About
Professional SummaryDr. Martinez obtained his BSc degree in Chemistry and in 1977 his MSc in Organic Chemistry, both from the School of Chemistry, National University of Mexico, he then joined the Institute of Chemistry as Researcher. He obtained a PhD in Organic Chemistry by the Center of Research and Advanced Studies, National Polytechnic Institute. At present he is Full Researcher and member of the SNI.
Education
Academic Background-
Ph.D. National University of Mexico, Mexico QUÍMICA | Completed: 1987
Publications (43)
Selected Scholarly Contributions
2026
Rational design of indolyl acrylamides as antibacterial agents targeting multidrug-resistant
Acinetobacter baumannii
strains
2025
2023
(2Z)-3-hydroxy-3-(4-R-phenyl)-prop-2-enedithioic acids as new antituberculosis compounds.
Roberto Martinez
2021
Total syntheses and antiproliferative activities of prenostodione and its analogues.
Roberto Martinez
2021
Synthesis and antituberculosis activity of new acylthiosemicarbazides designed by structural modification
2020
Synthesis of novel pyrroloazepinones by schmidt expansions of 6-indolones.
Roberto Martinez
2020
Bisindole caulerpin analogues as nature-inspired photoresponsive molecules.
Roberto Martinez
2020
Synthesis and antitubercular activity of new N-[5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl]-(nitroheteroaryl)carboxamides.
Roberto Martinez
2019
5,6-dihydropyrrolo[2,1-a]isoquinolines as alternative of new drugs with cytotoxic activity.
Roberto Martinez
2017
Antinociceptive activity of ent-dihydrotucumanoic acid isolated from Gymnosperma glutinosum Spreng less.
Roberto Martinez
2017
Pharmacological evaluation of 2-angeloyl ent-dihydrotucumanoic acid.
Roberto Martinez
2017
Synthesis and anti-tuberculosis activity of the marine natural product caulerpin and its analogues.
Roberto Martinez
2014
Synthesis of the pentacyclic framework of the alkaloid tronocarpine.
Roberto Martinez
2014
Novel TASK channels inhibitors derived from dihydropyrrolo[2,1-a]isoquinoline.
Roberto Martinez
2014
De novo design of non-coordinating indolones as potential inhibitors for lanosterol 14-α-demethylase (CYP51).
Roberto Martinez
2014
Dibenzo[1,2,5]thiadiazepines are non-competitive GABAA receptor antagonists.
Roberto Martinez
2013
Synthesis and structural characterization of cobalt(II) and copper(II) complexes with N,N-disubstituted-N′-acylthioureas.
Roberto Martinez
2012
Design and synthesis of anti-MRSA benzimidazolylbenzene-sulfonamides. QSAR studies for prediction of antibacterial activity.
Roberto Martinez
2011
Synthesis, characterization and crystal structure of Ni(II) and Cu(II) complexes with N-furoyl-N′,N′-diethylthiourea: Antifungal activity.
Roberto Martinez
2011
2010
On the selective methylation of benzoyl and furoylthiocarbamates.
Roberto Martinez
2010
Synthesis of 5,6-dihydropyrrolo[2,1-a]isoquinolines featuring an intramolecular radical-oxidative cyclization of polysubstituted pyrroles and evaluation of their cytotoxic activity.
Roberto Martinez
2010
Synthesis and cytotoxic activity of new azepino[3′,4′:4,5]pyrrolo[2,1-a]isoquinolin-12-ones.
Roberto Martinez
2009
2009
Synthesis of azepino[4,5-b]indolones via an intermolecular radical oxidative substitution of N-Boc tryptamine.
Roberto Martinez
2009
Synthesis and cytotoxic evaluation of new (4,5,6,7-tetrahydro-indol-1-yl)-3-R-propionic acids and propionic acid ethyl esters generated by molecular mimicry.
Roberto Martinez
2007
Tetrahydropyrrolo[3,2-c]azepin-4-ones as a new class of cytotoxic compounds.
Roberto Martinez
2006
The search of DNA-intercalators as antitumoral drugs: What it worked and what did not work.
Roberto Martinez
2005
Efficient, “Tin-Free” radical cyclization to aromatic systems. Synthesis of 5,6,8,9,10,11-hexahydroindolo[2,1-a]isoquinolines.
Roberto Martinez
2004
An efficient synthesis of 6,6-Dimethyl-2-(4-nitrophenyl)-1-(R-phenyl)-4,5,6,7-tetrahydro-1H-4-indolones using a solid sulfated zirconia as catalyst.
Roberto Martinez
2004
Cytotoxic evaluation of substituted azetopyrroloazepinones.
Roberto Martinez
2003
A few comments on the development of organic chemistry in Mexico.
Roberto Martinez
2003
2002
Reaction of 1,2-diaminobenzimidazole with 1-aryl-2-bromo-3-phenylpropanone. synthesis of 2-aryl-3-benzyl-9-aminoimidazo[1,2-A] benzimidazoles.
Roberto Martinez
2002
Synthesis of novel furo, thieno and benzazetoazepines and evaluation of their cytotoxicity.
Roberto Martinez
2002
Synthesis and in vitro cytotoxic activity of pyrrolo[2,3-e]indole derivatives and a dihydro benzoindole analogue.
Roberto Martinez
2002
Cytotoxic activity and QSAR of N,N′-diarylalkanediamides.
Roberto Martinez
2001
2001
Efficient methylation of carboxylic acids with potassium hydroxide/methyl sulfoxide and iodomethane.
Roberto Martinez
2001
Synthesis and cytotoxic evaluation of N1,Nm-bis[(tetrahydrobenzo[a]acridin-12-yl)phenyl]alkanediamides and N1,Nm-bis[(tetrahydrobenzo[c]acridin-7-yl)phenyl]alkanediamides.
Roberto Martinez
2000
Ethyl and methylphenylcarbamates as antihelmintic agents: Theoretical study for predicting their biological activity by PM3.
Roberto Martinez
2000
Molecular association for the design of anti-HIV-1 agents. Conformational study of {3′-azido-3′-deoxythymidine}-{4,5,6,7-tetrahydro-5-methylimidazo-[4,5,1-jk][1,4]benzodiazepin-2(1H)-one} derivatives.
Roberto Martinez
2000