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Senthil  Selvaraj

Senthil Selvaraj

LiveDNA ID: 91.358
14 Publications
0 Editorial Roles
0 Projects

About

Professional Summary

Dr. Senthil Selvaraj is currently working as Post-doctoral Fellow at Qatar Cardiovascular Research Center, Qatar. He obtained his Ph.D. in Biochemistry from Annamalai University, Tamil Nadu, India. His area of interest related to Calcium Signaling in Excitable & Non-excitable Cells, Signal Transduction (plasma membrane to nucleus), Membrane Microdomains (caveolae, focal adhesions), Gene Regulation (RNAi, miRNA, transcription). His professional experience includes over four years of Post Doctoral experience in School of Medicine & Health Sciences, UND, Pre Doctoral experience Cardio Vascular Diseases (CVD) and Free Radical Biology. Dr. Senthil Selvaraj received honors includes Madison’s Who’s Who of Executives and Professionals honors, New York, USA, Honorable Mention for poster presentation at 17th Biennial meeting of the ISDN, Asilomar, USA, Senior Research Fellowship, awarded by Indian Council of Medical Research, University Research Studentship, and Best Paper Award at the Indian Society for Atherosclerosis Research and International symposia/CME on atherosclerosis and XVIIIth annual conference of Indian Society of Atherosclerosis, New Delhi, India. He is member of Society for Free Radical Research (SFRR), India, and Indian Society of Atherosclerosis Research (ISAR), India. He is also serving as reviewer of some journals. He has published 1 article in journals, presented 2 invited oral presentations, and 18 abstracts and poster presentations as author/co-author.

Education

Academic Background
  • Ph.D. Annamalai University, Tamil Nadu, India Biochemistry | Completed: 2007
  • M.Phil. Annamalai University, Tamil Nadu, India Biochemistry | Completed: 2004
  • M.Sc. Annamalai University, Tamil Nadu, India Biochemistry | Completed: 2002
  • B.Sc. Goverment Arts College, Kumbakonam, India Chemistry | Completed: 2000

Publications (14)

Selected Scholarly Contributions
Intramolecular shielding maintains the ER Ca2+ sensor STIM1 in an inactive conformation.
Yu, F., L. Sun, S. Hubrack, S. Selvaraj and K. Machaca,
J. Cell Sci., | Journal Article
Self Senthil Selvaraj
2013
Increase in serum Ca2+/Mg2+ ratio promotes proliferation of prostate cancer cells by activating TRPM7 channels.
Sun, Y., S. Selvaraj, A. Varma, S. Derry, A.E. Sahmoun and B.B. Singh,
J. Biol. Chem., | Journal Article
Self Senthil Selvaraj
2013
In vitro antioxidant activities of Solanum surattense leaf extract.
Muruhan, S., S. Selvaraj and P.K. Viswanathan,
Asian Pac. J. Trop. Biomed., | Journal Article
Self Senthil Selvaraj
2013
Effect of ursolic acid on cardiac marker enzymes, lipid profile and macroscopic enzyme mapping assay in isoproterenol-induced myocardial ischemic rats.
Radhiga, T., C. Rajamanickam, S. Senthil and K.V. Pugalendi,
Food Chem. Toxicol., | Journal Article
Self Senthil Selvaraj
2012
Clavulanic acid inhibits MPP+-induced ROS generation and subsequent loss of dopaminergic cells.
Kost, G.C., S. Selvaraj, Y.B. Lee, D.J. Kim, C.H. Ahn and B.B. Singh,
Brain Res., | Journal Article
Self Senthil Selvaraj
2012
Neurotoxin-induced ER stress in mouse dopaminergic neurons involves downregulation of TRPC1 and inhibition of AKT/mTOR signaling.
Selvaraj, S., Y. Sun, J.A. Watt, S. Wang, S. Lei, L. Birnbaumer and B.B. Singh,
J. Clin. Invest., | Journal Article
Self Senthil Selvaraj
2012
Clavulanic acid increases dopamine release in neuronal cells through a mechanism involving enhanced vesicle trafficking.
Kost, G.C., S. Selvaraj, Y.B. Lee, D.J. Kim, C.H. Ahn and B.B. Singh,
Neurosci. Lett., | Journal Article
Self Senthil Selvaraj
2011
TRPC channels and their implications for neurological diseases.
Selvaraj, S., Y. Sun and B.B. Singh,
CNS Neurolog. Disorders-Drug Targets, | Journal Article
Self Senthil Selvaraj
2010
TRPC1 inhibits apoptotic cell degeneration induced by dopaminergic neurotoxin MPTP/MPP+.
Selvaraj, S., J.A. Watt and B.B. Singh,
Cell Calcium, | Journal Article
Self Senthil Selvaraj
2009
Cardioprotective effect of oleanolic acid on isoproterenol-induced myocardial ischemia in rats.
Senthil, S., M. Sridevi and K.V. Pugalendi,
Toxicol. Pathol., | Journal Article
Self Senthil Selvaraj
2007
Protective effect of ursolic acid against myocardial ischemia induced by isoproterenol in rats.
Senthil, S., G. Chandramohan and K.V. Pugalendi,
Toxicol. Mechanisms Methods, | Journal Article
Self Senthil Selvaraj
2007
Isomers (oleanolic and ursolic acids) differ in their protective effect against isoproterenol-induced myocardial ischemia in rats.
Senthil, S., G. Chandramohan and K.V. Pugalendi,
Int. J. Cardiol., | Journal Article
Self Senthil Selvaraj
2007
Redox status and lipid peroxidation in alcoholic hypertensive patients and alcoholic hypertensive patients with diabetes.
Veerappan, R.M., S. Senthil, M.R. Rao, R. Ravikumar and K.V. Pugalendi,
Clin. Chim. Acta, | Journal Article
Self Senthil Selvaraj
2004
Oxidative stress and antioxidants in patients with cardiogenic shock complicating acute myocardial infarction.
Senthil, S., R.M. Veerappan, M. Ramakrishna Rao and K.V. Pugalendi,
Clin. Chim. Acta, | Journal Article
Self Senthil Selvaraj
2004