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Manal Abdel Aziz Hamed

Manal Abdel Aziz Hamed

LiveDNA ID: 20.1802
ACSE
55 Publications
0 Editorial Roles
0 Projects

About

Professional Summary

Dr. Manal Abdel Aziz Hamed is a Professor of Biochemistry at National Research Center, Dokki, Cairo, Egypt. She obtained her Ph.D. in Biochemistry from same Institute. Her area of interest related to Biomedical Sciences, Biology, Biochemistry, and Enzymology. Her area of expertise includes Biology, Biochemistry, Enzymology, Molecular Biology, and Biomedical Sciences. She has published 56 articles in journals as author/co-author.

Education

Academic Background
  • Ph.D. National Research Center, Dokki, Cairo, Egypt Biochemistry | Completed: 2001

Publications (55)

Selected Scholarly Contributions
Bioactive phytochemicals from Severinia buxifolia target coagulation, inflammation and oxidative stress in experimental vein thrombosis
Manal A. Hamed, Sylvia E. Shaker, Wessam M. Aziz, Asmaa F. Aboul Nasser, Nagy S. El-Rigal, Wagdy K.B. Khalil, Walid E. Abdallah, Ali M. El-Hagrassi
Pharmacological Research - Natural Products | Journal Article
10.1016/j.prenap.2026.100732
Crossref
2026
GC/MS and LC‐ESI‐MS Analysis of Conocarpus erectus Leaves Extract via Regulating Amyloid‐β‐Peptide, Tau Protein, Neurotransmitters, Inflammation and Oxidative Stress against AlCl3‐Induced Alzheimer's Disease in Rats
Noha N. Nasr, Ali M. El‐Hagrassi, Yomna R. Ahmed, Manal A. Hamed
Chemistry & Biodiversity | Journal Article
10.1002/cbdv.202401960
Crossref
2025
GC/MS Analysis and Compounds Isolation of Lycium shawii Petroleum Ether Seeds Extract for Regulating Nrf2/OH‐1 Pathway, Oxidative Stress, and Inflammation in Acrylamide‐Induced Infertility in Female Rats
Noha N. Nasr, Marwa M. Elbatanony, Manal A. Hamed
Chemistry & Biodiversity | Journal Article
10.1002/cbdv.202401102
Crossref
2025
GC/MS and LC–ESI–MS/MS Analysis of Cucurbita pepo L. Aerial Parts Methanolic Extract via Regulating Oxidative Stress and Inflammatory Mediators Against Acrylamide‐Induced Nephrotoxicity in Rats Supported by In Silico Investigations
Enaam M. AbouZeid, Marwa M. Elbatanony, Yomna R. Ahmed, Manal A. Hamed
Chemistry & Biodiversity | Journal Article
10.1002/cbdv.202402856
Crossref
2025
Potential therapeutic effects of interleukin-1 receptor type 1 antagonist and the ethyl acetate fraction of Murraya exotica leaves against κ-carrageenan induced vein thrombosis in rats
Asmaa F. Aboul Naser, Wessam M. Aziz, Amal M. El-Feky, Marwa M. Elbatanony, Noha N. Nasr, Yomna R. Ahmed, Sylvia E. Shaker, Wagdy K.B. Khalil, Manal A. Hamed
Phytomedicine Plus | Journal Article
10.1016/j.phyplu.2025.100795
Crossref
2025
Metabolomic Profiling of Aegle marmelos Leaves Butanol Fraction and TNF‐α Receptor‐2 Antagonist in Treatment of Venous Thrombosis via Receptor Blockade and Gene Expression Modulation
Mona A. Mohammed, Noha N. Nasr, Yomna R. Ahmed, Asmaa F. Aboul Naser, Wagdy K. B. Khalil, Manal A. Hamed
ChemistrySelect | Journal Article
10.1002/slct.202504994
Crossref
2025
Therapeutic potential of pectin from various sources against diabetes mellitus in rats: AKT/PI3K/GSK-3β/CREB signaling pathways, inflammation, oxidative stress and genotoxicity crosstalk
Yomna R. Ahmed, Rehab M. Abdel-Megeed, Samar M. Gooda, Nahla N. Kamel, Gehan F. Abdel Raoof, Entesar E. S. Hassan, Ayman A. Farghaly, Mohamed A. El-Saied, Nagy S. El-Rigal, Maha Z. Rizk, Manal A. Hamed
Journal of Diabetes & Metabolic Disorders | Journal Article
10.1007/s40200-025-01776-5
Crossref
2025
Biosynthesis of Zinc Oxide Nanoparticles Using Bacillus paramycoides for In Vitro Biological Activities and In Vivo Assessment Against Hepatorenal Injury Induced by CCl4 in Rats
Heba A. El-Refai, Alaa M. Saleh, Shimaa I. A. Mohamed, Asmaa F. Aboul Naser, Rania A. Zaki, Sanaa K. Gomaa, Manal A. Hamed
Applied Biochemistry and Biotechnology | Journal Article
10.1007/s12010-023-04817-y
Crossref
2024
Inflammatory mediators, oxidative stress and genetic disturbance in rheumatoid arthritis rats supported by alfalfa seeds metabolomic constituents via blocking interleukin‐1receptor.
Asmaa F. Aboul Naser, Yomna R. Ahmed, Mona A. Mohammed, Mohamed Aboelmagd, Mona E. Aboutabl, Entesar E. Hassan, Wagdy K. B. Khalil, Manal A. Hamed
Chemistry & Biodiversity | Journal Article
10.1002/cbdv.202301653
Crossref
2024
Biogenic synthesized SeONPs by Bacillus paramycoides as antimicrobial, anticancer, antioxidant, apoptotic and hepatorenal treating agent.
Heba A. El Refai, Shimaa I.A. Mohamed, Asmaa F. Aboul Naser, Alaa M. Saleh, Sanaa K. Gomaa, Rania A. Zaki, Manal A. Hamed
Biocatalysis and Agricultural Biotechnology | Journal Article
10.1016/j.bcab.2024.103080
Crossref
2024
Mitigating Effect of Lepidium sativum Seeds Oil on Ovarian Oxidative Stress, DNA Abnormality and Hormonal Disturbances Induced by Acrylamide in Rats
Asmaa F. Aboul Naser, Amal M. El‐Feky, Manal A. Hamed
Chemistry & Biodiversity | Journal Article
10.1002/cbdv.202400062
Crossref
2024
Callus production of globe artichoke and milk thistle: In vitro hypolipidemic and antioxidant activities.
Bekheet, S.A., M.K. El-Bahr, S.A. Ali and M.A. Hamed,
World J. Pharm. Res., | Journal Article
Self Manal Abdel Aziz Hamed
2014
Performance of DNA of susceptible and resistant biomphalaria alexandrina snails as immunogens in schistosoma mansoni infected mice.
Hamed, M.A., H.F. Aly, S.A. Ali, N.S. El-Rigal and N.S. Metwally et al.,
World J. Pharm. Res., | Journal Article
Self Manal Abdel Aziz Hamed
2014
Assessment of Ficus Spp. in improving the metabolic syndrome secondary to hypercholesterolemia in rats fed with high-fat diet.
Awad, N.E., S.A. Ali, M.A. Hamed, A.A. Seida and M.M. Elbatanony,
Int. J. Pharm. Clin. Res., | Journal Article
Self Manal Abdel Aziz Hamed
2014
Trace elements, heavy metals and vitamins in Egyptian school children with iron deficiency anemia.
Nassef, Y.E., M.A. Shady, M. Mansour and M.A.A. Hamed,
J. Pediatric Biochem., | Journal Article
10.3233/JPB-140123
Self Manal Abdel Aziz Hamed
2014
Inflammatory cytokines, apoptotic, tissue injury and remodeling biomarkers in children with congenital heart disease.
Nassef, Y.E., M.A. Hamed and H.F. Aly,
Indian J. Clin. Biochem., | Journal Article
10.1007/s12291-013-0341-0
Self Manal Abdel Aziz Hamed
2014
Time series trend of bilharzial bladder cancer in Egypt and its relation to climate change: a study from 1995-2005.
Ahmed, S.A., A.S. Hussein, A.E. Feel and M.A. Hamed,
Int. J. Pharm. Clin. Res., | Journal Article
Self Manal Abdel Aziz Hamed
2014
Evaluation of the role of vitamin D levels in predicting chronic liver disease development in a group of Egyptian children infected with the hepatitis C virus.
Shady, M.M.A., Y.E. Nassef, M. Mansour, E.M. Galal and M.A. Hamed,
Med. Res. J., | Journal Article
10.1097/01.MJX.0000437953.50631.0c
Self Manal Abdel Aziz Hamed
2013
Non-viral factors contributing to hepatocellular carcinoma.
Hamed, M.A. and S.A. Ali,
World J. Hepatol. | Journal Article
Self Manal Abdel Aziz Hamed
2013
Impact of β-alanyl-L-histidine against Hypercholesterolemia.
Ali, S.A., M.A. Hamed and N.S. El Rigal,
J. Pharmacol. Toxicol. Stud., | Journal Article
Self Manal Abdel Aziz Hamed
2013
Molecular approach for detection compatibility/incompatibility of Egyptian Biomphalaria alexandrina and Bulinus truncates snails with their miracidia.
Rizk, M.Z., W.K.B. Khalil, A.H.Z. Abdel-Hamid, S.H. Haggag and M.A. Hamed et al.,
Int. J. Pharm. Clin. Res., | Journal Article
Self Manal Abdel Aziz Hamed
2013
Performance of diagnostic biomarkers in predicting liver fibrosis among hepatitis C virus-infected Egyptian children.
Nassef, Y.E., M.M.A. Shady, E.M. Galal and M.A. Hamed,
Mem. Inst. Oswaldo Cruz Rio de Janeiro, | Journal Article
10.1590/0074-0276130139
Self Manal Abdel Aziz Hamed
2013
Evaluation of G6PD activity and antioxidants status in jaundiced Egyptian neonates.
Nassef, Y.E., H.A. Fathy, A. Ali, M.A. Hamed and G.A. Fathy,
Int. J. Med. Med. Sci., | Journal Article
Self Manal Abdel Aziz Hamed
2013
Golden berry juice attenuates the severity of hepatorenal injury.
El-Gengaihi, S.E., M.A. Hamed, A.E.R.M. Khalaf-Allah and M.A. Mohammed,
J. Diet. Suppl., | Journal Article
10.3109/19390211.2013.830675
Self Manal Abdel Aziz Hamed
2013
Chemical composition and biological evaluation of Physalis peruviana root as hepato-renal protective agent.
El-Gengaihi, S.E., E.E. Hassan, M.A. Hamed, H.G. Zahran, and M.A. Mohammed,
J. Diet. Suppl., | Journal Article
10.3109/19390211.2012.760509
Self Manal Abdel Aziz Hamed
2013
Effects of black seed oil on resolution of hepato-renal toxicity induced by bromobenzene in rats.
Hamed, M.A., N.S. El-Rigal and S.A. Ali,
Eur. Rev. Med. Pharm. Sci., | Journal Article
Self Manal Abdel Aziz Hamed
2013
Therapeutic Potential of Ginger against Renal Injury Induced by Carbon Tetrachloride in Rats
Manal A. Hamed, Sanaa A. Ali, Nagy Saba El-Rigal
The Scientific World Journal | Journal Article
10.1100/2012/840421
Crossref
2012
In vitro and in vivo assessment of some functional foods against initiation of hepatocellular carcinoma.
Hamed, M.A., H.F. Aly, S.A. Ali, N.S. Metwalley, S.A. Hassan and S.A. Ahmed,
J. Basic Applied Sci. Res., | Journal Article
Self Manal Abdel Aziz Hamed
2012
Chemical composition and nutritional effect of Physalis peruviana husk as hepato-renal protective agent.
El-Gengaihi, S., M. Hamed, E.E.D. Hassan, H. Zahran and M. Arafa,
Int. J. Phytomed., | Journal Article
Self Manal Abdel Aziz Hamed
2012
Flavones composition and therapeutic potential of Dodonaea viscosa against liver fibrosis.
Shalaby, N.M.M., H.I. Abd-Alla, M.A. Hamed, S.N. Al-Ghamdi and S.M.S. Jambi,
Int. J. Phytomed., | Journal Article
Self Manal Abdel Aziz Hamed
2012
Correlation between steroid sex hormones, egg laying capacity and cercarial shedding in Biomphalaria alexandrina snails after treatment with Haplophyllum tuberculatum.
Rizk, M.Z., N.S. Metwally, M.A. Hamed and A.M. Mohamed,
Exp. Parasitol., | Journal Article
10.1016/j.exppara.2012.06.011
Self Manal Abdel Aziz Hamed
2012
Efficacy of Ficus spp. on renal injury induced by hypercholesterolaemia.
Awad, N.E., M.A. Hamed, A.A. Seida and M.M. Elbatanony,
Nat. Product Res., | Journal Article
10.1080/14786419.2011.570760
Self Manal Abdel Aziz Hamed
2012
Protective and therapeutic effects of Argyreia speciosa against ethanol-induced gastric ulcer in rats.
Motawi, T.K., M.A. Hamed, R.M. Hashem, M.H. Shabana and Y.R. Ahmed,
Z Naturforsch C., | Journal Article
Self Manal Abdel Aziz Hamed
2012
Phytochemical and in vitro screening of some Ficus and Morus spp. for hypolipidaemic and antioxidant activities and in vivo assessment of Ficus mysorensis (Roth).
Awad, N.E., A.A. Seida, M.A. Hamed, A.H. Mahmoud and M.M. Elbatanony,
Nat. Product Res., | Journal Article
10.1080/14786419.2010.545353
Self Manal Abdel Aziz Hamed
2012
Malachite green induces genotoxic effect and biochemical disturbances in mice.
Donya, S.M., A.A. Farghaly, M.A. Abo-Zeid, H.F. Aly and S.A. Ali et al.,
Eur. Rev. Med. Pharm. Sci., | Journal Article
Self Manal Abdel Aziz Hamed
2012
Efficiency of diagnostic biomarkers among colonic schistosomiasis Egyptian patients.
Hamed, M.A., S.A. Ahmed and H.M. Khaled,
Mem. Inst. Oswaldo Cruz, Rio de Janeiro, | Journal Article
Self Manal Abdel Aziz Hamed
2011
Potency of detergents in enhancing Schistosoma mansoni tegumental antigen.
Hamed, M.A.,
J. Infect. Dev. Ctries, | Journal Article
Self Manal Abdel Aziz Hamed
2011
Metabolic profile of rats after one hour of intoxication with a single oral dose of ethanol.
Hamed, M.A.,
J. Pharmacol. Toxicol., | Journal Article
10.3923/jpt.2011.158.165
Self Manal Abdel Aziz Hamed
2011
Hypolipidaemic and antioxidant activities of Ficus microcarpa (L.) in hypercholesterolemic rats.
Awad, N.E., A.A. Seida, M.A. Hamed and M.M. Elbatanony,
Nat. Product Res., | Journal Article
10.1080/14786419.2010.538015
Self Manal Abdel Aziz Hamed
2011
Beneficial effect of Ficus religiosa Linn. on high-fat-diet-induced hypercholesterolemia in rats.
Hamed, M.A.,
Food Chem., | Journal Article
10.1016/j.foodchem.2011.04.066
Self Manal Abdel Aziz Hamed
2011
Antischistosomal activity of Fasciola gigantic eggs influenced by Egyptian saponin extracted from Atriplex nummularia.
Maghraby, A.S., M.A. Hamed, H.F. Ali and S.A. Ali,
J. Am. Sci., | Journal Article
Self Manal Abdel Aziz Hamed
2010
Bioimmunological response to Schistosoma mansoni and Fasciola gigantica worm homogenates either mixed with or without saponin.
Maghraby, A.S., M.A. Hamed and S.A. Ali,
J. Infect. Dev. Countries, | Journal Article
Self Manal Abdel Aziz Hamed
2010
Biomphalaria alexandrina snails as immunogens against Schistosoma mansoni infection in mice.
Hamed, M.A., S.A. Ali, H.F. Aly, N.S. El-Rigal and M.Z. Rizk,
Mem. Inst. Oswaldo Cruz., | Journal Article
10.1590/S0074-02762010000700007
Self Manal Abdel Aziz Hamed
2010
Strategic control of schistosome intermediate host.
Hamed, M.A.,
Asian J. Epidemiol., | Journal Article
10.3923/aje.2010.123.140
Self Manal Abdel Aziz Hamed
2010
Therapeutic effect of L-carnosine on metabolic syndrome induced by hypercholesterolemia.
Ali, S.A., M.A. Hamed and N.S. El-Rigal,
The New Egypt. J. Med., | Journal Article
Self Manal Abdel Aziz Hamed
2009
Effect of vitamin C on serum protein profile in mice after aluminum sulphate intoxication.
Hamed, M.A.,
Pol. J. Food Nutr. Sci., | Journal Article
Self Manal Abdel Aziz Hamed
2006
Excretory secretory product of Fasciola hepatica worm protects against Schistosoma mansoni infection in mice.
Hamed, M.A.,
Indian J. Exp. Biol., | Journal Article
Self Manal Abdel Aziz Hamed
2006
Effect of Ailanthus altissima and Zizyphus spina-christi on bilharzial infestation in mice: Histological and histopathological studies.
Ali, S.A. and M.A. Hamed,
J. Applied Sci., | Journal Article
10.3923/jas.2006.1437.1446
Self Manal Abdel Aziz Hamed
2006
Hepatoprotective effect of carnosine on liver biochemical parameters in chronic ethanol intoxicated rat.
Soliman, K.M., M.A. Hamed and S.A. Ali,
J. Medical Sci., | Journal Article
10.3923/jms.2006.528.536
Self Manal Abdel Aziz Hamed
2006
Biochemical studies on hepatocytes after immunization of mice with schistosomal worm and egg antigens.
Bashtar, A., S.A. Ahmed, A.M. Soliman and M.A. Hamed,
Asian J. Biochem., | Journal Article
10.3923/ajb.2006.224.235
Self Manal Abdel Aziz Hamed
2006
The corrective action of L-carnosine and fluvastatin on certain biochemical parameters in hypercholesterolemic rabbits.
Soliman, K.M., M.A. Hamed, H.F. Aly,
Egypt. Med. J. NRC, | Journal Article
Self Manal Abdel Aziz Hamed
2005
Efficacy of Citrus reticulata and Mirazid in treatment of Schistosoma mansoni.
Hamed, M.A. and M.H. Hetta,
Mem. Inst. Oswaldo Cruz, | Journal Article
Self Manal Abdel Aziz Hamed
2005
Influence of Capparis spinosa and Acacia arabica on certain biochemical parameters in haemolymph of Biomphalaria alexandrina snails.
Mantawy, M.M., M.A. Hamed, E.M. Sammour and M. Sanad,
J. Egypt. Soc. Parasitol., | Journal Article
Self Manal Abdel Aziz Hamed
2004
Selected some biochemical parameters used as new markers for diagnosis of bladder cancer.
Aly, H.F., M.A. Hamed, S.A. Ahmed, H.M. Khaled,
Egypt. J. Schistosomiasis Infect. Endem. Dis., | Journal Article
Self Manal Abdel Aziz Hamed
2004
Prophylactic effect of Pulicaria crispa and Citharexylum quadrangular Jacq extracts on some liver enzymes representing different metabolic pathways in Schistosoma mansoni infected mice.
Hamed, M.A. H.F. Aly, S.A. Aly and A.S. Maghraby,
Egypt. J. Schitisomaiasis Infect. Endem. Dis., | Journal Article
Self Manal Abdel Aziz Hamed
2004