Education
Academic Background-
Ph.D. Khon Kaen University, Thailand Medical Biochemistry | Completed: 2004
Editorial Services
Editorial & Publishing Roles
Editorial Board Member
Serving as Editorial Board Member for International Journal of Cancer Research.
Editorial Board Member
Serving as Editorial Board Member for Research Journal of Parasitology.
Editorial Board Member
Serving as Editorial Board Member for Asian Journal of Scientific Research.
Publications (85)
Selected Scholarly Contributions
Opisthorchis viverrini infection is associated with kidney injury involving excretory–secretory product-mediated inflammation, oxidative stress, and hypoxia
2026
Prolonged Oxidative Stress Drives p53/p21‐Mediated Senescence and Degenerative Adaptation in Kidney‐Derived Cells
2026
Combination of Label-Free SERS-Based Nanosensors and Machine Learning for Diagnosis of Cholangiocarcinoma
2026
System-level multi-omics uncover proteomic, peptidomic, and metabolic remodeling in Microcystin-LR exacerbated chronic kidney disease
2026
Serum β-hCG Combined with Traditional Tumor Markers Improves Detection Efficacy and Prognostic Prediction in Cholangiocarcinoma
2026
Environmental contamination of
Opisthorchis viverrini
eggs and its impact on transmission control in rural northeast Thailand
2025
High-fat/high-fructose diet and Opisthorchis viverrini infection promote metabolic dysfunction-associated steatotic liver disease via inflammation, fibrogenesis, and metabolic dysfunction
2025
Impact of Fermentation on Bacterial and Fungal Microbiome Interactions in
Pla-Ra
, a Traditional Thai Food
2025
Curcumin-Loaded Maltodextrin-Based Proniosomes Potentially Effective against Gemcitabine-Resistant Cholangiocarcinoma
2025
Highly Accurate and Robust Early Stage Detection of Cholangiocarcinoma Using Near-Lossless SERS Signal Processing with Machine Learning and 2D CNN for Point-of-care Mobile Application
2025
One Health integrated strategies for sustainable control of Opisthorchis viverrini infections in rural endemic areas of Thailand
2025
Poly(d,l-lactide-co-glycolide) Nanoparticles Encapsulating Doxorubicin for Improved Treatment in Cholangiocarcinoma and Drug-Resistant Cells
2025
Minimally invasive detection of early-stage opisthorchiasis-associated cholangiocarcinoma using label-free surface-enhanced Raman spectroscopy (SERS) of hamster serum
2025
2025
Transcriptome changes of liver fluke Opisthorchis viverrini in diabetic hamsters
2024
The Effect of a High Monosodium Glutamate Diet in Inducing Changes in Microbiota Diversity and Kidney Pathology in Hamsters Infected with Opisthorchis viverrini
2024
Comparative efficacy of chemical and botanical pediculicides in Thailand and 4% dimeticone against head louse, Pediculus humanus capitis
2023
Strongyloides stercoralis infection reduces Fusicatenibacter and Anaerostipes in the gut and increases bacterial amino-acid metabolism in early-stage chronic kidney disease
2023
Hydroethanolic Cyperus rotundus L. extract exhibits anti-obesity property and increases lifespan expectancy in Drosophila melanogaster fed a high-fat diet
2022
Association of Strongyloides stercoralis infection and type 2 diabetes mellitus in northeastern Thailand: Impact on diabetic complication-related renal biochemical parameters
2022
Strongyloides stercoralis infection induces gut dysbiosis in chronic kidney disease patients
2022
Curcumin-loaded nanocomplexes ameliorate the severity of nonalcoholic steatohepatitis in hamsters infected with Opisthorchis viverrini
2022
Opisthorchis viverrini Infection Induces Metabolic and Fecal Microbial Disturbances in Association with Liver and Kidney Pathologies in Hamsters
2021
An optimized agar plate culture improves diagnostic efficiency for Strongyloides stercoralis infection in an endemic community
2020
Effect of a health education program on reduction of pediculosis in school girls at Amphoe Muang, Khon Kaen Province, Thailand
2018
Co-occurrence of opisthorchiasis and diabetes exacerbates morbidity of the hepatobiliary tract disease
2018
Discovering proteins for chemoprevention and chemotherapy by curcumin in liver fluke infection-induced bile duct cancer
2018
MRI and 1 H MRS evaluation for the serial bile duct changes in hamsters after infection with Opisthorchis viverrini.
Somchai Pinlaor
2013
Annexin A1: A new immunohistological marker of cholangiocarcinoma.
Somchai Pinlaor
2013
Subtype identification of Blastocystis spp. isolated from patients in a major hospital in northeastern Thailand.
Somchai Pinlaor
2013
α-Tocopherol and lipid profiles in plasma and the expression of α-tocopherol-related molecules in the liver of Opisthorchis viverrini-infected hamsters.
Somchai Pinlaor
2013
Melatonin inhibits cholangiocarcinoma and reduces liver injury in Opisthorchis viverrini‐infected and N‐nitrosodimethylamine‐treated hamsters.
Somchai Pinlaor
2013
Alcohol and alkalosis enhance excystation of Opisthorchis viverrini metacercariae.
Somchai Pinlaor
2013
Inflammation-related DNA damage and expression of CD133 and Oct3/4 in cholangiocarcinoma patients with poor prognosis.
Somchai Pinlaor
2013
Down-regulated expression of hsp70 in correlation with clinicopathology of cholangiocarcinoma.
Somchai Pinlaor
2012
Platelet-derived growth factor may be a potential diagnostic and prognostic marker for cholangiocarcinoma.
Somchai Pinlaor
2012
Liver fluke-induced hepatic oxysterols stimulate DNA damage and apoptosis in cultured human cholangiocytes.
Somchai Pinlaor
2012
Specific serum IgG, but not IgA, antibody against purified Opisthorchis viverrini antigen associated with hepatobiliary disease and cholangiocarcinoma.
Somchai Pinlaor
2012
Plasma hydroxyproline, MMP‐7 and collagen I as novel predictive risk markers of hepatobiliary disease‐associated cholangiocarcinoma.
Somchai Pinlaor
2012
The liver fluke Opisthorchis viverrini expresses nitric oxide synthase but not gelatinases.
Somchai Pinlaor
2012
Proteomic analysis to identify plasma orosomucoid 2 and kinesin 18A as potential biomarkers of cholangiocarcinoma.
Somchai Pinlaor
2012
Diagnostic values of parasite-specific antibody detections in saliva and urine in comparison with serum in opisthorchiasis.
Somchai Pinlaor
2012
Proton pump inhibitors suppress iNOS-dependent DNA damage in Barrett's esophagus by increasing Mn-SOD expression.
Somchai Pinlaor
2012
Inflammation-induced protein carbonylation contributes to poor prognosis for cholangiocarcinoma.
Somchai Pinlaor
2012
Alteration of galectin-1 during tumorigenesis of Opisthorchis viverrini infection-induced cholangiocarcinoma and its correlation with clinicopathology.
Somchai Pinlaor
2012
Oxidative and nitrative DNA damage: Key events in opisthorchiasis-induced carcinogenesis.
Somchai Pinlaor
2012
Increased expression of TLR-2, COX-2 and SOD-2 genes in the peripheral blood leukocytes of opisthorchiasis patients induced by Opisthorchis viverrini antigen.
Somchai Pinlaor
2012
Viable metacercariae of Opisthorchis viverrini in northeastern Thai cyprinid fish dishes-as part of a rational program for control of O. viverrini-associated cholangiocarcinoma.
Somchai Pinlaor
2012
Involvement of c-Ski oncoprotein in carcinogenesis of cholangiocacinoma induced by Opisthorchis viverrini and N-nitrosodimethylamine.
Somchai Pinlaor
2011
Curcumin induces a nuclear factor-erythroid 2-related factor 2-driven response against oxidative and nitrative stress after praziquantel treatment in liver fluke-infected hamsters.
Somchai Pinlaor
2011
Curcumin decreases cholangiocarcinogenesis in hamsters by suppressing inflammation‐mediated molecular events related to multistep carcinogenesis.
Somchai Pinlaor
2011
Candidate genes involving in tumorigenesis of cholangiocarcinoma induced by Opisthorchis viverrini infection.
Somchai Pinlaor
2011
Accumulation of miscoding etheno-DNA adducts and highly expressed DNA repair during liver fluke-induced cholangiocarcinogenesis in hamsters.
Somchai Pinlaor
2010
Lipid peroxidation and etheno DNA adducts in white blood cells of liver fluke-infected patients: Protection by plasma α-tocopherol and praziquantel.
Somchai Pinlaor
2010
Proteomic identification of peroxiredoxin 6 for host defence against Opisthorchis viverrini infection.
Somchai Pinlaor
2010
Protective effect of melatonin against Opisthorchis viverrini‐induced oxdative and nitrosative DNA damage and liver injury in hamsters.
Somchai Pinlaor
2010
Reduction of periductal fibrosis in liver fluke-infected hamsters after long-term curcumin treatment.
Somchai Pinlaor
2010
Involvement of MMP‐9 in peribiliary fibrosis and cholangiocarcinogenesis via Rac1‐dependent DNA damage in a hamster model.
Somchai Pinlaor
2010
Tissue invasive macrophage density is correlated with prognosis in cholangiocarcinoma.
Somchai Pinlaor
2010
Circulating CD14+ CD16+ monocyte levels predict tissue invasive character of cholangiocarcinoma.
Somchai Pinlaor
2010
Turmeric reduces inflammatory cells in hamster opisthorchiasis.
Somchai Pinlaor
2009
Alterations of gene expression of RB pathway in Opisthorchis viverrini infection-induced cholangiocarcinoma.
Somchai Pinlaor
2009
Effect of praziquantel treatment on the expression of matrix metalloproteinases in relation to tissue resorption during fibrosis in hamsters with acute and chronic Opisthorchis viverrini infection.
Somchai Pinlaor
2009
Curcumin reduces oxidative and nitrative DNA damage through balancing of oxidant-antioxidant status in hamsters infected with Opisthorchis viverrini.
Somchai Pinlaor
2009
Time profiles of the expression of metalloproteinases, tissue inhibitors of metalloproteases, cytokines and collagens in hamsters infected with Opisthorchis viverrini with special reference to peribiliary fibrosis and liver injury.
Somchai Pinlaor
2009
Apoptosis-related gene expression in hamster opisthorchiasis post praziquantel treatment.
Somchai Pinlaor
2008
High excretion of etheno adducts in liver fluke-infected patients: Protection by praziquantel against DNA damage.
Somchai Pinlaor
2008
Oxidative and nitrative stress in Opisthorchis viverrini-infected hamsters: An indirect effect after praziquantel treatment.
Somchai Pinlaor
2008
Urinary 8-oxo-7, 8-dihydro-2'-deoxyguanosine in patients with parasite infection and effect of antiparasitic drug in relation to cholangiocarcinogenesis.
Somchai Pinlaor
2008
Apoptosis-related gene expressions in hamsters re-infected with Opisthorchis viverrini and re-treated with praziquantel.
Somchai Pinlaor
2007
Oxidative and nitrative DNA damage in animals and patients with inflammatory diseases in relation to inflammation-related carcinogenesis.
Somchai Pinlaor
2006
iNOS-dependent DNA damage via NF-kappaB expression in hamsters infected with Opisthorchis viverrini and its suppression by the antihelminthic drug praziquantel.
Somchai Pinlaor
2006
Nitrative and oxidative DNA damage in oral lichen planus in relation to human oral carcinogenesis.
Somchai Pinlaor
2005
Detection of opportunistic and non-opportunistic intestinal parasites and liver flukes in HIV-positive and HIV-negative subjects.
Somchai Pinlaor
2005
Nitrative and oxidative DNA damage in intrahepatic cholangiocarcinoma patients in relation to tumor invasion.
Somchai Pinlaor
2005
Opisthorchis viverrini antigen induces the expression of Toll-like receptor 2 in macrophage RAW cell line.
Somchai Pinlaor
2005
Accumulation of 8-nitroguanine in human gastric epithelium induced by Helicobacter pylori infection.
Somchai Pinlaor
2004
Mechanism of NO-mediated oxidative and nitrative DNA damage in hamsters infected with Opisthorchis viverrini: A model of inflammation-mediated carcinogenesis.
Somchai Pinlaor
2004
Repeated infection with Opisthorchis viverrini induces accumulation of 8-nitroguanine and 8-oxo-7, 8-dihydro-2'-deoxyguanine in the bile duct of hamsters via inducible nitric oxide synthase.
Somchai Pinlaor
2004
PCR diagnosis of Pneumocystis carinii on sputum and bronchoalveolar lavage samples in immuno-compromised patients.
Somchai Pinlaor
2004
Hepatobiliary changes, antibody response, and alteration of liver enzymes in hamsters re-infected with Opisthorchis viverrini.
Somchai Pinlaor
2004
8-Nitroguanine formation in the liver of hamsters infected with Opisthorchis viverrini.
Somchai Pinlaor
2003
Seroprevalence of specific total immunoglobulin (Ig), IgG and IgM antibodies to Toxoplasma gondii in blood donors from Loei Province, Northeast Thailand.
Somchai Pinlaor
2000
K-ras oncogene and p53 gene mutations in cholangiocarcinoma from Thai patients.
Somchai Pinlaor
1998
Centrocestus formosanus: Surface morphology of metacercaria, adult and egg.
Somchai Pinlaor
1997