Education
Academic Background-
Ph.D. Tehran University of Medical Sciences, Tehran, Iran Medicinal Chemistry | Completed: 2009
Publications (32)
Selected Scholarly Contributions
In silico screening of IL-1β production inhibitors using chemometric tools.
Amir Hossein Sakhteman
2017
PLS-LS-SVM based modeling of ATR-IR as a robust method in detection and qualification of alprazolam.
Amir Hossein Sakhteman
2017
Binding mode of triazole derivatives as aromatase inhibitors based on docking, protein ligand interaction fingerprinting and molecular dynamics simulation studies.
Amir Hossein Sakhteman
2017
In silico analysis of drug resistance in HIV-reverse transcriptase inhibitors.
Amir Hossein Sakhteman
2017
A comparative QSAR analysis, molecular docking and PLIF studies of some N-arylphenyl-2,2-dichloroacetamide analogues as anticancer agents.
Amir Hossein Sakhteman
2017
3D-QSAR studies of some reversible Acetyl cholinesterase inhibitors based on CoMFA and ligand protein interaction fingerprints using PC-LS-SVM and PLS-LS-SVM.
Amir Hossein Sakhteman
2017
Modelface: An Application Programming Interface (API) for homology modeling studies using Modeller software.
Amir Hossein Sakhteman
2016
A Quantitative Structure-Activity Relationship (QSAR) study of some diaryl urea derivatives of B-RAF inhibitors.
Amir Hossein Sakhteman
2016
Insilico analysis of three different tag polypeptides with dual roles in scFv antibodies.
Amir Hossein Sakhteman
2016
Exploring Quantitative Structure-Activity Relationship (QSAR) models for some biologically active catechol structures using PC-LS-SVM and PC-ANFIS.
Amir Hossein Sakhteman
2016
A comparative docking studies of dichloroacetate analogues on four isozymes of pyruvate dehydrogenase kinase in humans.
Amir Hossein Sakhteman
2016
Trachyspermum ammi hydrosol, an almost pure source of thymol; analysis of the recovered essential oil from different samples.
Amir Hossein Sakhteman
2015
Synthesis and biological evaluation of 5-benzylidenerhodanine-3-acetic acid derivatives as AChE and 15-LOX inhibitors.
Amir Hossein Sakhteman
2015
Indolinone-based acetylcholinesterase inhibitors: Synthesis, biological activity and molecular modeling.
Amir Hossein Sakhteman
2014
Synthesis and docking studies of some 3-amino-6-(thiophen-2-yl)thieno[2,3-b]pyridine derivatives.
Amir Hossein Sakhteman
2013
Synthesis and evaluation of 4-substituted coumarins as novel acetylcholinesterase inhibitors.
Amir Hossein Sakhteman
2013
Design, synthesis, biological evaluation and docking study of 5-oxo-4,5-dihydropyrano[3,2-c]chromene derivatives as acetylcholinesterase and butyrylcholinesterase inhibitors.
Amir Hossein Sakhteman
2013
Design, synthesis, docking study and biological evaluation of some novel tetrahydrochromeno [3′,4′:5,6]pyrano[2,3-b]quinolin-6(7H)-one derivatives against acetyl- and butyrylcholinesterase.
Amir Hossein Sakhteman
2013
5-Nitro-heteroarylidene analogs of 2-thiazolylimino-4-thiazolidinones as a novel series of antibacterial agents.
Amir Hossein Sakhteman
2013
Novel coumarin-3-carboxamides bearing N-benzylpiperidine moiety as potent acetylcholinesterase inhibitors.
Amir Hossein Sakhteman
2013
Synthesis of some new 3-C oumaranone and coumarin derivatives as dual inhibitors of acetyl- and butyrylcholinesterase.
Amir Hossein Sakhteman
2013
Synthesis and evaluation of some novel methylene-bridged aryl semicarbazones as potential anticonvulsant agents.
Amir Hossein Sakhteman
2012
Synthesis and SAR study of 4,5-diaryl-1H-imidazole-2(3H)-thione derivatives, as potent 15-lipoxygenase inhibitors.
Amir Hossein Sakhteman
2012
Novel coumarin derivatives bearing N-benzyl pyridinium moiety: Potent and dual binding site acetylcholinesterase inhibitors.
Amir Hossein Sakhteman
2012
Antinociceptive activity of some 1,4-substituted piperidine derivatives using tail flick method in mice.
Amir Hossein Sakhteman
2011
Studying the catechol binding cavity in comparative models of human dopamine D2 receptor.
Amir Hossein Sakhteman
2011
Synthesis of 1-benzyl-4-[2-(3-thienylcarbonylamino)ethyl]piperidine as a novel potential cholinesterase inhibitor.
Amir Hossein Sakhteman
2011
Synthesis and dopaminergic activity of some E-3-(piperidin-1-yl)-1-(4-substituted phenyl)prop-2-en-1-one derivatives.
Amir Hossein Sakhteman
2009
Synthesis and structure-activity relationship study of 2-substituted-5-(5-nitro-2-thienyl)-1,3,4-thiadiazoles as anti-Helicobacter pylori agents.
Amir Hossein Sakhteman
2009
Synthesis and anticonvulsant activity of novel 2-amino-5-[4-chloro-2-(2-chlorophenoxy) phenyl]-1,3,4-thiadiazole derivatives.
Amir Hossein Sakhteman
2007
Synthesis, antituberculosis activity and QSAR study of some novel 2-(nitroaryl)-5-(nitrobenzylsulfinyl and sulfonyl)-1,3,4-thiadiazole derivatives.
Amir Hossein Sakhteman
2007
Synthesis and antimycobacterial activity of some alkyl [5-(nitroaryl)-1,3,4-thiadiazol-2-ylthio]propionates.
Amir Hossein Sakhteman
2006