Dr. Najeeb Ur Rehman
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Dr. Najeeb Ur Rehman

Assistant Professor
Prince Sattam Bin Abdulaziz University, Saudi Arabia

Highest Degree
Ph.D. in Gastrointestinal and Airways Pharmacology from University of Karachi, Pakistan

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Area of Interest:

Pharmacology and Toxicology
100%
Gastrointestinal Pharmacology
62%
Natural Product Pharmacology
90%
Toxicity studies
75%
Pathology
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
0
Abstracts
0

Selected Publications

  1. Ansari, M.N., N.U. Rehman, A. Karim, T. Bahta, K.Y. Abujheisha, S.R. Ahamad and F. Imam, 2020. Evaluation of Bronchodilator and antimicrobial activities of Otostegia fruticose: A multi-mechanistic approach. Saudi Pharm. J., 10.1016/j.jsps.2020.01.007.
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  2. Yimer, E.M., K.B. Tuem, A. Karim, N. Ur-Rehman and F. Anwar, 2019. Nigella sativa L. (black cumin): A promising natural remedy for wide range of illnesses. Evidence-Based Complement. Altern. Med., Vol. 2019. 10.1155/2019/1528635.
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  3. Naz, M., N. Rehman, M.N. Ansari, M. Kamal, M.A. Ganaie, A.S. Awaad and S.I. Alqasoumi, 2019. Comparative study of subchronic toxicities of mosquito repellents (coils, mats and liquids) on vital organs in Swiss albino mice. Saudi Pharm. J., 27: 348-353.
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  4. Madkhali, H.A., K.M. Alharthy, M.A. Asiri, M.A. Ganaie, M.N. Ansari, N.U. Rehman and A.M. Hamad, 2019. Moringa oleifera Lam. (family Moringaceae) leaf extract attenuates high-fat diet-induced dyslipidemia and vascular endothelium dysfunction in Wistar albino rats. Trop. J. Pharm. Res., 18: 2597-2604.
  5. Khan, A., Najeeb-ur-Rehman, A.H. Gilani, Z. Ahmed, S. Al-Massarani, A. El-Gamal and M. Farag, 2019. Possible mechanism(s) underlying the antidiarrheal, antispasmodic and bronchodilatory activities of the pericarp of Albizia lebbeck. Int. J. Pharmacol., 15: 56-65.
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  6. Anwar, F., A. Abbas, T. Mehmood, A.H. Gilani and N.U. Rehman, 2019. Mentha: A genus rich in vital nutra‐pharmaceuticals-A review. Phytother. Res., 33: 2548-2570.
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  7. Ansari, M.N., R.I. Aloliet, M.A. Ganaie, T.H. Khan, Najeeb-ur-Rehman, F. Imam and A.M. Hamad, 2019. Roflumilast, a phosphodiesterase 4 inhibitor, attenuates cadmium-induced renal toxicity via modulation of NF-κB activation and induction of NQO1 in rats. Hum. Exp. Toxicol., 38: 588-597.
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  8. Ansari, M.N., M.A. Ganaie, N.U. Rehman, K.M. Alharthy and T.H. Khan et al., 2019. Protective role of Roflumilast against cadmium-induced cardiotoxicity through inhibition of oxidative stress and NF-κB signaling in rats. Saudi Pharm. J., 27: 673-681.
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  9. Aslam, H., A.U. Khan, Najeeb-ur-Rehman, F. Ali, H. Nadeem and S.M. Shah, 2017. Anti-hyperglycemic activity of Heliotropium strigosum (Boraginaecae) whole plant extract in alloxan-induced diabetic mice. Trop. J. Pharmaceut. Res., 16: 2425-2430.
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  10. Anwar, F., K.M. Alkharfy, Najeeb-ur-Rehman, E.H.K. Adam and A.U.H. Gilani, 2017. Chemo-geographical variations in the composition of volatiles and the biological attributes of Mentha longifolia (L.) essential oils from Saudi Arabia. Int. J. Pharmacol., 13: 408-424.
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  11. Khan, H., M. Saeed, A.H. Gilani, N. Muhammad, N.U. Rehman, M.H. Mehmood and N. Ashraf, 2016. Antispasmodic and antidiarrheal activities of rhizomes of Polygonatum verticillatum maneuvered predominately through activation of K+ channels: Components identification through TLC. Toxicol. Ind. Health, 32: 677-685.
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  12. Arshad, U., S. Bashir, Najeeb-ur-Rehman, T. Yaqub and A.H. Gilani, 2016. Dual inhibition of Ca+2 influx and phosphodiesterase enzyme provides scientific base for the medicinal use of Chrozophora prostrata Dalz. in respiratory disorders. Phytother. Res., 30: 1010-1015.
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  13. Rehman, N.U., A.H. Gilani, A. Khan, M. Nazneen and A.A. El Gamal, 2015. Antidiarrheal and antispasmodic activities of Buddleja polystachya are mediated through dual inhibition of Ca++ influx and phosphodiesterase enzyme. Phytother. Res., 29: 1211-1218.
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  14. Palla, A.H., N.A. Khan, S. Bashir, Najeeb-ur-Rehman, J. Iqbal and A.H. Gilani, 2015. Pharmacological basis for the medicinal use of Linum usitatissimum (Flaxseed) in infectious and non-infectious diarrhea. J. Ethnopharmacol., 160: 61-68.
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  15. Khan, M., K. Arif-ullah, N. Rehman and A.H. Gilani, 2015. Blood pressure lowering, vasodilator and cardiac-modulatory potential of Carum roxburghianum seed extract. Clin. Exp. Hypertens., 37: 102-107.
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  16. Gilani, A.H., N.U. Rehman, A. Khan and K.M. Alkharfy, 2015. Studies on bronchodilator activity of Salvia officinalis (Sage): Possible involvement of K+ channel activation and phosphodiesterase inhibition. Phytother. Res., 29: 1323-1329.
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  17. Aleem, A., K.H. Janbaz, M.H. Mehmood, S. Bashir, F. Jawed, Najeeb-ur-Rehman and A.H. Gilani, 2015. Pharmacological studies on antidiarrheal, gut modulatory, bronchodilatory and vasodilatory activities of Myrica nagi. Int. J. Pharmacol., 11: 888-898.
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  18. Khan, M., A.U. Khan, Najeeb‐ur‐ Rehman and A.H. Gilani, 2014. Pharmacological basis for the medicinal use of Lens culinaris in gastrointestinal and respiratory disorders. Phytother. Res., 28: 1349-1358.
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  19. Khan, M., A.U. Khan, Najeeb-ur-Rehman and A.H. Gilani, 2014. Blood pressure lowering effect of Morus alba is mediated through Ca++ antagonist pathway. Int. J. Pharmacol., 10: 225-230.
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  20. Khan, M., A.U. Khan, N.U. Rehman and A.H. Gilani, 2014. Cardiovascular inhibitory properties of Lens culinaris. Bangladesh J. Pharmacol., 9: 303-306.
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  21. Rehman, N.U., K. Aslam, F. Urooj, A. Mahrukh and A.M. Nawal et al., 2013. Presence of laxative and antidiarrheal activities in Periploca aphylla: A Saudi medicinal plant. Int. J. Pharmacol., 9: 190-196.
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  22. Muhammad, N., N.U. Rehman, H. Khan, M. Saeed and A.H. Gilani, 2013. Prokinetic and laxative effects of the crude methanolic extract of Viola betonicifolia whole plant in rodents. BMC Complement. Altern. Med., Vol. 13. 10.1186/1472-6882-13-70.
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  23. Mehmood, M.H., A. Rehman, N. Rehman and A.H. Gilani, 2013. Studies on prokinetic, laxative and spasmodic activities of Phyllanthus emblica in experimental animals. Phytother. Res., 27: 1054-1060.
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  24. Khan, H., M. Saeed, M.H. Mehmood, N.U. Rehman and N. Muhammad et al., 2013. Studies on tracheorelaxant and anti-inflammatory activities of rhizomes of Polygonatum verticillatum. BMC Complement. Altern. Med., Vol. 13. 10.1186/1472-6882-13-197.
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  25. Khan, H., M. Saeed, A.H. Gilani, N. Muhammad and I.U. Haq et al., 2013. Antipyretic and anticonvulsant activity of Polygonatum verticillatum: Comparison of rhizomes and aerial parts. Phytother. Res., 27: 468-471.
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  26. Khan, H., M. Saeed, A.H. Gilani, M.H. Mehmood and Najeeb-ur-Rehman et al., 2013. Bronchodilator activity of aerial parts of Polygonatum verticillatum augmented by anti‐inflammatory activity: Attenuation of Ca2+ channels and lipoxygenase. Phytother. Res., 27: 1288-1292.
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  27. Gilani, A.H., N. Rehman, M.H. Mehmood and K.M. Alkharfy, 2013. Species differences in the antidiarrheal and antispasmodic activities of Lepidium sativum and insight into underlying mechanisms. Phytother. Res., 27: 1086-1094.
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  28. Siddiqi, H.S., M.H. Mehmood, N.U. Rehman and A.H. Gilani, 2012. Studies on the antihypertensive and antidyslipidemic activities of Viola odorata leaves extract. Lipids Health Dis., Vol. 11. 10.1186/1476-511X-11-6.
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  29. Najeeb-ur-Rehman, M.H. Mehmood, K.M. Alkharfy and A.H. Gilani, 2012. Studies on antidiarrheal and antispasmodic activities of Lepidium sativum crude extract in rats. Phytother. Res., 26: 136-141.
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  30. Najeeb-ur-Rehman, M.H. Mehmood, A.J. Al-Rehaily, R.A.A. Mothana and A.H. Gilani, 2012. Species and tissue-specificity of prokinetic, laxative and spasmodic effects of Fumaria parviflora. BMC Complementary Altern. Med., Vol. 12. 10.1186/1472-6882-12-16.
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  31. Najeeb-ur-Rehman, K. Arif-ullah, K.M. Alkharfy and A.H. Gilani, 2012. Pharmacological basis for the medicinal use of Lepidium sativum in airways disorders. Evidence-Based Complement. Altern. Med., Vol. 2012. 10.1155/2012/596524.
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  32. Najeeb-Ur-Rehman, S. Bashir, A.J. Al-Rehaily and A.H. Gilani, 2012. Mechanisms underlying the antidiarrheal, antispasmodic and bronchodilator activities of Fumaria parviflora and involvement of tissue and species specificity. J. Ethnopharmacol., 144: 128-137.
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  33. Khan, M., N. Rehman, A. Khan and A.H. Gilani, 2012. Pharmacological basis for the medicinal use of Morus alba in gut and airways disorders. Bangladesh J. Pharmacol., 7: 289-298.
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  34. Khan, M., A.U. Khan, Najeeb-ur-Rehman, M.A. Zafar, A. Hazrat and A.H. Gilani, 2012. Cardiovascular effects of Juniperus excelsa are mediated through multiple pathways. Clin. Exp. Hypertens., 34: 209-216.
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  35. Khan, M., A. Khan, N. Rehman and A.H. Gilani, 2012. Pharmacological explanation for the medicinal use of Juniperus excelsa in hyperactive gastrointestinal and respiratory disorders. J. Nat. Med., 66: 292-301.
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  36. Khan, M., A. Khan, N. Rehman and A.H. Gilani, 2012. Gut and airways relaxant effects of Carum roxburghianum. J. Ethnopharmacol., 141: 938-946.
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  37. Khan, A., Najeeb-ur-Rehman, A.M. Al-Taweel, S. Perveen, G.A. Fawzy and A.H. Gilani, 2012. Studies on prokinetic, laxative, antidiarrheal and gut modulatory activities of the aqueous-methanol extract of Celtis Africana and underlying mechanisms. Int. J. Pharmacol., 8: 701-707.
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  38. Chaudhary, M.A., I. Imran, S. Bashir, M.H. Mehmood, N.U. Rehman and A.H. Gilani, 2012. Evaluation of gut modulatory and bronchodilator activities of Amaranthus spinosus Linn. BMC Complem. Altern. Med., Vol. 12. 10.1186/1472-6882-12-166.
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  39. Arshad, U., K.H. Janbaz, S. Bashir, Najeeb-ur-Rehman, M.H. Mehmood and A.H. Gilani, 2012. Ethnopharmacological studies on Chrozophora prostrata in perspective of its folkloric reputation as purgative. Bangladesh J. Pharmacol., 7: 243-248.
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  40. Najeeb-ur-Rehman, M.H. Mehmood, K.M. Alkharfy and A.H. Gilani, 2011. Prokinetic and laxative activities of Lepidium sativum seed extract with species and tissue selective gut stimulatory actions. J. Ethnopharmacol., 134: 878-883.
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  41. Khan, A., Najeeb-ur-Rehman, K.M. AlKharfy and A.H. Gilani, 2011. Antidiarrheal and antispasmodic activities of Salvia officinalis are mediated through activation of K+ channels. Bangladesh J. Pharmacol., 6: 111-116.
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  42. Khan, A., A.H. Gilani and Najeeb-ur-Rehman, 2011. Pharmacological studies on Hypericum perforatum fractions and constituents. Pharm. Biol., 49: 46-56.
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  43. Shah, A.J., N.N. Bhulani, S.H. Khan, N. Rehman and A.H. Gilani, 2010. Calcium channel blocking activity of Mentha longifolia L. explains its medicinal use in diarrhoea and gut spasm. Phytother. Res., 24: 1392-1397.
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  44. Gilani, A.H., S.U.R. Mandukhail, J. Iqbal, M. Yasinzai, N. Aziz, A. Khan and Najeeb-ur-Rehman, 2010. Antispasmodic and vasodilator activities of Morinda citrifolia root extract are mediated through blockade of voltage dependent calcium channels. BMC Complement. Altern. Med., Vol. 10. 10.1186/1472-6882-10-2.
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  45. Gilani, A.H., A. Khan, A. Khan, S. Bashir and N. Rehman et al., 2010. Pharmacological basis for the medicinal use of Holarrhena antidysenterica in gut motility disorders. Pharm. Biol., 48: 1240-1246.
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