About
Professional SummaryDr Sadiq Umar is currently working as Postdoctoral Research Associate. He obtained his PhD degree in the field of Clinical Toxicology Lab, MSc in the field of Toxicology from Hamdard University, New Delhi, India in 2012 & 2007, respectively. His main area of interest includes Autoimmune Disease, Rheumatoid arthritis, Neurodegenerative disease. His area of expertise includes, Rheumatoid arthritis, Stroke, Inflammation, Oxidative stress, Cytokine, Animal model, Multiple sclerosis, Synovial fibroblast. Dr Sadiq Umar published 25 articles in journals as author/co-author.
Education
Academic Background-
Ph.D. Hamdard University, India Autoimmunity | Completed: 2012
Publications (29)
Selected Scholarly Contributions
A novel nanoformulation development of eugenol and their treatment in inflammation and periodontitis.
Sadiq Umar
2019
Synthesis of novel amide containing schiffs bases of 5-(4-chloro-phenyl)-furan-2-carboxaldehyde: Their in vivo anti-inflammatory, antioxidant and antinociceptive activities with ulcerogenic risk evaluation.
Sadiq Umar
2018
Impact of obesity on autoimmune arthritis and its cardiovascular complications.
Sadiq Umar
2018
In vivo anti-inflammatory activity and docking study of newly synthesized benzimidazole derivatives bearing oxadiazole and morpholine rings.
Sadiq Umar
2017
Regulation of transforming growth factor β-activated kinase activation by epigallocatechin-3-gallate in rheumatoid arthritis synovial fibroblasts: Suppression of K63-linked autoubiquitination of tumor necrosis factor receptor-associated factor 6.
Sadiq Umar
2016
Synthesis of novel oxazolo[4,5-b]pyridine-2-one based 1,2,3-triazoles as glycogen synthase kinase-3β inhibitors with anti-inflammatory potential.
Sadiq Umar
2016
Thymoquinone inhibits TNF-α-induced inflammation and cell adhesion in rheumatoid arthritis synovial fibroblasts by ASK1 regulation.
Sadiq Umar
2015
Anti-inflammatory effects of a novel ricinoleic acid poloxamer gel system for transdermal delivery.
Sadiq Umar
2015
Design, synthesis and docking studies of 2-benzoxazolinone-based 1, 2, 4-triazoles as proinflammatory cytokine inhibitors.
Sadiq Umar
2014
Synthesis of novel 2-mercaptobenzoxazole based 1, 2, 3-triazoles as inhibitors of proinflammatory cytokines and suppressors of COX-2 gene expression.
Sadiq Umar
2014
Boswellia serrata extract attenuates inflammatory mediators and oxidative stress in collagen induced arthritis.
Sadiq Umar
2014
Quercetin prevents protein nitration and glycolytic block of proliferation in hydrogen peroxide insulted cultured Neuronal Precursor Cells (NPCs): Implications on CNS regeneration.
Sadiq Umar
2013
A comparative study of PNIPAM nanoparticles of curcumin, demethoxycurcumin and bisdemethoxycurcumin and their effects on oxidative stress markers in experimental stroke.
Sadiq Umar
2013
Hesperidin inhibits collagen-induced arthritis possibly through suppression of free radical load and reduction in neutrophil activation and infiltration.
Sadiq Umar
2013
Piperine ameliorates oxidative stress, inflammation and histological outcome in collagen induced arthritis.
Sadiq Umar
2013
Anticonvulsant activity of methanolic and aqueous extracts of Melissa parviflora in experimentally induced Swiss albino mice.
Sadiq Umar
2012
Nephroprotective action of Peucedanum grande against cadmium chloride induced renal toxicity in Wistar rats.
Sadiq Umar
2012
Trigonella foenum graecum mitigates proteases and restores antioxidant balance in collagen induced arthritis in rats.
Sadiq Umar
2012
Anti-inflammatory and antioxidant activity of Trachyspermum ammi seeds in collagen induced arthritis in rats.
Sadiq Umar
2012
Protective effect of rutin in attenuation of collagen-induced arthritis in Wistar rat by inhibiting inflammation and oxidative stress.
Sadiq Umar
2012
Modulation of the oxidative stress and inflammatory cytokine response by thymoquinone in the collagen induced arthritis in Wistar rats.
Sadiq Umar
2012
Scorpion (Odontobuthus doriae) venom induces apoptosis and inhibits DNA synthesis in human neuroblastoma cells.
Sadiq Umar
2011
Upregulation of CSPG3 accompanies neuronal progenitor proliferation and migration in EAE.
Sadiq Umar
2011
Increased spontaneous apoptosis of rat primary neurospheres in vitro after experimental autoimmune encephalomyelitis.
Sadiq Umar
2011
Scorpion (Androctonus crassicauda) venom limits growth of transformed cells (SH-SY5Y and MCF-7) by cytotoxicity and cell cycle arrest.
Sadiq Umar
2011
Scorpion venom (Odontobuthus doriae) induces apoptosis by depolarization of mitochondria and reduces S-phase population in human breast cancer cells (MCF-7).
Sadiq Umar
2011
Synthesis, characterization, antiamoebic activity and cytotoxicity of novel series of pyrazoline derivatives bearing quinoline tail.
Sadiq Umar
2010
2010
Hippocampal neurodegeneration in Experimental Autoimmune Encephalomyelitis (EAE): potential role of inflammation activated myeloperoxidase.
Sadiq Umar
2009