Dr. Haiyun Xu
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Dr. Haiyun Xu

Professor
School of Mental Health, Wenzhou Medical University, China

Highest Degree
Ph.D. in Neurobiology from Peking Union Medical College, China

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Biography

Dr. Haiyun Xu is currently working as Professor at Department of Anatomy and Mental Health Center, Shantou University Medical College. She obtained her PhD in Department of Anatomy from Peking Union Medical College, China in 1996. She is also working as Executive Director at University of Manitoba and member of Academic Committee of the Shantou University Medical College. Dr. Haiyun received honor includes, Laura E. Chapman Award, Saskatchewan Psychiatry Research Foundation, W.G. Dewhurst Award, Canadian College of Neuro Psychopharmacology, Molstad Trust Intramural Research Award, U of S, W.G. Dewhurst Award, CCNP, and Post Award Winner, Seroquel ISS Investigators Meeting. She is also member of editorial board in number of journals. She is also serving as reviewer of many journals. She also invited to deliver lecturers in several Institutes. She has published (47) articles in journals, (2) chapters in book, (43) presentations in conferences, and reviewer of (3) articles contributed as author/co-author.

Area of Interest:

Biomedical Sciences
100%
Neurobiology
62%
Neuroimage
90%
Neuropsychopharmacology
75%
Neuroscience
55%

Research Publications in Numbers

Books
0
Chapters
4
Articles
107
Abstracts
2

Selected Publications

  1. Zhou, Y., Z. Chen, W. Li, S. Chen, H. Xu and Z. Zhou, 2023. Impacting factors and sources of perceived stress by home-quarantined residents in Shanghai during COVID-19 epidemic. BMC Public Health, Vol. 23. 10.1186/s12889-023-15701-z.
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  2. Zheng, C., H. Liu, W. Tu, L. Lin and H. Xu, 2023. Hypercoagulable state in patients with schizophrenia: Different effects of acute and chronic antipsychotic medications. Ther. Adv. Psychopharmacol., Vol. 13. 10.1177/20451253231200257.
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  3. Yao, Z., H. Dong, J. Zhu, L. Du and Y. Luo et al., 2023. Age-related decline in hippocampal tyrosine phosphatase PTPRO is a mechanistic factor in chemotherapy-related cognitive impairment. JCI Insight, Vol. 8. 10.1172/jci.insight.166306.
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  4. Cui, Y., L. Ling, Q. Huang and H. Xu, 2023. Artesunate reverses clozapine-induced lipid metabolism disorder in BRL-3A cells by effecting AMPK pathway. Curr. Chin. Sci., 3: 194-203.
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  5. Xu, H. and F. Yang, 2022. The interplay of dopamine metabolism abnormalities and mitochondrial defects in the pathogenesis of schizophrenia. Transl. Psychiatry, Vol. 12. 10.1038/s41398-022-02233-0.
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  6. Luo, X., Z. Fang, L. Lin, H. Xu, Q. Huang and H. Zhang, 2022. Plasma complement C3 and C3a are increased in major depressive disorder independent of childhood trauma. BMC Psychiatry, Vol. 22. 10.1186/s12888-022-04410-3.
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  7. Liu, M., P. Zheng, M. Zheng, W. Zhang and F. Yang et al., 2022. Cuprizone-induced dopaminergic hyperactivity and locomotor deficit in zebrafish larvae. Brain Res., Vol. 1780. 10.1016/j.brainres.2022.147802.
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  8. Zeng, H., Z. Yu, Q. Huang and H. Xu, 2021. Attachment insecurity in rats subjected to maternal separation and early weaning: Sex differences. Front. Behav. Neurosci., Vol. 15. 10.3389/fnbeh.2021.637678.
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  9. Xu, J., F. Wu, Y. Li, F. Wang and W. Lin et al., 2021. Fibroblast growth factor 21 associating with serotonin and dopamine in the cerebrospinal fluid predicts impulsivity in healthy subjects. BMC Neurosci., Vol. 22. 10.1186/s12868-021-00676-7.
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  10. Xu, J., F. Wu, F. Wang, F. Yang and M. Liu et al., 2021. The interaction of single nucleotide polymorphisms on fibroblast growth factor 19 superfamily genes is associated with alcohol dependence-related aggression. Front. Genet., Vol. 12. 10.3389/fgene.2021.695835.
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  11. Zhao, H., X. He, G. Fan, L. Li and Q. Huang et al., 2020. COVID-19 infection outbreak increases anxiety level of general public in China: Involved mechanisms and influencing factors. J. Affective Disord., 276: 446-452.
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  12. Zeng, H., X. Zhang, W. Wang, Z. Shen and Z. Dai et al., 2020. Maternal separation with early weaning impairs neuron-glia integrity: Non-invasive evaluation and substructure demonstration. Sci. Rep., Vol. 10. 10.1038/s41598-020-76640-y.
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  13. Yang, L., Y. Su, F. Guo, H. Zhang, Y. Zhao, Q. Huang and H. Xu, 2020. Deep rTMS mitigates behavioral and neuropathologic anomalies in cuprizone-exposed mice through reducing microglial proinflammatory cytokines. Front. Integr. Neurosci. Vol. 14. 10.3389/fnint.2020.556839.
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  14. Xu, Y., Z. Fang, C. Wu, H. Xu, J. Kong, Q. Huang and H. Zhang, 2020. The long-term effects of adolescent social defeat stress on oligodendrocyte lineage cells and neuroinflammatory mediators in mice. Neuropsychiatr. Dis. Treat., 16: 1321-1330.
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  15. Luo, M., M. Deng, Z. Yu, Y. Zhang, S. Xu, S. Hu and H. Xu, 2020. Differential susceptibility and vulnerability of brain cells in C57BL/6 mouse to mitochondrial dysfunction induced by short-term cuprizone exposure. Front. Neuroanat., Vol. 14. 10.3389/fnana.2020.00030.
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  16. Li, R., Z. Dai, D. Hu, H. Zeng and Z. Fang et al., 2020. Mapping the alterations of glutamate using Glu-weighted CEST MRI in a rat model of fatigue. Front. Neurol., Vol. 11. 10.3389/fneur.2020.589128.
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  17. Li, R., J. Qu, C. Wu, Z. Fang, X. Hong and H. Xu, 2020. Demonstration of an action pathway in mouse platelets leading to prolongation of bleeding time by fluoxetine. Eur. J. Pharmacol., Vol. 883. 10.1016/j.ejphar.2020.173385.
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  18. Zeng, H.Y. and H. Xu, 2019. Advances in the study of neurobiological mechanisms underlying the increased risk for anxiety and depression in the adults with experience of early-life maternal separation. Adv. Physiol. Sci., 50: 221-225.
  19. Xu, H., 2019. Neuroinflammation and anti-inflammation treatment in psychiatric disorders. EC Psychol. Psychiatry, 8: 1079-1082.
  20. Xu, H. and X. Zhuang, 2019. Atypical antipsychotics-induced metabolic syndrome and nonalcoholic fatty liver disease: A critical review. Neuropsychiatr. Dis. Treat., 15: 2087-2099.
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  21. Zhuang, X., H. Xu, Z. Fang, C. Xu, C. Xue and X. Hong, 2018. Platelet serotonin and serotonin transporter as peripheral surrogates in depression and anxiety patients. Eur. J. Pharmacol., 834: 213-220.
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  22. Zhang, L., S. Xu, Q. Huang and H. Xu, 2018. N‐acetylcysteine attenuates the cuprizone‐induced behavioral changes and oligodendrocyte loss in male C57BL/7 mice via its anti‐inflammation actions. J. Neurosci. Res., 96: 803-816.
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  23. Zhang, J., L. Yang, Z. Fang, J. Kong, Q. Huang and H. Xu, 2018. Adenosine promotes the recovery of mice from the cuprizone-induced behavioral and morphological changes while effecting on microglia and inflammatory cytokines in the brain. J. Neuroimmune Pharmacol., 13: 412-425.
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  24. Zeng, H.Y. and H. Xu, 2018. Chemical exchange saturation transfer and its application in human brain imaging. Int. J. Biomed. Eng., 41: 443-449.
  25. Xu, H., J. He, X. Zhuang and Y. Shao, 2018. Application of Antipsychotics in Patients with Alzheimer’s Disease. In: Frontiers in Clinical Drug Research-Alzheimer Disorders, Volume 8, Atta-ur-Rahman (Ed.). Bentham Science Publishers, USA., ISBN: 978-981-14-0190-9, pp: 109-133.
  26. Huang, Y., H. Xu, W. Au, C. Xu and K. Wu, 2018. Involvement of family environmental, behavioral and social functional factors in children with attention-deficit/hyperactivity disorder. Psychol. Res. Behav. Manage., 11: 447-457.
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  27. Xu, H., 2017. Chronic administration of haloperidol and working memory: Roles of caudate putamen dopamine receptors. Curr. Neurobiol., 8: 27-33.
  28. Li, Y., R. Su, S. Xu, Q. Huang and H. Xu, 2017. Artesunate prevents rats from the clozapine-induced hepatic steatosis and elevation in plasma triglycerides. Neuropsychiatr. Dis. Treat., 13: 2477-2487.
    CrossRef  |  PubMed  |  Direct Link  |  
  29. Li, J., X. Hong and H. Xu, 2017. The comorbidity of bipolar disorder, diabetes mellitus, and autoimmune hypothyroidism in an adult woman with Turner’s syndrome: A case report. Neuropsychiatr. Dis. Treat., 13: 2425-2428.
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  30. Li, J. and H. Xu, 2017. The research progress on the heterogeneity of bipolar disorder and major depressive disorder. Adv. Psychol., 7: 978-987.
  31. Huang, Y., S. Zheng, C. Xu, K. Lin and K. Wu et al., 2017. Attention-deficit hyperactivity disorder in elementary school students in Shantou, China: Prevalence, subtypes and influencing factors. Neuropsychiatr. Dis. Treat., 13: 785-792.
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  32. Chen, K., N. Wang, J. Zhang, X. Hong, H. Xu, X. Zhao and Q. Huang, 2017. Is the Val66 M et polymorphism of the brain‐derived neurotrophic factor gene associated with panic disorder? A meta‐analysis. Asia‐Pac. Psychiatry, Vol. 9. 10.1111/appy.12228.
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  33. Zhang, H., G. Yan, H. Xu, Z. Fang and J. Zhang et al., 2016. The recovery trajectory of adolescent social defeat stress-induced behavioral, 1H-MRS metabolites and myelin changes in Balb/c mice. Sci. Rep., Vol. 6. 10.1038/srep27906.
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  34. Xu, H., H. Zhang, J. Zhang, Q. Huang, Z. Shen and R. Wu, 2016. Evaluation of neuron-glia integrity by in vivo proton magnetic resonance spectroscopy: Implications for psychiatric disorders. Neurosci. Biobehav. Rev., 71: 563-577.
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  35. Shao, Y. and H. Xu, 2016. The neuroinflammation mechanisms of schizophrenia. J. Clin. Psychiatry, 26: 282-284.
  36. Qiao, J., J. Wang, H. Wang, Y. Zhang and S. Zhu et al., 2016. Regulation of astrocyte pathology by fluoxetine prevents the deterioration of Alzheimer phenotypes in an APP/PS1 mouse model. Glia, 64: 240-254.
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  37. Li, H., H. Xu, Y. Zhang, J. Guan and J. Zhang et al., 2016. Differential neurometabolite alterations in brains of medication‐free individuals with bipolar disorder and those with unipolar depression: A two‐dimensional proton magnetic resonance spectroscopy study. Bipolar Disord., 18: 583-590.
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  38. Gao, Z.Y., P. Yang, Q.J. Huang and H.Y. Xu, 2016. The influence of dizocilpine on the reserpine-induced behavioral and neurobiological changes in rats. Neurosci. Lett., 614: 89-94.
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  39. uan, Y., G. Yan, R. Wu, Q. Huang, X.M. Li and H. Xu, 2015. The cuprizone-induced changes in 1H-MRS metabolites and oxidative parameters in C57BL/6 mouse brain: Effects of quetiapine. Neurochem. Int., 90: 185-192.
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  40. Yang, P., Z. Gao, H. Zhang, Z. Fang, C. Wu, H. Xu and Q.J. Huang, 2015. Changes in proinflammatory cytokines and white matter in chronically stressed rats. Neuropsychiatr. Dis. Treatment, 11: 597-607.
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  41. Yan, G., Y. Xuan, Z. Dai, G. Zhang, H. Xu, D. Mikulis and R. Wu, 2015. Evolution of blood-brain barrier damage associated with changes in brain metabolites following acute ischemia. NeuroReport, 26: 945-951.
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  42. Xue, C., S. Chen, Q. Lin, H. Zhou and C. Huang et al., 2015. Double encephalitis with herpes simplex virus type II and cytomegalovirus in an elder Chinese: A case report. Neuropsychiatr. Dis. Treat., 11: 2833-2836.
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  43. Xu, H., 2015. Neuroinflammation in schizophrenia focused on the pharmacological and therapeutic evidence. Pharmacologia, 6: 438-453.
  44. Xu, H. and Q. Huang, 2015. Anti-inflammatory Effects of Antipsychotics and Anti-Inflammatory Treatment Strategies in Schizophrenia. In: Antipsychotic Drugs: Classification, Pharmacology and Long-Term Health Effects, Aguilar, M.L. (Ed.)., Nova Science Publishers, New York, pp: 79-109.
  45. Shao, Y., H. Peng, Q. Huang, J. Kong and H. Xu, 2015. Quetiapine mitigates the neuroinflammation and oligodendrocyte loss in the brain of C57BL/6 mouse following cuprizone exposure for one week. Eur. J. Pharmacol., 765: 249-257.
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  46. Shao, Y., G. Yan, Y. Xuan, H. Peng, Q.J. Huang, R. Wu and H. Xu, 2015. Chronic social isolation decreases glutamate and glutamine levels and induces oxidative stress in the rat hippocampus. Behav. Brain Res., 282: 201-208.
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  47. Li, H., H. Xu, J. Zhang, Y. Zhang and C. Xu et al., 2015. Differential imbalances of brain glutamate/GABA in patients with bipolar disorder and unipolar depression. Neurosci. Biomed. Eng., 3: 116-119.
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  48. Han, J.H., H.Z. Tian, Y.Y. Lian, Y. Yu and C.B. Lu et al., 2015. Quetiapine mitigates the ethanol-induced oxidative stress in brain tissue, but not in the liver, of the rat. Neuropsychiatr. Dis. Treat., 11: 1473-1482.
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  49. Zhang, H., Y. Zhang, H. Xu, L. Wang and A. Adilijiang et al., 2014. Olanzapine ameliorates neuropathological changes and increases IGF-1 expression in frontal cortex of C57BL/6 mice exposed to cuprizone. Psychiatry Res., 216: 438-445.
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  50. Zhang, H and H. Xu, 2014. The progress in the application of rTMS for the treatment of schizo-phrenia. Transl. Med. Res., 4: 65-80.
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  51. Yan, G., Y. Xuan, Z. Dai, Z. Shen, G. Zhang, H. Xu and R. Wu, 2014. Brain metabolite changes in subcortical regions after exposure to cuprizone for 6 weeks: Potential implications for schizophrenia. Neurochem. Res., 40: 49-58.
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  52. Xuan, Y., G. Yan, H. Peng, R. Wu and H. Xum, 2014. Concurrent changes in 1H-MRS metabolites and antioxidant enzymes in the brain of C57BL/6 mouse short-termly exposed to cuprizone: Possible implications for schizophrenia. Neurochem. Int., 69: 20-27.
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  53. Wang, J., Y. Zhang, H. Xu, S. Zhu and H. Wang et al., 2014. Fluoxetine improves behavioral performance by suppressing the production of soluble β-Amyloid in APP/PS1 mice. Curr. Alzheimer Res., 11: 672-680.
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  54. Zhang, K., H. Xu, L. Cao, K. Li and Q. Huang, 2013. Interleukin-1β inhibits the differentiation of hippocampal neural precursor cells into serotonergic neurons. Brain Res., 1490: 193-201.
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  55. Zhang, H., Y. Zhang, H. Xu, L. Wang and J. Zhao et al., 2013. Locomotor activity and anxiety status, but not spatial working memory are affected in mice after brief exposure to cuprizone. Neurosci. Bull., 29: 633-641.
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  56. Xu, H., H.J. Yang and X.M. Li, 2013. Differential effects of antipsychotics on the development of rat oligodendrocyte precursor cells exposed to cuprizone. Eur. Arch. Psychiatry Clin. Neurosci. 10.1007/s00406-013-0414-3.
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  57. Xu, H. and X.M. Li, 2013. The progresses in psychiatric research and prospects for their translation. Trans. Med. Res., 3: 12-33.
  58. Fang, F., H. Zhang, Y. Zhang, H. Xu and Q. Huang et al., 2013. Antipsychotics promote the differentiation of oligodendrocyte progenitor cells by regulating oligodendrocyte lineage transcription factors 1 and 2. Life Sci., 6: 429-434.
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  59. Zhou, H., Q. Cheng, H.J. Yang and H.Y. Xu, 2012. A multi-scale Bayesian hypothesis testing approach for the analysis of prepulse inhibition test. AJMMS, 2: 80-84. 2012. A multi-scale Bayesian hypothesis testing approach for the analysis of prepulse inhibition test. AJMMS, 2: 80-84.
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  60. Zhang, Y., H. Zhang, L. Wang, W. Jiang and H. Xu et al., 2012. Quetiapine enhances oligodendrocyte regeneration and myelin repair after cuprizone-induced demyelination. Schizphr. Res., 138: 8-17.
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  61. Xu, H., H.J. Yang and G.M. Rose, 2012. Haloperidol-induced spatial memory deficits are accompanied with the upregulation of D1 and D2 receptors in the caudate putamen of C57BL/6 mouse. Life Sci., 91: 322-328.
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  62. Chen, Z., H. Ye, H. Xu, S. An, A. Jin, C. Zhou and S. Yang, 2012. Rotating magnets produce prompt analgesia effect in rats. Prog. Electromag. Res., 27: 203-217.
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  63. Zhou, H., Q. Cheng, H.J. Yang and H. Xu, 2011. Weighted kernel density estimation of the prepulse inhibition test. JCS, 7: 611-618.
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  64. Yang, H.J., K. Wang, Q. Chen and H. Xu, 2011. Abnormal behaviors and micro-structural changes in white matter of juvenile mice repeatedly exposed to amphetamine. Schizophr. Res. Treatment. 10.1155/2011/542896.
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  65. Xu, H., V. Haroutunian, G. Bartzokis and M.E. Shenton, 2011. Oligodendrocytes in schizophrenia. Schizophr. Res. Treatment. .
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  66. Xu, H., H.J. Yang, G.M. Rose and X.M. Li, 2011. Recovery of behavioral changes and compromised white matter in C57BL/6 mice exposed to cuprizone: Effects of anti-psychotic drugs. Front. Behav. Neurosci., Vol. 5. 10.3389/fnbeh.2011.00031.
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  67. Xu, H., H. Yang and G. Rose, 2011. Working Memory Deficits in Schizophrenia: Neuro-Biological Correlates and Treatment. In: Working Memory: Capacity, Developments and Improvement Techniques, Levin, E.S. (Ed.). Nova Publishers Inc., USA., pp: 313-344.
  68. Xu, H. and X.M. Li, 2011. White matter abnormalities and animal models examining a putative role of altered white matter in schizophrenia. Schizophr. Res. Treatment. 10.1155/2011/826976.
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  69. Xu, H., H.J. Yang, B. McConomy, R. Browning and X.M. Li, 2010. Behavioral and neurobiological changes in C57BL/6 mouse exposed to cuprizone: Effects of antipsychotics. Front. Behav. Neurosci., Vol. 4. 10.3389/fnbeh.2010.00008.
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  70. Wang, H., H. Xu, J. Niu, F. Mei and X.M. Li et al., 2010. Haloperidol activates quiescent oligodendroglia precursor cells in the adult mouse brain. Schizophr. Res., 119: 164-174.
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  71. Fang, S., B. Yan, D. Wang, X. Bi and Y. Zhang et al., 2010. Chronic effects of venlafaxine on synaptophysin and neuronal cell adhesion molecule in the hippocampus of cerebral ischemic mice. Biochem. Cell. Biol., 88: 655-663.
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  72. Yang, H.J., H. Wang, Y. Zhang, L. Xiao and R. Clough et al., 2009. Region-specific susceptibilities to cuprizone-induced lesions in the mouse forebrain: Implications for the pathophysiology of schizophrenia. Brain Res., 1270: 121-130.
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  73. Xu, H., H.J. Yang, Y. Zhang, R. Clough, R. Browning and X.M. Li, 2009. Behavioral and neurobiological changes in C57BL/6 mice exposed to cuprizone. Behav. Neurosci., 123: 418-429.
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  74. He, J., H. Luo, B. Yan, Y. Yu and H. Wang et al., 2009. Beneficial effects of quetiapine in a transgenic mouse model of Alzheimer's disease. Neurobiol. Aging, 30: 1205-1216.
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  75. Zhang, Y., H. Xu, W. Jiang, L. Xiao and B. Yan et al., 2008. Quetiapine alleviates the cuprizone-induced demyelination and promotes the remyelination following withdrawal of cuprizone. Schizophr. Res., 106: 182-191.
  76. Xu, H., H. Wang, L. Zhuang, B. Yan and Y. Yu et al., 2008. Demonstration of an anti-oxidative stress mechanism of quetiapine: Implications for the treatment of Alzheimer's disease. FEBS J., 275: 3718-3728.
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  77. Xiao, L., H. Xu, Y. Zhang, Z. Wei and J. He et al., 2008. Quetiapine facilitates oligodendrocyte development and prevents mice from myelin breakdown and behavioral changes. Mol. Psychiatry, 13: 697-708.
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  78. Zhang, Y., H. Xu, J. He, B. Yan, W. Jiang and X.M. Li, 2007. Quetiapine reverses altered locomotor activity and tyrosine hydroxylase immunoreactivity in rat caudate putamen following long-term haloperidol treatment. Neurosci. Lett., 420: 66-71.
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  79. Yan, B., X. Bi, J. He, Y. Zhang and S. Thakur et al., 2007. Quetiapine attenuates spatial memory impairment and hippocampal neurodegeneration induced by bilateral common carotid artery occulusion in mice. Life Sci., 81: 353-361.
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  80. Yan, B., J. He, H. Xu, Y. Zhang and X. Bi et al., 2007. Quetiapine attenuates the depressive and anxiolytic-like behavioural changes induced by global cerebral ischemia in mice. Behav. Brain Res., 182: 36-41.
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  81. Xu, H. and X.M. Li, 2007. Cellular Metabolism. In: Psychiatric and Metabolic Disorders: Research Synthesis and Clinical Translation, McIntyre and Konarski (Eds.). Nova Publishers Inc., USA., pp: 57-73.
  82. Li, X.M. and H. Xu, 2007. In vitro and in vivo evidence for neuroprotective effects of antipsychotic drugs: Implications for the pathophysiology and treatment of schizophrenia. Int. Rev. Neurobiol., 77: 107-142.
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  83. Xu, H., Z. Chen, J. He, S. Haimanot and X.M. Li, 2006. Quetiapine and venlafaxine share common actions on the hippocampal formation in rats exposed to chronic restraint stress. Hippocampus, 16: 551-559.
  84. He, J., H. Xu, Y. Yang, D. Rajakumar, X. Li and X.M. Li, 2006. The effects of chronic administration of quetiapine on the phencyclidine-induced reference memory impairment and decrease of Bcl-XL/Bax ratio in the posterior cingulate cortex in rats. Behav. Brain Res., 168: 236-242.
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  85. Bai, O., H. Xu and X.M. Li, 2006. Haloperidol and atypical antipsychotics share a same action of decreasing p75NTR mRNA levels in PC12 cells. Life Sci., 79: 570-574.
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  86. Wang, H., H. Xu, L. Dyck and X.M. Li, 2005. Atypical antipsychotics protect PC12 cells against amyloid-induced apoptosis by inhibiting oxidative stress. J. Neurosci. Res., 81: 572-580.
  87. Luo, C., H. Xu and X.M. Li, 2005. Quetiapine reverses the suppression of hippocampal neurogenesis caused by repeated restraint stress. Brain Res., 1063: 32-39.
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  88. He, J., Y. Yang, H. Xu, X. Zhang and X.M. Li, 2005. Olanzapine attenuates the okadaic acid-induced spatial memory impairment and hippocampal cell death in rats. Neuropsychopharmacology, 30: 1511-1520.
    PubMed  |  
  89. He, J., H. Xu, Y. Yang, X. Zhang and X.M. Li, 2005. Chronic administration of quetiapine alleviates the anxiety-like behavioural changes induced by neurotoxic regimen of dl-amphetamine in rats. Behav. Brain Res., 160: 178-187.
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  90. Chen, Z., H. Xu, S. Haimanot, X. Li and X.M. Li, 2005. Quetiapine and venlafaxine synergically regulate heme oxygenase-2 protein expression in hippocampal formations of stressed rats. Neurosci. Lett., 389: 173-177.
  91. Xu, H., J.S. Richardson, C. Luo and X.M. Li, 2004. Recovery of hippocampal cell proliferation and BDNF levels, both of which are reduced by repeated restraint stress, is accelerated by chronic venlafaxine. Pharmacogenomics J., 4: 322-331.
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  92. Xu, H., J. He, J.S. Richardson and X.M. Li, 2004. The response of synaptophysin and microtubule-associated protein 1 to restraint stress in rat hippocampus and its modulation by venlafaxine. J. Neurochem., 91: 1380-1388.
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  93. Luo, C., H. Xu and X.M. Li, 2004. Post-stress changes in BDNF and Bcl-2 immuno-reactivities in hippocampal neurons: Effect of chronic administration of olanzapine. Brain Res., 1025: 194-202.
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  94. He, J., H. Xu, Y. Yang, X. Zhang and X.M. Li, 2004. Neuroprotective effects of olanzapine on methamphetamine-induced neurotoxicity are associated with an inhibition of hyperthermia and prevention of Bcl-2 decrease in rats. Brain Res., 1018: 186-192.
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  95. Xu, H., J.S. Richardson and X.M. Li, 2003. Dose-related effects of chronic antidepressants on the neuroprotective proteins BDNF, Bcl-2 and Cu/Zn-SOD in rat hippocampus. Neuropsychopharmacology, 28: 53-62.
    PubMed  |  
  96. Qing, H., H. Xu, Z. Wei, D. Gibson and X.M. Li, 2003. The ability of atypical antipsychotic drugs vs. haloperidol to protect PC12 cells against MPP+ -induced apoptosis. Eur. J. Neurosci., 17: 1563-1570.
  97. Xu, H., H. Qing, W. Lu, D. Keegan, J.S. Richardson, J. Chlan-Fourney and X.M. Li, 2002. Quetiapine attenuates the immobiliza-tion stress-induced decrease of brain-derived neurotrophic factor expression in rat hippocampus. Neurosci. Lett., 321: 65-68.
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  98. Xu, H., S.J. Li, J. Bodurka, X. Zhao, Z.X. Xi and E.A. Stein, 2000. Heroin-induced neuronal activation in rat brain: Assessed by functional MRI. Neuroreport, 11: 1085-1092.
    PubMed  |  
  99. Bodurka, J., A. Jesmanowicz, J.S. Hyde, H. Xu, L. Estkowski and S.J. Li, 1999. Current-induced magnetic resonance phase imaging. J. Magnetic Resonance, 137: 265-271.
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  100. Wong-Riley, M., Z. Huang, W. Liebl, H. Xu and C. Zhang, 1998. Neurochemical organization of the macaque retina: Effect of TTX on levels and gene expression of cytochrome oxidase and nitric oxide synthase and on the immnoreactivity of Na+K+ ATPase and NMDA receptor subunit I. Vision Res., 38: 1455-1477.