Dr. Mohammad Husain
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Dr. Mohammad Husain

Professor
Jamia Millia Islamia Central University, India

Highest Degree
PostDoc Fellow in Microbiology and Immunology from University of Arizona, USA

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Area of Interest:

Biomedical Sciences
100%
Physiology
62%
Rotavirus
90%
Virology
75%
Microbiology
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
80
Abstracts
1

Selected Publications

  1. Ganai, A.A. and M. Husain, 2017. Genistein attenuates D-GaIN induced liver fibrosis/chronicliver damage in rats by blocking the TGF-B/Smad signaling pathways. Chem. Biol. Interact., 261: 80-85.
  2. Nafis, S., K. Ponnusamy, M. Husain, R.K.B. Singh and R.N.K. Bamezai, 2016. Identification of key regulators and their controlling mechanism in a combinatorial apoptosis network: a systems biology approach. Mol. Biosyst., 12: 3357-3369.
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  3. Misbah, M., G. Roy, M. Shahid, N. Nag, S. Kumar and M. Husain, 2016. Comparative analysis of drug resistance mutations in the human immunodeficiency virus reverse transcriptase gene in patients who are non-responsive, responsive and naive to antiretroviral therapy. Arch. Virol., 161: 1101-1113.
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  4. Husain, M. and P. Gupta, 2016. Recent advances in HIV/AIDS. In: Holistic Approaches to Infectious Deseases. George, A., K.S. Joshy, M. Sebastian, O.S. Oluwafemi and S. Thomas, (Ed.). Apple Academic Press, USA., pp- 120.147.
  5. Haque, S., X. Lan, H. Wen, R. Lederman and A. Chawla et al., 2016. HIV Promotes NLRP3 Inflammasome Complex Activation in Murine HIV-Associated Nephropathy. Am. J. Pathol., 186: 347-358.
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  6. Ahmad, N., E. Matala, V.R.K. Yedavalli, T. Hahn and M. Husain, 2016. Characterization of human immunodeficiency virus type-1 involved in maternal-fetal transmission. In: Advances in Animal Virology. Jameel, S. and L. Villarreal, (Ed.). Science Inc., USA., pp- 351-370.
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  7. Zaidi, S.L., S. Mittal, M.S. Rajala, F. Avecilla, M. Husain and A. Azam, 2015. Synthesis, characterization and antiamoebic activity of chalcones bearing N-substituted ethanamine tail. Eur. J. Med. Chem., 98: 179-189.
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  8. Nafis, S., P. Kalaiarasan, R.K.B. Singh, M. Husain and R.N.K. Bamezai, 2015. Apoptosis regulatory protein-protein interaction demonstrates hierarchical scale-free fractal network. Briefings Bioinf., 16: 675-699.
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  9. Ayasolla, K.R., P. Rai, S. Rahimipour, M. Husain, A. Malhotra and P.C. Singhal, 2015. Tubular cell phenotype in HIV-associated nephropathy: Role of phospholipid lysophosphatidic acid. Exp. Mol. Pathol., 99: 109-115.
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  10. Gupta, P., M. Husain, C. Hans, H. Ram and S.S. Verma et al., 2014. Sequence heterogeneity in human immunodeficiency virus type 1 nef in patients presenting with rapid progression and delayed progression to AIDS. Arch. Virol., 159: 2303-2320.
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  11. Chandel, N., K. Ayasolla, X. Lan, P. Rai and J. Mikulak et al., 2014. Renin modulates HIV replication in T cells. J. Leukocyte Biol., 96: 601-609.
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  12. Rai, P., A. Plagov, X. Lan, N. Chandel and T. Singh et al., 2013. mTOR plays a critical role in p53-induced oxidative kidney cell injury in HIVAN. Am. J. Physiol. Renal Physiol., 305: 343-354.
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  13. Rai, P., A. Plagov, D. Kumar, S. Pathak and K.R. Ayasolla et al., 2013. Rapamycin-induced modulation of HIV gene transcription attenuates progression of HIVAN. Exp. Mol. Pathol., 94: 255-261.
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  14. Lan, X., P. Rai, N. Chandel, K. Cheng and R. Lederman et al., 2013. Morphine induces albuminuria by compromising podocyte integrity. PLoS One, 10.1371/journal.pone.0055748.
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  15. Lan, X., K. Cheng, N. Chandel, R. Lederman and A. Jhaveri et al., 2013. High glucose enhances HIV entry into T cells through upregulation of CXCR4. J. Leukoc. Biol., 94: 769-777.
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  16. Cheng, K., P. Rai, A. Plagov, X. Lan and P.W. Mathieson et al., 2013. Rapamycin-induced modulation of miRNA expression is associated with amelioration of HIV-associated nephropathy (HIVAN). Exp. Cell Res., 319: 2073-2080.
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  17. Cheng, K., P. Rai, A. Plagov, X. Lan and A. Subrati et al., 2013. MicroRNAs in HIV-associated nephropathy (HIVAN). Exp. Mol. Pathol., 94: 65-72.
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  18. Chandel, N., M. Husain, H. Goel, D. Salhan and X. Lan et al., 2013. VDR hypermethylation and HIV-induced T cell loss. J. Leukoc. Biol., 93: 623-631.
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  19. Chandel, N., B. Sharma, M. Husain, D. Salhan and T. Singh et al., 2013. HIV compromises integrity of the podocyte actin cytoskeleton through downregulation of the vitamin D receptor. Am. J. Physiol. Renal Physiol., 304: 1347-1357.
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  20. Bharadwaj, M., G. Roy, K. Dutta, M. Misbah, M. Husain and S. Hussain, 2013. Tackling hepatitis B virus-associated hepatocellular carcinoma-the future is now. Cancer Metastasis Rev., 32: 229-268.
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  21. Vashistha, H., P.C. Singhal, A. Malhotra, M. Husain and P. Mathieson et al., 2012. Null mutations at the p66 and bradykinin 2 receptor loci induce divergent phenotypes in the diabetic kidney. Am. J. Physiol. Renal Physiol., 303: 1629-1640.
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  22. Singh, P., H. Goel, M. Husain, X. Lan and J. Mikulak et al., 2012. Tubular cell HIV-entry through apoptosed CD4 T cells: A novel pathway. Virology, 434: 68-77.
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  23. Salhan, D., M. Husain, A. Subrati, R. Goyal and T. Singh et al., 2012. HIV- induced kidney cell injury: role of ROS-induced downregulated vitamin D receptor. Am. J. Physiol. Renal Physiol., 303: 503-514.
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  24. Salhan, D., A. Sagar, D. Kumar, R. Rattanavich and P. Rai et al., 2012. HIV-associated nephropathy: Role of AT(2)R. Cell. Signal., 24: 734-741.
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  25. Rehman, S., N. Chandel, D. Salhan, P. Rai and B. Sharma et al., 2012. Ethanol and Vitamin D Receptor in T Cell Apoptosis. J. Neuroimmune Pharmacol., 8: 251-261.
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  26. Rehman, S., M. Husain, A. Yadav, B.S. Kasinath, A. Malhotra and P.C. Singhal, 2012. HIV-1 promotes renal tubular epithelial cell protein synthesis: role of mTOR pathway. PLoS One, 10.1371/journal.pone.0030071.
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  27. Chandel, N., B. Sharma, D. Salhan, M. Husain, A. Malhotra, S. Buch and P.C. Singhal, 2012. Vitamin D receptor activation and downregulation of renin-angiotensin system attenuate morphine- induced T cell apoptosis. Am. J. Physiol. Cell Physiol., 303: 607-615.
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  28. Salhan, D., S. Pathak, M. Husain, P. Tandon and D. Kumar et al., 2011. HIV gene expression deactivates redox-sensitive stress response program in mouse tubular cells both in vitro and in vivo. Am. J. Physiol. Renal Physiol., 302: 129-140.
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  29. Pathak, P., M.C. Sharma, C. Sarkar, P. Jha and V. Suri et al., 2010. Limb girdle muscular dystrophy type 2A in India: a study based on semi-quantitative protein analysis, with clinical and histopathological correlation. Neurol. India, 58: 549-554.
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  30. Vashishtha, H., M. Husain, D. Kumar and P.C. Singhal, 2009. Tubular cell HIV-1 gp120 expression induces caspase 8 activation and apoptosis. Renal Fail., 31: 303-312.
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  31. Husain, M., L.G. Meggs, H. Vashistha, S. Simoes and K.O. Griffiths et al., 2009. Inhibition of p66ShcA Longevity Gene Rescues Podocytes from HIV-1-induced Oxidative Stress and Apoptosis. J. Biol. Chem., 284: 16648-16658.
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  32. Arora, S., M. Husain, H. Patni, L. Luan and F. Batliwala et al., 2009. Human immunodeficiency virus down regulates podocytes ApoE expression. Am. J. Physiol. Renal Physiol., 297: 653-661.
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  33. Vashist, H., M. Husain, D. Kumar, A. Yadav, S. Arora and P.C. Singhal, 2008. HIV-1 expression induces tubular cell G2/M arrest and apoptosis. Renal Fail., 30: 655-664.
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  34. Rosenstiel, P., T.T. Gruosso, A. Letourneau, J. Chan and M. Husain et al., 2008. HIV-1 Vpr inhibits cytokinesis in human proximal tubule cells. Kidney Int., 74: 1049-1058.
  35. He, J.C., T.C. Lu, M. Fleet, M. Sunamoto and M. Husain et al., 2007. Retinoic Acid Inhibits HIV-1-Induced Podocyte Proliferation through the cAMP Pathway. J. Am. Soc. Nephrol., 18: 93-102.
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  36. Zerhouni-Layachi, B., M. Husain, M.J. Ross, D. Marras and M. Sunamoto et al., 2006. Dual tropism of HIV-1 envelopes derived from renal tubular epithelial cells of patients with HIV-associated nephropathy. AIDS, 20: 621-624.
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  37. Ross, M.J., M.S. Wosnitzer, M.D. Ross, B. Granelli and G.L. Gusella et al., 2006. Role of ubiquitin-like protein FAT10 in epithelial apoptosis in renal disease. J. Am. Soc. Nephrol., 17: 996-1006.
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  38. Ramakrishnan, R., M. Husain, A. Holzer, R. Mehta, V. Sundaravaradan and N. Ahmad, 2005. Evaluation of HIV type 1 rev gene diversity and functional domains following perinatal transmission. AIDS Res. Hum. Retroviruses, 21: 1035-1045.
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  39. Husain, M,. V.D. D`Agati, J.C. He, M. Klotman and P.E. Klotman, 2005. HIV-1 Nef induces dedifferentiation of podocytes in vivo: a characteristic feature of HIVAN. AIDS, 19: 1975-1980.
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  40. Yedavalli, V.R.K., M. Husain, A. Horodner and N. Ahmad, 2004. Molecular characterization of HIV type 1 vpu genes from mother and infants after perinatal transmission. AIDS Res. Hum. Retroviruses, 17: 1089-1098.
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  41. Husain, M., T. Hahn, R.K. Yedavalli and N. Ahmad, 2004. Characterization of HIV Type-1 tat sequences associated with perinatal transmission. AIDS Res. Hum. Retroviruses, 17: 765-773.
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  42. He, J.C., M. Husain, M. Sunamoto, V.D. D`Agati, M.E. Klotman, R. Iyengar and P. Klotman, 2004. Nef stimulates proliferation of glomerular podocytes through activation of Src-dependent Stat3 and MAPK1, 2 pathways. J. Clin. Invest., 114: 643-651.
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  43. Sunamoto, M., M. Husain, I.H. Gelman, E.J. Schwartz and P.E. Klotman, 2003. Podocyte dedifferentiation in a mouse model of HIV-associated nephropathy: Role of HIV-1 accessory genes. Kidney Int., 64: 1695-1701.
  44. Nelson, P.J., M. Sunamoto, M. Husain and I.H. Gelman, 2002. HIV-1 expression induces cyclin D1 expression and pRb phosphorylation in infected podocytes: cell cycle mechanisms contributing to the proliferative phenotype in HIV-associated nephropathy. BMC Microbiol., 2: 26-26.
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  45. Husain, M., G.L. Gusella, M.E. Klotman, I.H. Gelman and M.D. Ross et al., 2002. HIV-1 Nef induces proliferation anchorage-independent growth in podocytes. J. Am. Soc. Nephrol., 13: 1806-1815.
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