About
Professional SummaryDr. Mohd Nazam Ansari is currently working as Assistant Professor at Department of Pharmacology, College of Pharmacy, Prince Sattam Bin Abdulaziz University, (Al-Kharj), Kingdom of Saudi Arabia. He has completed his Ph.D. in Pharmacology from Jamia Hamdard, New Delhi, India. During 2005 to 2007 he worked as Project Associate under Major Research Project Funded by University Grants Commission (UGC), Government of India. He is life member of Indian Pharmacological Society, India, and member of Indian Society for Technical Education, New Delhi, India. He is also serving as reviewer for Journal of Cardiovascular Pharmacology, Immunobiology, Toxicology Mechanisms and Methods, Pakistan Journal of Pharmaceutical Sciences, The Journal of the Renin-Angiotensin-Aldosterone System, Journal of Pharmacy Research and many others. Dr. Nazam received honors includes Travel Grant for Young Pharmacologists was awarded by Indian Pharmacological Society, recipient of University Grants Commission (UGC) Scholarship, and Registered Pharmacist-Delhi Pharmacy Council. He has completed 5 research projects as principal investigator and co-principal investigator. He has published 40 research articles in journals as well as 2 abstracts in scientific journals contributed as author/co-author. He also presented 8 abstract in scientific meeting. He also participated in number of workshop and training courses.
Education
Academic Background-
Ph.D. Jamia Hamdard, New Delhi, India Pharmacology | Completed: 2008
Editorial Services
Editorial & Publishing Roles
Editorial Board Member
Serving as Editorial Board Member for Journal of Pharmacology and Toxicology.
Publications (126)
Selected Scholarly Contributions
L-Arginine Schiff Bases for Diabetic Wound Healing via Nitric Oxide
Synthase Inhibition: Synthesis, In Vitro Activity, and In Silico Insights
2026
Diabetes-Associated
Cognitive Dysfunction: Pathophysiology,
Molecular Mechanisms, and Emerging Therapeutic Strategies
2026
Computational discovery of marine-derived modulators targeting SLC15A4 for autoimmune disease
2026
A Systematic Review of the Vascular and Neuronal Role of L-Carnosine: Mechanistic and Pharmacological Perspectives
2026
Discovery of Natural-product Chemotypes with Dual GSK-3ß/HDAC6 Binding Potential via Receptor-guided Pharmacophore Screening, Molecular Docking and Dynamics Simulations
2026
Designing & screening of siRNA molecules for silencing the impact of the VEGF gene in cancer cells
2026
Pharmacological basis for the traditional use of Myrica salicifolia root extract in gut motility disorders via cholinergic and calcium/PDE modulation
2026
Emerging Therapeutic Agents and Nanotechnology-Driven Innovations in Psoriasis Management
2025
Molecular Mechanisms and Therapeutic Targeting of Heat Shock Proteins (HSPs) in Cardiovascular Disorders
2025
Optimizing siRNA Therapeutics Targeting HIF-1α: Computational Design, Screening, and Molecular Dynamics Simulation Studies
2025
Inhibition of Activated Coagulation Factor XII by the Phosphodiesterase-4 Inhibitor Roflumilast: In Vitro and In Silico Studies
2025
Hepatoprotective effect of diosmetin against thioacetamide-induced liver injury via modulating Bax/NF-κB/caspase-3/Nrf-2/PPARϒ signaling pathway in rats
2025
Simultaneous determination of theobromine (THEOB), theophylline (THEOP) and caffeine (CAF) in commercially available food products using UPLC technique
2025
Network Pharmacology and Molecular Insights into Artemetin and Vitrofolal E of
Vitex negundo
against Diabetic Cardiomyopathy
2025
Myricetin alleviates indomethacin-induced gastric ulcers in rats via antioxidant, anti-inflammatory and antiapoptotic mechanisms
2025
Vorinostat polymeric nanoparticle gel: A promising therapy for management of psoriasis
2025
Calcium Channel Inhibitory Effect of Marjoram (Origanum majorana L.): Its Medicinal Use in Diarrhea and Gut Hyperactivity
2024
Investigating the Potential Impact of Air Pollution on Alzheimer’s Disease and the Utility of Multidimensional Imaging for Early Detection
2024
Emerging Trends of Nanomedicines in the Management of Prostate Cancer: Perspectives and Potential Applications
2024
An Insight on Microfluidic Organ-on-a-Chip Models for PM2.5-Induced Pulmonary Complications
2024
Exploring progress in iron supplement formulation approaches for treating iron deficiency anemia through bibliometric and thematic analysis
2024
Formulation of Phytosomes Containing Rubia cordifolia Extract for Neuropathic Pain: In Vitro and In Vivo Evaluation
2024
Molecular Docking of Bacterial Protein Modulators and Pharmacotherapeutics of Carica papaya Leaves as a Promising Therapy for Sepsis: Synchronising In Silico and In Vitro Studies
2023
Plant-Derived Bioactive Compounds in the Management of Neurodegenerative Disorders: Challenges, Future Directions and Molecular Mechanisms Involved in Neuroprotection
2023
An Overview of Nanoemulgels for Bioavailability Enhancement in Inflammatory Conditions via Topical Delivery
2023
Myrica salicifolia
Hochst. ex A. Rich. suppress acetic acid-induced ulcerative colitis in rats by reducing TNF-alpha and interleukin-6, oxidative stress parameters and improving mucosal protection
2022
In Silico and Ex Vivo Studies on the Spasmolytic Activities of Fenchone Using Isolated Guinea Pig Trachea
2022
GC–MS Analysis and In Vivo and Ex Vivo Antidiarrheal and Antispasmodic Effects of the Methanolic Extract of Acacia nilotica
2022
Dual Inhibition of Phosphodiesterase and Ca++ Channels Explains the Medicinal Use of Balanites aegyptiaca (L.) in Hyperactive Gut Disorders
2022
Crisaborole Loaded Nanoemulsion Based Chitosan Gel: Formulation, Physicochemical Characterization and Wound Healing Studies
2022
Degradation of Xenobiotic Pollutants: An Environmentally Sustainable Approach
2022
Wound Healing Potential of Commiphora gileadensis Stems Essential Oil and Chloroform Extract
2022
Investigation of Trends in the Research on Transferrin Receptor-Mediated Drug Delivery via a Bibliometric and Thematic Analysis
2022
The Detailed Pharmacodynamics of the Gut Relaxant Effect and GC-MS Analysis of the Grewia tenax Fruit Extract: In Vivo and Ex Vivo Approach
2022
Dysregulation of multiple signaling pathways: A possible cause of cerebral palsy.
Mohd. Nazam Ansari
2022
Role of Oxidative Stress and Inflammatory Cytokines (TNF-α and IL-6) in Acetic Acid-Induced Ulcerative Colitis in Rats: Ameliorated by Otostegia fruticosa
2021
Evaluation of antidiabetic and hypolipidemic activity of Barleria cristata Linn. leaves in alloxan-induced diabetic rats
2021
Dysregulation of Multiple Signaling Neurodevelopmental Pathways during Embryogenesis: A Possible Cause of Autism Spectrum Disorder
2021
Improving the Solubilization and Bioavailability of Arbidol Hydrochloride by the Preparation of Binary and Ternary β-Cyclodextrin Complexes with Poloxamer 188
2021
Effects of Essential Oils of Elettaria cardamomum Grown in India and Guatemala on Gram-Negative Bacteria and Gastrointestinal Disorders
2021
Polyunsaturated Fatty Acids Mediated Regulation of Membrane Biochemistry and Tumor Cell Membrane Integrity
2021
In vivo wound-healing and antioxidant activity of aqueous extract of Roylea elegans leaves against physically induced burn model in Wistar albino rats
2021
Development of Sustained Release Baricitinib Loaded Lipid-Polymer Hybrid Nanoparticles with Improved Oral Bioavailability
2021
Red yeast rice mitigates high-fat diet induced-obesity related vascular dysfunction in wistar albino rats.
Mohd. Nazam Ansari
2021
In Silico, Ex Vivo and In Vivo Studies of Roflumilast as a Potential Antidiarrheal and Antispasmodic agent: Inhibition of the PDE-4 Enzyme and Voltage-gated Ca++ ion Channels
2020
Pyrethroid-Induced Organ Toxicity and Anti-Oxidant-Supplemented Amelioration of Toxicity and Organ Damage: The Protective Roles of Ascorbic Acid and α-Tocopherol
2020
Eluxadoline Loaded Solid Lipid Nanoparticles for Improved Colon Targeting in Rat Model of Ulcerative Colitis
2020
Preparation of spray dried amorphous solid dispersion of diosmin in soluplus with improved hepato-renoprotective activity: In vitro anti-oxidant and in-vivo safety studies
2020
Assessment of antidiarrheal, antispasmodic and antimicrobial activities of methanolic seeds extract of Peganum harmala L. (nitrariaceae).
Mohd. Nazam Ansari
2020
Novel ?-coronavirus (SARS-CoV-2): current and future aspects of pharmacological treatments.
Mohd. Nazam Ansari
2020
Teratogenic effect of chlorpyrifos and glyphosate on pregnant rats: biochemical and morphological evaluations.
Mohd. Nazam Ansari
2020
Role of inflammatory markers in corona virus disease (COVID-19) patients: a review.
Mohd. Nazam Ansari
2020
Formulation, characterization, in vitro and in vivo evaluations of self-nanoemulsifying drug delivery system of luteolin.
Mohd. Nazam Ansari
2020
Effect of roflumilast in airways disorders via dual inhibition of phosphodiesterase and Ca2+-channel.
Mohd. Nazam Ansari
2020
The potential cardioprotective effect of Matricaria chamomilla extract against diabetes-induced oxidative stress in rats.
Mohd. Nazam Ansari
2020
Cerebral palsy: aetiology, pathophysiology and therapeutic interventions.
Mohd. Nazam Ansari
2020
Roflumilast counteracts dmh-induced preneoplastic colon damage in albino wistar rats.
Mohd. Nazam Ansari
2020
Brucine prevents DMH induced colon carcinogenesis in wistar rats.
Mohd. Nazam Ansari
2020
Evaluation of bronchodialatory and antimicrobial activities of Otostegia fruticosa: A multi-mechanistic approach.
Mohd. Nazam Ansari
2020
Evaluation of α-linolenic acid-based intramammary nanosuspension for treatment of subclinical mastitis.
Mohd. Nazam Ansari
2020
Alpha-linolenic acid based nano-suspension protect against lipopolysaccharides induced mastitis by inhibiting NFκBp65, HIF-1α, and mitochondria-mediated apoptotic pathway in albino Wistar rats
2019
Activation of prolyl hydroxylase‐2 for stabilization of mitochondrial stress along with simultaneous downregulation of HIF‐1α/FASN in ER+ breast cancer subtype.
Mohd. Nazam Ansari
2019
PHD-2 activation: A novel strategy to control HIF-1α and mitochondrial stress to modulate mammary gland pathophysiology in ER+ subtype.
Mohd. Nazam Ansari
2019
Roflumilast, a phosphodiesterase 4 inhibitor, attenuates cadmium-induced renal toxicity via modulation of NF-κB activation and induction of NQO1 in rats.
Mohd. Nazam Ansari
2019
Moringa oleifera Lam. (family Moringaceae) leaf extract attenuates high-fat diet-induced dyslipidemia and vascular endothelium dysfunction in Wistar albino rats.
Mohd. Nazam Ansari
2019
Protective role of Roflumilast against cadmium-induced cardiotoxicity through inhibition of oxidative stress and NF-κB signaling in rats.
Mohd. Nazam Ansari
2019
Comparative study of subchronic toxicities of mosquito repellents (coils, mats and liquids) on vital organs in Swiss albino mice.
Mohd. Nazam Ansari
2019
Prolyl hydroxylase 2: A promising target to inhibit hypoxia-induced cellular metabolism in cancer cells.
Mohd. Nazam Ansari
2018
Modulation of oxidative stress response by flaxseed oil: Role of lipid peroxidation and underlying mechanisms.
Mohd. Nazam Ansari
2018
Revisiting the systemic lipopolysaccharide mediated neuroinflammation: Appraising the effect of L-cysteine mediated hydrogen sulphide on it.
Mohd. Nazam Ansari
2018
Effects of phenidone (DuCLOX-2/5 inhibitor) against N-methyl-N-nitrosourea induced mammary gland carcinoma in albino rats.
Mohd. Nazam Ansari
2018
Effect of early natal supplementation of paracetamol on attenuation of exotoxin/endotoxin induced pyrexia and precipitation of autistic like features in albino rats.
Mohd. Nazam Ansari
2018
Spectroscopic and molecular modeling studies of binding interaction between bovine serum albumin and roflumilast.
Mohd. Nazam Ansari
2018
Evaluation of the diuretic potentials of naringenin in hypercholesterolemic rats.
Mohd. Nazam Ansari
2018
Apremilast prevent doxorubicin-induced apoptosis and inflammation in heart through inhibition of oxidative stress mediated activation of NF-κB signaling pathways.
Mohd. Nazam Ansari
2018
GLA supplementation regulates PHD2 mediated hypoxia and mitochondrial apoptosis in DMBA induced mammary gland carcinoma.
Mohd. Nazam Ansari
2018
Cardioprotective and nephroprotective actions of methanolic extract of Pulicaria somalensis herbs against carbon tetrachloride induced toxicity in rats.
Mohd. Nazam Ansari
2018
Protective role of aerial parts of Silene villosa alcoholic extract against CCl4-induced cardiac and renal toxicity in rats.
Mohd. Nazam Ansari
2018
Phytochemical screening and in-silico investigation of crocin and safranal, constituents of saffron for their cytochrome P450 2C9 enzyme activity.
Mohd. Nazam Ansari
2017
DuCLOX-2/5 inhibition: A promising target for cancer 3 chemoprevention.
Mohd. Nazam Ansari
2017
Comparative efficacy of alpha-linolenic acid and gamma-linolenic acid to attenuate valproic acid-induced autism-like features.
Mohd. Nazam Ansari
2017
Alpha-linolenic acid stabilizes HIF-1 α and downregulates FASN to promote mitochondrial apoptosis for mammary gland chemoprevention.
Mohd. Nazam Ansari
2017
Redefining the role of peripheral LPS as a neuroinflammatory agent and evaluating the role of hydrogen sulphide through metformin intervention.
Mohd. Nazam Ansari
2016
α-Chymotrypsin regulates free fatty acids and UCHL-1 to ameliorate N-methyl nitrosourea induced mammary gland carcinoma in albino wistar rats.
Mohd. Nazam Ansari
2016
The potential anti-inflammatory and wound healing activities of Chitosan in rats.
Mohd. Nazam Ansari
2016
Evaluation of the diuretic and urinary electrolyte effects of methanolic extract of Peganum harmala L. in Wistar albino rats.
Mohd. Nazam Ansari
2016
Experimental models for autistic spectrum disorder-follow up for the validity.
Mohd. Nazam Ansari
2016
Palonosetron attenuates 1, 2-dimethyl hydrazine induced preneoplastic colon damage through downregulating acetylcholinesterase expression and up-regulating synaptic acetylcholine concentration.
Mohd. Nazam Ansari
2016
Protective effects of two Astragalus species on ulcerative colitis in rats.
Mohd. Nazam Ansari
2016
Apremilast reversed carfilzomib-induced cardiotoxicity through inhibition of oxidative stress, NF-κB and MAPK signaling in rats.
Mohd. Nazam Ansari
2016
Enhanced oral bioavailability of insulin-loaded solid lipid nanoparticles: Pharmacokinetic bioavailability of insulin-loaded solid lipid nanoparticles in diabetic rats.
Mohd. Nazam Ansari
2016
Development and evaluation of PLGA polymer based nanoparticles of quercetin.
Mohd. Nazam Ansari
2016
Ameliorative effect of Rumex pictus extract on paracetamol induced hepatotoxicity in rats.
Mohd. Nazam Ansari
2015
The potential anti-inflammatory activity of essential oils of Pituranthos triradiatus and Anthemis deserti in rats.
Mohd. Nazam Ansari
2015
Ameliorative effect of methanol extract of Rumex vesicarius on CCl4-induced liver damage in Wistar albino rats.
Mohd. Nazam Ansari
2015
Evaluation of diuretic activity of methanolic extracts of mustard species in normal mice.
Mohd. Nazam Ansari
2015
Influence of dietary rocket leaveson diuresis and urinary electrolytes excretion in high fat diet-induced obese rats.
Mohd. Nazam Ansari
2015
Synthesis, analgesic, anti-inflammatory and anti-ulcerogenic activities of certain novel Schiff's bases as fenamate isosteres.
Mohd. Nazam Ansari
2015
Ameliorative effect of Eruca sativa extracts on glucose and urinary volume in streptozotocin-induced diabetic rats.
Mohd. Nazam Ansari
2014
Protective role of Eruca sativa extract against testicular damage in streptozotocin-diabetic rats.
Mohd. Nazam Ansari
2014
Antioxidant potential of Rumex vesicarius L.: In vitro approach.
Mohd. Nazam Ansari
2014
Ameliorative effect of rocket leaves on fertility in streptozotocin-induced diabetic rats.
Mohd. Nazam Ansari
2014
Effect of Atriplexfarinosa, Atriplexnummularia and Ficusingenson ulcerative colitis in rats.
Mohd. Nazam Ansari
2013
Anti-oxidant potential of Achyranthes aspera L.: In-vitro approach.
Mohd. Nazam Ansari
2013
Inclusion complex of solid state aspirin with fulvic acid: dissolution, permeability, stability and preliminary pharmacological studies.
Mohd. Nazam Ansari
2013
Oral dose of citrus peel extracts promotes wound repair in diabetic rats.
Mohd. Nazam Ansari
2013
Effect of Beta vulgaris L. on cholesterol rich diet-induced hypercholesterolemia in rats.
Mohd. Nazam Ansari
2011
Attenuation of ischemia reperfusion-induced myocardial injuries by aqueous Embelia ribes Burm. extract in albino rats.
Mohd. Nazam Ansari
2011
Effect of ethanol extract of Embelia ribes fruits on cardiac changes in rats subjected to ischemic reperfusion injury.
Mohd. Nazam Ansari
2009
Effect of folic acid on hematological changes in methionine-induced hyperhomocysteinemia in rats.
Mohd. Nazam Ansari
2009
Ameliorative effect of an ethanol extract of Embelia ribes fruits on isoproterenol-induced cardiotoxicity in diabetic rats.
Mohd. Nazam Ansari
2009
Effect of an ethanol extract of Embelia ribes fruits on isoproterenol-induced myocardial infarction in albino rats.
Mohd. Nazam Ansari
2008
Cardioprotective effect of aqueous extract of Embelia ribes Burm fruits against isoproterenol-induced myocardial infarction in albino rats.
Mohd. Nazam Ansari
2008
Antihyperhomocysteinemic activity of an ethanol extract from Embelia ribes. in albino rats.
Mohd. Nazam Ansari
2008
Cardioprotective activity of zingiber officinale roscoe in rats.
Mohd. Nazam Ansari
2008
Evaluation of antioxidant and neuroprotective effect of ethanolic extract of Embelia ribes Burm in focal cerebral ischemia/reperfusion-induced oxidative stress in rats.
Mohd. Nazam Ansari
2008
Protective effect of Embelia ribes burm on methionine-induced hyperhomocysteinemia and oxidative stress in rat brain.
Mohd. Nazam Ansari
2008
Beneficial effect of Embelia ribes ethanolic extract on blood pressure and glycosylated hemoglobin in streptozotocin-induced diabetes in rats.
Mohd. Nazam Ansari
2008
Potent antihyperglycaemic activity of the aqueous extract of Embelia ribes in streptozotocin-induced diabetic rats.
Mohd. Nazam Ansari
2008
Effect of rosuvastatin on methionine-induced hyperhomocysteinaemia and haematological changes in rats.
Mohd. Nazam Ansari
2008
The effect of aqueous extract of Embelia ribes burm on serum homocysteine, lipids and oxidative enzymes in methionine induced hyperhomocysteinemia.
Mohd. Nazam Ansari
2008
Protective effect of aqueous extract of Embelia ribes burm fruits in middle cerebral artery occlusion-induced focal cerebral ischemia in rats.
Mohd. Nazam Ansari
2008
High performance thin layer chromatographic method for quantification of embelin from embelia ribes burm fruits.
Mohd. Nazam Ansari
2008
Modulatory effect of curcumin on methionine-induced hyperlipidemia and hyperhomocysteinemia in albino rats.
Mohd. Nazam Ansari
2008
Protective role of curcumin in myocardial oxidative damage induced by isoproterenol in rats.
Mohd. Nazam Ansari
2007
Ethanolic zingiber officinale R. Extract pretreatment alleviates isoproternol-induced oxidative myocardial necrosis in rats.
Mohd. Nazam Ansari
2006