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Daniel Udofia Owu

Daniel Udofia Owu

LiveDNA ID: 234.26510
74 Publications
0 Editorial Roles
0 Projects

Education

Academic Background
  • Ph.D. University of Calabar, Calabar, Nigeria Cardiovascular Physiology | Completed: 2009
  • M.Sc. University of Calabar, Calabar, Nigeria Physiology | Completed: 1997
  • B.Sc. University of Calabar, Calabar, Nigeria Physiology | Completed: 1990

Publications (74)

Selected Scholarly Contributions
Phytochemicals of Rwandan Plants and Their Mechanisms for Cardiovascular Health: A Systematic Review
Gaudence Ndinganire, Akaninyene Ubong Ime, Birhanie Muluken Walle, Diresbachew Wondimu Haile, Onyinye Cynthia Okeke, Abul-Rahuf Aderemi Feyitimi, Abdulazeez Jimoh, Ejike Daniel Eze, Elemi John Ani, Daniel Udofia Owu
Natural Product Communications | Journal Article
Crossref
2026
Cardiovascular adaptation to spinal anesthesia-induced hypotension during scheduled cesarean section: the paradigm of ionized calcium and nitric oxide in a prospective cohort study
Mpeyou Sani Mohamed, Daniel Ewa Ikpi, Ngokoh Ghislain Nyemji, Nga Nomo Serge Vivier, Ndam Gbetnkom Pascal, Favour Nyoh Beshel, Daniel Udofia Owu
BMC Anesthesiology | Journal Article
Crossref
2026
Mechanisms of Neuroimmune Interactions in Stress Physiology, Health Implications, and Emerging Therapeutic Targets.
Regan Mujinya, Swase Dominic Terkimbi, Elna Owembabazi, Swabra Yahya Umutoni, Joseph Kibirige, Partick Maduabuchi Aja, Victor Otu Oka, Daniel Udofia Owu
F1000Research | Journal Article
Crossref
2026
Administration of Aspirin and Aqueous Leaf Extract of Terminalia Catappa Reduces Leukocytosis with Risk of Developing Thrombocytosis in Diabetic Wistar Rats
Ezekiel Etim Ben, Justin Atiang Beshel, Asuquo Etim Asuquo, Idara Asuquo Okon, Daniel Udofia Owu
Cardiovascular & Hematological Agents in Medicinal Chemistry | Journal Article
Crossref
2026
Gas Chromatography-Mass spectrometric (GC-MS) Revealed Bioactive Constituents of Brassica Oleracea var. Viridis (Collard Greens) Used as Ethnomedicine to Treat Male Infertility in Uganda
Emmanuel Orire Ikuomola, Daniel Udofia Owu, Victor Otu Oka, Sunday Agba Bisong, Ugwu Okechukwu Paul-Chima, Patrick Maduabuchi Aja
F1000Research | Journal Article
Crossref
2025
In silico molecular docking study and antihypertensive property of Gongronema latifolium Benth. ethanol leaf extract in dexamethasone-induced hypertension in Wistar rats
Idara Asuquo Okon, Justin Atiang Beshel, Erdi Can Aytar, Daniel Udofia Owu
Phytomedicine Plus | Journal Article
Crossref
2025
Is the use of anthracyclines implicated in myocardial injury? Investigating the cardio modulatory effects of naringenin and apocynin in doxorubicin-induced cardiotoxicity in rats
Justin Atiang Beshel, Samuel Usoh Ukweni, Idara Asuquo Okon, Daniel Udofia Owu
Toxicology Reports | Journal Article
Crossref
2025
Nephroprotective activity of naringenin in gentamicin-induced nephrotoxicity in male Wistar rats: In-vivo and in-silico evaluation
William Bwambale, Victor Otu Oka, Ekom Monday Etukudo, Daniel Udofia Owu, Etah Etah Nkanu, Idara Asuquo Okon, Saali Dembe Emmanuel, Umar Uthman Shehu, Ntoni Wilber, Allan Kambere, Richard Arinaitwe, Venesio Bwambale
Pharmacological Research - Natural Products | Journal Article
Crossref
2025
Unveiling the Fertility Potential of Brassica oleracea: In Silico and In vivo Insights into Protein Kinase B (PKB/AKT1) and Epidermal Growth Factor Receptor (EGFR) Inhibition
Emmanuel Orire Ikuomola, Daniel Udofia Owu, Victor Otu Oka, Umar Uthman Shehu, Ismahil Adekunle Adeniyi, Ilemobayo Victor Fasogbon, Ibe Micheal Usman, Ekom Monday Etukudo, Patrick Maduabuchi Aja
F1000Research | Journal Article
Crossref
2025
THE PROTECTIVE ROLE OF FLAVONOIDS IN AMNESIA -SYSTEMATIC REVIEW
Regan Mujinya, Swase Dominic Terkimbi, Victor Otu Oka, Monday Etukudo Ekon, Makena Wusa, Elna Owembabazi, Patrick Aja Maduabuchi, Daniel Udofia Owu
F1000Research | Journal Article
Crossref
2025
Gas Chromatography-Mass spectrometry (GC-MS) Revealed Bioactive Constituents of Brassica oleracea var. viridis (Collard Greens) Used to Treat Male Infertility in Uganda.
Emmanuel Orire Ikuomola, Daniel Udofia Owu, Victor Otu Oka, Sunday Agba Bisong, Ugwu Okechukwu Paul-Chima, Patrick Maduabuchi Aja
F1000Research | Journal Article
Crossref
2025
Gas Chromatography-Mass spectrometry (GC-MS) Revealed Bioactive Constituents of Brassica oleracea var. viridis (Collard Greens) Used to Treat Male Infertility in Uganda.
Emmanuel Orire Ikuomola, Daniel Udofia Owu, Victor Otu Oka, Sunday Agba Bisong, Ugwu Okechukwu Paul-Chima, Patrick Maduabuchi Aja
F1000Research | Journal Article
Crossref
2025
Blood pressure and ECG variables of healthy young males and females participating in moderate aerobic exercise
Idara Asuquo Okon, Justin Atiang Beshel, Albert E. Okorocha, Elijah Ekene Eze, Daniel U. Owu
Journal of Bodywork and Movement Therapies | Journal Article
Crossref
2024
Cardioprotective Effect of Peperomia pellucida against Doxorubicin-Induced Cardiotoxicity in Wistar Rats via Modulation of Electrocardiographic and Cardiac Biomarkers
Efiok Aniekan Archibong, Justin Atiang Beshel, Idara Asuquo Okon, Glory Aidam Ikum, Stella Chiamaka Anaba, Daniel Udofia Owu
Journal of Pharmacopuncture | Journal Article
Crossref
2024
Identification of Phytochemicals and Assessment of Hypoglycemic and Haematological Potentials of Terminalia catappa Linn leaf Extract in Alloxan-induced Diabetic Wistar Rats
Ezekiel E. Ben, Justin A. Beshel, Daniel U. Owu, Javier Palacios, Magdalene Nwokocha, Jorge Bórquez, Mario J. Simirgiotis, Chukwuemeka R. Nwokocha
Cardiovascular & Hematological Agents in Medicinal Chemistry | Journal Article
Crossref
2024
Cardioprotective Role of Theobroma cacao against Isoproterenol-Induced Acute Myocardial Injury
Justin Atiang Beshel, Favour Nyoh Beshel, Justina Nwandimma Nwangwa, Idara Asuquo Okon, Clement Ikani Ejim, Daniel Udofia Owu
Cardiovascular & Hematological Agents in Medicinal Chemistry | Journal Article
Crossref
2022
Gongronema latifolium leaf extract protects against dexamethasone‐induced myocardial cell injury via cardiac oxido‐inflammatory molecules modulation
Idara Asuquo Okon, Justin Atiang Beshel, Victor Udo Nna, Daniel Udofia Owu
Journal of Food Biochemistry | Journal Article
Crossref
2022
Ethanolic extract of Gongronema latifolium improves learning and memory in Swiss albino mice.
Ujong, G.O., J.A. Beshel, E. Nkanu, O.P. Ubana and O.E. Ofem,
J. Drug Delivery Ther., | Journal Article
Self Daniel Udofia Owu
2022
Anti-inflammatory potentials of ethanolic leaf extract of Gongronema latifolium in streptozotocin induced diabetic rats.
Ujong, G.O., J.A. Beshel, I.A. Okon and D.U. Owu,
World J. Bio. Pharm. Health Sci., | Journal Article
Self Daniel Udofia Owu
2022
Aqueous leaves extract of Telfairia occidentalis (Fluted Pumpkin) protects against gastric ulcer and inhibits intestinal motility in wistar rats.
Basse, I.O., I.A. Oko, J.A. Bes, E.B. Umo and D.U. Owu,
J. Appl. Sci., | Journal Article
Self Daniel Udofia Owu
2022
L-arginine oral supplementation reverses hematological and electrolytes imbalances in adrenaline-induced myocardial injury in rats.
Okon, I.A., J.A. Bes, I.S. Udoakag, J.P. Udia and D.U. Owu,
J. Med. Sci., | Journal Article
Self Daniel Udofia Owu
2022
Possible Amelioration of Oxidative Stress Damage Via Cyclo-Oxygenase Pathway by Aqueous Extract of Terminalia Catappa Leaves in Alloxan Induced Diabetic Rats.
Ben, E.E., A.E. Asuquo and D.U. Owu
GSC Biol. and Pharm. Sci. | Journal Article
Self Daniel Udofia Owu
2021
The Role of Serum Alpha-Amylase and Glycogen Synthase in the Anti-Diabetic Potential of Terminalia catappa Aqueous Leaf Extract in Diabetic Wistar Rats.
Ben, E.E., A.E. Asuquo and D.U. Owu
AJRIMPS | Journal Article
Self Daniel Udofia Owu
2019
Serum Levels of Some Inflammatory Markers in Alloxan- Induced Diabetic Rats Treated with Aqueous Leaf Extract of Terminalia catappa and Exogenous Insulin.
Ben, E.E., A.E. Asuquo and D.U. Owu
AJRIMPS | Journal Article
Self Daniel Udofia Owu
2019
Effect of Gongronema latifolium on lipid profile, oral glucose tolerance test and some hematological parameters in fructose-induced hyperglycemia in Wistar rats.
Okon, I.A., U.F. Ufot, U.G. Onoyeraye, E.O. Nwachukwu and D.U. Owu,
Pharm. Biomed. Res., | Journal Article
Self Daniel Udofia Owu
2019
Extra virgin olive oil and palm oil diets reduce blood pressure via Katp/Bkca ion channels in rats.
Nkanu, E.E., D.U. Owu and E.E. Osim,
J. Applied Sci., | Journal Article
Self Daniel Udofia Owu
2019
The effect of long term consumption of thermoxidised palm oil diet on some reproductive parameters in male Wistar rats.
Aribo, E.O., E.J. Ani, E.E. Osim and D.U. Owu,
World J. Pharmaceut. Res., | Journal Article
Self Daniel Udofia Owu
2018
Chronic consumption of Thermoxidized Palm Oil diet (TPO) adversely affects haemostatic status and histology of some organs in rabbit.
Ani, E.J., D.U. Owu, E.E. Osim and A.U. Ime,
Saudi J. Med. Pharmaceut. Sci., | Journal Article
Self Daniel Udofia Owu
2018
Altered potassium ion channel function as a possible mechanism of increased blood pressure in rats fed thermally oxidized palm oil diets.
Nkanu, E.E., D.U. Owu and E.E. Osim,
J. Dietary Suppl., | Journal Article
Self Daniel Udofia Owu
2018
Quercetin exerts preventive, ameliorative and prophylactic effects on cadmium chloride-induced oxidative stress in the uterus and ovaries of female Wistar rats.
Nna, V.U., U.Z. Usman, E.O. Ofutet and D.U. Owu,
Food Chem. Toxicol., | Journal Article
Self Daniel Udofia Owu
2017
Effect of vitamin C supplementation on platelet aggregation and serum electrolytes levels in streptozotocin-induced diabetes mellitus in rats.
Owu, D.U., C.R. Nwokocha, D.E. Ikpi and E.I. Ogar,
Niger. J. Physiol. Sci., | Journal Article
Self Daniel Udofia Owu
2016
Insulin and alpha amylase levels in alloxan-induced diabetic rats and the effect of Rothmannia hispida (K. Schum) Fagerl leaf extract.
Udia, P.M., L.P. Takem, U.F. Ufot, A.B. Antai and D.U. Owu,
J. Phytopharmacol., | Journal Article
Self Daniel Udofia Owu
2016
Distortions in sensitivity of carotid baroreceptor reflexes in rabbits following consumption of two forms of palm oil diets.
Ani, E.J., O.E. Ofem, D.U. Owu and E.E. Osim,
Br. J. Med. Med. Res., | Journal Article
Self Daniel Udofia Owu
2015
Possible mechanism of antispasmodic action of Garcinia kola seed extract on isolated Guinea pig ileum.
Udia, P.M., D.U. Owu, O.J. Ogbonna and L.P. Takem,
Br. J. Med. Med. Res., | Journal Article
Self Daniel Udofia Owu
2015
Sildenafil citrate and tramadol administered separately and in combination affects basal metabolic rate, triiodothyronine (T3) and cortisol levels in albino wistar rats.
Oka, V.O., A.L. Udefa, V.U. Nna and D.U. Owu,
Trends Med. Res., | Journal Article
Self Daniel Udofia Owu
2015
Effect of chronic consumption of two forms of palm oil diet on serum electrolytes, creatinine and urea in rabbits.
Ani, E.J., V.U. Nna, D.U. Owu and E.E. Osim,
J. Applied Pharma. Sci., | Journal Article
Self Daniel Udofia Owu
2015
A comparative study of the effect of some nutritional medicinal plants effect on lead accumulation in the liver following different modes of administration.
Nwokocha, C., N. Younger-Coleman, M. Nwokocha, D. Owu and M. Iwuala,
Pharmacogn. Res., | Journal Article
Self Daniel Udofia Owu
2014
Investigation of effects of time of measurement and modes of administration on cadmium accumulation in rat liver under some medicinal plants food supplemented diet.
Nwokocha, C.R., N. Younger-Coleman, M. Nwokocha, D.U. Owu and M. Iwuala,
Pharmacogn. Res., | Journal Article
Self Daniel Udofia Owu
2014
Anti-gastric ulcerative activity of Ocimum gratissimum in streptozotocin-induced diabetic rats.
Okon, U.A., A.O. Obembe, T.H. Olubobokun and D.U. Owu,
J. Scient. Res. Rep., | Journal Article
Self Daniel Udofia Owu
2013
Analysis of time of measurement and modes of administration of some medicinal plants additives on mercury accumulation in the liver.
Nwokocha, C.R., N. Younger-Coleman, M. Nwokocha, D.U. Owu, H. Asemota, M. Iwuala and A. Lay-Ekuakille,
Int. J. Meas. Technol. Instrum. Eng., | Journal Article
Self Daniel Udofia Owu
2013
Attenuated vascular responsiveness to K+ channel openers in diabetes mellitus: The differential role of reactive oxygen species.
Owu, D.U., N.N. Orie, C.R. Nwokocha, M. Muzyamba, L.H. Clapp and E.E. Osim,
Gen. Physiol. Biophys., | Journal Article
Self Daniel Udofia Owu
2013
Comparative effect of type 1 and type 2 diabetes mellitus on vascular responses of rat thoracic aorta to potassium ion channel openers.
Owu, D.U., N.N. Orie, C.R. Nwokocha, L.H. Clapp and E.E. Osim,
Br. J. Med. Med. Res., | Journal Article
Self Daniel Udofia Owu
2013
Gastric Ulceration in Diabetes Mellitus: Protective Role of Vitamin C
Daniel U. Owu, Agona O. Obembe, Chukwuemeka R. Nwokocha, Ime E. Edoho, Eme E. Osim
ISRN Gastroenterology | Journal Article
Crossref
2012
Possible mechanisms of action of the hypotensive effect of Annona muricata (soursop) in normotensive Sprague-Dawley rats.
Nwokocha, C.R., D.U. Owu, A. Gordon, K. Thaxter, G. McCalla, R.I. Ozolua and L. Young,
Pharmaceut. Biol., | Journal Article
Self Daniel Udofia Owu
2012
Possible mechanisms of action of the aqueous extract of Artocarpus altilis (breadfruit) leaves in producing hypotension in normotensive Sprague-Dawley rats.
Nwokocha, C.R., D.U. Owu, M. McLaren, J. Murray and R. Delgoda et al.,
Pharmaceut. Biol., | Journal Article
Self Daniel Udofia Owu
2012
Comparative analysis on the effect of Lycopersicon esculentum (tomato) in reducing cadmium, mercury and lead accumulation in liver.
Nwokocha, C.R., M.I. Nwokocha, I. Aneto, J. Obi and D.C. Udekweleze et al.,
Food Chem. Toxicol., | Journal Article
Self Daniel Udofia Owu
2012
In vivo distribution of lead in male and female rats after intraperitoneal and oral administration.
Nwokocha, C.R., C.S. Ufearo, D.U. Owu, N.C. Idemudo and L.C. Ojukwu,
Toxicol. Ind. Health, | Journal Article
Self Daniel Udofia Owu
2012
Comparative study on the hepatoprotection to heavy metals of Zingiber officinale.
Nwokocha, C.R., D.U. Owu, M.I. Nwokocha, C.S. Ufearo and M.O. Iwuala,
Pharmacogn. Res., | Journal Article
Self Daniel Udofia Owu
2012
Experimental malaria: The in vitro and in vivo blood pressure paradox.
Nwokocha, C.R., D.U. Owu, I.O. Ajayi, A.B. Ebeigbe and M.I. Nwokocha,
Cardiovasc. J. Afr., | Journal Article
Self Daniel Udofia Owu
2012
Comparative analysis on the effect of palm oil (Elaeis guineensis) in reducing cadmium and lead accumulation in liver of Wistar rats.
Nwokocha, C.R., M.I. Nwokocha, D.U. Owu, J. Obi and B. Olatunde et al.,
Pharmacogn. Res., | Journal Article
Self Daniel Udofia Owu
2012
Comparative study on the efficacy of Allium sativum (garlic) in reducing some heavy metal accumulation in liver of Wistar rats.
Nwokocha, C.R., D.U. Owu, M.I. Nwokocha, C.S. Ufearo and M.O.E. Iwuala,
Food Chem. Toxicol., | Journal Article
Self Daniel Udofia Owu
2012
Effect of Gongronema latifolium ethanol leaf extract on gastric acid secretion and cytoprotection in streptozotocin-induced diabetic rats.
Owu, D.U., C.R. Nwokocha, A.O. Obembe, A.D. Essien, D.E. Ikpi and E.E. Osim,
West Indian Med. J., | Journal Article
Self Daniel Udofia Owu
2012
Estimation of absorbed cadmium in tissues of male and female Albino rats through different routes of administration.
Nwokocha, C.R., M.I. Nwokocha, D.U. Owu, E. Edidjana, N. Nwogbo, U. Ekpo and C.S. Ufearo,
Niger. J. Physiol. Sci., | Journal Article
Self Daniel Udofia Owu
2011
Specificity of vascular reactivity and altered response in experimental malaria.
Nwokocha, C.R., I.O. Ajayi, D.U. Owu and A.B. Ebeigbe,
West Indian Med. J., | Journal Article
Self Daniel Udofia Owu
2011
Comparative study on the efficacy of Garcinia kola in reducing some heavy metal accumulation in liver of Wistar rats.
Nwokocha, C.R., D.U. Owu, C.S. Ufearo and M.O.E. Iwuala,
J. Ethnopharmacol., | Journal Article
Self Daniel Udofia Owu
2011
Antihypertensive properties of Allium sativum (garlic) on normotensive and two kidney one clip hypertensive rats.
Nwokocha, C.R., R.I. Ozolua, D.U. Owu, M.I. Nwokocha and A.C. Ugwu,
Niger J. Physiol. Sci., | Journal Article
Self Daniel Udofia Owu
2011
Bile secretion and palm oil diets in Wistar rats.
Obembe, A.O., A.B. Antai, D.U. Owu, O.O. Okwari, M.U. Eteng and E.E. Osim,
Nutr. Food Sci., | Journal Article
Self Daniel Udofia Owu
2010
Antispasmodic and spasmolytic effects of methanolic extract from seeds of Garcinia kola on isolated rat small intestine.
Udia, P.M., V.B. Braide and D.U. Owu,
Niger. J. Physiol. Sci., | Journal Article
Self Daniel Udofia Owu
2009
Effect of aqueous extract of Rothmannia hispida on gastric acid secretion and gastric mucosa protection (Cytoprotection).
Antai, A.B., D.U. Owu and O.E. Ofem,
Mary Slessor J. Med., | Journal Article
Self Daniel Udofia Owu
2008
Stimulation of gastric acid secretion and intestinal motility by Vernonia amygdalina extract.
Owu, D.U., E.E. Ben, A.B. Antai, E.A. Ekpe and P.M. Udia,
Fitoterapia, | Journal Article
Self Daniel Udofia Owu
2008
Intestinal motility and transit following chronic ingestion of different forms of palm oil diets.
Obembe, A.O., O.O. Okwari, D.U. Owu, A.B. Antai and E.E. Osim,
Nig. J. Physiol. Sci., | Journal Article
Self Daniel Udofia Owu
2008
Vitamin C improves basal metabolic rate and lipid profile in alloxan-induced diabetes mellitus in rats.
Owu, D.U., A.B. Antai, K.H. Udofia, A.O. Obembe, K.O. Obasi and M.U. Eteng,
J. Biosci., | Journal Article
Self Daniel Udofia Owu
2006
Effect of vitamin C on Serum lipids and electrolyte profile of Albino Wistar Rats.
Eteng, M.U., H.A. Ibekwe, T.E. Amatey, B.J. Bassey, F.U. Uboh and D.U. Owu,
Niger. J. Physiol. Sci., | Journal Article
Self Daniel Udofia Owu
2006
Lung function status of workers exposed to wood dust in timber markets in Calabar, Nigeria.
Okwari, O.O., A.B. Antai, D.U. Owu, E.J. Peters and E.E. Osim,
Afr. J. Med. Med. Sci., | Journal Article
Self Daniel Udofia Owu
2005
Effect of Bonny light crude oil on some haematological parameters of guinea pigs.
Owu, D.U., U.B. Udoete, N. Azah and E.U. Eyong,
Biokemistri, | Journal Article
Self Daniel Udofia Owu
2005
Effect of theobromine exposure on haematological parameters in rats.
Eteng, M.U., R.R. Ettarh and D.U. Owu,
Niger. J. Physiol. Sci., | Journal Article
Self Daniel Udofia Owu
2003
Contraction of the isolated guinea pig ileum induced by the crude extract from Eleophorbia drupifera leaves.
Eno, A.E., O.I. Owo, E.H. Itam, R.R. Ettarh, C.C. Mfem and D.U. Owu,
Global J. Pure Applied Sci., | Journal Article
Self Daniel Udofia Owu
1999
Haemolytic activity of the crude extract from Elaeophorbia drupifera leaves.
Eno, A.E., E.H. Itam, D.U. Owu, T. Ettrarh and R.S. Konya,
Biosci. Res. Commun., | Journal Article
Self Daniel Udofia Owu
1999
Influence of palm oil (Elaesis guineensis) on health.
Ebong, P.E., D.U. Owu and E.U. Isong,
Plant Food Human Nutr., | Journal Article
Self Daniel Udofia Owu
1999
Serum liver enzymes profile of Wistar rats following chronic consumption of fresh or oxidized palm oil diets.
Owu, D.U., E.E. Osim and P.E. Ebong,
Acta Tropica, | Journal Article
Self Daniel Udofia Owu
1998
Altered responses of isolated aortic smooth muscle following chronic ingestion of palm oil diets in rats.
Owu, D.U., E.E. Osim and N.N. Orie,
Afr. J. Med. Med. Sci., | Journal Article
Self Daniel Udofia Owu
1997
Arterial pressure and lipid profile in rats following chronic ingestion of palm oil diets.
Osim, E.E., D.U. Owu and K.M. Etta,
Afr. J. Med. Med. Sci., | Journal Article
Self Daniel Udofia Owu
1996
Influence of chronic consumption of thermoxidized and fresh palm oil diets on basal metabolic rate, body weight and morphology of tissues in rats.
Osim, E.E., D.U. Owu, E.U. Isong and I.B. Umoh,
Discovery Innov., | Journal Article
Self Daniel Udofia Owu
1994
Influence of chronic consumption of thermally oxidized palm oil diet on platelet aggregation in rats.
Osim, E.E., D.U. Owu, E. Isong and I.B. Umoh,
Discov. Innov. | Journal Article
Self Daniel Udofia Owu
1992