About
Professional SummaryDr. Carlos Eduardo Fonseca-Alves is currently working as Visiting Researcher at Department of Biomedical Sciences at University of Guelph, ON, and also working as Researcher. He obtained his PhD in Veterinary Medicine from University of Sao Paulo State - UNESP. He has published 14 international peer review articles, 33 abstract in international meetings as author/co-author. He is also a reviewer of many journals.
Education
Academic Background-
Ph.D. Universidade Estadual Paulista Julio de Mesquita Filho, Brazil Veterinary Medicine | Completed: 2006
Publications (117)
Selected Scholarly Contributions
Immunohistochemical investigation of the stem cell landscape of canine prostate cancer
2026
Evaluation of cyclin-dependent kinase 4 immunolabelling and a germline p.G201S variant as predictors of clinical outcome in canine mammary tumours: a preliminary study
2026
2026
Immunomodulation of the Prostate Tumor Microenvironment Following Inorganic Arsenic Exposure
2026
Ozonated Water Modulates Cell Proliferation and Vascular Density in Solid Ehrlich Tumor of Mice
2026
SET protein expression in canine neoplasms: evaluation of predictive potential
2026
Primary T-Cell Lymphoma of the Prostate in a Dog – Case Report
2025
Influence of Ozonated Water on Solid Ehrlich Tumor Induced in MICE: Clinical and Anatomopathological Study
2025
Canine prostate cancer cell transcriptome reveals important dysregulation in PI3K/AKT/mTOR pathway
2025
Antitumor Effect of Curcumin, D6 Turmeric, and Hydrochloride Mitoxantrone on Canine and Human Urothelial Cancer Cells
2025
Effects of ozone therapy applied topically, by bagging, or both on the healing of clean wounds induced in rat’s skin
2024
Intratesticular transplantation of allogenic mesenchymal stem cells mitigates testicular destruction after induced heat stress in Miniature-horse stallions
2024
Long-term survival of a cat with a metastatic gastrointestinal stromal tumor
2024
Cytotoxic effects of crotoxin from Crotalus durissus terrificus snake in canine mammary tumor cell lines
2024
Lapatinib antitumor effect is associated with PI3K and MAPK pathway: An analysis in human and canine prostate cancer cells
2024
2024
Immunohistochemistry Screening of Different Tyrosine Kinase Receptors in Canine Solid Tumors—Part I: Proposal of a Receptor Panel to Predict Therapies
2024
Transcriptomic analysis of mouse TRAMP cell lines and tumors provide insights into shared pathways and therapeutic targets
2024
In Vitro Antitumor Effect of Oils Rich in CBD and THC Cannabis Extract in Canine Prostate Carcinoma Cell Lines
2024
The Effects of Dietary Orange Peel Fragments Enriched with Zinc and Vitamins C and E on the Antioxidant and Immune Responses of Nile Tilapia under Stress Conditions
2024
Histochemical Characterisation of the Turquoise‐Fronted Parrot (Amazona aestiva) Digestive Tract
2024
Canine Adipose-Derived Mesenchymal Stromal Cells Reduce Cell Viability and Migration of Metastatic Canine Oral Melanoma Cell Lines In Vitro
2024
Characterization of nonpathological intrascleral cartilage in the domestic sheep (Ovis aries)
2023
Diagnosis, Prognosis, and Treatment of Canine Hemangiosarcoma: A Review Based on a Consensus Organized by the Brazilian Association of Veterinary Oncology, ABROVET
2023
Fatores clínicos e patológicos associados ao prognóstico de gatas acometidas por neoplasias mamárias
2023
Proposing Clinicopathological Staging and Mitotic Count as Prognostic Factors for Canine Soft Tissue Sarcomas
2023
Detection of Equus caballus Papillomavirus in Equine Aural Plaque Samples
2023
Is Osteopontin a Good Marker for Bone Metastasis in Canine Mammary Gland Tumor and Prostate Cancer?
2023
Epidemiological characterization of notified human brucellosis cases in Southern Brazil
2022
P-Glycoprotein and Androgen Receptor Expression Reveals Independence of Canine Prostate Cancer from Androgen Hormone Stimulation
2022
2022
Diagnosis, Prognosis and Treatment of Canine Cutaneous and Subcutaneous Mast Cell Tumors
2022
Pituitary Carcinoma in a Bitch: Clinical, Tomographic, Histopathological and Immunohistochemistry Findings
2022
Stephanofilariasis in Holstein Cows - Diagnostic Approach In Southern Brazil
2022
Comparative Pathobiology of Canine and Human Prostate Cancer: State of the Art and Future Directions
2022
Grading Systems for Canine Urothelial Carcinoma of the Bladder: A Comparative Overview
2022
Mutational Signature and Integrative Genomic Analysis of Human Papillomavirus-Associated Penile Squamous Cell Carcinomas from Latin American Patients
2022
Immunohematological features of free-living Alouatta belzebul (Linnaeus, 1766) red-handed howler monkeys in the Eastern Amazon
2022
Firocoxib as a Potential Neoadjuvant Treatment in Canine Patients with Triple-Negative Mammary Gland Tumors
2022
Experimental transmission of Leishmania (Leishmania) amazonensis to immunosuppressed mice through the bite of Lutzomyia longipalpis (Diptera: Psychodidae) results in cutaneous leishmaniasis
2021
Elucidating tumor immunosurveillance and immunoediting: a comprehensive review
2021
Effect of low-level laser therapy on the membrane induced by the Masquelet technique at an orthotopic site in rabbits
2021
Proteomics Approach of Rapamycin Anti-Tumoral Effect on Primary and Metastatic Canine Mammary Tumor Cells In Vitro
2021
Preparation and characterization of leukocyte‐ and platelet‐rich fibrin membrane derived from cats' blood
2021
Structural and Ultrastructural Morphological Evaluation of Giant Anteater (Myrmecophaga tridactyla) Prostate Gland
2021
A Comparative in Silico Analysis of CD24’s Prognostic Value in Human and Canine Prostate Cancer
2021
Morphological and Molecular Characterization of Proliferative Inflammatory Atrophy in Canine Prostatic Samples
2021
Effects of Lapatinib on HER2-Positive and HER2-Negative Canine Mammary Carcinoma Cells Cultured In Vitro
2021
Expression and prognostic significance of vascular endothelial growth factor‐A (VEGF‐A) and its receptor in canine prostate cancer
2021
Comparative analysis of the hormone production and gene expression profiles in ovine uterus tissue during oestrus cycle synchronized using medroxyprogesterone acetate plus eCG and prostaglandin analogue
2021
Investigation of Prognostic Value of Claudin-5, PSMA, and Ki67 Expression in Canine Splenic Hemangiosarcoma
2021
Master Regulators of Epithelial-Mesenchymal Transition and WNT Signaling Pathways in Juvenile Nasopharyngeal Angiofibromas
2021
VEGF Expression, Cellular Infiltration, and Intratumoral Collagen Levels after Electroporation-Based Treatment of Dogs with Cutaneous Squamous Cell Carcinoma
2021
Epidemiological characterization of reported cases of brucellosis in cattle in the western region of the state of Santa Catarina, Brazil
2020
Serological prevalence of bovine viral diarrhoea (BVD-1) in non-vaccinated dairy cattle in the municipality of Realeza-Paraná
2020
Controlled Drug Delivery Vehicles in Veterinary Oncology: State-of-the-Art and Future Directions
2020
Germline Mutation in MUS81 Resulting in Impaired Protein Stability is Associated with Familial Breast and Thyroid Cancer
2020
Outcome Following Curative-Intent Electrochemotherapy for Extramedullary Plasmocytoma in Dogs – Case Reports
2020
Inflammatory Breast Cancer: Clinical Implications of Genomic Alterations and Mutational Profiling
2020
Mechanisms of Resistance to Chemotherapy in Breast Cancer and Possible Targets in Drug Delivery Systems
2020
Deregulation of VEGFR-2 and PDGFR Expression and Microvascular Density in a Triple-Negative Model of Canine Malignant Mammary Tumors with Lymph Node or Lung Metastasis
2019
Characterization of Collagen Fibers (I, III, IV) and Elastin of Normal and Neoplastic Canine Prostatic Tissues
2019
Comprehensive Genomic Profiling of Androgen-Receptor-Negative Canine Prostate Cancer
2019
Long-Term Survival of a Cat with Primary Leiomyosarcoma of the Urinary Bladder
2019
Clinical, pathological and therapeutic findings on lingual rhabdomyosarcoma in a dog - case report
2019
p-mTOR, p-4EBP-1 and eIF4E expression in canine prostatic carcinoma.
Carlos Eduardo Fonseca Alves
2019
An immunohistochemical study of T and B lymphocyte density in prostatic hyperplasia and prostate carcinoma in dogs.
Carlos Eduardo Fonseca Alves
2019
Tumor-infiltrating CD4+ and CD8+ lymphocytes and macrophages are associated with prognostic factors in triple-negative canine mammary complex type carcinoma.
Carlos Eduardo Fonseca Alves
2019
Histopathological terminology standards for the reporting of prostatic epithelial lesions in dogs.
Carlos Eduardo Fonseca Alves
2019
Tumour-infiltrating T cells are increased in canine prostate cancer tissue: Potential prognostic implications?
Carlos Eduardo Fonseca Alves
2019
Pathology of the canine prostate: Recommendations of an oncology/pathology working group.
Carlos Eduardo Fonseca Alves
2019
Immunophenotype of proliferative inflammatory atrophy (PIA) in the canine prostate.
Carlos Eduardo Fonseca Alves
2019
Characterization of OCT3/4, Nestin, NANOG, CD44 and CD24 as stem cell markers in canine prostate cancer.
Carlos Eduardo Fonseca Alves
2019
Isolation, cultivation and immunofluorescence characterization of lamellar keratinocytes from equine hoof by using explants.
Carlos Eduardo Fonseca Alves
2019
Association between decreased expression of estrogen receptor alpha, androgen receptor and phosphatase and tensin homolog immunoexpression in the canine prostate.
Carlos Eduardo Fonseca Alves
2019
Immunohistochemical panel to characterize canine prostate carcinomas according to aberrant p63 expression
2018
2018
Clinicopathological and immunohistochemical description of an intrapelvic hepatoid gland carcinoma in a 14-year-old Teckel dog.
Carlos Eduardo Fonseca Alves
2018
Long-term survival in two dogs with intracranial meningioma treated with lomustine and prednisone.
Carlos Eduardo Fonseca Alves
2018
Hydroxyurea-induced onychomadesis in a dog with chronic myeloid leukemia: A case report.
Carlos Eduardo Fonseca Alves
2018
Vitrification of cat ovarian tissue: Does fragment size matters?
Carlos Eduardo Fonseca Alves
2018
Evaluation of NKX3. 1 and C-MYC expression in canine prostatic cancer.
Carlos Eduardo Fonseca Alves
2018
Brazilian consensus for the diagnosis, treatment and prognosis of cutaneous mast cell tumors in dogs.
Carlos Eduardo Fonseca Alves
2018
Allogeneic mesenchymal stem cell transplantation in healthy equine superficial digital flexor tendon: A study of the local inflammatory response.
Carlos Eduardo Fonseca Alves
2018
Deregulation of E-cadherin, β-catenin, APC and Caveolin-1 expression occurs in canine prostate cancer and metastatic processes.
Carlos Eduardo Fonseca Alves
2018
Primary diffuse mammary hemangiosarcoma in a female dog.
Carlos Eduardo Fonseca Alves
2018
[Undifferentiated carcinoma of the exocrine pancreas in dog: Case report].
Carlos Eduardo Fonseca Alves
2017
Pilot assessment of vascular endothelial growth factor receptors and trafficking pathways in recurrent and metastatic canine subcutaneous mast cell tumours.
Carlos Eduardo Fonseca Alves
2017
[Carcinogenic process of canine prostate: WNT canonical pathway and its comparative study].
Carlos Eduardo Fonseca Alves
2017
[Inflammatory mammary carcinoma-A comparative approach].
Carlos Eduardo Fonseca Alves
2016
[Photosensitization in a kid goat-Case report].
Carlos Eduardo Fonseca Alves
2016
[Enterocutaneous fistula in a mare-Case roport].
Carlos Eduardo Fonseca Alves
2016
Alterations in PTEN, MDM2, TP53 and AR protein and gene expression are associated with canine prostate carcinogenesis.
Carlos Eduardo Fonseca Alves
2016
Overexpression of ephrin A3 receptor in canine prostatic carcinoma.
Carlos Eduardo Fonseca Alves
2016
Metastatic kidney carcinoma causing paralysis of pelvic limbs in a dog.
Carlos Eduardo Fonseca Alves
2016
Metronomic chemotherapy in small animal practice: An update.
Carlos Eduardo Fonseca Alves
2016
Evidence of epithelial–mesenchymal transition in canine prostate cancer metastasis
2015
In vivo analysis of oxidative stress relationship in embryofetal pancreas development of the offspring of diabetic rats.
Carlos Eduardo Fonseca Alves
2015
Cyclooxygenase Inhibitor Associated with Carboplatin in Treatment of Metastatic Nasal Carcinoma in Dog
2014
Neoadjuvant chemotherapy with vinblastine and lomustine in the treatment of a canine cutaneous mast cell tumous with multiple negative prognostic factors and survival over two years.
Carlos Eduardo Fonseca Alves
2014
Hyaluronic acid behavior in the lamina propria of the larynx with advancing age.
Carlos Eduardo Fonseca Alves
2014
Female paraurethral prostate gland in bitches.
Carlos Eduardo Fonseca Alves
2013
Alterations of C-MYC, NKX3.1 and E-cadherin expression in canine prostate carcinogenesis.
Carlos Eduardo Fonseca Alves
2013
Zinc-responsive dermatosis in a mixed breed dog.
Carlos Eduardo Fonseca Alves
2013
Canine prostate cancer: Would the dog be an important model for the study of new drugs?
Carlos Eduardo Fonseca Alves
2013
Role of selective cyclo-oxygenase-2 inhibitor celecoxib in canine osteosarcoma cell culture.
Carlos Eduardo Fonseca Alves
2013
Nodular dermatofibrosis in a German shepherd dog: case report.
Carlos Eduardo Fonseca Alves
2013
Impact of introduced nile tilapia (Oreochromis niloticus) on non-native aquatic ecosystems.
Carlos Eduardo Fonseca Alves
2013
Juvenile cellulitis in a puppy-case reports.
Carlos Eduardo Fonseca Alves
2012
Prostatic abscess in dogs: Report of 15 cases.
Carlos Eduardo Fonseca Alves
2012
Eosinophilic gastroenteritis in basset hound dog.
Carlos Eduardo Fonseca Alves
2012
Tear production and conjunctival goblet cell density in shih-tzu dogs.
Carlos Eduardo Fonseca Alves
2011
Therapeutic protocol for canine liver cirrhosis-use in three animals.
Carlos Eduardo Fonseca Alves
2011
Reintroduction in nature of giant anteater (Myrmecophaga tridactyla) after osteosynthesis of radius and ulna.
Carlos Eduardo Fonseca Alves
2011
Linhares, Studies on canine visceral leishmaniasis in the municipality of Goiania, Goias, Brazil.
Carlos Eduardo Fonseca Alves
2011
Prostatic histological evaluation in adult not castrated dogs.
Carlos Eduardo Fonseca Alves
2010
Canine lymphocytic thyroiditis in a Bull Terrier.
Carlos Eduardo Fonseca Alves
2008