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Sandra Maria Tavares da Costa Rebelo

Sandra Maria Tavares da Costa Rebelo

LiveDNA ID: 351.10467
42 Publications
0 Editorial Roles
0 Projects

About

Professional Summary

Dr. Sandra Maria Tavares da Costa Rebelo is currently working as Invited Assistant Professor at Health Sciences Department, University of Aveiro, Portugal. She has completed her PhD in Biochemistry and Post Doctorate in Neuroscience from same University. Previously she was appointed as Fellowship for Young Investigators, Research Assistant, and Teaching Assistant at University of Aveiro, Portugal. Dr. Sandra received honors includes AstraZeneca Foundation-Research Support Award, Bilateral prize for research cooperation and Brain awareness week grant. She successfully supervised 10 MSc, and 2 PhD students. She also worked on many research projects as principal investigator and assistant researcher and researcher. She has published 21 research articles in journals as author/co-author.

Education

Academic Background
  • Post Doctoral Fellow University of Aveiro, Portugal Neurosciences | Completed: 2012

Publications (42)

Selected Scholarly Contributions
Multisystem Symptoms in Myotonic Dystrophy Type 1: A Management and Therapeutic Perspective
Dhvani H. Kuntawala, Rui Vitorino, Ana C. Cruz, Filipa Martins, Sandra Rebelo
International Journal of Molecular Sciences | Journal Article
10.3390/ijms26115350
Crossref
2025
Spectroscopic Profile of Metabolome Dynamics During Rat Cortical Neuronal Differentiation
Idália Almeida, Filipa Martins, Brian J. Goodfellow, Alexandra Nunes, Sandra Rebelo
International Journal of Molecular Sciences | Journal Article
10.3390/ijms26168027
Crossref
2025
Quantitative proteome analysis of LAP1-deficient human fibroblasts: A pilot approach for predicting the signaling pathways deregulated in LAP1-associated diseases
Cátia D. Pereira, Guadalupe Espadas, Filipa Martins, Anne T. Bertrand, Laurent Servais, Eduard Sabidó, Philippe Chevalier, Odete A.B. da Cruz e Silva, Sandra Rebelo
Biochemistry and Biophysics Reports | Journal Article
10.1016/j.bbrep.2024.101757
Crossref
2024
LAP1 Interactome Profiling Provides New Insights into LAP1’s Physiological Functions
Cátia D. Pereira, Guadalupe Espadas, Filipa Martins, Anne T. Bertrand, Laurent Servais, Eduard Sabidó, Philippe Chevalier, Odete A. B. da Cruz e Silva, Sandra Rebelo
International Journal of Molecular Sciences | Journal Article
10.3390/ijms252413235
Crossref
2024
Automatic Text-Mining Approach to Identify Molecular Target Candidates Associated with Metabolic Processes for Myotonic Dystrophy Type 1
Dhvani H. Kuntawala, Filipa Martins, Rui Vitorino, Sandra Rebelo
International Journal of Environmental Research and Public Health | Journal Article
10.3390/ijerph20032283
Crossref
2023
Protein Phosphorylation Alterations in Myotonic Dystrophy Type 1: A Systematic Review
Adriana Costa, Ana C. Cruz, Filipa Martins, Sandra Rebelo
International Journal of Molecular Sciences | Journal Article
10.3390/ijms24043091
Crossref
2023
New Insights on Signaling Pathways Deregulated in LAP1-Deficient Cells: A Proteomics Study
Cátia D. Pereira, Guadalupe Espadas, Filipa Martins, Anne T. Bertrand, Laurent Servais, Eduard Sabidó, Odete A. B. da Cruz e Silva, Sandra Rebelo
Cells 2023 | Proceedings Article
10.3390/blsf2023021025
Crossref
2023
Age-Related Fourier-Transform Infrared Spectroscopic Changes in Protein Conformation in an Aging Model of Human Dermal Fibroblasts
Cláudia Martins, Idália Almeida, Sandra Rebelo, Sandra Magalhães, Alexandra Nunes
Spectroscopy Journal | Journal Article
10.3390/spectroscj1010004
Crossref
2023
Nuclear Envelope Alterations in Myotonic Dystrophy Type 1 Patient-Derived Fibroblasts
Diana Viegas, Cátia D. Pereira, Filipa Martins, Tiago Mateus, Odete A. B. da Cruz e Silva, Maria Teresa Herdeiro, Sandra Rebelo
International Journal of Molecular Sciences | Journal Article
10.3390/ijms23010522
Crossref
2022
Outcome measures frequently used to assess muscle strength in patients with myotonic dystrophy type 1: a systematic review
Tiago Mateus, Adriana Costa, Diana Viegas, Alda Marques, Maria Teresa Herdeiro, Sandra Rebelo
Neuromuscular Disorders | Journal Article
10.1016/j.nmd.2021.09.014
Crossref
2022
The Long-Term Culture of Human Fibroblasts Reveals a Spectroscopic Signature of Senescence
Sandra Magalhães, Idália Almeida, Cátia D. Pereira, Sandra Rebelo, Brian J. Goodfellow, Alexandra Nunes
International Journal of Molecular Sciences | Journal Article
10.3390/ijms23105830
Crossref
2022
Different Strategies to Attenuate the Toxic Effects of Zinc Oxide Nanoparticles on Spermatogonia Cells
Mariana Vassal, Cátia D. Pereira, Filipa Martins, Vera L. M. Silva, Artur M. S. Silva, Ana M. R. Senos, Maria Elisabete V. Costa, Maria de Lourdes Pereira, Sandra Rebelo
Nanomaterials | Journal Article
10.3390/nano12203561
Crossref
2022
Metabolic Alterations in Myotonic Dystrophy Type 1 and Their Correlation with Lipin
Tiago Mateus, Filipa Martins, Alexandra Nunes, Maria Teresa Herdeiro, Sandra Rebelo
International Journal of Environmental Research and Public Health | Journal Article
10.3390/ijerph18041794
Crossref
2021
Fourier-Transform Infrared Spectroscopy as a Discriminatory Tool for Myotonic Dystrophy Type 1 Metabolism: A Pilot Study
Tiago Mateus, Idália Almeida, Adriana Costa, Diana Viegas, Sandra Magalhães, Filipa Martins, Maria Teresa Herdeiro, Odete A. B. da Cruz e Silva, Carla Fraga, Ivânia Alves, Alexandra Nunes, Sandra Rebelo
International Journal of Environmental Research and Public Health | Journal Article
10.3390/ijerph18073800
Crossref
2021
Metal Oxide Nanoparticles: Evidence of Adverse Effects on the Male Reproductive System
Mariana Vassal, Sandra Rebelo, Maria de Lourdes Pereira
International Journal of Molecular Sciences | Journal Article
10.3390/ijms22158061
Crossref
2021
FTIR Spectroscopy as a Tool to Study Age-Related Changes in Cardiac and Skeletal Muscle of Female C57BL/6J Mice
Sandra Magalhães, Idália Almeida, Filipa Martins, Fátima Camões, Ana R. Soares, Brian J. Goodfellow, Sandra Rebelo, Alexandra Nunes
Molecules | Journal Article
10.3390/molecules26216410
Crossref
2021
The Impact of Zinc Oxide Nanoparticles on Male (In)Fertility
Ana Rita Pinho, Sandra Rebelo, Maria de Lourdes Pereira
Materials | Journal Article
10.3390/ma13040849
Crossref
2020
Nuclear envelope dysfunction and its contribution to the aging process
Filipa Martins, Jéssica Sousa, Cátia D. Pereira, Odete A. B. da Cruz e Silva, Sandra Rebelo
Aging Cell | Journal Article
10.1111/acel.13143
Crossref
2020
In Vitro Cytotoxicity Effects of Zinc Oxide Nanoparticles on Spermatogonia Cells
Ana Rita Pinho, Filipa Martins, M. Elisabete V. Costa, Ana M. R. Senos, Odete A. B. da Cruz e Silva, Maria de Lourdes Pereira, Sandra Rebelo
Cells | Journal Article
10.3390/cells9051081
Crossref
2020
Nuclear Accumulation of LAP1:TRF2 Complex during DNA Damage Response Uncovers a Novel Role for LAP1
Cátia D. Pereira, Filipa Martins, Mariana Santos, Thorsten Müeller, Odete A. B. da Cruz e Silva, Sandra Rebelo
Cells | Journal Article
10.3390/cells9081804
Crossref
2020
Nuclear envelope dynamics during mammalian spermatogenesis: new insights on male fertility
Cátia D. Pereira, Joana B. Serrano, Filipa Martins, Odete A. B. da Cruz e Silva, Sandra Rebelo
Biological Reviews | Journal Article
10.1111/brv.12498
Crossref
2019
Descriptive Analysis of LAP1 Distribution and That of Associated Proteins throughout Spermatogenesis
Joana Serrano, Filipa Martins, João Sousa, Cátia Pereira, Ans Van Pelt, Sandra Rebelo, Odete Da Cruz e Silva
Membranes | Journal Article
10.3390/membranes7020022
Crossref
2017
BRI2 Processing and Its Neuritogenic Role Are Modulated by Protein Phosphatase 1 Complexing
Filipa Martins, Joana B. Serrano, Thorsten Müller, Odete A.B. da Cruz e Silva, Sandra Rebelo
Journal of Cellular Biochemistry | Journal Article
10.1002/jcb.25925
Crossref
2017
Lamina Associated Polypeptide 1 (LAP1) Interactome and Its Functional Features
Joana Serrano, Odete Da Cruz e Silva, Sandra Rebelo
Membranes | Journal Article
10.3390/membranes6010008
Crossref
2016
A novel role of LAP1 in centrosome positioning near the nuclear envelope during the cell cycle.
Santos, M., P. Costa, F. Martins, E.F. da Cruz e Silva, OA.B. Da cruz e Silva and S. Rebelo,
Mol. Cell. Biochem., | Journal Article
Self Sandra Maria Tavares da Costa Rebelo
2015
Phosphoprotein phosphatase 1 isoforms alpha and gamma respond differently to prodigiosin treatment and present alternative kinase targets in melanoma cells.
Fardilha, M., M. Espona-Fiedler, J. Felgueiras, L. Korrodi-Gregorio, S.L. Esteves, S. Rebelo and R. Perez-Tomas,
J. Biophys. Chem., | Journal Article
Self Sandra Maria Tavares da Costa Rebelo
2014
Identification of a novel human LAP1 isoform that is regulated by protein phosphorylation.
Santos, M., S.C. Domingues, P. Costa, T. Muller, S. Galozzi, K. Marcus and S. Rebelo,
PloS one, | Journal Article
Self Sandra Maria Tavares da Costa Rebelo
2014
RanBP9 modulates AICD localization and transcriptional activity via direct interaction with tip60.
Domingues, S.C., U. Konietzko, A.G. Henriques, S. Rebelo, M. Fardilha, H. Nishitani and E.S.O. da Cruz,
J. Alzheimer's dis., | Journal Article
Self Sandra Maria Tavares da Costa Rebelo
2014
The nuclear envelope protein, LAP1B, is a novel protein phosphatase 1 substrate.
Santos, M., S. Rebelo, P.J. Van Kleeff, C.E. Kim, W.T. Dauer, M. Fardilha and E.S.E. da Cruz,
PloS one, | Journal Article
Self Sandra Maria Tavares da Costa Rebelo
2013
Screening of protein phosphatases in human sperm: characterization of ser/thr phosphatase family.
Fardilha, M., M. Ferreira, S. Pelech, S.I. Vieira, S. Rebelo, M. Sousa, A. Barros, V. Silva, O.A.B. Cruz e Silva and E.F. da Cruz e Silva,
OMICS J. Integr. Biol., | Journal Article
Self Sandra Maria Tavares da Costa Rebelo
2013
Identification of a novel complex AβPP: Fe65: PP1 that regulates AβPP Thr668 phosphorylation levels.
Rebelo, S., S.C. Domingues, M. Santos, M. Fardilha, S.L. Esteves, S.I. Vieira and E.S.O. da Cruz,
J. Alzheimer's dis., | Journal Article
Self Sandra Maria Tavares da Costa Rebelo
2012
Immunolocalization of PPP1C Isoforms in SH-SY5Y cells during the cell cycle.
Santos, M., S. Rebelo, O.A.B. Silva and E.F. Silva,
Microsc. Microanal., | Journal Article
Self Sandra Maria Tavares da Costa Rebelo
2012
Identification of the human testis protein phosphatase 1 interactome.
Fardilha, M., S.L. Esteves, L. Korrodi-Gregorio, A.P. Vintem, S.C. Domingues, S. Rebelo and E.F.D.C. e Silva,
Biochem. Pharmcol., | Journal Article
Self Sandra Maria Tavares da Costa Rebelo
2011
S655 phosphorylation enhances APP secretory traffic.
Vieira, S.I., S. Rebelo, S.C. Domingues, E.F.D.C. e Silva and O.A.D.C. e Silva,
Mol. Cell. Biochem., | Journal Article
Self Sandra Maria Tavares da Costa Rebelo
2009
Enhanced generation of Alzheimer's amyloid-β following chronic exposure to phorbol ester correlates with differential effects on alpha and epsilon isozymes of protein kinase C.
Da Cruz E Silva, O.A., S. Rebelo, S.I. Vieira, S. Gandy, E.F. Da Cruz e Silva and P. Greengard,
J. Neurochem., | Journal Article
10.1111/j.1471-4159.2008.05770.x
Self Sandra Maria Tavares da Costa Rebelo
2009
Monitoring de novo APP synthesis by taking advantage of the reversible effect of cycloheximide.
Rebelo, S., S.I. Vieira, E.F.D.C. e Silva and O.A.D.C. e Silva,
Am. J. Alzheimer's dis. dementias, | Journal Article
Self Sandra Maria Tavares da Costa Rebelo
2009
Tyr687 dependent APP endocytosis and Abeta production.
Rebelo, S., S.I. Vieira, O.D.C. e Silva, H. Esselmann, J. Wiltfang and E.D.C. e Silva,
J. mol. Neurosci., | Journal Article
Self Sandra Maria Tavares da Costa Rebelo
2007
TYR687 phosphorylated alzheimer`s amyloid precursor protein is retained intracellularly and exhibits a decreased turnover rate.
Rebelo S., S.I. Vieira, H. Esselmann, J. Wiltfang, E.F. da Cruz e Silva and O.A.B. da Cruz e Silva,
Neurodegenerative Dis., | Journal Article
Self Sandra Maria Tavares da Costa Rebelo
2007
Isoform specific amyloid β precursor protein metabolism.
Henriques A.G., S.I. Vieira, S. Rebelo, S.C.T.S. Domingues, E.F. da Cruz e Silva and O.A.B. da Cruz e Silva,
J. Alzheimer's Dis., | Journal Article
Self Sandra Maria Tavares da Costa Rebelo
2007
Effect of cell density on the intracellular levels of the Alzheimer's amyloid precursor protein.
Rebelo S., A.G. Henriques, E.F. da Cruz e Silva and O.A.B.da Cruz e Silva,
J. Neurosci. Res., | Journal Article
Self Sandra Maria Tavares da Costa Rebelo
2004
Signal transduction therapeutics: a novel approach in Alzheimer's Disease.
da Cruz e Silva O.A.B., M. Fardilha, A.G. Henriques, S. Rebelo, S. Guerra e Paz and E.F. da Cruz e Silva,
J. Mol. Neurosci., | Journal Article
Self Sandra Maria Tavares da Costa Rebelo
2004
A model system to study intracellular trafficking and processing of the Alzheimer's amyloid precursor protein.
da Cruz e Silva, O.A., S.I. Vieira, S. Rebelo and E.F. da Cruz e Silva,
Neurodegenerative Dis., | Journal Article
Self Sandra Maria Tavares da Costa Rebelo
2004