Education
Academic Background-
Ph.D. University of Yaounde I, Yaounde, Cameroon Pharmacology and Clinical Microbiology | Completed: 2005
Publications (105)
Selected Scholarly Contributions
Phytochemical profiling and identification of potentially bioactive compounds from Balanites aegyptiaca (L.) Delile trunk bark extract that induce DNA damage in human breast cancer cells
2026
Triterpenoid saponins from the fruit pulp of
Tetrapleura tetraptera
(Fabaceae)
2026
Phytochemical Composition and Antipseudomonal Activity of
Allanblackia gabonensis
(Clusiaceae) Extracts Alone and With Antibiotics Against Drug‐Resistant Clinical Isolates
2026
In Silico Prediction of Aridanin as a Potential Anticancer and Antibacterial Agent
2026
Evaluation of anti-staphylococcal activity and acute toxicity of hexane extracts of Macaranga occidentalis (Mull. Arg.) Mull. Arg (Euphobiaceae)
2026
Talinum fruticosum (L.) Juss. (Talinaceae), an Edible and Medicinal Plant, Enhances the Activity of Antibiotics Against Multidrug-Resistant Gram-Negative Bacteria
2026
Anti-Pseudomonal Activity, Antibiotic Resistance Modulation Potential, and Effect of Dichloromethane/Methanol Extract of
Imperata cylindrica
(Gramineae) on the Antioxidant System of Multidrug-Resistant
Pseudomonas aeruginosa
2026
Natural Products in
Gambeya lacourtiana
(Sapotaceae): Identification, In Vitro Cytoxicity, and Deep Learning‐Based Pharmacokinetic Prediction
2026
Fecal Carriage of Multidrug‐Resistant
Staphylococcus aureus
in Hypertensive Patients at the Douala Laquintinie Hospital: Prevalence and Resistance Patterns
2025
In Vitro Antibacterial Potential of Herbal Beverage Extracts From Cinnamon, Clove, and Thyme and Their Interactive Antimicrobial Profile With Selected Antibiotics Against Drug‐Resistant Clinical Pathogens
2025
Phytochemical Composition, Antibacterial Activity, Modes of Action, and Antibiotic Resistance–Modifying Effects of
Harungana madagascariensis
(Hypericaceae) Against Multidrug‐Resistant
Pseudomonas aeruginosa
2025
Antibiotic Resistance Profile of Enterovirulent
E. coli
Isolates Harboring Broad‐Spectrum Beta‐Lactamase Genes in Cancer Patients at the Laquintinie Hospital in Douala, Littoral Region, Cameroon
2025
Resistance Profiles and Virulence Factors of Enteric
Escherichia coli
in Chronic Kidney Disease Patients at Laquintinie Hospital in Douala, Cameroon
2025
Detection of blaTEM, blaOXA, blaCTX-M, and blaSHV genes of antibiotic resistance in diarrheagenic E. coli causing enteric infection in hypertensive patients at Laquintinie Hospital, Littoral Region of Cameroon
2025
Prevalence and Resistance Profile of Enteric Bacteria Isolated in Chronic Kidney Disease Patients at Laquintinie Hospital of Douala: A Cross-Sectional Study
2025
Prevalence of ESBL resistance genes and fecal carriage of multidrug-resistant Pseudomonas aeruginosa isolates from patients with chronic kidney disease at the Laquintinie Hospital in Douala, Littoral Region, Cameroon
2025
Potential of methanol extracts of Nephelium lappaceum (Sapindaceae) and Hyphaene thebaica (Arecaceae) as adjuvants to enhance the efficacy of antibiotics against critical class priority bacteria
2025
HPLC-ESI-QTOF-MS profiling of antibacterial bioactive solvent fractions of Senna alata (L.) roxb (Fabaceae) leaves, and in silico prediction of pharmacokinetic, drug-likeness, and toxicity of major phyto-components
2025
Cytotoxicity, acute and subchronic toxicity of the methanol extract from the fruits of Psorospermun febrifugum Spach (Hypericaceae) in Wistar albino rats
2025
Antibacterial flavonoids from Tetrapleura tetraptera (Fabaceae) fruit pulp, in silico studies
2025
Antibacterial Potential of a New Endiandric Acid From Beilschmiedia acuta (Lauraceae) Against Drug‐resistant Bacteria
2025
Multidrug Resistance of Bacteria Causing Enteric Infections in Patients with Arterial Hypertension at the Douala Laquintinie Hospital in Cameroon
2025
Antibacterial activity and antibiotic-potentiating effects of Termnalia laxiflora and Azadirachta indica against multidrug-resistant Staphylococcus aureus
2025
Toxicological assessment of Balanites aegyptiaca (L.) Delile trunk bark extract in Wistar rats and its phytochemical components
2025
Enhancing tetracycline, ceftazidime, and amoxicillin efficacy with hydroethanolic extracts of Mammea africana (Calophyllaceae) and Baillonella toxisperma (Sapotaceae) against clinically relevant drug-resistant enteric bacteria
2025
A three-year review (2023–2025) on the effectiveness of natural products from plants in treating major types of fibrosis
2025
Antibacterial activity of phytochemicals from Bauhinia thonningii significantly increased in the presence of the efflux pump inhibitor, phenylalanine-arginine-β-naphthylamide towards multidrug-resistant phenotypes
2024
Antibacterial potential and modes of action of the methanol extracts of Elephantopus mollis Kunth (Asteraceae) against multidrug-resistant Gram-negative bacteria overexpressing efflux pumps
2024
Antibacterial potential and modes of action of methanol extracts of flowers and leaves of Vernonia glabra (Steetz) Vatke (Asteraceae) against multidrug-resistant Gram-negative bacteria overexpressing efflux pumps
2024
Botanicals from Aframomum letestuanum Gagnep. (Zingiberaceae) can overcome the multidrug resistance of Klebsiella species overexpressing AcrAB-TolC efflux pumps
2024
Botanical from the bark of Zizyphus jujuba Mill. (Rhamnaceae) had weak anti-Klebsiella activity, but strongly potentiated the effects of antibiotics against multidrug-resistant phenotypes
2024
A moderately active crude methanol extract from the whole plant of Kalanchoe crenata (Andrews) Haw. (Crassulaceae) strongly potentiated the effect of antibiotics against multidrug-resistant Gram-negative bacteria
2024
Hypericum roeperianum bark extract suppresses breast cancer proliferation via induction of apoptosis, downregulation of PI3K/Akt/mTOR signaling cascade and reversal of EMT
2024
Frequency of Fecal Carriage of ESBL Resistance Genes in Multidrug‐Resistant Pseudomonas aeruginosa Isolates from Cancer Patients at Laquintinie Hospital, Douala, Littoral Region, Cameroon
2024
Phytochemical Composition, Antibacterial, and Antibiotic‐Resistance Modulatory Activity of Extracts of Lippia multiflora Moldenke, Terminalia mollis M. A. Lawson, and Cinchona officinalis L. Against Multidrug‐Resistant Pseudomonas aeruginosa
2024
Multidrug Resistant Enteric Bacteria from Cancer Patients Admitted in Douala Laquintinie Hospital, Littoral Region of Cameroon
2024
Haematological Profile and Antibiotic Resistance of Bacteria Responsible for Enteric Infections Isolated From Patients Suffering From Malaria and Enteric Infections on Consultation at the Dschang Regional Hospital
2024
Antibacterial activity of Sarcocephalus latifolius and Acacia sieberiana, and the effect of their association with antibiotics against multidrug-resistant Staphylococcus aureus
2024
Antibacterial activity and antibiotic-potentiating effects of methanol extracts from Ocimum basilicum and Sarcocephalus latifolius against multidrug-resistant Gram-negative bacteria overexpressing efflux pumps
2024
The best African plant-derived antibacterial products for clinical perspectives: The state-of-the-art
2024
Antibiotic Resistance Profile of Staphylococcus aureus in Cancer Patients at Laquintinie Hospital in Douala, Littoral Region, Cameroon
2024
Antibacterial and antibiotic-potentiation activities of methanol extracts from Blighia sapida K. D. Koenig (Sapindaceae) against Gram-negative multidrug-resistant bacteria overexpressing efflux pumps
2024
Botanicals from the flowers of Vernonia calvoana and the leaves of Senna spectabilis showed anti-Klebsiella activity and potentiated the activity of antibiotics against multidrug-resistant phenotypes overexpressing efflux pumps
2024
Acute and subchronic toxicological profile of Ziziphus jujuba Mill. bark methanolic extract toward Swiss albino rats
2024
Guttiferone BL from the Fruits of Allanblackia gabonensis Induces Mitochondrial‐Dependent Apoptosis in PA‐1 Ovarian Cancer Cells
2023
Phytochemistry and pharmacology of Imperata cylindrica: A comprehensive review
2023
Anti-staphylococcal and antibiotic-potentiating activities of botanicals from nine Cameroonian food plants towards multidrug-resistant phenotypes
2023
Botanicals from nine selected Cameroonian edible plants displayed Anti-pseudomonas effects and potentiated the activities of antibiotics against multidrug-resistant phenotypes over-expressing MexAB-OprM efflux pumps
2023
Anti-Klebsiella and antibiotic-potentiation activities of the methanol extracts of seven Cameroonian dietary plants against multidrug-resistant phenotypes over-expressing AcrAB-TolC efflux pumps
2023
Antibacterial potential and modes of action of botanicals from Momordica foetida (Cucurbitaceae) against multidrug-resistant bacteria expressing active efflux pumps
2023
Psidium guajava (Myrtaceae) re-sensitizes multidrug-resistant Pseudomonas aeruginosa over-expressing MexAB-OprM efflux pumps to commonly prescribed antibiotics
2023
In Silico and In Vitro Identification of P-Glycoprotein Inhibitors from a Library of 375 Phytochemicals
2023
Exploring Mangifera indica (Anacardiaceae) leaf and bark methanol extracts as potential adjuvant therapy in the management of multidrug-resistant Staphylococcus aureus
2023
Unveiling the antibacterial potential and antibiotic-resistance breaker activity of Syzygium jambos (Myrtaceae) towards critical-class priority pathogen Klebsiella isolates
2023
Methanol extract from the seeds of Persea americana displays antibacterial and wound healing activities in rat model
2022
Antibacterial and antibiotic-potentiating activities of Desmodium uncinatum, Neoboutonia glabrescens, Ternstroemia cameroonensis and eight other Cameroonian medicinal plants against multi-drug resistant bacteria expressing active efflux pumps
2022
Antibacterial and antibiotic-potentiating activities of nine Cameroonian medicinal plants against multidrug-resistant bacteria expressing active efflux pumps
2022
Antibacterial and antibiotic-modulating activities of Rhinella jimi and three other animal extracts against multidrug-resistant Gram-negative phenotypes
2022
Modes of action of the methanol extract and 3-O-[β-galactopyranosyl-(1→4)-β-D-galactopyranosyl]-oleanolic acid from Acacia polyacantha against multi-resistant Gram-negative bacteria
2022
Botanical from the Fruits Mesocarp of Raphia vinifera Displays Antiproliferative Activity and Is Harmless as Evidenced by Toxicological Assessments
2022
2022
Antibacterial and antibiotic-potentiation activity of the constituents from aerial part of Donella welwitshii (Sapotaceae) against multidrug resistant phenotypes
2022
Antibacterial and antibiotic-potentiation activity of Coffea arabica and six other Cameroonian edible plants against multidrug-resistant phenotypes
2022
Cellular modes of action of the methanol extract from the aerial parts of Psychotria sycophylla (K.Schum.) Petit (Rubiaceae) against multidrug-resistant bacteria
2022
Antibacterial and antibiotic-potentiation activities of the hydro-ethanolic extract and protoberberine alkaloids from the stem bark of Enantia chlorantha against multidrug-resistant bacteria expressing active efflux pumps
2022
Acute and sub-chronic toxicities assessment of methanol bark extract of Hypericum roeperianum in rats
2022
In vitro antibacterial and antibiotic-potentiation activities of five edible plant extracts and mode of action against several MDR Gram-negative phenotypes
2021
Antibiotic-potentiation activities of three animal species extracts, Bitis arietans, Helix aspersa, and Aristaeomorpha foliacea and mode of action against MDR Gram-negative bacteria phenotypes
2021
Antibacterial and Therapeutic Potentials of the Capsicum annuum Extract against Infected Wound in a Rat Model with Its Mechanisms of Antibacterial Action
2021
In Vitro Anticancer Activity of Imperata cylindrica Root’s Extract toward Human Cervical Cancer and Identification of Potential Bioactive Compounds
2021
Botanical from Piper capense Fruit Can Help to Combat the Melanoma as Demonstrated by In Vitro and In Vivo Studies
2021
Cytotoxic phytochemicals from the crude extract of Tetrapleura tetraptera fruits towards multi-factorial drug resistant cancer cells
2021
Cytotoxicity of botanicals and isolated phytochemicals from Araliopsis soyauxii Engl. (Rutaceae) towards a panel of human cancer cells
2021
Bioactivity of fractions and constituents of Piper capense fruits towards a broad panel of cancer cells
2021
An Efflux Pumps Inhibitor Significantly Improved the Antibacterial Activity of Botanicals from Plectranthus glandulosus towards MDR Phenotypes
2021
CD24 gene inhibition and TIMP-4 gene upregulation by Imperata cylindrica's root extract prevents metastasis of CaSki cells via inhibiting PI3K/Akt/snail signaling pathway and blocking EMT
2021
Prenylated Flavonoids and C-15 Isoprenoid Analogues with Antibacterial Properties from the Whole Plant of Imperata cylindrica (L.) Raeusch (Gramineae)
2021
Phytochemical analysis and antibiotic-modulating activity of Cocos nucifera, Glycine max and Musa sapientum methanol extracts against multidrug resistant Gram-negative bacteria
2021
Botanicals and phytochemicals from the bark of Hypericum roeperianum (Hypericaceae) had strong antibacterial activity and showed synergistic effects with antibiotics against multidrug-resistant bacteria expressing active efflux pumps
2021
Cytotoxic Constituents of the Bark of Hypericum roeperianum towards Multidrug‐Resistant Cancer Cells
2020
Acute and Subacute Toxicity Profiles of the Methanol Extract of Lycopersicon esculentum L. Leaves (Tomato), a Botanical with Promising In Vitro Anticancer Potential
2020
Antistaphylococcal Activity of Extracts, Fractions, and Compounds of Acacia polyacantha Wild (Fabaceae)
2020
Synthesis and Biological Evaluation of Four New Ricinoleic Acid-Derived 1-O-alkylglycerols
2020
Methanol Extracts from Manilkara zapota with Moderate Antibacterial Activity Displayed Strong Antibiotic-Modulating Effects against Multidrug-Resistant Phenotypes
2020
Antibacterial potential and mechanism of action of botanicals and phytochemicals from Stachytarpheta cayennensis (Verbenaceae) against Gram-negative multidrug-resistant phenotypes expressing efflux pumps
2020
8,8-bis-(Dihydroconiferyl)-diferulate displayed impressive cytotoxicity towards a panel of human and animal cancer cells
2020
Haematological Features and Urologic Pathologies of Diabetic Subjects at Bafoussam Regional Hospital: A Cross-Sectional Study
2020
N-acetylglycoside of oleanolic acid (aridanin) displays promising cytotoxicity towards human and animal cancer cells, inducing apoptotic, ferroptotic and necroptotic cell death
2020
A botanical from the antiproliferative Cameroonian spice, Imperata cylindrica is safe at lower doses, as demonstrated by oral acute and sub-chronic toxicity screenings
2020
Botanical from the medicinal spice, Piper capense is safe as demonstrated by oral acute and subchronic toxicity investigations
2020
Botanicals from the leaves of Acacia sieberiana had better cytotoxic effects than isolated phytochemicals towards MDR cancer cells lines
2020
Bark extract of Cassia sieberiana DC. (Caesalpiniaceae) displayed good antibacterial activity against MDR gram-negative phenotypes in the presence of phenylalanine-arginine β-naphthylamide
2020
Antioxidant Activities of Methanol Extracts of Thirteen Cameroonian Antibacterial Dietary Plants
2020
Cinnamomum zeylanicum, Dichrostachys glomerata and three other plants had anti-staphylococcal and antibiotic-modifying activity against drug-resistant phenotypes
2019
Antibacterial and Antibiotic Modifying Potential of Crude Extracts, Fractions, and Compounds from Acacia polyacantha Willd. against MDR Gram-Negative Bacteria
2019
Prevalence of Metabolic Syndrome and Its Components in Bamboutos Division’s Adults, West Region of Cameroon
2019
Cytotoxicity of isoflavones and biflavonoids from Ormocarpum kirkii towards multi-factorial drug resistant cancer
2019
Collateral sensitivity of drug-resistant ABCB5- and mutation-activated EGFR overexpressing cells towards resveratrol due to modulation of SIRT1 expression
2019
Cytotoxicity of ungeremine towards multi-factorial drug resistant cancer cells and induction of apoptosis, ferroptosis, necroptosis and autophagy
2019
Cinnamomum zeylanicum, Dichrostachys glomerata and three other plants had anti-staphylococcal and antibiotic-modifying activity against drug-resistant phenotypes
2019
Cytotoxicity of Crude Extract and Isolated Constituents of theDichrostachys cinereaBark towards Multifactorial Drug-Resistant Cancer Cells
2019
Antibiotic Resistance of Enteric Bacteria in HIV-Infected Patients at the Banka Ad-Lucem Hospital, West Region of Cameroon
2019
Evaluation of Acute and Subacute Toxicities of Psidium guajava Methanolic Bark Extract: A Botanical with In Vitro Antiproliferative Potential
2019
Anti-staphylococcal activity and antibiotic-modulating effect of Olax subscorpioidea, Piper guineense, Scorodophloeus zenkeri, Fagara leprieurii, and Monodora myristica against resistant phenotypes
2018
2018