Ayodeji Folorunso Ajayi's LiveDNA Profile

IMMUNOINFORMATICS-BASED DESIGN OF A MULTI-EPITOPE ZIKA VIRUS VACCINE TARGETING ENVELOPE AND NS1 PROTEINS FOR ENHANCED HUMORAL AND CELLULAR IMMUNITY

Ayomide Jonathan Jegede, Ayodeji Folorunsho Ajayi, Oluwafemi Deborah Adesida, James Emmanuel Uchechukwu, Francisca Ayandamilola Ayantade, David Boluwatife Bankole, Yuunus Akeujolaade Abdulazeez, Paul Agbaraoluwa Oyeleke, Ayomide David Ojo

Next Research | Journal Article

10.1016/j.nexres.2026.102424

2026

Vitamin D3 attenuates methamphetamine-induced oxidative stress, neurochemical alterations, and neuronal damage in male Wistar rats

Ayodeji Folorunsho Ajayi, Ayomide Jonathan Jegede, Oyedayo Phillips Akano, Toluwalope Oluwafisayo Iyiola

Biomarkers in Neuropsychiatry | Journal Article

10.1016/j.bionps.2026.100142

2026

Omega-3 fatty acids mitigate methamphetamine-induced reproductive toxicity in rats through redox homeostasis, anti-inflammatory modulation, and steroidogenic support

Florence Bukola Adisa, Oyedayo Phillips Akano, David Tolulope Oluwole, Moses Agbomhere Hamed, Ayodeji Folorunsho Ajayi

Pharmacological Research - Reports | Journal Article

10.1016/j.prerep.2026.100093

2026

Effects of coenzyme Q10 on sexual behavior and hormonal profiles in male rats treated with trihexyphenidyl

Lateef Olabisi Okeleji, Ayoola Isaac Jegede, Ayodeji Folorunsho Ajayi

Pharmacological Research - Natural Products | Journal Article

10.1016/j.prenap.2025.100469

2026

Climate-induced migration: A growing concern for global food security and nutrition

Victor Temitope Aremu, Bernard Opeyemi Adedeji, Taiwo Kayode Ojediran, Ayodeji Folorunsho Ajayi

Food and Humanity | Journal Article

10.1016/j.foohum.2025.100954

2026

Glutathione as a Potential Neuroprotectant Against MDMA-Induced Oxidative Stress, Neuroinflammation, and Apoptosis in the Rat Brain

Oyedayo Phillips Akano, Goodness Olatinwo, Moses Agbomhere Hamed, David Tolulope Oluwole, Ayomide Jonathan Jegede, Ayodeji Folorunsho Ajayi

Neurochemical Research | Journal Article

10.1007/s11064-026-04764-0

2026

Omega-3 attenuates codeine-induced hepatic injury in female wistar rats via its antioxidative, anti-inflammatory, and anti-apoptotic effects

Ayodeji Folorunsho Ajayi, Alimat Toyin Lawal, Deborah Adeola Oke, Moses Agbomhere Hamed, Lydia Oluwatoyin Ajayi, Oladipupo Samuel Ebiwonjumi, David Tolulope Oluwole

Pharmacological Research - Natural Products | Journal Article

10.1016/j.prenap.2026.100617

2026

The role of nanotechnology in male fertility assessment

Ayodeji Folorunsho Ajayi, Ayomide Jonathan Jegede, Ubong Edem David, Olaniyi Azeez Soetan, Lateef Olabisi Okeleji

Next Nanotechnology | Journal Article

10.1016/j.nxnano.2025.100360

2026

Vitamin D3, cholecalciferol via its hydroxylmetabolites, receptors and metabolizing enzymes modulates male reproductive functions

David Tolulope Oluwole, Ayodeji Folorunsho Ajayi

Life Sciences | Journal Article

10.1016/j.lfs.2025.123680

2025

Epigenetics’ responsibility in endometriosis: A comprehensive assessment

Oyedayo Phillips Akano, Victor Oluwaloseyi Amos, Israel Opeyemi Fawole, Adewole Christianah Oyindamola, Ayodeji Folorunsho Ajayi

The Journal of Steroid Biochemistry and Molecular Biology | Journal Article

10.1016/j.jsbmb.2025.106814

2025

Protective effects of coenzyme Q10 against trihexyphenidyl-induced testicular oxidative damage: modulation of antioxidant enzymes, inflammatory markers, hormonal and steroidogenic pathways in rats

Lateef Olabisi Okeleji, Moses Agbomhere Hamed, Ayoola Isaac Jegede, Mega Obukohwo Oyovwi, Ayodeji Folorunsho Ajayi

Steroids | Journal Article

10.1016/j.steroids.2025.109664

2025

Beetroot Fruit Powder Attenuates Cardiotoxicity Induced by Monosodium Glutamate via Inhibition of Oxidative Stress and Inflammation in Rats

Blessing Oluwapelumi Oyebamiji, Moshood Abiola Folawiyo, Blessing Tolulope Owolabi, Ayodeji Folorunsho Ajayi

Australian Journal of Biomedical Research | Journal Article

10.63946/aubiomed/17520

2025

Bacterial Zoonotic Diseases and Male Reproduction

Lateef Olabisi Okeleji, Lydia Oluwatoyin Ajayi, Aduragbemi Noah Odeyemi, Victor Amos, Bosede Grace Akanbi, Moyinoluwa Comfort Onaolapo, Bolade Sylvester Olateju, Wale Johnson Adeyemi, Ayodeji Folorunsho Ajayi

Zoonotic Diseases | Journal Article

10.3390/zoonoticdis4010010

2024

A review on available proteomic databases, annotation techniques and data projects important in male reproductive physiology research

Ayodeji Folorunsho Ajayi, Lateef Olabisi Okeleji, Oluwadunsin Iyanuoluwa Adebayo, Emmanuel Tayo Adebayo, Victor Amos, Lydia Oluwatoyin Ajayi, Bolaji Aderibigbe Akorede, Ashraf Akintayo Akintola

Journal of Proteins and Proteomics | Journal Article

10.1007/s42485-024-00144-w

2024

Harnessing Immunoinformatics for Precision Vaccines: Designing Epitope-Based Subunit Vaccines against Hepatitis E Virus

Elijah Kolawole Oladipo, Emmanuel Oluwatobi Dairo, Comfort Olukemi Bamigboye, Ayodeji Folorunsho Ajayi, Olugbenga Samson Onile, Olumuyiwa Elijah Ariyo, Esther Moradeyo Jimah, Olubukola Monisola Oyawoye, Julius Kola Oloke, Bamidele Abiodun Iwalokun, Olumide Faith Ajani, Helen Onyeaka

BioMedInformatics | Journal Article

10.3390/biomedinformatics4030088

2024

Lecithin and cardiovascular health: a comprehensive review

Moyinoluwa Comfort Onaolapo, Olubunmi Dupe Alabi, Oyedayo Phillips Akano, Bolade Sylvester Olateju, Lateef Olabisi Okeleji, Wale Johnson Adeyemi, Ayodeji Folorunsho Ajayi

The Egyptian Heart Journal | Journal Article

10.1186/s43044-024-00523-0

2024

Physiological responses of Lizard, Toad and Pigeon during rainy season in tropical savanna climate

Ayodeji Folorunsho Ajayi, Oluwadare Joshua Ogundipe, Lukman Olawale Ajayi, Abiodun Oyerinde, Omolola Funke Akinpelu

The Journal of Basic and Applied Zoology | Journal Article

10.1186/s41936-024-00396-4

2024

Catechin from Anonna senegalensis is a Potential Inhibitor of Erectile Dysfunction: Implication for Its Use in Male Sexual Enhancement

Moshood Abiola Folawiyo, Idowu Olamiposi Omotuyi, Folashade Omobolanle Ajao, Elizabeth Besong, Temitope Isaac Adelusi, Ayodeji Folorunsho Ajayi

Applied Biochemistry and Biotechnology | Journal Article

10.1007/s12010-023-04557-z

2023

Upregulation of Uric Acid Production and Caspase 3 Signalling Mediates Rohypnol-Induced Cardiorenal Damage

R. E. Akhigbe, A. A. Oladipo, P. A. Oyedokun, M. A. Hamed, L. O. Okeleji, A. F. Ajayi

Cardiovascular Toxicology | Journal Article

10.1007/s12012-022-09723-z

2022

Codeine alters female reproductive function by targeting ovarian steroidogenesis and folliculogenesis via the induction of oxidative stress, inflammation, and apoptosis

R.E. Akhigbe, O.S. Ebiwonjumi, L.O. Ajayi, A.F. Ajayi

Reproductive Toxicology | Journal Article

10.1016/j.reprotox.2022.02.001

2022

L-Arginine reverses maternal and pre-pubertal codeine exposure-induced sexual dysfunction via upregulation of androgen receptor gene and NO/cGMP signaling

Roland Eghoghosoa Akhigbe, Oladele A. Afolabi, Ayodeji F. Ajayi

PLOS ONE | Journal Article

10.1371/journal.pone.0274411

2022

Viral Zoonotic Diseases of Public Health Importance and Their Effect on Male Reproduction

Olabisi Lateef Okeleji, Lydia Oluwatoyin Ajayi, Aduragbemi Noah Odeyemi, Victor Amos, Hezekiah Oluwatobi Ajayi, Amos Olalekan Akinyemi, Chibueze Samuel Nzekwe, Johnson Wale Adeyemi, Ayodeji Folorunsho Ajayi

Zoonotic Diseases | Journal Article

10.3390/zoonoticdis2040023

2022

Anti-atherogenic and cardio-protective properties of sweet melon (Cucumis melo. L. Inodorus) seed extract on high fat diet induced obesity in male wistar rats

G. Adebayo-Gege, V. Alicha, T. O. Omayone, S. C. Nzekwe, C. A. Irozuoke, O. A. Ojo, A. F. Ajayi

BMC Complementary Medicine and Therapies | Journal Article

10.1186/s12906-022-03793-w

2022

Rohypnol‐induced sexual dysfunction is via suppression of hypothalamic‐pituitary‐testicular axis: An experimental study in rats

David Tolulope Oluwole, Roland Eghoghosoa Akhigbe, Ayodeji Folorunsho Ajayi

Andrologia | Journal Article

10.1111/and.13931

2021

Oxidative Stress and Cardiometabolic Disorders

Roland E. Akhigbe, Ayodeji F. Ajayi, Sahu K. Ram

BioMed Research International | Journal Article

10.1155/2021/9872109

2021

The impact of reactive oxygen species in the development of cardiometabolic disorders: a review

Roland Akhigbe, Ayodeji Ajayi

Lipids in Health and Disease | Journal Article

10.1186/s12944-021-01435-7

2021

Hsps70 and 90 protect the heart of hyperthyroid rats via nitric oxide production and VEGF inhibition of apoptosis

Ayodeji Folorunsho Ajayi, Olubodun Micheal Lateef, Oluwadunsi Iyanuoluwa Adebayo, Emmanuel Tayo Adebayo

Endocrine and Metabolic Science | Journal Article

10.1016/j.endmts.2021.100097

2021

Phyllanthus amarus attenuated derangement in renal-cardiac function, redox status, lipid profile and reduced TNF-α, interleukins-2, 6 and 8 in high salt diet fed rats

Olubukola Sinbad Olorunnisola, Olumide Samuel Fadahunsi, Peter Ifeoluwa Adegbola, Bamidele Stephen Ajilore, Folorunsho Ayodeji Ajayi, Lamidi Waheed Babatunde Olaniyan

Heliyon | Journal Article

10.1016/j.heliyon.2021.e08106

2021

Codeine-induced hepatic injury is via oxido-inflammatory damage and caspase-3-mediated apoptosis

R. E. Akhigbe, L. O. Ajayi, A. A. Adelakun, O. S. Olorunnisola, A. F. Ajayi

Molecular Biology Reports | Journal Article

10.1007/s11033-020-05983-6

2020

Exploration of surface glycoprotein to design multi-epitope vaccine for the prevention of Covid-19

Elijah Kolawole Oladipo, Ayodeji Folorunsho Ajayi, Olumuyiwa Elijah Ariyo, Samson Olugbenga Onile, Esther Moradeyo Jimah, Louis Odinakaose Ezediuno, Oluwadunsin Iyanuoluwa Adebayo, Emmanuel Tayo Adebayo, Aduragbemi Noah Odeyemi, Marvellous Oluwaseun Oyeleke, Moyosoluwa Precious Oyewole, Ayomide Samuel Oguntomi, Olawumi Elizabeth Akindiya, Bunmi Olayemi Olamoyegun, Victoria Oyetayo Aremu, Abiola O. Arowosaye, Dorcas Olubunmi Aboderin, Habibat Bolanle Bello, Tosin Yetunde Senbadejo, Elukunbi Hilda Awoyelu, Adio Abayomi Oladipo, Bukola Bisola Oladipo, Lydia Oluwatoyin Ajayi, Olusola Nathaniel Majolagbe, Olubukola Monisola Oyawoye, Julius Kola Oloke

Informatics in Medicine Unlocked | Journal Article

10.1016/j.imu.2020.100438

2020

Testicular toxicity following chronic codeine administration is via oxidative DNA damage and up-regulation of NO/TNF-α and caspase 3 activities

Roland Akhigbe, Ayodeji Ajayi

PLOS ONE | Journal Article

10.1371/journal.pone.0224052

2020

Staging of the estrous cycle and induction of estrus in experimental rodents: an update

Ayodeji Folorunsho Ajayi, Roland Eghoghosoa Akhigbe

Fertility Research and Practice | Journal Article

10.1186/s40738-020-00074-3

2020

The physiology of male reproduction: Impact of drugs and their abuse on male fertility

Ayodeji Folorunsho Ajayi, Roland Eghoghosoa Akhigbe

Andrologia | Journal Article

10.1111/and.13672

2020

Codeine-induced sperm DNA damage is mediated predominantly by oxidative stress rather than apoptosis.

Ajayi, A.F. and R.E. Akhigbe,

Redox Rep., | Journal Article

10.1080/13510002.2020.1752003

Ayodeji Folorunso Ajayi

2020

Immunohistochemical studies of age-related changes in cell proliferation and angiogenesis during the healing of acetic acid-induced gastric ulcers in rats.

Ajayi, A.F. and S.B. Olaleye,

Sci. World J., | Journal Article

10.1155/2020/3506207

Ayodeji Folorunso Ajayi

2020

Laboratory diagnosis of COVID-19 in Africa: availability, challenges and implications.

Oladipo, E.K., A.F. Ajayi, A.N. Odeyemi, O.E. Akindiya and E.T. Adebayo et al.,

Drug Discoveries Ther., | Journal Article

10.5582/ddt.2020.03067

Ayodeji Folorunso Ajayi

2020

Age-related changes in haematological parameters and biochemical markers of healing in the stomach of rats with acetic acid induced injury.

Ajayi, A.F. and B.S. Olaleye,

Toxicol. Rep., | Journal Article

10.1016/j.toxrep.2020.09.007

Ayodeji Folorunso Ajayi

2020

Replacement value of cassava vinasse meal for maize on growth performance, haematological parameters and organoleptic properties of japanese quails (Coturnix japonica).

Ojediran, T.K.,

Acta fytotechnica zootechnica, | Journal Article

10.15414/afz.2019.22.01.7-12

Ayodeji Folorunso Ajayi

2019

Effect of thyroxine and carbimazole treatments on basal and histamine stimulated gastric acid secretion in the common African toad (Bufo regularis).

Folorunsho, A.A. and O.S. Babafemi,

Egypt. J. Aquat. Biol. Fish., | Journal Article

10.21608/ejabf.2019.52174

Ayodeji Folorunso Ajayi

2019

Effects of processing methods and levels of inclusion of Jatropha curcas kernel meal on performance, organ characteristics, haematology and serum chemistry of finisher broiler chickens.

Ojediranemiola, T., A. Ajayi and A. Isiak,

J. Agric. Sci., Belgrade, | Journal Article

10.2298/jas1901069o

Ayodeji Folorunso Ajayi

2019

Assessment of sexual behaviour and fertility indices in male rabbits following chronic codeine use.

Ajayi, A.F. and R.E. Akhigbe,

Andrology, | Journal Article

10.1111/andr.12717

Ayodeji Folorunso Ajayi

2019

Synergistic and ameliorative effect of honey and coconut water on crude oil induced toxicity in rats.

Akintola, A.O., B.D. Kehinde, J.O. Fakunle and A.F. Ajayi,

Res. J. Environ. Toxicol., | Journal Article

10.3923/rjet.2018.24.33

Ayodeji Folorunso Ajayi

2018

Anti-diabetic and antioxidant potentials of aqueous extract of Eucalyptus globulus in experimentally-induced diabetic rats.

Saka W.A., R.E. Akhigbe, A.F. Ajayi, L.O. Ajayi and O.E. Nwabuzor

Afr. J. Trad., Compl. Alt. Med., | Journal Article

10.21010/ajtcam.v14i6.3

Ayodeji Folorunso Ajayi

2017

Activation of cardiac TNF-α in altered thyroid state-induced cardiometabolic disorder.

Ajayi, A.F., R.E. Akhigbe and L.O. Ajayi,

J. Cardiovasc. Dis. Res., | Journal Article

10.5530/jcdr.2017.4.33

Ayodeji Folorunso Ajayi

2017

Antispermatogenic mechanism of trona is associated with lipid peroxidation but not testosterone suppression.

Ajayi, A.F. and R.E. Akhigbe,

J. Hum. Reprod. Sci., | Journal Article

10.4103/jhrs.JHRS_104_16

Ayodeji Folorunso Ajayi

2017

Ulcer healing mechanism of ethanolic extract of Talinium triangulare in male wistar rats.

Ajayi, A.F., A.B. Folawiyo and T.A. Salami,

UK J. Pharm. Biosci., | Journal Article

10.20510/ukjpb/4/i4/110647

Ayodeji Folorunso Ajayi

2016

Trona causes foetal loss in pregnant rats via an oestrogen-dependent mechanism.

Ajayi, A.F. and R.E. Akhigbe,

West Indian Med. J., | Journal Article

10.7727/wimj.2014.254

Ayodeji Folorunso Ajayi

2016

Age-related changes in the response of the rat gastric mucosa to acetic acid-and indomethacin-induced ulceration.

Ajayi, A.F. and S.B. Olaleye,

Arch. Bas. App. Med., | Journal Article

Ayodeji Folorunso Ajayi

2015

Toxicological and biochemical studies of ethanolic fruit extract of Adenopus breviflorus (Lagenaria breviflora Roberty) in male albino wistar rats.

Balogun, M.E., A.F. Ajayi, O.J. Oji, E.E. Besong, E. Finbarrs-Bello and M.A. Folawiyo,

Am. J. Phytomedicine Clin. Ther., | Journal Article

Ayodeji Folorunso Ajayi

2014

Ethanolic extract of Blighia sapida improved male wistar rats reproductivevariables.

Ajayi, A.F. and L.O. Ajayi,

Res. J. Med. Sci., | Journal Article

Ayodeji Folorunso Ajayi

2014

Hypothalamic-pituitary-ovarian axis in thyroid dysfunction.

Ajayi, A.F., R.E. Akhigbe and L.O. Ajayi,

West Indian Med. J., | Journal Article

10.7727/wimj.2013.038

Ayodeji Folorunso Ajayi

2013

Reproductive profile of male wistar rats treated with graded doses of aqueous extract of Titonia diversifolia leaf.

Ajayi, A.F. and A.I. Jegede,

World J. Life Sci. Med. Res., | Journal Article

Ayodeji Folorunso Ajayi

2012

Implication of altered thyroid state on liver function.

Ajayi, A.F. and R.E. Akhigbe,

Thyroid. Res., | Journal Article

10.4103/0973-0354.99649

Ayodeji Folorunso Ajayi

2012

Effect of ethanolic extract of Cryptolepis sanguinolenta stem on in vivo and in vitro glucose absorption and transport: Mechanism of its antidiabetic activity.

Ajayi, A.F., R.E. Akhigbe, O.M. Adewumi, L.O. Okeleji, K.B. Mujaidu and S.B. Olaleye,

Indian J. Endocr. Metab., | Journal Article

10.4103/2230-8210.94265

Ayodeji Folorunso Ajayi

2012

Antifertility activity of Cryptolepis sanguinolenta leaf ethanolic extract in male rats.

Ajayi, A.F. and R.E. Akhigbe,

J. Hum. Reprod. Sci., | Journal Article

10.4103/0974-1208.97799

Ayodeji Folorunso Ajayi

2012

Haematological and serum biochemical indices of pre-pubertal male rabbits fed with graded level of blood-wild sunflower forage meal mixture.

Ajayi, A.F. and Y. Raji,

Afr. J. Biotechnol., | Journal Article

10.5897/AJB10.2169

Ayodeji Folorunso Ajayi

2012

Gastric secretagogue action of Cryptolepis sanguinolenta in the perfused stomach of anesthetized rats.

Ajayi, A.F., R.E. Akhigbe, T.O. Iyiola, O.M. Adewumi and S.B. Olaleye,

Int. J. Med. Biomed. Res., | Journal Article

Ayodeji Folorunso Ajayi

2012

Haematological evaluation of Cryptolepis sanguinolenta stem ethanolic extract in rats.

Ajayi, A.F., R.E. Akhigbe, O.M. Adewumi and S.B. Olaleye,

Int. J. Med. Biomed. Res., | Journal Article

Ayodeji Folorunso Ajayi

2012

Hepatoprotective effect of Allium cepa in cadmium-treated rat.

Ige, S.F., R.E. Akhigbe, O. Edeogho, F.O. Ajao, O.Q. Owolabi, O.S. Oyekunle and A.F. Ajayi,

Int. J. Pharm. Pharm. Sci., | Journal Article

Ayodeji Folorunso Ajayi

2011

Caudal epididymal sperm characteristics and testicular morphometrics of rabbits fed graded levels of blood-wild sunflower leaf meal (BWSLM) mixture diet.

Ajayi, A.F., Y. Raji, V.O. Togun and A.O. Oyewopo,

J. Complementary Integr. Med., | Journal Article

10.2202/1553-3840.1232

Ayodeji Folorunso Ajayi

2009

Anti-hyperglycemic and hypolipidemic effect of ethanolic extract of Chrysophyllum albidum seed cotyledon in alloxan induced-diabetic rats.

Ajayi, A.F., L.O. Ehigie, O.S. Olorunnisola and S. Amao,

Res. J. Applied Sci., | Journal Article

10.3923/rjasci.2008.123.127

Ayodeji Folorunso Ajayi

2008

Water balance and serum levels of some electrolytes in oral contraceptive-treated female wistar rats.

Akhigbe, R.E., S.F. Ige, A.O. Afolabi, P.I. Oyeyipo, F.O. Ajao and F.A. Ajayi,

J. Med. Sci., | Journal Article

10.3923/jms.2008.591.594

Ayodeji Folorunso Ajayi

2008

Growth performance of male rabbit fed diets containing varying energy levels.

Ojebiyi, O.O., G.O. Farinu, A.F. Ajayi, J.A. Akinlade, O.O. Odunsi and I.A. Emiola,

Niger. J. Anim. Sci., | Journal Article

Ayodeji Folorunso Ajayi

2007

Performance evaluation of male weaner rabbits fed diets containing graded levels of Blood-wild sunflower leaf meal mixture.

Ajayi, A.F., G.O. Farinu, O.O. Oyebiyi and T.B. Olayemi,

World J. Agric. Sci., | Journal Article

Ayodeji Folorunso Ajayi

2007

Replacement of GNC and maize with Falderbia Albida (Gao) in the diet of broiler chicks.

Olorode, B.R., A.F. Ajayi,

Bull. Anim. Health Prod. Afr. Kenya, | Journal Article

Ayodeji Folorunso Ajayi

2005

Ayodeji Folorunso Ajayi

Education

Publications (65)