Education
Academic Background-
Ph.D. Saint Louis University, USA Biochemistry | Completed: 2008
Publications (213)
Selected Scholarly Contributions
2017
Anti-vascular inflammatory effects of pentacyclic triterpenoids from Astilbe rivularis in vitro and in vivo.
Jong-Sup Bae
2017
Suppressive effects of pelargonidin on PolyPhosphate-mediated vascular inflammatory responses.
Jong-Sup Bae
2017
Suppressive effects of dabrafenib on endothelial protein C receptor shedding.
Jong-Sup Bae
2017
Anti-inflammatory effects of pelargonidin on TGFBIp-induced responses.
Jong-Sup Bae
2017
Endothelial STAT3 activation increases vascular leakage through downregulating tight junction proteins: Implications for diabetic retinopathy.
Jong-Sup Bae
2017
Inhibition of platelet aggregation and thrombosis by indole alkaloids isolated from the edible insect Protaetia brevitarsis seulensis (Kolbe).
Jong-Sup Bae
2017
2017
Anti-factor Xa activities of zingerone with anti-platelet aggregation activity.
Jong-Sup Bae
2017
Suppressive effects of polyozellin on endothelial protein C receptor shedding via inhibiting TACE activity and MAP kinases.
Jong-Sup Bae
2016
Solid-phase synthesis of 1,3,7,8-tetrasubstituted xanthine derivatives on traceless solid support.
Jong-Sup Bae
2016
Inhibitory effect of polyozellin on secretory group IIA phospholipase A2.
Jong-Sup Bae
2016
Anti-inflammatory effects of vicenin-2 and scolymoside on polyphosphate-mediated vascular inflammatory responses.
Jong-Sup Bae
2016
Vicenin-2 and scolymoside inhibit high-glucose-induced vascular inflammation in vitro and in vivo.
Jong-Sup Bae
2016
Trimeric PEG-conjugated Exendin-4 for the treatment of sepsis.
Jong-Sup Bae
2016
Antithrombotic and antiplatelet activities of pelargonidin in vivo and in vitro.
Jong-Sup Bae
2016
Suppressive effects of polyozellin on TGFBIp-mediated septic responses in human endothelial cells and mice.
Jong-Sup Bae
2016
Three diketopiperazines from marine-derived bacteria inhibit LPS-induced endothelial inflammatory responses.
Jong-Sup Bae
2016
Anti-septic effects of dabrafenib on HMGB1-mediated inflammatory responses.
Jong-Sup Bae
2016
Suppressive effects of lysozyme on polyphosphate-mediated vascular inflammatory responses.
Jong-Sup Bae
2016
Ameliorative effect of a rarely occurring C-methylrotenoid on HMGB1-induced septic responses in vitro and in vivo.
Jong-Sup Bae
2016
Suppressive effects of three diketopiperazines from marine-derived bacteria on TGFBIp-mediated septic responses in human endothelial cells and mice.
Jong-Sup Bae
2016
Suppressive effects of pelargonidin on endothelial protein C receptor shedding via the inhibition of TACE activity and MAP kinases.
Jong-Sup Bae
2016
Inhibitory effects of pentacyclic triterpenoids from Astilbe rivularis on TGFBIp-induced inflammatory responses in vitro and in vivo.
Jong-Sup Bae
2016
Anti-inflammatory effects of dabrafenib on polyphosphate-mediated vascular disruption.
Jong-Sup Bae
2016
Inhibitory effects of three diketopiperazines from marine-derived bacteria on endothelial protein C receptor shedding in human endothelial cells and mice.
Jong-Sup Bae
2016
Suppressive effects of three diketopiperazines from marine-derived bacteria on polyphosphate-mediated septic responses.
Jong-Sup Bae
2016
Inhibitory effect of three diketopiperazines from marine-derived bacteria on HMGB1-induced septic responses in vitro and in vivo.
Jong-Sup Bae
2016
Suppressive effects of methylthiouracil on polyphosphate-mediated vascular inflammatory responses.
Jong-Sup Bae
2016
Anti-septic effects of pelargonidin on HMGB1-induced responses in vitro and in vivo.
Jong-Sup Bae
2016
Dabrafenib, as a novel insight into drug repositioning against Secretory Group IIA phospholipase A2.
Jong-Sup Bae
2016
PEGylated lysozymes with anti-septic effects in human endothelial cells and in mice.
Jong-Sup Bae
2015
Quinic acid derivatives from Salicornia herbacea alleviate HMGB1-mediated endothelial dysfunction.
Jong-Sup Bae
2015
Efficient solid-phase synthesis of 2,4-disubstituted 5-carbamoyl-thiazole derivatives using a traceless support.
Jong-Sup Bae
2015
Inhibitory effect of FXa on secretory group IIA phospholipase A2.
Jong-Sup Bae
2015
Anti-septic effects of phenolic glycosides from Rhododendron brachycarpum in vitro and in vivo.
Jong-Sup Bae
2015
Antithrombotic activities of aspalathin and nothofagin via inhibiting platelet aggregation and FIIa/FXa.
Jong-Sup Bae
2015
The histone methyltransferase inhibitor BIX01294 inhibits HIF-1α stability and angiogenesis.
Jong-Sup Bae
2015
Antithrombotic and antiplatelet activities of orientin in vitro and in vivo.
Jong-Sup Bae
2015
Anti-inflammatory effects of aspalathin and nothofagin from rooibos (Aspalathus linearis) in vitro and in vivo.
Jong-Sup Bae
2015
Inhibitory effect of orientin on secretory group IIA phospholipase A2.
Jong-Sup Bae
2015
Anti-septic effects of new 3’-N-substituted carbazole derivatives in vitro and in vivo.
Jong-Sup Bae
2015
Role of moesin in HMGB1-stimulated severe inflammatory responses.
Jong-Sup Bae
2015
Antiseptic effect of vicenin-2 and scolymoside from Cyclopia subternata (Honeybush) in response to HMGB1 as a late sepsis mediator in vitro and in vivo.
Jong-Sup Bae
2015
Ameliorative effect of methylthiouracil on TGFBIp-induced septic responses.
Jong-Sup Bae
2015
2015
Inhibitory effects of polyozellin from Polyozellus multiplex on HMGB1-mediated septic responses.
Jong-Sup Bae
2015
Ameliorative effect of aspalathin and nothofagin from rooibos (Aspalathus linearis) on HMGB1-induced septic responses in vitro and in vivo.
Jong-Sup Bae
2015
Baicalin, baicalein and wogonin inhibits high glucose-induced vascular inflammation in vitro and in vivo.
Jong-Sup Bae
2015
Characterization of ticlopidine-induced developmental and teratogenic defects in Xenopus embryos and human endothelial cells.
Jong-Sup Bae
2015
Vascular barrier protective effects of 3-N-or 3-O-cinnamoyl carbazole derivatives.
Jong-Sup Bae
2015
Anti-inflammatory effects of lysozyme against HMGB1 in human endothelial cells and in mice.
Jong-Sup Bae
2015
Inhibitory effect of vicenin-2 and scolymoside on secretory group IIA phospholipase A2.
Jong-Sup Bae
2015
The role of thioredoxin reductase and glutathione reductase in plumbagin-induced, reactive oxygen species-mediated apoptosis in cancer cell lines.
Jong-Sup Bae
2015
Antitcoagulant and antiplatelet activities of scolymoside.
Jong-Sup Bae
2015
Inhibitory effect of baicalin, baicalein and wogonin on secretory group IIA phospholipase A2.
Jong-Sup Bae
2015
Anti-inflammatory effects of methylthiouracil in vitro and in vivo.
Jong-Sup Bae
2015
Efficient syntheses of 1,2,3-triazoloamide derivatives using solid-and solution-phase synthetic approaches.
Jong-Sup Bae
2015
A double‐chambered protein nanocage loaded with thrombin receptor agonist peptide (TRAP) and γ‐carboxyglutamic acid of protein C (PC‐Gla) for sepsis treatment.
Jong-Sup Bae
2015
Caffeoyl glucosides from Nandina domestica inhibit LPS-induced endothelial inflammatory responses.
Jong-Sup Bae
2015
Flavanones and chromones from Salicornia herbacea mitigate septic lethality via restoration of vascular barrier integrity.
Jong-Sup Bae
2015
Inhibitory effects of lysozyme on endothelial protein C 1receptor shedding in vitro and in vivo.
Jong-Sup Bae
2015
Anti-inflammatory effects of vicenin-2 and scolymoside in vitro and in vivo.
Jong-Sup Bae
2015
Ameliorative effect of vicenin-2 and olymoside on TGFBIp-induced septic responses.
Jong-Sup Bae
2015
Potential therapeutic properties of natural products through the expression of heme oxygenase-1.
Jong-Sup Bae
2015
In‐depth proteomics approach of secretome to identify novel biomarker for sepsis in LPS‐stimulated endothelial cells.
Jong-Sup Bae
2015
Aspalathin and nothofagin from rooibos (Aspalathus linearis) inhibit endothelial protein C receptor shedding in vitro and in vivo.
Jong-Sup Bae
2015
Beneficial effect of persimmon leaves and bioactive compounds on thrombosis.
Jong-Sup Bae
2015
Anti-inflammatory effects of Baicalin, Baicalein and Wogonin in vitro and in vivo.
Jong-Sup Bae
2015
Early diagnosis of sepsis using serum hemoglobin subunit Beta.
Jong-Sup Bae
2015
Aspalathin and nothofagin from rooibos (Aspalathus linearis) inhibits high glucose-induced inflammation in vitro and in vivo.
Jong-Sup Bae
2015
Protective effect of butylated hydroxylanisole against hydrogen peroxide-induced apoptosis in primary cultured mouse hepatocytes.
Jong-Sup Bae
2015
A group of novel HIF‐1α inhibitors, glyceollins, blocks HIF‐1α synthesis and decreases its stability via inhibition of the PI3K/AKT/mTOR pathway and Hsp90 binding.
Jong-Sup Bae
2015
Anti-inflammatory effects of hyperoside in human endothelial cells and in mice.
Jong-Sup Bae
2015
Inhibitory effect of exendin-4 on secretory group IIA phospholipase A2.
Jong-Sup Bae
2015
Antiplatelet, anticoagulant and profibrinolytic activities of baicalin.
Jong-Sup Bae
2015
Novel insight into drug repositioning: Methylthiouracil as a case in point.
Jong-Sup Bae
2015
Anti-septic effects of glyceollins in HMGB1-induced inflammatory responses in vitro and in vivo.
Jong-Sup Bae
2014
Vascular barrier protective effects of pellitorine in LPS-induced inflammation in vitro and in vivo.
Jong-Sup Bae
2014
Cudratricusxanthone A inhibits endothelial protein C receptor shedding in vitro and in vivo.
Jong-Sup Bae
2014
Anti-inflammatory effects of rutin on HMGB1-induced inflammatory responses in vitro and in vivo.
Jong-Sup Bae
2014
Antiplatelet, anticoagulant and profibrinolytic activities of withaferin A.
Jong-Sup Bae
2014
A comparison of the in vitro inhibitory effects of thelephoric acid and SKF-525A on human cytochrome P450 activity.
Jong-Sup Bae
2014
Emodin-6-O-β-D--glucoside inhibits high-glucose-induced vascular inflammation.
Jong-Sup Bae
2014
Anti-septic effects of pellitorine in HMGB1-induced inflammatory responses in vitro and in vivo.
Jong-Sup Bae
2014
Piperlonguminine downregulates endothelial protein C receptor shedding in vitro and in vivo.
Jong-Sup Bae
2014
Endocan elicits severe vascular inflammatory responses in vitro and in vivo.
Jong-Sup Bae
2014
Transforming growth factor β-induced protein promotes severe vascular inflammatory responses.
Jong-Sup Bae
2014
Vascular barrier protective effects of piperlonguminine in vitro and in vivo.
Jong-Sup Bae
2014
Exendin-4 inhibits endothelial protein C receptor shedding in vitro and in vivo.
Jong-Sup Bae
2014
Andrographolide inhibits HMGB1‐induced inflammatory responses in human umbilical vein endothelial cells and in murine polymicrobial sepsis.
Jong-Sup Bae
2014
Antithrombotic activities of oroxylin A in vitro and in vivo.
Jong-Sup Bae
2014
Thymosin beta4 regulates cardiac valve formation via endothelial-mesenchymal transformation in zebrafish embryos.
Jong-Sup Bae
2014
Withaferin A is an inhibitor of endothelial protein C receptor shedding in vitro and in vivo.
Jong-Sup Bae
2014
The first cyclomegastigmane rhododendroside A from Rhododendron brachycarpum alleviates HMGB1-induced sepsis.
Jong-Sup Bae
2014
2014
Antiplatelet activities of hyperoside in vitro and in vivo.
Jong-Sup Bae
2014
Vascular barrier protective effects of orientin and isoorientin in LPS-induced inflammation in vitro and in vivo.
Jong-Sup Bae
2014
Pick1 modulates ephrinB1-induced junctional disassembly through an association with ephrinB1.
Jong-Sup Bae
2014
Antiplatelet and antithrombotic activities of purpurogallin in vitro and in vivo.
Jong-Sup Bae
2014
Identification of Metabolites of N-(5-Benzoyl-2-(4-(2-Methoxyphenyl) piperazin-1-yl)thiazol-4-yl) pivalamide including CYP3A4-Mediated C-demethylation in human liver microsomes with high-resolution/high-accuracy tandem mass.
Jong-Sup Bae
2014
In vitro inhibitory effect of piperlonguminine isolated from Piper longum on human cytochrome P450 1A2.
Jong-Sup Bae
2014
Antiplatelet, anticoagulant, and profibrinolytic activities of cudratricusxanthone A.
Jong-Sup Bae
2014
Fisetin inhibits high-glucose-induced vascular inflammation in vitro and in vivo.
Jong-Sup Bae
2014
Anti-inflammatory effects of triterpenoids: Naturally occurring and synthetic agents.
Jong-Sup Bae
2014
Antithrombotic activities of wogonin and wogonoside via inhibiting platelet aggregation.
Jong-Sup Bae
2014
Hyperoside inhibits high-glucose-induced vascular inflammation in vitro and in vivo.
Jong-Sup Bae
2014
Inhibitory effects of rutin on the endothelial protein C receptor shedding in vitro and in vivo.
Jong-Sup Bae
2014
2014
Orientin inhibits HMGB1-induced inflammatory responses in HUVECs and in murine polymicrobial sepsis.
Jong-Sup Bae
2014
Exendin-4 inhibits HMGB1-induced inflammatory responses in HUVECs and in murine polymicrobial sepsis.
Jong-Sup Bae
2014
Ginsenosides Inhibit HMGB1-induced Inflammatory Responses in HUVECs and in murine polymicrobial sepsis.
Jong-Sup Bae
2014
Factor Xa inhibits HMGB1-induced septic responses in human umbilical vein endothelial cells and in mice.
Jong-Sup Bae
2014
Sulforaphane inhibits endothelial protein C receptor shedding in vitro and in vivo.
Jong-Sup Bae
2014
Vascular barrier protective effects of baicalin, baicalein and wogonin in vitro and in vivo.
Jong-Sup Bae
2014
Orientin inhibits high glucose-induced vascular inflammation in vitro and in vivo.
Jong-Sup Bae
2014
Anti‐transforming growth factor β‐induced protein antibody ameliorates vascular barrier dysfunction and improves survival in sepsis.
Jong-Sup Bae
2014
Endocan as a potential diagnostic or prognostic biomarker for chronic kidney disease.
Jong-Sup Bae
2014
Inhibitory effects of oroxylin a on endothelial protein c receptor shedding in vitro and in vivo.
Jong-Sup Bae
2014
Antithrombotic activities of sulforaphane via inhibiting platelet aggregation and FIIa/FXa.
Jong-Sup Bae
2014
Effects of lycopene on endothelial protein C receptor shedding in vitro and in vivo.
Jong-Sup Bae
2013
Anticoagulant and antiplatelet activities of Artemisia princeps Pampanini and its bioactive components.
Jong-Sup Bae
2013
Emodin-6-O-β-d-glucoside inhibits HMGB1-induced inflammatory responses in vitro and in vivo.
Jong-Sup Bae
2013
Anti‐inflammatory activities of isorhamnetin‐3‐O‐galactoside against HMGB1‐induced inflammatory responses in both HUVECs and CLP‐induced septic mice.
Jong-Sup Bae
2013
Anti-inflammatory effects of oleanolic acid on LPS-induced inflammation in vitro and in vivo.
Jong-Sup Bae
2013
Antithrombotic and profibrinolytic activities of isorhamnetin-3-O-galactoside and hyperoside.
Jong-Sup Bae
2013
Inhibitory effects of epi-sesamin on HMGB1-induced vascular barrier disruptive responses in vitro and in vivo.
Jong-Sup Bae
2013
Persicarin is anti‐inflammatory mediator against HMGB1‐induced inflammatory responses in HUVECs and in CLP‐induced sepsis mice.
Jong-Sup Bae
2013
2013
Barrier protective effects of rosmarinic acid on HMGB1‐induced inflammatory responses in vitro and in vivo.
Jong-Sup Bae
2013
Concentration dependent anti-inflammatory effects thrombin on polyphosphate-mediated inflammatory responses in vitro and in vivo.
Jong-Sup Bae
2013
Down-regulation of endothelial protein C receptor shedding by persicarin and isorhamnetin-3-O-galactoside.
Jong-Sup Bae
2013
Barrier protective effects of piperlonguminine in LPS-induced inflammation in vitro and in vivo.
Jong-Sup Bae
2013
An efficient and regioselective synthesis of 2, 3-disubstituted 6-aminoquinoxaline derivatives using alkoxylation and microwave-assisted sonogashira coupling.
Jong-Sup Bae
2013
Rosmarinic acid down-regulates endothelial protein C receptor shedding in vitro and in vivo.
Jong-Sup Bae
2013
Selective inhibition of the cytochrome P450 isoform by hyperoside and its potent inhibition of CYP2D6.
Jong-Sup Bae
2013
Pancreatic lipase inhibitory gallotannins from galla rhois with inhibitory effects on adipocyte differentiation in 3T3-L1 cells.
Jong-Sup Bae
2013
Emodin-6-O-β-d-glucoside down-regulates endothelial protein C receptor shedding.
Jong-Sup Bae
2013
Inhibitory effects of epi-sesamin on endothelial protein C receptor shedding in vitro and in vivo.
Jong-Sup Bae
2013
Inhibitory effect of glyceollins on vasculogenesis through suppression of endothelial progenitor cell function.
Jong-Sup Bae
2013
Inhibitory effects of purpurogallin on the endothelial protein C receptor shedding in vitro and in vivo.
Jong-Sup Bae
2013
In vivo evaluation and comparison of developmental toxicity and teratogenicity of perfluoroalkyl compounds using Xenopus embryos.
Jong-Sup Bae
2013
Anticoagulant activities of piperlonguminine in vitro and in vivo.
Jong-Sup Bae
2013
Antithrombotic activities of epi-sesamin in vitro and in vivo.
Jong-Sup Bae
2013
Thrombin inhibits HMGB1-mediated proinflammatory signaling responses when endothelial protein C receptor is occupied by its natural ligand.
Jong-Sup Bae
2013
Antithrombotic activities of pellitorine in vitro and in vivo.
Jong-Sup Bae
2013
Inhibitory effects of lycopene on the expression of pro-inflammatory genes in human vascular endothelial cells.
Jong-Sup Bae
2012
Effect of Activated Protein C (APC) on apoptosis of cancer cells.
Jong-Sup Bae
2012
Evaluation of acetylcholinesterase inhibitory and antioxidative activities of Rhus javanica.
Jong-Sup Bae
2012
Anticoagulant activities of oleanolic acid via inhibition of tissue factor expressions.
Jong-Sup Bae
2012
2012
Barrier protective effects of rutin in LPS-induced inflammation in vitro and in vivo.
Jong-Sup Bae
2012
Role of high mobility group box 1 in inflammatory disease: Focus on sepsis.
Jong-Sup Bae
2012
Enzymatic transformation of caffeic acid with enhanced cyclooxygenase-2 inhibitory activity.
Jong-Sup Bae
2012
Inhibitory effects of kaempferol-3-O-sophoroside on HMGB1-mediated proinflammatory responses.
Jong-Sup Bae
2012
Anti-inflammatory effects of kaempferol-3-O-sophoroside in human endothelial cells.
Jong-Sup Bae
2012
Anti-inflammatory functions of purpurogallin in LPS-activated human endothelial cells.
Jong-Sup Bae
2012
2012
Effects of (-)-epigallocatechin gallate on HMGB1 and interleukin-1β-mediated barrier disruption in human endothelial cells.
Jong-Sup Bae
2012
Anti-inflammatory activities of oleanolic acid on HMGB1 activated HUVECs.
Jong-Sup Bae
2012
Barrier protective activities of curcumin and its derivative.
Jong-Sup Bae
2012
Inhibitory effects of lycopene on HMGB1-mediated pro-inflammatory responses in both cellular and animal models.
Jong-Sup Bae
2012
Barrier protective activities of phloroglucinol on lipopolysaccharide (LPS)-induced barrier disruption in human endothelial cells.
Jong-Sup Bae
2012
Vascular barrier protective effects of phlorotannins on HMGB1-mediated proinflammatory responses in vitro and in vivo.
Jong-Sup Bae
2012
Vascular barrier protective effects of eckol and its derivatives.
Jong-Sup Bae
2012
Effects of lower concentration thrombin on high-mobility group box 1 protein-mediated inflammatory responses.
Jong-Sup Bae
2012
Polyphosphate elicits pro-inflammatory responses that are counteracted by activated protein C in both cellular and animal models.
Jong-Sup Bae
2012
Barrier protective effects of withaferin A in HMGB1-induced inflammatory responses in both cellular and animal models.
Jong-Sup Bae
2012
Pancreatic lipase inhibitory and antioxidant activities of Zingiber officinale extracts.
Jong-Sup Bae
2011
Antithrombotic and profibrinolytic activities of phloroglucinol.
Jong-Sup Bae
2011
Barrier protective effects of lycopene in human endothelial cells.
Jong-Sup Bae
2011
Inhibitory effect of thrombin on the expression of secretory group IIA phospholipase A2.
Jong-Sup Bae
2011
Polyphenolic constituents from the aerial parts of Thymus quinquecostatus var. japonica collected on Ulleung Island.
Jong-Sup Bae
2011
Vascular anti-inflammatory effects of curcumin on HMGB1-mediated responses in vitro.
Jong-Sup Bae
2011
Activated protein c inhibits high mobility group box 1 signaling in endothelial cells.
Jong-Sup Bae
2011
Effect of thrombin on the TNF-α induced IL-6 production in HUVECs.
Jong-Sup Bae
2010
Concentration of heavy metals in granule, globular and liquid types of herbal medicines.
Jong-Sup Bae
2010
A study on the concentration of aflatoxin B1 in granule and globular types of herbal medicines.
Jong-Sup Bae
2010
5α-reductase inhibitory components as antiandrogens from herbal medicine.
Jong-Sup Bae
2010
Pancreatic lipase inhibitors isolated from the leaves of cultivated mountain ginseng (Panax ginseng).
Jong-Sup Bae
2010
Thrombin and activated protein C inhibit the expression of secretory group IIA phospholipase A2 in the TNF-α-activated endothelial cells by EPCR and PAR-1 dependent mechanisms.
Jong-Sup Bae
2010
Thrombin upregulates the angiopoietin-Tie2 Axis: endothelial protein C receptor occupancy prevents the thrombin mobilization of angiopoietin 2 and P-selectin from Weibel-Palade bodies.
Jong-Sup Bae
2010
Ecklonia cava extracts inhibit lipopolysaccharide induced inflammatory responses in human endothelial cells.
Jong-Sup Bae
2010
Inhibitory effects of antithrombin on the expression of secretory group IIA phospholipase A2 in endothelial cells.
Jong-Sup Bae
2010
Thrombin down-regulates the TGF-β-mediated synthesis of collagen and fibronectin by human proximal tubule epithelial cells through the EPCR-dependent activation of PAR-1.
Jong-Sup Bae
2010
Factor X/Xa elicits protective signaling responses in endothelial cells directly via PAR-2 and indirectly via endothelial protein C receptor-dependent recruitment of PAR-1.
Jong-Sup Bae
2010
Effect of soluble EPCR on the anti-inflammatory effects by activated protein C.
Jong-Sup Bae
2009
Quantitative analysis of carotenoids in carrot cultivars produced in Korea.
Jong-Sup Bae
2009
Acetylcholinesterase inhibitory and antioxidant properties of Aster yomena extract.
Jong-Sup Bae
2009
Specific residues of RUNX2 are obligatory for formation of BMP2-induced RUNX2-SMAD complex to promote osteoblast differentiation.
Jong-Sup Bae
2009
Thrombin inhibits nuclear factor κB and RhoA pathways in cytokine-stimulated vascular endothelial cells when EPCR is occupied by protein C.
Jong-Sup Bae
2009
Mutagenesis studies toward understanding the intracellular signaling mechanism of antithrombin.
Jong-Sup Bae
2009
Concentration dependent dual effect of thrombin in endothelial cells via Par-1 and Pi3 kinase.
Jong-Sup Bae
2009
Ixolaris binding to factor X reveals a precursor state of factor Xa heparin-binding exosite.
Jong-Sup Bae
2008
Structural coupling of Smad and Runx2 for execution of the BMP2 osteogenic signal.
Jong-Sup Bae
2008
Autolysis loop restricts the specificity of activated protein C: Analysis by FRET and functional assays.
Jong-Sup Bae
2008
Lipid raft localization regulates the cleavage specificity of protease activated receptor 1 in endothelial cells.
Jong-Sup Bae
2008
Protease Activated Receptor 1 (PAR-1) activation by thrombin is protective in human pulmonary artery endothelial cells if endothelial protein C receptor is occupied by its natural ligand.
Jong-Sup Bae
2008
Protein Z-dependent protease inhibitor binds to the C-terminal domain of protein Z.
Jong-Sup Bae
2008
Functional properties and active-site topographies of factor X Gla- and prothrombin Gla-domain chimeras of activated protein C.
Jong-Sup Bae
2008
Reconstitution of Runx2/Cbfa1-null cells identifies a requirement for BMP2 signaling through a Runx2 functional domain during osteoblast differentiation.
Jong-Sup Bae
2007
Receptors of the protein C activation and activated protein C signaling pathways are colocalized in lipid rafts of endothelial cells.
Jong-Sup Bae
2007
Engineering a disulfide bond to stabilize the calcium-binding loop of activated protein C eliminates its anticoagulant but not its protective signaling properties.
Jong-Sup Bae
2007
Identification of a specific exosite on activated protein C for interaction with protease-activated receptor 1.
Jong-Sup Bae
2007
The ligand occupancy of endothelial protein C receptor switches the protease-activated receptor 1-dependent signaling specificity of thrombin from a permeability-enhancing to a barrier-protective response in endothelial cells.
Jong-Sup Bae
2007
βig-h3 triggers signaling pathways mediating adhesion and migration of vascular smooth muscle cells through αvβ5 integrin.
Jong-Sup Bae
2006
Beta ig-h3 promotes renal proximal tubular epithelial cell adhesion, migration and proliferation through the interaction with α3β1 integrin.
Jong-Sup Bae
2004
Elevation of urinary βig-h3, transforming growth factor-β-induced protein in patients with type 2 diabetes and nephropathy.
Jong-Sup Bae
2004
Effect and mechanism of high glucose level on the expression of an adhesion protein, βig-h3 and cellular function in endothelial cells.
Jong-Sup Bae
2003
TGF-β-induced protein βig-h3 is upregulated by high glucose in vascular smooth muscle cells.
Jong-Sup Bae
2003
Expression of TGF-β-induced matrix protein βig-h3 is up-regulated in the diabetic rat kidney and human proximal tubular epithelial cells treated with high glucose.
Jong-Sup Bae
2003
Effect of transforming growth factor-induced gene product, βig-h3 on proliferation, migration and adhesion of aortic smooth muscle cells cultured in high glucose.
Jong-Sup Bae
2002
βig-h3 supports keratinocyte adhesion, migration and proliferation through α3β1 integrin.
Jong-Sup Bae
2002