About
Professional Summary
Dr. Sabry A. El-Naggar is currently working as Associate Professor in Department of Biology at Aljouf University, Saudi Arabia. He is a Faculty member at Zoology Department, Faculty of Science, Tanta University, Egypt. He completed his PhD in 2007 from Tanta University in Physiology (Immunology). His area of work includes Molecular Sciences, Immunology, Cancer Biology and Biomedical Sciences. His major interest in research is augmenting cancer-based vaccination through different approaches that can generate strong effector and memory responses of immune cells, Enhance the anti-tumor efficacy against cancer through active vaccination with ex-vivo dendritic cells pulsed with the target antigens in combination of agonists for the toll-like receptors (TLRs) expressed on dendritic cells, Augmenting T cell activation, survival, and function by cytokines such as IL-12 and TLR agonists in vitro before to use them for adoptive T cell therapy, Understanding the mechanisms underlying the beneficial effects of preconditioning a host with cyclophosphamide to adoptive T cell therapy and active vaccination, Screening the anti-cancer activity of some indigenous plants located in Kingdom of Saudi Arabia. He has published more than 20 articles in international and national peer reviewed journals and an active member in more than 10 professional scientific societies. He is also serving more than 6 journals as editor/reviewer. He is awarded the Incentive (Encouraging) National Award in Biology; Academy of Scientific Research and Technology-Egypt. He is awarded the Excellence and Quality Publishing in Aljouf University for the academic year 2013 and 2014.
Education
Academic Background
Editorial Services
Editorial & Publishing Roles
Editorial Board Member
Aug 2015 — Present
Serving as Editorial Board Member for International Journal of Cancer Research.
Editorial Board Member
Aug 2015 — Present
Serving as Editorial Board Member for Research Journal of Immunology.
Editorial Board Member
Sep 2011 — Present
Serving as Editorial Board Member for Journal of Biological Sciences.
Editorial Board Member
Sep 2011 — Present
Serving as Editorial Board Member for International Journal of Zoological Research.
Editorial Board Member
Sep 2011 — Present
Serving as Editorial Board Member for International Journal of Biological Chemistry.
Publications (27)
Selected Scholarly Contributions
The Antioxidant and Anti‐Inflammatory Impacts of Purple and White Eggplants on Fertility and Expression of Fertility‐Related Genes in Rats Treated With Aluminum Chloride
Amira M. Elmoslemany, Medhat Rehan, Fatmah Ahmed Safhi, Neveen M. Zeima, Marwa Fawzy El-Hassnin, Sabry Ali Elnaggar, Ibtesam S. Almami, Amina Zedan
Journal of Toxicology
| Journal Article
2024
Metformin Causes Hepato-renal Dysfunctions in Obese Male Rats
Sabry Ali El-Naggar, Mona Elwan, Mohamed Abo Elftouh Basyouny, Ehab Othman Elshennawy, Karim Samy El-Said
Brazilian Archives of Biology and Technology
| Journal Article
2021
Enhancing Antitumor Efficacy of Cisplatin Low Dose by EDTA in Ehrlich Ascetic Carcinoma Bearing Mice
Sabry Ali El-Naggar, Karim Samy El-Said, Maysa Mobasher, Mohamed Elbakry
Brazilian Archives of Biology and Technology
| Journal Article
2019
Cardioprotective effect of green tea extract and vitamin E on Cisplatin-induced cardiotoxicity in mice: Toxicological, histological and immunohistochemical studies
Mahrous A. Ibrahim, Gamal A. Bakhaat, Hany G. Tammam, Rasha M. Mohamed, Sabry A. El-Naggar
Biomedicine & Pharmacotherapy
| Journal Article
2019
Comparing the effects of single and metronomic treatment with cyclophosphamide on liver and kidney functions in mice.
El-Naggar, S.A.,
Egypt. J. Exp. Biol. (Zool.),
| Journal Article

Sabry Ali Abdallah El-Naggar
2018
Pretreatment with the micro-alga, spirulina platensis ameliorates cyclophosphamide-induced hematological, liver and kidney toxicities in male mice.
El-Naggar, S., M. Ibrahim, H. El-Tantawi and I. Al-Sharkawi,
Ain Shams J. Forensic Med. Clin. Toxicol.,
| Journal Article

Sabry Ali Abdallah El-Naggar
2018
Higher activities of hepatic versus splenic CD8+ T cells in responses to adoptive T cell therapy and vaccination of B6 mice with MHC class-1 binding antigen.
Salem, M.L., R.E. El Naggar, S.A. El Naggar, M.A. Mobasher, M.H. Mahmoud and G. Badr,
Iran. J. Allergy Asthma Immunol.,
| Journal Article

Sabry Ali Abdallah El-Naggar
2017
Metabolomic profiling and antioxidant activity of Opophytum Forsskalii.
Elgebaly, H.A., I.B. Abdel-Farid, U.A. Mahalel, M. Jahangir and S.A. El-Naggar,
Aljouf Sci. Eng. J.,
| Journal Article

Sabry Ali Abdallah El-Naggar
2016
Protective role of Commiphora molmol extract against liver and kidney toxicity induced by carbon tetrachloride in mice.
Alm-Eldeen, A.A., S.A. El-Naggar, K.F. El-Boray, H.A. Elgebaly and I.H. Osman,
Trop. J. Pharmaceut. Res.,
| Journal Article

Sabry Ali Abdallah El-Naggar
2016
Efficacy of Rosmarinus officinalis leaves extract against cyclophosphamide-induced hepatotoxicity.
El-Naggar, S.A., I.B. Abdel-Farid, M.O. Germoush, H.A. Elgebaly and A.A. Alm-Eldeen,
Pharmaceut. Biol.,
| Journal Article

Sabry Ali Abdallah El-Naggar
2016
Metabolomic profiling, antioxidant capacity and in vitro anticancer activity of some compositae plants growing in Saudi Arabia.
El-Naggar, S.A., I.B. Abdel-Farid, H.A. Elgebaly and M.O. Germoush,
Afr. J. Pharm. Pharmacol.,
| Journal Article

Sabry Ali Abdallah El-Naggar
2015
Ameliorative effect of propolis against cyclophosphamide-induced toxicity in mice.
El-Naggar, S.A., A.A. Alm-Eldeen, M.O. Germoush, K.F. El-Boray and H.A. Elgebaly,
Pharm. Biol.,
| Journal Article

Sabry Ali Abdallah El-Naggar
2015
Susceptibility of hedgehog, Hemiechinus auritus to Schistosoma mansoni under experimental infection.
Al-Sharkawi, M.I., A. El-Naggar, Sabry, A. E. El-Shaikh, Kamal, M. Al-Wahsh, Hany.,
Res. J. Parastitol,
| Journal Article

Sabry Ali Abdallah El-Naggar
2014
Impact of a toll-like receptor 3 ligand polyinosinic-cytidylic acid poly(I:C) administration on natural killer cells in absence or presence of peptide vaccination.
El-Naggar, S.A.,
Egypt. J. Exp. Biol. (Zool.),
| Journal Article

Sabry Ali Abdallah El-Naggar
2012
Kinetics of rebounding of lymphoid and myeloid cells in mouse peripheral blood, spleen and bone marrow after treatment with cyclophosphamide.
Salem, M.L., A.A. Al-Khami, S.A. El-Nagaar, A.A.A. Zidan, I.M. Al-Sharkawi, C.M. Diaz-Montero and D.J. Cole,
Cell. Immunol.,
| Journal Article

Sabry Ali Abdallah El-Naggar
2012
Susceptibility of some wild rodents widely distributed in Egyptian Foci to Schistosoma mansoni infection under laboratory conditions.
El-Naggar, S.A., I.M. Al-Sharkawi and G.A. Madkour,
Int. J. Zool. Res.,
| Journal Article

Sabry Ali Abdallah El-Naggar
2011
Anti-tumor activity of some 1,3,4-thiadiazoles and 1,2,4-triazine derivatives against ehrlichs ascites carcinoma.
El-Naggar, S.A., A.A. El-Brabary, M.A. Mansour, F. Abdel-Shafy and S. Talat,
Int. J. Cancer Res.,
| Journal Article

Sabry Ali Abdallah El-Naggar
2011
Lack of the beneficial effects of mirazid (Commiphora molmol) when administered with chemotherapeutic agents on ehrlich ascetic carcinoma bearing mice.
El-Naggar, S.A.,
Adv. Biol. Res.,
| Journal Article

Sabry Ali Abdallah El-Naggar
2011
Cyclophosphamide induces dynamic alterations in the host microenvironments resulting in a Flt3 ligand-dependent expansion of dendritic cells.
Salem, M.L., A.A. Al-Khami, S.A. El-Naggar, C.M. Diaz-Montero and D.J. Cole,
J. Immunol.,
| Journal Article

Sabry Ali Abdallah El-Naggar
2010
Cyclophosphamide induces bone marrow to yield higher numbers of precursor dendritic cells in vitro capable of functional antigen presentation to T cells in vivo.
Salem, M.L., S.A. El-Naggar and D.J. Cole,
Cell. Immunol.,
| Journal Article

Sabry Ali Abdallah El-Naggar
2010
Plasticity of T cell differentiation: A double-edged sword for immune responses.
Salem, M.L., F.Q. Alenzi, N. Nath, S.A. El-Naggar and A.A., Al-Khami et al.,
Immunol. Endocrine Metab. Agents Med. Chem. J.,
| Journal Article

Sabry Ali Abdallah El-Naggar
2009
Recovery from cyclophosphamide-induced lymphopenia results in expansion of immature dendritic cells which can mediate enhanced prime-boost vaccination antitumor responses in vivo when stimulated with the TLR3 agonist poly (I:C).
Salem, M.L., C.M. Diaz-Montero, A.A. Al-Khami and S.A. El-Naggar et al.,
J. Immunol.,
| Journal Article

Sabry Ali Abdallah El-Naggar
2009
Priming of naive CD8+ T cells in the presence of IL-12 selectively enhances the survival of CD8+CD62Lhi cells and results in superior anti-tumor activity in a tolerogenic murine model.
Diaz-Montero, C.M., S.A. El Naggar, A. Al Khami, R. El Naggar, A.J. Montero, D.J. Cole and M.L. Salem,
Cancer Immunol. Immunother.,
| Journal Article

Sabry Ali Abdallah El-Naggar
2008
TLR3 agonist poly(I:C) targets CD8+ T cells and augments their antigen-specific responses upon their adoptive transfer into naive recipient mice vaccine.
Salem, M.L., C.M. Diaz-Montero, S.A. El-Naggar, Y. Chen, O. Moussa and D.J. Cole,
Epub.,
| Journal Article

Sabry Ali Abdallah El-Naggar
2008
Defining the ability of Cyclophosphamide preconditioning to enhance the antigen-specific CD8+T-cell response to peptide vaccination: Creation of a beneficial host microenvironment involving type I IFNs and myeloid cells.
Salem, M.L., A.N. Kadima, S.A. El-Naggar, M.P. Rubinstein, Y. Chen, W.E. Gillanders and D.J. Cole,
J. Immunother.,
| Journal Article

Sabry Ali Abdallah El-Naggar
2007
Novel non-viral delivery approaches for Interleukin-12 protein and gene systems: curbing toxicity and enhancing adjuvant activity.
Salem, M.L., W.E. Gillanders, A.N. Kadima, S. El-Naggar and M.P. Rubinstein et al.,
J. Interferon. Cytokine Res.,
| Journal Article

Sabry Ali Abdallah El-Naggar
2006
The adjuvant effects of the toll-like receptor 3 ligand polyinosinic-cytidylic acid poly (I:C) on antigen-specific CD8+ T cell responses are partially dependent on NK cells and macrophages with the induction of a beneficial cytokine milieu.
Salem, M.L., S.A. EL-Naggar, A. Kadima, W.E. Gillanders and D.J. Cole,
Vaccine,
| Journal Article

Sabry Ali Abdallah El-Naggar
2006