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Ayman Moawad Mahmoud

Ayman Moawad Mahmoud

LiveDNA ID: 20.6186
177 Publications
0 Editorial Roles
0 Projects

Education

Academic Background
  • Ph.D. Beni-Suef University, Egypt Physiology | Completed: 2012

Publications (177)

Selected Scholarly Contributions
Modulation of Redox Homeostasis, Inflammation, and Necroptosis by Carbocisteine Protects Against Bisphenol A-Induced Male Reproductive Toxicity
Mohammed A. Alzoghaibi, Emad H. M. Hassanein, Mohammed F. Alotaibi, Abdullah M. Alzoghaibi, Hanan S. Althagafy, Hamada S. Qebesy, Amr M. T. Allam, Ayman M. Mahmoud
Bratislava Medical Journal | Journal Article
Crossref
2026
Protective role of S-carboxymethylcysteine against cyclophosphamide nephrotoxicity: involvement of Nrf2/HO-1 signaling and suppression of oxidative stress, inflammation, and apoptosis
Reem S. Alruhaimi, Emad H. M. Hassanein, Sulaiman M. Alnasser, Ahmad F. Ahmeda, Hanan S. Althagafy, Mostafa Sabry, Abdullatif A. Ahmed, Ayman M. Mahmoud
Molecular & Cellular Toxicology | Journal Article
Crossref
2026
Protective Effect of Arbutin Against Diabetic Nephropathy: Targeting Oxidative Stress, Inflammation, and Nrf2/HO-1 Pathway
Reem S. Alruhaimi, Sulaiman M. Alnasser, Ali F. Almutairy, Mohammed F. Alotaibi, Emad H. M. Hassanein, Ayman M. Mahmoud
Bratislava Medical Journal | Journal Article
Crossref
2026
Nifuroxazide attenuates bisphenol A–induced male reproductive toxicity by modulating oxidative stress, inflammation, and Nrf2/HO-1 and necroptosis pathways
Mohammed A. Alzoghaibi, Emad H.M. Hassanein, Mohammed F. Alotaibi, Abdullah M. Alzoghaibi, Hanan S. Althagafy, Hamada S. Qebesy, Amr M.T. Allam, Ayman M. Mahmoud
Tissue and Cell | Journal Article
Crossref
2026
Carbocisteine mitigates bisphenol A-mediated renal injury by modulating oxidative stress, Keap1/Nrf2/HO-1 pathway, endoplasmic reticulum stress, and inflammation
Reem S. Alruhaimi, Reem N. Alotaibi, Sulaiman M. Alnasser, Wafa S. Al-Thubiani, Nouf Aldawood, Emad H. M. Hassanein, Ayman M. Mahmoud
Toxicological Research | Journal Article
Crossref
2026
The angiotensin II receptor blocker candesartan mitigates cisplatin-induced myocardial injury via suppression of TLR-4/NF-κB/IRF-3/AP-1 signaling and restoration of antioxidant defenses
Emad H.M. Hassanein, Omnia A.M. Abd El-Ghafar, Sulaiman M. Alnasser, Reem S. Alruhaimi, Hanan S. Althagafy, Ahmed M. Atwa, Ayman M. Mahmoud
Tissue and Cell | Journal Article
Crossref
2026
Attenuation of NF-κB/NLRP3 inflammasome axis and oxidative stress, and upregulation of Nrf2/HO-1 signaling mediate the protective effect of S-carboxymethylcysteine against cyclophosphamide-induced cardiotoxicity
Reem S. Alruhaimi, Emad H.M. Hassanein, Sulaiman M. Alnasser, Ahmad F. Ahmeda, Hanan S. Althagafy, Amr M.T. Allam, Hamada S. Qebesy, Ayman M. Mahmoud
Tissue and Cell | Journal Article
Crossref
2025
Haloxylon salicornicum Phytochemicals Suppress NF‐κB, iNOS and Pro‐Inflammatory Cytokines in Lipopolysaccharide‐Induced Macrophages
Reem S. Alruhaimi, Omnia E Hussein, Sulaiman M. Alnasser, Ibrahim Elbagory, Mohammed A. Alzoghaibi, Emadeldin M. Kamel, Mohamed El Mohtadi, Ayman M. Mahmoud
Chemistry & Biodiversity | Journal Article
Crossref
2025
Unveiling the Molecular Mechanisms of Squalene Epoxidase Inhibition by Flavonoids from Erythrina speciosa: Integrative Computational and Experimental Insights
Rasha H. Elsayed, Ayman M. Mahmoud, Sayed A. El-Toumy, Sayed A. Ahmed, Bashir Salah, Al Mokhtar Lamsabhi, Emadeldin M. Kamel
Revista Brasileira de Farmacognosia | Journal Article
Crossref
2025
Computationally Guided Structural Modification of Centaureidin: A Novel Approach for Enhancing Antioxidant and Antitumor Activities for Drug Development
Reem S. Alruhaimi, Emadeldin M. Kamel, Sulaiman M. Alnasser, Ibrahim Elbagory, Ayman M. Mahmoud, Al Mokhtar Lamsabhi
Chemical Biology & Drug Design | Journal Article
Crossref
2025
Modulation of NF-κB/NLRP3 inflammasome axis, Nrf2/HO-1 signaling and attenuation of oxidative stress mediate the protective effect of ambroxol against cyclophosphamide cardiotoxicity
Reem S. Alruhaimi, Emad H.M. Hassanein, Sulaiman M. Alnasser, Ahmad F. Ahmeda, Hanan S. Althagafy, Amr M.T. Allam, Hamada S. Qebesy, Ayman M. Mahmoud
Biochemical and Biophysical Research Communications | Journal Article
Crossref
2025
Correction: Aladaileh et al. Formononetin Upregulates Nrf2/HO-1 Signaling and Prevents Oxidative Stress, Inflammation and Kidney Injury in Methotrexate-Induced Rats. Antioxidants 2019, 8, 430
Saleem H. Aladaileh, Omnia E. Hussein, Mohammad H. Abukhalil, Sultan A. M. Saghir, May Bin-Jumah, Manal A. Alfwuaires, Mousa O. Germoush, Amer A. Almaiman, Ayman M. Mahmoud
Antioxidants | Journal Article
Crossref
2025
3‐Hydroxy‐3‐Methylglutaryl Coenzyme‐A Inhibitory Activity of Padina pavonia Terpenoids: An Integrated In Vitro and In Silico Exploration
Reem S. Alruhaimi, Emadeldin M. Kamel, Sulaiman M. Alnasser, Al Mokhtar Lamsabhi, Ayman M. Mahmoud
Chemistry & Biodiversity | Journal Article
Crossref
2025
Androgen Receptor Blockade Induces the Phagocytosis of MRSA and Pseudomonas aeruginosa by Monocyte-Derived Macrophages In Vitro
Amina Belboul, Mohamed El Mohtadi, Abdulmannan Fadel, Jessica Mcloughlin, Ayman Mahmoud, Caitlin O’Malley, Jason Ashworth
Acta Microbiologica Hellenica | Journal Article
Crossref
2025
Correction: Ismaeil et al. Ameliorative Effect of Heat-Killed Lactobacillus plantarum L.137 and/or Aloe vera against Colitis in Mice. Processes 2020, 8, 225
Heba Ismaeil, Walied Abdo, Said Amer, Amin Tahoun, Diaa Massoud, Eatemad Zanaty, May Bin-Jumah, Ayman M. Mahmoud
Processes | Journal Article
Crossref
2024
Structural adaptations of the beak and oropharyngeal cavity roof in migratory Anas crecca: Distinctive scanning electron microscopic pattern of its filter feeding apparatus
Reem S. Alruhaimi, Mohamed M.A. Abumandour, Mohammed Kassab, Ahmed A. Elnegiry, Foad Farrag, Diaa Massoud, Ayman M. Mahmoud, Hazem Hamoda
Zoologischer Anzeiger | Journal Article
Crossref
2024
Cadmium-induced lung injury is associated with oxidative stress, apoptosis, and altered SIRT1 and Nrf2/HO-1 signaling; protective role of the melatonin agonist agomelatine
Reem S. Alruhaimi, Emad H. M. Hassanein, May N. Bin-Jumah, Ayman M. Mahmoud
Naunyn-Schmiedeberg's Archives of Pharmacology | Journal Article
Crossref
2024
Tongue microarchitecture and functional characterization of the lingual papillae in the desert hedgehog (Paraechinus aethiopicus)
Diaa Massoud, Mervat A. AbdRabou, Maged Fouda, Fayez Shaldoum, Barakat M. Alrashdi, Mousa O. Germoush, Haifa E. Alfassam, Aljohara M. Al‐ Otaibi, Soha A. Soliman, Hanan H. Abd‐Elhafeez, Mervat Hassan, Ayman M. Mahmoud
Journal of Experimental Zoology Part A: Ecological and Integrative Physiology | Journal Article
Crossref
2024
Mechanistic insights into carbonic anhydrase IX inhibition by coumarins from Calendula officinalis : in vitro and in silico approaches
Reem S. Alruhaimi, Emadeldin M. Kamel, Sulaiman M. Alnasser, Mohammed A. Alzoghaibi, Al Mokhtar Lamsabhi, Ayman M. Mahmoud
RSC Advances | Journal Article
Crossref
2024
Berberine attenuates inflammation and oxidative stress and modulates lymphocyte E‐NTPDase in acute hyperlipidemia
Reem S. Alruhaimi, Maisa Siddiq Abduh, Ahmad F. Ahmeda, Albandari Bin‐Ammar, Emadeldin M. Kamel, Emad H. M. Hassanein, Chen Li, Ayman M. Mahmoud
Drug Development Research | Journal Article
Crossref
2024
Farnesol prevents chlorpyrifos nephrotoxicity by modulating inflammatory mediators, Nrf2 and FXR and attenuating oxidative stress
Reem S. Alruhaimi, Mohammed F. Alotaibi, Sulaiman M. Alnasser, Mohammed A. Alzoghaibi, Mousa O. Germoush, Meshal Alotaibi, Emad H.M. Hassanein, Ayman M. Mahmoud
Food and Chemical Toxicology | Journal Article
Crossref
2024
Phytochemical Analysis and Anti‐dyslipidemia and Antioxidant Activities of Pluchea dioscoridis: In Vitro, In Silico and In Vivo Studies
Wageha S. Sultan, Ayman M. Mahmoud, Shimaa A. Ahmed, Reem S. Alruhaimi, Mohammed A. Alzoghaibi, Ashraf A. El‐Bassuony, Nabil A. Hasona, Emadeldin M. Kamel
Chemistry & Biodiversity | Journal Article
Crossref
2024
Oxidative Stress, Inflammation, and Altered Lymphocyte E-NTPDase Are Implicated in Acute Dyslipidemia in Rats: Protective Role of Arbutin
Reem S. Alruhaimi, Omnia E. Hussein, Sulaiman M. Alnasser, Mousa O. Germoush, Meshal Alotaibi, Emad H. M. Hassanein, Mohamed El Mohtadi, Ayman M. Mahmoud
Pharmaceuticals | Journal Article
Crossref
2024
Diallyl Disulfide Mitigates Cadmium Hepatotoxicity by Attenuating Oxidative Stress and TLR-4/NF-κB Signaling and Upregulating PPARγ
Reem S. Alruhaimi, Emad H.M. Hassanein, Mohammed F. Alotaibi, Mohammed A. Alzoghaibi, Omnia A.M. Abd El-Ghafar, Mostafa K. Mohammad, Sulaiman M. Alnasser, Ayman M. Mahmoud
Frontiers in Bioscience-Landmark | Journal Article
Crossref
2024
Integrating Computational Modeling and Experimental Validation to Unveil Tyrosinase Inhibition Mechanisms of Flavonoids from Alhagi graecorum
Reem S. Alruhaimi, Ayman M. Mahmoud, Sulaiman M. Alnasser, Mohammed F. Alotaibi, Ibrahim Elbagory, Ashraf A. El-Bassuony, Al Mokhtar Lamsabhi, Emadeldin M. Kamel
ACS Omega | Journal Article
Crossref
2024
The melatonin receptor agonist agomelatine protects against acute pancreatitis induced by cadmium by attenuating inflammation and oxidative stress and modulating Nrf2/HO-1 pathway
Reem S. Alruhaimi, Emad H.M. Hassanein, Mostafa K. Abd El-Aziz, Maisa Siddiq Abduh, Albandari Bin-Ammar, Emadeldin M. Kamel, Ayman M. Mahmoud
International Immunopharmacology | Journal Article
Crossref
2023
Impact of petroleum industry on goats in Saudi Arabia: heavy metal accumulation, oxidative stress, and tissue injury
Jamaan S. Ajarem, Ahmad K. Hegazy, Gamal A. Allam, Ahmed A. Allam, Saleh N. Maodaa, Ayman M. Mahmoud
Environmental Science and Pollution Research | Journal Article
Crossref
2023
Molecular modeling and DFT studies on the antioxidant activity of Centaurea scoparia flavonoids and molecular dynamics simulation of their interaction with β-lactoglobulin
Emadeldin M. Kamel, Albandari Bin-Ammar, Ashraf A. El-Bassuony, Mohammed M. Alanazi, Ali Altharawi, Ahmad F. Ahmeda, Ashwag S. Alanazi, Al Mokhtar Lamsabhi, Ayman M. Mahmoud
RSC Advances | Journal Article
Crossref
2023
Flavonoids of Haloxylon salicornicum (Rimth) prevent cisplatin-induced acute kidney injury by modulating oxidative stress, inflammation, Nrf2, and SIRT1
Shaymaa A. Ramadan, Emadeldin M. Kamel, Madeha A. Ewais, Akef A. Khowailed, Emad H. M. Hassanein, Ayman M. Mahmoud
Environmental Science and Pollution Research | Journal Article
Crossref
2023
Umbelliferone Inhibits Spermatogenic Defects and Testicular Injury in Lead-Intoxicated Rats by Suppressing Oxidative Stress and Inflammation, and Improving Nrf2/HO-1 Signaling [Retraction]
Mohammed F Alotaibi, Fakhria Al-Joufi, Howida S Abou Seif, Mohammed A Alzoghaibi, Laiche Djouhri, Ahmad F Ahmeda, Ayman M Mahmoud
Drug Design, Development and Therapy | Journal Article
Crossref
2023
The protective effect of 7-hydroxycoumarin against cisplatin-induced liver injury is mediated via attenuation of oxidative stress and inflammation and upregulation of Nrf2/HO-1 pathway
Demiana H. Sami, Ayman S. Soliman, Akef A. Khowailed, Reem S. Alruhaimi, Emad H. M. Hassanein, Emadeldin M. Kamel, Ayman M. Mahmoud
Environmental Science and Pollution Research | Journal Article
Crossref
2023
Cadmium cardiotoxicity is associated with oxidative stress and upregulated TLR-4/NF-kB pathway in rats; protective role of agomelatine
Reem S. Alruhaimi, Emad H.M. Hassanein, May N. Bin-Jumah, Ayman M. Mahmoud
Food and Chemical Toxicology | Journal Article
Crossref
2023
A Comparison of the Gene Expression Profiles of Non-Alcoholic Fatty Liver Disease between Animal Models of a High-Fat Diet and Methionine-Choline-Deficient Diet
Mohammed Abdullah Alshawsh, Abdulsamad Alsalahi, Salah Abdalrazak Alshehade, Sultan Ayesh Mohammed Saghir, Ahmad Faheem Ahmeda, Raghdaa Hamdan Al Zarzour, Ayman Moawad Mahmoud
Molecules | Journal Article
Crossref
2022
Melissa officinalis L. ameliorates oxidative stress and inflammation and upregulates Nrf2/HO-1 signaling in the hippocampus of pilocarpine-induced rats
Hagar N. Abd Allah, Manal Abdul-Hamid, Ayman M. Mahmoud, Eman S. Abdel-Reheim
Environmental Science and Pollution Research | Journal Article
Crossref
2022
Taxifolin Prevents Cisplatin Nephrotoxicity by Modulating Nrf2/HO-1 Pathway and Mitigating Oxidative Stress and Inflammation in Mice
Abdulkareem A. Alanezi, Afaf F. Almuqati, Manal A. Alfwuaires, Fawaz Alasmari, Nader I. Namazi, Osama Y. Althunibat, Ayman M. Mahmoud
Pharmaceuticals | Journal Article
Crossref
2022
Correction: Hassanein EHM, Ahmed MA, Sayed AM, Rashwan EK, Abd El‐Ghafar OAM, Mahmoud AM. Edaravone mitigates hemorrhagic cystitis by modulating Nrf2, TLR‐4/NF‐κB, and JAK1/STAT3 signaling in cyclophosphamide‐intoxicated rats. J Biochem Mol Toxicol. 2021 Nov;35(11):E22889
Emad H. M. Hassanein, Marwa A. Ahmed, Ahmed M. Sayed, Eman K. Rashwan, Omnia A. M. Abd El‐Ghafar, Ayman M. Mahmoud
Journal of Biochemical and Molecular Toxicology | Journal Article
Crossref
2022
Tramadol as an analgesic
Ayman M. Mahmoud, Emad H.M. Hassanein
Treatments, Mechanisms, and Adverse Reactions of Anesthetics and Analgesics | Book Chapter
Crossref
2022
Heavy Metal Accumulation, Tissue Injury, Oxidative Stress, and Inflammation in Dromedary Camels Living near Petroleum Industry Sites in Saudi Arabia
Jamaan S. Ajarem, Ahmad K. Hegazy, Gamal A. Allam, Ahmed A. Allam, Saleh N. Maodaa, Ayman M. Mahmoud
Animals | Journal Article
Crossref
2022
The Role of Flavonoids in Inhibiting IL-6 and Inflammatory Arthritis
Ayman M. Mahmoud, Ahmed M. Sayed, Osama S. Ahmed, Mohamed M. Abdel-Daim, Emad H.M. Hassanein
Current Topics in Medicinal Chemistry | Journal Article
Crossref
2022
Umbelliferone ameliorates oxidative stress and testicular injury, improves steroidogenesis and upregulates peroxisome proliferator-activated receptor gamma in type 2 diabetic rats
Mohamed A M Allam, Akef A Khowailed, Samah Elattar, Ayman M Mahmoud
Journal of Pharmacy and Pharmacology | Journal Article
Crossref
2022
Nano-Curcumin Prevents Copper Reproductive Toxicity by Attenuating Oxidative Stress and Inflammation and Improving Nrf2/HO-1 Signaling and Pituitary-Gonadal Axis in Male Rats
Wedad S. Sarawi, Ahlam M. Alhusaini, Laila M. Fadda, Hatun A. Alomar, Awatif B. Albaker, Hanan K. Alghibiwi, Amjad S. Aljrboa, Areej M. Alotaibi, Iman H. Hasan, Ayman M. Mahmoud
Toxics | Journal Article
Crossref
2022
The Effect of Dietary Saccharomyces cerevisiae on Growth Performance, Oxidative Status, and Immune Response of Sea Bream (Sparus aurata)
Ahmed F. Fath El-Bab, Sultan A. M. Saghir, Ibrahim Atta Abu El-Naser, Salwa M. M. Abo El-Kheir, Marwa F. Abdel-Kader, Reem S. Alruhaimi, Haifa A. Alqhtani, Ayman M. Mahmoud, Mohammed A. E. Naiel, Ali Ali El-Raghi
Life | Journal Article
Crossref
2022
Upregulation of Nrf2/HO-1 Signaling and Attenuation of Oxidative Stress, Inflammation, and Cell Death Mediate the Protective Effect of Apigenin against Cyclophosphamide Hepatotoxicity
Wesam Al-Amarat, Mohammad H. Abukhalil, Reem S. Alruhaimi, Haifa A. Alqhtani, Nouf Aldawood, Manal A. Alfwuaires, Osama Y. Althunibat, Saleem H. Aladaileh, Abdulmohsen I. Algefare, Abdulkareem A. Alanezi, Ali M. AbouEl-ezz, Ahmad F. Ahmeda, Ayman M. Mahmoud
Metabolites | Journal Article
Crossref
2022
Eco-friendly and biodegradable sodium alginate/quaternized chitosan hydrogel for controlled release of urea and its antimicrobial activity
Esraa G. Arafa, Magdy W. Sabaa, Riham R. Mohamed, Emadeldin M. Kamel, Ali M. Elzanaty, Ayman M. Mahmoud, Omayma F. Abdel-Gawad
Carbohydrate Polymers | Journal Article
Crossref
2022
Green Synthesis of Trimetallic Nanocomposite (Ru/Ag/Pd)-Np and Its In Vitro Antimicrobial and Anticancer Activities
Shaimaa Hussein, Ayman M. Mahmoud, Hassan A. Elgebaly, Omnia Magdy Hendawy, Emad H. M. Hassanein, Shaima M. N. Moustafa, Nasser F. Alotaibi, Amr M. Nassar
Journal of Chemistry | Journal Article
Crossref
2022
Femtosecond laser attenuates oxidative stress, inflammation, and liver fibrosis in rats: Possible role of PPARγ and Nrf2/HO-1 signaling
Aya E. Mohamed, Ayman M. Mahmoud, Wafaa R. Mohamed, Tarek Mohamed
Life Sciences | Journal Article
Crossref
2022
Candesartan Attenuates Cisplatin-Induced Lung Injury by Modulating Oxidative Stress, Inflammation, and TLR-4/NF-κB, JAK1/STAT3, and Nrf2/HO-1 Signaling
Ahmed M. Atwa, Omnia A. M. Abd El-Ghafar, Emad H. M. Hassanein, Somya E. Mahdi, Ghadir A. Sayed, Reem S. Alruhaimi, Haifa A. Alqhtani, Mohammed F. Alotaibi, Ayman M. Mahmoud
Pharmaceuticals | Journal Article
Crossref
2022
Azithromycin Mitigates Cisplatin-Induced Lung Oxidative Stress, Inflammation and Necroptosis by Upregulating SIRT1, PPARγ, and Nrf2/HO-1 Signaling
Emad H. M. Hassanein, Ghadir A. Sayed, Abdullah M. Alzoghaibi, Abdalmohsen S. Alammar, Basel A. Abdel-Wahab, Omnia A. M. Abd El-Ghafar, Somya E. Mahdi, Ahmed M. Atwa, Mohammed A. Alzoghaibi, Ayman M. Mahmoud
Pharmaceuticals | Journal Article
Crossref
2022
Galangin Attenuates Liver Injury, Oxidative Stress and Inflammation, and Upregulates Nrf2/HO-1 Signaling in Streptozotocin-Induced Diabetic Rats
Wesam Al-Amarat, Mohammad H. Abukhalil, Osama Y. Althunibat, Manal A. Alfwuaires, Mashael M. Alnamshan, Amany I. Alqosaibi, Ahmad F. Ahmeda, Emadeldin M. Kamel, Hany H. Arab, Ayman M. Mahmoud
Processes | Journal Article
Crossref
2021
Nano-Curcumin Prevents Cardiac Injury, Oxidative Stress and Inflammation, and Modulates TLR4/NF-κB and MAPK Signaling in Copper Sulfate-Intoxicated Rats
Wedad S. Sarawi, Ahlam M. Alhusaini, Laila M. Fadda, Hatun A. Alomar, Awatif B. Albaker, Amjad S. Aljrboa, Areej M. Alotaibi, Iman H. Hasan, Ayman M. Mahmoud
Antioxidants | Journal Article
Crossref
2021
Mesenchymal stem cells ameliorate oxidative stress, inflammation, and hepatic fibrosis via Nrf2/HO-1 signaling pathway in rats
Sally M. Khadrawy, Hanaa M. Mohamed, Ayman M. Mahmoud
Environmental Science and Pollution Research | Journal Article
Crossref
2021
The modulatory role of sulfated and non-sulfated small molecule heparan sulfate-glycomimetics in endothelial dysfunction: absolute structural clarification, molecular docking and simulated dynamics, SAR analyses and ADMET studies
Daniel M. Gill, Ana Paula R. Povinelli, Gabriel Zazeri, Sabrina A. Shamir, Ayman M. Mahmoud, Fiona L. Wilkinson, M. Yvonne Alexander, Marinonio L. Cornelio, Alan M. Jones
RSC Medicinal Chemistry | Journal Article
Crossref
2021
The Interplay of Oxidative Stress and Inflammation: Mechanistic Insights and Therapeutic Potential of Antioxidants
Ayman M. Mahmoud, Fiona L. Wilkinson, Mansur A. Sandhu, Adam P. Lightfoot
Oxidative Medicine and Cellular Longevity | Journal Article
Crossref
2021
Ameliorative Effect of Thymoquinone‐Loaded PLGA Nanoparticles on Chronic Lung Injury Induced by Repetitive Intratracheal Instillation of Lipopolysaccharide in Rats
Sultan A. M. Saghir, Naif A. Al-Gabri, Abdelmoniem A. Ali, Al-Sayed R. Al-Attar, Mosa’d Al-Sobarry, Omar Y. A. Al-shargi, Amal Alotaibi, Mohammed Al-zharani, Fahd A. Nasr, Nader Al-Balagi, Mahfoudh A. M. Abdulghani, Sulaiman M. Alnaimat, Osama Y. Althunibat, Ayman M. Mahmoud
Oxidative Medicine and Cellular Longevity | Journal Article
Crossref
2021
The Role of Natural and Synthetic Antioxidants in Modulating Oxidative Stress in Drug‐Induced Injury and Metabolic Disorders 2020
Ayman M. Mahmoud, Fiona L. Wilkinson, Adam P. Lightfoot, Julia M. Dos Santos, Mansur A. Sandhu
Oxidative Medicine and Cellular Longevity | Journal Article
Crossref
2021
Acetovanillone prevents cyclophosphamide‐induced acute lung injury by modulating PI3K/Akt/mTOR and Nrf2 signaling in rats
Omnia A.M. Abd El‐Ghafar, Emad H.M. Hassanein, Ahmed M. Sayed, Eman K. Rashwan, Abdel‐Gawad S. Shalkami, Ayman M. Mahmoud
Phytotherapy Research | Journal Article
Crossref
2021
Anethum graveolens Prevents Liver and Kidney Injury, Oxidative Stress and Inflammation in Mice Exposed to Nicotine Perinatally
Jamaan Ajarem, Saleh Maodaa, Hamed El-Serehy, Naif Altoom, Ahmed Allam, Rene Hernandez-Bautista, Ayman Mahmoud
Coatings | Journal Article
Crossref
2021
Edaravone mitigates hemorrhagic cystitis by modulating Nrf2, TLR‐4/NF‐κB, and JAK1/STAT3 signaling in cyclophosphamide‐intoxicated rats
Emad H. M. Hassanein, Marwa A. Ahmed, Ahmed M. Sayed, Eman K. Rashwan, Omnia A. M. Abd El‐Ghafar, Ayman M. Mahmoud
Journal of Biochemical and Molecular Toxicology | Journal Article
Crossref
2021
Visnagin prevents isoproterenol‐induced myocardial injury by attenuating oxidative stress and inflammation and upregulating Nrf2 signaling in rats
Mohammad H. Abukhalil, Omnia E. Hussein, Saleem H. Aladaileh, Osama Y. Althunibat, Wesam Al‐Amarat, Sultan A. Saghir, Manal A. Alfwuaires, Abdulmohsen I. Algefare, Khalid M. Alanazi, Farhan K. Al‐Swailmi, Emadeldin M. Kamel, Ayman M. Mahmoud
Journal of Biochemical and Molecular Toxicology | Journal Article
Crossref
2021
Curcumin and Nano-Curcumin Mitigate Copper Neurotoxicity by Modulating Oxidative Stress, Inflammation, and Akt/GSK-3β Signaling
Wedad S. Sarawi, Ahlam M. Alhusaini, Laila M. Fadda, Hatun A. Alomar, Awatif B. Albaker, Amjad S. Aljrboa, Areej M. Alotaibi, Iman H. Hasan, Ayman M. Mahmoud
Molecules | Journal Article
Crossref
2021
Effect of visnagin on altered steroidogenesis and spermatogenesis, and testicular injury induced by the heavy metal lead.
Ajarem, J.S., A.K. Hegazy, G.A. Allam, A.A. Allam, S.N. Maodaa and A.M. Mahmoud,
Comb. Chem. High Throughput Screening, | Journal Article
Self Ayman Moawad Mahmoud
2021
Acute inflammation and oxidative stress induced by lipopolysaccharide and the ameliorative effect of stingless bee honey.
Ranneh, Y., A.M. Mahmoud, A. Fadel, M. Albujja, A.M. Akim, H.A. Hamid and H. Khazaai,
Comb. Chem. High Throughput Screening, | Journal Article
Self Ayman Moawad Mahmoud
2021
Ferulic acid prevents oxidative stress, inflammation, and liver injury via upregulation of Nrf2/HO-1 signaling in methotrexate-induced rats
Ayman M. Mahmoud, Omnia E. Hussein, Walaa G. Hozayen, May Bin-Jumah, Sanaa M. Abd El-Twab
Environmental Science and Pollution Research | Journal Article
Crossref
2020
Ameliorative Effect of Heat-Killed Lactobacillus plantarum L.137 and/or Aloe vera against Colitis in Mice
Heba Ismaeil, Walied Abdo, Said Amer, Amin Tahoun, Diaa Massoud, Eatemad Zanaty, May Bin-Jumah, Ayman M. Mahmoud
Processes | Journal Article
Crossref
2020
Liposomal Resveratrol and/or Carvedilol Attenuate Doxorubicin-Induced Cardiotoxicity by Modulating Inflammation, Oxidative Stress and S100A1 in Rats
Abeer M. Alanazi, Laila Fadda, Ahlam Alhusaini, Rehab Ahmad, Iman H. Hasan, Ayman M. Mahmoud
Antioxidants | Journal Article
Crossref
2020
Curcumin and Selenium Prevent Lipopolysaccharide/Diclofenac-Induced Liver Injury by Suppressing Inflammation and Oxidative Stress
Manal H. Al-dossari, Laila M. Fadda, Hala A. Attia, Iman H. Hasan, Ayman M. Mahmoud
Biological Trace Element Research | Journal Article
Crossref
2020
Perinatal Exposure to Tartrazine Triggers Oxidative Stress and Neurobehavioral Alterations in Mice Offspring
Gadah Albasher, Najla Maashi, Saleh Alfarraj, Rafa Almeer, Tarfa Albrahim, Fatimah Alotibi, May Bin-Jumah, Ayman M. Mahmoud
Antioxidants | Journal Article
Crossref
2020
Curcumin Prevents Cyclophosphamide-Induced Lung Injury in Rats by Suppressing Oxidative Stress and Apoptosis
Sultan A. M. Saghir, Sulaiman A. Alharbi, Maged A. Al-Garadi, Naif Al-Gabri, Hagar Y. Rady, Nouran K. Olama, Mahfoudh A. M. Abdulghani, Amir M. Al Hroob, Amer A. Almaiman, May Bin-Jumah, Ayman M. Mahmoud, Medhat Taha
Processes | Journal Article
Crossref
2020
Metabolomic Profiling and Antioxidant, Anticancer and Antimicrobial Activities of Hyphaene thebaica
Ghada A. Taha, Ibrahim B. Abdel-Farid, Hassan A. Elgebaly, Usama A. Mahalel, Mohamed G. Sheded, May Bin-Jumah, Ayman M. Mahmoud
Processes | Journal Article
Crossref
2020
Inflammasome Activation in Bovine Peripheral Blood-Derived Macrophages Is Associated with Actin Rearrangement
Amin Tahoun, Kirsty Jensen, Hanem El-Sharkawy, David Gally, Amira M. Rizk, Jamaan Ajarem, Ahmed Allam, Ayman M. Mahmoud
Animals | Journal Article
Crossref
2020
Coumarins as Modulators of the Keap1/Nrf2/ARE Signaling Pathway
Emad H. M. Hassanein, Ahmed M. Sayed, Omnia E. Hussein, Ayman M. Mahmoud
Oxidative Medicine and Cellular Longevity | Journal Article
Crossref
2020
Farnesol attenuates oxidative stress and liver injury and modulates fatty acid synthase and acetyl-CoA carboxylase in high cholesterol-fed rats
Mohammad H. Abukhalil, Omnia E. Hussein, May Bin-Jumah, Sultan A. M. Saghir, Mousa O. Germoush, Hassan A. Elgebaly, Nermeen M. Mosa, Ismail Hamad, Moath M. Qarmush, Emad M. Hassanein, Emadeldin M. Kamel, Rene Hernandez-Bautista, Ayman M. Mahmoud
Environmental Science and Pollution Research | Journal Article
Crossref
2020
Evaluation of Bifidobacteria and Lactobacillus Probiotics as Alternative Therapy for Salmonella typhimurium Infection in Broiler Chickens
Hanem El-Sharkawy, Amin Tahoun, Amira M. Rizk, Tohru Suzuki, Walid Elmonir, Eldsokey Nassef, Mustafa Shukry, Mousa O. Germoush, Foad Farrag, May Bin-Jumah, Ayman M. Mahmoud
Animals | Journal Article
Crossref
2020
Umbelliferone Inhibits Spermatogenic Defects and Testicular Injury in Lead-Intoxicated Rats by Suppressing Oxidative Stress and Inflammation, and Improving Nrf2/HO-1 Signaling
Mohammed F Alotaibi, Fakhria Al-Joufi, Howida S Abou Seif, Mohammed A Alzoghaibi, Laiche Djouhri, Ahmad F Ahmeda, Ayman M Mahmoud
Drug Design, Development and Therapy | Journal Article
Crossref
2020
Edaravone and Acetovanillone Upregulate Nrf2 and PI3K/Akt/mTOR Signaling and Prevent Cyclophosphamide Cardiotoxicity in Rats
Emad HM Hassanein, Omnia AM Abd El-Ghafar, Marwa A Ahmed, Ahmed M Sayed, Wail M Gad-Elrab, Jamaan S Ajarem, Ahmed A Allam, Ayman M Mahmoud
Drug Design, Development and Therapy | Journal Article
Crossref
2020
Prevalence and Association of Transfusion Transmitted Infections with ABO and Rh Blood Groups among Blood Donors at the National Blood Bank, Amman, Jordan
Amir M. Al Hroob, Sultan A. M. Saghir, Amer A. Almaiman, Omar S. A. Alsalahi, Abdullah S. Al-Wajeeh, Omar Y. A. Al-Shargi, Nader Al-Balagi, Ayman M. Mahmoud
Medicina | Journal Article
Crossref
2020
Arctium lappa Root Extract Prevents Lead-Induced Liver Injury by Attenuating Oxidative Stress and Inflammation, and Activating Akt/GSK-3β Signaling
Ahlam Alhusaini, Laila Fadda, Iman H. Hasan, Hanaa M. Ali, Naglaa F. El Orabi, Amira M. Badr, Enas Zakaria, Abeer M. Alenazi, Ayman M. Mahmoud
Antioxidants | Journal Article
Crossref
2019
Ferulic acid protects against methotrexate nephrotoxicityviaactivation of Nrf2/ARE/HO-1 signaling and PPARγ, and suppression of NF-κB/NLRP3 inflammasome axis
Ayman M. Mahmoud, Omnia E. Hussein, Sanaa M. Abd El-Twab, Walaa G. Hozayen
Food & Function | Journal Article
Crossref
2019
Umbelliferone Ameliorates CCl4-Induced Liver Fibrosis in Rats by Upregulating PPARγ and Attenuating Oxidative Stress, Inflammation, and TGF-β1/Smad3 Signaling
Ayman M. Mahmoud, Walaa G. Hozayen, Iman H. Hasan, Eman Shaban, May Bin-Jumah
Inflammation | Journal Article
Crossref
2019
Beneficial Effects of Citrus Flavonoids on Cardiovascular and Metabolic Health
Ayman M. Mahmoud, Rene J. Hernández Bautista, Mansur A. Sandhu, Omnia E. Hussein
Oxidative Medicine and Cellular Longevity | Journal Article
Crossref
2019
Chronic exposure to 35% carbamide peroxide tooth bleaching agent induces histological and hematological alterations, oxidative stress, and inflammation in mice
Gadah Al-Basher, Hind Al-Motiri, Saleh Al-Farraj, Fatimah Al-Otibi, Nouf Al-Sultan, Noorah Al-Kubaisi, Dalia Al-Sarar, Monerah Al-Dosary, May Bin-Jumah, Ayman M. Mahmoud
Environmental Science and Pollution Research | Journal Article
Crossref
2019
Chicoric acid prevents methotrexate-induced kidney injury by suppressing NF-κB/NLRP3 inflammasome activation and up-regulating Nrf2/ARE/HO-1 signaling
Sanaa M. Abd El-Twab, Omnia E. Hussein, Walaa G. Hozayen, May Bin-Jumah, Ayman M. Mahmoud
Inflammation Research | Journal Article
Crossref
2019
Modulating Oxidative Stress in Drug-Induced Injury and Metabolic Disorders: The Role of Natural and Synthetic Antioxidants
Ayman M. Mahmoud, Fiona L. Wilkinson, Mansur A. Sandhu, Julia M. Dos Santos, M. Yvonne Alexander
Oxidative Medicine and Cellular Longevity | Journal Article
Crossref
2019
Ameliorative Effect of Beta vulgaris Root Extract on Chlorpyrifos-Induced Oxidative Stress, Inflammation and Liver Injury in Rats
Gadah Albasher, Rafa Almeer, Fatimah O. Al-Otibi, Noorah Al-Kubaisi, Ayman M. Mahmoud
Biomolecules | Journal Article
Crossref
2019
Galangin Activates Nrf2 Signaling and Attenuates Oxidative Damage, Inflammation, and Apoptosis in a Rat Model of Cyclophosphamide-Induced Hepatotoxicity
Saleem H. Aladaileh, Mohammad H. Abukhalil, Sultan A. M. Saghir, Hamza Hanieh, Manal A. Alfwuaires, Amer A. Almaiman, May Bin-Jumah, Ayman M. Mahmoud
Biomolecules | Journal Article
Crossref
2019
Effects of Mining Activities on Gerbillus nanus in Saudi Arabia: A Biochemical and Histological Study
Ahmed M. Almalki, Jamaan Ajarem, Naif Altoom, Fahed S. Al-Otaibi, Saleh N. Maodaa, Ahmed A. Allam, Ayman M. Mahmoud
Animals | Journal Article
Crossref
2019
Antihyperlipidemic and Antioxidant Effects of Averrhoa Carambola Extract in High-Fat Diet-Fed Rats
Saleem Aladaileh, Sultan Saghir, Kisantini Murugesu, Amirin Sadikun, Ashfaq Ahmad, Gurjeet Kaur, Ayman Mahmoud, Vikneswaran Murugaiyah
Biomedicines | Journal Article
Crossref
2019
Mesoporous Silica Nanoparticles Trigger Liver and Kidney Injury and Fibrosis Via Altering TLR4/NF-κB, JAK2/STAT3 and Nrf2/HO-1 Signaling in Rats
Ayman M. Mahmoud, Ekram M. Desouky, Walaa G. Hozayen, May Bin-Jumah, El-Shaymaa El-Nahass, Hanan A. Soliman, Ahmed A. Farghali
Biomolecules | Journal Article
Crossref
2019
Formononetin Upregulates Nrf2/HO-1 Signaling and Prevents Oxidative Stress, Inflammation, and Kidney Injury in Methotrexate-Induced Rats
Saleem H. Aladaileh, Omnia E. Hussein, Mohammad H. Abukhalil, Sultan A. M. Saghir, May Bin-Jumah, Manal A. Alfwuaires, Mousa O. Germoush, Amer A. Almaiman, Ayman M. Mahmoud
Antioxidants | Journal Article
Crossref
2019
Curcumin Ameliorates Lead-Induced Hepatotoxicity by Suppressing Oxidative Stress and Inflammation, and Modulating Akt/GSK-3β Signaling Pathway
Ahlam Alhusaini, Laila Fadda, Iman H. Hasan, Enas Zakaria, Abeer M. Alenazi, Ayman M. Mahmoud
Biomolecules | Journal Article
Crossref
2019
Use of Spilopelia senegalensis as a Biomonitor of Heavy Metal Contamination from Mining Activities in Riyadh (Saudi Arabia)
Ahmed M. Almalki, Jamaan Ajarem, Ahmed A. Allam, Hamed A. El-Serehy, Saleh N. Maodaa, Ayman M. Mahmoud
Animals | Journal Article
Crossref
2019
Consumption of Terpenoids-Rich Padina pavonia Extract Attenuates Hyperglycemia, Insulin Resistance and Oxidative Stress, and Upregulates PPARγ in a Rat Model of Type 2 Diabetes
Mousa O. Germoush, Hassan A. Elgebaly, Sherif Hassan, Emadeldin M. Kamel, May Bin-Jumah, Ayman M. Mahmoud
Antioxidants | Journal Article
Crossref
2019
Olea europaea leaf extract up-regulates Nrf2/ARE/HO-1 signaling and attenuates cyclophosphamide-induced oxidative stress, inflammation and apoptosis in rat kidney.
AlHaithloul, H.A.S., M.F. Alotaibi, M. Bin-Jumah, H. Elgebaly and A.M. Mahmoud,
Biomed. Pharmacother., | Journal Article
Self Ayman Moawad Mahmoud
2019
Pathophysiological mechanisms of diabetic cardiomyopathy and the therapeutic potential of epigallocatechin-3-gallate.
Al Hroob, A.M., M.H. Abukhalil, O.E. Hussein and A.M. Mahmoud,
Biomed. Pharmacother., | Journal Article
Self Ayman Moawad Mahmoud
2019
Deleterious effects of perinatal exposure to potassium bromate on the development of offspring of Swiss mice.
Allam, A.A., S.I. Othman and A.M. Mahmoud,
Toxicol. Ind. Health, | Journal Article
Self Ayman Moawad Mahmoud
2019
Chronic exposure to the opioid tramadol induces oxidative damage, inflammation and apoptosis and alters cerebral monoamine neurotransmitters in rats.
Mohamed, H.M. and A.M. Mahmoud,
Biomed. Pharmacother., | Journal Article
Self Ayman Moawad Mahmoud
2019
Obesity: Pathophysiology, monosodium glutamate-induced model and anti-obesity medicinal plants.
Bautista, R.J.H., A.M. Mahmoud, M. Konigsberg and N.E.L.D. Guerrero,
Biomed. Pharmacother., | Journal Article
Self Ayman Moawad Mahmoud
2019
Cardiac and pulmonary toxicity of mesoporous silica nanoparticles is associated with excessive ROS production and redox imbalance in Wistar rats.
Hozayen, W.G., A.M. Mahmoud, E.M. Desouky, E.S. El-Nahass, H.A. Soliman and A.A. Farghali,
Biomed. Pharmacother., | Journal Article
Self Ayman Moawad Mahmoud
2019
Fisetin ameliorates oxidative stress, inflammation and apoptosis in diabetic cardiomyopathy.
Althunibat, O.Y., A.M. Al Hroob, M.H. Abukhalil, M.O. Germoush, M. Bin-Jumah and A.M. Mahmoud,
Life Sci., | Journal Article
Self Ayman Moawad Mahmoud
2019
Bee venom and hesperidin effectively mitigate complete Freund’s adjuvant-induced arthritis via immunomodulation and enhancement of antioxidant defense system.
Ahmed, O., H. Fahim, A. Mahmoud and E. Ahmed,
Arch. Rheumatol., | Journal Article
Self Ayman Moawad Mahmoud
2018
Perinatal exposure to energy drink induces oxidative damage in the liver, kidney and brain and behavioral alterations in mice offspring.
Al-Basher, G.I., H. Aljabal, R.S. Almeer, A.A. Allam and A.M. Mahmoud,
Biomed. Pharmacother., | Journal Article
Self Ayman Moawad Mahmoud
2018
The effect of extrusion screw-speed on the water extractability and molecular weight distribution of arabinoxylans from defatted rice bran.
Fadel, A., A. Plunkett, J. Ashworth, A.M. Mahmoud, Y. Ranneh, M. El Mohtadi and W. Li,
J. Food Sci. Technol., | Journal Article
Self Ayman Moawad Mahmoud
2018
Olive oil and leaf extract prevent fluoxetine-induced hepatotoxicity by attenuating oxidative stress, inflammation and apoptosis.
Elgebaly, H.A., N.M. Mosa, M. Allach, K.F. El-Massry, A.H. El-Ghorab, A.M. Al Hroob and A.M. Mahmoud,
Biomed. Pharmacother., | Journal Article
Self Ayman Moawad Mahmoud
2018
Simvastatin ameliorates diabetic nephropathy by attenuating oxidative stress and apoptosis in a rat model of streptozotocin-induced type 1 diabetes.
Al-Rasheed, N.M., N.M. Al-Rasheed, Y.A. Bassiouni, I.H. Hasan, M.A. Al-Amin, H.N. Al-Ajmi and A.M. Mahmoud,
Biomed. Pharmacother., | Journal Article
Self Ayman Moawad Mahmoud
2018
Stone quarrying induces organ dysfunction and oxidative stress in Meriones libycus.
Al-Otaibi, F.S., J.S. Ajarem, M.A. Abdel-Maksoud, S. Maodaa, A.A. Allam, G.I. Al-Basher and A.M. Mahmoud,
Toxicol. Ind. Health, | Journal Article
Self Ayman Moawad Mahmoud
2018
Improving the extractability of arabinoxylans and the molecular weight of wheat endosperm using extrusion processing.
Fadel, A., J. Ashworth, A. Plunkett, A.M. Mahmoud, Y. Ranneh and W. Li,
J. Cereal Sci., | Journal Article
Self Ayman Moawad Mahmoud
2018
Ginger alleviates hyperglycemia-induced oxidative stress, inflammation and apoptosis and protects rats against diabetic nephropathy.
Al Hroob, A.M., M.H. Abukhalil, R.D. Alghonmeen and A.M. Mahmoud,
Biomed. Pharmacother., | Journal Article
Self Ayman Moawad Mahmoud
2018
Health-related effects and improving extractability of cereal arabinoxylans.
Fadel, A., A.M. Mahmoud, J.J. Ashworth, W. Li, Y.L. Ng and A. Plunkett,
Int. J. Biol. Macromol., | Journal Article
Self Ayman Moawad Mahmoud
2018
Commiphora molmol protects against methotrexate-induced nephrotoxicity by up-regulating Nrf2/ARE/HO-1 signaling.
Mahmoud, A.M., M.O. Germoush, K.M. Al-Anazi, A.H. Mahmoud, M.A. Farah and A.A. Allam,
Biomed. Pharmacother., | Journal Article
Self Ayman Moawad Mahmoud
2018
Umbelliferone prevents oxidative stress, inflammation and hematological alterations and modulates glutamate-nitric oxide-cGMP signaling in hyperammonemic rats.
Germoush, M.O., S.I. Othman, M.A. Al-Qaraawi, H.M. Al-Harbi and O.E. Hussein et al.,
Biomed. Pharmacother., | Journal Article
Self Ayman Moawad Mahmoud
2018
Glucagon decreases IGF-1 bioactivity in humans, independently of insulin, by modulating its binding proteins.
Sarem, Z., C. Bumke-Vogt, A.M. Mahmoud, B. Assefa and M.O. Weickert et al.,
J. Clin. Endocrinol. Metab., | Journal Article
Self Ayman Moawad Mahmoud
2017
Fingerprinting of strong spermatogenesis steroidal saponins in male flowers of Phoenix dactylifera (date palm) by LC-ESI-MS.
Hamed, A.I., R.B. Said, A.S. Al-Ayed, J. Moldoch and U.A. Mahalel et al.,
Nat. Prod. Res., | Journal Article
Self Ayman Moawad Mahmoud
2017
Modulatory effect of berberine on adipose tissue PPARγ, adipocytokines and oxidative stress in high fat diet/streptozotocin-induced diabetic rats.
Mahmoud, A.M., M.M. Abdel-Rahman, N.A. Bastawy and H.M. Eissa,
J. Applied Pharmaceut. Sci., | Journal Article
Self Ayman Moawad Mahmoud
2017
Berberine mitigates methotrexate-induced oxidative stress and inflammation in the cerebrum of rats.
Hozayen, W.G., S.M. Ramadan, A. Fadel and A.M. Mahmoud,
J. Applied Pharmaceut. Sci., | Journal Article
Self Ayman Moawad Mahmoud
2017
Hesperidin protects against diethylnitrosamine/carbon tetrachloride-induced renal repercussions via up-regulation of Nrf2/HO-1 signaling and attenuation of oxidative stress.
Aly, M.S., S.R. Galaly, N. Moustafa, H.M. Mohammed, S.M. Khadrawy and A.M. Mahmoud,
J. Applied Pharmaceut. Sci., | Journal Article
Self Ayman Moawad Mahmoud
2017
Hesperidin protects against chemically induced hepatocarcinogenesis via modulation of Nrf2/ARE/HO-1, PPARγ and TGF-β1/Smad3 signaling and amelioration of oxidative stress and inflammation.
Mahmoud, A.M., H.M. Mohammed, S.M. Khadrawy and S.R. Galaly,
Chemico-Biol. Interact., | Journal Article
Self Ayman Moawad Mahmoud
2017
Exercise amaliorates metabolic disturbances and oxidative stress in diabetic cardiomyopathy: Possible underlying mechanisms.
Mahmoud, A.M.,
Adv. Exp. Med. Biol., | Journal Article
Self Ayman Moawad Mahmoud
2017
Commiphora molmol resin attenuates diethylnitrosamine/phenobarbital-induced hepatocarcinogenesis by modulating oxidative stress, inflammation, angiogenesis and Nrf2/ARE/HO-1 signaling.
Mahmoud, A.M., A.R. Zaki, M.E. Hassan and G. Mostafa-Hedeab,
Chemico-Biol. Interact., | Journal Article
Self Ayman Moawad Mahmoud
2017
Berberine ameliorates methotrexate-induced liver injury by activating Nrf2/HO-1 pathway and PPARγ and suppressing oxidative stress and apoptosis in rats.
Mahmoud, A.M., W.G. Hozayen and S.M. Ramadan,
Biomed. Pharmacother., | Journal Article
Self Ayman Moawad Mahmoud
2017
Caffeic acid phenethyl ester protects the brain against hexavalent chromium toxicity by enhancing endogenous antioxidants and modulating the JAK/STAT signaling pathway.
Mahmoud, A.M. and S.M. Abd El-Twab,
Biomed. Pharmacother., | Journal Article
Self Ayman Moawad Mahmoud
2017
Methotrexate hepatotoxicity is associated with oxidative stress, and down-regulation of PPARγ and Nrf2: Protective effect of 18β-glycyrrhetinic acid.
Mahmoud, A.M., O.E. Hussein, W.G. Hozayen and S.M. Abd El-Twab,
Chemico-Biol. Interact., | Journal Article
Self Ayman Moawad Mahmoud
2017
Consumption of polyphenol-rich Morus alba leaves extract attenuates early diabetic retinopathy: The underlying mechanism.
Mahmoud, A.M., S.M. Abd El-Twab and E.S. Abdel-Reheim,
Eur. J. Nutr., | Journal Article
Self Ayman Moawad Mahmoud
2017
Endothelial microparticles prevent lipid-induced endothelial damage via Akt/eNOS signaling and reduced oxidative stress.
Mahmoud, A.M., F.L. Wilkinson, E.M. McCarthy, D. Moreno-Martinez and A. Langford-Smith et al.,
FASEB J., | Journal Article
Self Ayman Moawad Mahmoud
2017
A novel role for small molecule glycomimetics in the protection against lipid-induced endothelial dysfunction: Involvement of Akt/eNOS and Nrf2/ARE signaling.
Mahmoud, A.M., F.L. Wilkinson, A.M. Jones, J.A. Wilkinson, M. Romero, J. Duarte and M.Y. Alexander,
Biochim. Biophys. Acta (BBA)-Gen. Subj., | Journal Article
Self Ayman Moawad Mahmoud
2017
Possible involvement of Nrf2 and PPARγ up-regulation in the protective effect of umbelliferone against cyclophosphamide-induced hepatotoxicity.
Mahmoud, A.M., M.O. Germoush, M.F. Alotaibi and O.E. Hussein,
Biomed. Pharmacother., | Journal Article
Self Ayman Moawad Mahmoud
2017
Green tea protects against perinatal nicotine-induced histological, biochemical and hematological alterations in mice offspring.
Al-Basher, G., J.S. Ajarem, A.A. Allam and A.M. Mahmoud,
Int. J. Pharmacol., | Journal Article
Self Ayman Moawad Mahmoud
2017
Possible involvement of the JAK/STAT signaling pathway in N-acetylcysteine-mediated antidepressant-like effects.
Al-Samhari, M.M., N.M. Al-Rasheed, S. Al-Rejaie, N.M. Al-Rasheed, I.H. Hasan, A.M. Mahmoud and N. Dzimiri,
Exp. Biol. Med., | Journal Article
Self Ayman Moawad Mahmoud
2016
Effect of cinnamaldehyde on the toxicity of cyclophosphamide in the testes of rats: Influence of pre- and post-treatment schedule.
Abd El-Reheem, E.S., A.M. Mahmoud, A.M. Abd El-Hameed and H.A. Soliman,
Nat. Sci., | Journal Article
Self Ayman Moawad Mahmoud
2016
18β-Glycyrrhetinic acid protects against methotrexate-induced kidney injury by up-regulating the Nrf2/ARE/HO-1 pathway and endogenous antioxidants.
Abd El-Twab, S.M., W.G. Hozayen, O.E. Hussein and A.M. Mahmoud,
Renal Failure, | Journal Article
Self Ayman Moawad Mahmoud
2016
Taurine and pioglitazone attenuate diabetes-induced testicular damage by abrogation of oxidative stress and up-regulation of the pituitary-gonadal axis.
Abd El-Twab, S.M., H.M. Mohamed and A.M. Mahmoud,
Can. J. Physiol. Pharmacol., | Journal Article
Self Ayman Moawad Mahmoud
2016
Sildenafil reduces ischemia/reperfusion testicular injury after torsion/detorsion in rats.
Abdel-Rahman, M.M., A.M. Mahmoud, N.M. Mostafa, M.E. Saleh and H.M. Eissa,
J. Applied Pharmaceut. Sci., | Journal Article
Self Ayman Moawad Mahmoud
2016
Spirulina versicolor improves insulin sensitivity and attenuates hyperglycemia-mediated oxidative stress in fructose-fed rats.
Hozayen, W.G., A.M. Mahmoud, H.A. Soliman and S.R. Mostafa,
J. Intercult. Ethnopharmacol., | Journal Article
Self Ayman Moawad Mahmoud
2016
Wheat germ oil attenuates cyclophosphamide-induced testicular injury in rats.
Mahmoud, A.M., H.A. Soliman, A.M. Abd El-Hameed and E.S. Abd El-Rehim,
World J. Pharm. Pharmaceut. Sci., | Journal Article
Self Ayman Moawad Mahmoud
2016
A phytochemical and computational study on flavonoids isolated from Trifolium resupinatum L. and their novel hepatoprotective activity.
Kamel, E.M., A.M. Mahmoud, S.A. Ahmed and A.M. Lamsabhi,
Food Funct., | Journal Article
Self Ayman Moawad Mahmoud
2016
Flavonoids as potential Wnt/β-catenin signaling modulators for colorectal cancer prevention.
Mahmoud, A.M. and O.E. Hussein,
Int. J. Food Nutr. Sci., | Journal Article
Self Ayman Moawad Mahmoud
2016
Hesperidin as a promising anti-diabetic flavonoid: the underlying molecular mechanism.
Mahmoud, A.M. and O.E. Hussein,
Int. J. Food Nutr. Sci., | Journal Article
Self Ayman Moawad Mahmoud
2016
Brown seaweeds protect against azoxymethane-induced hepatic repercussions through up-regulation of peroxisome proliferator-activated receptor gamma and attenuation of oxidative stress.
Abdella, E.M., A.M. Mahmoud and A.M. El-Derby,
Pharmaceut. Biol., | Journal Article
Self Ayman Moawad Mahmoud
2016
Ruta graveolens protects against isoniazid/rifampicin-induced nephrotoxicity through modulation of oxidative stress and inflammation.
Hussein, O.E., M.O. Germoush and A.M. Mahmoud,
Global J. Biotechnol. Biomater. Sci., | Journal Article
Self Ayman Moawad Mahmoud
2016
Silymarin and hydroethanolic extracts of Silybum marianum leaves and fruits attenuate diethylnitrosamine/phenobarbital-induced nephrotoxicity via their antioxidant and anti-inflammatory actions.
Ahmed, O.M., A.M. Mahmoud, S.F.A. Zid and N.Y. Saber,
Am. J. Biochem., | Journal Article
Self Ayman Moawad Mahmoud
2016
Sitagliptin attenuates cardiomyopathy by modulating the JAK/STAT signaling pathway in experimental diabetic rats.
Al-Rasheed, N.M., N.M. Al-Rasheed, I.H. Hasan, M.A. Al-Amin, H.N. Al-Ajmi and A.M. Mahmoud,
Drug Des. Dev. Ther., | Journal Article
Self Ayman Moawad Mahmoud
2016
Simvastatin prevents isoproterenol-induced cardiac hypertrophy through modulation of the JAK/STAT pathway.
Al-Rasheed, N.M., M.M. Al-Oteibi, R.Z. Al-Manee, S.A. Al-Shareef and N.M. Al-Rasheed et al.,
Drug Des. Dev. Ther., | Journal Article
Self Ayman Moawad Mahmoud
2015
Carnitine palmitoyltransferase-1 up-regulation by PPAR-β/δ prevents lipid-induced endothelial dysfunction.
Toral, M., M. Romero, R. Jimenez, A.M. Mahmoud and E. Barroso et al.,
Clin. Sci., | Journal Article
Self Ayman Moawad Mahmoud
2015
Hesperidin protects against diethylnitrosamine-induced nephrotoxicity through modulation of oxidative stress and inflammation.
Ahmed, R.R., A.M. Mahmoud, M.B. Ashour and A.M. Kamel,
Natl. J. Physiol. Pharm. Pharmacol., | Journal Article
Self Ayman Moawad Mahmoud
2015
Flavonoids as ligands for peroxisome proliferator-activated receptor γ.
Mahmoud, A.M.,
Int. J. Food Nutr. Sci., | Journal Article
Self Ayman Moawad Mahmoud
2015
Ruta graveolens and its active constituent rutin protect against diethylnitrosamine-induced nephrotoxicity through modulation of oxidative stress.
Mahmoud, A.M., R.R. Ahmed, H.A. Soliman and M. Salah,
J. Appl. Pharm. Sci., | Journal Article
Self Ayman Moawad Mahmoud
2015
Prunus armeniaca leaves extract protects against isoniazid and rifampicin induced nephrotoxicity through modulation of oxidative stress and inflammation.
Mahmoud, A.M., B.M. Morsy, D.S. Abdel-Hady and R.M. Samy,
Int. J. Food Nutr. Sci., | Journal Article
Self Ayman Moawad Mahmoud
2015
Protective effects of Turbinaria ornata and Padina pavonia against azoxymethane-induced colon carcinogenesis through modulation of PPAR gamma, NF-κB and oxidative stress.
Mahmoud, A.M., E.M. Abdella, A.M. El-Derby and E.M. Abdella,
Phytother. Res., | Journal Article
Self Ayman Moawad Mahmoud
2015
Anti-diabetic effects of Padina pavonia in fructose-induced diabetic rats.
Germoush, M.O., H.A. Elgebaly, S. Hassan and A.M. Mahmoud,
Aljouf Univ. Sci. Eng. J., | Journal Article
Self Ayman Moawad Mahmoud
2015
Significance of the hepatitis C virus core antigen testing as an alternate marker for hepatitis diagnosis in Egyptian patients.
Soliman, H.A., W.G. Hozayen, A.M. Mahmoud, N.A. Fayed and M.A. Abo-Seif,
Eur. Rev. Med. Pharmacol. Sci., | Journal Article
Self Ayman Moawad Mahmoud
2015
In vivo and in vitro antidiabetic effects of citrus flavonoids; a study on the mechanism of action.
Mahmoud, A.M., O.M. Ahmed, M.B. Ashour and A. Abdel-Moneim,
Int. J. Diabetes Dev. Countries, | Journal Article
Self Ayman Moawad Mahmoud
2015
Rapid detection of bovine-specific nucleic acid sequences in cow milk using polymerase chain reaction.
Osman, A.A., A.M. Mahmoud and A.S. Soliman,
Int. J. Nutr. Food Sci., | Journal Article
Self Ayman Moawad Mahmoud
2014
Antihyperglycemic effect of crude extracts of some Egyptian plants and algae.
Abouzid, S.F., O.M. Ahmed, R.R. Ahmed, A.M. Mahmoud, E. Abdella and M.B. Ashour,
J. Med. Food, | Journal Article
Self Ayman Moawad Mahmoud
2014
Preventive effect of Spirulina versicolor and Enteromorpha flexuosa ethanolic extracts against diethylnitrosamine/benzo(a)pyrene-induced hapatocarcinogencity in rats.
Ahmed, O.M., B.M. Ashour, H.E. Fahim, A.M. Mahmoud and N.A. Ahmed,
J. Int. Acad. Res. Multidisciplin., | Journal Article
Self Ayman Moawad Mahmoud
2014
Beneficial effects of milk kefir in patients with chronic hepatitis C virus infection.
Morsy, B.M., A.M. Mahmoud, M.I. Zanaty, A. Abdel-Moneim and M.A. Abo-Seif,
Int. J. Bioassays, | Journal Article
Self Ayman Moawad Mahmoud
2014
Ruta graveolens mitigates ammonium chloride-induced hyperammonemia by modulating antioxidant status and pro-inflammatory cytokines.
Mahmoud, A.M., M.O. Germoush and A.S. Soliman,
Life Sci. J., | Journal Article
Self Ayman Moawad Mahmoud
2014
Thymoquinone and curcumin attenuate gentamicin-induced renal oxidative stress, inflammation and apoptosis in rats.
Mahmoud, A.M., O.M. Ahmed and S.R. Galaly,
EXCLI J., | Journal Article
Self Ayman Moawad Mahmoud
2014
Anti-diabetic and insulin sensitizing effects of Padina pavonia and Turbenaria ornata in streptozotocin/nicotinamide diabetic rats.
Mahmoud, A.M., M.O. Germoush, H.A. Elgebaly, K.N.M. Elsayed, S. Hassan, N.M. Mousa and O.E. Hussein,
Asian J. Pharmaceut. Clin. Res., | Journal Article
Self Ayman Moawad Mahmoud
2014
Thymoquinone and curcumin prevent gentamicin-induced liver injury by attenuating oxidative stress, inflammation and apoptosis.
Galaly, S.R., O.M. Ahmed and A.M. Mahmoud,
J. Physiol. Pharmacol., | Journal Article
Self Ayman Moawad Mahmoud
2014
Therapeutic effects of low-level laser and reflexology on adhesive capsulitis in elderly type 2 diabetic patients.
Soliman, A.S., A.M. Mahmoud, Z. Serry and F. Dawood,
Asian J. Pharmaceut. Clin. Res., | Journal Article
Self Ayman Moawad Mahmoud
2014
Berberine attenuates isoniazid-induced hepatotoxicity by modulating peroxisome proliferator-activated receptor γ, oxidative stress and inflammation.
Mahmoud, A.M., M.O. Germoush and A.S. Soliman,
Int. J. Pharmacol., | Journal Article
Self Ayman Moawad Mahmoud
2014
Brown seaweeds ameliorate renal alterations in mice treated with the carcinogen azoxymethane.
Mahmoud, A.M., A. El-Derby, K.N. Elsayed and E. Abdella,
Int. J. Pharm. Pharmaceut. Sci., | Journal Article
Self Ayman Moawad Mahmoud
2014
Hesperidin protects against cyclophosphamide-induced hepatotoxicity by upregulation of PPARγ and abrogation of oxidative stress and inflammation.
Mahmoud, A.M.,
Can. J. Physiol. Pharmacol., | Journal Article
Self Ayman Moawad Mahmoud
2014
Berberine mitigates cyclophosphamide-induced hepatotoxicity by modulating antioxidant status and inflammatory cytokines.
Germoush, M.O. and A.M. Mahmoud,
J. Cancer Res. Clin. Oncol., | Journal Article
Self Ayman Moawad Mahmoud
2014
Rutin attenuates hyperlipidemia and cardiac oxidative stress in diabetic rats.
Mahmoud, A.M. and A.S. Soliman,
Egypt. J. Med. Sci., | Journal Article
Self Ayman Moawad Mahmoud
2013
Bioinformatics analysis of functional genes and proteins for the diagnosis of obesity-induced type 2 diabetes.
Abdella, E.M., R.R. Ahmed, M.B. Ashour, O.M. Ahmed, S.F. Abu Zid and A.M. Mahmoud,
Int. J. Fundamental Applied Sci., | Journal Article
Self Ayman Moawad Mahmoud
2013
Sildenafil alleviates insulin sensitivity via attenuating oxidative stress and proinflammatory cytokines in diabetic rats.
Abou Riag, N.B.S., A.M. Mahmoud and S.A. Ramadan,
Int. J. Pharm. Bio. Sci., | Journal Article
Self Ayman Moawad Mahmoud
2013
Benificial therapeutic effects of Nigella sativa and Ginger officinalle in HCV patients in Egypt.
Abdel-Moneim, A., B.M. Morsy, A.M. Mahmoud, M.A. Abousief and M. Zanaty,
EXCLI J., | Journal Article
Self Ayman Moawad Mahmoud
2013
Upregulation of pparγ mediates the antidiabetic effects of citrus flavonoids in type 2 diabetic rats.
Mahmoud, A.M., O.M. Ahmed, A. Abdel-Moneim and M.B. Ashour,
Int. J. Bioassays, | Journal Article
Self Ayman Moawad Mahmoud
2013
Amelioration of cyclophosphamide-induced hepatotoxicity by the brown seaweed Turbenaria ornata.
Mahmoud, A.M., O.E. Hussein and S.A. Ramadan,
Studies, | Journal Article
Self Ayman Moawad Mahmoud
2013
Hematological alterations in diabetic rats: Role of adipocytokines and effect of citrus flavonoids.
Mahmoud, A.M.,
EXCLI J., | Journal Article
Self Ayman Moawad Mahmoud
2013
Ameliorative effects of sildenafil in acetic acid-induced chronic colitis in rats.
Ahmed, O.M., A. Afifi, T.M. Ali, S.A. Ramadan and A.M. Mahmoud,
Life Sci. J., | Journal Article
Self Ayman Moawad Mahmoud
2012
Antidiabetic effects of hesperidin and naringin in type 2 diabetic rats.
Ahmed, O.M., A.M. Mahmoud, A. Abdel-Moneim and M.B. Ashour,
Diabetologia Croatica, | Journal Article
Self Ayman Moawad Mahmoud
2012
Influence of rutin on biochemical alterations in hyperammonemia in rats.
Mahmoud, A.M.,
Exp. Toxicol. Pathol., | Journal Article
Self Ayman Moawad Mahmoud
2012
Hesperidin and naringin attenuate hyperglycemia-mediated oxidative stress and proinflammatory cytokine production in high fat fed/strptozotocin-induced type 2 diabetic rats.
Mahmoud, A.M., O.M. Ahmed, M.B. Ashour and A. Abdel-Moneim,
Diabetes Complications, | Journal Article
Self Ayman Moawad Mahmoud
2012
Antihyperglycemic and antihyperlipidemic effects of hesperidin and naringin in high fat diet/streptozotocin type 2 diabetic rats.
Ahmed, O.M., A.M. Mahmoud, A. Abdel-Moneim and M.B. Ashour,
Life Sci., | Journal Article
Self Ayman Moawad Mahmoud
2011
Insulin sensitizing effects of hesperidin and naringin in experimental model of induced type 2 diabetes in rats: Focus on tumor necrosis factor-alpha and Resistin.
Abdel-Moneim, A., M.B. Ashour, A.M. Mahmoud and O.M. Ahmed,
Nat. Sci., | Journal Article
Self Ayman Moawad Mahmoud
2011
Antihyperglycemic, antihyperlipidemic and antioxidant effects and the probable mechanisms of action of Ruta graveolens and rutin in Nicotinamide/streptozotocin diabetic albino rats.
Ahmed, O.M., A.A. Moneim, I.A. Yazid and A.M. Mahmoud,
Diabetol. Croatica, | Journal Article
Self Ayman Moawad Mahmoud
2010