Dr. Murat  Senturk
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Dr. Murat Senturk

Assistant Professor
Agri Ibrahim Cecen University, Turkiye


Highest Degree
Doctorate in Chemistry from Agri Ibrahim Cecen University, Turkiye

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Biography

Dr. Murat Senturk is currently working as Assistant Professor at Agri Ibrahim Cecen University Science and Art Faculty Department of Chemistry. He has completed his Doctorate in Chemistry from Ataturk University, Graduate School of Natural and Applied Sciences, Department of Chemistry, Biochemistry, Turkey. He has published 55 research articles in journals as well as 19 conference proceeding and 2 book chapters contributed as author/co-author.

Area of Interest:

Chemistry
100%
Organic Chemistry
62%
Enzymes
90%
Chromatographic Techniques
75%
Bioorganic Chemistry
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
0
Abstracts
0

Selected Publications

  1. Sarikaya, S.B.O., A.A. Kaya, E.C. Kaya and M. Senturk, 2015. Synthesis and determination of some biological activities of novel 2,4-dinitrophenyl derivatives. Arch. Pharm., 348: 214-220.
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  2. Korkmaz, N., O.A. Obaidi, M. Senturk, D. Astley, D. Ekinci and C.T. Supuran, 2015. Synthesis and biological activity of novel thiourea derivatives as carbonic anhydrase inhibitors. J. Enzyme Inhibition Med. Chem., 30: 75-80.
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  3. Demirdag, R., V. Comakli, M. Kuzu, E. Yerlikaya and M. Senturk, 2015. Purification and characterization of carbonic anhydrase from Agri Balik Lake Trout Gill (Salmo trutta labrax) and effects of sulfonamides on enzyme activity. J. Biochem. Mol. Toxicol., 29: 123-128.
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  4. Arslan, M., M. Senturk, I. Fidan, O. Talaz, D. Ekinci, S. Cosgun and C.T. Supuran, 2015. Synthesis of 3,4-dihydroxypyrrolidine-2,5-dione and 3,5-dihydroxybenzoic acid derivatives and evaluation of the carbonic anhydrase I and II inhibition. J. Enzyme Inhibition Med. Chem., (In Press). 10.3109/14756366.2014.983917.
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  5. Abdel-Aziz, A.A.M., A.S. El-Azab, D. Ekinci, M. Senturk and C.T. Supuran, 2015. Investigation of arenesulfonyl-2-imidazolidinones as potent carbonic anhydrase inhibitors. J. Enzyme Inhibition Med. Chem., 30: 81-84.
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  6. Atasever, A., M. Arslan, N. Sirkecioglu, A. Bayir, D. Ekinci and M. Senturk, 2014. Influence of different dietary lipids on the activity of metabolic enzymes in brown trout (Salmo trutta). Turk. J. Fish. Aquatic Sci., 14: 31-36.
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  7. Ozdemir, Z.O., M. Senturk and D. Ekinci, 2013. Inhibition of mammalian carbonic anhydrase isoforms I, II and VI with thiamine and thiamine-like molecules. J. Enzyme Inhibit. Med. Chem., 28: 316-319.
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  8. Mercan, L., A. Okumus, M. Senturk and D. Ekinci, 2013. In vitro enzymatic response of Turkish native chicken Gerze to heavy metal exposure. J. Enzyme Inhibit. Med. Chem., 28: 52-57.
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  9. Demirdag, R., E. Yerlikaya, M. Senturk, O.I. Kufrevioglu and C.T. Supuran, 2013. Heavy metal ion inhibition studies of human, sheep and fish α-carbonic anhydrases. J. Enzyme Inhibition Med. Chem., 28: 278-282.
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  10. Senturk, M., H.A. Alici, S. Beydemir and O.I. Kufrevioglu, 2012. In vitro and in vivo effects of some benzodiazepine drugs on human and rabbit erythrocyte carbonic anhydrase enzymes. J. Enzyme Inhibition Med. Chem., 27: 680-684.
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  11. Senturk, M., H. Cavdar, O. Talaz and C.T. Supuran, 2012. Carbonic Anhydrase Inhibitors and Activators: Small Organic Molecules as Drugs and Prodrugs. In: Medicinal Chemistry and Drug Design, Ekinci, D. (Ed.). Chapter 15, InTech Publisher, Rijeka, Croatia, ISBN: 978-953-51-0513-8, pp: 315-328.
  12. Senturk, M., D. Ekinci, S. Goksu and C.T. Supuran, 2012. Effects of dopaminergic compounds on carbonic anhydrase isozymes I, II and VI. J. Enzyme Inhibit. Med. Chem., 27: 365-369.
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  13. Sahin, A., M. Senturk, E. Akkemik and M. Ciftci, 2012. The effects of chemical and radioactive properties of Tl-201 on human erythrocyte glutathione reductase activity. Nuclear Med. Biol., 39: 161-165.
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  14. Kazancioglu, E.A., M. Guney, M. Senturk and C.T. Supuran, 2012. Simple methanesulfonates are hydrolyzed by the sulfatase carbonic anhydrase activity. J. Enzyme Inhibition Med. Chem., 27: 880-885.
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  15. Ekinci, D., N.I. Kurbanoglu, E. Salamci, M. Senturk and C.T. Supuran, 2012. Carbonic anhydrase inhibitors: Inhibition of human and bovine isoenzymes by benzenesulphonamides, cyclitols and phenolic compounds. J. Enzyme Inhibit. Med. Chem., 27: 845-848.
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  16. Ekinci, D., M. Al-Rashida, G. Abbas, M. Senturk and C.T. Supuran, 2012. Chromone containing sulfonamides as potent carbonic anhydrase inhibitors. J. Enzyme Inhibit. Med. Chem., 27: 744-747.
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  17. Ekinci, D., L. Karagoz, D. Ekinci, M. Senturk and C.T. Supuran, 2012. Carbonic anhydrase inhibitors: In vitro inhibition of α isoforms (hCA I, hCA II, bCA III, hCA IV) by flavonoids. J. Enzyme Inhib. Med. Chem., 28: 283-288.
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  18. Ekinci, D., H. Cavdar, S. Durdagi, O. Talaz, M. Senturk and C.T. Supuran, 2012. Structure-activity relationships for the interaction of 5,10-dihydroindeno[1,2-b]indole derivatives with human and bovine carbonic anhydrase isoforms I, II, III, IV and VI. Eur. J. Med. Chem., 49: 68-73.
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  19. Demirdag, R., V. Comaklı, M. Senturk, D. Ekinci, O.I. Kufrevioglu and C.T. Supuran, 2012. Purification and characterization of carbonic anhydrase from sheep kidney and influences of sulfonamides on enzyme activity. Bioorg. Med. Chem., 21: 1522-1525.
    CrossRef  |  PubMed  |  
  20. Cavdar, H., D. Ekinci, O. Talaz, N. Saracoglu, M. Senturk and C.T. Supuran, 2012. α-Carbonic anhydrases are sulfatases with cyclic diol monosulfate esters. J. Enzyme Inhibit. Med. Chem., 27: 148-154.
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  21. Balaydin, H.T., S. Durdagi, D. Ekinci, M. Senturk, S. Goksu and A. Menzek, 2012. Inhibition of human carbonic anhydrase isozymes I, II and VI with a series of bisphenol, methoxy and bromophenol compounds. J. Enzyme Inhibit. Med. Chem., 27: 467-475.
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  22. Balaydin, H.T., M. Senturk and A. Menzek, 2012. Synthesis and carbonic anhydrase inhibitory properties of novel cyclohexanonyl bromophenol derivatives. Bioorg. Med. Chem. Lett., 22: 1352-1357.
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  23. Alp, C., S. Ozsoy, N.A. Alp, D. Erdem and M.S. Gultekin et al., 2012. Sulfapyridine-like benzenesulfonamide derivatives as inhibitors of carbonic anhydrase isoenzymes I, II and VI. J. Enzyme Inhibition Med. Chem., 27: 818-824.
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  24. Senturk, M., I. Gulcin, S. Beydemir, O.I. Kufrevioglu and C.T. Supuran, 2011. In vitro inhibition of human carbonic anhydrase I and II isozymes with natural phenolic compounds. Chem. Biol. Drug Des., 77: 494-499.
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  25. Senturk, M., D. Ekinci, H.A. Alici and S. Beydemir, 2011. Paraoxonase-1, an organophosphate detoxifier and cardioprotective enzyme, is inhibited by anesthetics: An in vitro and in vivo insight. Biochem. Physiol., 101: 206-211.
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  26. Ozturk Sarikaya, S.B., F. Topal, M. Senturk, I. Gulcin and C.T. Supuran, 2011. In vitro inhibition of α-carbonic anhydrase isozymes by some phenolic compounds. Bioorg. Med. Chem. Lett., 21: 4259-4262.
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  27. Ozdemir, Z.O., M. Senturk and D. Ekinci, 2011. Glucose 6-phosphate dehydrogenase activatory properties of some organic compounds and amino acids. Hacettepe J. Biol. Chem., 39: 157-162.
  28. Kuzu, M., M. Senturk and M. Ciftci, 2011. The effect of safranin on glutathione reductase and glucose 6-phosphate dehydrogenase enzymes. Hacettepe J. Biol. Chem., 39: 189-194.
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  29. Erdem, D., E. Yerlikaya, S.B. Ceyhun, M. Senturk, O. Erdogan, R. Demirdag and O.I. Kufrevioglu, 2011. Inhibition effects of some sulfonamides on α-carbonic anhydrase from European seabass (Dicentrachus labrax). Hacettepe J. Biol. Chem., 39: 139-144.
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  30. Ekinci, D., Z.O. Ozdemir and M. Senturk, 2011. Peptide based biological active molecules. Hacettepe J. Biol. Chem., 39: 351-357.
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  31. Ekinci, D., S.B. Ceyhun, M. Senturk, D. Erdem, O.I. Kufrevioglu, and C.T. Supuran, 2011. Characterization and anions inhibition studies of an α-carbonic anhydrase from the teleost fish Dicentrarchus labrax. Bioorg. Med. Chem., 19: 744-748.
    CrossRef  |  
  32. Ekinci, D., M. Senturk and O.I. Kufrevioglu, 2011. Salicylic acid derivatives: Synthesis, features and usage as therapeutic tools. Expert Opin. Therapeut. Patents, 21: 1831-1841.
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  33. Ekinci, D. and M. Senturk, 2011. Assesment of metal inhibition of antioxidant enzyme glutathione reductase from rainbow trout liver. J. Enzyme Inhibit. Med. Chem., 28: 11-15.
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  34. Durdagi, S., M. Senturk, D. Ekinci, H.T. Balaydin and S. Goksu et al., 2011. Kinetic and docking studies of phenol-based inhibitors of carbonic anhydrase isoforms I, II, IX and XII evidence a new binding mode within the enzyme active site. Bioorg. Med. Chem., 19: 1381-1389.
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  35. Ceyhun, S.B., M. Senturk, E. Yerlikaya, O. Erdogan, O.I. Kufrevioglu and D. Ekinci, 2011. Purification and characterization of carbonic anhydrase from the teleost fish Dicentrarchus labrax (European Seabass) liver and toxicological effects of metals on enzyme activity. Environ. Toxicol. Pharmacol., 32: 69-74.
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  36. Cakmak, R., S. Durdagi, D. Ekinci, M. Senturk and G. Topal, 2011. Design, synthesis and biological evaluation of novel nitroaromatic compounds as potent glutathione reductase inhibitors. Bioorg. Med. Chem. Lett., 21: 5398-5402.
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  37. Akkemik, E., M. Senturk, F.B. Ozgeris, P. Taser and M. Ciftci, 2011. In vitro effects of some drugs on human erythrocyte glutathione reductase. Turk. J. Med. Sci., 41: 235-241.
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  38. Sahin, A., M. Senturk, M. Ciftci, E. Varoglu and O.I. Kufrevioglu, 2010. The effects of chemical and radioactive properties of Tl-201 on human erythrocyte glucose 6-phosphate dehydrogenase activity. Nulc. Med. Biol., 37: 389-394.
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  39. Ekinci, D., M. Senturk, S. Beydemir, O.I. Kufrevioglu and C.T. Supuran, 2010. An alternative purification method for human serum paraoxonase 1 and its interactions with sulfonamides. Chem. Biol. Drug Des., 76: 552-558.
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  40. Ekinci, D., M. Senturk, 2010. Interactions of Fungicides and Pesticides with Specific Enzymes. In: Fungicides, Carisse, O. (Ed.). IN-TECH, Rijeka, Croatia, ISBN: 978-953-307-266-1, pp: 383-404.
  41. Ekinci, D., H. Cavdar, O. Talaz, M. Senturk and C.T. Supuran, 2010. NO-releasing esters show carbonic anhydrase inhibitory action against human isoforms I and II. Bioorg. Med. Chem., 18: 3559-3563.
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  42. Ceyhun, S.B., M. Senturk, O. Erdogan and O.I. Kufrevioglu, 2010. In vitro and in vivo effects of some pesticides on carbonic anhydrase enzyme from rainbow trout (Oncorhynchus mykiss) gills. Pestic. Biochem. Physiol., 97: 177-181.
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  43. Ceyhun, S.B., M. Senterk, D. Ekinci, O. Erdogan, A. Ciltas and E.M. Kocaman, 2010. Deltamethrin attenuates antioxidant defense system and induces the expression of heat shock protein 70 in rainbow trout. Comp. Biochem. Physiol. Part C: Toxicol. Pharmacol., 152: 215-223.
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  44. Alp, C., D. Ekinci, M.S. Gultekin, M. Senturk, E. Sahin, O.I. Kufrevioglu, 2010. A novel and one-pot synthesis of new 1-tosyl pyrrol-2-one derivatives and analysis of carbonic anhydrase inhibitory potencies. Bioorg. Med. Chem., 18: 4468-4474.
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  45. Senturk, M., S.B. Ceyhun, O. Erdogan and O.I. Kufrevioglu, 2009. In vitro and in vivo effects of some pesticides on glucose-6-phosphate dehydrogenase enzyme activity from rainbow trout (Oncorhynchus mykiss) erythrocytes. Pestic. Biochem. Phys., 95: 95-99.
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  46. Senturk, M., O.I. Kufrevioglu and M. Ciftci, 2009. Effects of some analgesic anaesthetic drugs on human erythrocyte glutathione reductase: An in vitro study. J. Enzyme Inhibition Med. Chem., 24: 420-424.
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  47. Senturk, M., O. Talaz, D. Ekinci, H. Cavdar and O.I. Kufrevioglu, 2009. In vitro inhibition of human erythrocyte glutathione reductase by some new organic nitrates. Bioorganic Med., Chem. Lett., 19: 3661-3663.
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  48. Senturk, M., I. Gulcin, A. Dastan, O.I. Kufrevioglu and C.T. Supuran, 2009. Carbonic anhydrase inhibitors. Inhibition of human erythrocyte isozymes I and II with a series of antioxidant phenols. Bioorg. Med. Chem., 17: 3207-3211.
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  49. Senturk, M. and O.I. Kufrevioglu, 2009. In vitro effects of some purine analogue drugs on enzyme activities of carbonic anhydrase isozymes I and II from human erythrocytes. Hacettepe J. Biol. Chem., 37: 289-294.
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  50. Tekman, B., H. Ozdemir, M. Senturk and M. Ciftci, 2008. Purification and characterization of glutathione reductase from rainbow trout (Oncorhynchus mykiss) liver and inhibition effects of metal ions on enzyme activity. Comp. Biochem. Physiol. C: Toxicol. Pharmacol., 148: 117-121.
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  51. Senturk, M., O.I. Kufrevioglu and M. Ciftci, 2008. Effects of some antibiotics on human erythrocyte glutathione reductase: An in vitro study. J. Enzyme Inhibition Med. Chem., 23: 144-148.
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  52. Senturk, M., I. Gulcin, M. Ciftci and O.I. Kufrevioglu, 2008. Dantrolene inhibits human erythrocyte glutathione reductase. Biol. Pharmacol. Bull., 31: 2036-2039.
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  53. Bayram, E., M. Senturk, O.I. Kufrevioglu and C.T. Supuran, 2008. In vitro inhibition of salicylic acid derivatives on human cytosolic carbonic anhydrase isozymes I and II. Bioorg. Med. Chem., 16: 9101-9105.
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  54. Coban, T.A., M. Senturk, M. Ciftci and O.I. Kufrevioglu, 2007. Effects of some metal ions on human erythrocyte glutathione reductase: An in vitro study. Protein Peptide Lett., 14: 1027-1030.
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