Dr. Wei-dong  Zhang
My Social Links

Dr. Wei-dong Zhang

Research Director/VP of Research
Second Military Medical University, China


Highest Degree
Ph.D. in Traditional Chinese Medicine from Shanghai Institute of Pharmaceutical Industry, China

Share this Profile

Area of Interest:

Medicine
100%
Biochemistry
62%
Traditional Chinese Medicine
90%
Neural Degenerative Diseases
75%
Metabonomics
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
0
Abstracts
0

Selected Publications

  1. Zhang, Y., L. Shan, Y. Hua, D. Wang and H. Zeng et al., 2013. Baicalein selectively induces apoptosis in activated lymphocytes and ameliorates concanavalin A-induced hepatitis in mice. PloS One, Vol. 8. 10.1371/journal.pone.0069592.
    CrossRef  |  
  2. Yue, R., L. Zhao, Y. Hu, P. Jiang and S. Wang et al., 2013. Rapid-resolution liquid chromatography TOF-MS for urine metabolomic analysis of collagen-induced arthritis in rats and its applications. J. Ethnopharmacol., 145: 465-475.
    CrossRef  |  
  3. Yuan, H., W. Lu, L. Wang, L. Shan, J. Huang and W. Zhang, 2013. Synthesis of derivatives of methyl rosmarinate and their inhibitory activities against matrix metalloproteinase-1 (MMP-1). Eur. J. Med. Chem., 62: 148-157.
    CrossRef  |  Direct Link  |  
  4. Yuan, H., K.J. Bi, B. Li, R.C. Yue and J. Ye et al., 2013. Construction of 2-substituted-3-functionalized benzofurans via intramolecular heck coupling: Application to enantioselective total synthesis of daphnodorin B. Organic Lett., 15: 4742-4745.
    CrossRef  |  Direct Link  |  
  5. Wang, S., L. Wang, P. Jiang, L. Xiang, W. Zhang and R. Liu, 2013. Development and validation of liquid chromatography-tandem mass spectrometry method for simultaneous determination of four tertiary alkaloids in rat plasma and its application to a pharmacokinetic study. J. Pharm. Biochem. Anal., 72: 80-88.
    CrossRef  |  Direct Link  |  
  6. Qu, Y., A.M. Oyan, R. Liu, Y. Hua and J. Zhang et al., 2013. Generation of prostate Tumor-initiating cells is associated with elevation of reactive oxygen species and IL-6/STAT3 signaling. Cancer Res., 73: 7090-7100.
    CrossRef  |  PubMed  |  Direct Link  |  
  7. Liu, X., F. Liu, R. Yue, Y. Li and J. Zhang et al., 2013. The antidepressant-like effect of bacopaside I: Possible involvement of the oxidative stress system and the noradrenergic system. Pharmacol. Biochem. Behav., 110: 224-230.
    CrossRef  |  Direct Link  |  
  8. Liu, S.X., H.Z. Jin, H.W. Zeng, B.Y. Cheng and Q.Y. Sun et al., 2013. Inhibitory effect of 4, 4'-dihydroxy-α-truxillic acid derivatives on NO production in Lipopolysaccharide-induced RAW 264.7 macrophages and exploration of Structure-activity relationships. Bioorganic Med. Chem. Lett., 23: 2207-2211.
    CrossRef  |  Direct Link  |  
  9. Liang, S., S.X. Liu, H.Z. Jin, L. Shan and S.C. Yu et al., 2013. Two novel innovanoside dimers from Daphne aurantiaca and a concise total synthesis of diinnovanoside A. Chem. Commun., 49: 6968-6970.
    CrossRef  |  
  10. Li, X., X. Yang, Y. Liu, N. Gong and W. Yao et al., 2013. Japonicone a suppresses growth of burkitt lymphoma cells through its effect on NF-κB. Clin. Cancer Res., 19: 2917-2928.
  11. Li, X., T. Chen, S. Lin, J. Zhao and P. Chen et al., 2013. Valeriana jatamansi constituent IVHD-valtrate as a novel therapeutic agent to human ovarian cancer: In vitro and in vivo activities and mechanisms. Curr. Cancer Drug Targets, 13: 472-483.
    Direct Link  |  
  12. Li, C., T. Dong, L. Dian, W. Zhang and X. Lei, 2013. Biomimetic syntheses and structural elucidation of the apoptosis-inducing sesquiterpenoid trimers:(-)-ainsliatrimers A and B. Chem. Sci., 4: 1163-1167.
    CrossRef  |  
  13. Li, B., D.Y. Kong, Y.H. Shen, K.L. Fu and R.C. Yue et al., 2013. Pseudolarenone, an unusual nortriterpenoid lactone with a fused 5/11/5/6/5 ring system featuring an unprecedented bicyclo[8.2.1]tridecane core from Pseudolarix amabilis. Chem. Commun., 49: 1187-1189.
    CrossRef  |  
  14. Fu, P., R.L. Zhu, R.H. Liu, H.L. Li and W.L. Yuan et al., 2013. A new sesquiterpene coupled with phenolic units and a new shikimic acid derivative from the Malaysia liverwort Conoscyphus Trapezioides. Biochem. Syst. Ecol., 46: 69-72.
    CrossRef  |  Direct Link  |  
  15. Zhu, J.X., J.J. Qin, R.J. Chang, Q. Zeng, X.R. Cheng, F. Zhang, H.Z. Jin and W.D. Zhang, 2012. Chemical constituents of plants from the genus Euonymus. Chem. Biodiversity, 9: 1055-1076.
    CrossRef  |  
  16. Zhao, J., P. Yang, F. Li, L. Tao and H. Ding et al., 2012. Therapeutic effects of astragaloside IV on myocardial injuries: Multi-target identification and network analysis. PLoS One, Vol. 7. 10.1371/journal.pone.0044938.
    CrossRef  |  
  17. Zhang, Y., S. Yan, X. Gao, X. Xiong and W. Dai et al., 2012. Analysis of urinary metabolic profile in aging rats undergoing caloric restriction. Aging Clin. Exp. Res., 24: 79-84.
    PubMed  |  
  18. Zhang, S.D., J.J. Qin, H.Z. Jin, Y.H. Yin and H.L. Li et al., 2012. Sesquiterpenoids from Inula racemosa Hook. f. inhibit nitric oxide production. Planta Med., 78: 166-171.
    CrossRef  |  Direct Link  |  
  19. Zhang, J., W. Cao, J. Tian, R. Yue and L. Li et al., 2012. Evaluation of novel saponins from Psammosilene tunicoides and their analogs as immunomodulators. Int. Immunopharmacol., 14: 21-26.
    PubMed  |  
  20. Zeng, Q., B. Guan, J.J. Qin, C.H. Wang and X.R. Cheng et al., 2012. 2, 3-Seco-and 3, 4-seco-tirucallane triterpenoid derivatives from the stems of Aphanamixis grandifolia Blume. Phytochemistry, 80: 148-155.
    CrossRef  |  Direct Link  |  
  21. Yue, R., X. Yuan, X. Liu, J. Zhang and P. Jiang et al., 2012. Cynandione A mitigates ischemic injuries in rats with cerebral ischemia. J. Neurochem., 121: 451-464.
    CrossRef  |  Direct Link  |  
  22. Yue, R., L. Shan, X. Yang and W. Zhang, 2012. Approaches to target profiling of natural products. Curr. Med. Chem., 19: 3841-3855.
    CrossRef  |  Direct Link  |  
  23. Yu, P., S.D. Zhang, Y.L. Li, X.W. Yang, H.W. Zeng, H.L. Li and W.D. Zhang, 2012. Abieseconordines A and B, two novel norditerpenoids with a 18-Nor-5,10 : 9,10-disecoabietane skeleton from Abies forrestii. Helvetica Chim. Acta, 95: 415-422.
    CrossRef  |  
  24. Yang, X., J. Su, Y. He, H. Liu, H. Li and W. Zhang, 2012. Simultaneous determination of three sesquiterpene lactones from Herba inula extract in rat plasma by LC/MS/MS and its application to pharmacokinetic study. J. Chromatography B, 903: 40-45.
    CrossRef  |  Direct Link  |  
  25. Yang, W., J. Sun, Z. Yang, W. Han, W.D. Zhang and B. Yu, 2012. Efficient synthesis of kaempferol 3, 7-O-bisglycosides via successive glycosylation with glycosyl ortho-alkynylbenzoates and trifluoroacetimidates. Tetrahedron Lett., 53: 2773-2776.
  26. Xiao, L., D. Guo, C. Hu, W. Shen and L. Shan et al., 2012. Diosgenin promotes oligodendrocyte progenitor cell differentiation through estrogen receptor-mediated ERK1/2 activation to accelerate remyelination. Glia, 60: 1037-1052.
    CrossRef  |  
  27. Xiang, L., P. Jiang, C. Zhan, Z. Chen and X. Liu et al., 2012. The serum metabolomic study of intervention effects of the traditional Chinese medicine Shexiang Baoxin Pill and a Multi-component medicine polypill in the treatment of myocardial infarction in rats. Mol. BioSyst., 8: 2434-2442.
    CrossRef  |  Direct Link  |  
  28. Xia, J.H., Y.L. Li, S.M. Li, Z.J. Zhu and L. Wu et al., 2012. Two new compounds from Abies holophylla. Phytochem. Lett., 5: 446-449.
    CrossRef  |  Direct Link  |  
  29. Xia, J.H., S.D. Zhang, Y.L. Li, L. Wu, Z.J. Zhu, X.W. Yang and W.D. Zhang, 2012. Sesquiterpenoids and triterpenoids from Abies holophylla and their bioactivities. Phytochemistry, 74: 178-184.
    CrossRef  |  Direct Link  |  
  30. Wang, S., L. Liu, L. Wang, Y. Hu, J. Zhang, W. Zhang and R. Liu, 2012. Structural characterization and identification of major constituents in Jitai tablets by high-performance liquid chromatography/diode-array detection coupled with electrospray ionization tandem mass spectrometry. Molecules, 17: 10470-10493.
    CrossRef  |  
  31. Wang, L., X. Li, S. Zhang, W. Lu and S. Liao et al., 2012. Natural products as a gold mine for selective matrix metalloproteinases inhibitors. Bioorg. Med. Chem., 20: 4164-4171.
    PubMed  |  
  32. Wang, G.R., Y.L. Li, W.D. Zhang, X.W. Yang and W.C. Liu et al., 2012. Cytotoxic terpenes from Abies sibirica. Chinese Chem. Lett., 23: 1251-1253.
    CrossRef  |  Direct Link  |  
  33. Tian, J.M., S.S. Ou-Yang, X. Zhang, Y.T. Di and H.L. Jiang et al., 2012. Experimental and computational insights into the conformations of tunicyclin E, a new cycloheptapeptide from Psammosilene tunicoides. RSC Adv., 2: 1126-1135.
    CrossRef  |  Direct Link  |  
  34. Tian, J.M., J.M. Gao, L. Lu, Y.R. He and Y.H. Shen et al., 2012. Two new cycloheptapeptides from Psammosilene tunicoides. HCA, 95: 929-934.
    CrossRef  |  Direct Link  |  
  35. Tian, J., Y. Shen, H. Li, R. Liu, L. Shan, J. Gao and W. Zhang, 2012. Carboline alkaloids from Psammosilene tunicoides and their cytotoxic activities. Planta Med., 78: 625-629.
    CrossRef  |  Direct Link  |  
  36. Tan, Y., J. Li, X. Liu, J. Ko and X. He et al., 2012. Deciphering the differential toxic responses of Radix aconiti lateralis praeparata in healthy and Hydrocortisone-pretreated rats based on serum metabolic profiles. J. Proteome Res., 12: 513-524.
    CrossRef  |  Direct Link  |  
  37. Shen, Y.H., Y. Ding, T. Lu, X.C. Li and J.M. Tian et al., 2012. Incarviatone A, a structurally unique natural product hybrid with a new carbon skeleton from Incarvillea delavayi and its absolute configuration via calculated electronic circular dichroic spectra. RSC Adv., 2: 4175-4180.
    CrossRef  |  Direct Link  |  
  38. Qin, J.J., Y. Huang, D. Wang, X.R. Cheng and Q. Zeng et al., 2012. Lineariifolianoids A-D, rare unsymmetrical sesquiterpenoid dimers comprised of xanthane and guaiane framework units from Inula lineariifolia. RSC Adv., 2: 1307-1309.
    CrossRef  |  Direct Link  |  
  39. Qin, J.J., J.X. Zhu, Q. Zeng, X.R. Cheng, S.D. Zhang, H.Z. Jin and W.D. Zhang, 2012. Sesquiterpene lactones from Inula hupehensis inhibit nitric oxide production in RAW264. 7 macrophages. Planta Med., 78: 1002-1009.
    CrossRef  |  Direct Link  |  
  40. Lu, Y., Y. Zheng, X. Liu, X. Liang and S. Ngai et al., 2012. Metabolomic profiles of myocardial ischemia under treatment with salvianolic acid B. Chinese Med., Vol. 7 10.1186/1749-8546-7-6.
    CrossRef  |  
  41. Liu, Y., S. Yan, C. Ji, W. Dai and Z. Lin et al., 2012. Metabolomic changes and protective effect of L-carnitine in rat kidney ischemia/reperfusion injury. Kidney Blood Pressure Res., 35: 373-381.
    CrossRef  |  Direct Link  |  
  42. Lin, S., Z.X. Zhang, T. Chen, J. Ye and W.X. Dai et al., 2012. Characterization of chlorinated valepotriates from Valeriana jatamansi. Phytochemistry, 85: 185-193.
    CrossRef  |  Direct Link  |  
  43. Li, Y.L., Y.X. Gao, Z.J. Zhu, X.W. Yang and H.Z. Jin et al., 2012. Cytotoxic triterpenoids from Abies recurvata. Phytochemistry, 81: 159-164.
    CrossRef  |  Direct Link  |  
  44. Li, Y.L., S.D. Zhang, H.Z. Jin, J.M. Tian, X.W. Yang, H.L. Li and W.D. Zhang, 2012. Abiestetranes A and B, two unique triterpene from Abies fabric. Tetrahedron, 68: 7763-7767.
  45. Li, Y.L., J.G. Zhang, B.L. Ke, P. Yu and J. Ye et al., 2012. New Mono-and diterpenoids, lignans and other compounds from Abies recurvata. Planta Med., 78: 1574-1578.
  46. Li, L., H.W. Zeng, F. Liu, J.G. Zhang and R.C. Yue et al., 2012. Target identification and validation of (+)-2-(1-hydroxyl-4-oxocyclohexyl) ethyl caffeate, an anti-inflammatory natural product. Eur. J. Inflammation, 10: 297-309.
    Direct Link  |  
  47. Li, L., H. Zeng, L. Shan, X. Yuan, Y. Li, R. Liu and W. Zhang, 2012. The different inhibitory effects of Huang-Lian-Jie-Du-Tang on cyclooxygenase 2 and 5-lipoxygenase. J. Ethnopharm., 143: 732-739.
    CrossRef  |  
  48. Li, C., L. Dian, W. Zhang and X. Lei, 2012. Biomimetic syntheses of (-)-Gochnatiolides A-C and (-)-Ainsliadimer B. J. Am. Chem. Soc., 134: 12414-12417.
    CrossRef  |  Direct Link  |  
  49. Li, B., Y.H. Shen, C.X. Li, Y.R. He and W.D. Zhang, 2012. Terpenoids from Pinus densata Mast. and their chemotaxonomic significance. Biochem. Systematics Ecol., 44: 79-82.
  50. Li, B., W.D. Zhang, Y.R. He, L. Lu, D.Y. Kong and Y.H. Shen, 2012. New alkaloids from Lycopodium japonicum. Chem. Pharm. Bull., 60: 1448-1452.
  51. Li, B., D.Y. Kong, Y.H. Shen, H. Yuan and R.C. Yue et al., 2012. Pseudolaridimers A and B, the first two hetero cycloartanelabdane dimers from the cone of Pseudolarix kaempferi. Organic Lett., 14: 5432-5435.
  52. Hu, Z., Y. Hua, H. Zhang,D. Wang and J. Qin, 2012. Japonicone A, a Plant-derived compound, antagonizes the activity of TNF-a by directly targeting this cytokine and selectively disrupting its interaction with TNF receptor-1. Biochem. Pharmacol., 84: 1482-1491.
  53. Hu, Y., P. Jiang, S. Wang, S. Yan, L. Xiang, W. Zhang and R. Liu, 2012. Plasma pharmacochemistry based approach to screening potential bioactive components in Huang-Lian-Jie-Du-Tang using high performance liquid chromatography coupled with mass spectrometric detection. J. Ethnopharmacol., 141: 728-735.
    PubMed  |  
  54. Han, Z.Z., Z.H. Yan, Q.X. Liu, X.Q. Hu, J. Ye, H.L. Li and W.D. Zhang, 2012. Acylated iridoids from the roots of Valeriana officinalis var. latifolia. Planta Med., 78: 1645-1650.
    CrossRef  |  Direct Link  |  
  55. Gao, Y.P., Y.H. Shen, S. de Zhang, J.M. Tian and H.W. Zeng et al., 2012. Incarvilleatone, a unique benzofurantone dimer from Incarvillea younghusbandii and its inhibition against Nitric Oxide (NO) release. Organic Lett., 14: 1954-1957.
  56. Fu, J.J., L.Y. Wang, H.L. Li, J.J. Qin and Y.H. Shen et al., 2012. Argutalactone, an unprecedented sesquiterpenoid lactone with a 6/5/7 tricyclic system from Incarvillea arguta. J. Asian Nat. Prod. Res., 14: 496-502.
    CrossRef  |  Direct Link  |  
  57. Fan, S.Y., H.W. Zeng, Y.H. Pei, L. Li and J. Yeet al., 2012. The anti-inflammatory activities of an extract and compounds isolated from Platycladus orientalis (Linnaeus) Franco in vitro and ex vivo. J. Ethnopharmacol., 141: 647-652.
    PubMed  |  
  58. Cheng, X.R., W.W. Li, J. Ren, Q. Zeng and S.D. Zhang et al., 2012. Sesquiterpene lactones from Inula hookeri. Planta Med., 78: 465-471.
    CrossRef  |  Direct Link  |  
  59. Cheng, X.R., J. Ye, J. Ren, Q. Zeng and F. Zhang et al., 2012. Terpenoids from Inula sericophylla Franch. and their chemotaxonomic significance. Biochem. Syst. Ecol., 42: 75-78.
  60. Chen, K., J. Ye, C. Liu, P. Di and J. Chen et al., 2012. Molecular characterization, recombinant expression in Escherichia coli and biological activity of (S)-Tetrahydroberberine oxidase from Corydalis saxicola Bunt. Mol. Biol. Rep., 39: 3319-3326.
    CrossRef  |  Direct Link  |  
  61. Zhu, S.L., S.S. Dou, X.R. Liu, R.H. Liu and W.D. Zhang et al., 2011. Qualitative and quantitative analysis of alkaloids in Cortex Phellodendri by HPLC-ESI-MS/MS and HPLC-DAD. Chem. Res. Chinese Univ., 27: 38-44.
    Direct Link  |  
  62. Zhu, R., L. Hu, H. Li, J. Su, Z. Cao and W. Zhang, 2011. Novel natural inhibitors of CYP1A2 identified by in silico and in vitro screening. Int. J. Mol. Sci., 12: 3250-3262.
    CrossRef  |  
  63. Zhu, J.X., J.J. Qin, H.R. Wang, Y. Zhu, W.D. Zhang and H.Z. Jin, 2011. Monoterpenes and other chemical constituents from the aerial parts of Inula japonica. Chem. Nat. Compounds, 47: 303-305.
  64. Zhang, Y., H. Jin, J. Qin, J. Fu, X. Cheng and W. Zhang, 2011. Chemical constituents from Verbena officinalis. Chem. Nat. Compounds, 47: 319-320.
    CrossRef  |  
  65. Zhang, S., W. Lu, X. Liu, Y. Diao and F. Bai et al., 2011. Fast and effective identification of the bioactive compounds and their targets from medicinal plants via computational chemical biology approach. MedChemComm, 2: 471-477.
    CrossRef  |  Direct Link  |  
  66. Zeng, Q., R. Chang, J. Qin, X. Cheng, W. Zhang and H. Jin, 2011. New glycosides from Dracocephalum tanguticum maxim. Arch. Pharm. Res., 34: 2299-2309.
  67. Zeng, H., S. Dou, J. Zhao, S. Fan and X. Yuan et al., 2011. The inhibitory activities of the components of Huang-Lian-Jie-Du-Tang (HLJDT) on eicosanoid generation via lipoxygenase pathway. J. Ethnopharmacol., 135: 561-568.
    PubMed  |  
  68. Yuan, X., S. Yan, J. Zhao, D. Shi and B. Yuan et al., 2011. Lipid metabolism and peroxisome Proliferator-activated receptor signaling pathways participate in Late-phase liver regeneration. J. Proteome Res., 10: 1179-1190.
    CrossRef  |  Direct Link  |  
  69. Yang, X.W., Y.L. Li, S.M. Li, Y.H. Shen and J.M. Tian et al., 2011. Mono-and sesquiterpenoids, flavonoids, lignans and other miscellaneous compounds of Abies georgei. Planta Med., 77: 742-748.
    PubMed  |  
  70. Yang, X.W., X.Q. Chen, G. Dong, X.F. Zhou and X.Y. Chai et al., 2011. Isolation and structural characterisation of five new and 14 known metabolites from the commercial starfish Archaster typicus. Food Chem., 124: 1634-1638.
    Direct Link  |  
  71. Yang, W., W. Han, W. Zhang, L. Shan and J. Sun, 2011. Efficient carbonylation of aryl and heteroaryl bromides under atmospheric pressure of CO. Synlett, 15: 2253-2255.
    CrossRef  |  
  72. Yan, L., X.R. Cheng, Q. Zeng, J.J. Qin, W.D. Zhang and H.Z. Jin, 2011. Phytane and neoclerodane diterpenes from the aerial parts of Inula nervosa Wall. Biochem. Syst. Ecol., 39: 700-703.
  73. Wu, Z.J., X.K. Xu, H.W. Zeng, Y.H. Shen and J.M. Tian et al., 2011. New sesquiterpenoids from Ainsliaea macrocephala and their nitric oxide inhibitory activity. Planta Med., 77: 1545-1550.
    CrossRef  |  
  74. Qin, J.J., L.Y. Wang, J.X. Zhu, H.Z. Jin and J.J. Fu et al., 2011. Neojaponicone A, a bioactive sesquiterpene lactone dimer with an unprecedented carbon skeleton from Inula japonica. Chem. Commun., 47: 1222-1224.
    CrossRef  |  Direct Link  |  
  75. Qin, J.J., J.X. Zhu, Q. Zeng, X.R. Cheng and Y. Zhu et al., 2011. Pseudoguaianolides and guaianolides from Inula hupehensis as potential Anti-inflammatory agents. J. Nat. Prod., 74: 1881-1887.
    CrossRef  |  Direct Link  |  
  76. Ou-Yang, D.W., L. Wu, Y.L. Li, P.M. Yang, D.Y. Kong, X.W. Yang and W.D. Zhang, 2011. Miscellaneous terpenoid constituents of Abiesnephrolepis and their moderate cytotoxic activities. Phytochemistry, 72: 2197-2204.
    CrossRef  |  Direct Link  |  
  77. Lv, Y., X. Liu, X. Liang, L. Xiang and W. Zhang, 2011. Metabolomic strategy to study therapeutic and synergistic effects of tanshinone IIA, salvianolic acid B and ginsenoside Rb1 in myocardial ischemia rats. J. Enthopharmacol., 134: 45-49.
    PubMed  |  
  78. Liu, Y.B., J.J. Qin, X.R. Cheng, J.X. Zhu, F. Zhang, H.Z. Jin and W.D. Zhang, 2011. Three new neolignans and one new phenylpropanoid from the leaves and stems of Toona ciliate var. pubescens. Helvetica Chim. Acta, 94: 1685-1691.
    CrossRef  |  
  79. Lin, S., T. Shi, K.Y. Chen, Z.X. Zhang, L. Shan, Y.H. Shen and W.D. Zhang, 2011. Cyclopenicillone, a unique cyclopentenone from the cultures of Penicillium decumbens. Chem. Commun., 47: 10413-10415.
    CrossRef  |  Direct Link  |  
  80. Liang, S., Z. Xiong, J. Tian and W.D. Zhang, 2011. Flavones from Daphne feddei. Chem. Nat. Compounds, 47: 816-817.
    CrossRef  |  Direct Link  |  
  81. Liang, S., Y.H. Shen, J.M. Tian, Y. Feng, Z. Xiong and W.D. Zhang, 2011. Five new biflavonoids from Daphne aurantiaca. Helvetica Chim. Acta, 94: 1239-1245.
    CrossRef  |  
  82. Liang, S., J.M. Tian, Y. Feng, X.H. Liu, Z. Xiong and W.D. Zhang, 2011. Flavonoids from Daphne aurantiaca and their inhibitory activities against nitric oxide production. Chem. Pharm. Bull., 59: 653-656.
    CrossRef  |  PubMed  |  
  83. Li, Y.L., L. Wu, D.W. Ouyang, P. Yu and J.H. Xia et al., 2011. Phenolic compounds of Abies nephrolepis and their NO production inhibitory activities. Chem. Biodiversity, 8: 2299-2309.
    CrossRef  |  
  84. Jiang, P., W. Dai, S. Yan, Z. Chen and R. Xu et al., 2011. Potential biomarkers in the urine of myocardial infarction rats: A metabolomic method and its application. Mol. BioSyst., 7: 824-831.
    CrossRef  |  Direct Link  |  
  85. Jiang, P., W. Dai, S. Yan, Z. Chen and R. Xu et al., 2011. Biomarkers in the early period of acute myocardial infarction in rat serum and protective effects of Shexiang Baoxin Pill using a metabolomic method. J. Ethnopharmacol., 138: 530-536.
    PubMed  |  
  86. Huang, Y., Q. Zeng, J.J. Fu, Z.J. Kou, R.J. Chang, H.Z. Jin and W.D. Zhang, 2011. Chemical constituents from Tsoongiodendron odorum Chun. Biochem. Syst. Ecol., 39: 209-212.
  87. Huang, H.Q., J. Su, X. Zhang, L. Shan and W.D. Zhang, 2011. Qualitative and quantitative determination of polyacetylenes in different< i> Bupleurum species by high performance liquid chromatography with diode array detector and mass spectrometry. J. Chromatography A, 1218: 1131-1138.
    CrossRef  |  Direct Link  |  
  88. Hu, Z., Q. Jiao, J. Ding, F. Liu, R. Liu et al., 2011. Berberine induces dendritic cell apoptosis and has therapeutic potential for rheumatoid arthritis. Arthritis Rheumatism, 63: 949-959.
  89. Hu, X.J., H.Z. Jin, X.H. Liu and W.D. Zhang, 2011. Two new sesquiterpenes from Inula salsoloides and their inhibitory activities against NO production. Helvetica Chim. Acta, 94: 306-312.
    CrossRef  |  
  90. Fu, J.J., J.J. Qin, Q. Zeng, Y. Huang, W.D. Zhang and H.Z. Jin, 2011. Two new monoterpene alkaloid derivatives from the roots of Incarvillea arguta. Arch. Pharmacal Res., 34: 199-202.
    CrossRef  |  Direct Link  |  
  91. Fan, S.Y., Y.H. Pei, H.W. Zeng, S.D. Zhang and Y.L. Li et al., 2011. Compounds from Platycladus orientalis and their inhibitory effects on nitric oxide and TNF-α production. Planta Med., 77: 1623-1630.
    CrossRef  |  Direct Link  |  
  92. Cheng, X.R., H.Z. Jin, J.J. Qin, J.J. Fu and W.D. Zhang, 2011. Chemical constituents of plants from the genus Geum. Chem. Biodiversity, 8: 203-222.
    CrossRef  |  
  93. Cheng, X., Q. Zeng, J. Ren, J. Qin and S. Zhang et al., 2011. Sesquiterpene lactones from Inula falconeri, a plant endemic to the Himalayas, as potential Anti-inflammatory agents. Eur. J. Med. Chem., 46: 5408-5415.
    CrossRef  |  Direct Link  |  
  94. Cheng, X., J. Qin, Q. Zeng, S. Zhang and F. Zhang et al., 2011. Taraxasterane-type triterpene and neolignans from Geum japonicum Thunb. var. chinense F. Bolle. Planta Med., 77: 2061-2065.
    CrossRef  |  
  95. Zhu, X., X. Liu, P. He, B. Cao, Y. Lv, W. Zhang and X. Ni, 2010. Metabolomics in serum of ovariectomised rats and those exposed to 17β-oestradiol and genistein. Gynecol. Endocrinol., 26: 760-767.
    CrossRef  |  Direct Link  |  
  96. Zhao, J., P. Jiang and W. Zhang, 2010. Molecular networks for the study of TCM pharmacology. Briefings Bioinform., 11: 417-430.
    CrossRef  |  
  97. Zhao, J., C. Geng, L. Tao, D. Zhang and Y. Jiang et al., 2010. Reconstruction and analysis of human Liver-specific metabolic network based on CNHLPP data. J. Proteome Res., 9: 1648-1658.
    CrossRef  |  Direct Link  |  
  98. Zeng, Q., H.Z. Jin, J.J. Qin, J.J. Fu and X.J. Hu et al., 2010. Chemical constituents of plants from the genus Dracocephalum. Chem. Biodiversity, 7: 1911-1929.
    CrossRef  |  Direct Link  |  
  99. Yang, X.W., Y.L. Li, S.M. Li, L. Feng and Y.H. Shen et al., 2010. Isolation, structure and bioactivities of abiesadines A-Y, 25 new diterpenes from Abies georgei Orr. Bioorganic Med. Chem., 18: 744-754.
    PubMed  |  
  100. Yang, X.W., S.M. Li, L. Wu, Y.L. Li and L. Feng et al., 2010. Abiesatrines A-J: Anti-inflammatory and antitumor triterpenoids from Abies georgei Orr. Organic Biomol. Chem., 8: 2609-2616.
    CrossRef  |  Direct Link  |  
  101. Yan, L., Y. Huang, J.J. Fu, J.J. Qin and Q. Zeng et al., 2010. Three new phenylpropanoids from Inula nervosaWall. HCA, 93: 1418-1421.
    CrossRef  |  
  102. Xing, A.T., J.M. Tian, C.M. Liu, H.L. Li, W.D. Zhang and L. Shan, 2010. Three new monoterpene alkaloids and a new caffeic acid ester from Incarvillea mairei var. multifoliolata. HCA, 93: 718-723.
    CrossRef  |  
  103. Xia, X., H. Jin, S. Yan and W. Zhang, 2010. Analysis of the bioactive constituents of ChanSu in rat plasma by high performance liquid chromatography with mass spectrometric detection. J. Pharm. Biomed. Anal., 53: 646-654.
    CrossRef  |  Direct Link  |  
  104. Wu, Z.J., L. Shan, M. Lu, Y.H. Shen, J. Tang and W.D. Zhang, 2010. Chemical constituents from Inula cappa. Chem. Nat. Compounds, 46: 298-300.
    CrossRef  |  Direct Link  |  
  105. Wu, L., Y.L. Li, S.M. Li, X.W. Yang, J.H. Xia, L. Zhou and W.D. Zhang, 2010. Systematic phytochemical investigation of Abies spectabilis. Chem. Pharm. Bull., 58: 1646-1649.
    CrossRef  |  Direct Link  |  
  106. Wang, S.P., L. Liu, L.L. Wang, P. Jiang, J.Q. Zhang, W.D. Zhang and R.H. Liu, 2010. Screening and analysis of the multiple absorbed bioactive components and metabolites in rat plasma after oral administration of Jitai tablets by High-performance liquid chromatography/diode-array detection coupled with electrospray ionization tandem mass spectrometry. Rapid Commun. Mass Spectrometry, 24: 1641-1652.
    CrossRef  |  Direct Link  |  
  107. Tang, J., H.L. Li, Y.H. Shen, H.Z. Jin and S.K. Yan et al., 2010. Antitumor and antiplatelet activity of alkaloids from veratrum dahuricum. Phytother. Res., 24: 821-826.
    CrossRef  |  Direct Link  |  
  108. Su, Y.Q., Y.H. Shen, J. Tang and W.D. Zhang, 2010. Chemical constituents of Incarvillea mairei var. grandiflora. Chem. Nat. Compounds, 46: 109-111.
    CrossRef  |  Direct Link  |  
  109. Shen, Y.H., T. Lu, J. Tang, R.H. Liu, H.L. Li and W.D. Zhang, 2010. Chemical constituents from Incarvillea delavayi. Chem. Nat. Compounds, 46: 305-307.
    CrossRef  |  Direct Link  |  
  110. Qin, J.J., H.Z. Jin, J.X. Zhu, J.J. Fu and X.J. Hu et al., 2010. Japonicones E-L, dimeric sesquiterpene lactones from Inula japonica Thunb. Planta Medica, 76: 278-283.
    CrossRef  |  Direct Link  |  
  111. Qin, J.J., H.Z. Jin, J.J. Fu, X.J. Hu, Y. Wang, S.K. Yan and W.D. Zhang, 2010. Corrigendum to Japonicones A-D, bioactive dimeric sesquiterpenes from Inula japonica Thunb. [Bioorg. Med. Chem. Lett. 19 (2009) 710-713]. Bioorg. Med. Chem. Lett., 20: 5584-5584.
    CrossRef  |  
  112. Nie, L.Y., J.J. Qin, Y. Huang, L. Yan and Y.B. Liu et al., 2010. Sesquiterpenoids from Inula lineariifolia inhibit nitric oxide production. J. Nat. Prod., 73: 1117-1120.
    CrossRef  |  Direct Link  |  
  113. Lv, Y., X. Zhang, X. Liang, X. Liu, W. Dai, S. Yan and W. Zhang, 2010. Characterization of the constituents in rat biological fluids after oral administration of Fufang Danshen tablets by ultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometry. J. Pharm. Biochem. Anal., 52: 155-159.
    CrossRef  |  PubMed  |  
  114. Lv, Y., X. Liu, S. Yan, X. Liang, Y. Yang, W. Dai and W. Zhang, 2010. Metabolomic study of myocardial ischemia and intervention effects of Compound Danshen Tablets in rats using Ultra-performance liquid chromatography/quadrupole Time-of-flight mass spectrometry. J. Pharm. Biomed. Anal., 52: 129-135.
    PubMed  |  
  115. Liu, X.R., X.F. Zheng, S.Z. Ji, Y.H. Lv, D.Y. Zheng, Z.F. Xia and W.D. Zhang, 2010. Metabolomic analysis of thermally injured and/or septic rats. Burns, 36: 992-998.
    CrossRef  |  PubMed  |  
  116. Liu, X., Z. Hu, Q. Shi, H. Zeng, Y. Shen, H. Jin and W. Zhang, 2010. Anti-inflammatory and Anti-nociceptive activities of compounds from Tinospora sagittata (Oliv.) Gagnep. Arch. Pharm. Res., 33: 981-987.
    CrossRef  |  Direct Link  |  
  117. Liu, X., W. Liu, X. Sun, K. Liu, W. Xu and W. Zhang, 2010. Effects of hyperbaric oxygen on uric acid and arachidonic acid: A metabolomic study in rats and humans. Metabolomics, 6: 375-385.
    CrossRef  |  Direct Link  |  
  118. Liu, C.M., B. Li, Y.H. Shenand W.D. Zhang, 2010. Heterocyclic compounds and aromatic diglycosides from Bretschneidera sinensis. J. Nat. Prod., 73: 1582-1585.
    CrossRef  |  Direct Link  |  
  119. Lin, S., T. Chen, X.H. Liu, Y.H. Shen and H.L. Li et al., 2010. Iridoids and lignans from Valeriana jatamansi. J. Nat. Prod., 73: 632-638.
    CrossRef  |  Direct Link  |  
  120. Liang, X., L. Zhang, X. Zhang, W. Dai and H. Li et al., 2010. Qualitative and quantitative analysis of traditional Chinese medicine Niu Huang Jie Du Pill using ultra performance liquid chromatography coupled with tunable UV detector and rapid resolution liquid chromatography coupled with time-of-flight tandem mass spectrometry. J. Pharm. Biochem. Anal., 51: 565-571.
    PubMed  |  
  121. Liang, S., Y.H. Shen, Y. Feng, J.M. Tian, X.H. Liu, Z. Xiong and W.D. Zhang, 2010. Terpenoids from Daphne aurantiaca and their potential Anti-inflammatory activity. J. Nat. Prod., 73: 532-535.
    CrossRef  |  Direct Link  |  
  122. Li, X., H. Jin, M. Yang, G. Chen, Y. Shen and W. Zhang, 2010. Chemical constituents of Rhododendron primulaeflorum. Chem. Nat. Compounds, 46: 106-108.
    CrossRef  |  
  123. Hu, L., W. Xu, X. Zhang, J. Su, X. Liu, H. Li and W. Zhang, 2010. In-vitro and in-vivo evaluations of cytochrome P450 1A2 interactions with nuciferine. J. Pharmacy Pharmacol., 62: 658-662.
    CrossRef  |  Direct Link  |  
  124. Fu, J.J., J.J. Qin, Q. Zeng, Y. Huang, H.Z. Jin and W.D. Zhang, 2010. Four new sesquiterpenoids from the roots of Incarvillea arguta and their inhibitory activities against LPS-stimulated NO production. Chem. Pharm. Bull., 58: 1263-1266.
  125. Chen, Y.Q., W.D. Zhang, L.Y. Kong, T. Lu and Y.H. Shen, 2010. Delavayol, a novel sesquiterpene from Incarvillea delavayi Bureau et Franchet. Nat. Prod. Res., 24: 915-919.
    CrossRef  |  
  126. Chen, M., J.J. Qin, J.J. Fu, X.J. Hu, X.H. Liu, W.D. Zhang and H.Z. Jin, 2010. Blumeaenes A-J, sesquiterpenoid esters from Blumea balsamifera with NO inhibitory activity. Planta Medica, 76: 897-902.
    CrossRef  |  Direct Link  |  
  127. Zhang, X., L. Shan, H. Huang, X. Yang and X. Liang et al., 2009. Rapid identification of acetophenones in two Cynanchum species using liquid chromatography-electrospray ionization tandem mass spectrometry. J. Pharm. Biomed. Anal., 49: 715-725.
    PubMed  |  
  128. Zhang, X., H. Huang, X. Liang, H. Huang and W. Dai et al., 2009. Analysis of Amaryllidaceae alkaloids from Crinum by high-performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry. Rapid Commun. Mass Spectrometry, 23: 2903-2916.
    CrossRef  |  Direct Link  |  
  129. Zeng, H., X. Liu, S. Dou, W. Xu and N. Li et al., 2009. Huang-Lian-Jie-Du-Tang exerts anti-inflammatory effects in rats through inhibition of nitric oxide production and eicosanoid biosynthesis via the lipoxygenase pathway. J. Pharmacy Pharmacol., 61: 1699-1707.
    CrossRef  |  Direct Link  |  
  130. Ye, J., X. Zhang, W. Dai, S. Yan and H. Huang et al., 2009. Chemical fingerprinting of Liuwei Dihuang Pill and simultaneous determination of its major bioactive constituents by HPLC coupled with multiple detections of DAD, ELSD and ESI-MS. J. Pharm. Biomed. Anal., 49: 638-645.
    PubMed  |  
  131. Yang, X.W., Y. Ding, X.C. Li, D. Ferreira and Y.H. Shen et al., 2009. Cycloabiesesquine A, a unique sesquiterpenoid from Abies delavayi. Chem. Commun., 25: 3771-3773.
    CrossRef  |  
  132. Yan, S., Y. Yang, Y. Wu, R. Liu and W. Zhang, 2009. Chemical fingerprinting and quantitative analysis of volatiles in Shexiang Baoxin Pill by gas chromatography with flame ionization and mass spectrometric detection. J. Anal. Chem., 64: 149-155.
    CrossRef  |  Direct Link  |  
  133. Yan, S., B. Wu, Z. Lin, H. Jin and J. Huang et al., 2009. Metabonomic characterization of aging and investigation on the anti-aging effects of total flavones of Epimedium. Mol. BioSyst., 5: 1204-1213.
    CrossRef  |  Direct Link  |  
  134. Xu, X.H., J.F. Zhou, T.Z. Li, Z.H. Zhang and L. Shan et al., 2009. Polygalasaponin G promotes neurite outgrowth of cultured neuron on myelin. Neurosci. Lett., 460: 41-46.
    PubMed  |  
  135. Wang, Y., M.L. Xu, H.Z. Jin, J.J. Fu and X.J. Hu et al., 2009. A new Nor-sesquiterpene lactone from Ainsliaea fulvioides. Chinese Chem. Lett., 20: 586-588.
    Direct Link  |  
  136. Tian, J.M., Y.H. Shen, X.W. Yang, S. Liang, J. Tang, L. Shan and W.D. Zhang, 2009. Tunicyclin A, the first plant tricyclic ring cycloheptapeptide from Psammosilene tunicoides. Organic Lett., 11: 1131-1133.
    CrossRef  |  Direct Link  |  
  137. Sun, Q., Y.H. Shen, J.M. Tian, J. Tang and J. Su et al., 2009. Chemical constituents of Crinum asiaticum L. var. sinicumBaker and their cytotoxic activities. Chem. Biodiversity, 6: 1751-1757.
    CrossRef  |  Direct Link  |  
  138. Su, Y.Q., Y.H. Shen, T. Jian and W.D. Zhang, 2009. Two new alkaloids from Incarvillea mairei var. granditlora (Wehrhahn) grierson. Helvetica Chimica Acta, 92: 165-170.
    CrossRef  |  
  139. Su, J., C. Zhang, W. Zhang, Y.H. Shen and H.L. Li et al., 2009. Qualitative and quantitative determination of the major coumarins in Zushima by high performance liquid chromatography with diode array detector and mass spectrometry. J. Chromatography A, 1216: 2111-2117.
    CrossRef  |  Direct Link  |  
  140. Shen, Y.H., Y. Zhou, C. Zhang, R.H. Liu, J. Su, X.H. Liu and W.D. Zhang, 2009. Antidepressant effects of methanol extract and fractions of Bacopa monnieri. Pharm. Biol., 47: 340-343.
    Direct Link  |  
  141. Qin, J.J., J.X. Zhu, W.D. Zhang, Y. Zhu, J.J. Fu, X.H. Liu and H.Z. Jin, 2009. A new Ent-kaurane type diterpenoid glycoside from Inula japonica Thunb. Arch. Pharmacal Res., 32: 1369-1372.
    CrossRef  |  Direct Link  |  
  142. Qin, J.J., H.Z. Jin, J.J. Fu, X.J. Hu, Y. Wang, S.K. Yan and W.D. Zhang, 2009. Japonicones A-D, bioactive dimeric sesquiterpenes from Inula japonica. Bioorganic Med. Chem. Lett., 19: 710-713.
  143. Mao, Y.F., X.R. Liu, S.K. Yan, H. Xu, Y.C. Xiong and W.D. Zhang, 2009. Blood serum profiling of gabapentin treatment neuralgia rat models using Ultra-performance liquid chromatography/time-of-flight mass spectrometry. Eur. J. Pharmacol., 615: 61-65.
  144. Lu, X., Y. Shen, Y. Zhu, Q. Xu and X. Liu et al., 2009. Diketopiperazine constituents of marine Bacillus subtilis. Chem. Nat. Compounds, 45: 290-292.
    CrossRef  |  Direct Link  |  
  145. Lu, T., Y.H. Shen, M. Lu, J. Tang and L. Shan et al., 2009. Three new compounds from Incarvillea delavayi. Helvetica Chimica Acta, 92: 768-773.
    CrossRef  |  Direct Link  |  
  146. Liu, R., H. Luo, Y. Li, M. Yang and X. Xu et al., 2009. N-containing compounds from the traditional Chinese medicine ChanSu. Chem. Nat. Compounds, 45: 599-600.
    CrossRef  |  Direct Link  |  
  147. Liu, J.H., J.J. Qin, H.Z. Jin, X.J. Hu and M. Chen et al., 2009. A new triterpenoid from Brucea javanica. Arch. Pharmacal Res., 32: 661-666.
    CrossRef  |  Direct Link  |  
  148. Liu, J.H., H.Z. Jin, W.D. Zhang, S.K. Yan and Y.H. Shen, 2009. Chemical constituents of plants from the genus Brucea. Chem. Biodiversity, 6: 57-70.
    CrossRef  |  
  149. Liu, C.M., R.L. Zhu and W.D. Zhang, 2009. cis-Clerodane-type diterpenoids from the liverwort Gottschelia schizopleura. Planta Medica, 75: 1597-1601.
  150. Lin, Z.Y., P.B. Xu, S.K. Yan, H.B. Meng and G.J. Yang et al., 2009. A metabonomic approach to early prognostic evaluation of experimental sepsis by 1H NMR and pattern recognition. NMR Biomed., 22: 601-608.
    CrossRef  |  Direct Link  |  
  151. Lin, S., Y.H. Shen, H.L. Li, X.W. Yang and T. Chen et al., 2009. Acylated iridoids with cytotoxicity from Valeriana jatamansi. J. Nat. Prod., 72: 650-655.
    CrossRef  |  Direct Link  |  
  152. Liang, X., X. Zhang, W. Dai, Y. Lv, S. Yan and W. Zhang, 2009. A combined HPLC-PDA and HPLC-MS method for quantitative and qualitative analysis of 10 major constituents in the traditional Chinese medicine Zuo Gui Wan. J. Pharm. Biomed. Anal., 49: 931-936.
    PubMed  |  
  153. Liang, S., Y.H. Shen, J.M. Tian, Z.J. Wu, H.Z. Jin, W.D. Zhang and S.K. Yan, 2009. Three new dicoumarins from Daphne feddei. Helvetica Chimica Acta, 92: 133-138.
    CrossRef  |  
  154. Li, Y.L., X.W. Yang, S.M. Li, Y.H. Shen and H.W. Zeng et al., 2009. Terpenoid constituents of Abies chensiensis with potential Anti-inflammatory activity. J. Nat. Prod., 72: 1065-1068.
    CrossRef  |  Direct Link  |  
  155. Li, Y.L., X.W. Yang, S.M. Li, J. Tang and J.M. Tian et al., 2009. Two new spirobiflavonoids from Abies chensiensis with moderate NO production inhibitory activity. Planta Medica, 75: 1534-1537.
    CrossRef  |  PubMed  |  
  156. Li, S.M., X.W. Yang, Y.L. Li, Y.H. Shen and L. Feng et al., 2009. Chemical constituents of Dracocephalum forrestii. Planta Medica, 75: 1591-1596.
    CrossRef  |  Direct Link  |  
  157. Li, H.Y., W. Xu, X. Zhang, W.D. Zhang and L.W. Hu, 2009. Bufalin inhibits CYP3A4 activity in vitro and in vivo. Acta Pharmacologica Sinica, 30: 646-652.
    CrossRef  |  Direct Link  |  
  158. Li, H.Y., W. Xu, H.L. Li, W.D. Zhang and L.W. Hu, 2009. LC-MS-MS method for the determination of protoveratrine A in rat plasma. Chromatographia, 69: 523-529.
    Direct Link  |  
  159. Li, H.L., J. Tang, R.H. Liu, C. Zhang and W.D. Zhang, 2009. Two new flavanone glycosides from Veratrum nigrum L. Nat. Prod. Res., 23: 122-126.
    CrossRef  |  Direct Link  |  
  160. Jin, H.Z., G. Chen, X.F. Li, Y.H. Shen and S.K. Yan et al., 2009. Flavonoids from Rhododendron decorum. Chem. Nat. Compounds, 45: 85-86.
    CrossRef  |  
  161. Jiang, P., S. Dou, L. Liu, W. Zhang and Z. Chen et al., 2009. Identification of multiple constituents in the TCM-formula shexiang baoxin pill by LC coupled with DAD-ESI-MS-MS. Chromatographia, 70: 133-142.
    CrossRef  |  Direct Link  |  
  162. Jiang, P., R. Liu, S. Dou, L. Liu, W. Zhang, Z. Chen, R. Xu and J. Ding, 2009. Analysis of the constituents in rat plasma after oral administration of Shexiang Baoxin pill by HPLC-ESI-MS/MS. Biomed. Chromatogr., 23: 1333-1343.
    CrossRef  |  
  163. Huang, Z.S., Y.H. Pei, Y.H. Shen, S. Lin, C.M. Liu and W.D. Zhang, 2009. Cyclohexyl-ethanol derivatives from the roots of Incarvillea mairei (Levl.) Grierson. J. Asian Nat. Prod. Res., 11: 523-528.
  164. Huang, H.Q., X. Zhang, Z.X. Xu, J. Su, S.K. Yan and W.D. Zhang, 2009. Fast determination of saikosaponins in Bupleurum by rapid resolution liquid chromatography with evaporative light scattering detection. J. Pharm. Biomed. Anal., 49: 1048-1055.
  165. Huang, H.Q., X. Zhang, Y.H. Shen, J. Su and X.H. Liu et al., 2009. Polyacetylenes from Bupleurum longiradiatum. J. Nat. Prod., 72: 2153-2157.
    CrossRef  |  Direct Link  |  
  166. Huang, H., M.J. Liang, H. Luo and W.D. Zhang, 2009. Simultaneous determination of bufadienolides and qualitative evaluation for venenum bufonis by high performance liquid chromatography. Chem. Res. Chinese Univ., 25: 801-806.
  167. Huang, D.S., W.D. Zhang, Y.H. Pei, X.Y. Peng, Z.S. Huang, H.L. Li and Y.H. Shen, 2009. Two new alkaloids from Incarvillea sinensis. Helvetica Chimica Acta, 92: 1558-1561.
    CrossRef  |  
  168. Hu, X.J., H.Z. Jin, W.D. Zhang, W. Zhang and S.K. Yan et al., 2009. Two new coumarins from Edgeworthia chrysantha. Natural Prod. Res., 23: 1259-1264.
    CrossRef  |  Direct Link  |  
  169. Hu, X.J., H. Jin, W. Zhang, S. Yan and W. Xu et al., 2009. Chemical constituents of Edgeworthia chrysantha. Chem. Nat. Compounds, 45: 126-128.
    CrossRef  |  Direct Link  |  
  170. Ge, X., D.C. Lin, W.D. Zhang and X.R. Zhang, 2009. Triterpenoid saponins and monoterpenoid glycosides from Incarvillea delavayi. J. Asian Nat. Prod. Res., 11: 838-844.
    CrossRef  |  Direct Link  |  
  171. Fu, P., S. Lin, L. Shan, M. Lu and Y.H. Shen et al., 2009. Constituents of the moss Polytrichum commune. J. Nat. Prod., 72: 1335-1337.
    CrossRef  |  Direct Link  |  
  172. Fu, P., C.C. Zhao, J. Tang, Y.H. Shen, X.K. Xu and W.D. Zhang, 2009. New flavonoid glycosides and cyanogenic glycosides from Dracocephalum peregrinum. Chem. Pharm. Bull., 57: 207-210.
    CrossRef  |  Direct Link  |  
  173. Fu, J.J., H.Z. Jin, Y.H. Shen, J.J. Qin and Y. Wang et al., 2009. Two new cytotoxic biphenyls from the roots of Incarvillea arguta. Helvetica Chimica Acta, 92: 491-494.
    CrossRef  |  Direct Link  |  
  174. Fu, J.J., H.Z. Jin, Y.H. Shen, J.J. Qin and Y. Wang et al., 2009. Chemical constituents of plants from the genus Incarvillea. Chem. Biodiversity, 6: 818-826.
    CrossRef  |  Direct Link  |  
  175. Dou, S., L. Liu, P. Jiang, W. Zhang and R. Liu, 2009. LC-DAD and LC-ESI-MS chromatographic fingerprinting and quantitative analysis for evaluation of the quality of Huang-Lian-Jie-Du-Tang. Chromatographia, 69: 659-664.
    CrossRef  |  
  176. Dai, L.M., J. Tang, H.L. Li, Y.H. Shen, C.Y. Peng and W.D. Zhang, 2009. A new stilbene glycoside from the n-butanol fraction of Veratrum dahuricum. Chem. Nat. Compounds, 45: 325-329.
    CrossRef  |  Direct Link  |  
  177. Chen, Y.Q., Y.H. Shen, Y.Q. Su, L.Y. Kong and W.D. Zhang, 2009. Incarviditone: A novel cytotoxic benzofuranone dimer from Incarvillea delavayibureau et franchet. Chem. Biodiversity, 6: 779-783.
    CrossRef  |  Direct Link  |  
  178. Chen, M., H.Z. Jin, W.D. Zhang, S.K. Yan and Y.H. Shen, 2009. Chemical constituents of plants from the genus Blumea. Chem. Biodiversity, 6: 809-817.
    CrossRef  |  Direct Link  |  
  179. Chen, G., H. Jin, X. Li, Q. Zhang, Y. Shen, S. Yan and W. Zhang, 2009. Chemical constituents from Rhododendron spinuliferum. Chem. Nat. Compounds, 45: 725-727.
    CrossRef  |  Direct Link  |  
  180. Zhang, Y.P., W. Xu, N. Li, H.Y. Li and Z.Y. Shen et al., 2008. LC-MS-MS method for simultaneous determination of icariin and its active metabolite icariside II in human plasma. Chromatographia, 68: 245-250.
    CrossRef  |  Direct Link  |  
  181. Zhang, Y., L. Shan, W. Xu, M. Yang, W. Zhang and H. Li, 2008. LC-MS/MS method for the determination of cynandione A in rat plasma and tissues. Biomed. Chromatogr., 22: 1173-1179.
    CrossRef  |  
  182. Zhang, W.D., H.Z. Jin, G. Chen, X.F. Li, S.K. Yan, 2008. A new grayanane diterpenoid from Rhododendron decorum. Fitoterapia, 79: 602-604.
    CrossRef  |  Direct Link  |  
  183. Yang, X.W., S.M. Li, Y.H. Shen and W.D. Zhang, 2008. Phytochemical and biological studies of Abies species. Chem. Biodiversity, 5: 56-81.
    CrossRef  |  Direct Link  |  
  184. Yang, X.W., S.M. Li, L. Feng, Y.H. Shen and J.M. Tian et al., 2008. Abiesanordines A-N: Fourteen new norditerpenes from Abies georgei. Tetrahedron, 64: 4354-4362.
    CrossRef  |  Direct Link  |  
  185. Yang, X.W., S.M. Li, L. Feng, Y.H. Shen and J.M. Tian et al., 2008. Abiesanol A, a novel biflavanol with unique six connective hexacyclic rings isolated from Abies georgei. Tetrahedron Lett., 49: 3042-3044.
    CrossRef  |  Direct Link  |  
  186. Yang, X.W., H.W. Zeng, X.H. Liu, S.M. Li, W. Xu, Y.H. Shen, C. Zhang and W.D. Zhang, 2008. Anti-inflammatory and Anti-tumour effects of Abies georgei extracts. J. Pharmacy Pharmacol., 60: 937-941.
    CrossRef  |  
  187. Yang, F., S. Yan, Y. He, F. Wang and S. Song et al., 2008. Expression of HBV proteins in transgenic mice disturbs liver lipid metabolism and induces oxidative stress. J. Hepatol., 48: 12-19.
  188. Yang, F., S. Yan, F. Wang, Y. He and Y. Guo et al., 2008. DNA immunization perturbs lipid metabolites and increases risk of atherogenesis. J. Proteome Res., 7: 741-748.
    CrossRef  |  Direct Link  |  
  189. Yan, S.K., B.J. Wei, Z.Y. Lin, Y. Yang, Z.T. Zhou and W.D. Zhang, 2008. A metabonomic approach to the diagnosis of oral squamous cell carcinoma, oral lichen planus and oral leukoplakia. Oral Oncol., 44: 477-483.
    CrossRef  |  Direct Link  |  
  190. Xu, W., L. Shan, X. Liu, H. Li, L. Hu and W. Zhang, 2008. Determination of two C21 steroidal glycosides of Baishouwu and their metabolites in mice plasma and tumor homogenate by liquid chromatography-tandem mass spectrometry. J. Chromatography B, 876: 203-210.
    CrossRef  |  Direct Link  |  
  191. Xu, W., H. Jin, W. Zhang, X. Hu and W. Zhang et al., 2008. Chemical constituents from Daphne pedunculata. Chem. Nat. Compounds, 44: 771-771.
  192. Xu, P.B., Z.Y. Lin, H.B. Meng, S.K. Yan and Y. Yang et al., 2008. A metabonomic approach to early prognostic evaluation of experimental sepsis. J. Infect., 56: 474-481.
    CrossRef  |  Direct Link  |  
  193. Wu, Z.J., X.K. Xu, Y.H. Shen, J. Su and J.M. Tian et al., 2008. Ainsliadimer A, a new sesquiterpene lactone dimer with an unusual carbon skeleton from Ainsliaea macrocephala. Organic Lett., 10: 2397-2400.
    CrossRef  |  Direct Link  |  
  194. Wu, B., S. Yan, Z. Lin, Q. Wang and Y. Yang et al., 2008. Metabonomic study on ageing: NMR-based investigation into rat urinary metabolites and the effect of the total flavone of Epimedium. Mol. BioSyst., 4: 855-861.
    CrossRef  |  Direct Link  |  
  195. Wang, Y., Y.H. Shen, H.Z. Jin, J.J. Fu and X.J. Hu et al., 2008. Ainsliatrimers A and B, the first two guaianolide trimers from Ainsliaea fulvioides. Organic Lett., 10: 5517-5520.
    CrossRef  |  Direct Link  |  
  196. Wang, T., N.L. Sun, W.D. Zhang, H.L. Li and G.C. Lu et al., 2008. Protective effects of dehydrocavidine on carbon tetrachloride-induced acute hepatotoxicity in rats. J. Ethnopharmacol., 117: 300-308.
    CrossRef  |  Direct Link  |  
  197. Wang, B., W.D. Zhang, Y.H. Shen, J. Tang, C. Zhang, R.H. Liu, M. Lin and H.L. Li, 2008. Two new steroidal alkaloids from Veratrum nigrum L. HCA, 91: 244-248.
    CrossRef  |  Direct Link  |  
  198. Tang, J., H.L. Li, Y.H. Shen, R.H. Liu, X.K. Xu and W.D. Zhang, 2008. Steroid alalkaloids from veratrum dahuricum. Chem. Nat. Compounds, 44: 407-408.
  199. Tang, J., H.L. Li, Y.H. Shen, H.Z. Jin, S.K. Yan, R.H. Liu and W.D. Zhang, 2008. Simultaneous determination of six steroidal alkaloids of Veratrum dahuricum by HPLC-ELSD and HPLC-MSn. Chromatographia, 67: 15-21.
    CrossRef  |  Direct Link  |  
  200. Tang, J., H.L. Li, Y.H. Shen, H.Z. Jin, S.K. Yan, R.H. Liu and W.D. Zhang, 2008. Antitumor activity of extracts and compounds from the rhizomes of Veratrum dahuricum. Phytother. Res., 22: 1093-1096.
    CrossRef  |  Direct Link  |  
  201. Sun, Q., W.D. Zhang, Y.H. Shen, C. Zhang and H.L. Li, 2008. A new phenolic compound from Crinum asiaticum L. Chinese Chem. Lett., 19: 447-449.
    CrossRef  |  Direct Link  |  
  202. Su, Y.Q., W.D. Zhang, C. Zhang, R.H. Liu and Y.H. Shen, 2008. A new caffeic ester from Incarvillea mairei var.granditlora(Wehrhahn) grierson. Chinese Chem. Lett., 19: 829-831.
    CrossRef  |  Direct Link  |  
  203. Su, J., Z.J. Wu, Y.H. Shen, C. Zhang, H.L. Li, R.H. Liu and W.D. Zhang, 2008. Three new flavanols from Daphne giraldii. J. Asian Nat. Prod. Res., 10: 547-550.
    CrossRef  |  Direct Link  |  
  204. Su, J., Z.J. Wu, W.D. Zhang, C. Zhang, H.L. Li, R.H. Liu and Y.H. Shen, 2008. Two new Bis-coumarin glycosides from Daphne giraldii NITSCHE. Chem. Pharm. Bull., 56: 589-591.
    CrossRef  |  Direct Link  |  
  205. Su, J., Z. Wu, Y. Shen, R. Liu, Z. Chuan and W. Zhang, 2008. Flavonoids from Daphne giraldii nitsche. Nat. Prod. Res., 22: 1355-1358.
    CrossRef  |  Direct Link  |  
  206. Su, J., Z. Wu, Y. Shen, C. Zhang and W. Zhang, 2008. Lignans from Daphne giraldii. Chem. Nat. Compounds, 44: 648-650.
    CrossRef  |  Direct Link  |  
  207. Su, J., P. Fu, Y. Shen, C. Zhang, M. Liang, R. Liu, H. Li and W. Zhang, 2008. Simultaneous analysis of flavonoids from Hypericum japonicum Thunb.ex Murray (Hypericaceae) by HPLC-DAD-ESI/MS. J. Pharm. Biomed. Anal., 46: 342-348.
    Direct Link  |  
  208. Qin, J.J., H.Z. Jin, J.J. Fu, X.J. Hu and Y. Zhu et al., 2008. Anthranilic acid derivatives from Inula japonica. Chinese Chem. Lett., 19: 556-558.
    CrossRef  |  Direct Link  |  
  209. Lu, Y.F., K.Y. Chen, H.L. Li, Y.H. Pei, R.H. Liu and W.D. Zhang, 2008. Biotransformation of Vermitaline by Cunninghamella echinulata. HCA, 91: 819-824.
    CrossRef  |  Direct Link  |  
  210. Lu, X.L., Q.Z. Xu, Y.H. Shen, X.Y. Liu, B.H. Jiao, W.D. Zhang and K.Y. Ni, 2008. Macrolactin S, a novel macrolactin antibiotic from marine Bacillus sp. Nat. Prod. Res., 22: 342-347.
    CrossRef  |  Direct Link  |  
  211. Liang, S., Y.H. Shen, J.M. Tian, Z.J. Wu, H.Z. Jin, W.D., Zhang and S.K. Yan, 2008. Phenylpropanoids from Daphne feddei and their inhibitory activities against NO production. J. Nat. Prod., 71: 1902-1905.
    CrossRef  |  Direct Link  |  
  212. Liang, S., J. Tang, Y.H. Shen, H.Z. Jin and J.M. Tian et al., 2008. Biflavonoids from daphne feddei and their inhibitory activities against nitric oxide production. Chem. Pharm. Bull., 56: 1729-1731.
    CrossRef  |  
  213. Liang, S., H.S. Chen, Y.H. Shen, W.D. Zhang, Y.S. Jin and R.H. Liu, 2008. Three new monoterpenoid indole alkaloids from Ervatamia flabelliformis. HCA, 91: 239-243.
    CrossRef  |  
  214. Liang, M., W. Zhang, C. Zhang, Y. Shen, X. Wang anf X. Wang, 2008. Simultaneous determination of vitexin rhamnoside and vitexin glucoside in rats by liquid chromatography coupled with mass spectrometry. Nat. Prod. Commun., 3: 677-682.
  215. Li, Y.L., X.W. Yang and W.D. Zhang, 2008. Stilbenes, lignans and phenols from Abies chensiensis. Biochem. Syst. Ecol., 36: 932-934.
  216. Li, S.M., X.W. Yang, Y.H. Shen, L. Feng and Y.H. Wang et al., 2008. Chemical constituents of Aeschynanthus bracteatus and their weak Anti-inflammatory activities. Phytochemistry, 69: 2200-2204.
    CrossRef  |  Direct Link  |  
  217. Li, H.L., T. Han, R.H. Liu, C. Zhang, H.S. Chen and W.D. Zhang, 2008. Alkaloids from corydalis saxicola and their Anti-hepatitis b virus activity. Chem. Biodiversity, 5: 777-783.
    CrossRef  |  Direct Link  |  
  218. Jin, H.Z., J.L. Du, W.D. Zhang, S.K. Yan, H.S. Chen, J.H. Lee and J.J. Lee, 2008. A new quinazolinedione alkaloid from the fruits of Evodia officinalis. Fitoterapia, 79: 317-318.
    CrossRef  |  Direct Link  |  
  219. Huang, H.Q., X. Zhang, M. Lin, Y.H. Shen, S. Yan and W.D. Zhang, 2008. Characterization and identification of triterpene saponins in crude extracts from three Bupleurum species by High-performance liquid chromatography/electrospray ionization with Multi-stage mass spectrometry. J. Separation Sci., 31: 3190-3201.
  220. Huang, H.Q., H.L. Li, J. Tang, Y.F. Lv and W.D. Zhang, 2008. A new aurone and other phenolic constituents from Veratrum schindleri Loes. f. Biochem. Syst. Ecol., 36: 590-592.
  221. Huang, H.Q., H.L. Li, J. Tang, B. Wang, Y.F. Lv, Y.H. Shen and W.D. Zhang, 2008. Steroidal alkaloids from Veratrum schindleri and Veratrum maackii. Biochem. Syst. Ecol., 36: 430-433.
  222. Huang, H., M. Liang, W. Xu, C. Zhang and W. Zhang, 2008. Identification and quantification of three tubeimosides in rhizoma bolbostematis by high performance liquid chromatography with evaporative light scattering detection and electrospray mass spectrometric detection. Nat. Prod. Commun., 3: 683-688.
  223. Hu, X.J., H.Z. Jin, W.Z. Xu, M. Chen and X.H. Liu et al., 2008. Anti-inflammatory and analgesic activities of Edgeworthia chrysantha and its effective chemical constituents. Biol. Pharm. Bull., 31: 1761-1765.
    CrossRef  |  Direct Link  |  
  224. Hu, X., H. Jin, W. Xu, W. Zhang and X. Liu et al., 2008. Anti-inflammatory and analgesic effects of Daphne retusa Hemsl. J. Ethnopharmacol., 120: 118-122.
    CrossRef  |  Direct Link  |  
  225. Dai, L.M., C.C. Zhao, H.Z. Jin, J. Tang and Y.H. Shen et al., 2008. A new ferulic acid ester and other constituents from Dracocephalum peregrinum. Arch. Pharm. Res., 31: 1325-1329.
    CrossRef  |  Direct Link  |  
  226. Chen, G., H.Z. Jin, X.F. Li, Q. Zhang, Y.H. Shen, S.K. Yan and W.D. Zhang, 2008. A new chromone glycoside from Rhododendron spinuliferum. Arch. Pharmacal Res., 31: 970-972.
    CrossRef  |  Direct Link  |  
  227. Zhou, Y., Y.H. Shen, C. Zhang, J. Su, R.H. Liu and W.D. Zhang, 2007. Triterpene saponins from Bacopa monnieri and their antidepressant effects in two mice models. J. Nat. Prod., 70: 652-655.
    CrossRef  |  Direct Link  |  
  228. Zhou, Y., Y.H. Shen, C. Zhang and W.D. Zhang, 2007. Chemical constituents of Bacopa monnieri. Chem. Nat. Compounds, 43: 355-357.
    CrossRef  |  Direct Link  |  
  229. Zheng, Z., W. Zhang, L. Kong, M. Liang and H. Li et al., 2007. Rapid identification of C21 steroidal saponins in Cynanchum versicolor Bunge by electrospray ionization multi‐stage tandem mass spectrometry and liquid chromatography/tandem mass spectrometry. Rapid Commun. Mass Spectrom., 21: 279-285.
    CrossRef  |  Direct Link  |  
  230. Zhang, W.D., P. Fu, R.H. Liu, T.Z. Li, H.L. Li W. Zhang and H.S. Chen, 2007. A new bisxanthone from Hypericum japonicum. Fitoterapia, 78: 74-75.
    Direct Link  |  
  231. Zhang, W., Y. Shen, R. Liu, C. Zhang and H. Chen et al., 2007. Coumarins from the bark of Daphne marginata. Chem. Nat. Compounds, 43: 317-318.
    CrossRef  |  Direct Link  |  
  232. Zhang, W., W.D. Zhang, C. Zhang, R.H. Liu, T.Z. Li, P. Fu and L. Shan, 2007. Antitumor activities of extracts and compounds from the roots of Daphne tangutica maxim. Phytother. Res., 21: 1113-1115.
    PubMed  |  
  233. Zhang, W., Q. Shi, Y. Shen and H. Chen, 2007. A new flavanol from Daphne genkwa. Fitoterapia, 78: 596-597.
    CrossRef  |  Direct Link  |  
  234. Zhang, C., X.H. Wang, M.F. Zhong, R.H. Liu, H.L. Li, W.D. Zhang and H. Chen, 2007. Mechanisms underlying vasorelaxant action of astragaloside IV in isolated rat aortic rings. Clin. Exp. Pharmacol. Physiol., 34: 387-392.
    CrossRef  |  
  235. Yang, Y., S.K. Yan, Z.Y. Lin, W.D. Zhang and Q.R. Shi, 2007. Separation and determination of major bioactive components in radix tinosporae by gradient pressurized capillary electrochromatography. J. Liquid Chromatography Related Technol., 30: 2669-2679.
    CrossRef  |  Direct Link  |  
  236. Yan, S.K., Y.W. Wu, R.H. Liu and W.D. Zhang, 2007. Comparative study on major bioactive components in natural, artificial and in-vitro cultured Calculus Bovis. Chem. Pharm. Bull., 55: 128-132.
    CrossRef  |  Direct Link  |  
  237. Xu, W., Y. Zhang, M. Yang, Z. Shen, X. Zhang, W. Zhang and H. Li, 2007. LC-MS/MS method for the simultaneous determination of icariin and its major metabolites in rat plasma. J. Pharm. Biomed. Anal., 45: 667-672.
    CrossRef  |  Direct Link  |  
  238. Xu, W., H. Luo, Y. Zhang, L. Shan and H. Li et al., 2007. Simultaneous determination of five main active bufadienolides of Chan Su in rat plasma by liquid chromatography tandem mass spectrometry. J. Chromatography B, 859: 157-163.
    CrossRef  |  Direct Link  |  
  239. Tang, J., H.L. Li, Y.L. Li and W.D. Zhang, 2007. Flavonoids from rhizomes of Veratrum dahuricum. Chem. Nat. Compounds, 43: 696-697.
    CrossRef  |  Direct Link  |  
  240. Tang, J., H.L. Li, Y.H. Shen, H.Z. Jin, S.K. Yan, R.H. Liu and W.D. Zhang, 2007. Four new germine esters from Veratrum dahuricum. HCA, 90: 769-775.
    CrossRef  |  Direct Link  |  
  241. Su, J., Z.J. Wu, R.H. Liu, Y.H. Shen and C. Zhang et al., 2007. A new coumarin glycoside from Daphne giraldii. Chinese Chem. Lett., 18: 835-836.
    CrossRef  |  Direct Link  |  
  242. Shi, Q., S. Yan, M. Liang, Y. Yang, Y. Wang and W. Zhang, 2007. Simultaneous determination of eight components in Radix Tinosporae by high-performance liquid chromatography coupled with diode array detector and electrospray tandem mass spectrometry. J. Pharm. Biomed. Anal., 43: 994-999.
    CrossRef  |  Direct Link  |  
  243. Shi, Q., M. Liang, W. Zhang, C. Zhang and R. Liu et al., 2007. Quantitative LC/MS/MS method and pharmacokinetic studies of columbin, an Anti-inflammation furanoditerpen isolated from radix tinosporae. Biomed. Chromatogr., 21: 642-648.
    CrossRef  |  
  244. Lu, T., W.D. Zhang, Y.H. Pei, C. Zhang, J.C. Li and Y.H. Shen, 2007. A new iridoid from Incarvillea delavayi. Chinese Chem. Lett., 18: 1512-1514.
    CrossRef  |  Direct Link  |  
  245. Liu, R.H., H. Luo, Y.L. Li, M. Yang and H.L. Li et al., 2007. Three new alkaloids from the traditional chinese medicine chansu. HCA, 90: 2427-2431.
    CrossRef  |  Direct Link  |  
  246. Liu, R., J. Zhang, M. Liang, W. Zhang, S. Yan and M. Lin, 2007. Simultaneous analysis of eight bioactive compounds in Danning tablet by HPLC-ESI-MS and HPLC-UV. J. Pharm. Biomed. Anal., 43: 1007-1012.
    CrossRef  |  Direct Link  |  
  247. Liang, S., H.S. Chen, L. Jin and W.D. Zhang, 2007. Flabelliformide A and B, two novel indole alkaiods from Ervatamia flabllformis. Helvetica Chimica Acta, 90: 1467-1470.
  248. Liang, M.J., W.D. Zhang, C. Zhang, R.H. Liu and Y.H. Shen et al., 2007. Quantitative determination of the anticancer agent tubeimoside I in rat plasma by liquid chromatography coupled with mass spectrometry. J. Chromatography B, 845: 84-89.
    CrossRef  |  Direct Link  |  
  249. Liang, M., Z. Zheng, Y. Yuan, L. Kong and Y. Shen et al., 2007. Identification and quantification of C21 steroidal saponins from radix cynanchi atrati by high‐performance liquid chromatography with evaporative light scattering detection and electrospray mass spectrometric detection. Phytochem. Anal., 18: 428-435.
    CrossRef  |  Direct Link  |  
  250. Liang, M., W. Xu, W. Zhang, C. Zhang and R. Liu et al., 2007. Quantitative LC/MS/MS method and in vivo pharmacokinetic studies of vitexin rhamnoside, a bioactive constituent on cardiovascular system from hawthorn. Biomed. Chromatogr., 21: 422-429.
    CrossRef  |  Direct Link  |  
  251. Liang, M., J. Zhang, R. Liu, S. Yan, W. Zhang and M. Lin, 2007. Chemical profile of danning tablets by LC-dad coupled with ESI-MS. Chromatographia, 66: 107-110.
    CrossRef  |  Direct Link  |  
  252. Li, H.L., W.D. Zhang, T. Han, C. Zhang, R.H. Liu and H.S. Chen, 2007. Tetrahydroprotoberberine alkaloids from Corydalis saxicola. Chem. Nat. Compounds, 43: 173-175.
    CrossRef  |  Direct Link  |  
  253. Li, H.L., W.D. Zhang, C. Zhang, T. Han, R.H. Liu, J. Hu and H.S. Chen, 2007. Comparative analysis of the chemical profile of wild and cultivated populations of Corydalis saxicola by high‐performance liquid chromatography. Phytochem. Anal., 18: 393-400.
    CrossRef  |  Direct Link  |  
  254. Li, H.L., J. Tang, R.H. Liu, M. Lin and B. Wang et al., 2007. Characterization and identification of steroidal alkaloids in the Chinese herb Veratrum nigrum L. by High-performance liquid chromatography/electrospray ionization with Multi-stage mass spectrometry. Rapid Commun. Mass Spectrom., 21: 869-879.
    CrossRef  |  
  255. Jin, H.Z., J.L. Du, W.D. Zhang, H.S. Chen, J.H. Lee and J.J. Lee, 2007. A novel alkaloid from the fruits of Evodia officinalis. J. Asian Nat. Prod. Res., 9: 685-688.
    CrossRef  |  Direct Link  |  
  256. Jin, H.Z., J.H. Lee, W.D. Zhang, H.B. Lee, Y.S. Hong, Y.H. Kim and J.J. Lee, 2007. Harzianums A and B produced by a fungal strain, Hypocrea sp. F000527 and their cytotoxicity against tumor cell lines. J. Asian Nat. Prod. Res., 9: 203-207.
    CrossRef  |  Direct Link  |  
  257. Huang, H., M. Liang, X. Zhang, C. Zhang, Z. Shen and W. Zhang, 2007. Simultaneous determination of nine flavonoids and qualitative evaluation of Herba Epimedii by high performance liquid chromatography with ultraviolet detection. J. Separation Sci., 30: 3207-3213.
    CrossRef  |  Direct Link  |  
  258. Hu, J., W.D. Zhang, Y.H. Shen, C. Zhang, R.H. Liu, X.K. Xu and B. Wang, 2007. Two novel alkaloids from Zanthoxylum nitidum. Helvetica Chim. Acta, 90: 720-722.
    CrossRef  |  Direct Link  |  
  259. Hu, J., W.D. Zhang, Y.H. Shen, C. Zhang, L. Xu and R.H. Liu, 2007. Alkaloids from Zanthoxylum nitidum (Roxb.) DC. Biochem. System. Ecol., 35: 114-117.
  260. Fu, J.J., H.Z. Jin, Y.H. Shen, W.D. Zhang, W.Z. Xu, Q. Zeng and S.K. Yan, 2007. Two novel monoterpene alkaloid dimers from Incarvillea arguta. HCA, 90: 2151-2155.
    CrossRef  |  Direct Link  |  
  261. Zheng, Z.G., R.H. Liu, L.Y. Kong and W.D. Zhang, 2006. A novel C21 steroidal saponin from Cynanchum versicolor Bunge. Chinese Chem. Lett., 17: 919-921.
  262. Zhang, Y., Q. Shi, P. Shi, W. Zhang and Y. Cheng, 2006. Characterization of isoquinoline alkaloids, diterpenoids and steroids in the Chinese herb Jin‐Guo‐Lan (Tinospora sagittata and Tinospora capillipes by high‐performance liquid chromatography/electrospray ionization with multistage mass spectrometry. Rapid Commun. Mass Spectrom., 20: 2328-2342.
    CrossRef  |  Direct Link  |  
  263. Zhang, W.D., H. Chen, C. Zhang, R.H. Liu, H.L. Li and H.Z. Chen, 2006. Astragaloside IV from Astragalus membranaceus shows cardioprotection during myocardial ischemia in vivo and in vitro. Planta Med., 72: 4-8.
    CrossRef  |  
  264. Zhang, W.D., C. Zhang, X.H. Wang, P.J. Gao and D.L. Zhu et al., 2006. Astragaloside IV dilates aortic vessels from normal and spontaneously hypertensive rats through endothelium-dependent and endothelium-independent ways. Planta Med., 72: 621-626.
  265. Zhang, W.D., C. Zhang, R.H. Liu, H.L. Li and J.T. Zhang et al., 2006. Preclinical pharmacokinetics and tissue distribution of a natural cardioprotective agent astragaloside IV in rats and dogs. Life Sci., 79: 808-815.
    CrossRef  |  Direct Link  |  
  266. Zhang, W., W.D. Zhang, R.H. Liu, Y.H. Shen and C. Zhang et al., 2006. Two new chemical constituents from Daphne odora Thunb. var. marginata. Nat. Prod. Res., 20: 1290-1294.
    CrossRef  |  Direct Link  |  
  267. Zhang, W., T. Li, R. Liu, G. Yang and H. Chen, 2006. A new cerebroside from Polygala japonica. Fitoterapia, 77: 336-337.
    CrossRef  |  Direct Link  |  
  268. Yan, S.K., W.D. Zhang, R.H. Liu and Y.C. Zhan, 2006. Chemical fingerprinting of Shexiang Baoxin Pill and simultaneous determination of its major constituents by HPLC with evaporative light scattering detection and electrospray mass spectrometric detection. Chem. Pharm. Bull., 54: 1058-1062.
    CrossRef  |  Direct Link  |  
  269. Shi, P.Y., Y.F. Zhang, Q.R. Shi, M. Ishtiaq, W.D. Zhang and Y.Y. Cheng, 2006. Quantitative determination of three protoberberine alkaloids in Jin-Guo-Lan by high-performance liquid chromatography-diode array detector. Chromatographia, 64: 163-168.
  270. Shan, L., R.H. Liu, Y.H. Shen, W.D. Zhang and C. Zhang et al., 2006. Gastroprotective effect of a traditional Chinese herbal drug ''Baishouwu'' on experimental gastric lesions in rats. J. Ethnopharmacol., 107: 389-394.
    CrossRef  |  Direct Link  |  
  271. Liu, R.H., W.D. Zhang, Z.B. Gu, C. Zhang, J. Su and X.K. Xu, 2006. Two new iridoids from roots of Patrinia scabra Bung. Nat. Prod. Res., 20: 836-840.
    Direct Link  |  
  272. Liang, M., W. Zhang, J. Hu, R. Liu and C. Zhang, 2006. Simultaneous analysis of alkaloids from Zanthoxylum nitidum by high performance liquid chromatography-diode array detector -electrospray tandem mass spectrometry. J. Pharm. Biochem. Anal., 42: 178-183.
  273. Li, T.Z., W.D. Zhang, G.J. Yang, W.Y. Liu, R.H. Liu, C. Zhang and H.S. Chen, 2006. New flavonol glycosides and new xanthone from Polygala japonica. J. Asian Nat. Prod. Res., 8: 401-409.
    CrossRef  |  Direct Link  |  
  274. Li, T.Z., W.D. Zhang, G.J. Yang, W.Y. Liu, H.S. Chen and Y.H. Shen, 2006. Saponins from Polygala japonica and their effects on a forced swimming test in mice. J. Nat. Prod., 69: 591-594.
    CrossRef  |  Direct Link  |  
  275. Li, H.L., W.D. Zhang, R.H. Liu, C. Zhang and T. Han et al., 2006. Simultaneous determination of four active alkaloids from a traditional chinese medicine Corydalis saxicola Bunting.(Yanhuanglian) in plasma and urine samples by LC-MS-MS. J. Chromatogr. B, 831: 140-146.
    CrossRef  |  Direct Link  |  
  276. Li, H.L., W.D. Zhang, C. Zhang, R.H. Liu and X.W. Wang et al., 2006. Bioavailabilty and pharmacokinetics of four active alkaloids of traditional Chinese medicine Yanhuanglian in rats following intravenous and oral administration. J. Pharm. Biomed. Anal., 41: 1342-1346.
    CrossRef  |  Direct Link  |  
  277. Hu, J., W.D. Zhang, R.H. Liu, C. Zhang and Y.H. Shen et al., 2006. Benzophenanthridine alkaloids from Zanthoxylum nitidum (Roxb.) DC and their analgesic and anti-inflammatory activities. Chem. Biodiversity, 3: 990-995.
    CrossRef  |  
  278. Fu, P., W.D. Zhang, R.H. Liu, T.Z. Li and Y.H. Shen et al., 2006. Two new xanthones from Hypericum japonicum.q Nat. Prod. Res., 20: 1237-1240.
    CrossRef  |  Direct Link  |  
  279. Zhang, W., C. Zhang, R. Liu, H. Li, J. Zhang, C. Mao and C. Chen, 2005. Quantitative determination of Astragaloside IV, a natural product with cardioprotective activity, in plasma, urine and other biological samples by HPLC coupled with tandem mass spectrometry. J. Chromatogr. B, 822: 170-177.
    CrossRef  |  Direct Link  |  
  280. Yang, B.H., W.D. Zhang, R.H. Liu, T.Z. Li, C. Zhang, Y. Zhou and J. Su, 2005. Lignans from Bark of Larix olgensis var. koreana. J. Nat. Prod., 68: 1175-1179.
    CrossRef  |  Direct Link  |  
  281. Yang, B.H., W.D. Zhang, R.H. Liu, C.H. Tan and T.Z. Li et al., 2005. Spiro‐biflavonoids from Larix olgensis Henry var. koreanaNakai. Helvetica Chim. Acta, 88: 2892-2896.
    CrossRef  |  Direct Link  |  
  282. Tan, X.Q., H.S. Chen, R.H. Liu, C.H. Tan, C.L. Xu, W.D. Xuan and W.D. Zhang, 2005. Lignans from Trachelospermum jasminoides. Planta Med., 71: 93-95.
    CrossRef  |  
  283. Shan, L., W.D. Zhang, C. Zhang, R.H. Liu, J. Su and Y. Zhou, 2005. Antitumor activity of crude extract and fractions from root tuber of Cynanchum auriculatum Royle ex Wight. Phytother. Res., 19: 259-261.
    CrossRef  |  Direct Link  |  
  284. Li, H.L., W.D. Zhang, W. Zhang, C. Zhang and R.H. Liu, 2005. A new nitro alkaloid from Corydalis saxicola Bunting. Chinese Chem. Lett., 16: 367-368.
  285. Fu, P., W.D. Zhang, T.Z. Li, R.H. Liu, H.L. Li, W. Zhang and H.S. Chen, 2005. A new bisxanthone from Hypericum japonicum Thunb. Ex Murray. Chinese Chem. Lett., 16: 771-773.
  286. Franek, K.J., Z. Zhou, W.D. Zhang and W.Y. Chen, 2005. In vitro studies of baicalin alone or in combination with Salvia miltiorrhiza extract as a potential anti-cancer agent. Int. J. Oncol., 26: 217-224.
  287. Zhang, W., W. Zhang, T. Li, R. Liu, H. Li and H. Chen, 2004. A new flavan from Daphne odora var. atrocaulis. Fitoterapia, 75: 799-800.
    CrossRef  |  Direct Link  |  
  288. Yang, G.J., Z.B. Gu, W.Y. Liu, Y. Qiu, T.Z. Li and W.D. Zhang, 2004. Two new iridoids from Patrinia scabra. J. Asian Nat. Prod. Res., 6: 277-280.
    CrossRef  |  PubMed  |  
  289. Yang, B.H., W.D. Zhang, Z.B. Gu, T.Z. Li, C. Zhang and Y. Zhou, 2004. A new labdane diterpenoid from the bark of Larix olgensis Henry var. koreana nakai. Chinese Chem. Lett., 15: 919-920.
  290. Luo, Y., Z. Qin, Z. Hong, X. Zhang and D. Ding et al., 2004. Astragaloside IV protects against ischemic brain injury in a murine model of transient focal ischemia. Neurosci. Lett., 363: 218-223.
    CrossRef  |  Direct Link  |  
  291. Liu, W.Y., W.D. Zhang, H.S. Chen, Z.B. Gu, T.Z. Li and W.S. Chen, 2004. New triterpenoid saponins from bulbs of Bolbostemma paniculatum. Planta Med., 70: 458-464.
    CrossRef  |  
  292. Liu, W.Y., W.D. Zhang, H.S. Chen, Z.B. Gu, T.Z. Li and Yun-Zhou, 2003. Pyrrole alkaloids from Bolbostemma paniculatum. J. Asian Nat. Prod. Res., 5: 159-163.
    CrossRef  |  Direct Link  |  
  293. Liu, W.Y., W. Zhang, H.S. Chen, Z.B. Gu, T.Z. Li and W.S. Chen, 2003. Two new sterols from Bolbostemma paniculatum. Chinese Chem. Lett., 14: 1037-1040.
  294. Chen, W., Z. Tao, W. Zhang and L. Sun, 2003. A new compound from the root of Salvia przewalskii maxim. Chinese Chem. Lett., 14: 711-712.
  295. Han, G.X., L.X. Wang, Z.B. Gu and W.D. Zhang, 2002. A new bibenzyl derivative from Bletilla stritata. Chinese Chem. Lett., 13: 231-232.
    PubMed  |  
  296. Gu, Z.B., G.J. Yang, W.Y. Liu, T.Z. Li, Y. Qiu and W.D. Zhang, 2002. A new alkaloid from Patrinia scabra. Chinese Chem. Lett., 13: 957-958.
  297. Qiu, Y., Y.C. Rui and W.D. Zhang, 2001. VEGF induced hyperpermeability in bovine aortic endothelial cell and inhibitory effect of salvianolic acid B1. Acta Pharmacol. Sinca, 22: 117-120.
    Direct Link  |  
  298. Chen, W.S., W. Zhang, G.J. Yang, H.S. Chen and C.Z. Qiao, 2001. Two new glucosides from Radix Polygoni multiflori proparata. Chinese Chem. Lett., 12: 503-506.
  299. Chen, W.S., B. Li, W.D. Zhang, G.J. Yang and C.Z Qiao, 2001. A new alkaloid from the root of Isatis indigotica Fort. Chinese Chem. Lett., 12: 501-502.
  300. Zhang, W.D., H.T.B. Tam, W.S. Chen, D.Y. Kong, H.T. Li, Y.H. Wang and I. Fouraste, 2000. Two new caffeoyl conjugation from Erigeron breviscapus. J. Asian Nat. Prod. Res., 2: 283-288.
    CrossRef  |  
  301. Ha, T.B.T., C. Gerhauser, W.D. Zhang, N. Ho-Chong- Line and I. Fouraste, 2000. New lanostanoids from Ganoderma lucidum that lnduce NAD(P)H: Quinone oxidoreductase in cultured hepalclc7 murine hepatoma cells. Planta Med., 66: 681-684.