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Magdy Mahfouz Youssef

Magdy Mahfouz Youssef

Professor
Mansoura University
LiveDNA ID: 20.3339
68 Publications
4 Editorial Roles
0 Projects

Employment

Professional Appointments
Professor
Mansoura University
Sep 1987 — Present | Mansoura, Egypt

Education

Academic Background
  • Ph.D. Bradford University, UK Molecular Biology and Genetics | Completed: 2002

Editorial Services

Editorial & Publishing Roles
Editorial Board Member
Oct 2011 — Present

Serving as Editorial Board Member for Asian Journal of Biochemistry.

Editorial Board Member
Oct 2011 — Present

Serving as Editorial Board Member for Asian Journal of Biological Sciences.

Editorial Board Member
Oct 2011 — Present

Serving as Editorial Board Member for American Journal of Biochemistry and Molecular Biology.

Editorial Board Member
Oct 2011 — Present

Serving as Editorial Board Member for Bacteriology Journal.

Publications (68)

Selected Scholarly Contributions
Association of HOTAIR gene polymorphisms and biochemical markers to uterine fibroids in Egyptian women.
Mona M. Gad, Hossam Abdel-Megeed Abdou, Magdy M. Youssef
Journal of Genetic Engineering and Biotechnology | Journal Article
Crossref
2026
Digitoxin as a novel synergistic partner of cisplatin in triple-negative breast cancer (TNBC) cells
Sara A. Al-Shun, Magdy M. Youssef, Farid A. Badria
Tumor Biology | Journal Article
Crossref
2026
Association of vitamin D receptor gene polymorphisms ApaI (rs7975232) and BsmI (rs1544410) with hepatocellular carcinoma susceptibility in Egyptian patients
Salma Saleh Alrdahe, Aishah E. Albalawi, Doaa Bahaa Eldin Darwish, Awatif M. E. Omran, Nada Mohammed Almasaudi, Afaf M. Elsaid, Magdy M. Youssef
Molecular Biology Reports | Journal Article
Crossref
2026
Binuclear Cr(III), Mn(II), and Zr(IV)O complexes with a novel isatin-based hydrazone ligand: Elucidation, computational and biological investigations
Ali H. Al-Hajooj, Mahdi A. Mohammed, Magdy M. Youssef, Gaber M. Abu El-Reash
Journal of Molecular Structure | Journal Article
Crossref
2026
Genetic insights into hepatocellular carcinoma: the role of VDR FokI (rs2228570) and TaqI (rs731236) polymorphisms in Egyptian patients
Salma Saleh Alrdahe, Doaa Bahaa Eldin Darwish, Aishah E. Albalawi, Awatif M. E. Omran, Nada Mohammed Almasaudi, Afaf M. Elsaid, Magdy M. Youssef
BMC Medical Genomics | Journal Article
Crossref
2026
Combining prognostic value of FGFR3 polymorphism and interleukin-1β status for enhanced prognostic stratification in bladder cancer
Afaf M. Elsaid, Riyad T. Mukhlif, Manar Abdelkhalek, Hassan Abol-Enein, Magdy M. Youssef
Comparative Clinical Pathology | Journal Article
Crossref
2026
New mixed-ligand complexes based on diethyl hydrazine-1,2-dicarboxylate and 2,2′-bipyridine: Synthesis, characterization, cyclic voltammetry and biological applications
Zeinab Salah, Magdy M. Youssef, Heba Youssef, Gaber M. Abu El-Reash
Journal of Molecular Structure | Journal Article
Crossref
2026
Synthesis, characterization and biological research of novel 2-(quinoline-4-carbonyl)hydrazide-acrylamide hybrids as potential anticancer agents on MCF-7 breast carcinoma cells by targeting EGFR-TK
Hany M. Abd El-Lateef, Duaa Bafail, Noura Hamdi Yousef Alhalees, Eslam E. M. Toson, Ali H. Abu Almaaty, Elsherbiny H. Elsayed, Islam Zaki, Magdy M. Youssef
RSC Advances | Journal Article
Crossref
2024
Co(II), Mn(II), and Fe(III) complexes of water‐soluble hydrazone bearing 2‐nicotinoylhydrazineylidene moiety: Preparation, characterization, cyclic voltammetry, computational and biological studies
Mahdi A. Mohammed, Ahmed Fetoh, Tamer Awad Ali, Magdy M. Youssef, Y. G. Abou El‐Reash, Gaber M. Abu El‐Reash
Applied Organometallic Chemistry | Journal Article
Crossref
2024
X‐ray crystallographic of a novel pyrimidine ligand (LPH) and its metal chelates Cr3+, Ni2+, and Ru3+: A comprehensive study on synthesis, characterization, computational investigations, and biological evaluation toward anticancer and antioxidant
Waleed H. Al‐Assy, Mohsen M. Mostafa, Stacey J. Smith, Roger Harrison, Magdy M. Youssef, Eman A. Hassan
Applied Organometallic Chemistry | Journal Article
Crossref
2024
Elucidation, cyclic voltammetry, computational studies, and biological activities of Ni(II), Cu(II), Cd(II), and Ce(III) complexes with a water‐soluble isonicotinohydrazide‐based Schiff base ligand
Mahdi A. Mohammed, Tamer Awad Ali, Magdy M. Youssef, Yasmeen G. Abou El‐Reash, Eida S. Al‐Farraj, Fatima A. Adam, A. A. El‐Moneim, Gaber M. Abu El‐Reash, Ahmed Fetoh
Applied Organometallic Chemistry | Journal Article
Crossref
2024
Association of interleukin6 rs1800796 gene polymorphism and serum level with bladder cancer in Egyptian population
Riyad T. Mukhlif, Hassan Abol-Enein, Afaf M. Elsaid, Manar Abdelkhalek, Heba H. Khatab, Magdy M. Youssef
Molecular Biology Reports | Journal Article
Crossref
2024
Fabrication of novel Fe (III), Co (II), Hg (II), and Pd (II) complexes based on water‐soluble ligand (NaH2PH): structural characterization, cyclic voltammetric, powder X‐ray diffraction, zeta potential, and biological studies
Mahdi A. Mohammed, Ahmed Fetoh, Tamer Awad Ali, Magdy M. Youssef, Gaber M. Abu El‐Reash
Applied Organometallic Chemistry | Journal Article
Crossref
2023
Investigation (IR, UV-visible, fluorescence, X-ray diffraction and thermogravimetric) studies of Mn(II), Fe(III) and Cr(III) complexes of thiosemicarbazone derived from 4- pyridyl thiosemicarbazide and monosodium 5-sulfonatosalicylaldehyde and evaluation of their biological applications
Ahmed Fetoh, Mahdi A. Mohammed, Magdy M. Youssef, Gaber M. Abu El-Reash
Journal of Molecular Structure | Journal Article
Crossref
2023
Synthesis of a new Cd (II) complex as ionophores and its application in construction of a highly selective and sensitive cadmium (II) sensor in petroleum water samples
Mahdi A. Mohammed, Ahmed Fetoh, Magdy M. Youssef, Gaber M. Abu El‐Reash, Y. G. Abou El‐Reash, Tamer Awad Ali
Applied Organometallic Chemistry | Journal Article
Crossref
2023
Structural variety of Co2+, Ni2+, Pd2+, and Pt4+ complexes of a hydrazone based on Girard's T: Synthesis, spectroscopic, molecular docking simulation on CTX‐M‐14 β‐lactamase, and theoretical (DFT) studies
Eman A. Hassan, Mohsen M. Mostafa, Stacey J. Smith, Roger Harrison, Magdy M. Youssef, Waleed H. Al‐Assy
Applied Organometallic Chemistry | Journal Article
Crossref
2023
Physicochemical studies of benzocaine bearing heterocycles as potential antioxidant agents.
Taha, I., E.M. Keshk, A.G.M. Khalil, M.M. Youssef and A. Fekri,
Polycyclic Aromat. Compd., | Journal Article
Self Magdy Mahfouz Youssef
2023
Down regulation of fatty acid synthase via inhibition of PI3K/AKT/mTOR in ovarian cancer cell line by novel organoselenium pseudopeptide
Abeer M. El-Saudi, Miram A. Altouhamy, Saad Shaaban, Farid A. Badria, Magdy M. Youssef, Fardous F. El-Senduny
Current Research in Pharmacology and Drug Discovery | Journal Article
Crossref
2022
PPARɣ2, aldose reductase, and TCF7L2 gene polymorphisms: Relation to diabetes mellitus.
Shawki, H.A., E.M. Abo-hashem, M.M. Youssef, M. Shahin and R. Elzehery,
J. Diabetes Metab. Disord., | Journal Article
Self Magdy Mahfouz Youssef
2022
Overexpression, biochemical characterization, and anticancer activates of L-asparaginase from Bacillus subtilis.
Darwish, D.B., S.S. Alrdahe, Y.S. Al-Awthan, I. Elfaki and T.M. Alnour et al.,
Int. J. Health Sci., | Journal Article
Self Magdy Mahfouz Youssef
2022
Anticancer activity of extremely effective recombinant L-asparaginase from Burkholderia pseudomallei.
Darwesh, D.B., Y.S. Al-Awthan, I. Elfaki, S.A. Habib, T.M. Alnour, A.B. Darwish and M.M. Youssef,
J. Microbiol. Biotechnol., | Journal Article
Self Magdy Mahfouz Youssef
2022
DNA barcoding of mammalian spermatozoa.
Hussein, Y.A., M.M. Youssef, A.M. Hereba, S.S. Al-Shokair and M.M. Waheed,
J. Camel Pract. Res., | Journal Article
Self Magdy Mahfouz Youssef
2021
Prunus armeniaca L. seed extract and its amygdalin containing fraction induced mitochondrial-mediated apoptosis and autophagy in liver carcinogenesis.
Hosny, S., H. Sahyon, M. Youssef and A. Negm,
Anti-Cancer Agents Med. Chem., | Journal Article
Self Magdy Mahfouz Youssef
2021
Association of GSTP1 p.Ile105Val (rs1695, c.313A > G) variant with the risk of breast carcinoma among Egyptian women.
Youssef, M.M., A.M. Elsaid, R.A. El-Saeed, R.T. Mukhlif, H. Megahed, A.I. Al-Alawy and R.M. Elshazli,
Biochem. Genet., | Journal Article
Self Magdy Mahfouz Youssef
2021
Oleanolic acid suppressed DMBA-induced liver carcinogenesis through induction of mitochondrial-mediated apoptosis and autophagy.
Hosny, S., H. Sahyon, M. Youssef and A. Negm,
Nutr. Cancer, | Journal Article
Self Magdy Mahfouz Youssef
2021
Evaluation of some oxidative markers in diabetes and diabetic retinopathy.
Shawki, H.A., R. Elzehery, M. Shahin, E.M. Abo-Hashem and M.M. Youssef,
Diabetology Int., | Journal Article
Self Magdy Mahfouz Youssef
2021
Protocatechuic acid decreased telomerase reverse transcriptase (TERT) expression in DMBA-induced liver carcinogenesis mice model.
El-Shaheed, S., H. Sahyon, M. Youssef and A. Negm,
Ann. Cancer Res. Ther., | Journal Article
Self Magdy Mahfouz Youssef
2020
Oxidative stress in CLL patients leads to activation of Th9 cells: An experimental and comprehensive survey.
Sabry, S.A., F.F. El-Senduny, N.K. Abousamra, M.S. El-Din and M.M. Youssef,
Immunol. Med., | Journal Article
Self Magdy Mahfouz Youssef
2020
Differential expression of HER2 and SKP2 in benign and malignant colorectal lesions.
Moussa, M., A. Badawy, N. Helal, F. Hegab and M. Youssef et al.,
Asian Pac. J. Cancer Prev., | Journal Article
Self Magdy Mahfouz Youssef
2020
Association of genetic polymorphisms of chemokines and their receptors with clearance or persistence of hepatitis C virus infection.
El-Bendary, M., M. Neamatallah, H. Elalfy, T. Besheer and M. El-Setouhy et al.,
Br. J. Biomed. Sci., | Journal Article
Self Magdy Mahfouz Youssef
2019
An approach to treatment of liver cancer by novel glycyrrhizin derivative.
El-Senduny, F.F., M.M. Zidane, M.M. Youssef and F.A. Badria,
Anti-Cancer Agents Med. Chem., | Journal Article
Self Magdy Mahfouz Youssef
2019
Acetyl glycyrrhetinic acid methyl ester as a promising glycyrrhizin derivative against the breast cancer cells (MCF-7).
Ibrahim, M.G., F.F. El-Senduny, M.M. Youssef, D.M. Elimam, F.M. Abdel Bar and F.A. Badria,
J. Rep. Pharm. Sci., | Journal Article
Self Magdy Mahfouz Youssef
2019
Prognostic Role of T Helper 9 Cells and Interleukin-9 in Chronic Lymphocytic Leukemia
Sabry A. Sabry, Fardous F. El-Send, Nashwa K. Abousam, Manal Salah EL-D, Magdy M. Youssef
American Journal of Biochemistry and Molecular Biology | Journal Article
Crossref
2018
ApolipoproteinC3 Gene Variants in Nonalcoholic Fatty Liver Disease in Egypt
Magdy M. Youssef, Amal Elshaer, Rizk Elbaz, Yehia A. Ellazek, Ahmad El-Waseef, Ahmad Settin
American Journal of Biochemistry and Molecular Biology | Journal Article
Crossref
2018
Synthesis, antimicrobial, DNA cleavage and antioxidant activities of tricyclic sultams derived from saccharin.
Elghamry, I., M.M. Youssef, M.A. Al-Omair and H. Elsawy,
Eur. J. Med. Chem., | Journal Article
Self Magdy Mahfouz Youssef
2017
Synthesis and biochemical studies of novel thiadiazoles.
Sayed, A.R., M.M. Youssef and S.S. Al-Shihry,
Curr. Org. Synth., | Journal Article
Self Magdy Mahfouz Youssef
2017
Photochemical and DNA degradation studies on tenoxicam, lornoxicam and their photolysis products.
Elghamry, I., U. El-Ayaan, M.M. Youssef, S. Al-Shihry, M. Letzel and J. Mattay,
Monatshefte fur Chemie-Chem. Monthly, | Journal Article
Self Magdy Mahfouz Youssef
2017
Synthesis and antiproliferative activity of monocationic arylthiophene derivatives.
Ismail, M.A., M.M. Youssef, R.K. Arafa, S.S. Al-Shihry and W.M. El-Sayed,
Eur. J. Med. Chem., | Journal Article
Self Magdy Mahfouz Youssef
2017
Synthesis, antimicrobial and antiproliferative activities of substituted phenylfuranylnicotinamidines.
Youssef, M.M., R.K Arafa and M. AIsmail,
Drug Des. Dev. Therapy, | Journal Article
Self Magdy Mahfouz Youssef
2016
Identifying the putative interacting partners of the heat shock protein, HtpG through phage display library screening.
Youssef, M.M. and M.A. Al-Omair,
Asian J. Biochem., | Journal Article
Self Magdy Mahfouz Youssef
2015
Synthesis, characterization and biological evaluation of novel thiadiazoline sulfonamides and metal complexes.
Sayed, A.R., M.M. Youssef and Y.S. Al-Faiyz,
J. Applied Sci., | Journal Article
Self Magdy Mahfouz Youssef
2015
Synthesis of novel triazoles, tetrazine, thiadiazoles and their biological activities.
Al-Omair, M.A., A.R. Sayed and M.M. Youssef,
Molecules, | Journal Article
Self Magdy Mahfouz Youssef
2015
Overexpression, purification, immobilization and characterization of thermophilic lipase from Burkholderia pseudomallei.
Youssef, M.M.,
Am. J. Microbiol. Biotechnol., | Journal Article
Self Magdy Mahfouz Youssef
2015
Antimicrobial and Antioxidant Activities of Artemisia abyssinica Extracts and DNA Degradation Effects
Magdy M. Youssef, Ahmed A. Mahmoud, Yasair S.S. Al-Faiyz
Asian J. Biochem., | Journal Article
Self Magdy Mahfouz Youssef
2015
Genetic characterization of Escherichia coli RecN protein as a member of SMC family of proteins.
Youssef, M.M., M.A. Al-Omair and S.M. Picksley,
Arab. J. Chem., | Journal Article
Self Magdy Mahfouz Youssef
2014
Identifying the polypeptide active partners and the dimer binding sites of HtpG protein applying 12 mer phage library.
Youssef, M.M. and M.A. Al-Omair,
Int. J. Curr. Microbiol. Applied Sci., | Journal Article
Self Magdy Mahfouz Youssef
2014
Anticancer, antioxidant activities and DNA affinity of novel monocationic bithiophenes and analogues.
Ismail, M.A., R.K. Arafa, M.M. Youssef and W.M. El-Sayed,
Drug Des. Dev. Therapy, | Journal Article
Self Magdy Mahfouz Youssef
2014
Synthesis and biological activity of drug delivery system based on chitosan nanocapsules.
Gouda, M., U. Elayaan and M.M. Youssef,
Adv. Nanoparticles, | Journal Article
Self Magdy Mahfouz Youssef
2014
Biochemical studies on the effects of zinc and lead on oxidative stress, antioxidant enzymes and lipid peroxidation in Okra (Hibiscus esculentus cv. Hassawi).
Youssef, M.M. and M.M. Azooz,
Sci. Int., | Journal Article
Self Magdy Mahfouz Youssef
2013
The potential role of seed priming with ascorbic acid and nicotinamide and their interactions to enhance salt tolerance in broad bean (Vicia faba L.).
Azooz, M.M., A.M. Alzahrani and M.M. Youssef,
Aust. J. Crop Sci., | Journal Article
Self Magdy Mahfouz Youssef
2013
Forensic biological identifications of mammal species through DNA barcodes.
Youssef, M.M., Y.A. Hussein, A.R. Heraba and S.S. Al-Shokair,
BioChem. Indian J., | Journal Article
Self Magdy Mahfouz Youssef
2012
Toxicity, antioxidative, antibacterial and biological activities of poisonous plants of al-hassa.
Youssef, M.M., Y.A. Hussein, S.S. Al-Shokair, S.R. Ghodake and A.N. Suryakar et al.,
BioChem. Indian J., | Journal Article
Self Magdy Mahfouz Youssef
2012
Synthesis, DNA affinity and antimicrobial activity of 4-substituted phenyl-2,2'-bichalcophenes and aza-analogues.
Youssef, M.M., M.A. Al-Omair and M.A. Ismail,
Med. Chem. Res., | Journal Article
Self Magdy Mahfouz Youssef
2012
Comparative evaluation of zinc and lead and their synergistic effects on growth and some physiological responses of Hassawi Okra (Hibiscus esculentus) seedlings.
Azooz, M.M., M.M. Youssef and M.A. Al-Omair,
Am. J. Plant Physiol., | Journal Article
Self Magdy Mahfouz Youssef
2011
Polyacrylamide Gel Electrophoresis of Proteins Extracted from Nematotaenia Dispar which Isolated from Varanus griseus in Saudi Arabia.
Al-Mohammed, H.I. and M.M. Youssef,
Res. J. Biol. Sci., | Journal Article
Self Magdy Mahfouz Youssef
2010
Evaluation of heat shock and salicylic acid treatments as inducers of drought stress tolerance in hassawi wheat.
Azooz, M.M. and M.M. Youssef,
Am. J. Plant Physiol., | Journal Article
Self Magdy Mahfouz Youssef
2010
Value of α-smooth muscle actin and glial fibrillary acidic protein in predicting early hepatic fibrosis in chronic hepatitis C virus infection.
Zakaria, S., M. Youssef, M. Moussa, M. Akl and E. El-Ahwany et al.,
Arch. Med. Sci., | Journal Article
Self Magdy Mahfouz Youssef
2010
Mn(II), Co(II), Zn(II), Fe(III) and U (VI) complexes of 2-acetylpyridine 4N-(2-pyridyl) thiosemicarbazone (HAPT); structural, spectroscopic and biological studies.
El-Ayaan, U., M.M. Youssef and S. Al-Shihry,
J. Mol. Struct., | Journal Article
Self Magdy Mahfouz Youssef
2009
Chemical composition and effect of photo-oxygenation on biological activities of Egyptian commercial anise and fennel essential oils.
Dawidar, A.M., M. Abdel-Mogib, A.M. El-Ghorab, M. Mahfouz, F.G. El-Said and K. Hussien,
J. Essential Oil-Bearing Plants, | Journal Article
Self Magdy Mahfouz Youssef
2008
Biochemical studies on the effect of selenium and α-difluromethylornithine on the elevated polyamines in mice.
Al-Omair, M.A. and M.M. Youssef,
J. Biol. Sci., | Journal Article
Self Magdy Mahfouz Youssef
2008
Inducers and inhibitors of laccase from Penicillium.
El-Shora, H.M., M.M. Youssef and A.S. Khalaf,
Biotechnology, | Journal Article
Self Magdy Mahfouz Youssef
2008
Cloning, purification, characterization and immobilization of L-asparaginase II from E. coli W3110.
Youssef, M.M. and M.A. Al-Omair,
Asian J. Biochem., | Journal Article
Self Magdy Mahfouz Youssef
2008
Identification of catalytically essential amino acid residues and immobilization of glutamate dehydrogenase from Rumex cotyledons.
El-Shora, H.M. and M.M. Youssef,
Asian J. Biochem., | Journal Article
Self Magdy Mahfouz Youssef
2008
Perchlorate mixed-ligand copper(II) complexes of beta-diketone and ethylene diamine derivatives: Thermal, spectroscopic and biochemical studies.
El-Ayaan, U., N.M. El-Metwally, M.M. Youssef and S.A.A. El-Bialy,
Spectrochim. Acta A Mol. Biomol. Spectrosc., | Journal Article
Self Magdy Mahfouz Youssef
2007
Site directed mutagensis in Walker A nucleotide binding site of SbcC protein of E. coli.
Youssef, M.M. and S.A. Habib,
Egypt. J. Biomed.Sci., | Journal Article
Self Magdy Mahfouz Youssef
2006
Induction and immobilization of asparaginase from Aspergillus niger.
El-Shora, H.M., M.M. Youssef and A.K. Salwa,
Biochem. Lett., | Journal Article
Self Magdy Mahfouz Youssef
2005
Biochemical properties and immobilization of phytase from Penicillium digitatum.
El-Shora, H.M., S.A. Khalaf and M.M. Youssef,
Mans. Sci. Bull., | Journal Article
Self Magdy Mahfouz Youssef
2004
The toxic effects of cadmium and copper on the antioxidative enzymes and lipid peroxidation in marrow roots.
El-Shora, H.M., E.M. Abo-Kassem and M.M. Youssef,
Mans. Sci. Bull., | Journal Article
Self Magdy Mahfouz Youssef
2004