About
Professional Summary
Dr. Mark George Rae is currently holds a position of Principal Investigator and Lecturer at Department of Physiology, University College Cork, Ireland. He has completed his Ph.D. in Pharmacology from University of Glasgow, UK. Previously he was appointed as Post-Doctoral Fellow at University of Strathclyde, and Department Physiology & Pharmacology, University of Nevada, University of Aberdeen, and Senior Post-Doctoral Fellow at University of Dundee, Research Electrophysiologist at Ionix Pharmaceuticals Ltd., Cambridge, Senior Research Fellow at Molecular Nociception Group, University College London, Senior Research Fellow at Astellas CNS in Edinburgh (ACE), Edinburgh University and Laboratory Coordinator at Department of Physiology, University College Cork. He is, or has been, an active member of several professional bodies in his career, presenting at numerous conferences as a member of the following professional bodies: The Physiological Society, Neuroscience Ireland, The Biochemical Society, International Society to Advance Alzheimer’s Research & Treatment, The British Neuroscience Association, Society for Neuroscience, The British Pharmacological Society, American Gastrointestinal Association, Scottish Neuroscience Group and American Gastrointestinal Association. He has acted as an expert reviewer for a number of journals including: British Journal of Pharmacology, The Journal of Physiology, The Journal of Endocrinology, Toxicology Letters, Brain Research Bulletin, and Scholarship of Teaching and Learning. He has published 20 research articles in journals contributed as author/co-author. He supervised 2 MSc students thesis and currently supervising 2 PhD and 1 MSc student thesis.
Education
Academic Background
Editorial Services
Editorial & Publishing Roles
Editorial Board Member
Jun 2019 — Present
Serving as Editorial Board Member for Journal of Medical Sciences.
Editorial Board Member
Jun 2019 — Present
Serving as Editorial Board Member for Trends in Medical Research.
Editorial Board Member
Jun 2019 — Present
Serving as Editorial Board Member for Current Research in Neuroscience.
Publications (32)
Selected Scholarly Contributions
Role of Oxidative Stress in the Neural Control of Intra-Renal Hemodynamics in Stroke-Prone Spontaneously Hypertensive Rats
Ahmad Ahmeda, Zakarya Ahmeda, Yehia S. Mohamed, Mark G. Rae
International Journal of Molecular Sciences
| Journal Article
2026
Preclinical medical students’ perceptions of physiology online teaching and online physiology teaching tools
Mohammed H. Abdulla, Sara ALMarabeh, Mark G. Rae
Advances in Physiology Education
| Journal Article
2025
An investigation of preclinical medical students’ preference for summative or formative assessment for physiology learning
Mark G. Rae, Mohammed H. Abdulla
Advances in Physiology Education
| Journal Article
2023
Interleukin-6: A neuro-active cytokine contributing to cognitive impairment in Duchenne muscular dystrophy?
Kimberley A. Stephenson, Mark G. Rae, Dervla O'Malley
Cytokine
| Journal Article
2020
No evidence in support of a prodromal respiratory control signature in the TgF344-AD rat model of Alzheimer’s disease
Eric F. Lucking, Kevin H. Murphy, David P. Burns, Anirudh V. Jaisimha, Kevin J. Barry-Murphy, Pardeep Dhaliwal, Barry Boland, Mark G. Rae, Ken D. O’Halloran
Respiratory Physiology & Neurobiology
| Journal Article
2019
Active peer-mentored learning can improve student understanding of physiological concepts in an undergraduate journal club
Bernard T. Drumm, Mark G. Rae, Sean M. Ward
Advances in Physiology Education
| Journal Article
2019
How much do preclinical medical students utilize the internet to study physiology?
Dervla O’Malley, Denis S. Barry, Mark G. Rae
Advances in Physiology Education
| Journal Article
2019
An efficient and cost-effective method of generating postnatal (P2-5) mouse primary hippocampal neuronal cultures.
Kaar, A., S.J. Morley and M.G. Rae,
J. Neurosci. Methods,
| Journal Article

Mark George Rae
2017
Effect of tempol and tempol plus catalase on intra-renal haemodynamics in spontaneously hypertensive stroke-prone (SHSP) and Wistar rats.
Ahmeda, A.F., M.G. Rae, M.F. Al Otaibi, L.M. Anweigi and E.J. Johns,
J. Physiol. Biochem.,
| Journal Article

Mark George Rae
2017
Do prerecorded lecture VODcasts affect lecture attendance of first-yearpre-clinical graduate entry to medicine students?
Rae, M.G. and D. O’Malley,
Med. Teacher,
| Journal Article

Mark George Rae
2017
The impact of vodcast utilisation upon student learning in the physiology component of a first year graduate to entry medicine module.
Rae, M.G. and M. McCarthy,
J. Scholarship Teach. Learn.,
| Journal Article

Mark George Rae
2017
Cognitive dysfunction in Duchenne muscular dystrophy: A possible role for neuromodulatory immune molecules.
Rae, M.G. and D. O’Malley,
J. Neurophys.,
| Journal Article

Mark George Rae
2016
Metabotropic glutamate receptor-mediated cyclic ADP ribose signalling.
Kaar, A. and M.G. Rae,
Biochem. Soc. Trans.,
| Journal Article

Mark George Rae
2015
Modulation of enteric neurons by interleukin-6 and corticotrophin-releasing factor contributes to visceral hypersensitivity and altered colonic motility in a rat model of irritable bowel syndrome.
Buckley, M.M., K.D. O'Halloran, M.G. Rae, T.G. Dinan and D. O'Malley,
J. Physiol.,
| Journal Article

Mark George Rae
2014
Effect of reactive oxygen species and nitric oxide in the neural control of intrarenal haemodynamics in anaesthetized normotensive rats.
Ahmeda, A.F., M.G. Rae and E.J. Johns,
Acta Physiol.,
| Journal Article

Mark George Rae
2013
Putative TRP channel antagonists, SKF 96365, flufenamic acid and 2-APB, are non-competitive antagonists at recombinant human α1β2γ2 GABA(A) receptors.
Rae, M.G., J. Hilton and J. Sharkey,
Neurochem. Int.,
| Journal Article

Mark George Rae
2012
Effect of clazosentan, a selective endothelin a receptor antagonist and tezosentan, a dual endothelin A/B antagonist, on pulsatile shear stress induced constriction of the iliac in the anaesthetized pig.
Ruane-O'Hora, T., M.G. Rae and F. Markos,
Clin. Exp. Pharmacol. Physiol.,
| Journal Article

Mark George Rae
2011
A question of balance-positive versus negative allosteric modulation of GABA(A) receptor subtypes as a driver of analgesic efficacy in rat models of inflammatory and neuropathic pain.
Munro, G., H.K. Erichsen, M.G. Rae and N.R. Mirza,
Neuropharmacology,
| Journal Article

Mark George Rae
2011
Both mGluR1 and mGluR5 mediate Ca2+ release and inward currents in hippocampal CA1 pyramidal neurons.
Rae, M.G. and A.J. Irving,
Neuropharmacology,
| Journal Article

Mark George Rae
2004
Leptin inhibits rat hippocampal neurons via activation of large conductance calcium-activated K+ channels.
Shanley, L.J., A.J. Irving, M.G. Rae, M.L. Ashford and J. Harvey,
Nat. Neurosci.,
| Journal Article

Mark George Rae
2002
Cannabinoids on the brain.
Irving, A.J., M.G. Rae and A.A. Coutts,
Sci. World J.,
| Journal Article

Mark George Rae
2002
Role of Ca2+ stores in mGlu receptor-mediated supralinear Ca2+ signaling in rat hippocampal neurons.
Rae, M.G., D.J. Martin, G.L. Collingridge and A.J. Irving,
J. Neurosci.,
| Journal Article

Mark George Rae
2000
Functional expression of cell surface cannabinoid CB1 receptors on presynaptic inhibitory terminals in cultured rat hippocampal neurons.
Irving, A.J., A.A. Coutts, J. Harvey, M.G. Rae, K. Mackie, G.S. Bewick and R.G. Pertwee,
Neuroscience,
| Journal Article

Mark George Rae
2000
Modulation of cholinergic neuromuscular transmission by nitric oxide in canine colonic circular smooth muscle.
Rae, M.G., M.A. Khoyi and K.D. Keef,
Am. J. Physiol.,
| Journal Article

Mark George Rae
1998
Basal activation of ATP-sensitive potassium channels in murine colonic smooth muscle cell.
Koh, S.D., K.K. Bradley, M.G. Rae, K.D. Keef, B. Horowitz and K.M. Sanders,
Biophys. J.,
| Journal Article

Mark George Rae
1998
Control of motility patterns in the human colonic circular muscle layer by pacemaker activity.
Rae, M.G., N. Fleming, D.B. McGregor, K.M. Sanders and K.D. Keef,
J. Physiol.,
| Journal Article

Mark George Rae
1998
Characterisation of P2X3-receptors present in neurones of rat dorsal root ganglia.
Rae, M.G., E.G. Rowan and C. Kennedy,
Br. J. Pharmacol.,
| Journal Article

Mark George Rae
1998
Characterization of a P2X-purinoceptor in cultured neurones of the rat dorsal root ganglia.
Robertson, S.J., M.G. Rae, E.G. Rowan and C. Kennedy,
Br. J. Pharmacol.,
| Journal Article

Mark George Rae
1996
Neuronal mediators of inhibitory junction potentials and relaxation in the guinea-pig internal anal sphincter.
Rae, M.G. and T.C. Muir,
J. Physiol.,
| Journal Article

Mark George Rae
1996
Regulation of prostaglandin E2 binding to a murine macrophage cell line, P388D1, by insulin.
Rae, M.G., D. Rotondo and A.K. Dutta-Roy,
Biochim. Biophys. Acta,
| Journal Article

Mark George Rae
1992
Interleukin-1 inhibits PGE2 binding to macrophage-like P388D1 cells by a cyclic AMP-independent process.
Rae, M.G., D. Rotondo, A.S. Milton and A.K. Dutta-Roy,
Biochim. Biophys. Acta,
| Journal Article

Mark George Rae
1992
Stimulation of prostaglandin E2 binding to a murine macrophage cell line (P388D1) by insulin.
Dutta-Roy, A.K., M.G. Rae, A.S. Milton and D. Rotondo,
Biochem. Soc. Trans.,
| Journal Article

Mark George Rae
1991