Area of Interest:

Pharmacology and Toxicology

100%

Immunopharmacology

62%

Neuroinflammation

90%

Clinical Research

75%

Medicinal Chemistry

55%

Research Publications in Numbers

Books
0

Chapters
0

Articles
0

Abstracts
0

Selected Publications

Zhou, M., H. Li, L. Huang, X. Huang and F. Liu et al., 2017. Dihydroartemisinin modulation of toll-like receptors-4 signaling pathway in lipopolysaccharide-stimulated RAW264. 7 murine macrophages. Int. J. Clin. Exp. Pathol., 10: 5530-5537.
Direct Link |
Lin, K., S. Fang, B. Cai, X. Huang and X. Zhang et al., 2014. ERK/Egr-1 signaling pathway is involved in CysLT 2 receptor-mediated IL-8 production in HEK293 cells. Eur. J. Cell Biol., 93: 278-288.
CrossRef | Direct Link |
Huang, X., Z. Xie, F. Liu, C. Han and D. Zhang et al., 2014. Dihydroartemisinin inhibits activation of the Toll-like receptor 4 signaling pathway and production of type I interferon in spleen cells from lupus-prone MRL/lpr mice. Int. Immunopharmacol., 221: 266-272.
CrossRef | Direct Link |
Dong, X.,Y. Zhao, X. Huang, K. Lin and J. Chen et al., 2013. Structure-based drug design using GPCR homology modeling: toward the discovery of novel selective CysLT2 antagonists. Eur. J. Med. Chem., 62: 754-763.
CrossRef | Direct Link |
Zhao, B., C.Z. Zhao, X.Y. Zhang, X.Q. Huang and W.Z. Shi et al., 2012. The new P2Y-like receptor G protein-coupled receptor 17 mediates acute neuronal injury and late microgliosis after focal cerebral ischemia in rats. Neuroscience, 202: 42-57.
CrossRef | Direct Link |
Wei, E.Q., K.N. Lin, S.H. Fang, W.P. Zhang, X.Q. Huang and Y.B. Lu, 2012. Nuclear translocation of cysteinyl leukotriene receptor 1 is involved in oxygen-glucose deprivation-induced damage to endothelial cells. Acta Pharmacol. Sinica, 33: 1511-1517.
CrossRef | Direct Link |
Huang, X.Q., X.Y. Zhang, X.R. Wang, S.Y. Yu and S.H. Fang et al., 2012. Transforming growth factor β1-induced astrocyte migration is mediated in part by activating 5-lipoxygenase and cysteinyl leukotriene receptor. J. Neuroinflammation., Vol. 9. 10.1186/1742-2094-9-145.
CrossRef | Direct Link |
Zhao, R., S.H. Fang, K.N. Lin, X.Q. Huang, Y.B. Lu, W.P. Zhang and E.Q. Wei, 2011. Pranlukast attenuates hydrogen peroxide-induced necrosis in endothelial cells by inhibiting oxygen reactive species-mediated collapse of mitochondrial membrane potential. J. Cardiovasc. Pharmacol., 57: 479-488.
CrossRef | Direct Link |
Dong, X., L. Wang, X. Huang, T. Liu and E. Wei et al., 2010. Pharmacophore identification, synthesis, and biological evaluation of carboxylated chalcone derivatives as CysLT 1 antagonists. Bioorg. Med. Chem., 18: 5519-5527.
CrossRef | Direct Link |