Dr. Xiaojun Liu
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Dr. Xiaojun Liu

Instructor
Department of Medicine, Mass General Hospital


Highest Degree
Ph.D. in Genetics from Fudan University, Shanghai, China

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Area of Interest:

Molecular Sciences
100%
Molecular Biology
62%
MicroRNA (miRNA)
90%
Cardiovascular Disease
75%
Proliferation
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
46
Abstracts
0

Selected Publications

  1. Liu, X., Y. Cheng, S. Zhang, Y. Lin, J. Yang and C. Zhang, 2009. A necessary role of miR-221 and miR-222 in vascular smooth muscle cell proliferation and neointimal hyperplasia. Circ Res., 104: 476-487.
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  2. Liu, X., Y. Cheng, J. Yang and C. Zhang, 2009. Upregulation of miR-221 and miR-222 in diabetic vessel after angioplasty. Proceedings of the 2009 Annual Meeting of the American Society Anesthesiologists, Oct. 17-21, American Society of Anesthesiologists, New Orleans, LA., pp: 92-110.
    Direct Link  |  
  3. Lin, Y., X. Liu, Y. Cheng, J. Yang, Y. Huo and C. Zhang, 2009. Involvement of MicroRNAs in hydrogen peroxide-mediated gene regulation and cellular injury response in vascular smooth muscle cells. J. Biol. Chem., 284: 7903-7913.
    CrossRef  |  PubMed  |  Direct Link  |  
  4. Dong, S., Y. Cheng, J. Yang, J. Li and X. Liu et al., 2009. MicroRNA expression signature and the role of microRNA-21 in the early phase of acute myocardial infarction. J. Biol. Chem., 284: 29514-29525.
    CrossRef  |  PubMed  |  Direct Link  |  
  5. Cheng, Y., X. Liu, S. Zhang, Y. Lin, J. Yang and C. Zhang, 2009. MicroRNA-21 protects against the H2O2-induced injury on cardiac myocytes via its target gene PDCD4. J. Mol. Cell. Cardiol., 47: 5-14.
    CrossRef  |  PubMed  |  Direct Link  |  
  6. Cheng, Y., X. Liu, J. Yang, Y. Lin and D. Xu et al., 2009. MicroRNA-145, a novel smooth muscle cell phenotypic marker and modulator, controls vascular neointimal lesion formation. Circ Res., 105: 158-166.
    CrossRef  |  PubMed  |  Direct Link  |  
  7. Cheng, Y., X. Liu, J. Yang and C. Zhang, 2008. The Effects of Some MicroRNAs in vascular neointimal formation may depend on cell cycle phase. Circ. Res., 102: 102-102.
    Direct Link  |  
  8. Sun, X., X. Liu, B. Huang, W. Li, X. Wang, J. Lin and K. Tang, 2007. Cloning and analysis of a novel conserved membrane zinc-metalloprotease family from Solanum surattense. Russ. J. Plant Physiol., 54: 63-73.
    CrossRef  |  Direct Link  |  
  9. Lin, J., X. Zhou, S. Gao, X. Liu, W. Wu, X. Sun and K. Tang, 2007. cDNA cloning and expression analysis of a mannose-binding lectin from Pinellia pedatisecta. J. Biosci., 32: 241-249.
    CrossRef  |  PubMed  |  Direct Link  |  
  10. Ji, R., Y. Cheng, J. Yue, J. Yang and X. Liu et al., 2007. MicroRNA expression signature and antisense-mediated depletion reveal an essential role of microRNA in vascular neointimal lesion formation. Circ. Res., 100: 1579-1588.
    CrossRef  |  PubMed  |  Direct Link  |  
  11. Cheng, Y., R. Ji, J. Yue, J. Yang and X. Liu et al., 2007. MicroRNAs are aberrantly expressed in hypertrophic heart: Do they play a role in cardiac hypertrophy?. Am. J. Pathol., 170: 1831-1840.
    CrossRef  |  PubMed  |  Direct Link  |  
  12. Liu, X., B. Huang, J. Lin, J. Fei and Z. Chen et al., 2006. A novel pathogenesis-related protein (SsPR10) from Solanum surattense with ribonucleolytic and antimicrobial activity is stress- and pathogen-inducible J. Plant Physiol., 163: 546-556.
    CrossRef  |  PubMed  |  Direct Link  |  
  13. Lin, J., X. Zhou, S. Gao, W. Wu, X. Liu, X. Sun and K. Tang, 2006. Authentication of pinellia ternata and its adulterants based on PCR with specific primers. Planta Med., 72: 844-847.
    PubMed  |  
  14. Wang, X., X. Sun, S. Liu, L. Liu, X. Liu, X. Sun and K. Tang, 2005. Molecular cloning and characterization of a novel ice gene from Capsella bursa-pastoris. Mol. Biol., 39: 18-25.
    CrossRef  |  PubMed  |  Direct Link  |  
  15. Huang, B., X. Liu, X. Wang, Y. Pi and J. Lin et al., 2005. Isolation and expression profiling of the Pto-like gene SsPto from Solanum surattense. Mol. Biol., 39: 684-695.
    CrossRef  |  PubMed  |  Direct Link  |  
  16. Huang, B., X. Liu, X. Wang, Y. Pi and J. Lin et al., 2005. Genomic cloning and characterization of a Pto-like gene SsPto-2 from Solanum surattense. DNA Seq., 16: 277-287.
    PubMed  |  Direct Link  |  
  17. Deng, Z., Y. Pang, W. Kong, Z. Chen and X. Wang et al., 2005. A novel ABA-dependent dehydrin ERD10 gene from Brassica napus. DNA Seq., 16: 28-35.
    PubMed  |  Direct Link  |  
  18. Chen, Z., G. Kai, X. Liu, J. Lin, X. Sun and K. Tang, 2005. cDNA cloning and characterization of a mannose-binding lectin from Zingiber officinale Roscoe (ginger) rhizomes. J. Biosci., 30: 213-220.
    CrossRef  |  PubMed  |  Direct Link  |  
  19. Chen Z, Y. Pang, X. Liu, X. Wang, Z. Deng, X. Sun and K. Tang, 2005. Molecular cloning and characterization of a novel mannose-binding lectin cDNA from Zantedeschia aethiopica. Biocell, 29: 187-193.
    PubMed  |  Direct Link  |  
  20. Wang, X., S. Liu, X. Liu, Z. Chen and X. Liu et al., 2004. Molecular cloning and characterization of a CBF gene from Capsella bursa-pastoris. DNA Seq., 15: 180-187.
    PubMed  |  
  21. Pang, Y., G. Shen, C. Liu, X. Liu, F. Tan, X. Sun and K. Tang, 2004. Molecular cloning and sequence analysis of a novel chalcone synthase cDNA from Ginkgo biloba. J. DNA Mapping Seq. Analysis, 15: 283-290.
    PubMed  |  Direct Link  |  
  22. Liu, X., Y. Deng, H. Gao, X. Gou, J. Wu, W. Guo and X. Li, 2002. Molecular cloning and characterizing of EPSPs cene3' end from Orychrophragmus violaceus. J. Sichuan Univ., 39: 1152-1154.
    Direct Link  |  
  23. Liu, X., Y. Deng, D. You and X. Li, 2002. The cDNA nucleotide sequence of EPSPs gene from Orychophragmus violaceus. J. Plant Physiol. Mol. Biol., 28: 323-324.
    Direct Link  |  
  24. Li, X., J. Wu, L. Li, S. Wu and X. Liu, 2000. Production of the intergeneric hybrid of Brassica napus ogucms and Orychophragmus violaceus. J. Sichuan Univ., 37: 257-260.