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Franklyn Nonso Iheagwam

Franklyn Nonso Iheagwam

LiveDNA ID: 234.18474
41 Publications
0 Editorial Roles
0 Projects

Education

Academic Background
  • Ph.D. Covenant University, Ota, Nigeria Biochemistry and Molecular Biology | Completed: 2020

Publications (41)

Selected Scholarly Contributions
COVID-19 and Diabetic Ketoacidosis Comorbidity: A Hand-in-Palm Occurrence
Franklyn Nonso Iheagwam, Esther Ogheneyoma Avwaghwaruvwe, Shalom Nwodo Chinedu
Proceedings of the National Academy of Sciences, India Section B: Biological Sciences | Journal Article
Crossref
2026
Nutraceutical potential of palm oil: Molecular targets and bioinformatics evaluation of constituents against type 2 diabetes mellitus
Franklyn Nonso Iheagwam, Timothy Oluwatimileyin Ayeni, Gbolahan Oladipupo Oduselu
In Silico Research in Biomedicine | Journal Article
Crossref
2026
Multiomic analyses of longitudinal plasma samples identify thromboinflammation endotypes and trajectories in patients with trauma
Mitchell J. Cohen, Christopher B. Erickson, Ian S. Lacroix, Margot Debot, Monika Dzieciatkowska, Sanchayita Sen, Terry R. Schaid, Lauren T. Gallagher, William M. Hallas, Otto N. Thielen, Alexis L. Cralley, Benjamin W. Stocker, Benjamin J. Ramser, Ava Mokhtari, Huma Baig, Christopher Sublette, Franklyn Iheagwam, Alyssa Caldwell-McGee, Jamie Cole, Kelly Nash, Marissa Pokharel, Jessica C. Cardenas, Anirban Banerjee, Ernest E. Moore, Christopher C. Silliman, Alan Hubbard, Angelo D’Alessandro, Kirk C. Hansen
Science Translational Medicine | Journal Article
Crossref
2026
Mitochondrial Dysfunction in Diabetes: Shedding Light on a Widespread Oversight
Franklyn Nonso Iheagwam, Amarachi Joy Joseph, Eniola Deborah Adedoyin, Olawumi Toyin Iheagwam, Samuel Akpoyowvare Ejoh
Pathophysiology | Journal Article
Crossref
2025
Diabetes mellitus: The pathophysiology as a canvas for management elucidation and strategies
Franklyn Nonso Iheagwam, Olawumi Toyin Iheagwam
Medicine in Novel Technology and Devices | Journal Article
Crossref
2025
Radical scavenging, anti-inflammatory and glucose metabolising enzymes activity of Secamone afzelii K. leaf and vine: In vitro and in silico studies
Franklyn Nonso Iheagwam, Gloria Aniedi Itina, Oyinkansola Ayobolanle Faluyi, Olawumi Toyin Iheagwam
Pharmacological Research - Natural Products | Journal Article
Crossref
2025
Steroid 5α-Reductase 2 Single Nucleotide Polymorphism Modulation of Phytosterol Binding Efficiency: An In silico Approach
Franklyn Nonso Iheagwam, Timothy Oluwatimileyin Ayeni, Shalom Nwodo Chinedu
Chemistry Africa | Journal Article
Crossref
2025
Apicoplast-Resident Processes: Exploiting the Chink in the Armour of Plasmodium falciparum Parasites
Collins Ojonugwa Mamudu, Mercy Eyitomi Tebamifor, Mary Ohunene Sule, Titilope Modupe Dokunmu, Olubanke Olujoke Ogunlana, Franklyn Nonso Iheagwam
Advances in Pharmacological and Pharmaceutical Sciences | Journal Article
Crossref
2024
Changes in nutritional, health benefits, and pharmaceutical potential of raw and roasted tropical almond (Terminalia catappa Linn.) nuts from Nigeria
Ifeoma Felicia Chukwuma, Emmanuel Chekwube Ossai, Florence Nkechi Nworah, Victor Onukwube Apeh, Emmanuel Osinachi Abiaziem, Franklyn Nonso Iheagwam, Hanna Skendrović, Szymon Juchniewicz, Katarzyna Leicht, Charles Odilichukwu R. Okpala, Małgorzata Korzeniowska
PLOS ONE | Journal Article
Crossref
2024
LEVERAGING THE SUCCESS OF MRNA LIPID NANOPARTICLE VACCINE IN COVID-19 TREATMENT: A NARRATIVE REVIEW ON ITS POTENTIAL APPLICATION IN MALARIA TREATMENT
FRANKLYN NONSO IHEAGWAM, ENIOLA DEBORAH ADEDOYIN
International Journal of Applied Pharmaceutics | Journal Article
Crossref
2024
High eggplant (Solanum aethiopicum L.) fruit intake for short duration enhances the antioxidant activity and biochemical parameters in rats
Franklyn Nonso Iheagwam, Shalom Nwodo Chinedu
Journal of Phytology | Journal Article
Crossref
2024
Anti-Obesity Potential of Secamone afzelii K. Leaf and Vine Ethanol Extract: Insights into Lipase Inhibition and Secondary Metabolites
Franklyn Nonso Iheagwam, Gloria Aniedi Itina, Oyinkansola Ayobolanle Faluyi, Mercy Bella-Omunagbe, Samuel Akpoyowvare Ejoh
Sci | Journal Article
Crossref
2024
Counteractive role of Terminalia catappa leaf extract on hematological and coagulation disturbance in Type 2 diabetic rats
Franklyn Nonso Iheagwam, Precious Amaneshi Garuba, Olubanke Olujoke Ogunlana, Shalom Nwodo Chinedu
Veterinary World | Journal Article
Crossref
2023
Terminalia catappa Leaf Abrogates Diabetes-induced Dyslipidaemia in Type 2 Diabetic Rats by Upregulating Lipid Metabolic Genes
Franklyn Nonso Iheagwam, Olawumi Toyin Iheagwam, Olubanke Olujoke Ogunlana, Shalom Nwodo Chinedu
Gene Expression | Journal Article
Crossref
2023
Nutritional, Phytochemical, and Biological Activities of Chrysophyllum albidum Fruit Extracts from Lagos
Ngozi Awa Imaga, Franklyn Nonso Iheagwam, Edidiong Urua, Evarista Ayodele Ebigwai
The Scientific World Journal | Journal Article
Crossref
2023
Stage 2 Hypertension and Electrocardiogram Abnormality: Evaluating the Risk Factors of Cardiovascular Diseases in Nigeria
Shalom Nwodo Chinedu, Franklyn Nonso Iheagwam, Michael Kemjika Onuoha, Grace Nkechi Joshua, Opeyemi Christianah DeCampos
High Blood Pressure & Cardiovascular Prevention | Journal Article
Crossref
2022
Toxicological profile of Dacryodes edulis (G. Don.) H. J. Lam. and Persea americana M. seeds in male Wistar rats
Franklyn Nonso Iheagwam, Blessing Chioma Onyido, Shalom Nwodo Chinedu
Comparative Clinical Pathology | Journal Article
Crossref
2022
In Vitro Experimental Assessment of Ethanolic Extract of Moringa oleifera Leaves as an α-Amylase and α-Lipase Inhibitor
Adebanke Ogundipe, Babatunde Adetuyi, Franklyn Iheagwam, Keleko Adefoyeke, Joseph Olugbuyiro, Oluseyi Ogunlana, Olubanke Ogunlana
Biochemistry Research International | Journal Article
Crossref
2022
Correction to: Stage 2 Hypertension and Electrocardiogram Abnormality: Evaluating the Risk Factors of Cardiovascular Diseases in Nigeria
Shalom Nwodo Chinedu, Franklyn Nonso Iheagwam, Michael Kemjika Onuoha, Grace Nkechi Joshua, Opeyemi Christianah DeCampos
High Blood Pressure & Cardiovascular Prevention | Journal Article
Crossref
2022
Antidiabetic modulatory effects of Vernonia amygdalina and Allium sativum combined extract in streptozotocin-induced diabetic rats
Ngozi Awa Imaga, Franklyn Nonso Iheagwam, Comfort Asibe, Temiloluwa Boluwatife Sogunle, Shalom Nwodo Chinedu
Vegetos | Journal Article
Crossref
2022
Type 2 Diabetes Mellitus Mediation by the Disruptive Activity of Environmental Toxicants on Sex Hormone Receptors: In Silico Evaluation
Franklyn Nonso Iheagwam, Joseph Kelechi Odiba, Olawumi Toyin Iheagwam, Olubanke Olujoke Ogunlana, Shalom Nwodo Chinedu
Toxics | Journal Article
Crossref
2021
Terminalia catappa Extract Palliates Redox Imbalance and Inflammation in Diabetic Rats by Upregulating Nrf-2 Gene
Franklyn Nonso Iheagwam, Gaber El-Saber Batiha, Olubanke Olujoke Ogunlana, Shalom Nwodo Chinedu
International Journal of Inflammation | Journal Article
Crossref
2021
Potassium Dichromate-Induced Hepato- and Hematotoxicity in Rats: Nutritive Composition and Ameliorative Role of Acacia nilotica L. Leaf
Samuel Akpoyowvare Ejoh, Franklyn Nonso Iheagwam, Afolabi Olakunle Olusola
Jundishapur Journal of Natural Pharmaceutical Products | Journal Article
Crossref
2021
Toxicopathological, proinflammatory and stress response evaluation of Terminalia catappa extract in male wistar rats.
Iheagwam, F.N., C.O. Okeke, O.C.D. Campos, B.E. Adegboye, O.O. Ogunlana and S.N. Chinedu,
Toxicol. Rep., | Journal Article
Self Franklyn Nonso Iheagwam
2021
Phytochemical composition, antioxidant activity and toxicity of aqueous extract of Picralima nitida in Drosophila melanogaster.
Campos, O.C.D., M.P. Layole, F.N. Iheagwam, S.O. Rotimi, S.N. Chinedu,
Trop. J. Nat. Prod. Res., | Journal Article
Self Franklyn Nonso Iheagwam
2021
Effect of aqueous extract of Momordica charantia on survival, locomotive behaviour and antioxidant status of drosophila melanogaster.
De-Campos, O.C., M.P. Layole, F.N. Iheagwam, S.O. Rotimi and S.N. Chinedu,
Trop. J. Nat. Prod. Res., | Journal Article
Self Franklyn Nonso Iheagwam
2021
Cytotoxic assessment of Xylopia aethiopica [dun.] a. on human prostate and breast cancer cell lines.
Iweala, E.E.J., E.O. Bankole, F.N. Iheagwam, O.E. Dania, U.F. Ntite,
Trop. J. Nat. Prod. Res., | Journal Article
Self Franklyn Nonso Iheagwam
2021
Anti‐inflammatory Mechanism of Ruzu Bitters on Diet‐Induced Nonalcoholic Fatty Liver Disease in Male Wistar Rats
Olubanke O. Ogunlana, Oluseyi E. Ogunlana, Tobi S. Adekunbi, Babatunde O. Adetuyi, Bose E. Adegboye, Franklyn N. Iheagwam
Evidence-Based Complementary and Alternative Medicine | Journal Article
Crossref
2020
Nauclea latifolia Sm. Leaf Extracts Extenuates Free Radicals, Inflammation, and Diabetes-Linked Enzymes
Franklyn Nonso Iheagwam, Emmanuel Nsedu Israel, Kazeem Oyindamola Kayode, Opeyemi Christianah DeCampos, Olubanke Olujoke Ogunlana, Shalom Nwodo Chinedu
Oxidative Medicine and Cellular Longevity | Journal Article
Crossref
2020
Computer-Aided Analysis of Multiple SARS-CoV-2 Therapeutic Targets: Identification of Potent Molecules from African Medicinal Plants
Franklyn Nonso Iheagwam, Solomon Oladapo Rotimi
Scientifica | Journal Article
Crossref
2020
Model Optimization and In Silico Analysis of Potential Dipeptidyl Peptidase IV Antagonists from GC-MS Identified Compounds in Nauclea latifolia Leaf Extracts
Franklyn Nonso Iheagwam, Olubanke Olujoke Ogunlana, Shalom Nwodo Chinedu
International Journal of Molecular Sciences | Journal Article
Crossref
2019
Potential Anti-Cancer Flavonoids Isolated From Caesalpinia bonduc Young Twigs and Leaves: Molecular Docking and In Silico Studies
Franklyn Nonso Iheagwam, Olubanke Olujoke Ogunlana, Oluseyi Ebenezer Ogunlana, Itunuoluwa Isewon, Jelili Oyelade
Bioinformatics and Biology Insights | Journal Article
Crossref
2019
GC-MS Analysis and Inhibitory Evaluation of Terminalia catappa Leaf Extracts on Major Enzymes Linked to Diabetes
Franklyn Nonso Iheagwam, Emmanuel Nsedu Israel, Kazeem Oyindamola Kayode, Opeyemi Christianah De Campos, Olubanke Olujoke Ogunlana, Shalom Nwodo Chinedu
Evidence-Based Complementary and Alternative Medicine | Journal Article
Crossref
2019
Data on in vivo antioxidant, hypolipidemic and hepatoprotective potential of Thaumatococcus daniellii (benn.) benth leaves.
Chinedu, S.N., F.N. Iheagwam, B.T. Makinde, B.O. Thorpe and O.C. Emiloju,
Data Brief, | Journal Article
Self Franklyn Nonso Iheagwam
2018
Comparative study on chemical composition and antioxidant activity of annona muricata plant parts cultivated in covenant university, Ota, Ogun state, Nigeria.
Elizabeth, O.O., I.F. Nonso, N.I. Adebola and O.J. John,
Curr. Res. Nutr. Food Sci. J., | Journal Article
Self Franklyn Nonso Iheagwam
2018
Phylogenetic relationship and genetic variation among Thaumatococcus daniellii and Megaphrynium macrostachyum ecotypes in Southwest Nigeria.
Chinedu, S.N., O.C. Emiloju, F.N. Iheagwam, S.O. Rotimi and J.O. Popoola,
Asian J. Plant Sci., | Journal Article
Self Franklyn Nonso Iheagwam
2018
Association between age, gender and body weight in educational institutions in Ota, southwest Nigeria.
Chinedu, S.N., O.C. Emiloju, D.E. Azuh, O.O. Ogunlana and F.N. Iheagwam,
Asian J. Epidemiol., | Journal Article
Self Franklyn Nonso Iheagwam
2017
Antioxidant and biochemical evaluation of Thaumatococcus daniellii seeds in rat.
Chinedu, S.N. F.N. Iheagwam, C.J. Anichebem, G.B. Ogunnaike and O.C. Emiloju,
J. Biol. Sci., | Journal Article
Self Franklyn Nonso Iheagwam
2017
Reactive sulphydryl groups in horse carbonmonoxyhaemoglobin.
Omotosho, O.E., F.N. Iheagwam, P.E. Imion, E.O. Idowu, P.C. Chinonyere and S.N. Chinedu,
Am. J. Biochem. Mol. Biol., | Journal Article
Self Franklyn Nonso Iheagwam
2017
Partial purification and kinetic properties of polygalacturonase from Solanum macrocarpum L. fruit.
Chinedu, S.N., O.P. Dayo-Odukoya and F.N. Iheagwam,
Biotechnology, | Journal Article
Self Franklyn Nonso Iheagwam
2017
Reactive sulphydryl groups present in horse (Equus ferus caballus) carbonmonoxyhaemoglobin by titrating with 5,5′-dithiobis-2-nitrobenzoate (DTNB).
Iheagwam, F.N., O.E. Omotosho, A. Oloruntola, A. Edobor-Osor, T.V. Omotosho and S.N. Chinedu,
FASEB J., | Journal Article
Self Franklyn Nonso Iheagwam
2016