tea catechins by electrically assisted methods.
Tsong-Long Hwang
2005
Selective cytotoxicity of azatyrosinamides against ras-transformed NIH 3T3 cells.
Tsong-Long Hwang
2005
An anti-inflammatory ent-kaurane from the stems of Annona squamosa that inhibits various human neutrophil functions.
Tsong-Long Hwang
2005
The evaluation of 2, 8-disubstituted benzoxazinone derivatives as anti-inflammatory and anti-platelet aggregation agents.
Tsong-Long Hwang
2005
Potential Anti‐Inflammatory Activities of Bractelactone and other Compounds Isolated from Fissistigma bracteolatum.
Tsong-Long Hwang
2005
Anti-inflammatory furanogermacrane sesquiterpenes from Neolitsea parvigemma.
Tsong-Long Hwang
2005
Physicochemical characteristics and in vivo deposition of liposome-encapsulated tea catechins by topical and intratumor administrations.
Tsong-Long Hwang
2005
Essential oils from sweet basil (Ocimum basilicum) as novel enhancers to accelerate transdermal drug delivery.
Tsong-Long Hwang
2004
A new anti-HIV alkaloid, drymaritin and a new C-glycoside flavonoid, diandraflavone, from Drymaria diandra.
Tsong-Long Hwang
2004
The inhibition of superoxide anion generation by neutrophils from Viscum articulactum.
Tsong-Long Hwang
2004
Inhibitory effects of ent-kauranes from the stems of Annona squamosa on superoxide anion generation by human neutrophils.
Tsong-Long Hwang
2004
Soluble guanylyl cyclase activator YC-1 inhibits human neutrophil functions through a cGMP-independent but cAMP-dependent pathway.
Tsong-Long Hwang
2003
The role of PAR4 in thrombin-induced thromboxane production in human platelets.
Tsong-Long Hwang
2003
Potentiation of tumor necrosis factor-α expression by YC-1 in alveolar macrophages through a cyclic GMP-independent pathway.
Tsong-Long Hwang
2003
Effect of active synthetic 2-substituted quinazolinones on anti-platelet aggregation and the inhibition of superoxide anion generation by neutrophils.
Tsong-Long Hwang
2003
Development of sesquiterpenes from Alpinia oxyphylla as novel skin permeation enhancers.
Tsong-Long Hwang
2003
In vitro and in vivo evaluations of the efficacy and safety of skin permeation enhancers using flurbiprofen as a model drug.
Tsong-Long Hwang
2003
Effect of enhancers and retarders on percutaneous absorption of flurbiprofen from hydrogels.
Tsong-Long Hwang
2003
The nonadrenergic noncholinergic system can modulate the effect of prokinetic agents on contractile response of isolated guinea-pig trachea segments to electrical field stimulation.
Tsong-Long Hwang
2002
Transdermal iontophoresis of sodium nonivamide acetate: V. Combined effect of physical enhancement methods.
Tsong-Long Hwang
2002
Selective inhibition of protease-activated receptor 4-dependent platelet activation by YD-3.
Tsong-Long Hwang
2002
Broussochalcone a, a potent antioxidant and effective suppressor of inducible nitric oxide synthase in lipopolysaccharide-activated macrophages.
Tsong-Long Hwang
2001
Inhibition of the expression of inducible nitric oxide synthase and cyclooxygenase-2 in macrophages by 7HQ derivatives: Involvement of IkappaB-α stabilization.
Tsong-Long Hwang
2001
Inhibitory effect of DCDC on lipopolysaccharide-induced nitric oxide synthesis in RAW 264.7 cells.
Tsong-Long Hwang
2001
The mechanism of actions of 3-(5'-(hydroxymethyl-2'-furyl)-1-benzyl indazole (YC-1) on Ca2+-activated K+ currents in GH3 lactotrophs.
Tsong-Long Hwang
2000
YD-3, a novel inhibitor of protease-induced platelet activation.
Tsong-Long Hwang
2000
Pharmacological characterization of EK112, a new combined angiotensin II and thromboxane A2 receptor antagonist.
Tsong-Long Hwang
2000
YC-1 potentiates nitric oxide-induced relaxation in guinea-pig trachea.
Tsong-Long Hwang
1999
Comparison of two soluble guanylyl cyclase inhibitors, methylene blue and ODQ, on sodium nitroprusside-induced relaxation in guinea-pig trachea.
Tsong-Long Hwang
1998
Cell proliferation in human prostatic smooth muscle cells involves the modulation of protein kinase C isozymes.
Tsong-Long Hwang
1998
Antiproliferative effect in human prostatic smooth muscle cells by nitric oxide donor.
Tsong-Long Hwang
1998
Activation of muscarinic K+ channels by extracellular ATP and UTP in rat atrial myocytes.
Tsong-Long Hwang
1998
Ionic mechanisms of tetrandrine in cultured rat aortic smooth muscle cells.
Tsong-Long Hwang
1997
Analysis of mechanical restitution and post-rest potentiation in isolated rat atrium.
Tsong-Long Hwang
1996
Vaninolol: A new selective β1-adrenoceptor antagonist derived from vanillin.
Tsong-Long Hwang
1994