About
Professional Summary
I am working as an Associate Professor in the Department of Zoology, University of Madras, Guindy Campus, Chennai, India. At present, I am involving in the toxicological research about the organ toxic effects of heavy metals and their chelation by phytoconstituents. I have published more than 83 international peer-reviewed papers, 7 book chapters and 5 books with a total impact factor 158.25 and I have organized two national conferences and workshops in environmental toxicology and completed one UGC Major research project in toxicology. I have guided 5 Ph.d's and 19 M.Phil Scholars. I am serving as a editorial member of more than 15 journals. I have reviewed more than 300 peer referred articles in almost all the leading scientific publication services including Nature, Frontiers, wiley, blackwell, springer, elsevier, sage, rsc, acs, crs, blackwell-synergy, bentham etc.
Education
Academic Background
Publications (72)
Selected Scholarly Contributions
Biochemical and histological alterations induced by UV-328 in the gill tissue of Zebra fish (Danio rerio) and its reversal by Dimethoxy curcumin
S. Senthilmurugan, S. Miltonprabu
Journal of Drug Delivery and Therapeutics
| Journal Article
2024
Sulforaphane potentially attenuates arsenic-induced nephrotoxicity via the PI 3 K/Akt/Nrf 2 pathway in albino Wistar rats.
Thangapandiyan, S., R. Mathan, M. Selvaraj, H. Tamilselvan, B.J. Gunasekaran and N. Venkatesan,
Environ. Sci. Pollut. Res.,
| Journal Article

S. Milton Prabu
2019
The molecular and biochemical insight view of grape seed proanthocyanidins in ameliorating cadmium-induced testes-toxicity in rat model: Implication of pi3k/akt/nrf-2 signaling.
Bashir, N., S. Kalist, M. Vaikundam and M. Selvaraj,
Biosci. Rep.,
| Journal Article

S. Milton Prabu
2019
Protective role of pterostilbene against sodium fluoride induced plasma toxicity in rats: An in-vitro and in-vivo study.
Prabu, S.M., S. Saranya, S. Thangapandiyan and V. Manoharan,
Asian J. Phytomed. Clin. Res.,
| Journal Article

S. Milton Prabu
2018
Histopathological and biochemical changes in grass carp gill and muscle tissues due to nickel exposure may be related to the induction of oxidative stress.
Shagirtha, K., Priya, Arthi, Arun and P.S. Milton,
Eur. J. Biomed. Pharm. Sci,
| Journal Article

S. Milton Prabu
2018
A mechanism underlying the neurotoxicity induced by sodium fluoride and its reversal by epigallocatechin gallate in the rat hippocampus: Involvement of nrf 2 /Keap-1 signaling pathway.
Shanmugam, T., S. Abdulla, V. Yakulasamy, S. Miltonprabu and M. Ramesh,
J. Basic Appl. Zool.,
| Journal Article

S. Milton Prabu
2018
Diallyl trisulfide, a garlic polysulfide protects against As-induced renal oxidative nephrotoxicity, apoptosis and inflammation in rats by activating the Nrf2/ARE signaling pathway.
Miltonprabu, S., N.C. Sumedha and P. Senthilraja,
Int. Immunopharmacol.,
| Journal Article

S. Milton Prabu
2017
Hepatoprotective effect of grape seed proanthocyanidins on Cadmium-induced hepatic injury in rats: Possible involvement of mitochondrial dysfunction, inflammation and apoptosis
Selvaraj Miltonprabu, Nazimabashir, Vaihundam Manoharan
Toxicology Reports
| Journal Article
2016
Epigallocatechin gallate potentially abrogates fluoride induced lung oxidative stress, inflammation via Nrf2/Keap1 signaling pathway in rats: An in-vivo and in-silico study.
Shanmugam, T., M. Selvaraj and S. Poomalai,
Int. Immunopharmacol.,
| Journal Article

S. Milton Prabu
2016
Defensive role of silibinin against arsenic induced oxidative stress mediated dyslipidemia and neurotoxicity in rats.
Muthu, M., S.N. Chanu, S. Kalist and M. Prabu,
Int. J. Pharmacol. Toxicol.,
| Journal Article

S. Milton Prabu
2016
Grape seed proanthocyanidins protects against cadmium induced oxidative pancreatitis in rats by attenuating oxidative stress, inflammation and apoptosis via Nrf-2/HO-1 signaling.
Bashir, N., V. Manoharan and S. Miltonprabu,
J. Nutr. Biochem.,
| Journal Article

S. Milton Prabu
2016
Rutin rescues cadmium induced oxidative stress mediated myocardial toxicity and dyslipidemia in rats.
Shagirtha, K., N.C. Sumedha and S. Miltonprabu,
J. Free Radicals Antioxidants,
| Journal Article

S. Milton Prabu
2016
Cadmium and apoptosis: A molecular approach.
Shagirtha, K. and S. Miltonprabu,
Res. Rev.: J. Toxicol.,
| Journal Article

S. Milton Prabu
2016
Oxidative stress induced by cadmium in the plasma, erythrocytes and lymphocytes of rats: Attenuation by grape seed proanthocyanidins.
Nazima, B., V. Manoharan and S. Miltonprabu,
Hum. Exp. Toxicol.,
| Journal Article

S. Milton Prabu
2016
Cadmium induced cardiac oxidative stress in rats and its attenuation by GSP through the activation of Nrf2 signaling pathway.
Nazimabashir, M.V. and S. Miltonprabu,
Chem. Biol. Interact,
| Journal Article

S. Milton Prabu
2015
Epigallocatechin gallate exacerbates fluoride-induced oxidative stress mediated testicular toxicity in rats through the activation of Nrf2 signaling pathway.
Thangapandiyan, S. and S. Miltonprabu,
Asian Pacific J. Reprod.,
| Journal Article

S. Milton Prabu
2015
Ameliorative efficacy of tetrahydrocurcumin against arsenic induced oxidative damage, dyslipidemia and hepatic mitochondrial toxicity in rats.
Muthumani, M. and S. Miltonprabu,
Chemico-Biol. Interactions,
| Journal Article

S. Milton Prabu
2015
Cardiac mitochondrial oxidative stress and dysfunction induced by arsenic and its amelioration by diallyl trisulphide.
Sumedha, N.C. and S. Miltonprabu,
Toxicol. Res.,
| Journal Article

S. Milton Prabu
2015
Epigallocatechin gallate potentially attenuates Fluoride induced oxidative stress mediated cardiotoxicity and dyslipidemia in rats.
Miltonprabu, S. and S. Thangapandiyan,
J. Trace Elements Med. Biol.,
| Journal Article

S. Milton Prabu
2015
Diallyl trisulfide ameliorates arsenic induced dyslipidemia in rats.
Miltonprabu, S. and N.C. Sumedha,
Food Sci. Biotechnol.,
| Journal Article

S. Milton Prabu
2015
Diallyl trisulfide ameliorates arsenic-induced hepatotoxicity by abrogation of oxidative stress, inflammation and apoptosis in rats.
Sumedha, N.C. and S. Miltonprabu,
Hum. Exp. Toxicol.,
| Journal Article

S. Milton Prabu
2015
Grape seed proanthocyanidins ameliorates cadmium-induced renal injury and oxidative stress in experimental rats through the up-regulation of nuclear related factor 2 and antioxidant responsive elements.
Nazima, B., V. Manoharan and S. Miltonprabu,
Biochem. Cell Biol.,
| Journal Article

S. Milton Prabu
2014
Cadmium toxicity: Oxidative stress and organ dysfunction.
Nazima, B. and V. Manoharan,
Res. Rev.: J. Toxicol.,
| Journal Article

S. Milton Prabu
2014
Dimethoxycurcumin potentially protects arsenic induced oxidative hepatic injury, inflammation and apoptosis via Nrf2-Keap1 signaling in rats.
Miltonprabu, S. and M. Muthumani,
Biomed. Preventive Nutr.,
| Journal Article

S. Milton Prabu
2014
Epigallocatechin gallate supplementation protects against renal injury induced by Fluoride intoxication in rats: Role of Nrf2/HO-1 signaling.
Thangapandiyan, S. and S. Miltonprabu,
Toxicol. Rep.,
| Journal Article

S. Milton Prabu
2014
Ameliorative effect of EGCG on sodium fluoride induced oxidative stress mediated metabolism in rats.
Thangapandiyan, S. and S.M. Prabu,
Int. J. Pharmacol. Toxicol.,
| Journal Article

S. Milton Prabu
2014
Ameliorative effects of grape seed proanthocyanidins on cadmium induced metabolic alterations in rats.
Bashir, N., V. Manoharan and S.M. Prabu,
Int. J. Biol. Res.,
| Journal Article

S. Milton Prabu
2014
Endosulfan-Induced hepatotoxicity and its amelioration by administration of bamboo (Dendrocalamus strictus) seed extract in rats.
Sumedha, N.C., S. Achiraman, K. Rajaganesh and S.M. Prabu,
Res. Rev.: J. Toxicol.,
| Journal Article

S. Milton Prabu
2014
Diallyl trisulfide (DATS) abrogates arsenic induced testicular oxidative stress in rats.
Prabu, S.M. and N. Sumedha,
Int. J. Pharmacol. Toxicol.,
| Journal Article

S. Milton Prabu
2014
Arsenic-induced hepatic mitochondrial toxicity in rats and its amelioration by diallyl trisulfide.
Miltonprabu, S. and N.C. Sumedha,
Toxicol. Mechanisms Methods,
| Journal Article

S. Milton Prabu
2014
Ameliorative effect of diallyl trisulphide on arsenic-induced oxidative stress in rat erythrocytes and DNA damage in lymphocytes.
Prabu, S.M. and N.C. Sumedha,
J. Basic Clin. Physiol. Pharmacol.,
| Journal Article

S. Milton Prabu
2014
Arsenic induced oxidative hematotoxicity in rats and its protection by diallyl trisulfide.
Sumedha, N.C. and S. Miltonprabu,
Int. J. Biol. Pharm. Res.,
| Journal Article

S. Milton Prabu
2013
Antioxidant efficacy of diallyl trisulfide on arsenic-induced toxicity in rats: An in vivo and in vitro study.
Sumedha, N.C. and S. Miltonprabu,
Int. J. Toxicol. Applied Pharmacol.,
| Journal Article

S. Milton Prabu
2013
Protective role of bamboo (Dendrocalamus strictus) seed extract on endosulfan treated male rat testes and fertility.
Sumedha, N.C., S. Achiraman, K. Rajaganesh and S.M. Prabu,
Int. J. Curr. Res.,
| Journal Article

S. Milton Prabu
2013
Protective effect of epigallocatechin gallate (EGCG) on sodium fluoride (NaF) induced changes in histology of selected organs in rats.
Thangapandiyan, S. and S.M. Prabu,
Res. Rev.: J. Toxicol.,
| Journal Article

S. Milton Prabu
2013
An in vivo and in vitro studies on the antioxidant property of epigallocatechin gallate on sodium fluoride induced toxicity in rats.
Thangapandiyan, S. and S. Miltonprabu,
Int. J. Phytopharmacol.,
| Journal Article

S. Milton Prabu
2013
Epigallocatechin gallate effectively ameliorates fluoride-induced oxidative stress and DNA damage in the liver of rats.
Thangapandiyan, S. and S. Miltonprabu,
Can. J. Physiol. Pharmacol.,
| Journal Article

S. Milton Prabu
2013
Silibinin attenuates arsenic induced alterations in serum and hepatic lipid profiles in rats.
Muthumani, M. and P.S. Milton,
J. Applied Pharm. Sci.,
| Journal Article

S. Milton Prabu
2013
Quercetin potentially attenuates cadmium induced oxidative stress mediated cardiotoxicity and dyslipidemia in rats.
Prabu, S.M., M. Muthumani and K. Shagirtha,
Eur. Rev. Med. Pharmacol. Sci.,
| Journal Article

S. Milton Prabu
2013
Silibinin ameliorates oxidative stress mediated testicular damage by arsenic in rats.
Muthumani, M. and S. Miltonprabu,
Asian Pacific J. Trop. Biomed.,
| Journal Article

S. Milton Prabu
2012
Silibinin ameliorates arsenic induced nephrotoxicity by abrogation of oxidative stress, inflammation and apoptosis in rats.
Prabu, S.M. and M. Muthumani,
Mol. Biol. Rep.,
| Journal Article

S. Milton Prabu
2012
Arsenic induced oxidative stress and its possible reversal by chelation therapy.
Muthumani, M. and S. Miltonprabu,
J. Toxicol.,
| Journal Article

S. Milton Prabu
2012
Quercetin protects against cadmium-induced biochemical and structural changes in rat liver revealed by FT-IR spectroscopy.
Krishnakumar, N., S.M. Prabu and N.K. Sulfikkarali,
Biomed. Preventive Nutr.,
| Journal Article

S. Milton Prabu
2012
Silibinin potentially protects arsenic-induced oxidative hepatic dysfunction in rats.
Muthumani, M. and S.M. Prabu,
Toxicol. Mechan. Methods,
| Journal Article

S. Milton Prabu
2012
Protective effect of Piper betle leaf extract against cadmium-induced oxidative stress and hepatic dysfunction in rats.
Prabu, S.M., M. Muthumani and K. Shagirtha,
Saudi J. Biol. Sci.,
| Journal Article

S. Milton Prabu
2012
Reno-protective effect of Naringenin in combination with vitamins C and E on cadmium induced oxidative nephrotoxicity in rats.
Prabu, S.M., K. Shagirtha and J. Renugadevi,
J. Pharm. Res.,
| Journal Article

S. Milton Prabu
2011
Quercetin in combination with vitamins (C and E) improve oxidative stress and hepatic injury in cadmium intoxicated rats.
Prabu, S.M., K. Shagirtha and J. Renugadevi,
Biomed. Preventive Nutr.,
| Journal Article

S. Milton Prabu
2011
Naringenin in combination with vitamins C and E potentially protects oxidative stress-mediated hepatic injury in cadmium-intoxicated rats.
Prabu, S.M., K. Shagirtha and J. Renugadevi,
J. Nutr. Sci. Vitaminol.,
| Journal Article

S. Milton Prabu
2011
Melatonin abrogates cadmium induced oxidative stress related neurotoxicity in rats.
Shagirtha, K., M. Muthumani and S.M. Prabu,
Eur. Rev. Med. Pharmacol. Sci.,
| Journal Article

S. Milton Prabu
2011
Cadmium induced hepatotoxicity in rats and the protective effect of naringenin.
Renugadevi, J. and S. Milton Prabu,
Exp. Toxicol. Pathol.,
| Journal Article

S. Milton Prabu
2010
Amelioration of cadmium‐induced oxidative stress, impairment in lipids and plasma lipoproteins by the combined treatment with quercetin and α‐tocopherol in rats.
Prabu, S.M., K. Shagirtha and J. Renugadevi,
J. Food Sci.,
| Journal Article

S. Milton Prabu
2010
Quercetin in combination with vitamins (C and E) improves oxidative stress and renal injury in cadmium intoxicated rats.
Prabu, S.M., K. Shagirtha and J. Renugadevi,
Eur. Rev. Med. Pharmacol. Sci.,
| Journal Article

S. Milton Prabu
2010
Quercetin protects against oxidative stress-related renal dysfunction by cadmium in rats.
Renugadevi, J. and S.M. Prabu,
Exp. Toxicol. Pathol.,
| Journal Article

S. Milton Prabu
2010
A study of the subchronic effects of arsenic exposure on the liver tissues of Labeo rohita using Fourier transform infrared technique.
Palaniappan, P.L., V. Vijayasundaram and S.M. Prabu,
Environ. Toxicol.,
| Journal Article

S. Milton Prabu
2009
Naringenin protects against cadmium-induced oxidative renal dysfunction in rats.
Renugadevi, J. and S.M. Prabu,
Toxicology,
| Journal Article

S. Milton Prabu
2009
Ameliorative effect of quercetin against cadmium induced toxicity in liver of Wistar rats.
Renugadevi, J. and S.M. Prabu,
J. Cell Tissue Res.,
| Journal Article

S. Milton Prabu
2009
Protective role of vitamins C and E against cadmium induced neurotoxicity in rats.
Renugadevi, J., S.M. Prabu and S. Sethupathy,
Int. J. Med. Sci.,
| Journal Article

S. Milton Prabu
2009
Protective role of vitamins C and E against cadmium induced nephrotoxicity in rats.
Renugadevi, J. and S.M. Prabu,
Biochem Cell Arch.,
| Journal Article

S. Milton Prabu
2008
Protective role of vitamins C and E against cadmium induced hepatotoxicity in rats.
Renugadevi, J. and S.M. Prabu,
Asian J. Environ. Sci.,
| Journal Article

S. Milton Prabu
2008
Hepatoprotective effect of Andrographis paniculata against cadmium induced toxicity in male Wistar rats.
Prabu, M.S., N. Selvarajan, S. Hemalatha and T. Rameshkumar,
Toxicol. Int.,
| Journal Article

S. Milton Prabu
2008
Impact of heavy metal mercury on biochemical changes in the adult female Laccotrephes rubber (Linn.) (Heteroptera: Nepidae).
Kumar, T.R. and S.M. Prabu,
Biochem. Cell Arch.,
| Journal Article

S. Milton Prabu
2008
Effect of phytopesticide neem gold on protein metabolism in the fat body, testis, seminal vesicle and MARGs of the adult male Odontopus varicornis (Dist.) (Heteroptera: Pyrrhocoridae).
Kumar, T.R. and S.M. Prabu,
Biochem. Cell Arch.,
| Journal Article

S. Milton Prabu
2008
Protective role of vitamin C and E against cadmium induced nephrotoxicity in rats.
Renugadevi, J. and S.M. Prabu,
Biochem. Cell Arch.,
| Journal Article

S. Milton Prabu
2008
Ameliorative effect of Zinc on Cadmium induced biochemical alterations in Labeo rohita (HAM).
Prabu, S.M., J. Renugadevi and T. Ramesh,
Nat. J. Life Sci.,
| Journal Article

S. Milton Prabu
2007
Effect of phytopesticide neem gold on protein metabolism in the fat body, testis, seminal vesicle and MARGs of the adult male Odontopus varicornis (Dist.)(Heteroptera:Pyrrhocoridae).
Kumar, T.R. and S.M. Prabu,
Indian J. Environ. Ecoplan,
| Journal Article

S. Milton Prabu
2007
Ameliorative effect of curcumin against cadmium induced Hepatotoxocity in rats.
Prabu, S.M. and T.R. Kumar,
Asian J. Environ. Sci.,
| Journal Article

S. Milton Prabu
2007
Attenuative effect of zinc against cadmium induced biochemical alterations in Labeo rohita (Ham).
Prabu, S.M., T. Ramesh and J. Renugadevi,
Indian J. Environ. Toxicol.,
| Journal Article

S. Milton Prabu
2007
Ameliorative effect of selenium on cadmium induced biochemical alterations in Cirrhinus mrigala (Ham.).
Prabu, S.M., J. Renugadevi and T.R. Kumar,
Asian J. Bio Sci.,
| Journal Article

S. Milton Prabu
2007
Impact of phytopesticide nimbecidine in the MARG's of adult male, Odontopus varicornis (Dist.) (Hemiptera: Pyrrhocoridae) in relation to reproduction.
Kowsalya, R., T.R. Kumar, S.M. Prabu and R. Bhagavathiammal,
J. Exp. Zool. India,
| Journal Article

S. Milton Prabu
2007
Impact of heavy metal mercury on protein metabolism in laccotrephes rubber (Linn.) (Heteroptera: Nepidae) in relation to reproduction.
Kumar, T.R. and S.M. Prabu,
Biochem. Cell. Arch.,
| Journal Article

S. Milton Prabu
2007
Antihepatotoxic effect of Vernonia cinerea against cadmium induced toxicity in rats.
Selvarajan, N., S. Hemalatha, T.R. Kumar and S.M. Prabu,
Biochem. Cell Biol.,
| Journal Article

S. Milton Prabu
2007
Effect of zinc on histological changes in the fat body of the adult male Laccotrephes ruber (Lin.) (Heteroptera: Nepidae) in relation to reproduction.
Kumar, T.R. and S.M. Prabhu,
Environ. Ecol.,
| Journal Article

S. Milton Prabu
2006