Fatima Regina Mena Barreto Silva

LiveDNA ID: 55.6358

107 Publications

0 Editorial Roles

0 Projects

About

Professional Summary

Undergraduate in Chemistry License (Catholic University of Pelotas/Brazil), Master and PhD in Biochemistry (Federal University of Rio Grande do Sul/Brazil) and Pos-doc at Université de CAEN/France (UNICAEN). Supervisor of Master and PhD programs (member of the founding team) in the programs of Pharmacy: Pharmaceutical Drugs and Chemical Analyzes/Health Sciences (since 1999) and in the Biochemistry/Biological Sciences (since 2008). Full professor at Federal University of Santa Catarina (UFSC)/Brazil (since 2014). Coordinator of the following programs/projects: International Cooperation Program among UNICAEN and UFSC since 2007; International Project among University of Guelph/Canada and UFSC for Special Invited Professor supported by CNPq/Brazil (2014-2019); project for undergraduate, graduation (Master, PhD and Pos-Doc) exchanges students among UNICAEN and UFSC (2007-2021); project of international collaboration among Sorbonne Universités, Paris 6 (Pierre et Marie Curie) and UFSC (2011-2012); project of international collaboration among Biochemistry/UFSC; project of international collaboration among University of California, Riverside (UCR/USA) and UFSC (2000-2010); International collaboration among Universidad Nacional de Colombia, Bogota (since 2017) and UFSC; project of international collaboration among De Montfort University, Leicester, UK and UFSC (since 2017). Fellowship student of Japan International Cooperation Agency, Chiba/Japan (1998). Visiting Scientist at UCR/USA (2000 and 2002) and at UNICAEN (from 2007 – 2010). Invited Professor at UNICAEN/France in 2018 to the Biology undergraduate and graduation courses. Oral communication in international scientific meeting (Japan, Uruguay, USA, India, France, Poland, China, Greece and Canada). International Scientific Committee (Ciencia Y Tecnologia para el Desarrollo/CYTED). Lead Editor Guest for several journals (Life Sciences, CTMC, Pharmacologia, Frontiers in Endocrinology, Frontiers in Physiology, BioMed Res. Int., CDT, SciRes Lit. Nutrition & Food Sci). 119 international publications and 4 chapters of books (Nova Science Publishers, IN, Elsevier, Springer Berlin Heidelberg). H index 27 for 2079 citations; Web of Science February 2021. Supervision completed: 24 Masters, 12 PhD, 11 pos-doc and more than 60 undergraduate students with CNPq fellowship. As research experience, develop studies in Pharmacy related to Farmacognosie and Biochemistry focused on effect and mechanism of action of hormones, natural and synthetic compounds related to diabetes and male reproduction fertility. Lead the research group of Endocrinology at CNPq/Brazil since 1997.

Education

Academic Background

Ph.D. Federal University of Rio Grande do Sul, Brazil Biochemistry | Completed: 1995

Publications (107)

Selected Scholarly Contributions

Effects of Plant Extracts on Human Health—2nd Edition

Fátima Regina Mena Barreto Silva, Marcela Aragón Novoa

Nutrients | Journal Article

10.3390/nu18050732

2026

1α,25(OH)2 Vitamin D3 Signaling in Adipose Tissue: Bridging Classical and Non-Classical Pathways in Metabolic Regulation Complexity

Alice Lima Rosa Mendes, Paola Miranda Sulis, Murilo Ferenz, Bruna Antunes Zaniboni, Marcela Aragón, Guilherme Brasil Pintarelli, Daniela Ota Hisayasu Suzuki, Carine Royer, Fátima Regina Mena Barreto Silva

Nutrients | Journal Article

10.3390/nu18122026

2026

Clinical Electrophysiology and Mathematical Modeling for Precision Diagnosis of Infertility

Fernanda Carvalho Cavalari, Paola Sulis Mendes, Bruna Antunes Zaniboni, Carine Royer, Bárbara Ogliari Martins Taques, Karina Cesca, Marcela Aragón, Fátima Regina Mena Barreto Silva

Biomedicines | Journal Article

10.3390/biomedicines13020250

2025

Pyriproxyfen Disrupts the Ongoing Spermatogenesis Wave in Danio rerio Potentially Mediated by Voltage‐Dependent Calcium Channels and Protein Kinase C

Bruna Antunes Zaniboni, Vanessa Staldoni de Oliveira, Gabriel Adan Araujo Leite, Valdelúcia Maria Alves de Souza Grinevicius, Rozangela Curi Pedrosa, Fátima Regina Mena Barreto Silva

Journal of Applied Toxicology | Journal Article

10.1002/jat.4801

2025

Self-Emulsifying Drug Delivery System Enhances the Antidiabetic Activity of Passiflora ligularis Leaf Extract

Sandra M. Echeverry, Diana P. Rey, Ivonne H. Valderrama, Ingrid A. Rodriguez, Paula M. Sepúlveda, Bibiana Verlindo de Araujo, Fátima Regina Mena Barreto Silva, Diana Marcela Aragón

Pharmaceutics | Journal Article

10.3390/pharmaceutics17060730

2025

Unraveling the Antihyperglycemic Effects of Dipeptyl Peptidase-4 Inhibitors in Rodents: A Multi-Faceted Approach Combining Effects on Glucose Homeostasis, Molecular Docking, and ADMET Profiling

Raquel N. S. Roriz, Claudia J. P. Cardozo, Gabriela A. Freire, Caio B. R. Martins, Raimundo Rigoberto B. X. Filho, Landerson Lopes Pereira, Gisele F. P. Rangel, Tiago L. Sampaio, Lyanna R. Ribeiro, Gisele Silvestre Silva, Isabelle Maia, Deysi Viviana Tenazoa Wong, Daniele O. B. Sousa, Ariclécio Cunha de Oliveira, Eduardo Reina, Lidia Moreira Lima, Walter Peláez, Matheus Nunes da Rocha, Márcia Machado Marinho, Hélcio Silva dos Santos, Emmanuel Silva Marinho, Jane Eire Silva Alencar de Menezes, Fátima Regina Mena Barreto Silva, Kirley Marques Canuto, Nylane M. N. Alencar, Marisa Jadna Silva Frederico

Pharmaceuticals | Journal Article

10.3390/ph18101589

2025

Antidiabetic Effect of Passiflora ligularis Leaves in High Fat-Diet/Streptozotocin-Induced Diabetic Mice

Diana P. Rey, Sandra M. Echeverry, Ivonne H. Valderrama, Ingrid A. Rodriguez, Luis F. Ospina, Fatima Regina Mena Barreto Silva, Marcela Aragón

Nutrients | Journal Article

10.3390/nu16111669

2024

In vivo exposure to pyriproxyfen causes ovarian oxidative stress and inhibits follicle maturation in zebrafish

Vanessa Staldoni de Oliveira, Katiuska Marins, Ana Karla Bittecourt Mendes, Ariane Zamoner, Gabriel Adan Araujo Leite, Fátima Regina Mena Barreto Silva

Journal of Applied Toxicology | Journal Article

10.1002/jat.4425

2023

Dibutyl phthalate disrupts energy metabolism and morphology in the gills and induces hepatotoxicity in zebrafish

Keyla Rodrigues, Hemily Batista-Silva, Kieiv Resende Sousa de Moura, Glen Van Der Kraak, Fátima Regina Mena Barreto Silva

Fish Physiology and Biochemistry | Journal Article

10.1007/s10695-023-01227-z

2023

Electrophilic Agonists Modulate the Transient Receptor Potential Ankyrin-1 Channels Mediated by Insulin and Glucagon-like Peptide-1 Secretion for Glucose Homeostasis

Marisa Jadna Silva Frederico, Andreza Cipriani, Jocelyn Brice Alexandre Heim, Ana Karla Bittencourt Mendes, Marcela Aragón, Joana Margarida Gaspar, Nylane Maria Nunes De Alencar, Fátima Regina Mena Barreto Silva

Pharmaceuticals | Journal Article

10.3390/ph16081167

2023

Signal transduction of the insulin secretion induced by the chalcone analogue, (E)-3-(phenyl)-1-(3,4,5-trimethoxyphenyl)prop-2-en-1-one, and its role in glucose and lipid metabolism

Paola Miranda Sulis, Ana Karla Bittencourt Mendes, Thaís Alves Fernandes, Marisa Jadna Silva Frederico, Diana Patricia Rey, Marcela Aragón, Ketan C. Ruparelia, Fátima Regina Mena Barreto Silva

Biochimie | Journal Article

10.1016/j.biochi.2023.04.006

2023

Predictions from a mathematical approach to model ionic signaling for rapid responses of Sertoli cells exhibit similarities to pharmacological approaches

Bárbara O M Taques, Humberto R Gamba, Danusa Menegaz, Fátima R M B Silva, Daniela O H Suzuki

Biomedical Physics & Engineering Express | Journal Article

10.1088/2057-1976/acfb07

2023

Influence of the aquatic environment and 1α,25(OH)2 vitamin D3 on calcium influx in the intestine of adult zebrafish

Betina Fernanda Dambrós, Hemily Batista da Silva, Kieiv Resende Sousa de Moura, Allisson Jhonatan Gomes Castro, Glen Van Der Kraak, Fátima Regina Mena Barreto Silva

Biochimie | Journal Article

10.1016/j.biochi.2023.07.004

2023

Extract of Calyces from Physalis peruviana Reduces Insulin Resistance and Oxidative Stress in Streptozotocin-Induced Diabetic Mice

Ivonne Helena Valderrama, Sandra Milena Echeverry, Diana Patricia Rey, Ingrid Andrea Rodríguez, Fátima Regina Mena Barreto Silva, Geison M. Costa, Luis Fernando Ospina-Giraldo, Diana Marcela Aragón

Pharmaceutics | Journal Article

10.3390/pharmaceutics14122758

2022

In vivo and in vitro short-term bisphenol a exposures disrupt testicular energy metabolism and negatively impact spermatogenesis in zebrafish.

Batista-Silva, H., K. Rodrigues, K.R.S. de Moura, N. Elie, G.V.D. Kraak, C. Delalande and F.R.M.B. Silva,

Reprod. Toxicol., | Journal Article

10.1016/j.reprotox.2021.11.001

Fatima Regina Mena Barreto Silva

2022

Estradiol and 1α,25(OH)₂ vitamin D3 share plasma membrane downstream signal transduction through calcium influx and genomic activation in immature rat testis.

Zanatta, A.P., R. Gonçalves, F.O. da Silva, R.C. Pedrosa and L. Zanatta et al.,

Theriogenology, | Journal Article

10.1016/j.theriogenology.2021.05.030

Fatima Regina Mena Barreto Silva

2021

A Brazilian pulp and paper mill effluent disrupts energy metabolism in immature rat testis and alters Sertoli cell secretion and mitochondrial activity

Vanessa Staldoni de Oliveira, Allisson Jhonatan Gomes Castro, Juliana Tonietto Domingues, Ariane Zamoner Pacheco de Souza, Débora da Luz Scheffer, Alexandra Latini, Carlos Henrique Lemos Soares, Glen Van Der Kraak, Fátima Regina Mena Barreto Silva

Animal Reproduction | Journal Article

10.1590/1984-3143-ar2019-0116

2020

Guanosine neuroprotective action in hippocampal slices subjected to oxygen and glucose deprivation restores atp levels, lactate release and glutamate uptake impairment: involvement of nitric oxide.

Thomaz, D.T., R.R. Andreguetti, L.B. Binder, D.d. Scheffer, A.W. Corru00eaa, F.R.M.B. Silva and C.I. Tasca,

Neurochem. Res., | Journal Article

10.1007/s11064-020-03083-2

Fatima Regina Mena Barreto Silva

2020

Acute exposure to bis(2-ethylhexyl)phthalate disrupts calcium homeostasis, energy metabolism and induces oxidative stress in the testis of danio rerio.

Batista-Silva, H., B.F. Dambru00f3s, K. Rodrigues, P.A. Cesconetto and A. Zamoner et al.,

Biochimie, | Journal Article

10.1016/j.biochi.2020.05.002

Fatima Regina Mena Barreto Silva

2020

Targeting ROS overgeneration by N-benzyl-2-nitro-1-imidazole-acetamide as a potential therapeutic reposition approach for cancer therapy.

Zeferino R.C., N.S.R.S. Mota, V.M.A.S. Grinevicius, K.B. Filipe and P.M. Sulis et al.,

Invest. New Drugs, | Journal Article

10.1007/s10637-019-00820-5

Fatima Regina Mena Barreto Silva

2020

New ionic targets of 3,3u2032,5u2032-triiodothyronine at the plasma membrane of rat sertoli cells.

Zanatta, A.P., R. Gonu00e7alves, L. Zanatta, G.T. de Oliveria and A.L.L. Moraes et al.,

Biochim. Biophys. Acta (BBA) Biomembr., | Journal Article

10.1016/j.bbamem.2019.01.002

Fatima Regina Mena Barreto Silva

2019

Astragalin augments basal calcium influx and insulin secretion in rat pancreatic islets.

Rey D., P.M. Sulis, T.A. Fernandes, R. Gonçalves, M.J.S. Frederico, G.M. Costa, M. Aragon, L.F. Ospina and F.R.M.B. Silva,

Cell Calcium | Journal Article

10.1016/j.ceca.2019.03.009

Fatima Regina Mena Barreto Silva

2019

Insulin stimulus-secretion coupling is triggered by a novel thiazolidinedione/sulfonylurea hybrid in rat pancreatic islets.

Mendes, C.P., B.G. Postal, G.T.C. Oliveira, A.J.G. Castro and M.J.S. Frederico et al.,

J. Cell. Physiol., | Journal Article

10.1002/jcp.26746

Fatima Regina Mena Barreto Silva

2018

The potent insulin secretagogue effect of betulinic acid is mediated by potassium and chloride channels.

Castro, A.J.G., L.H. Cazarolli, L.C. Bretanha, P.M. Sulis and D.P.R. Padilla et al.,

Arch. Biochem. Biophy., | Journal Article

10.1016/j.abb.2018.04.015

Fatima Regina Mena Barreto Silva

2018

Fern-9(11)-ene-2a,3ß-diol action on insulin secretion under hyperglycemic conditions.

Castro, A.J.G., L.H. Cazarolli, G. Da Luz, D. Altenhofen and H.B. Da Silva et al.,

Biochemistry, | Journal Article

10.1021/acs.biochem.8b00302

Fatima Regina Mena Barreto Silva

2018

Experimentally-induced maternal hypothyroidism alters enzyme activities and the sensorimotor cortex of the offspring rats.

Domingues, J.T., C.S. Wajima, P.A. Cesconetto, E.B. Parisotto and E. Winkelmann-Duarte et al.,

Mol. Cell. Endocrinol., | Journal Article

10.1016/j.mce.2018.07.008

Fatima Regina Mena Barreto Silva

2018

Sulfonyl(thio)urea derivative induction of insulin secretion is mediated by potassium, calcium, and sodium channel signal transduction.

Sulis, P.M., B.F. Dambrós, A. Mascarello, A.R.S. Dos Santos and F.R.M.B. Silva et al.,

J. Cell. Physiol., | Journal Article

10.1002/jcp.27680

Fatima Regina Mena Barreto Silva

2018

A new polyacetylene glucoside from vernonia scorpioides and its potential antihyperglycemic effect.

Pollo L.A.E., M.J. Frederico, A.J. Bortoluzzi, F.R.M.B. Silva and M.W. Biavatti,

Chemico-Biological Interactions | Journal Article

10.1016/j.cbi.2017.11.003

Fatima Regina Mena Barreto Silva

2018

Brain bioenergetics in rats with acute hyperphenylalaninemia.

Dimer N.W., B.K. Ferreira, J.F. Agostini, M.L. Gomes, L.W. Kist, F. Malgarin, M. Carvalho-Silva, L.M. Gomes, J. Rebelo, M.J.S. Frederico, F.R.M.B. Silva, E.P. Rico, M.R. Bogo, E.L. Streck, G.C. Ferreira and P.F. Schuck,

Neurochemistry International | Journal Article

10.1016/j.neuint.2018.01.001

Fatima Regina Mena Barreto Silva

2018

Acute effect of bisphenol a: signaling pathways on calcium influx in immature rat testes.

Gonçalves R., A.P. Zanatta, F.C. Cavalari, M.A.W.d. Nascimento, C. Delalande-Lecapitaine, H. Bouraïma-Lelong and F.R.M.B. Silva,

Reproductive Toxicology | Journal Article

10.1016/j.reprotox.2018.02.009

Fatima Regina Mena Barreto Silva

2018

Exposure to a brazilian pulp mill effluent impacts the testis and liver in the zebrafish.

Castro A.J.G., I.E. Baptista, K.R.S.d. Moura, F. Padilha, J. Tonietto, A.Z.P.d. Souza, C.H.L. Soares, F.R.M.B. Silva and G.V.D. Kraak,

Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology | Journal Article

10.1016/j.cbpc.2018.02.005

Fatima Regina Mena Barreto Silva

2018

1,25(OH)₂ vitamin D3 signalling on immature rat Sertoli cells: gamma-glutamyl transpeptidase and glucose metabolism.

Gonçalves, R., A. Zamoner, L. Zanatta, A.P. Zanatta and F.R.M.B. Silva et al.,

J. Cell Commun. Signal., | Journal Article

10.1007/s12079-016-0367-1

Fatima Regina Mena Barreto Silva

2017

Oral mucosa model for electrochemotherapy treatment of dog mouth cancer: ex vivo, in silico, and in vivo experiments.

Suzuki, D.O.H., J.A. Berkenbrock, M.J.S. Frederico, F.R.M.B. Silva and M.M.M. Rangel,

Artificial Organs, | Journal Article

10.1111/aor.13003

Fatima Regina Mena Barreto Silva

2017

Mechanism of action of camphoryl-benzene sulfonamide derivative on glucose uptake in adipose tissue.

Frederico, M.J.S., A.J.G. Castro, V.A.M. Pinto, C.D.F. Ramos and F.R.M.B. Silva et al.,

J. Cell. Biochem., | Journal Article

10.1002/jcb.26506

Fatima Regina Mena Barreto Silva

2017

Reverse T3 interacts with αvβ3 integrin receptor and restores enzyme activities in the hippocampus of hypothyroid developing rats: Insight on signaling mechanisms

Domingues, J.T., D. Cattani, P.A. Cesconetto, B.A.N. De Almeida and P. Pierozan et al.,

Mol. Cellular Endocrinol., | Journal Article

10.1016/j.mce.2017.11.013

Fatima Regina Mena Barreto Silva

2017

Impairment of brain bioenergetics in animals submitted to hyperphenylalaninemia.

Schuck, P.F., N.W. Dimer, B.K. Ferreira, J.F. Agostini and M.L. Gomes et al.,

Free Radical Biol. Med., | Journal Article

10.1016/j.freeradbiomed.2017.10.273

Fatima Regina Mena Barreto Silva

2017

Triterpene derivative: A potential signaling pathway for the fern-9(11)-ene-2α,3β-diol on insulin secretion in pancreatic islet.

Da Luz, G., M.J.S. Frederico, A.J.G. Castro, A.L.L. Moraes and F.K. De Carvalho et al.,

Life Sci., | Journal Article

10.1016/j.lfs.2016.04.027

Fatima Regina Mena Barreto Silva

2016

Bis-pyrano prenyl isoflavone improves glucose homeostasis by inhibiting dipeptidyl peptidase-4 in hyperglycemic rats.

Altenhofen, D., G. Da Luz, M.J.S. Frederico, D. Venzke and M. Brich et al.,

J. Cell. Biochem., | Journal Article

10.1002/jcb.25614

Fatima Regina Mena Barreto Silva

2016

Acute effect of 3β-hidroxihop-22(29)ene on insulin secretion is mediated by GLP-1, potassium and calcium channels for the glucose homeostasis.

Castro, A.J.G., L.H. Cazarolli, F.K. De Carvalho, G. Da Luz and D. Altenhofen et al.,

J. Steroid Biochem. Mol. Biol., | Journal Article

10.1016/j.jsbmb.2015.03.011

Fatima Regina Mena Barreto Silva

2015

Neutrotoxic effects of fructose administration in rat brain: implications for fructosemia.

Macongonde, E.A., N.L.F. Costa, B.K. Ferreira, M.S. Biella and M.J.S. Frederico et al.,

An. Acad. Bras. Ciênc., | Journal Article

10.1590/0001-3765201520140720

Fatima Regina Mena Barreto Silva

2015

In vivo potential hypoglycemic and in vitro vasorelaxant effects of Cecropia glaziovii standardized extracts.

Arend, D.P., T.C. Dos Santos, L.H. Cazarolli, M.A. Hort and D. Sonaglio et al.,

Revista Brasileira De Farmacognosia, | Journal Article

10.1016/j.bjp.2015.05.010

Fatima Regina Mena Barreto Silva

2015

Incretinomimetic and insulinomimetic effect of (2E)-N′-(1′-Naphthyl)-3,4,5-Trimethoxybenzohydrazide for glycemic homeostasis.

Frederico, M.J.S., A. Mascarello, A.J.G. Castro, G. Da Luz and D. Altenhofen et al.,

J. Cell. Biochem. | Journal Article

10.1002/jcb.25403

Fatima Regina Mena Barreto Silva

2015

Factors related to overweight among university students.

Elias, R.G.M., W.F. De Faria, J.P. De Farias, F.P. Dos Santos, E.C. De Andrade Gonçalves and F.R.M.B. Silva,

Nutrire, | Journal Article

10.4322/2316-7874.52514

Fatima Regina Mena Barreto Silva

2015

Ameliorative potential of standardized fruit extract of Pterodon pubescens Benth on neuropathic pain in mice: Evidence for the mechanisms of action.

Nucci-Martins, C., D.F. Martins, L.F. Nascimento, D. Venzke and A.S. Oliveira et al.,

J. Ethnopharmacol., | Journal Article

10.1016/j.jep.2015.09.005

Fatima Regina Mena Barreto Silva

2015

N-methyl-d-aspartate preconditioning prevents quinolinic acid-induced deregulation of glutamate and calcium homeostasis in mice hippocampus.

Vandresen-Filho, S., P.C. Severino, L.C. Constantino, W.C. Martins and S. Molz et al.,

Neurotox. Res., | Journal Article

10.1007/s12640-014-9496-6

Fatima Regina Mena Barreto Silva

2014

Novel sulfonyl(thio)urea derivatives act efficiently both as insulin secretagogues and as insulinomimetic compounds.

Mascarello, A., M.J.S. Frederico, A.J.G. Castro, C.P. Mendes and M.F. Dutra et al.,

Eur. J. Med. Chem., | Journal Article

10.1016/j.ejmech.2014.09.007

Fatima Regina Mena Barreto Silva

2014

Natural and synthetic chalcones.

Cazarolli, L.H., V.D. Kappel, A.P. Zanatta, D.O.H. Suzuki and R.A. Yunes et al.,

Stud. Nat. Prod. Chem., | Journal Article

10.1016/b978-0-444-62615-8.00002-3

Fatima Regina Mena Barreto Silva

2013

Betulinic acid and 1,25(OH)2 vitamin D3 share intracellular signal transduction in glucose homeostasis in soleus muscle.

Castro, A.J.G., M.J.S. Frederico, L.H. Cazarolli, L.C. Bretanha, L.De.C. Tavares, Z.Da.S. Buss, M.F. Dutra, A.Z.P.D. Souza, M.G. Pizzolatti and F.R.M.B. Silva,

Int. J. Biochem. Cell Biol., | Journal Article

10.1016/j.biocel.2013.11.020

Fatima Regina Mena Barreto Silva

2013

Hot topic: Synthetic, natural and related compounds: New approach to chronic diseases studies.

Silva, F.R.M.B. and L.H. Cazarolli,

Curr. Topics Med. Chem., | Journal Article

Fatima Regina Mena Barreto Silva

2013

Integrin participates in the effect of thyroxine on plasma membrane in immature rat testis.

Zanatta, A.P., L. Zanatta, R. Goncalves, A. Zamoner and F.R.M.B. Silva,

Biochim. Biophys. Acta General Subjects, | Journal Article

10.1016/j.bbagen.2012.10.022

Fatima Regina Mena Barreto Silva

2013

Acute effect of β-sitosterol on calcium uptake mediates anti-inflammatory effect in murine activated neutrophils.

Liz, R., L. Zanatta, G.O. dos Reis, H. Horst, M.G. Pizzolatti , F.R.M.B. Silva and T.S. Frode,

J. Pharm. Pharmacol., | Journal Article

10.1111/j.2042-7158.2012.01568.x

Fatima Regina Mena Barreto Silva

2013

The role of calcium in intracellular pathways of rutin in rat pancreatic islets: Potential insulin secretagogue effect.

Kappel, V.D., M.J.S. Frederico, B.G. Postal, C.P. Mendes, L.H. Cazarolli and F.R.M.B. Silva,

Eur. J. Pharmacol., | Journal Article

10.1016/j.ejphar.2013.01.055

Fatima Regina Mena Barreto Silva

2013

Roundup disrupts male reproductive functions by triggering calcium-mediated cell death in rat testis and Sertoli cells.

Cavalli, V.L.L.O., D. Cattani, C.E.H. Rieg, L. Zanatta and P. Pierozan et al.,

Free Radical Biol. Med., | Journal Article

10.1016/j.freeradbiomed.2013.06.043

Fatima Regina Mena Barreto Silva

2013

Rutin potentiates calcium uptake via voltage-dependent calcium channel associated with stimulation of glucose uptake in skeletal muscle.

Kappel, V.D., L. Zanatta, B.G. Postal and F.R.M.B. Silva,

Arch. Biochem. Biophys., | Journal Article

10.1016/j.abb.2013.01.008

Fatima Regina Mena Barreto Silva

2013

Congenital hypothyroidism alters the oxidative status, enzyme activities and morphological parameters in the hippocampus of developing rats.

Cattani, D., P.B. Goulart, V.L. de Liz Oliveira Cavalli, E. Winkelmann-Duarte and A.Q. dos Santos et al.,

Mol. Cell. Endocrinol., | Journal Article

10.1016/j.mce.2013.05.001

Fatima Regina Mena Barreto Silva

2013

Involvement of GLUT-4 in the stimulatory effect of rutin on glucose uptake in rat soleus muscle.

Kappel, V.D., L.H. Cazarolli, D.F. Pereira, B.G. Postal, A. Zamoner, F.H. Reginatto and F.R.M.B. Silva,

J. Pharm. Pharmacol., | Journal Article

10.1111/jphp.12066

Fatima Regina Mena Barreto Silva

2013

Insulin signaling: A potential signaling pathway for the stimulatory effect of kaempferitrin on glucose uptake in skeletal muscle.

Cazarolli, L.H., D.F. Pereira, V.D. Kappel, P. Folador, S. Figueiredo Mdos, M.G. Pizzolatti and F.R. Silva,

Eur. J. Pharmacol., | Journal Article

10.1016/j.ejphar.2013.02.029

Fatima Regina Mena Barreto Silva

2013

1α,25-Dihydroxyvitamin D3 mechanism of action: Modulation of L-type calcium channels leading to calcium uptake and intermediate filament phosphorylation in cerebral cortex of young rats.

Zanatta, L., P.B. Goulart, R. Goncalves, P. Pierozan and E.C. Winkelmann-Duarte et al.,

Biochim. Biophys. Acta Mol. Cell Res., | Journal Article

10.1016/j.bbamcr.2012.06.023

Fatima Regina Mena Barreto Silva

2012

1α,25(OH)2-vitamin D3 stimulates rapid plasma membrane calcium influx via MAPK activation in immature rat Sertoli cells.

Rosso, A., M. Pansera, A. Zamoner, L. Zanatta, H. Bouraima-Lelong, S. Carreau and F.R.M.B. Silva,

Biochimie, | Journal Article

10.1016/j.biochi.2011.10.001

Fatima Regina Mena Barreto Silva

2012

Short and long-term effects of Baccharis articulate on glucose homeostasis.

Kappel, V.D., D.F. Pereira, L.H. Cazarolli, S.M. Guesser and C.H.B. da Silva et al.,

Molecules, | Journal Article

10.3390/molecules17066754

Fatima Regina Mena Barreto Silva

2012

Influence of the traditional Brazilian drink Ilex paraguariensis tea on glucose homeostasis.

Pereira, D.F., V.D. Kappel, L.H. Cazarolli, A.A. Boligon and M.L. Athayde et al.,

Phytomedicine, | Journal Article

10.1016/j.phymed.2012.05.008

Fatima Regina Mena Barreto Silva

2012

Acylhydrazones contribute to serum glucose homeostasis through dual physiological targets.

Frederico, M.J.S., A.J.G. Castro, A. Mascarello, C.P. Mendes and V.D. Kappel et al.,

Curr. Topics Med. Chem., | Journal Article

10.2174/1568026611212190003

Fatima Regina Mena Barreto Silva

2012

Acute antihyperglycemic role of crude extract, fractions and flavonoids from Averrhoa carambola.

Cazarolli, L.H., V.D. Kappel, D.F. Pereira, H.H. Moresco, I.M.C. Brighente, M.G. Pizzolatti and F.R.M.B. Silva,

Fitoterapia, | Journal Article

Fatima Regina Mena Barreto Silva

2012

Regulation of aromatase expression by 1,25(OH)2 vitamin D3 in rat testicular cells.

Zanatta, L., H. Bouraima, D.L. Christelle, F.R.M.B. Silva and S. Carreau,

Reprod. Fertility Dev., | Journal Article

10.1071/RD10163

Fatima Regina Mena Barreto Silva

2011

Aromatase, estrogens and testicular germ cell development.

Carreau, S., H. Bouraima-Lelong, C. Boism, L. Zanatta, F.R.M.B. Silva and C. Delalande,

Immunol. Endocrine Metab. Agents Med. Chem., | Journal Article

10.2174/187152211794519430

Fatima Regina Mena Barreto Silva

2011

Effect of 1α,25-dihydroxyvitamin D3 in plasma membrane targets in immature rat testis: Ionic channels and gamma-glutamyl transpeptidase activity.

Zanatta, L., A. Zamoner, R. Goncalves, A.P. Zanatta and H. Bouraima-Lelong et al.,

Arch. Biochem. Biophy., | Journal Article

10.1016/j.abb.2011.09.001

Fatima Regina Mena Barreto Silva

2011

International symposium on cell signaling.

Silva, F R.M.B., A.Z.P. de Souza and S. Carreau,

Life Sci., | Journal Article

Fatima Regina Mena Barreto Silva

2011

Estrogen signaling in testicular cells.

Carreau, S., C. Bois, L. Zanatta, F.R.M.B. Silva, H. Bouraima-Lelong and C. Delalande,

Life Sci., | Journal Article

10.1016/j.lfs.2011.06.004

Fatima Regina Mena Barreto Silva

2011

Membrane-initiated actions of thyroid hormones on the male reproductive system.

Zamoner, A., R. Pessoa-Pureur and F.R.M.B. Silva,

Life Sci., | Journal Article

10.1016/j.lfs.2011.04.006

Fatima Regina Mena Barreto Silva

2011

1α,25-dihydroxyvitamin D₃ signaling pathways on calcium uptake in 30-day-old rat sertoli cells.

Zanatta, L., A. Zamoner, R. Goncalves, A.P. Zanatta, H. Bouraima-Lelong, S. Carreau and F.R.M.B. Silva,

Biochemistry, | Journal Article

10.1021/bi201113n

Fatima Regina Mena Barreto Silva

2011

Nongenomic and genomic effects of 1α,25(OH)2 vitamin D3 in rat testis.

Zanatta, L., A. Zamoner, A.P. Zanatta, H. Bouraima-Lelong and C. Delalande et al.,

Life Sci., | Journal Article

10.1016/j.lfs.2011.04.008

Fatima Regina Mena Barreto Silva

2011

Effects of flavonoids on α-glucosidase activity: Potential targets for glucose homeostasis.

Pereira, D.F., L.H. Cazarolli, C. Lavado, V. Mengatto and M.S. Figueiredo et al.,

Nutrition, | Journal Article

10.1016/j.nut.2011.01.008

Fatima Regina Mena Barreto Silva

2011

Antihyperglycemic activity of naphthylchalcones.

Damazio, R.G., A.P. Zanatta, L.H. Cazarolli, L.D. Chiaradia and A. Mascarello et al.,

Eur. J. Med. Chem., | Journal Article

10.1016/j.ejmech.2009.12.017

Fatima Regina Mena Barreto Silva

2010

Rapid stimulatory effect of thyroxine on plasma membrane transport systems: Calcium uptake and neutral amino acid accumulation in immature rat testis.

Menegaz, D., C. Royer, A. Rosso, A.Z.P. de Souza, A.R.S. dos Santos and F.R.M.B. Silva,

Int. J. Biochem. Cell Biol., | Journal Article

10.1016/j.biocel.2010.03.015

Fatima Regina Mena Barreto Silva

2010

1α,25(OH)2-Vitamin D3 stimulation of secretion via chloride channel activation in Sertoli cells.

Menegaz, D., A. Barrientos-Duran, A. Kline, F.R.M.B. Silva, A.W. Norman, M.T. Mizwicki and L.P. Zanello,

J. Steroid Biochem. Mol. Biol., | Journal Article

10.1016/j.jsbmb.2010.01.011

Fatima Regina Mena Barreto Silva

2010

Potential insulin secretagogue effects of isovitexin and swertisin isolated from Wilbrandia ebracteata roots in non-diabetic rats.

Folador, P., L.H. Cazarolli, A.C. Gazola, F.He. Reginatto, E.P. Schenkel and F.R.M.B. Silva,

Fitoterapia, | Journal Article

10.1016/j.fitote.2010.07.022

Fatima Regina Mena Barreto Silva

2010

Theoretical and experimental analysis of electroporated.

Suzuki, D.O.H., A. Ramos, M.C.M. Ribeiro, L.H. Cazarolli, F.R. Silva, L.D. Leite and J.L.B. Marques,

IEEE Trans. Biomed. Eng., | Journal Article

Fatima Regina Mena Barreto Silva

2010

Role of 1α,25(OH)₂ vitamin D₃ on α-[1-14C]MeAIB accumulation in immature rat testis.

Menegaz, D., A. Rosso, C. Royer, L.D. Leite, A.R.S. Santos and F.R.M.B. Silva,

Steroids, | Journal Article

10.1016/j.steroids.2008.11.015

Fatima Regina Mena Barreto Silva

2009

Mechanism of action of the stimulatory effect of apigenin-6-C-(2"-O-alpha-L-rhamnopyranosyl)-B-L-fucopyranoside on 14C-glucose uptake.

Cazarolli, L.H., P. Folador, H.H. Moresco, I.M.C. Brighente, M.G. Pizzolatti and F.R.M.B. Silva,

Chem. Biol. Interact., | Journal Article

Fatima Regina Mena Barreto Silva

2009

Stimulatory effect of apigenin-6-β-L-fucopyranoside on insulin secretion and glycogen synthesis.

Cazarolli, L.H., P. Folador, H.H. Moresco, I.M.C. Brighente, M.G. Pizzolatti and F.R.M.B. Silva,

Eur. J. Med. Chem., | Journal Article

Fatima Regina Mena Barreto Silva

2009

Nitrochalcones: Potential in vivo insulin secretagogues.

Damazio, R.G., A.P. Zanatta, L.H. Cazarolli, A. Mascarello and L.D. Chiaradia et al.,

Biochimie, | Journal Article

10.1016/j.biochi.2009.09.002

Fatima Regina Mena Barreto Silva

2009

Propylthiouracil-induced congenital hypothyroidism upregulates vimentin phosphorylation and depletes antioxidant defences in immature rat testis.

Zamoner, A., K.P. Barreto, D.W. Filho, F. Sell and V.M. Woehl et al.,

J. Mol. Endocrinol., | Journal Article

Fatima Regina Mena Barreto Silva

2008

Influence of chalcone analogues on serum glucose levels in hyperglycemic rats.

Alberton, E.H., R.G. Damazio, L.H. Cazarolli, L.D. Chiaradia and P.C. Leal et al.,

Chem. Biol. Interact., | Journal Article

10.1016/j.cbi.2007.11.001

Fatima Regina Mena Barreto Silva

2008

Insulinomimetic effect of kaempferol 3-neohesperidoside on the rat soleus muscle.

Zanatta, L., A. Rosso, P. Folador, M.S.R.B. Figueiredo, M.G. Pizzolatti, L.D. Leite and F.R.M.B. Silva,

J. Nat. Prod., | Journal Article

10.1021/np070358+

Fatima Regina Mena Barreto Silva

2008

Nongenomic actions of thyroxine modulate intermediate filament phosphorylation in cerebral cortex of rats.

Zamoner, A., L. Heimfarth, S.O. Loureiro, C. Royer, F.R.M.B. Silva and R.P. Pureur,

Neuroscience, | Journal Article

10.1016/j.neuroscience.2008.07.059

Fatima Regina Mena Barreto Silva

2008

Flavonoids: Cellular and molecular mechanism of action in glucose homeostasis.

Cazarolli, L.H., L. Zanatta, E.H. Alberton, M.S.R.B. Figueiredo and P. Folador et al.,

Mini-Rev. Med. Chem., | Journal Article

10.2174/138955708785740580

Fatima Regina Mena Barreto Silva

2008

Flavonoids: Prospective drug candidates.

Cazarolli, L.H., L. Zanatta, E.H. Alberton, M.S.R.B. Figueiredo and P. Folador et al.,

Mini-Rev. Med. Chem., | Journal Article

10.2174/138955708786369564

Fatima Regina Mena Barreto Silva

2008

Monosaccharides and the VO(IV) metal ion: Equilibrium, thermal studies and hypoglycemic effect.

Guiotoku, M., F.R.M.B. Silva, J.C. Azzolini, A.L.R. Merce, A.S. Mangrich, L.F. Sala and B. Szpoganicz,

Polyhedron, | Journal Article

10.1016/j.poly.2006.10.032

Fatima Regina Mena Barreto Silva

2007

Ionic involvement and kinase activity on the mechanism of nongenomic action of thyroid hormones on ⁴⁵Ca²⁺ uptake in cerebral cortex from young rats.

Zamoner, A., C. Royer, K.P. Barreto, R. Pessoa-Pureur and F.R.M.B. Silva,

Neurosci. Res., | Journal Article

10.1016/j.neures.2006.09.012

Fatima Regina Mena Barreto Silva

2007

Hyperthyroidism in the developing rat testis is associated with oxidative stress and hyperphosphorylated vimentin accumulation.

Zamoner, A., K.P. Barreto, D.W. Filho, F. Sell and V.M. Woehl et al.,

Mol. Cell. Endocrinol., | Journal Article

10.1016/j.mce.2007.01.005

Fatima Regina Mena Barreto Silva

2007

Influence of oral glutamine and glucose on markers of oxidative stress in a paraquat rat model.

Sand, C.V., T.O. Vieira, T.B. Oliveira, D.W. Filho, F.R.M.B. Silva and T.B. Pasa,

Eur. e-J. Clin. Nutr. Metab., | Journal Article

10.1016/j.eclnm.2007.03.004

Fatima Regina Mena Barreto Silva

2007

Thyroid hormones reorganize the cytoskeleton of glial cells through GFAP phosphorylation and RHOA-dependent mechanisms.

Zamoner, A., C. Funchal, M.C. Jacques-Silva, C. Gottfried, F.R.M.B. Silva and R.P. Pureur,

Cell. Mol. Neurobiol., | Journal Article

10.1007/s10571-006-9084-2

Fatima Regina Mena Barreto Silva

2007

Restoration of transmembrane potential using morphological operators and adaptive alpha-trimmed mean filtering.

Palodeto, V., D.O.H. Suzuki, E.V. Garcia, C. Royer, L.D. Leite, F.R.M.B. Silva and J.L.B. Marques,

IFMBE Proc., | Journal Article

10.1007/978-3-540-36841-0_299

Fatima Regina Mena Barreto Silva

2007

Effect of crude extract and fractions from Vitex megapotamica leaves on hyperglycemia in alloxan-diabetic rats.

Zanatta, L., E. de Sousa, L.H. Cazarolli, A. Cunha Jr., A.M.G. Pizzolatti, B. Szpoganicz and F.R.M.B. Silva,

J. Ethnopharmacol., | Journal Article

Fatima Regina Mena Barreto Silva

2007

Follow-up studies on glycosylated flavonoids and their complexes with vanadium: their anti-hyperglycemic potential role in diabetes.

Cazarolli, L.H., L. Zanatta, A.P. Jorge, E. de Sousa and H. Horst et al.,

Chem. Biol. Interact., | Journal Article

10.1016/j.cbi.2006.07.010

Fatima Regina Mena Barreto Silva

2006

Genomic-independent action of thyroid hormones on NTPDase activities in Sertoli cell cultures from congenital hypothyroid rats.

Zamoner, A., A.N. Bruno, E.A. Casali, P.F. Corbelini and G.P. Diniz et al.,

Life Sci., | Journal Article

10.1016/j.lfs.2006.08.020

Fatima Regina Mena Barreto Silva

2006

Short-term effects of thyroid hormones on cytoskeletal proteins are mediated by gabaergic mechanisms in slices of cerebral cortex from young rats.

Zamoner, A., C. Funchal, L. Heimfarth, F.R.M.B. Silva and R.P. Pureur,

Cell. Mol. Neurobiol., | Journal Article

10.1007/s10571-006-9027-y

Fatima Regina Mena Barreto Silva

2006

Rapid responses to thyroxine in the testis: Active protein synthesis-independent pathway.

Menegaz, D., A. Zamoner, C. Royer, L.D. Leite, Z.A. Bortolotto and F.R.M.B. Silva,

Mol. Cell. Endocrinol., | Journal Article

10.1016/j.mce.2005.11.019

Fatima Regina Mena Barreto Silva

2006

Involvement of calcium-dependent mechanisms in T₃-induced phosphorylation of vimentin of immature rat testis.

Zamoner, A., P.F. Corbelini, C. Funchal, D. Menegaz, F.R.M.B. Silva and R. Pessoa-Pureur,

Life Sci., | Journal Article

10.1016/j.lfs.2005.05.042

Fatima Regina Mena Barreto Silva

2005

Hypoglycemic effect and antioxidant potential of kaempferol-3,7-O-(α)-dirhamnoside from Bauhinia forcata leaves.

De Sousa, E., L. Zanatta, I. Seifriz, T.B. Creczynski-Pasa, M.G. Pizzolatti, B. Szpoganicz and F.R.M.B. Silva,

J. Nat. Prod., | Journal Article

10.1021/np030513u

Fatima Regina Mena Barreto Silva

2004

Insulinomimetic effects of kaempferitrin on glycaemia and on 14C-glucose uptake in rat soleus muscle.

Jorge, A.P., H. Horst, E. de Sousa, M.G. Pizzolatti and F.R.M.B. Silva,

Chem. Biol. Interact., | Journal Article

10.1016/j.cbi.2004.07.001

Fatima Regina Mena Barreto Silva

2004

Involvement of K⁺channels and calcium-dependent pathways in the action of T₃ on amino acid accumulation and membrane potential in Sertoli cells of immature rat testis.

Volpato, K.C., D. Menegaz, L.D. Leite, K.P. Barreto, E.V. Garcia and F.R.M.B. Silva,

Life Sci., | Journal Article

10.1016/j.lfs.2003.08.005

Fatima Regina Mena Barreto Silva

2004

Rapid signal transduction in sertoli cells.

Silva, F.R.M.B., L.D. Leite and G.F. Wassermann,

Eur. J. Endocrinol., | Journal Article

10.1530/eje.0.1470425

Fatima Regina Mena Barreto Silva

2002

A specific binding protein/receptor for 1α,25-dihydroxyvitamin D₃ is present in an intestinal caveolae membrane fraction.

Norman, A.W., C.J. Olivera, F.R.M.B. Silva and J.E. Bishop,

Biochem. Biophys. Res. Commun., | Journal Article

10.1016/S0006-291X(02)02482-8

Fatima Regina Mena Barreto Silva

2002

Acute effect of Bauhinia forficata on serum glucose levels in normal and alloxan-induced diabetic rats.

Silva, F.R.M.B., B. Szpoganicz, M.G. Pizzolatti, M.A. Willrich and E. de Sousa,

J. Ethnopharmacol., | Journal Article

10.1016/S0378-8741(02)00193-9

Fatima Regina Mena Barreto Silva

2002

Structure function studies: Identification of vitamin D analogs for the ligand-binding domains of important proteins in the vitamin D-endocrine system.

Norman, A.W. and F.R.M.B. Silva,

Rev. Endocrine Metab. Disorders, | Journal Article

10.1023/A:1010067030049

Fatima Regina Mena Barreto Silva

2001

Effect of 3,5,3′-triiodo-L-thyronine on amino acid accumulation and membrane potential in Sertoli cells of the rat testis.

Silva, F.R.M.B., L.D. Leite, K.P. Barreto, C. D'Agostini and A. Zamoner,

Life Sci., | Journal Article

10.1016/S0024-3205(01)01186-9

Fatima Regina Mena Barreto Silva

2001