About
Professional SummaryExperienced Scientist with a demonstrated history of working in the Biomedical and drug design industry. Currently concentrating application of network pharmacology especially on gene expression of coding and noncoding RNAs, DNA adducts, gene regulatory networks, protein-protein interaction network on lung cancer research. Strong research professional skilled in Autodock, NAMD, Vaccines Design, WGCNA, Cytoscape, experimental animal models, Molecular Biology, Biotechnology, and plant cell culture.
Education
Academic Background-
Certificate Course Concordia University, Montreal, Canada Teaching Learning Assessment | Completed: 2020
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Ph.D. Annamalai University, Tamil Nadu, India Biotechnology | Completed: 2014
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M.Sc. Annamalai University, Tamil Nadu, India Marine Biotechnology | Completed: 2008
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B.Sc. Bharathiar University, Coimbatore, India Biochemistry | Completed: 2006
Publications (95)
Selected Scholarly Contributions
Unveiling Novel Metalloprotease Inhibitors Targeting Botulinum Neurotoxin Through Structure-Based Virtual Screening of Drug Libraries and Molecular Dynamics Simulations
2026
Quercetin and carvacrol act synergistically to inhibit Candida albicans biofilms in vitro via membrane disruption and oxidative stress
2026
Genome-scale metabolic models in translational medicine: the current status and potential of machine learning in improving the effectiveness of the models
2024
Insights into dietary phytochemicals targeting Parkinson's disease key genes and pathways: A network pharmacology approach
2024
Prospects of Novel and Repurposed Immunomodulatory Drugs against Acute Respiratory Distress Syndrome (ARDS) Associated with COVID-19 Disease
2023
Integrated RNA-sequencing and network analysis approach to identify the Hub genes and vital pathways associated with gastric cancer
2023
Advances in Drug Design and Development for Human Therapeutics Using Artificial Intelligence-II
2023
Advances in Drug Design and Development for Human Therapeutics Using Artificial Intelligence—I
2022
Identifying potential drug targets and candidate drugs for COVID-19: biological networks and structural modeling approaches
2021
Identifying potential drug targets and candidate drugs for COVID-19: biological networks and structural modeling approaches
2021
Identifying potential drug targets and candidate drugs for COVID-19: biological networks and structural modeling approaches
2021
Structure-Based Virtual Screening Reveals Ibrutinib and Zanubrutinib as Potential Repurposed Drugs against COVID-19
2021
Application of Artificial Intelligence in Drug Repurposing: A mini-review
2021
2021
Editorial: computational genomics and molecular medicine for emerging COVID-19.
Gurudeeban Selvaraj
2021
Are the allergic reactions of COVID-19 vaccines caused by mRNA constructs or nanocarriers? immunological insights.
Gurudeeban Selvaraj
2021
Circulating miR-1246 Targeting UBE2C, TNNI3, TRAIP, UCHL1 Genes and Key Pathways as a Potential Biomarker for Lung Adenocarcinoma: Integrated Biological Network Analysis
2020
A theoretical study of chemical bonding and topological and electrostatic properties of the anti-leprosy drug dapsone.
Gurudeeban Selvaraj
2020
Computational advances in chronic diseases diagnostics and therapy-II.
Gurudeeban Selvaraj
2020
Exploring the Papillomaviral Proteome to Identify Potential Candidates for a Chimeric Vaccine against Cervix Papilloma Using Immunomics and Computational Structural Vaccinology
2019
Immunomics Datasets and Tools: To Identify Potential Epitope Segments for Designing Chimeric Vaccine Candidate to Cervix Papilloma
2019
Cancer immunoinformatics: A promising era in the development of peptide vaccines for human papillomavirus-induced cervical cancer.
Gurudeeban Selvaraj
2019
Computational perspective on the current state of the methods and new challenges in cancer drug discovery.
Gurudeeban Selvaraj
2019
Viewing the emphasis on state-of-the-art magnetic nanoparticles: Synthesis, physical properties and applications in cancer theranostics.
Gurudeeban Selvaraj
2019
Synergism of essential oils with lipid based nanocarriers: emerging trends in preservation of grains and related food products.
Gurudeeban Selvaraj
2019
The relationship between Chlorella sp. and zinc oxide nanoparticles: Changes in biochemical, oxygen evolution and lipid production ability.
Gurudeeban Selvaraj
2019
Ion channels as therapeutic targets for type 1 diabetes mellitus.
Gurudeeban Selvaraj
2019
Combining in silico and in vitro approaches to identification of potent inhibitor against phospholipase A2 (PLA2).
Gurudeeban Selvaraj
2019
Computational advances in chronic diseases diagnostics and therapy-I.
Gurudeeban Selvaraj
2019
Designing of CD8+ and CD8+-overlapped CD4+ epitope vaccine by targeting late and early proteins of human papillomavirus.
Gurudeeban Selvaraj
2018
Identification of target gene and prognostic evaluation for lung adenocarcinoma using gene expression meta-analysis, network analysis and neural network algorithms.
Gurudeeban Selvaraj
2018
Prognostic impact of tissue inhibitor of metalloproteinase-1 in non- small cell lung cancer: Systematic review and meta-analysis.
Gurudeeban Selvaraj
2018
Towards the low-sensitive and high-energetic co-crystal explosive CL-20/TNT: From intermolecular interactions to structures and properties.
Gurudeeban Selvaraj
2018
RuBisCO of Microalgae as Potential Targets for Nutraceutical Peptides: A Computational Study
2017
2017
Detoxification of aflatoxins on prospective approach: Effect on structural, mechanical, and optical properties under pressures.
Gurudeeban Selvaraj
2017
Computational screening of anti-diabetic molecules from microalgae metabolites by molecular docking.
Gurudeeban Selvaraj
2017
Computational screening of dipeptidyl peptidase IV inhibitors from micoroalgal metabolites by pharmacophore modeling and molecular docking.
Gurudeeban Selvaraj
2016
Chemopreventive effect of Acanthus ilicifolius extract on modulating antioxidants, lipid peroxidation and membrane bound enzymes in diethyl nitrosamine induced liver carcinogenesis.
Gurudeeban Selvaraj
2016
Effect of Glycosin alkaloid from Rhizophora apiculata in non-insulin dependent diabetic rats and its mechanism of action: In vivo and in silico studies.
Gurudeeban Selvaraj
2016
Molecular docking studies of rutin on matrix metalloproteinase.
Gurudeeban Selvaraj
2016
Positive regulation of Rhizophora mucronata poir extracts on blood glucose and lipid profile in diabetic rats.
Gurudeeban Selvaraj
2016
Influence of rutoside loaded solid lipid nanoparticles to enhance oral bioavailability: Characterization, pharmacokinetic and pharmacodynamic studies.
Gurudeeban Selvaraj
2016
Production and characterization of spherical thermostable silver nanoparticles from Spirulina platensis (Cyanophyceae).
Gurudeeban Selvaraj
2016
Computational screening of dipeptidyl peptidase IV inhibitors from micoroalgal metabolites by pharmacophore modeling and molecular docking.
Gurudeeban Selvaraj
2016
Insight on solid lipid nanoparticles: Characterization and application in diabetes mellitus.
Gurudeeban Selvaraj
2016
Identification of medicinal mangrove Rhizophora apiculata Blume: morphological, chemical and DNA barcoding methods.
Gurudeeban Selvaraj
2015
Influence of Rhizophora apiculata flavonoids on chemical and thermal induced nociceptive models.
Gurudeeban Selvaraj
2015
Chemopreventive effect of acanthus ilicifolius extract on modulating antioxidants, lipid peroxidation and membrane bound enzymes in diethyl nitrosamine induced liver carcinogenesis.
Gurudeeban Selvaraj
2015
Floral system act as a reservoir for nanobiotechnology (silver nanoparticles).
Gurudeeban Selvaraj
2015
Antidiabetic and antihyperlipidemic effects of Rhizophora apiculata blume extracts.
Gurudeeban Selvaraj
2015
Formulation and evaluation of tablets from antidiabetic alkaloid glycosin.
Gurudeeban Selvaraj
2015
Antimicrobial and radical scavenging effects of alkaloid extracts from Rhizophora mucronata.
Gurudeeban Selvaraj
2015
Influence of Rhizophora apiculata flavonoids on chemical and thermal induced nociceptive models.
Gurudeeban Selvaraj
2015
Influence of Rhizophora apiculata Blume extracts on α-glucosidase: Enzyme kinetics and molecular docking studies.
Gurudeeban Selvaraj
2015
Identification of medicinal mangrove Rhizophora apiculata blume: Morphological, chemical and DNA barcoding methods.
Gurudeeban Selvaraj
2015
Chemical compositions of medicinal mangrove species Acanthus ilicifolius, Excoecaria agallocha, Rhizophora apiculata and Rhizophora mucronata.
Gurudeeban Selvaraj
2015
In vitro anticancer effect of Acanthus ilicifolius on hepatocellular carcinoma cells.
Gurudeeban Selvaraj
2014
Molecular docking studies of Rhizophora mucronata alkaloids against neuroinflammatory marker cyclooxygenase 2.
Gurudeeban Selvaraj
2014
Documentation of hypoglycemic and wound healing plants in Kodiyampalayam coastal village (Southeast coast of India).
Gurudeeban Selvaraj
2014
Qualitative and quantitative phytochemical studies of Acanthus ilicifolius.
Gurudeeban Selvaraj
2014
Molecular docking studies on potential PPAR-γ agonist from Rhizophora apiculata.
Gurudeeban Selvaraj
2014
Molecular docking, isolation and biological evaluation of Rhizophora mucronata flavonoids as anti-nociceptive agents.
Gurudeeban Selvaraj
2014
2014
Phylogeny of indian rhizophoraceae based on the molecular data from chloroplast trnaleuuaa intergenic sequences.
Gurudeeban Selvaraj
2013
Antimicrobial and radical scavenging effects of alkaloid extracts from Rhizophora mucronata.
Gurudeeban Selvaraj
2013
Direct organogenesis of seaside heliotrope (Heliotropium crassavicum) using stem explants.
Gurudeeban Selvaraj
2013
Standardization of genomic DNA isolation and molecular identification of Rhizophora sp. Using non-coding trn L gene.
Gurudeeban Selvaraj
2013
Phylogeny of Indian Rhizophoraceae based on the molecular data from chloroplast tRNALEUUAA intergenic sequences.
Gurudeeban Selvaraj
2013
Ipomoea pes-caprae mediated silver nanoparticles and their antibacterial effect.
Gurudeeban Selvaraj
2013
Heliotropium curassavicum mediated silver nanoparticles for environmental application.
Gurudeeban Selvaraj
2013
Effect of biochemical indicators for rooting in horsetail trees (Casuarina equisetifolia L.).
Gurudeeban Selvaraj
2013
Antidiabetic effect of a black mangrove species Aegiceras corniculatum in alloxan-induced diabetic rats.
Gurudeeban Selvaraj
2012
An In silico approach of alpha-ketoglutarate dependent Dioxygenase FTO inhibitors derived from Rhizophora mucronata.
Gurudeeban Selvaraj
2012
Alpha glucosidase inhibitory effect and enzyme kinetics of coastal medicinal plants.
Gurudeeban Selvaraj
2012
Dipeptidyl peptidase IV inhibitors derived from a mangrove flora Rhizophora mucronata: An in silico approach.
Gurudeeban Selvaraj
2012
Effect of antioxidant and anti-aggregating properties of micro-propagated plantlets of Ruta graveolens.
Gurudeeban Selvaraj
2012
Genetic identification of Ceriops decandra (Chiru Kandal) using tRNA (Leu) molecular marker.
Gurudeeban Selvaraj
2012
Toxicity study of silver nanoparticles synthesized from Suaeda monoica on Hep-2 cell line.
Gurudeeban Selvaraj
2012
Standardization of DNA isolation and PCR protocol for RAPD analysis of Suaeda sp.
Gurudeeban Selvaraj
2011
Plant mediated synthesis of biomedical silver nanoparticles by using leaf extract of Citrullus colocynthis.
Gurudeeban Selvaraj
2011
Production of extra cellular α-amylase using Bacillus megaterium isolated from white mangrove (Avicennia marina).
Gurudeeban Selvaraj
2011
Effect of plant growth regulators on callus induction and plantlet regeneration of bitter apple (Citrullus colocynthis) from stem explant.
Gurudeeban Selvaraj
2011
Local anesthetic effect of Citrullus colocynthis on rana hexadactyla.
Gurudeeban Selvaraj
2011
Characterization of volatile compounds from bitter apple (Citrullus colocynthis) using GC-MS.
Gurudeeban Selvaraj
2011
In vitro plantlet regeneration of gum-bearing tree Aegle marmelos.
Gurudeeban Selvaraj
2011
Green synthesis of silver nanoparticles by using stem derived callus extract of bitter apple (Citrullus Colocynthis).
Gurudeeban Selvaraj
2011
Bitter apple (Citrullus colocynthis): An overview of chemical composition and biomedical potentials.
Gurudeeban Selvaraj
2010
Antioxidant and radical scavenging effect of Citrullus colocynthis.
Gurudeeban Selvaraj
2010
Antioxidant and radical scavenging effect of a marine diatom species - Skeletonema costatum.
Gurudeeban Selvaraj
2010
Antioxidant and radical scavenging effect of Clerodendrum inerme (L.).
Gurudeeban Selvaraj
2010
Biochemical indicators for rooting in Casuarina equisetifolia clones.
Gurudeeban Selvaraj
2010
Evaluation of anti-inflammatory activity of Citrullus colocynthis.
Gurudeeban Selvaraj
2010
Antidiabetic effect of Citrullus colocynthis in alloxon-induced diabetic rats.
Gurudeeban Selvaraj
2010
Antimicrobial activity of Citrullus colocynthis in gulf of mannar.
Gurudeeban Selvaraj
2010