About
Professional SummaryDr. Bashir Lawal obtained his PhD Degrees In Cancer Biology and Drug Discovery, from Taipei Medical University, Taiwan. His main area of research interest focuses on cancer genetics, immune biology, and Cancer Drug Discovery. He has published about 70 research articles in journals contributed as author/co-author.
Education
Academic Background-
Ph.D. Taipei Medical University, Taiwan Molecular Cancer Biology | Completed: 2022
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Ph.D. Taipei Medical University, Taiwan Cancer Cell Biology | Completed: 2022
Publications (84)
Selected Scholarly Contributions
Integrated Pharmacogenomic and Structure-Guided Analyses Link LCC-10 (NSC765599) to an MMP-Associated Extracellular Matrix Regulatory Network in Leukemia
2026
Investigating the Antidiabetic Effects of
Calotropis procera
: Preclinical Assessment
2026
Phenotype-Oriented Characterization of NSC828786 Identifies Convergent HPN-AMACR-Associated Transcriptomic Signatures in Prostate Adenocarcinoma and Broad-Spectrum Antiproliferative Activity
2026
Tumors hijack immune-privileging regulons via distinct cell types to confer T cell desertion and immunotherapy resistance across various cancers
2026
2026
Correction: Olugbodi et al. Silver Nanoparticles Stimulates Spermatogenesis Impairments and Hematological Alterations in Testis and Epididymis of Male Rats. Molecules 2020, 25, 1063
2025
Correction: Yeh et al. Identification of NSP3 (SH2D3C) as a Prognostic Biomarker of Tumor Progression and Immune Evasion for Lung Cancer and Evaluation of Organosulfur Compounds from Allium sativum L. as Therapeutic Candidates. Biomedicines 2021, 9, 1582
2025
Evaluation of terpenes rich Hura crepitans extract on glucose regulation and diabetic complications in STZ-induced diabetic rats
2024
In Vitro and In Silico Biological Studies of 4-Phenyl-2-quinolone (4-PQ) Derivatives as Anticancer Agents
2023
Identification of CDK1, PBK, and CHEK1 as an Oncogenic Signature in Glioblastoma: A Bioinformatics Approach to Repurpose Dapagliflozin as a Therapeutic Agent
2023
Rutin‐Rich Flavonoid Subfraction of Annona senegalensis Mitigates Trypanosoma brucei brucei Infection and Hematobiochemical Changes in Infected Mice
2023
A Systematic Review of Phytochemistry, Nutritional Composition, and Pharmacologic Application of Species of the Genus Viola in Noncommunicable Diseases (NCDs)
2023
RETRACTED: Attenuation of hyperglycemia-associated dyslipidemic, oxidative, cognitive, and inflammatory crises via modulation of neuronal ChEs/NF-κB/COX-2/NOx, and hepatorenal functional deficits by the Tridax procumbens extract
2023
Computational and Preclinical Prediction of the Antimicrobial Properties of an Agent Isolated from Monodora myristica: A Novel DNA Gyrase Inhibitor
2023
Apigetrin-enriched Pulmeria alba extract prevents assault of STZ on pancreatic β-cells and neuronal oxidative stress with concomitant attenuation of tissue damage and suppression of inflammation in the brain of diabetic rats
2023
Profiling the Antidiabetic Potential of Compounds Identified from Fractionated Extracts of Entada africana toward Glucokinase Stimulation: Computational Insight
2023
Combination Treatment of Omega‐3 Fatty Acids and Vitamin C Exhibited Promising Therapeutic Effect against Oxidative Impairment of the Liver in Methotrexate‐Intoxicated Mice
2022
Luteolin‐Rich Extract of Thespesia garckeana F. Hoffm. (Snot Apple) Contains Potential Drug‐Like Candidates and Modulates Glycemic and Oxidoinflammatory Aberrations in Experimental Animals
2022
2022
Identification of a Novel Theranostic Signature of Metabolic and Immune-Inflammatory Dysregulation in Myocardial Infarction, and the Potential Therapeutic Properties of Ovatodiolide, a Diterpenoid Derivative
2022
Identification of a novel immune-inflammatory signature of COVID-19 infections, and evaluation of pharmacokinetics and therapeutic potential of RXn-02, a novel small-molecule derivative of quinolone
2022
Transcriptomic discovery of a theranostic signature (SERPINE1/MMP3/COL1A1/SPP1) for head and neck squamous cell carcinomas and identification of antrocinol as a candidate drug
2022
Pharmacoinformatics and Preclinical Studies of NSC765690 and NSC765599, Potential STAT3/CDK2/4/6 Inhibitors with Antitumor Activities against NCI60 Human Tumor Cell Lines
2021
An Integrated Bioinformatics Study of a Novel Niclosamide Derivative, NSC765689, a Potential GSK3β/β-Catenin/STAT3/CD44 Suppressor with Anti-Glioblastoma Properties
2021
Network Pharmacological Analysis through a Bioinformatics Approach of Novel NSC765600 and NSC765691 Compounds as Potential Inhibitors of CCND1/CDK4/PLK1/CD44 in Cancer Types
2021
In-Silico Evaluation of Genetic Alterations in Ovarian Carcinoma and Therapeutic Efficacy of NSC777201, as a Novel Multi-Target Agent for TTK, NEK2, and CDK1
2021
A Preclinical Investigation of GBM-N019 as a Potential Inhibitor of Glioblastoma via Exosomal mTOR/CDK6/STAT3 Signaling
2021
Computational and Preclinical Evidence of Anti‐ischemic Properties of L‐Carnitine‐Rich Supplement via Stimulation of Anti‐inflammatory and Antioxidant Events in Testicular Torsed Rats
2021
Multi-Omics Data Analysis of Gene Expressions and Alterations, Cancer-Associated Fibroblast and Immune Infiltrations, Reveals the Onco-Immune Prognostic Relevance of STAT3/CDK2/4/6 in Human Malignancies
2021
Identification of Cancer Hub Gene Signatures Associated with Immune-Suppressive Tumor Microenvironment and Ovatodiolide as a Potential Cancer Immunotherapeutic Agent
2021
Pan-Cancer Analysis of Immune Complement Signature C3/C5/C3AR1/C5AR1 in Association with Tumor Immune Evasion and Therapy Resistance
2021
Multiomics Identification of Potential Targets for Alzheimer Disease and Antrocin as a Therapeutic Candidate
2021
Transcriptomic-Based Identification of the Immuno-Oncogenic Signature of Cholangiocarcinoma for HLC-018 Multi-Target Therapy Exploration
2021
Identification of NSP3 (SH2D3C) as a Prognostic Biomarker of Tumor Progression and Immune Evasion for Lung Cancer and Evaluation of Organosulfur Compounds from Allium sativum L. as Therapeutic Candidates
2021
Sterculia tragacantha Lindl leaf extract ameliorates STZ-induced diabetes, oxidative stress, inflammation and neuronal impairment.
2021
In vivo pharmacokinetic and anticancer studies of HH-N25, a selective inhibitor of topoisomerase I, and hormonal signaling for treating breast cancer.
2021
Phytochemical compositions, and hypoglycemic effect of methanol leaf extract of telfairia occidentalis in alloxan-induced diabetic rats.
2021
Alkaloidal fraction of diospyros mespiliformis protect against trypanosoma evansi-mediated haematological and hepatic impairment in infected rats.
2021
BC-N102 Suppress Breast Cancer Tumorigenesis by Interfering with Cell Cycle Regulatory Proteins and Hormonal Signaling, and Induction of Time-Course Arrest of Cell Cycle at G1/G0 Phase.
2021
In-silico investigation of curcumin drug-likeness, gene-targets and prognostic relevance of the targets in panels of human cancer cohorts.
2021
HNC0014, a Multi-Targeted Small-Molecule, Inhibits Head and Neck Squamous Cell Carcinoma by Suppressing c-Met/STAT3/CD44/PD-L1 Oncoimmune Signature and Eliciting Antitumor Immune Responses
2020
Antioxidant and hepatoprotective potentials of curcuminoid isolates from turmeric (
Curcuma longa
) rhizome on CCl
4
-induced hepatic damage in Wistar rats
2020
Characterization of anti-plasmodial, analgesic and anti-inflammatory fraction of Maytenus senegalensis (lam.) Exell leaf extract in mice
2020
Antiplasmodial effect and sub-acute toxicity of alkaloid, flavonoid and phenolic extracts of Sida acuta leaf on Plasmodium berghei-infected animals.
2020
Silver Nanoparticles Stimulates Spermatogenesis Impairments and Hematological Alterations in Testis and Epididymis of Male Rats.
2020
In vitro antioxidants, antimicrobials and biochemical response of methanol leaf extract of Eucalyptus camaldulensis following sub-acute administration to rats.
2019
Antioxidant and antimicrobial activities of naturally occurring flavonoids from M. heterophylla and the safety evaluation in wistar rats.
2019
Anti-plasmodial, anti-inflammatory, anti-nociceptive and safety profile of Maytenus senegalensis root bark extract on hepato-renal integrity in experimental animals.
2019
Antioxidant potential of Waltheria indica methanol leaf extract in Trypanosoma brucei brucei infected mice.
2019
Polyethylene glycol-modified nanocarrier encapsulation of Diminazene aceturate improved haematobio- chemical recovery in Trypanosoma brucei brucei infected rats.
2019
Human Genetic Markers and Structural Prediction ofPlasmodium falciparumMultidrug Resistance Gene(pfmdr1)for Ligand Binding in Pregnant Women Attending General Hospital Minna
2018
In-vitro antioxidants, antimicrobial and toxicological evaluation of Nigerian Zingiber officinale
2018
Diminazene aceturate modified nanocomposite for improved efficacy in acute trypanosome infection.
2018
Free radical scavenging, antimicrobial activities and effect of sub-acute exposure to Nigerian Xylopia aethiopica seed extract on liver and kidney functional indices of albino rat.
2018
African natural products with potential antioxidants and hepatoprotectives properties: a review
2017
Protective effects of crude and alkaloidal extracts of Tamarindus indica against acute inflammation and nociception in rats.
2017
Antimicrobial and free radical scavenging potentials of N-Hexane and ethyl acetate fractions of Phyllanthus fraternus.
2017
Effect of methanol extract of Musca domestica larva on some enzymes and haematological parameters in Trypanosoma brucei brucei-infected rats.
2017
Antioxidants and antimicrobial activities of methanol extract of Newbouldia laevis and Crateva adansonii.
2016
Antimicrobial evaluation, acute and sub-acute toxicity studies of Allium sativum.
2016
Comparative phytochemical and antinutritional constituents of Nigeria sweet and bitter honey varieties.
2016
Antioxidants and antimicrobial-activities of methanol leaf extract of Senna occidentalis.
2016
Drug leads agents from methanol extract of Nigerian bee (Apis mellifera) propolis.
2016
Phytochemical screening and GC-MS determination of bioactive constituents from methanol leaf extract of Senna occidentalis.
2015
Effect of methanol extract of Telfairia occcidentalis on haematological parameters in wister rats.
2015
Physicochemical properties and organoleptic quality of M. oleifera seed oil.
2015
Effect of different processing methods on nutritional composition of bitter leaf (Vernonia amygdalina).
2015
Antitrypanosomal activities of ethyl acetate extracts of honey bee (Apis Mellifera) and its effect on haematological parameters of Trypanosoma brucei brucei infected rats.
2015
Hepato-curative effects of methanol extract from Nigerian bee propolis in carbon tetrachloride (CCl4) intoxicated rats.
2015
Comparison of the nutritional value of egg yolk and egg albumin from domestic chicken, Guinea fowl and hybrid chicken.
2015
Evaluation of antioxidant activity of giant African snail (Archachatina maginata) haemolymph in CCl4-induced hepatotoxixity in albino rats.
2015
Potential antimalarials from African natural products: A review.
2015
GC-MS determination of bioactive constituents of giant African snail (Archachatina maginata) haemolymph.
2015
African natural products with potential anti-trypanosomal properties: A review.
2015
Phytochemicals and acute toxicity profile of aqueous and methanolic extracts of Crateva adansonii leaves in Swiss albino rats.
2015
Toxicological implications of methanol extract from Nigerian bee propolis on some selected rat tissues.
2015
Alteration in biochemical indices following chronic administration of methanolic extract of Nigeria bee propolis in Wistar rats.
2015
Biochemical evaluation in wister rats (Rattus novergicus) following chronic exposure of methanol leaf extract of Telfairia occcidentalis.
2015
Hematological status and organs/body-weight parameters in wister rats during chronic administration of Cassia occidentalis.
2015
Safety evaluation of giant African land snails (Archachatina maginata) haemolymph on hematological and biochemical parameters of albino rats.
2015
Haematopoetic effect of methanol extract of Nigerian honey bee (Apis mellifera) propolis in mice.
2015
Phytochemical composition and antimalarial activity of methanol leaf extract of Crateva adansonii in Plasmodium berghei infected mice.
2015
Effects of methanol extract of Musca domestica larvae on antioxidants enzymes in T. Brucei infected rats.
2014
Evaluation of phytochemicals, proximate, minerals and anti-nutritional compositions of yam peel, maize chaff and bean coat.
2014