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Xiukun Lin

Xiukun Lin

LiveDNA ID: 86.17076
ACSE
47 Publications
1 Editorial Roles
0 Projects

Education

Academic Background
  • Ph.D. Peking Union Medical College, China Pharmacology | Completed: 1996

Editorial Services

Editorial & Publishing Roles
Science International
Editorial Board Member
Jun 2019 — Present

Serving as Editorial Board Member for Science International.

Publications (47)

Selected Scholarly Contributions
Aqueous extract of clove inhibits tumor growth by inducing autophagy through AMPK/ULK pathway
Cong Li, Huanli Xu, Xiaoliang Chen, Jijun Chen, Xiao Li, Gan Qiao, Ye Tian, Ru Yuan, Shuonan Su, Xiaohui Liu, Xiukun Lin
Phytotherapy Research | Journal Article
10.1002/ptr.6367
Crossref
2019
Maslinic acid induces autophagy by down‐regulating HSPA8 in pancreatic cancer cells
Ye Tian, Huanli Xu, Ammad Ahmad Farooq, Baozeng Nie, Xiaoliang Chen, Shuonan Su, Ru Yuan, Gan Qiao, Cong Li, Xiao Li, Xiaohui Liu, Xiukun Lin
Phytotherapy Research | Journal Article
10.1002/ptr.6064
Crossref
2018
Luteolin synergizes the antitumor effects of 5-fluorouracil against human hepatocellular carcinoma cells through apoptosis induction and metabolism.
Xu, H., T. Yang, X. Liu, Y. Tian and X. Chen et al.,
Life Sci., | Journal Article
10.1016/j.lfs.2015.12.002
Self Xiukun Lin
2016
Prostate cancer stem cells: Viewing signaling cascades at a finer resolution.
Lin, X., A.A. Farooqi, M.Z. Qureshi, M.A. Romero, S. Tabassum and M. Ismail,
Arch. Immunol. Ther. Exp., | Journal Article
10.1007/s00005-016-0383-0
Self Xiukun Lin
2016
In vitro studies of polyethyleneimine coated miRNA microspheres as anticancer agents.
Rytblat, I., N. Wu, H. Xu, A. Gedanken and X. Lin,
Nano Res., | Journal Article
10.1007/s12274-016-1055-4
Self Xiukun Lin
2016
Zinc-doped copper oxide nanocomposites inhibit the growth of human cancer cells through reactive oxygen species-mediated NF-κB activations.
Yuan, R., H. Xu, X. Liu, Y. Tian and C. Li et al.,
ACS Applied Mater. Interfaces, | Journal Article
10.1021/acsami.6b09542
Self Xiukun Lin
2016
Cloning, expression and cytotoxicity of granulin A, a novel polypeptide contained in human progranulin.
Wang, X., H. Xu, X. Chen, Y. Tian, F. Wang and X. Lin,
Biosci. Trends, | Journal Article
10.5582/bst.2016.01036
Self Xiukun Lin
2016
Cytotoxicity of the compounds isolated from Pulsatilla chinensis saponins and apoptosis induced by 23-hydroxybetulinic acid.
Liu, M., X. Zhao, L. Xiao, G. Liu and H. Liu et al.,
Pharm. Biol., | Journal Article
10.3109/13880209.2014.907323
Self Xiukun Lin
2015
Recent progress in fungus-derived bioactive agents for targeting of signaling machinery in cancer cells.
Lin, X., A.A. Farooqi and M. Ismail,
Drug Des. Dev. Ther., | Journal Article
10.2147/DDDT.S77341
Self Xiukun Lin
2015
Antitumor effects of traditional Chinese medicine targeting the cellular apoptotic pathway.
Xu, H., X. Zhao, X. Liu, P. Xu, K. Zhang and X. Lin,
Drug Des. Dev. Ther., | Journal Article
10.2147/DDDT.S80902
Self Xiukun Lin
2015
Cardamonin induces apoptosis by suppressing STAT3 signaling pathway in glioblastoma stem cells.
Wu, N., J. Liu, X. Zhao, Z. Yan and B. Jiang et al.,
Tumor Biol., | Journal Article
10.1007/s13277-015-3673-y
Self Xiukun Lin
2015
Marine bromophenol bis (2,3-dibromo-4,5-dihydroxybenzyl) ether, represses angiogenesis in HUVEC cells and in zebrafish embryos via inhibiting the VEGF signal systems.
Qi, X., G. Liu, L. Qiu, X. Lin and M. Liu,
Biomed. Pharmacother., | Journal Article
10.1016/j.biopha.2015.08.033
Self Xiukun Lin
2015
Bis(2,3-dibromo-4,5-dihydroxybenzyl) ether, a marine algae derived bromophenol, inhibits the growth of Botrytis cinerea and interacts with DNA molecules.
Liu, M., G. Wang, L. Xiao, X. Xu, X. Liu, P. Xu and X. Lin,
Mar. Drugs, | Journal Article
10.3390/md12073838
Self Xiukun Lin
2014
Oleanolic acid induces protective autophagy in cancer cells through the JNK and mTOR pathways.
Liu, J., L. Zheng, J. Zhong, N. Wu, G. Liu and X. Lin,
Oncol. Rep., | Journal Article
Self Xiukun Lin
2014
Oleanolic acid induces metabolic adaptation in cancer cells by activating the AMP-activated protein kinase pathway.
Liu, J., L. Zheng, N. Wu, L. Ma, J. Zhong, G. Liu and X. Lin,
J. Agric. Food Chem., | Journal Article
10.1021/jf500622p
Self Xiukun Lin
2014
CS5931, a novel polypeptide in Ciona savignyi, represses angiogenesis via inhibiting vascular endothelial growth factor (VEGF) and matrix metalloproteinases (MMPs).
Liu, G., M. Liu, J. Wei and X. Lin,
Mar. Drugs, | Journal Article
10.3390/md12031530
Self Xiukun Lin
2014
Oleanolic acid inhibits proliferation and invasiveness of Kras-transformed cells via autophagy.
Liu, J., L. Zheng, L. Ma, B. Wang and Y. Zhao et al.,
J. Nutr. Biochem., | Journal Article
10.1016/j.jnutbio.2014.06.006
Self Xiukun Lin
2014
Clove extract inhibits tumor growth and promotes cell cycle arrest and apoptosis.
Liu, H., J.C. Schmitz, J. Wei, S. Cao and J.H. Beumer et al.,
Oncol. Res. Featuring Preclin. Clin. Cancer Ther., | Journal Article
10.3727/096504014X13946388748910
Self Xiukun Lin
2014
Aplysin sensitizes cancer cells to TRAIL by suppressing P38 MAPK/survivin pathway.
Liu, J., L. Ma, N. Wu, G. Liu, L. Zheng and X. Lin,
Mar. Drugs, | Journal Article
10.3390/md12095072
Self Xiukun Lin
2014
Characterization of the high cytochalasin E and rosellichalasin producing-Aspergillus sp. nov. F1 isolated from marine solar saltern in China.
Xiao, L., H. Liu, N. Wu, M. Liu, J. Wei, Y. Zhang and X. Lin,
World J. Microbiol. Biotechnol., | Journal Article
10.1007/s11274-012-1152-9
Self Xiukun Lin
2013
Mere15, a novel polypeptide from Meretrix meretrix, inhibits adhesion, migration and invasion of human lung cancer A549 cells via down-regulating MMPs.
Wang, H., J. Wei, N. Wu, M. Liu and C. Wang et al.,
Pharm. Biol., | Journal Article
10.3109/13880209.2012.715169
Self Xiukun Lin
2013
Identification of Streptomyces sp. nov. WH26 producing cytotoxic compounds isolated from marine solar saltern in China.
Liu, H., L. Xiao, J. Wei, J.C. Schmitz and M. Liu et al.,
World J. Microbiol. Biotechnol., | Journal Article
10.1007/s11274-013-1290-8
Self Xiukun Lin
2013
Targeting cellular apoptotic pathway with peptides from marine organisms.
Zheng, L., X. Lin, N. Wu, M. Liu and Y. Zheng et al.,
Biochim. Biophys. Acta (BBA)-Rev. Cancer, | Journal Article
10.1016/j.bbcan.2013.02.006
Self Xiukun Lin
2013
Cloning, characterization and expression of a cDNA encoding a granulin-like polypeptide in Ciona savignyi.
Zhao, J., J. Wei, M. Liu, L. Xiao and N. Wu et al.,
Biochimie, | Journal Article
10.1016/j.biochi.2013.05.001
Self Xiukun Lin
2013
MiR-125b acts as an oncogene in glioblastoma cells and inhibits cell apoptosis through p53 and p38MAPK-independent pathways.
Wu, N., X. Lin, X. Zhao, L. Zheng and L. Xiao et al.,
Br. J. Cancer, | Journal Article
10.1038/bjc.2013.672
Self Xiukun Lin
2013
A novel polypeptide extracted from Ciona savignyi induces apoptosis through a mitochondrial-mediated pathway in human colorectal carcinoma cells.
Cheng, L., C. Wang, H. Liu, F. Wang and L. Zheng et al.,
Clin. Colorectal Cancer, | Journal Article
10.1016/j.clcc.2012.01.002
Self Xiukun Lin
2012
Silencing myostatin gene by RNAi in sheep embryos.
Tang, D., H. Zhu, J. Wu, H. Chen and Y. Zhang et al.,
J. Biotechnol., | Journal Article
10.1016/j.jbiotec.2012.01.008
Self Xiukun Lin
2012
Marine bromophenol bis (2,3-dibromo-4,5-dihydroxybenzyl) ether, induces mitochondrial apoptosis in K562 cells and inhibits topoisomerase I in vitro.
Liu, M., W. Zhang, J. Wei, L. Qiu and X. Lin,
Toxicol. Lett., | Journal Article
10.1016/j.toxlet.2012.03.771
Self Xiukun Lin
2012
A novel polypeptide from Meretrix meretrix Linnaeus inhibits the growth of human lung adenocarcinoma.
Wang, C., M. Liu, L. Cheng, J. Wei, N. Wu, L. Zheng and X. Lin,
Exp. Biol. Med., | Journal Article
10.1258/ebm.2012.011337
Self Xiukun Lin
2012
Zebrafish p53 protein enhances the translation of its own mRNA in response to UV irradiation and CPT treatment.
Zhao, X., N. Wu, L. Ding, M. Liu, H. Liu and X. Lin,
FEBS Lett., | Journal Article
10.1016/j.febslet.2012.03.025
Self Xiukun Lin
2012
miR-125b regulates the proliferation of glioblastoma stem cells by targeting E2F2.
Wu, N., L. Xiao, X. Zhao, J. Zhao and J. Wang et al.,
FEBS Lett., | Journal Article
10.1016/j.febslet.2012.08.023
Self Xiukun Lin
2012
Induction of apoptosis, G0/G1 phase arrest and microtubule disassembly in K562 leukemia cells by Mere15, a novel polypeptide from Meretrix meretrix Linnaeus.
Liu, M., X. Zhao, J. Zhao, L. Xiao and H. Liu et al.,
Mar. Drugs, | Journal Article
10.3390/md10112596
Self Xiukun Lin
2012
Oleanolic acid potentiates the antitumor activity of 5-fluorouracil in pancreatic cancer cells.
Wei, J., H. Liu, M. Liu, N. Wu and J. Zhao et al.,
Oncol. Rep., | Journal Article
10.3892/or.2012.1921
Self Xiukun Lin
2012
Cytotoxic metabolites from the soil-derived fungus Exophiala pisciphila.
Wang, C.C., H.Z. Liu, M. Liu, Y.Y. Zhang, T.T. Li and X.K. Lin,
Molecules, | Journal Article
10.3390/molecules16042796
Self Xiukun Lin
2011
Synthesis and α-glucosidase inhibitory mechanisms of bis (2,3-dibromo-4,5-dihydroxybenzyl) ether, a potential marine bromophenol α-glucosidase inhibitor.
Liu, M., W. Zhang, J. Wei and X. Lin,
Mar. Drugs, | Journal Article
10.3390/md9091554
Self Xiukun Lin
2011
Bromophenols in marine algae and their bioactivities.
Liu, M., P.E. Hansen and X. Lin,
Mar. Drugs, | Journal Article
10.3390/md9071273
Self Xiukun Lin
2011
Phylogenetic analysis and screening of antimicrobial and cytotoxic activities of moderately halophilic bacteria isolated from the Weihai Solar Saltern (China).
Chen, L., G. Wang, T. Bu, Y. Zhang, Y. Wang, M. Liu and X. Lin,
World J. Microbiol. Biotechnol., | Journal Article
10.1007/s11274-009-0247-4
Self Xiukun Lin
2010
α-glucosidase inhibition and the in vivo hypoglycemic effect of butyl-isobutyl-phthalate derived from the Laminaria japonica rhizoid.
Bu, T., M. Liu, L. Zheng, Y. Guo and X. Lin,
Phytother. Res., | Journal Article
10.1002/ptr.3139
Self Xiukun Lin
2010
Recovery of recombinant zebrafish p53 protein from inclusion bodies and its binding activity to p53 mRNA in vitro.
Zhao, X., M. Liu, N. Wu, L. Ding, H. Liu and X. Lin,
Protein Expression Purif., | Journal Article
10.1016/j.pep.2010.03.028
Self Xiukun Lin
2010
Targeting cellular proapoptotic molecules for developing anticancer agents from marine sources.
Lin, X., M. Liu, C. Hu and D.J. Liao,
Curr. Drug Targets, | Journal Article
10.2174/138945010791170824
Self Xiukun Lin
2010
Synthesis of butyl-isobutyl-phthalate and its interaction with α-glucosidase in vitro.
Liu, M., W. Zhang, L. Qiu and X. Lin,
J. Biochem., | Journal Article
10.1093/jb/mvq110
Self Xiukun Lin
2010
VEGF gene silencing by cytomegalovirus promoter driven ShRNA expression vector results in vascular development defects in Zebrafish.
Yang, S.L., S. Yan, R.L. Niu and X. Lin,
Russian J. Genet., | Journal Article
10.1134/S1022795409090038
Self Xiukun Lin
2009
A novel anti-tumor protein extracted from Meretrix meretrix Linnaeus induces cell death by increasing cell permeability and inhibiting tubulin polymerization.
Ning, X., J. Zhao, Y. Zhang, S. Cao, M. Liu, P. Ling and X. Lin,
Int. J. Oncol., | Journal Article
10.3892/ijo_00000393
Self Xiukun Lin
2009
Aberrant expression of X-linked genes RbAp46, Rsk4 and Cldn2 in breast cancer.
Thakur, A., K. Rahman, J. Wu, X. Lin and H. Nassar et al.,
Mol. Cancer Res., | Journal Article
Self Xiukun Lin
2007
N-acetylchitooligosaccharide is a potent angiogenic inhibitor both in vivo and in vitro.
Wang, Z., L.H. Zheng, S.L. Yang, R.L. Niu, E. Chu and X. Lin,
Biochem. Biophys. Res. Commun., | Journal Article
10.1016/j.bbrc.2007.03.094
Self Xiukun Lin
2007
A novel peptide from shark cartilage with potent antiangiogenesis activity.
Zheng, L., Z. Wang, R.L. Niu, C.X. Hu and X. Lin,
Cancer Biol. Ther., | Journal Article
Self Xiukun Lin
2007
Sequence analysis and functional study of thymidylate synthase from zebrafish, Danio rerio.
Du, C., R. Niu, E. Chu, P. Zhang and X. Lin,
J. Biochem., | Journal Article
10.1093/jb/mvj100
Self Xiukun Lin
2006