About
Professional SummaryDr. Trina Ekawati Tallei is a Professor at Department of Biology, Faculty of Mathematics and Natural Sciences, Sam Ratulangi University. Prof. Tallei has over 50 scientific papers and projects either presented or published. She is internationally recognized in her field of conservation Biology. She is an editor at SAFE Network (Asia Pacific Network For Sustainable Agriculture, Food and Energy). She received a Millinium Development Goals Awards in 2013 in Indonesia.
Education
Academic Background-
Ph.D. Sam Ratulangi University, Indonesia Entomology | Completed: 2010
Publications (117)
Selected Scholarly Contributions
Network pharmacology and molecular docking analysis of propolis-derived bioactive compounds targeting antihypertensive pathways
2026
Global Mapping of Flavonoids in Fruits and Vegetables: Targeting Insulin Receptors,
GLP
‐
1R
, and
PPARs
to Mitigate Diabetes
2026
Superiority of propolis and honey over topical acyclovir for herpes simplex: A meta-analysis
2026
Propolis Reduces Oxidative Stress, Modulates Imd-Dependent Immune Responses, and Improves Survival in a Drosophila melanogaster Autoinflammatory Model
2026
2026
Algal peptides for future food: Key players and multifaceted agents in the fight against cardiometabolic syndrome
2025
Dual anti-inflammatory and antimicrobial effects of stingless bee propolis on second-degree burns
2025
Network Pharmacology-Based Identification of Key Metabolites from Immunized Rhynchophorus Larvae as Therapeutic Agents Against Antibiotic-Resistant Neisseria gonorrhoea
2025
Metabolomic profiling and anti-inflammatory activity of Blumea balsamifera: Insights from in silico and in vitro studies
2025
Efficacy of music listening in alleviating anxiety among college students: A meta-analysis of randomized controlled trials
2025
Comparative Study of DNA Barcoding and Mini-Barcoding based on COI Gene for Species Identification and Phylogeny of Formicidae Family (Insecta: Hymenoptera)
2025
Hydropuntia edulis extract mitigates metabolic dysregulation via DPP-4 inhibition, lipid modulation, and GLP-1/AKT1 pathway activation
2025
SH003 as a Redox-Immune Modulating Phytomedicine: A Ferroptosis Induction, Exosomal Crosstalk, and Translational Oncology Perspective
2025
Mechanistic insights into the anticancer, anti-inflammatory, and antioxidant effects of yellowfin tuna collagen peptides using network pharmacology
2025
Pharmacoinformatics and ex vivo studies of carotenoids from green algae Caulerpa racemosa as functional biomolecules to modulate type-2 diabetes markers
2025
Targeting Redox Signaling Through Exosomal MicroRNA: Insights into Tumor Microenvironment and Precision Oncology
2025
Probing the Molecular Mechanisms of Kratom's Antipsychotic Effects through a Multi-modal Computational Approach
2025
Plant‐Derived Natural Products for Dietary Intervention in Overweight and Obese Individuals: A Systematic Review and Network Meta‐Analysis
2025
Integrated DNA Barcoding and Morphometric Characterization of Palm Weevils (Rhynchophorus spp.) in North Sulawesi
2025
Phytochemical composition and antioxidant activity of medicinal plants from three geothermal areas of Aceh Province, Indonesia
2025
Investigation on low-performance tuned-regressor of inhibitory concentration targeting the SARS-CoV-2 polyprotein 1ab
2025
In Silico Analysis of the Antigastritis Activity of Gedi (Abelmoschus manihot) Flower Flavonoids on H2 Receptor
2025
Therapeutic potential of propolis in alleviating inflammatory response and promoting wound healing in skin burn
2024
Rhynchophorus ferrugineus larvae: A novel source for combating broad-spectrum bacterial and fungal infections
2024
Revealing Novel Source of Breast Cancer Inhibitors from Seagrass Enhalus acoroides: In Silico and In Vitro Studies
2024
Unraveling Light-Activated Insulin Action in Regulating Blood Glucose: New Photoactivatable Insight as a Novel Modality in Diabetes Management
2024
Correction: Chakraborty et al. Bromelain a Potential Bioactive Compound: A Comprehensive Overview from a Pharmacological Perspective. Life 2021, 11, 317
2024
The Importance of Philanthropy Foundation for the Future Sustainability of Agriculture and Nutrition: An Opinion Study on Practical Applications, Policies, and Strategies
2024
Novel Functional Food Properties of Forest Onion (Eleutherine bulbosa Merr.) Phytochemicals for Treating Metabolic Syndrome: New Insights from a Combined Computational and In Vitro Approach
2024
Modulation of Apoptotic, Cell Cycle, DNA Repair, and Senescence Pathways by Marine Algae Peptides in Cancer Therapy
2024
Red ginger confers antioxidant activity, inhibits lipid and sugar metabolic enzymes, and downregulates miR-21/132 expression
2024
Molecular insights into the anti‐inflammatory activity of fermented pineapple juice using multimodal computational studies
2024
A comprehensive review on the antioxidant activities and health benefits of microgreens: current insights and future perspectives
2024
Critical review of self‐diagnosis of mental health conditions using artificial intelligence
2024
A network pharmacology approach to elucidate the anti-inflammatory and antioxidant effects of bitter leaf (Vernonia amygdalina Del.)
2024
Mechanistic Elucidation of green seaweed compounds in orthodontic relapse management via RANKL/TNF-α-mediated ROS/Keap1/Nrf2 signaling: In silico and Ex Vivo studies
2024
Immunoinformatics-Driven Strategies for Advancing Epitope-Based Vaccine Design for West Nile Virus
2024
Mechanism of Action of Isoflavone Derived from Soy-Based Tempeh as an Antioxidant and Breast Cancer Inhibitor via Potential Upregulation of miR-7-5p: A Multimodal Analysis Integrating Pharmacoinformatics and Cellular Studies
2024
Green Seaweed Caulerpa racemosa as a Novel Non-Small Cell Lung Cancer Inhibitor in Overcoming Tyrosine Kinase Inhibitor Resistance: An Analysis Employing Network Pharmacology, Molecular Docking, and In Vitro Research
2024
Functional food candidate from Indonesian green algae Caulerpa racemosa (Försskal) J. Agardh by two extraction methods: Metabolite profile, antioxidant activity, and cytotoxic properties
2024
Exploring the potential molecular targets of hydroxymethylbutyrate and glucosamine fortified whey protein drink to modulate sarcopenia and Alzheimer's disease by in silico and in vitro studies
2024
Identification of novel functional compounds from forest onion and its biological activities against breast cancer
2024
Antibacterial and Antioxidant Activity of Ecoenzyme Solution Prepared from Papaya, Pineapple, and Kasturi Orange Fruits: Experimental and Molecular Docking Studies
2023
2023
2023
2023
Monkeypox outbreak 2022: What we know so far and its potential drug targets and management strategies
2023
Algal-derived macromolecules and their composites: From synthetic biology to biomedical applications in bone and cardiovascular tissue engineering
2023
Dietary Supplementation of Caulerpa racemosa Ameliorates Cardiometabolic Syndrome via Regulation of PRMT-1/DDAH/ADMA Pathway and Gut Microbiome in Mice
2023
Mechanistic insights of Cucumis melo L. seeds for gastrointestinal muscle spasms through calcium signaling pathway–related gene regulation networks in WGCNA and in vitro, in vivo studies
2023
Configuration of gut bacterial community profile and their potential functionality in the digestive tract of the wild and cultivated Indonesian shortfin elver-phase eels (Anguilla bicolor bicolor McClelland, 1844)
2023
Clinical and oral microbiome pattern of halitosis patients with periodontitis and gingivitis
2023
Metagenomic Insight into the Microbiome and Virome Associated with Aedes aegypti Mosquitoes in Manado (North Sulawesi, Indonesia)
2023
Antimicrobial Potential of Rhynchophorus Beetle Larval Haemolymph Against Methicillin-Resistant Staphylococcus aureus and Neisseria gonorrhoeae
2023
Molecular Insight into the Pharmacological Potential of Clerodendrum minahassae Leaf Extract for Type-2 Diabetes Management Using the Network Pharmacology Approach
2023
A computational simulation appraisal of banana lectin as a potential anti-SARS-CoV-2 candidate by targeting the receptor-binding domain
2023
Fruit Bromelain-Derived Peptide Potentially Restrains the Attachment of SARS-CoV-2 Variants to hACE2: A Pharmacoinformatics Approach
2022
Phytochemical Compound Screening to Identify Novel Small Molecules against Dengue Virus: A Docking and Dynamics Study
2022
Hormonal Therapy for Gynecological Cancers: How Far Has Science Progressed toward Clinical Applications?
2022
Ginkgo biloba: A Treasure of Functional Phytochemicals with Multimedicinal Applications
2022
Marine Microbial-Derived Resource Exploration: Uncovering the Hidden Potential of Marine Carotenoids
2022
Crusted Scabies, a Neglected Tropical Disease: Case Series and Literature Review
2022
A Review of the Antimicrobial Potential of Musca domestica as a Natural Approach with Promising Prospects to Countermeasure Antibiotic Resistance
2022
A computational comparative analysis of the binding mechanism of molnupiravir's active metabolite to RNA‐dependent RNA polymerase of wild‐type and Delta subvariant AY.4 of SARS‐CoV‐2
2022
An Insight Based on Computational Analysis of the Interaction between the Receptor-Binding Domain of the Omicron Variants and Human Angiotensin-Converting Enzyme 2
2022
Computational prediction of the effect of mutations in the receptor-binding domain on the interaction between SARS-CoV-2 and human ACE2
2022
Can the SARS-CoV-2 Omicron Variant Confer Natural Immunity against COVID-19?
2022
4’-fluorouridine and its derivatives as potential COVID-19 oral drugs: a review
2022
Predictive Microbial Community and Functional Gene Expression Profiles in Pineapple Peel Fermentation Using 16S rRNA Gene Sequences
2022
2022
UNRAVELING ANTI-DIABETIC AND PHARMACOLOGICAL PROPERTIES OF GREEN GEDI, LEILEM, AND SESEWANUA USING A PHARMACOINFORMATICS APPROACH
2022
Green Synthesis and Antimicrobial Activities of Silver Nanoparticles Using Calotropis gigantea from Ie Seu-Um Geothermal Area, Aceh Province, Indonesia
2022
Study of Dengue Virus Transovarial Transmission in Aedes spp. in Ternate City Using Streptavidin-Biotin-Peroxidase Complex Immunohistochemistry
2022
2022
Designing an Epitope-Based Peptide Vaccine Derived from RNA-Dependent RNA Polymerase (RdRp) against Dengue Virus Serotype 2
2022
In Silico Identification of Promising New Pyrazole Derivative-Based Small Molecules for Modulating CRMP2, C-RAF, CYP17, VEGFR, C-KIT, and HDAC—Application towards Cancer Therapeutics
2022
Interactions of the Receptor Binding Domain of SARS-CoV-2 Variants with hACE2: Insights from Molecular Docking Analysis and Molecular Dynamic Simulation
2021
In Silico and In Vitro Evaluation of the Antimicrobial Potential of Bacillus cereus Isolated from Apis dorsata Gut against Neisseria gonorrhoeae
2021
A Comprehensive Review of the Potential Use of Green Tea Polyphenols in the Management of COVID-19
2021
Appraisal of Bioactive Compounds of Betel Fruit as Antimalarial Agents by Targeting Plasmepsin 1 and 2: A Computational Approach
2021
Optimum Processing Conditions for Bakasang Using the Response Surface Methodology with Central Composite Design (CCD)
2021
Bromelain a Potential Bioactive Compound: A Comprehensive Overview from a Pharmacological Perspective
2021
Molecular docking and dynamics study to explore phytochemical ligand molecules against the main protease of SARS-CoV-2 from extensive phytochemical datasets
2021
Impact of SARS-CoV-2 delta variant (B.1.617.2) in surging second wave of COVID-19 and efficacy of vaccines in tackling the ongoing pandemic
2021
In Silico Evaluation of Iranian Medicinal Plant Phytoconstituents as Inhibitors against Main Protease and the Receptor-Binding Domain of SARS-CoV-2
2021
Designing an epitope vaccine against Dermatophagoides pteronyssinus: An in silico study
2021
Synthesis of Chitosan-Silver Nanoparticle Composite Spheres and Their Antimicrobial Activities
2021
Phytochemical and antioxidant activities of Eucheuma spinosum as natural functional food from North Sulawesi waters, Indonesia.
Trina Ekawati Tallei
2021
Antimicrobial Activities of Rhopalaea-Associated Fungus Aspergillus flavus strain MFABU9
2020
Indigenous Lactic Acid Bacteria Isolated from Spontaneously Fermented Goat Milk as Potential Probiotics
2020
Potential of Plant Bioactive Compounds as SARS-CoV-2 Main Protease (Mpro) and Spike (S) Glycoprotein Inhibitors: A Molecular Docking Study
2020
Comparison of Bacterial Community Structure and Diversity in Traditional Gold Mining Waste Disposal Site and Rice Field by Using a Metabarcoding Approach
2020
2020
Data on the use of virgin coconut oil and bioethanol produced from sugar palm sap as raw materials for biodiesel synthesis
2020
Assessment of Genetic Variation in Apis nigrocincta (Hymenoptera: Apidae) in Sulawesi Revealed by Partial Mitochondrial Cytochrome Oxidase I Gene Sequences
2020
Betacyanin as Bioindicator Using Time-Temperature Integrator for Smart Packaging of Fresh Goat Milk
2020
Bacterial Composition, Community Structure, and Diversity in Apis nigrocincta Gut
2020
Biochemical and Computational Approach of Selected Phytocompounds from Tinospora crispa in the Management of COVID-19
2020
Antibacterial activities of culture-dependent bacteria isolated from apis nigrocincta gut.
Trina Ekawati Tallei
2020
Isolation and identification of arsenic-resistant bacteria for possible application in arsenic bioremediation.
Trina Ekawati Tallei
2020
Potential of organic mercury-resistant bacteria isolated from mercury contaminated sites for organic mercury remediation.
Trina Ekawati Tallei
2019
Antimicrobial activity screening of endophytic fungi extracts isolated from brown algae Padina sp.
Trina Ekawati Tallei
2019
Cytotoxic and antimicrobial activities of ethyl acetate extract of mangrove plant Scyphiphora hydrophyllacea C. F. Gaertn-associated fungi.
Trina Ekawati Tallei
2019
Growth response and production of purple sweet potatoes after provision of arbuscular mycorrhizal fungi and organic fertilizer.
Trina Ekawati Tallei
2019
Diversity and community composition of dragonfly (Insecta: Odonata) in Tangkoko, Nature Reserve, North Sulawesi, Indonesia.
Trina Ekawati Tallei
2017
Sequence analysis of the cytochrome C oxidase subunit I gene of Pseudagrion pilidorsum (Odonata: Coenagrionidae).
Trina Ekawati Tallei
2017
Butterfly diversity varies across habitat types in Tangkoko Nature Reserve North Sulawesi, Indonesia.
Trina Ekawati Tallei
2017
Sequence variation and phylogenetic analysis of Sansevieria trifasciata (Asparagaceae).
Trina Ekawati Tallei
2016
[Sequences and phylogenetic analysis of Syzygium (Myrtaceae) plants in North Sulawesi based on matK gene].
Trina Ekawati Tallei
2016
Association of Helicobacter pylori and left ventricular ejection fraction in patients with acute myocardial infarction.
Trina Ekawati Tallei
2016
Effects of arbuscular mycorrhiza inoculation on length, leaf number and flowering of Arachis pintoi.
Trina Ekawati Tallei
2016
DNA barcoding of Sangihe Nutmeg (Myristica fragrans) using matK gene.
Trina Ekawati Tallei
2015
Overproduction of mercuric reductase from mercury-resistant bacteria Klebsiella pneumoniae isolate A1.1.1.
Trina Ekawati Tallei
2015
Putative DNA-dependent RNA polymerase in mitochondrial plasmid of Paramecium caudatum stock GT704.
Trina Ekawati Tallei
2015
Density of Tangkasi (Tarsius spectrum) population and development of population estimation method based on duet call at Tangkoko-Batuangus Nature Reserve, North Sulawesi.
Trina Ekawati Tallei
2014
The yield, nitrogen content and dye's binding capacity of chitin and chitosan of rotifer Brachionus rotundiformis.
Trina Ekawati Tallei
2013
Local community-based initiatives of waste management activities on Bunaken Island in North Sulawesi, Indonesia.
Trina Ekawati Tallei
2013